Human and Clinical Nutrition Commons^™

Reduced Mitochondrial Dna And Oxphos Protein Content In Skeletal Muscle Of Children With Cerebral Palsy, Ferdinand Von Walden, Ivan J. Vechetti Jr, Davis Englund, Vandre C. Figueiredo, Rodrigo Fernandez-Gonzalo, Kevin Murach, Jessica Pingel, John J. Mccarthy, Per Stal, Eva Ponten

Department of Nutrition and Health Sciences: Faculty Publications

AIM To provide a detailed gene and protein expression analysis related to mitochondrial biogenesis and assess mitochondrial content in skeletal muscle of children with cerebral palsy (CP). METHOD Biceps brachii muscle samples were collected from 19 children with CP (mean [SD] age 15y 4mo [2y 6mo], range 9–18y, 16 males, three females) and 10 typically developing comparison children (mean [SD] age 15y [4y], range 7–21y, eight males, two females). Gene expression (quantitative reverse transcription polymerase chain reaction [PCR]), mitochondrial DNA (mtDNA) to genomic DNA ratio (quantitative PCR), and protein abundance (western blotting) were analyzed. Microarray data sets (CP/aging/bed rest) were …

Factors Associated With Lifestyle Modification For Type 2 Diabetes Self-Management And Prevention, Leigh Anne Koonmen

Theses and Dissertations--Nursing

Diabetes is the seventh leading cause of death in the United States, affecting roughly 13% of U.S. adults aged 18 years or older. Type 2 diabetes accounts for 90-95% of all diabetes cases and is characterized by the progressive development of insulin resistance leading to sustained elevated blood glucose levels. Management of type 2 diabetes includes risk-reduction strategies and continuous medical care to prevent the development of complications.

Lifestyle is a major contributing factor to morbidity and mortality rates in the United States. Preventative health behaviors, such as engaging in physical activity, maintaining a healthy weight, and following a healthy …

Stunting And Combined Overweight With Stunting Among Schoolchildren In Kuwait: Trends Over A 13-Year Period, Abdullah Al-Taiar, Nawal Alqaoud, Reem Sharaf Alddin, Faheema Alanezi, Monica Subhakaran, Anne Dumadag, Ahmed N. Albatineh

Community & Environmental Health Faculty Publications

Objectives: This study aimed to investigate the sex- and age-specific trends of stunting and combined overweight with stunting among schoolchildren over a 13-year period in Kuwait. Subjects and Methods: The Kuwait Nutrition Surveillance System objectively measured the height of 172,573 schoolchildren (5–19 years) over a 13-year period (2007–2019). Data on gender and date of birth were extracted from school records. Stunting was defined as height 2 standard deviations (SD) below the World Health Organization growth reference median. Logistic regression models were used to examine the trends of stunting over the study period while stratifying by gender. Results: In males, the …

Exploring The Relationships Between Cultural Values And Diet Patterns Among Mexican And Cuban Immigrants In Kentucky, Nasreen Omran

Theses and Dissertations--Nutrition and Food Systems

The number of Latinx in the U.S. is expected to grow to about 28 percent of the population by the year 2060. As the number of Latinx increases in the U.S. it is important to understand how cultural beliefs influence dietary behaviors as Latinx are disproportionately affected by diet related disease such as diabetes mellitus, cancer, and cardiovascular disease. The aim of this secondary data analysis is to examine the relationship between family values, gender roles, and religious values on diet patterns in adult Mexican and Cuban immigrants in Kentucky utilizing the Mexican American Cultural Values Scale. The study findings …

Physician Knowledge, Attitudes, And Behaviors Towards Registered Dietitian Nutritionists, Amy Motley Jones

UNF Graduate Theses and Dissertations

Diet is increasingly linked with overall quality of life, and a healthy diet is now being considered one of the cornerstones of preventative care. Physicians rely on Registered Dietitian Nutritionists (RDNs) as most doctors lack the nutrition knowledge to properly treat their patients, especially during their residency. Little published information exists on the specific collaboration of RDNs and resident physicians. This study aimed to determine whether mentoring with an RDN increased physician nutrition knowledge, increased consults to RDNs, and whether physician attitudes improved regarding their understanding of the role of the RDN in healthcare. Knowledge or attitude alone are not …

The Effect Of Whey Protein Supplementation At Breakfast On Tryptophan Levels, Food Intake, And Mood In Postmenopausal Women In A 16-Week Randomized Controlled Trial, Danielle L. Lamont, Jamie I. Baum

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Whey protein isolate supplementation has been recognized as having potential for regulating appetite, thereby potentially improving mood and food intake. The objectives of this project were to 1) analyze the effects of high-quality whey protein intake on overall diet and 2) identify and examine a correlation between tryptophan levels and mood regulation. This research was conducted using a randomized experimental design. A total of 13 postmenopausal women (12+ months after last reported menstrual cycle) were recruited and allocated to one of two dietary intervention (DI) groups: 1) control (maintain current lifestyle; CON; n = 6), and 2) whey protein isolate …

Serving Refugees In A Pandemic: Insights From Yazidis In The Midwest, Falah N. Rashoka M.S, Megan S. Kelley, Marc A. Garcia

Department of Nutrition and Health Sciences: Faculty Publications

There is a critical need for research to examine factors that hinder or facilitate access to healthcare in the context of COVID-19. The coronavirus pandemic has exacerbated barriers to healthcare for marginalized communities globally, leaving many without access to needed health services. Resettled refugees, in particular, must grapple with added challenges to locating and obtaining culturally appropriate healthcare services.

Recent focus groups shed light on the experiences of Yazidi refugees in the U.S. Midwest during COVID-19. Yazidis are a historically persecuted religious and ethnic minority group from northern Iraq (Kizilhan, 2017). Many Yazidis migrated to the U.S. on Special Immigrant …

Differential Effects Of Whole Red Raspberry Polyphenols And Their Gut Metabolite Urolithin A On Neuroinflammation In Bv-2 Microglia, Ashley Mulcahy Toney, Mahaa Albusharif, Duncan Works, Luke Polenz, Stacie Schlange, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Whole red raspberry polyphenols (RRW), including ellagic acid, and their gut-derived metabolite, urolithin A (UroA), attenuate inflammation and confer health benefits. Although results from recent studies indicate that polyphenols and UroA also provide neuroprotective effects, these compounds differ in their bioavailability and may, therefore, have unique effects on limiting neuroinflammation. Accordingly, we aimed to compare the neuroprotective effects of RRW and UroA on BV-2 microglia under both 3 h and 12 and 24 h inflammatory conditions. In inflammation induced by lipopolysaccharide (LPS) and ATP stimulation after 3 h, RRW and UroA suppressed pro- inflammatory cytokine gene expression and regulated the …

Covid-19 Contagion Among Communities With Limited English Proficiency: Lesson From Volunteerism, Falah N. Rashoka M.S

Department of Nutrition and Health Sciences: Faculty Publications

The COVID-19 affects all communities in the United States, but its impact differs from one community to another. Undoubtedly, the vulnerable populations are more impacted than others, especially refugees and immigrants. This study seeks to understand the impact of COVID-19 on marginalized communities and the need to communicate health-related information equally. A lesson learned from observation during an ongoing pandemic, including what I learned through my volunteer work between mid-March and August 2020. The study finds that neighbors with limited English Proficiency (LEP) and limited education could quickly transfer the COVID-19 virus to another neighbor with high income and well-educated. …

Essential Role Of Systemic Iron Mobilization And Redistribution For Adaptive Thermogenesis Through Hif2-Α/Hepcidin Axis, Jin-Seon Yook, Mikyoung You, Jiyoung Kim, University Of Nebraska-Lincoln, Rong Fan, Bhanwar Lal Puniya, Tomáš Helikar, Sophie Vaulont, Jean-Christophe Deschemin, Meshail Oklar, Liwei Xie, Manik C. Ghosh, Tracey A. Rouault, Jaekwon Lee, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Iron is an essential biometal, but is toxic if it exists in excess. Therefore, iron content is tightly regulated at cellular and systemic levels to meet metabolic demands but to avoid toxicity. We have recently reported that adaptive thermogenesis, a critical metabolic pathway to maintain whole-body energy homeostasis, is an irondemanding process for rapid biogenesis of mitochondria. However, little information is available on iron mobilization from storage sites to thermogenic fat. This study aimed to determine the iron-regulatory network that underlies beige adipogenesis. We hypothesized that thermogenic stimulus initiates the signaling interplay between adipocyte iron demands and systemic iron liberation, …

The Relationship Between Eating Disorders, Weight Control Methods, And Body Satisfaction In Elite Female Runners Competing At The 2020 U.S. Olympic Marathon Trials, Sophia Elizabeth Berg

All Master's Theses

The prevalence of eating disorders in athletes is higher than in the general population. Various training styles, weight periodization, and presence of eating disorder (ED) may affect energy availability. This study investigated the relationship between lifetime prevalence of ED with training, body satisfaction, and weight-control methods among elite female endurance athletes. Female runners who participated in the 2020 U.S. Olympic Team Trials Marathon completed an online questionnaire examining training volume, weight-control methods, and self-reported current or past ED. Questions 1-19 were analyzed for this investigation. Participants were grouped according to responses on presence of ED. Thirty-two percent of participants reported …

Evaluation Of A Telenutrition Weight Loss Intervention Among Middle-Aged And Older Men In Appalachia, Afnan Majed Alamoudi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Obesity rates among middle-aged and older men in WV are among the highest in the nation. Understanding baseline and intervention factors contributing to losing clinically significant weight are essential to developing effective interventions in target groups. Thus, the purpose of this study is to determine factors associated with losing ≥ 5% of baseline weight among participants of a 12-week pilot randomized controlled telenutrition trial for middle-aged and older men in WV. The study analyzed data from 56 participants who completed the trial. Participants were classified as losing ≥ 5 % or < 5 % of baseline body weight. Diet quality was assessed using 4-day diet records and the Healthy Eating Index (HEI)-2015. Baseline factors and behavioral strategies (i.e., self-monitoring, self-efficacy, and social support) were assessed via survey. Inverse prediction analysis demonstrated that participants who lost ≥ 3.5% of baseline weight at 6 weeks were at least 75% likely to lose ≥ 5% weight at 12 weeks. Predictive models were developed using stepwise logistic regression to assess multiple predictors of losing ≥ 5% of baseline weight at 12 weeks and ≥ 3.5% of baseline at 6 weeks. Weight loss at 6 weeks was a strong predictor of weight loss at 12 weeks, in addition to previous weight loss attempts and weekly self-weight-monitoring (p

Impact Of Physical Activity And Cardiorespiratory Fitness On Vascular Homeostasis In Premenopausal Women Consuming A Westernized High-Fat Meal, Lauren N. Pedersen

Theses and Dissertations

A large percentage of adults in industrialized nations consume a Westernized dietary pattern, which contributes to fasting dyslipidemia and increased risk for atherosclerotic cardiovascular disease. Evidence suggests that a single Westernized meal containing high saturated fat may induce alterations in blood lipids as well as disturb multiple factors regulating peripheral vascular homeostasis, including innate immune cell function, oxidative stress, and vascular function. Conversely, participation in acute and chronic exercise may beneficially impact an individual’s postprandial response. Therefore, this dissertation contains three manuscripts seeking to describe how acute exercise, cardiorespiratory fitness, and physical activity level impact the lipemic and vascular homeostatic …

Effect Of Whole Fruit Based Anthocyanins On Systemic Inflammation, Oxidative Stress, And Waist Circumference In Women, Anastasiya Yudinova

Cal Poly Humboldt theses and projects

Cardiometabolic disease (CMD) remains the leading cause of death nationally. Intra-abdominal fat (IAF) is one of the primary risk factors for CMD. Women are particularly vulnerable to developing CMD due to hormonal changes during and after menopause that increase IAF. Excess IAF has deleterious effects on the body, increasing systemic inflammation and oxidative stress, leading to CMD. This systematic review and meta-analyses examined current research related to consumption of whole foods high in anthocyanins, their impact on oxidative stress and inflammation, and the medium and amount of anthocyanin delivery that yields the most benefits to women at risk for CMD. …

Parents' Attitudes And Beliefs Towards Dietary Behaviors Of Children With Autism Aged 5-13 Years, Subashree Narayanan

UNF Graduate Theses and Dissertations

Autism is a neurodevelopmental disability that may affect nutritional management of children with autism. Parent’s attitudes and their behavior towards healthy eating reflects on the child’s eating habits and thus, their nutritional health. This study aimed to describe the diet quality of children with autism using the Healthy Eating Index (HEI) scores. It also aimed to assess the relationship between parent’s perceived barriers and self-efficacy and children’s dietary behavior and dietary intake (age 5-13 years). The relationship was assessed using 2 questionnaires, Nutrition and Health Awareness and BAMBI questionnaire for parent’s attitudes and beliefs and dietary behavior, respectively. Dietary intake …

A Descriptive Analysis Of Intuitive Eating On The Uni Campus, Natalee Jeanne Lyons

Honors Program Theses

Over the course of this project, we will send out a cross-sectional survey to undergraduate students living on UNI’s campus. Included in the survey are questions regarding nutritional campus climate, student’s food preferences and eating habits, as well as the complete second edition of the Intuitive Eating Scale (Tylka & Kroon Van Diest, 2013).

This survey will then be analyzed utilizing SPSS software to draw conclusions regarding this target population (IBM Corp, 2016). Upon completion of this data analysis, our research 2 team hopes to address the following questions: What factors influence the eating behaviors of college students living on …

Vulnerable And Resilient Phenotypes In A Mouse Model Of Anorexia Nervosa, Jeff A. Beeler, Devry Mourra, Roseanna M. Zanca, Abigail Kalmbach, Celia Gellman, Benjamin Y. Klein, Rebecca Ravenelle, Peter Serrano, Holly Moore, Stephen Rayport, Susana Mingote, Nesha Burghard

Advanced Science Research Center

Background

Increased physical activity is a common feature of anorexia nervosa (AN). Although high activity levels are associated with greater risk of developing AN, particularly when combined with dieting, most individuals who diet and exercise maintain a healthy body weight. It is unclear why some individuals develop AN while most do not. A rodent model of resilience and vulnerability to AN would be valuable to research. Dopamine, which is believed to play a crucial role in AN, regulates both reward and activity and may modulate vulnerability.

Methods

Adolescent and young adult female C57BL/6N mice were tested in the activity-based anorexia …

Effects Of Consuming Sugar-Sweetened Beverages For 2 Weeks On 24-H Circulating Leptin Profiles, Ad Libitum Food Intake And Body Weight In Young Adults, Desiree M. Sigala, Adrianne M. Widaman, Bettina Hieronimus, Marinelle V. Nunez, Vivien Lee, Yanet Benyam, Andrew A. Bremer, Valentina Medici, Peter J. Havel, Kimber L. Stanhope, Nancy L. Keim

Faculty Research, Scholarly, and Creative Activity

Sugar-sweetened beverage (sugar-SB) consumption is associated with body weight gain. We investigated whether the changes of (Δ) circulating leptin contribute to weight gain and ad libitum food intake in young adults consuming sugar-SB for two weeks. In a parallel, double-blinded, intervention study, participants (n = 131; BMI 18–35 kg/m2; 18–40 years) consumed three beverages/day containing aspartame or 25% energy requirement as glucose, fructose, high fructose corn syrup (HFCS) or sucrose (n = 23–28/group). Body weight, ad libitum food intake and 24-h leptin area under the curve (AUC) were assessed at Week 0 and at the end of Week …

Brain Α-Tocopherol Concentration Is Inversely Associated With Neurofibrillary Tangle Counts In Brain Regions Affected In Earlier Braak Stages: A Cross-Sectional Finding In The Oldest Old, J. Tanprasertsuk, T.M. Scott, M.A. Johnson, L.W. Poon, P.T. Nelson, A. Davey, J.L. Woodard, R. Vishwanathan, A.K. Barbey, K. Barger, X.-D. Wang, E.J. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Objectives: Higher vitamin E status has been associated with lower risk of Alzheimer’s disease (AD). However, evidence of the association of vitamin E concentration in neural tissue with AD pathologies is limited. Design: The cross-sectional relationship between the human brain concentrations of α- and γ-tocopherol and the severity of AD pathologies – neurofibrillary tangle (NFT) and neuritic plaque (NP) – was investigated. Setting & Participants: Brains from 43 centenarians (≥ 98 years at death) enrolled in the Phase III of the Georgia Centenarian Study were collected at autopsy. Measurements: Brain α- and γ-tocopherol concentrations (previously reported) …

Holidays And Healthy Choices, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Objectives:

Healthy holiday eating

Incorporating physical activity into the holiday season

Budget friendly healthy holiday ideas

Translating Evidence-Based Guidelines Into Practice—Are We Getting It Right? A Multi-Centre Prospective International Audit Of Nutrition Care In Patients With Foregut Tumors (Inform), Merran Findlay, Judith D. Bauer, Rupinder Dhaliwal, Marian De Van Der Schueren, Alessandro Laviano, Adrianne Widaman, Lisa Martin, Andrew G. Day, Leah M. Gramlich

Faculty Research, Scholarly, and Creative Activity

Malnutrition is highly prevalent in patients with foregut tumors comprising head and neck (HNC) and esophageal (EC) cancers, negatively impacting outcomes. International evidence-based guidelines (EBGs) for nutrition care exist; however, translation of research evidence into practice commonly presents considerable challenges and consequently lags. This study aimed to describe and evaluate current international nutrition care practices compared with the best-available evidence for patients with foregut tumors who are at high risk of malnutrition. A multi-centre prospective cohort study enrolled 170 patients commencing treatment of curative intent for HNC (n = 119) or EC (n = 51) in 11 cancer …

Diet And Successful Aging, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Learning Objectives:

Define successful aging

Understand the components of successful aging

Learn diets and dietary patterns for successful aging

Physical activity and successful aging

Relationship Between Disordered Eating Risk & Body Image Dissatisfaction Of Spirit Squad Members, Sarah Abdul Albandar

Graduate Theses

Background: Investigations into body image and disordered eating habits among aesthetic sports has shown that these athletes face pressures to be thin and to be a certain body type for their sport.

Research aim/question(s): This study sought to determine if disordered eating habits and body dissatisfaction were prevalent within this population, whether or not there is a relationship between body image and disordered eating, and to determine the current research gap on body image and disordered eating among cheerleaders and dancers.

Materials and Methods: Participants were 23 females including cheerleaders and dancers on the Spirit Squad as well as dance …

Dietary Regulation Of Successful Aging, Aubree L. Hawley

Graduate Theses and Dissertations

The current growth of the older population is unprecedented in U.S. history. Chronic disease and functional limitation commonly develop prior to old age, leading to prolonged physical disability and decreased well-being. The development of chronic disease and loss of independence is associated with lean body mass (LBM) loss and fat mass gain beginning in middle age. Therefore, it is important to identify modifiable factors to mitigate deleterious shifts in body composition to promote successful aging (SA). The concept of SA is associated with longevity, the absence of disease and disability, and subjective components of well-being, however, an operational definition has …

Vegetarian And Vegan Eating Patterns, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Objectives:

Different types of vegetarian diets.

Identifying challenges vegetarians may experience

Protein complementation

Compare and contrast the dietary recommendations

Referring Patients With Type 2 Diabetes To A Registered Dietitian Nutritionist In New Mexico, Rebecca A. Lamoreux

Individual, Family, and Community Education ETDs

Prevalence of Type 2 Diabetes (T2DM) in New Mexico (NM) has steadily increased to 12.5% in 2019.¹Registered Dietitian Nutritionists (RDNs) play a critical role in the T2DM healthcare team. A web-based survey was distributed to NM clinicians [Medical Doctors (MD), Doctors of Osteopathic Medicine (DO), Certified Nurse Practitioners (CNP), and Certified Physician Assistants (PA-C)] investigating barriers preventing referral of patients with T2DM to an RDN.

In total, 132 clinicians completed the survey (average age=52 years; 54.5% CNPs, 32.6% MDs, 9.1% PA-Cs, 3.9% DOs; 44% female). Most (67.4%) did not have an RDN employed in their practice. The majority …

Diet And Exercise: What To Eat And When, Brittany Allman

Diet, Food, Exercise, and Nutrition (D-FEND)

Learning Objectives:

Define nutrient timing

Understand the importance of nutrient timing

Understand the different types of carbohydrates

Understand how eating patterns can affect sleep

Health Benefits Of Berries, Luke Howard

Diet, Food, Exercise, and Nutrition (D-FEND)

Berry phytonutrients

Free radicals and antioxidants

Health benefits beyond antioxidant activity

Bioavailability of phytonutrients

Nutrition, Exercise, And Mental Health, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Understand factors that can impact our mental health

Understand how certain foods can benefit our mental health

Understand how exercise can benefit our mental health

Body Weight Prediction Model Using Mid Upper Arm Circumferences And Knee Height In Adult, Katherina Katherina, Trini Sudiarti

Indonesian Journal of Public Health Nutrition (IJPHN)

Bodyweight is one of the most common anthropometric components to determin e a prescription for diet and drugs. However, this way proved to be a challenge for individuals who are unconscious and or have disabilities. The present study aims to derive a simple equation to estimate the bodyweight of adults in Jakarta by using a cross-sectional study on data taken with simple random sample method. Measurements of body weight (BW), the mid-upper arm circumference (MUAC), and the knee height (KH) were done in 164 adults in South Jakarta in May 2017. The resulting equation, which is derived by multi linear …