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Articles 781 - 810 of 1481

Full-Text Articles in Medicinal Chemistry and Pharmaceutics

Erratum: Flavone Glycosides From Commercially Available Lophatheri Herba And Their Chromatographic Fingerprinting And Quantitation (Journal Of Food And Drug Analysis (2015) 23 (821-827)), J.-S. Fan, I.-J. Lee, Y.-L. Lin Jul 2020

Erratum: Flavone Glycosides From Commercially Available Lophatheri Herba And Their Chromatographic Fingerprinting And Quantitation (Journal Of Food And Drug Analysis (2015) 23 (821-827)), J.-S. Fan, I.-J. Lee, Y.-L. Lin

Journal of Food and Drug Analysis

[No abstract available]

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Correlation Between Drug-Drug Interaction-Induced Stevens-Johnson Syndrome And Related Deaths In Taiwan, F.-J. Cheng, F.-K. Syu, K.-H. Lee, F.-C. Chen, C.-H. Wu, C.-C. Chen Jul 2020

Correlation Between Drug-Drug Interaction-Induced Stevens-Johnson Syndrome And Related Deaths In Taiwan, F.-J. Cheng, F.-K. Syu, K.-H. Lee, F.-C. Chen, C.-H. Wu, C.-C. Chen

Journal of Food and Drug Analysis

Concomitant use of some drugs can lead to interactions between them resulting in severe adverse effects. To date, there are few reports of incidences of Stevens-Johnson syndrome (SJS) associated with combination drug administration. Therefore, we studied the relationship between drug combinations and SJS-related mortality, with the hope that a retrospective study of this nature would provide information crucial for the prevention of future drug-drug interaction related deaths attributable to SJS. This retrospective longitudinal study used mortality cases from 1999 to 2008 that were diagnosed as erythema multiforme (International Classification of Diseases, Ninth Revision, Clinical Modification 695.1) from the National Health …

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Phytochemical Standardization, Antioxidant, And Antibacterial Evaluations Of Leea Macrophylla: A Wild Edible Plant, A. Joshi, S.K. Prasad, V.K. Joshi, S. Hemalatha Jul 2020

Phytochemical Standardization, Antioxidant, And Antibacterial Evaluations Of Leea Macrophylla: A Wild Edible Plant, A. Joshi, S.K. Prasad, V.K. Joshi, S. Hemalatha

Journal of Food and Drug Analysis

In Ayurveda, Leea macrophylla Roxb. ex Hornem. (Leeaceae) is indicated in worm infestation, dermatopathies, wounds, inflammation, and in symptoms of diabetes. The present study aims to determine the antioxidant and antibacterial potential of ethanolic extract and its different fractions of Leea macrophylla root tubers using phytochemical profiling which is still unexplored. Quantitative estimations of different phytoconstituents along with characterization of ethanol extract using high performance liquid chromatography (HPLC) were performed using chlorogenic acid as a marker compound for the first time. The extract and its successive fractions were also evaluated for in vitro antioxidant activity using different models. The extract …

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Acute Pancreatitis In Patients With Type 2 Diabetes Mellitus Treated With Dipeptidyl Peptidase-4 Inhibitors, T.-L. Yang, M.-C. Shen, M.-L. Yu, Y.-B. Huang, C.-Y. Chen Jul 2020

Acute Pancreatitis In Patients With Type 2 Diabetes Mellitus Treated With Dipeptidyl Peptidase-4 Inhibitors, T.-L. Yang, M.-C. Shen, M.-L. Yu, Y.-B. Huang, C.-Y. Chen

Journal of Food and Drug Analysis

Dipeptidyl peptidase (DPP)-4 inhibitors are approved for use in monotherapy or in combination therapy for patients with type 2 diabetes mellitus for However, numerous reports of DPP-4 inhibitors induced acute pancreatitis were made through the US Food and Drug Administration Adverse Event Reporting System, and this led to a revision in the prescribing information for these drugs. Therefore, this study is designed to evaluate DPP-4 inhibitors induced acute pancreatitis via the spontaneous adverse drug reactions (ADRs) reporting system in a medical center. In four of 2305 ADR cases, it is suspected that DPP-4 inhibitors induced moderate to serious acute pancreatitis. …

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Evaluation Of Boldenone As A Growth Promoter In Broilers: Safety And Meat Quality Aspects, A. Elmajdoub, A. Garbaj, S. Abolghait, A. El-Mahmoudy Jul 2020

Evaluation Of Boldenone As A Growth Promoter In Broilers: Safety And Meat Quality Aspects, A. Elmajdoub, A. Garbaj, S. Abolghait, A. El-Mahmoudy

Journal of Food and Drug Analysis

The object of this study was to evaluate the safety and meat quality criteria in broilers following intramuscular injection of boldenone. Twenty-four broiler chicks, divided into two groups, were used in the present study. Boldenone was injected intramuscularly at a single-dose level of 5 mg/kg body weight into 12 broiler chicks at 2 weeks old; the other 12 chicks were injected with sesame oil and kept as controls. Blood samples were collected from the wing and metatarsal veins after 1, 2, and 3 weeks through the experimental course for hematological and clinic-chemical safety parameters. On the last day, chicks were …

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Rapid Screening Of Toxic Salbutamol, Ractopamine, And Clenbuterol In Pork Sample By High-Performance Liquid Chromatography - Uv Method, K. Yan, H. Zhang, W. Hui, H. Zhu, X. Li, F. Zhong, X. Tong, C. Chen Jul 2020

Rapid Screening Of Toxic Salbutamol, Ractopamine, And Clenbuterol In Pork Sample By High-Performance Liquid Chromatography - Uv Method, K. Yan, H. Zhang, W. Hui, H. Zhu, X. Li, F. Zhong, X. Tong, C. Chen

Journal of Food and Drug Analysis

A rapid and simple high-performance liquid chromatography–UV method was developed for the separation and quantification of salbutamol, ractopamine, and clenbuterol in pork. A mixture of acetonitrile–formic acid–ammonium acetate was used as the mobile phase to separate three β-agonists on a C18 column with gradient. The effects of the addition of formic acid and ammonium acetate to mobile phases on the separation of β-agonists were investigated. These additives can greatly improve the resolution and sensitivity. Under the optimized chromatographic condition, this separation does not need extra sample preparation. Complete baseline separation of three β-agonists was achieved in < 20 minutes; the linear range is 0.2–50 μg/L with a correlation coefficient R2 value of > 0.99. Excellent method reproducibility …

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Biochemical Characterization Of A Novel Antioxidant And Angiotensin I-Converting Enzyme Inhibitory Peptide From Struthio Camelus Egg White Protein Hydrolysis, A. Asoodeh, M. Homayouni-Tabrizi, H. Shabestarian, S. Emtenani, S. Emtenani Jul 2020

Biochemical Characterization Of A Novel Antioxidant And Angiotensin I-Converting Enzyme Inhibitory Peptide From Struthio Camelus Egg White Protein Hydrolysis, A. Asoodeh, M. Homayouni-Tabrizi, H. Shabestarian, S. Emtenani, S. Emtenani

Journal of Food and Drug Analysis

A peptide from ostrich (Struthio camelus) egg white protein hydrolysate (OEWPH) was purified, characterized, and its antioxidant and enzyme inhibitory properties were evaluated. The OEWPH was prepared using pepsin and pancreatin, and then fractionated using reversed-phase high performance liquid chromatography. The antioxidant activity of the WG-9 peptide was investigated based on its scavenging capacity for 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, 2,20-azinobis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS), superoxide (O2•-), hydroxyl (OH•-), and lipid peroxidation inhibition. The angiotensin-converting enzyme (ACE) inhibitory activity and kinetic parameters of the peptide were determined using N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine (FAPGG) as a substrate. Tandem mass spectrometry analysis of the purified peptide …

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Cholinesterase Inhibitory Activity And Chemical Constituents Of Stenochlaena Palustris Fronds At Two Different Stages Of Maturity, N.J.-Y. Chear, K.-Y. Khaw, V. Murugaiyah, C.-S. Lai Jul 2020

Cholinesterase Inhibitory Activity And Chemical Constituents Of Stenochlaena Palustris Fronds At Two Different Stages Of Maturity, N.J.-Y. Chear, K.-Y. Khaw, V. Murugaiyah, C.-S. Lai

Journal of Food and Drug Analysis

Stenochlaena palustris fronds are popular as a vegetable in Southeast Asia. The objectives of this study were to evaluate the anticholinesterase properties and phytochemical profiles of the young and mature fronds of this plant. Both types of fronds were found to have selective inhibitory effect against butyrylcholinesterase compared with acetylcholinesterase. However, different sets of compounds were responsible for their activity. In young fronds, an antibutyrylcholinesterase effect was observed in the hexane extract, which was comprised of a variety of aliphatic hydrocarbons, fatty acids, and phytosterols. In the mature fronds, inhibitory activity was observed in the methanol extract, which contained a …

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Characterizing Diversity Based On Nutritional And Bioactive Compositions Of Yam Germplasm (Dioscorea Spp.) Commonly Cultivated In China, Z.-G. Wu, W. Jiang, M. Nitin, X.-Q. Bao, S.-L. Chen, Z.-M. Tao Jul 2020

Characterizing Diversity Based On Nutritional And Bioactive Compositions Of Yam Germplasm (Dioscorea Spp.) Commonly Cultivated In China, Z.-G. Wu, W. Jiang, M. Nitin, X.-Q. Bao, S.-L. Chen, Z.-M. Tao

Journal of Food and Drug Analysis

Yams (Dioscorea spp.) are widely cultivated as edible resources and medical materials in China. Characterizing chemical compositions in yam germplasm is crucial to determine their diversity and suitability for food and medicine applications. In this study, a core germplasm containing 25 yam landraces was used to create an effective classification of usage by characterizing their nutritive and medicinal compositions. All studied landraces exhibited high contents of starch from 60.7% to 80.6% dry weight (DW), protein (6.3-12.2% DW), minerals (especially Mg 326.8-544.7 mg/kg DW), and essential amino acids. Allantoin and dioscin varied considerably, with values of 0.62-1.49% DW and 0.032-0.092% DW, …

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Determination Of Scutellarin In Breviscapine Preparations Using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy, Z. Jiang, J. Yang, Y. Jiao, W. Li, X. Chai, L. Zhang, M. Jiang, Y. Wang Jul 2020

Determination Of Scutellarin In Breviscapine Preparations Using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy, Z. Jiang, J. Yang, Y. Jiao, W. Li, X. Chai, L. Zhang, M. Jiang, Y. Wang

Journal of Food and Drug Analysis

The objective of the present study was to develop the selection criteria of proton signals for the determination of scutellarin using quantitative nuclear magnetic resonance (qNMR), which is the main bioactive compound in breviscapine preparations for the treatment of cerebrovascular disease. The methyl singlet signal of 3-(trimethylsilyl)propionic-2,2,3,3-d4 acid sodium salt was selected as the internal standard for quantification. The molar concentration of scutellarin was determined by employing different proton signals. To obtain optimum proton signals for the quantification, different combinations of proton signals were investigated according to two selection criteria: the recovery rate of qNMR method and quantitative results compared …

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Delphinidin Immobilized On Silver Nanoparticles For The Simultaneous Determination Of Ascorbic Acid, Noradrenalin, Uric Acid, And Tryptophan, N. Nasirizadeh, Z. Shekari, M. Dehghani, S. Makarem Jul 2020

Delphinidin Immobilized On Silver Nanoparticles For The Simultaneous Determination Of Ascorbic Acid, Noradrenalin, Uric Acid, And Tryptophan, N. Nasirizadeh, Z. Shekari, M. Dehghani, S. Makarem

Journal of Food and Drug Analysis

In the present study, the fabrication of a new modified electrode for electrocatalytic oxidation of noradrenalin, based on the delphinidin immobilized on silver nanoparticles modified glassy carbon electrode. Cyclic voltammetry was used to investigate the redox properties of this modified electrode. The surface charge transfer rate constant (ks) and the charge transfer coefficient (α) for the electron transfer between the glassy carbon electrode and the immobilized delphinidin were calculated. The differential pulse voltammetry exhibited two linear dynamic ranges and a detection limit of 0.40μM for noradrenalin determination. Moreover, the present electrode could separate the oxidation peak potentials of ascorbic acid, …

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Purification And Identification Of Anti-Inflammatory Peptides Derived From Simulated Gastrointestinal Digests Of Velvet Antler Protein (Cervus Elaphus Linnaeus), L. Zhao, X. Wang, X.-L. Zhang, Q.-F. Xie Jul 2020

Purification And Identification Of Anti-Inflammatory Peptides Derived From Simulated Gastrointestinal Digests Of Velvet Antler Protein (Cervus Elaphus Linnaeus), L. Zhao, X. Wang, X.-L. Zhang, Q.-F. Xie

Journal of Food and Drug Analysis

The objective of this study was to identify anti-inflammatory peptides from simulated gastrointestinal digest (pepsin-pancreatin hydrolysate) of velvet antler protein. The hydrolysate was purified using ultrafiltration and consecutive chromatographic methods. The anti-inflammatory activity of the purified fraction was evaluated by the inhibition of NO production in lipopolysaccharide-induced RAW 264.7 macrophages. Four anti-inflammatory peptides, VH (Val-His), LAN (Leu-Ala-Asn), AL (Ala-Leu), and IA (Ile-Ala), were identified by liquid chromatography/tandem mass spectrometry. Each of these peptides demonstrated a U-shaped dose-effect relationship. VH, LAN, AL and IA showed the strongest anti-inflammatory activities at 200 μg/mL, that is, 15.5%, 13.0%, 16.0% and 11.2% inhibition of …

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Effect Of An Avocado Oil-Enhanced Diet (Persea Americana) On Sucrose-Induced Insulin Resistance In Wistar Rats, Toro-Equihua M. Del, R. Velasco-Rodríguez, R. López-Ascencio, C. Vásquez Jul 2020

Effect Of An Avocado Oil-Enhanced Diet (Persea Americana) On Sucrose-Induced Insulin Resistance In Wistar Rats, Toro-Equihua M. Del, R. Velasco-Rodríguez, R. López-Ascencio, C. Vásquez

Journal of Food and Drug Analysis

A number of studies have been conducted to evaluate the effects of vegetable oils with varying percentages of monounsaturated and polyunsaturated fatty acids on insulin resistance. However, there is no report on the effect of avocado oil on this pathologic condition. The aim of this work was to evaluate the effect of avocado oil on sucrose-induced insulin resistance in Wistar rats. An experimental study was carried out on Wistar rats that were randomly assigned into six groups. Each group received a different diet over an 8-week period (n = 11 in each group): the control group was given a standard …

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Recent Progress On The Traditional Chinese Medicines That Regulate The Blood, H.-Y. Hung, T.-S. Wu Jul 2020

Recent Progress On The Traditional Chinese Medicines That Regulate The Blood, H.-Y. Hung, T.-S. Wu

Journal of Food and Drug Analysis

In traditional Chinese medicine, the herbs that regulate blood play a vital role. Here, nine herbs including Typhae Pollen, Notoginseng Root, Common Bletilla Tuber, India Madder Root and Rhizome, Chinese Arborvitae Twig, Lignum Dalbergiae Oderiferae, Chuanxiong Rhizoma, Corydalis Tuber, and Motherwort Herb were selected and reviewed for their recent studies on anti-tumor, anti-inflammatory and cardiovascular effects. Besides, the analytical methods developed to qualify or quantify the active compounds of the herbs are also summarized. Copyright © 2016, Food and Drug Administration, Taiwan. Published by Elsevier Taiwan LLC.

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Characterization Of Nine Polyphenols In Fruits Of Malus Pumila Mill By High-Performance Liquid Chromatography, L. Bai, S. Guo, Q. Liu, X. Cui, X. Zhang, L. Zhang, X. Yang, M. Hou, C.-T. Ho, N. Bai Jul 2020

Characterization Of Nine Polyphenols In Fruits Of Malus Pumila Mill By High-Performance Liquid Chromatography, L. Bai, S. Guo, Q. Liu, X. Cui, X. Zhang, L. Zhang, X. Yang, M. Hou, C.-T. Ho, N. Bai

Journal of Food and Drug Analysis

Polyphenols are important bioactive substances in apple. To explore the profiles of the nine representative polyphenols in this fruit, a high-performance liquid chromatography method has been established and validated. The validated method was successfully applied for the simultaneous characterization and quantification of these nine apple polyphenols in 11 apple extracts, which were obtained from six cultivars from Shaanxi Province, China. The results showed that only abscission of the Fuji apple sample was rich in the nine apple polyphenols, and the polyphenol contents of other samples varied. Although all the samples were collected in the same region, the contents of nine …

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Dietary Antioxidants And Their Indispensable Role In Periodontal Health, G. Kaur, R. Kathariya, S. Bansal, A. Singh, D. Shahakar Jul 2020

Dietary Antioxidants And Their Indispensable Role In Periodontal Health, G. Kaur, R. Kathariya, S. Bansal, A. Singh, D. Shahakar

Journal of Food and Drug Analysis

Periodontitis is an increasing area of interest due to its global prevalence. This inflammatory condition results due to the loss of the critical balance between the virulence factors produced by microorganisms and the inflammatory host response. A number of efforts have been made in the past to address this condition and regain periodontal health. Targeting the root cause by nonsurgical debridement has been considered the gold standard. However, research has shown the possible effects of nutrient deficiency and an imbalanced diet on the periodontium. Therefore, an effort toward the maintenance of optimal conditions as well as improvement of the oral …

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The Analytical Determination And Electrochemiluminescence Behavior Of Amoxicillin, L.-H. Shen, H.-N. Wang, P.-J. Chen, C.-X. Yu, Y.-D. Liang, C.-X. Zhang Jul 2020

The Analytical Determination And Electrochemiluminescence Behavior Of Amoxicillin, L.-H. Shen, H.-N. Wang, P.-J. Chen, C.-X. Yu, Y.-D. Liang, C.-X. Zhang

Journal of Food and Drug Analysis

A novel electrochemiluminescence (ECL) luminophor of amoxicillin was studied and found to generate ECL following the oxidation or reduction of amoxicillin. The amoxicillin oxidation state was also found to eliminate the reduction state, generating ECL. When solutions of amoxicillin were scanned between +1.5 V and -1.0 V with a graphite electrode in the presence of cetyltrimethyl ammonium bromide using KC1 as the supporting electrolyte, ECL emissions were observed at potentials of -0.7 V and +0.5 V. The ECL intensity at -0.7 V was enhanced by H2O2. Based on these findings, an ECL method for the determination of the amoxicillin concentration …

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Determination Of The Levels Of Two Types Of Neurotransmitter And The Anti-Migraine Effects Of Different Dose-Ratios Of Ligusticum Chuanxiong And Gastrodia Elata, Q. Wang, L. Shen, S.-Y. Ma, M.-W. Chen, X. Lin, Y.-L. Hong, Y. Feng Jul 2020

Determination Of The Levels Of Two Types Of Neurotransmitter And The Anti-Migraine Effects Of Different Dose-Ratios Of Ligusticum Chuanxiong And Gastrodia Elata, Q. Wang, L. Shen, S.-Y. Ma, M.-W. Chen, X. Lin, Y.-L. Hong, Y. Feng

Journal of Food and Drug Analysis

Ligusticum chuanxiong (LC)-Gastrodia elata (GE) compatibility is widely used in the clinic for the treatment of migraine. It has been shown that the changes of neurotransmitters in the central nervous system are closely related to the pathogenesis of migraine; whether LC-GE compatibility might affect the neurotransmitters in migraine rats has not yet been studied. In this study, high performance liquid chromatography-fluorescence detector methods for quantification of serotonin (5-hydroxytryptamine, 5-HT) and excitatory amino acids (EAAs) in rat brain were developed. The 5-HT was measured directly, while EAAs were determined by using dansyl chloride as precolumn derivative reagent. The validation of the …

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Chemopreventive Effect Of Myrtenal On Bacterial Enzyme Activity And The Development Of 1,2-Dimethyl Hydrazine-Induced Aberrant Crypt Foci In Wistar Rats, L.K. Booupathy, S. Venkatachalam, N. Natarajan, R. Thamaraiselvan, M. Arumugam, Periyasamy B. Maruthaiveeran Jul 2020

Chemopreventive Effect Of Myrtenal On Bacterial Enzyme Activity And The Development Of 1,2-Dimethyl Hydrazine-Induced Aberrant Crypt Foci In Wistar Rats, L.K. Booupathy, S. Venkatachalam, N. Natarajan, R. Thamaraiselvan, M. Arumugam, Periyasamy B. Maruthaiveeran

Journal of Food and Drug Analysis

Colon cancer remains as a serious health problem around the world despite advances in diagnosis and treatment. Dietary fibers are considered to reduce the risk of colon cancer as they are converted to short chain fatty acids by the presence of anaerobic bacteria in the intestine, but imbalanced diet and high fat consumption may promote tumor formation at different sites, including the large bowel via increased bacterial enzymes activity. The present study was conducted to characterize the inhibitory action of myrtenal on bacterial enzymes and aberrant crypt foci (ACF). Experimental colon carcinogenesis induced by 1,2-dimethylhydrazine is histologically, morphologically, and anatomically …

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High Performance Liquid Chromatography (Hplc) Fingerprints And Primary Structure Identification Of Corn Peptides By Hplc-Diode Array Detection And Hplc-Electrospray Ionization Tandem Mass Spectrometry, C. Wang, H. He, J.-L. Zhang, X. Li, Z.-L. Ma Jul 2020

High Performance Liquid Chromatography (Hplc) Fingerprints And Primary Structure Identification Of Corn Peptides By Hplc-Diode Array Detection And Hplc-Electrospray Ionization Tandem Mass Spectrometry, C. Wang, H. He, J.-L. Zhang, X. Li, Z.-L. Ma

Journal of Food and Drug Analysis

Corn peptides (CPs) are reported to have many biological functions, such as facilitating alcohol metabolism, antioxidation, antitumor, antihypertension, and hepatoprotection. To develop a method for quality control, the high-performance liquid chromatography (HPLC) system was applied. Twenty-eight common peaks were found in all the CPs of corn samples from Enshi, China, based on which, a fingerprinting chromatogram was established for use in quality control in future research. Subsequently, the major chemical constituents of these common peaks were identified respectively using the HPLC-diode-array detection electrospray ionization tandem mass spectrometry (DAD-ESI-MS/MS) system, and 48 peptide fractions were determined ultimately. This was the first …

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Determination Of Pb (Lead), Cd (Cadmium), Cr (Chromium), Cu (Copper), And Ni (Nickel) In Chinese Tea With High-Resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry, W.-S. Zhong, T. Ren, L.-J. Zhao Jul 2020

Determination Of Pb (Lead), Cd (Cadmium), Cr (Chromium), Cu (Copper), And Ni (Nickel) In Chinese Tea With High-Resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry, W.-S. Zhong, T. Ren, L.-J. Zhao

Journal of Food and Drug Analysis

The contents of lead, cadmium, chromium, copper, and nickel were determined in 25 tea samples from China, including green, yellow, white, oolong, black, Pu'er, and jasmine tea products, using high-resolution continuum source graphite furnace atomic absorption spectrometry. The methods used for sample preparation, digestion, and quantificational analysis were established, generating satisfactory analytical precisions (represented by relative standard deviations ranging from 0.6% to 2.5%) and recoveries (98.91-101.32%). The lead contents in tea leaves were 0.48-10.57 mg/kg, and 80% of these values were below the maximum values stated by the guidelines in China. The contents of cadmium and chromium ranged from 0.01 …

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Rapid Confirmatory Analysis Of Avermectin Residues In Milk By Liquid Chromatography Tandem Mass Spectrometry, N. Ozdemir, T. Kahraman Jul 2020

Rapid Confirmatory Analysis Of Avermectin Residues In Milk By Liquid Chromatography Tandem Mass Spectrometry, N. Ozdemir, T. Kahraman

Journal of Food and Drug Analysis

Our study developed a quick method for confirmatory analysis of avermectins (abamectin B1a, doramectin, ivermectin B1a, eprinomectin B1a, and moxidectin) in bovine milk according to the European Commission Decision 2002/657/EC requirements. Avermectins were liquid-liquid extracted with acetonitrile, followed by an evaporation step, and then analyzed by liquid chromatography/electrospray ionization tandem mass spectrometry in the negative ion mode. An in-house method validation was performed and the data reported on specificity, linearity, recovery, limit of detection, limit of quantitation, decision limit, and detection capability. The advantage of this method is that low levels of avermectins are detectable and quantitatively confirmed at a …

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Fabrication Of A Novel Electrochemical Sensor For Determination Of Hydrogen Peroxide In Different Fruit Juice Samples, N. Nasirizadeh, Z. Shekari, A. Nazari, M. Tabatabaee Jul 2020

Fabrication Of A Novel Electrochemical Sensor For Determination Of Hydrogen Peroxide In Different Fruit Juice Samples, N. Nasirizadeh, Z. Shekari, A. Nazari, M. Tabatabaee

Journal of Food and Drug Analysis

A new hydrogen peroxide (H2O2) sensor is fabricated based on a multiwalled carbon nanotube-modified glassy carbon electrode (MWCNT-GCE) and reactive blue 19 (RB). The charge transfer coefficient, α, and the charge transfer rate constant, ks, of RB adsorbed on MWCNT-GCE were calculated and found to be 0.44 ± 0.01 Hz and 1.9 ± 0.05 Hz, respectively. The catalysis of the electroreduction of H2O2 by RB-MWCNT-GCE is described. The RB-MWCNT-GCE shows a dramatic increase in the peak current and a decrease in the overvoltage of H2O2 electroreduction in comparison with that seen at an RB modified GCE, MWCNT modified GCE, and …

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Nanomaterial-Based Sensors For Detection Of Foodborne Bacterial Pathogens And Toxins As Well As Pork Adulteration In Meat Products, Inbaraj B. Stephen, B.H. Chen Jul 2020

Nanomaterial-Based Sensors For Detection Of Foodborne Bacterial Pathogens And Toxins As Well As Pork Adulteration In Meat Products, Inbaraj B. Stephen, B.H. Chen

Journal of Food and Drug Analysis

Food safety draws considerable attention in the modern pace of the world owing to rapid-changing food recipes and food habits. Foodborne illnesses associated with pathogens, toxins, and other contaminants pose serious threat to human health. Besides, a large amount of money is spent on both analyses and control measures, which causes significant loss to the food industry. Conventional detection methods for bacterial pathogens and toxins are time consuming and laborious, requiring certain sophisticated instruments and trained personnel. In recent years, nanotechnology has emerged as a promising field for solving food safety issues in terms of detecting contaminants, enabling controlled release …

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Pacific Oyster-Derived Polysaccharides Attenuate Allergen-Induced Intestinal Inflammation In A Murine Model Of Food Allergy, C.-H. Cheng, H.-Y. Wu, C.-F. Wu, T.-R. Jan Jul 2020

Pacific Oyster-Derived Polysaccharides Attenuate Allergen-Induced Intestinal Inflammation In A Murine Model Of Food Allergy, C.-H. Cheng, H.-Y. Wu, C.-F. Wu, T.-R. Jan

Journal of Food and Drug Analysis

Oyster-derived polysaccharides (OPS) have been shown to modulate the T helper (Th)1/Th2 immunobalance toward the Th1-dominant direction in antigen-primed splenocytes. In the present study, we hypothesized that OPS might attenuate intestinal inflammation associated with food allergy, a Th2-dominant immune disorder. BALB/c mice were sensitized twice with ovalbumin (OVA) absorbed to alum and then repeatedly challenged with intragastric OVA to induce intestinal allergic responses. The mice were administered by gavage with OPS and/or vehicle (distilled water) once/d during the two sensitization phases, and once every other day during the challenge phase. Administration with OPS attenuated OVA challenge-elicited diarrhea, and the infiltration …

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Determination Of Histamine In Milkfish Stick Implicated In Food-Borne Poisoning, Y.-C. Lee, H.-F. Kung, C.-H. Wu, H.-M. Hsu, H.-C. Chen, T.-C. Huang, Y.-H. Tsai Jul 2020

Determination Of Histamine In Milkfish Stick Implicated In Food-Borne Poisoning, Y.-C. Lee, H.-F. Kung, C.-H. Wu, H.-M. Hsu, H.-C. Chen, T.-C. Huang, Y.-H. Tsai

Journal of Food and Drug Analysis

An incident of food-borne poisoning causing illness in 37 victims due to ingestion of fried fish sticks occurred in September 2014, in Tainan city, southern Taiwan. Leftovers of the victims' fried fish sticks and 16 other raw fish stick samples from retail stores were collected and tested to determine the occurrence of histamine and histamine-forming bacteria. Two suspected fried fish samples contained 86.6 mg/100 g and 235.0 mg/100 g histamine; levels that are greater than the potential hazard action level (50 mg/100 g) in most illness cases. Given the allergy-like symptoms of the victims and the high histamine content in …

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Isolation Of Eugenyl Β-Primeveroside From Camellia Sasanqua And Its Anticancer Activity In Pc3 Prostate Cancer Cells, C.-C. Wang, C.-T. Ho, S.-C. Lee, T.-D. Way Jul 2020

Isolation Of Eugenyl Β-Primeveroside From Camellia Sasanqua And Its Anticancer Activity In Pc3 Prostate Cancer Cells, C.-C. Wang, C.-T. Ho, S.-C. Lee, T.-D. Way

Journal of Food and Drug Analysis

Most studies of tea trees have focused on their ornamental properties, there are fewer published studies on their medical values. The purpose of this study was to compare the chemical constituents and the biological potential of the water extract of leaves in eight species of Camellia including Camellia sinensis. Among eight Camellia species, Camellia sasanqua showed potent anticancer activities in prostate cancer PC3 cells. In addition to catechins, the major component, eugenyl β-primeveroside was detected in C. sasanqua. Eugenyl β-primeveroside blocked the progression of cell cycle at G1 phase by inducing p53 expression and further upregulating p21 expression. Moreover, eugenyl …

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Chemical Quality Evaluation Of Antrodia Cinnamomea Fruiting Bodies Using Phytomics Similarity Index Analysis, C.-H. Chung, S.-C. Yeh, H.-C. Tseng, M.-L. Siu, K.-T. Lee Jul 2020

Chemical Quality Evaluation Of Antrodia Cinnamomea Fruiting Bodies Using Phytomics Similarity Index Analysis, C.-H. Chung, S.-C. Yeh, H.-C. Tseng, M.-L. Siu, K.-T. Lee

Journal of Food and Drug Analysis

The fruiting body of Antrodia cinnamomea is used as a medicinal mushroom in Taiwan and is found on the inner cavity of the endemic species Cinnamomum kanehirai. In this study, phytomics similarity index (PSI) analysis was employed for the chemical quality evaluation of the A. cinnamomea fruiting bodies from different strains, and grown on various substrates. The results indicated that the different types of A. cinnamomea fruiting bodies contain eight index compounds, and that it was difficult to discriminate between them solely on the basis of those index compounds. In our research, we used PSI scores to assess the metabolite …

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Myrciaria Cauliflora Extracts Attenuate Diabetic Nephropathy Involving The Ras Signaling Pathway In Streptozotocin/Nicotinamide Mice On A High Fat Diet, C.-C. Wu, C.-N. Hung, Y.-C. Shin, C.-J. Wang, H.-P. Huang Jul 2020

Myrciaria Cauliflora Extracts Attenuate Diabetic Nephropathy Involving The Ras Signaling Pathway In Streptozotocin/Nicotinamide Mice On A High Fat Diet, C.-C. Wu, C.-N. Hung, Y.-C. Shin, C.-J. Wang, H.-P. Huang

Journal of Food and Drug Analysis

Diabetic nephropathy (DN) is a major cause of end-stage renal disease and its mortality is continuously increasing worldwide. Previous studies indicate that reactive oxygen species play an important role in high glucose-induced renal injury. Myrciaria cauliflora has been reported as a functional food rich in anthocyanins possessing anti-oxidative and anti-inflammatory properties. This study examined whether M. cauliflora extracts (MCE) can attenuate diabetic nephropathy progression in type 2 diabetes mellitus mice. First, the composition of the anthocyanins and polyphenols of MCE were determined by high-performance liquid chromatography and spectrophotometry. One hundred mg/kg of streptozotocin and 240 mg/kg nicotinamide were administered to …

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Antioxidant And Antidiabetic Activities Of 11 Herbal Plants From Hyrcania Region, Iran, H. Dehghan, Y. Sarrafi, P. Salehi Jul 2020

Antioxidant And Antidiabetic Activities Of 11 Herbal Plants From Hyrcania Region, Iran, H. Dehghan, Y. Sarrafi, P. Salehi

Journal of Food and Drug Analysis

In the present study, 2,2-diphenyl-1-picrylhydrazyl radical scavenging, α-amylase and α-glucosidase inhibition activities, and total phenolic contents of n-hexane, ethyl acetate, and methanol extracts of various parts of Allium paradoxum, Buxus hyrcana, Convolvulus persicus, Eryngium caucasicum, Heracleum persicum, Pimpinella affinis, Parrotia persica, Primula heterochroma, Pyrus boissieriana, Ruscus hyrcanus, and Smilax excelsa were investigated. These plants, which mostly serve as food flavoring, were collected from Hyrcania region, Sari, Iran. Some extracts of H. persicum, S. excels, P. boissieriana, P. persica, and P. heterochroma exhibited significant antidiabetic activities in α-amylase and α-glucosidase assays, more effective than acarbose (concentrations that cause 50% inhibition = …

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