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2003

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Articles 511 - 539 of 539

Full-Text Articles in Medicine and Health Sciences

Repair Of Myeloschisis Defect With Tutoplast, Mehmet Dumlu Aydin Jan 2003

Repair Of Myeloschisis Defect With Tutoplast, Mehmet Dumlu Aydin

Turkish Journal of Medical Sciences

umlu AYDIN Department of Neurosurgery, Faculty of Medicine, Atatürk University, Erzurum - Turkey

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Treatment Of Clot Retention With Intravesical Streptokinase Instillation, Sema Uğuralp, Necla Gürbüz, Tamer Baysal Jan 2003

Treatment Of Clot Retention With Intravesical Streptokinase Instillation, Sema Uğuralp, Necla Gürbüz, Tamer Baysal

Turkish Journal of Medical Sciences

RALP^1 Necla GÜRBÜZ^1 Tamer BAYSAL^2 Departments of ^1Pediatric Surgery, and ^2Radiology, Faculty of Medicine, Turgut Özal Medical Center, İnönü University, Malatya, Turkey

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Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven Jan 2003

Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven

Turkish Journal of Medical Sciences

The protein p53 seems to be related to the suppression of cell proliferation. Positive tissues appear to have a higher proliferative activity than negative tissues. Mutation of the p53 tumour suppressor gene has been demonstrated in a large proportion of human head and neck tumours, although no formal evidence of functional aberration has been shown p53 may have importance during the early stage of malignancy. The aim of this study was to evaluate the role of the p53 tumour suppressor gene in the pathogenesis of odontogenic cysts. Expression of abnormal p53 protein is a widely recognised marker of malignancy. Expression …

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Drug Resistance In Acute Leukaemia And Reversion, Jean-Pierre Marie, Ollivier Legrand Jan 2003

Drug Resistance In Acute Leukaemia And Reversion, Jean-Pierre Marie, Ollivier Legrand

Turkish Journal of Medical Sciences

No abstract provided.

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The Ebmt Activity Survey On Hematopoietic Stem Cell Transplantation: A Novel Instrument For Quality Control, Alois Gratwohl, Helen Baldomero, Alvaro Urbano Ispizua Jan 2003

The Ebmt Activity Survey On Hematopoietic Stem Cell Transplantation: A Novel Instrument For Quality Control, Alois Gratwohl, Helen Baldomero, Alvaro Urbano Ispizua

Turkish Journal of Medical Sciences

The hematopoietic stem cell transplant activity survey of the European Group for Blood and Marrow Transplantation (EBMT) represents a novel modern tool in health care management. Introduced in 1990, it captures annual numbers of hematopoietic stem cell transplantation (HSCT) by indication, donor type and stem cell source from each individual European transplant team. Supplemented by demographical data and economic factors, team density and transplant rates can be calculated and the impact of economics on HSCT rates can be assessed. As documented in the present analysis, a total of 19,668 HSCT were performed in Europe in 2001 by 599 teams in …

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Development Of A Diagnostic And Screening Elisa System For Measuring Tetanus Antitoxoid Levels, Cemaletti̇n Aybay, Resul Karakuş, Ahmet Gökhan Gündoğdu Jan 2003

Development Of A Diagnostic And Screening Elisa System For Measuring Tetanus Antitoxoid Levels, Cemaletti̇n Aybay, Resul Karakuş, Ahmet Gökhan Gündoğdu

Turkish Journal of Medical Sciences

Tetanus is a vaccine-preventable disease of global importance. When acquired it has a high mortality rate. Screenings of special subpopulations such as women of childbearing age provide important clues about tetanus vaccination coverage, and tools for mass protective measures, e.g, protective measures for neonatal tetanus. In addition to its reliability and sensitivity, the main advantage of a mass-screening tool should be its cost-effectiveness. We aimed to develop a cost-effective and sensitive enzyme-linked immunosorbent assay (ELISA) that can be used for diagnostic research as well as mass screening purposes for antitetanus antibodies. Our in-house antitetanus ELISA was validated and tested for …

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Nicotine Dependence In Medical Students And Physicians In The Lakes Region, Rezan Demi̇ralay Jan 2003

Nicotine Dependence In Medical Students And Physicians In The Lakes Region, Rezan Demi̇ralay

Turkish Journal of Medical Sciences

This study was carried out to evaluate the level of physical nicotine dependence in medical students and physicians working in the Lakes region, Turkey. The standardized Fagerström test of nicotine dependence questionnaire was given to 135 physicians and 61 medical students who smoked daily. The rate of daily smoking was 28.4% in medical students and 33.7% in physicians. Average Fagerström test for nicotine dependence scores were 3.98 ± 2.69 for medical students, 3.69 ± 3.05 for general practitioners, 3.06 ± 2.23 for research assistants and 3.34 ± 2.88 for specialist physicians. Of the medical students, 15 (24.6%) indicated high nicotine …

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Paraplegia Due To Extramedullary Hematopoiesis In The Thalassemia Intermedia, Şule Peker, Mehmet Çelebi̇soy, İsmai̇l Akkol, Hamdi̇ Bezi̇rci̇oğlu Jan 2003

Paraplegia Due To Extramedullary Hematopoiesis In The Thalassemia Intermedia, Şule Peker, Mehmet Çelebi̇soy, İsmai̇l Akkol, Hamdi̇ Bezi̇rci̇oğlu

Turkish Journal of Medical Sciences

ER^1, Mehmet ÇELEBİSOY^1, İsmail AKKOL^2, Hamdi BEZİRCİOĞLU^2 ^1Atatürk Education and Research Hospital Second Neurology Clinic, İzmir - Turkey ^2Atatürk Education and Research Hospital Neurosurgery Clinic, İzmir - Turkey

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A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş Jan 2003

A Novel Method Of Reporting C-Erbb-2 Overexpression; Correlation With Grade But Not With Other Prognostic Parameters In Breast Cancer, Mustafa Samur, Şeyda Karaveli̇, Hakan Bozcuk, Eli̇f Pestereli̇, Mustafa Özdoğan, Mustafa Yildiz, Mehmet Artaç, Burhan Savaş

Turkish Journal of Medical Sciences

Overexpression of erbB-2 protein is a marker of clinically aggressive behavior in breast cancer patients. In general erbB-2 status is reported on a scale from negative to 3+, depending on staining intensity, if more than 10% of the tumor cells are stained. However, the original definition does not take into account the percentage of stained cells in detail, since all samples score in the same way if they are above the cut-off, established at 10%. In this study, we evaluated the erB-B2 overexpression by immunohistochemistry in 169 patients and evaluated any correlation with the other well known prognostic parameters. We …

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Benign Localized Fibrous Tumor Of The Pleura: Report Of Three Cases And A Review Of The Literature, Ni̇hal Kilinç, Ali̇ Kemal Uzunlar Jan 2003

Benign Localized Fibrous Tumor Of The Pleura: Report Of Three Cases And A Review Of The Literature, Ni̇hal Kilinç, Ali̇ Kemal Uzunlar

Turkish Journal of Medical Sciences

LINÇ, Ali Kemal UZUNLAR Department of Pathology, Faculty of Medicine, Dicle University, Diyarbakır - Turkey

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Haemophilus Parainfluenzae Endocarditis, Emi̇ne Alp, Orhan Yildiz, Bi̇lgehan Aygen, Bülent Sümerkan Jan 2003

Haemophilus Parainfluenzae Endocarditis, Emi̇ne Alp, Orhan Yildiz, Bi̇lgehan Aygen, Bülent Sümerkan

Turkish Journal of Medical Sciences

No abstract provided.

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Suicide In The Province Of Eskişehir, Turkey: The Approach Of Forensic Medicine, Yasemi̇n Günay Balci, Emre Albek Jan 2003

Suicide In The Province Of Eskişehir, Turkey: The Approach Of Forensic Medicine, Yasemi̇n Günay Balci, Emre Albek

Turkish Journal of Medical Sciences

In the present study, a retrospective evaluation of suicides in the province of Eskişehir in 1997-1999 is made. Investigation reports of the Central Prosecutor's Office were obtained and the demographic data of the victims as well as the judicial criteria for the classification as "suicide" were evaluated. There were 94 cases of suicide and 65 of them (69.1%) involved males. Age distribution showed a predominance in the age group of 15-34 years. Suicide in males over 55 years of age occurred more frequently than in females (p < 0.05). Causes of death in suicides included hanging in 68.0% of cases, firearm wounding in 16.0%, jumping from heights in 7.4%, drug intake in 5.3%, railway suicides in 2.2% and butane inhalation in 1.1%; 79.8% of suicides occurred in residences. In 93.6% of the cases, scene investigation reports and drawings were obtainable, while photographs of the scene or of the victim were present in 53.2% of cases. A forensic medicine specialist's inquest had been performed in all cases whilst a medico-legal autopsy had been carried out in only 29.8% of cases. Death certificates were issued following an inquest and scene investigation in 66 cases. Medico-legal autopsies were performed in 73.3% of the cases of firearm wounding, 25.0% of the cases of hanging and 6.7% of suicides committed by other means. In conclusion, we emphasize the importance of a medico-legal autopsy in all suicide cases.

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A Cerebral Hydatid Cyst Case First Presenting With Gerstmann's Syndrome: A Case Report And Literature Review, Mehmet Dumlu Aydin, Nazan Aydin Jan 2003

A Cerebral Hydatid Cyst Case First Presenting With Gerstmann's Syndrome: A Case Report And Literature Review, Mehmet Dumlu Aydin, Nazan Aydin

Turkish Journal of Medical Sciences

umlu AYDIN^1 Nazan AYDIN^2 Departments of ^1Neurosurgery , ^2Psychiatry, Faculty of Medicine, Atatürk University, Erzurum - Turkey

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Evaluation Of Phagocytic Function Of The Spleen After Splenic Artery Ligation In Secondary Hypersplenism, Celaletti̇n Vatansev, Şaki̇r Teki̇n, Mustafa Şahi̇n, Mustafa Serdengeçti̇, Mustafa C. Avunduk Jan 2003

Evaluation Of Phagocytic Function Of The Spleen After Splenic Artery Ligation In Secondary Hypersplenism, Celaletti̇n Vatansev, Şaki̇r Teki̇n, Mustafa Şahi̇n, Mustafa Serdengeçti̇, Mustafa C. Avunduk

Turkish Journal of Medical Sciences

The aim of this study was to investigate the effects of splenic artery ligation on the phagocytic functions and morphology of the spleen in rabbits in which secondary hypersplenism was induced by splenic vein ligation (SVL). Thirty New Zealand-type rabbits were included in this study. The rabbits were separated into three groups of 10 subjects each. The first group underwent laparotomy, and the second and third groups underwent laparotomy + splenic vein ligation. At the end of the fourth week, the first and second groups underwent laparotomy while the third group underwent laparotomy + splenic artery ligation. At the end …

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Problems In Urinary Iodine Determination Methods And An Automated Kinetic Assay As A Solution, Mustafa Gültepe, Ömer Özcan, Osman Meti̇n İpçi̇oğlu, Kadi̇r Avşar Jan 2003

Problems In Urinary Iodine Determination Methods And An Automated Kinetic Assay As A Solution, Mustafa Gültepe, Ömer Özcan, Osman Meti̇n İpçi̇oğlu, Kadi̇r Avşar

Turkish Journal of Medical Sciences

Accurate, fast and economical urinary iodine measurement is very important in diagnosing iodine deficiency disorders. The urinary iodine determination method using ammonium persulfate digestion based on the Sandell-Kolthoff reaction was optimized and modified to kinetic and automated assay. Ammonium persulfate digestion was performed at +95 ºC in a water-bath to ± 0.1 ºC precision. The performance of both the Sandell-Kolthoff reaction at 37 ºC and its kinetic measurement at 340 nm was tested in a random access automated analyzer. For method comparison, urinary iodine concentrations were measured using both the conventional chloric acid digestion method and the kinetic automated method …

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Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür Jan 2003

Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür

Turkish Journal of Medical Sciences

Several factors may be responsible for the high prevalence of atherosclerosis in diabetes mellitus, including alterations in reverse cholesterol transport. In the present study, the activity of plasma lecithin:cholesterol acyltransferase (LCAT) and the cholesteryl ester transfer rate, and concentrations of lipids and lipoproteins were measured in 11 patients with insulin-dependent diabetes mellitus (type 1), 42 patients with noninsulin-dependent diabetes mellitus (type 2) and compared with those in age-matched control groups (Control I, n = 14; and Control II, n = 29, respectively). No statistically significant differences were observed in plasma total cholesterol, triglyceride, ester cholesterol or very low density lipoprotein …

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Subtalar Dislocations: A Report Of Two Cases, Özcan Pehli̇van, Can Solakoğlu, İbrahi̇m Akmaz Jan 2003

Subtalar Dislocations: A Report Of Two Cases, Özcan Pehli̇van, Can Solakoğlu, İbrahi̇m Akmaz

Turkish Journal of Medical Sciences

HLİVAN Can SOLAKOĞLU İbrahim AKMAZ Department of Orthopedics and Traumatology, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul - Turkey

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Peritoneal Defense Mechanisms, Toni̇ Hau Jan 2003

Peritoneal Defense Mechanisms, Toni̇ Hau

Turkish Journal of Medical Sciences

No abstract provided.

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Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu Jan 2003

Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu

Turkish Journal of Medical Sciences

The role of endogenous fibrinolysis in cerebral infarction has been investigated, but with conflicting results. In this study, variations of tissue-type plasminogen activator (t-PA) antigen concentrations over time after stroke were examined at the acute and subacute phases of ischemic stroke in a group of patients and in a control group. The relationships between t-PA levels and stroke severity, lesion volume and clinical status were also investigated. This study was carried out in 45 patients with acute ischemic stroke and 21 control subjects who had similar characteristics. Levels of t-PA mass concentration were measured via the ELISA, while Student's t, …

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Carcinoma Of The Cecum: An Unusual Cause Of Fournier's Gangrene, Safvet Örs, Oğuz Ekmekci̇oğlu, Ati̇la Çoruh, Gali̇p K. Günay Jan 2003

Carcinoma Of The Cecum: An Unusual Cause Of Fournier's Gangrene, Safvet Örs, Oğuz Ekmekci̇oğlu, Ati̇la Çoruh, Gali̇p K. Günay

Turkish Journal of Medical Sciences

RS^1 Oğuz EKMEKCİOĞLU^2 Atila ÇORUH^1 Galip K. GÜNAY^1 Departments of ^1Plastic Surgery and ^2Urology, Faculty of Medicine, Erciyes University Kayseri - TURKEY

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Vitamin D Dependent Down Regulation Of Arf1 Gene In Human Leukemia Cell Line Hl-60, Hakan Savli Jan 2003

Vitamin D Dependent Down Regulation Of Arf1 Gene In Human Leukemia Cell Line Hl-60, Hakan Savli

Turkish Journal of Medical Sciences

VLI Department of Medical Biology, Faculty of Medicine, Kocaeli University, Kocaeli - Turkey

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The Behaviour And Attitude Of Physicians In The Lakes Region Towards Smoking, Rezan Demi̇ralay Jan 2003

The Behaviour And Attitude Of Physicians In The Lakes Region Towards Smoking, Rezan Demi̇ralay

Turkish Journal of Medical Sciences

This study was carried out on 401 physicians who work in the Lakes region, Turkey, to assess their behaviour and attitude towards smoking. A questionnaire based on guidelines and standardised questions prepared by the World Health Organization was given to physicians. Of the physicians, 136 (33.9%) had never tried to smoke in their lives and 45 (11.2%) were former smokers. Of the 220 (54.9%) physicians who had smoked for at least 6 months in their lifetime, 46 (11.5%) were ex-smokers. Of the current smokers, 135 (77.6%) were daily smokers and 39 (22.4%) were occasional smokers. Fifty-two (43.7%) general practitioners, 34 …

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Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt Jan 2003

Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt

Turkish Journal of Medical Sciences

Tissue perfusion is determined by both blood vessel geometry and the rheological properties of blood. Blood is a non-Newtonian fluid, its viscosity being dependent on flow conditions. Blood and plasma viscosities, as well as the rheological properties of blood cells (e.g., deformability and aggregation of red blood cells), are influenced by disease processes and extreme physiological conditions. These rheological parameters may in turn affect the blood flow in vessels, and hence tissue perfusion. Unfortunately it is not always possible to determine if a change in rheological parameters is the cause or the result of a disease process. The hemorheology-tissue perfusion …

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The Pathology Of Echinococcosis And The Current Echinococcosis Problem In Western Turkey (A Report Of Pathologic Features In 80 Cases, M. Şerefetti̇n Canda, Meri̇h Güray, Tülay Canda Jan 2003

The Pathology Of Echinococcosis And The Current Echinococcosis Problem In Western Turkey (A Report Of Pathologic Features In 80 Cases, M. Şerefetti̇n Canda, Meri̇h Güray, Tülay Canda

Turkish Journal of Medical Sciences

Echinococcosis is an infection caused by Echinococcus granulosus and E. multilocularis. It manifests as cyst formations in various organs, affecting both humans and animals. The cysts may be unilocular (E. granulosus) or multilocular (E. multilocularis). Multilocular cysts have particular significance, for their macroscopic appearance is reminiscent of malignant tumors and their prognosis is poor. The purpose of this study is to describe our cases and to start a discussion on the current echinococcosis problem in İzmir, western Anatolia. The pathological features of 80 cases of echinococcosis diagnosed at Dokuz Eylül University Pathology Department over the last 21 years have been …

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Determination Of Alkaline Phosphatase Activity In Patients With Different Zinc Metabolic Disorders, Zine Kechrid, Rabah Kenouz Jan 2003

Determination Of Alkaline Phosphatase Activity In Patients With Different Zinc Metabolic Disorders, Zine Kechrid, Rabah Kenouz

Turkish Journal of Medical Sciences

Our purpose was to investigate the effect of different zinc metabolic disorders on alkaline phosphatase activity. Serum zinc, glucose and alkaline phosphatase activity were studied in 32 patients with liver cirrhosis, 30 with chronic renal failure and 42 with insulin-dependent diabetes mellitus (IDDM) compared to 42 healthy volunteers. Serum glucose concentration was significantly higher (P < 0.001) in IDDM and liver cirrhosis patients (P < 0.05) compared to the controls. Serum zinc concentrations tended to be lower in all different diseases but did not reach statistical significance. Alkaline phosphatase activity was higher in IDDM (P < 0.05) and liver cirrhosis patients (P < 0.01) compared with the controls. No positive correlation between serum zinc and alkaline phosphatase activity was recorded in any disease. In conclusion, the investigated diseases did not affect the level of serum zinc; however, there was an alteration in alkaline phosphatase activity in patients suffering from diabetes and liver cirrhosis. Consequently, this may be attributed to the functional disturbance that occurred in these patients. Finally, zinc concentration did not follow alkaline phosphatase activity as indicated by the weak correlation obtained.

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The Role Of Oxidative Stress In Alzheimer's Disease, Robin Petroze Jan 2003

The Role Of Oxidative Stress In Alzheimer's Disease, Robin Petroze

Kaleidoscope

Over four million individuals in the United States currently suffer from Alzheimer's disease (AD), a devastating disorder of progressive dementia. Within the next several decades, AD is expected to affect over 22 million people globally. AD can only be definitively diagnosed by postmortem examination. Thus, investigation into the specific pathogenesis of neuronal degeneration and death in AD on a biochemical level is essential for both earlier diagnosis and potential treatment and prevention options. Overproduction of amyloid [3-peptide (A[3) in the brain leads to both free radical oxidative stress and toxicity to neurons in AD. My undergraduate biochemical studies with regard …

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Perceived Motivational Factors Among Allied Health Managers And Subordinates, Sandra Barker Dunbar Jan 2003

Perceived Motivational Factors Among Allied Health Managers And Subordinates, Sandra Barker Dunbar

Internet Journal of Allied Health Sciences and Practice

This exploratory study sought to assess the differences in perceptions among allied health managers and subordinates regarding motivation in the workplace due to a paucity of literature in this area. With an increased demand for higher productivity, an ever-changing health care system and managed care restrictions, it is also important to understand what may motivate individuals who are functioning within different work environments than in the past. The hygiene and motivator factors from Herzberg’s two factor theory created the independent variables which overlap with Maslow’s Hierarchy of Needs descriptions. These included Basic (job security, salary etc.), Safety (work conditions, pension), …

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A Comparison Of Learning Styles Among Seven Health Professions: Implications For Optometric Education, Patrick C. Hardigan, Stanley R. Cohen Jan 2003

A Comparison Of Learning Styles Among Seven Health Professions: Implications For Optometric Education, Patrick C. Hardigan, Stanley R. Cohen

Internet Journal of Allied Health Sciences and Practice

Educational research and development efforts are most often directed at the improvement of teaching while neglecting students’ learning styles. Besides being marginally effective, an exclusive focus on improving teaching methods may lead to reinforcement of inappropriate and nontransferable learning strategies. As such, this study is being undertaken to determine if differences in personality style exist among health profession students. This retrospective-descriptive study tested the null hypothesis “there is no difference in personality traits between osteopathic medicine, pharmacy, physical therapy, physician assistant, dental medicine, optometry and occupational therapy students.” Differences as well as similarities were discovered across all seven professions. Implications …

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Problem-Based Learning In Allied Health And Medicine, Todd A. Mcloda Jan 2003

Problem-Based Learning In Allied Health And Medicine, Todd A. Mcloda

Internet Journal of Allied Health Sciences and Practice

This paper reviews the applicability and procedures for the adoption of problem-based learning in allied health and medical education. A summary of PBL as a practical innovation for professional preparatory programs is included as well as an overview of the features and evaluative techniques of PBL. The paper is directed at PBL in health and medicine but those educators seeking to enhance integrative thought processes, problem-solving, creativity, critical thinking, interpersonal communications, and resourcefulness among students are advised to consider PBL as an alternative approach to teaching and content delivery.

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