Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Sciences (21574)
- Life Sciences (14897)
- Oncology (14288)
- Diseases (11107)
- Public Health (9409)
-
- Pediatrics (9025)
- Biomedical Informatics (7498)
- Bioinformatics (6790)
- Surgery (5938)
- Neurology (5928)
- Medical Genetics (5734)
- Internal Medicine (5345)
- Cardiology (5246)
- Genetic Phenomena (4771)
- Obstetrics and Gynecology (3711)
- Social and Behavioral Sciences (3508)
- Medical Education (3175)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (2755)
- Mental and Social Health (2732)
- Orthopedics (2673)
- Emergency Medicine (2631)
- Nursing (2533)
- Infectious Disease (2505)
- Pathology (2441)
- Endocrinology, Diabetes, and Metabolism (2367)
- Radiology (2330)
- Cardiovascular Diseases (2313)
- Gastroenterology (2217)
- Institution
-
- The Texas Medical Center Library (18652)
- Thomas Jefferson University (8400)
- Aga Khan University (7545)
- University of Kentucky (2709)
- Children's Mercy Kansas City (2695)
-
- HCA Healthcare (2501)
- Henry Ford Health (2152)
- Zucker School of Medicine at Hofstra/Northwell (2014)
- Providence (1488)
- Himmelfarb Health Sciences Library, The George Washington University (1049)
- Lehigh Valley Health Network (1032)
- Old Dominion University (940)
- Corewell Health (939)
- Rowan University (913)
- Philadelphia College of Osteopathic Medicine (860)
- University of Nebraska Medical Center (859)
- Universitas Indonesia (778)
- LSU Health New Orleans (769)
- University of Texas Rio Grande Valley (738)
- Western University (599)
- Wayne State University (579)
- Gdansk University of Physical Education and Sport (573)
- OhioHealth (572)
- University of Texas MD Anderson Cancer Center (549)
- Wright State University (526)
- Virginia Commonwealth University (516)
- General Organization of Teaching Hospitals and Institutes (GOTHI) (514)
- University of Nebraska - Lincoln (493)
- Edith Cowan University (489)
- Marshall University (464)
- Keyword
-
- Humans (15155)
- Female (6771)
- Male (5909)
- Animals (4265)
- Adult (3272)
-
- Middle Aged (3028)
- Mice (2945)
- Aged (2676)
- Child (2155)
- Adolescent (1655)
- Retrospective Studies (1627)
- COVID-19 (1560)
- United States (1496)
- Treatment Outcome (1354)
- Neoplasms (1174)
- Infant (1081)
- Tumor (1047)
- Risk Factors (1007)
- Pregnancy (984)
- Biomarkers (961)
- Young Adult (961)
- Cancer (891)
- Mutation (864)
- Child, Preschool (861)
- Prospective Studies (847)
- Thomas Jefferson University (812)
- Cell Line (796)
- Carcinoma (792)
- Immunotherapy (768)
- Obesity (739)
- Publication Year
- Publication
-
- Faculty, Staff and Student Publications (10066)
- Faculty, Staff and Students Publications (6915)
- Henry Ford Hospital Medical Journal (2151)
- Journal Articles (2016)
- Manuscripts, Articles, Book Chapters and Other Papers (1314)
-
- Articles, Abstracts, and Reports (858)
- Posters (825)
- Rowan-Virtua Research Day (730)
- Department of Medicine (691)
- Pakistan Journal of Neurological Sciences (PJNS) (684)
- Pediatrics Faculty Publications (680)
- School of Medicine Faculty Publications (633)
- Conference Presentation Abstracts (602)
- Baltic Journal of Health and Physical Activity (573)
- Department of Paediatrics and Child Health (571)
- Department of Pathology and Laboratory Medicine (554)
- Journal of Medicine in Scientific Research (514)
- Research Days (488)
- Markey Cancer Center Faculty Publications (482)
- Jurnal Penyakit Dalam Indonesia (431)
- Children’s Nutrition Research Center Staff Publications (429)
- Jefferson Journal of Psychiatry (426)
- The Texas Heart Institute Journal (419)
- Department of Neurology Faculty Papers (382)
- Journal of the Saudi Heart Association (366)
- Department of Medicine Faculty Papers (361)
- Paediatrics Publications (358)
- Loma Linda University Electronic Theses, Dissertations & Projects (346)
- Obstetrics and Gynaecology, East Africa (346)
- Journal of Patient-Centered Research and Reviews (344)
- Publication Type
Articles 20191 - 20220 of 76889
Full-Text Articles in Medical Specialties
Fibromatous Desmoid Tumor Presenting As A Left Supraclavicular Mass In A 21-Year-Old Female, Robson De Macedo Filho, Christopher Hulsey
Fibromatous Desmoid Tumor Presenting As A Left Supraclavicular Mass In A 21-Year-Old Female, Robson De Macedo Filho, Christopher Hulsey
South Atlantic Division GME Research Day 2024
No abstract provided.
In Utero Presentation Of Cri-Du-Chat Syndrome, Sara Hitt, Claire Mccarthy, Reese Groover, Erika Olsen, Anthony Royek
In Utero Presentation Of Cri-Du-Chat Syndrome, Sara Hitt, Claire Mccarthy, Reese Groover, Erika Olsen, Anthony Royek
South Atlantic Division GME Research Day 2024
No abstract provided.
Food Insecurity In The Behavioral Health Unit, Brianne Kimmet, Maaria Chehab, Alan Whitaker
Food Insecurity In The Behavioral Health Unit, Brianne Kimmet, Maaria Chehab, Alan Whitaker
South Atlantic Division GME Research Day 2024
No abstract provided.
Remdesivir-Induced Bradycardia: A Multicenter Retrospective Analysis, Jomel Jacinto, Tharshikha Pirapakaran, Israa Algburi, Thais Schwartz, Yuhning Linda Hu
Remdesivir-Induced Bradycardia: A Multicenter Retrospective Analysis, Jomel Jacinto, Tharshikha Pirapakaran, Israa Algburi, Thais Schwartz, Yuhning Linda Hu
South Atlantic Division GME Research Day 2024
No abstract provided.
Improving Mental Status Exam Based On Body Mass Index In A Residency Program, Shaina Aifuwa, Murali Sampreeth, Valerie Cordero, Nadia Jacobs, Almari Ginory
Improving Mental Status Exam Based On Body Mass Index In A Residency Program, Shaina Aifuwa, Murali Sampreeth, Valerie Cordero, Nadia Jacobs, Almari Ginory
North Florida Division GME Research Day 2024
No abstract provided.
Pancytopenia And Disseminated Varicella-Zoster Virus In A Patient With T-Cell Lymphoblastic Lymphoma In Maintenance Phase Of Treatment: A Case Report, Kathryn Jordan, Paul Bryant, Clinton Carroll, Jennifer Domm
Pancytopenia And Disseminated Varicella-Zoster Virus In A Patient With T-Cell Lymphoblastic Lymphoma In Maintenance Phase Of Treatment: A Case Report, Kathryn Jordan, Paul Bryant, Clinton Carroll, Jennifer Domm
TriStar Division GME Research Day 2024
No abstract provided.
Mcs Assisted High Risk Multi-Vessel Percutaneous Intervention In Cardiogenic Shock Patient With Lv Thrombus, Amanpreet Kaur, Akhil Gade, Srinivasan Rajaganapathy, Ruben Abreu, Victor Delprincipe
Mcs Assisted High Risk Multi-Vessel Percutaneous Intervention In Cardiogenic Shock Patient With Lv Thrombus, Amanpreet Kaur, Akhil Gade, Srinivasan Rajaganapathy, Ruben Abreu, Victor Delprincipe
North Texas GME Research Forum 2024
Background: Acute coronary syndrome patients presenting with Cardiogenic shock carry a very high mortality risk >70% without appropriate intervention in a timely fashion. Here we present a patient requiring an axial pump mechanical circulatory support despite having an apical thrombus. Case report: 55-year-old male with past medical history of type 2 diabetes mellitus and medication noncompliance was transferred from outside facility for high risk ACS with EKG showing ST segment elevation in inferior and anterolateral leads. Lab showed hsTroponin more than 125K, BG 556, HCO3 17, and Beta hydroxybutyrate of 41.87 indicating DKA. Emergent coronary angiography showed mid LAD artery …
A Retrospective Study On The Effect Of Raas Pathway Inhibitors At Decreasing The Risk Of Acute Coronary Syndrome In Hypertensive Patients With Rheumatoid Arthritis As Compared To Other Antihypertensives, Yousuf Sherwani, Asad Risvi, Senthil Thambidorai
A Retrospective Study On The Effect Of Raas Pathway Inhibitors At Decreasing The Risk Of Acute Coronary Syndrome In Hypertensive Patients With Rheumatoid Arthritis As Compared To Other Antihypertensives, Yousuf Sherwani, Asad Risvi, Senthil Thambidorai
North Texas GME Research Forum 2024
Rheumatoid arthritis (RA) is a chronic multi-system inflammatory disease of which is characterized by articular and extra-articular involvement. Patients with RA have a higher risk of mortality when compared with the general population, which is due predominantly to increased cardiovascular disease. Due to the higher incidence of CVD and MI in RA patients it has been postulated that enhanced systemic inflammation plays an important role in the pathogenesis of CVD in RA patients. Previous studies have shown that ant inflammatory medication such as systemic steroids and immune blockers have been shown to decrease the risk of MI in patients with …
Surgical Margin Analysis In Early-Stage Cervical Cancer: An Hca Retrospective Study, Chrystal Stallworth, Abel Moron, Nicole Tenzel, Timothy Kremer, Michele Mccarroll
Surgical Margin Analysis In Early-Stage Cervical Cancer: An Hca Retrospective Study, Chrystal Stallworth, Abel Moron, Nicole Tenzel, Timothy Kremer, Michele Mccarroll
North Texas GME Research Forum 2024
Objective: This study aimed to compare surgical margin analysis on final pathology in robotic assisted approach hysterectomy vs. all other approaches in early-stage cervical cancer.
Methods: Patients with clinical early-stage disease who underwent total and radical hysterectomy from the years 2018-2023 were categorized into robotic assisted approach group (RAH) vs all other approaches including laparoscopic hysterectomy (LAH), laparoscopic assisted vaginal hysterectomy (LAVH), and open hysterectomy (TAH). Fisher’s exact test was used for analysis of the primary outcome measure.
Results: A total of 92 patients met inclusion criteria. Mode of surgery included: 83 RAH (90.2%), 6 LAH (6.5%), 2 TAH (2.17%), …
Learning Mass Casualty Incident Triage Via Role Play Simulation, Martin Morales-Cruz, Ayanna Walker, Drake Dixon, Latha Ganti, Shayne Gue
Learning Mass Casualty Incident Triage Via Role Play Simulation, Martin Morales-Cruz, Ayanna Walker, Drake Dixon, Latha Ganti, Shayne Gue
North Florida Division GME Research Day 2024
No abstract provided.
Anchoring Sepsis Management: A Retrospective Cohort Study On Fluid Resuscitation In Advanced And End-Stage Renal Disease With Sepsis, Hunter Reed, Abraheim Al-Nasseri, Adam Robarge, Uzman Kazi
Anchoring Sepsis Management: A Retrospective Cohort Study On Fluid Resuscitation In Advanced And End-Stage Renal Disease With Sepsis, Hunter Reed, Abraheim Al-Nasseri, Adam Robarge, Uzman Kazi
West Florida Division GME Research Day 2024
No abstract provided.
Differences In Clinical Interventions And Outcomes In Septic Patients With Heart Failure A Prospective Single Center Experience From The Sepsisquad Investigators, Jose Rodriguez Castro, Manjot Malhi, Rafael Miret, Kristen Santana, Anna Feliszek, Kevin Gopala Rao, Lyanne Rolon, Garrett Wagner, Siddarth Kathuria, Raiko Diaz, Daniel Heller, Mauricio Danckers
Differences In Clinical Interventions And Outcomes In Septic Patients With Heart Failure A Prospective Single Center Experience From The Sepsisquad Investigators, Jose Rodriguez Castro, Manjot Malhi, Rafael Miret, Kristen Santana, Anna Feliszek, Kevin Gopala Rao, Lyanne Rolon, Garrett Wagner, Siddarth Kathuria, Raiko Diaz, Daniel Heller, Mauricio Danckers
East Florida Division GME Research Day 2024
No abstract provided.
Recurrent Intussusception In Child Despite Repeated Surgical Correction, Carlos Cordova, Alexandra Lawlor, Tillie Schumann, Sydney Solomon, Lily Wiedrich
Recurrent Intussusception In Child Despite Repeated Surgical Correction, Carlos Cordova, Alexandra Lawlor, Tillie Schumann, Sydney Solomon, Lily Wiedrich
East Florida Division GME Research Day 2024
No abstract provided.
Exploring The Landscape Of Artificial Intelligence In Rheumatology: Insights, Perceptions, And Future Considerations From A Survey Of United States Rheumatology Fellows, Sathvik Saineni, Richa Purohit, Reanne Mathai, Rajan Sambandan, Richard M. Perez, Neha Bhanusali
Exploring The Landscape Of Artificial Intelligence In Rheumatology: Insights, Perceptions, And Future Considerations From A Survey Of United States Rheumatology Fellows, Sathvik Saineni, Richa Purohit, Reanne Mathai, Rajan Sambandan, Richard M. Perez, Neha Bhanusali
North Florida Division GME Research Day 2024
No abstract provided.
Ai-Supported Diagnosis Of Hypertrophic Cardiomyopathy In A Patient With Adrenal Pheochromocytoma, Muhannad Akel, Ammer Haffar, Christian Zellner
Ai-Supported Diagnosis Of Hypertrophic Cardiomyopathy In A Patient With Adrenal Pheochromocytoma, Muhannad Akel, Ammer Haffar, Christian Zellner
West Florida Division GME Research Day 2024
No abstract provided.
Implementation Of Viz.Ai Augmented Intelligence Software To Reduce Door To Puncture Times And Patient Outcomes At A Comprehensive Stroke Center, Cody Bryant, Brandon Womack, Mason Patel, Sanjay Sharma
Implementation Of Viz.Ai Augmented Intelligence Software To Reduce Door To Puncture Times And Patient Outcomes At A Comprehensive Stroke Center, Cody Bryant, Brandon Womack, Mason Patel, Sanjay Sharma
North Texas GME Research Forum 2024
Introduction: Endovascular therapy (EVT) in the form of mechanical thrombectomy is the mainstay of treatment for acute large vessel occlusion (LVO) ischemic stroke, but its efficacy is highly time sensitive. It is crucial that stroke centers continue to implement process improvements that aim to streamline stroke workflow. Viz.AI is a platform that uses artificial intelligence to automatically detect LVOs with computed tomography (CT) imaging. It provides immediate access to the CT images as well as a platform for centralized communication through the mobile application. We sought to determine if the implementation of Viz.AI at our comprehensive stroke center improved stroke …
Comparing Large Language Models Accuracy In Following Interval Surveillance Colonoscopy Guidelines, Olufemi Osikoya, Gregory Brennan
Comparing Large Language Models Accuracy In Following Interval Surveillance Colonoscopy Guidelines, Olufemi Osikoya, Gregory Brennan
North Texas GME Research Forum 2024
Introduction: Providing pathology results and appropriate recommendations after resection of colon polyps is mandatory. Large language models (LLMs) such as ChatGPT and Google Bard, have shown promise in clinical workflows such as pathology results letters. We tested whether LLMs could provide appropriate surveillance recommendations based on current guidelines from the US multi-society task force for post-colonoscopy follow-up. Methods: Our aim was to compare the accuracy of ChatGPT 3.5, ChatGPT 4, and Google Bard in providing appropriate interval surveillance recommendations. An example prompt being “Write a patient pathology result letter after a colonoscopy with one tubular adenoma polyp (< 10mm) resected. Include recommendations for when the next surveillance colonoscopy should be completed.” Seventeen different post polypectomy surveillance queries and responses were analyzed (correct, partially correct, incorrect) compared to USMSTF guidelines. Results: When …
A Dramatic Case Of Acute Biventricular Failure Secondary To Acute Myocardial Infraction, Heriberto Cantu, Ahmed Mahmood, Luay Alalawi, Thomas Alexander
A Dramatic Case Of Acute Biventricular Failure Secondary To Acute Myocardial Infraction, Heriberto Cantu, Ahmed Mahmood, Luay Alalawi, Thomas Alexander
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
A Case Of Mediastinitis From Esophageal Perforation Presenting As Gastric Volvulus/Para-Esophageal Hernia, Anam Zara, Bushra Bangash, Renu Thomas, Asad Rehman, Karthik Vadamalai, Zuhair Ali, Mishal Mazhar
A Case Of Mediastinitis From Esophageal Perforation Presenting As Gastric Volvulus/Para-Esophageal Hernia, Anam Zara, Bushra Bangash, Renu Thomas, Asad Rehman, Karthik Vadamalai, Zuhair Ali, Mishal Mazhar
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
The Ethical Concerns Of Improper Semaglutide Administration After Acquisition From A Compounded Pharmacy, Syed Basit Haider, Renu Thomas, E’Joven Reed, Aneesha Shaju, Bushra Bangash, Jakob Schnell, Edrianna Mae Ablola
The Ethical Concerns Of Improper Semaglutide Administration After Acquisition From A Compounded Pharmacy, Syed Basit Haider, Renu Thomas, E’Joven Reed, Aneesha Shaju, Bushra Bangash, Jakob Schnell, Edrianna Mae Ablola
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
Anomalous Anomaly: A Rare Case Of The Rca Arising From The Mild Lad, Heriberto Cantu, Luay Alalawi, Ahmed Mahmood, Thomas Alexander
Anomalous Anomaly: A Rare Case Of The Rca Arising From The Mild Lad, Heriberto Cantu, Luay Alalawi, Ahmed Mahmood, Thomas Alexander
Gulf Coast Division GME Research Symposium 2024
No abstract provided.
The Utility Of Cologuard In A Real-World Community Setting, Abhinav K. Rao, Shivam Kalra, Danny Tran, Angeli Patel, Ibrahim Al-Saadi, Levi C. Diggins, Ian Whitaker, Shannon Kang, Kunaal Patel, Eyad Gharaibeh, Ali Khalifa, Don C. Rockey, Brett Van Leer-Greensberg
The Utility Of Cologuard In A Real-World Community Setting, Abhinav K. Rao, Shivam Kalra, Danny Tran, Angeli Patel, Ibrahim Al-Saadi, Levi C. Diggins, Ian Whitaker, Shannon Kang, Kunaal Patel, Eyad Gharaibeh, Ali Khalifa, Don C. Rockey, Brett Van Leer-Greensberg
South Atlantic Division GME Research Day 2024
No abstract provided.
A Challenging Diagnosis Of Intestinal Tuberculosis Mimicking Crohn's Disease, Justin Sanchez, Gabriel Gonzales, Monte Troutman
A Challenging Diagnosis Of Intestinal Tuberculosis Mimicking Crohn's Disease, Justin Sanchez, Gabriel Gonzales, Monte Troutman
North Texas GME Research Forum 2024
Intestinal tuberculosis (ITB) is an underrecognized disease that shares many clinical, radiologic, endoscopic, and pathologic features with Crohn's disease, making differentiation difficult. This poses a significant problem as initiation of immunosuppressives for an assumed diagnosis of CD in a patient with ITB can lead to exacerbation of infection and life-threatening consequences. A 30-year-old Nepali man with a medical history only significant for Raynaud disease presented with a febrile illness, right lower quadrant abdominal pain, and productive cough over the course of a month. He immigrated from Nepal 3 years prior to presentation, denying other risk factors or specific symptoms of …
Examining Menstrual Health Experiences In Philadelphia, Pa: A Qualitative Investigation, Allison Casola, Oriana Pando, Lynette Medley, Brianna Kunes, Nya Mcglone, Olivia Rea
Examining Menstrual Health Experiences In Philadelphia, Pa: A Qualitative Investigation, Allison Casola, Oriana Pando, Lynette Medley, Brianna Kunes, Nya Mcglone, Olivia Rea
Department of Family & Community Medicine Faculty Papers
BACKGROUND: While menstruation is a physiologic process, it remains highly stigmatized. Despite the sheer number of menstruators, menstruation is a highly individualized experience, with wide variation in duration, symptoms, and management. This wide variability lends itself to large disparities in access to menstruation management products and subsequently the lived experience of menstruators.
OBJECTIVES: The research team sought to understand lived menstrual experiences, symptoms, management tactics, and commonly used and desired resources among 20 cisgendered women aged 18-45 years in Philadelphia.
DESIGN: This project was a qualitative research study.
METHODS: We used a collaborative, community-based participatory research approach with No More …
Epidemiologic Profile And Treatment Analysis Of Cervicalgia In Patients With Migraine Vs. Tension-Type Headaches From A Multicenter Electronic Medical Record Database (Trinetx), Ethan J. Le, Victor S. Wang, Md, Hsiangkuo Yuan, Md, Phd
Epidemiologic Profile And Treatment Analysis Of Cervicalgia In Patients With Migraine Vs. Tension-Type Headaches From A Multicenter Electronic Medical Record Database (Trinetx), Ethan J. Le, Victor S. Wang, Md, Hsiangkuo Yuan, Md, Phd
Alpha Omega Alpha Research Symposium Posters
BACKGROUND
• Cervicalgia, or chronic neck pain, remains an understudied and undertreated comorbid condition in patients with headache disorders that benefits from both pharmacologic and non-pharmacologic treatment profiles.
• Cervicogenic headaches present a significant global healthcare burden, with estimates projecting up to 4.1% of the global population and 20% of headache complaints are attributed to cervicalgia (Fernandez et al. 2020).
• What is the global demographic, treatment, and migraine preventive profile of cervicalgia in patients with either concurrent migraine (CM) or tension-type (CT) headaches?
Preoperative Predictors Of Arthroscopic Partial Meniscectomy Outcomes: The Apm Index Score, Natalie Lowenstein, Yuchiao Chang, Hanna Mass, Angela M. Mercurio, Chierika Ukogu, Jeffrey N. Katz, Elizabeth G. Matzkin
Preoperative Predictors Of Arthroscopic Partial Meniscectomy Outcomes: The Apm Index Score, Natalie Lowenstein, Yuchiao Chang, Hanna Mass, Angela M. Mercurio, Chierika Ukogu, Jeffrey N. Katz, Elizabeth G. Matzkin
Alpha Omega Alpha Research Symposium Posters
Problem Statement:
- Arthroscopic partial meniscectomy (APM) has been shown to be the most common meniscal surgical treatment in the United States
- Pre-op risk factors known to contribute to poor outcomes after APM:
- Symptom duration and radiographic OA at baseline
- Baseline knee functional score, location of meniscal tear, BMI, activity level, age, sex, and chondral damage on MRI
Project AIM:
To create an index score using easily available preoperative risk factors such as Kellgren-Lawrence (KL) grade, age, duration of symptoms, BMI, activity level, and preoperative outcome scores to predict the …
Determining Effective Treatment Regimens For Breast Cancer Using Combined Immunotherapy And Chemotherapy In Vivo, Akhila Kunuthuru
Determining Effective Treatment Regimens For Breast Cancer Using Combined Immunotherapy And Chemotherapy In Vivo, Akhila Kunuthuru
AUCTUS: The Journal of Undergraduate Research and Creative Scholarship
Breast cancer has the highest incidence rate of all cancers globally in women, and those of African descent, especially West African females, face higher rates of triple-negative breast cancer (TNBC), a more aggressive form of breast cancer. Immunotherapy for breast cancer is a relatively new treatment option, and research is ongoing to identify the best combination treatments for increasing survival of those diagnosed with TNBC. Eganelisib (IPI-549: a PI3K-gamma inhibitor that works to shift M2 macrophages to M1 to augment T cell function) with other combinatory treatments has shown promising results in reducing tumor growth and increasing survival in mice. …
Informing A Care Plan For Hepatitis C Treatment On The Street, Claire Campbell
Informing A Care Plan For Hepatitis C Treatment On The Street, Claire Campbell
Scripps Senior Theses
This thesis aims to use community knowledge to inform clinical street treatment of Hepatitis C and to unpack the intersections of social systems within the realms of Street Medicine and healthcare for the unsheltered unhoused population. During the summer of 2023, 15 qualitative interviews were conducted with patients of the USC Keck School of Medicine Department of Street Medicine who received treatment for Hepatitis C infections. Using grounded theory analysis, participant responses were analyzed to identify key concepts and ideas from interview transcripts. Core themes fell into the following categories: how treatment affected patients’ lives, facilitators and barriers to treatment, …
The Efficacy Of Botulinum Toxin Use In Service Members And Veterans With Migraine And Post-Traumatic Headache Disorders: A Scoping Review, Qing Zhao Ruan, Daniel J Pak, David E Reece, Rohan Jotwani, Sean Li, Moises Dominguez, Alan David Kaye, R Jason Yong, Abdulrazaq Albilali, Sadiq Bhayani, Jamal Hasoon, Michael E Schatman, Jun Beom Ku, Thomas T Simopoulos, Sait Ashina, Christopher L Robinson
The Efficacy Of Botulinum Toxin Use In Service Members And Veterans With Migraine And Post-Traumatic Headache Disorders: A Scoping Review, Qing Zhao Ruan, Daniel J Pak, David E Reece, Rohan Jotwani, Sean Li, Moises Dominguez, Alan David Kaye, R Jason Yong, Abdulrazaq Albilali, Sadiq Bhayani, Jamal Hasoon, Michael E Schatman, Jun Beom Ku, Thomas T Simopoulos, Sait Ashina, Christopher L Robinson
Faculty, Staff and Student Publications
Objective: To delineate the trend of use of botulinum toxin, including onabotulinum toxinA (OTA), in active military personnel and veterans with the diagnoses of migraine and post-traumatic headache (PTH) and describe the efficacy of botulinum toxin administration.
Background: Service members and veterans represent a unique population in the medical management of headache disorders, particularly migraine. They exhibit higher susceptibility to pain of greater intensity and longer durations, possibly due to their history of exposure to combat, trauma, and the associated psychological stresses. Given the burden and morbid nature of these headache disorders, prophylactic measures to reduce migraine attacks and disability …
Phase 1 Trial Of Tpi 287, A Microtubule Stabilizing Agent, In Combination With Bevacizumab In Adults With Recurrent Glioblastoma, Samuel A Goldlust, Louis B Nabors, Sigmund Hsu, Nimish Mohile, Paul J Duic, Tara Benkers, Samuel Singer, Mayank Rao, Lori Cappello, Sandra L Silberman, George Farmer
Phase 1 Trial Of Tpi 287, A Microtubule Stabilizing Agent, In Combination With Bevacizumab In Adults With Recurrent Glioblastoma, Samuel A Goldlust, Louis B Nabors, Sigmund Hsu, Nimish Mohile, Paul J Duic, Tara Benkers, Samuel Singer, Mayank Rao, Lori Cappello, Sandra L Silberman, George Farmer
Faculty, Staff and Student Publications
BACKGROUND: Recurrent glioblastoma (rGBM) has limited treatment options. This phase 1 protocol was designed to study the safety and preliminary efficacy of TPI 287, a central nervous system penetrant microtubule stabilizer, in combination with bevacizumab (BEV) for the treatment of rGBM.
METHODS: GBM patients with up to 2 prior relapses without prior exposure to anti-angiogenic therapy were eligible. A standard 3 + 3 design was utilized to determine the maximum tolerated dose (MTD) of TPI 287. Cohorts received TPI 287 at 140-220 mg/m
RESULTS: Twenty-four patients were enrolled at 6 centers. Treatment was generally well tolerated. Fatigue, myelosuppression, and peripheral …