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Molecular and Cellular Neuroscience Commons

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Developmental Neuroscience

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Articles 91 - 120 of 179

Full-Text Articles in Molecular and Cellular Neuroscience

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell Jan 2011

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell Jan 2011

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Characterizing And Treating The Neuropathology Of Tuberous Sclerosis Complex In The Mouse, Sharon W. Way Dec 2010

Characterizing And Treating The Neuropathology Of Tuberous Sclerosis Complex In The Mouse, Sharon W. Way

Dissertations and Theses (Open Access)

Tuberous sclerosis complex (TSC) is a multisystem, autosomal dominant disorder affecting approximately 1 in 6000 births. Developmental brain abnormalities cause substantial morbidity and mortality and often lead to neurological disease including epilepsy, cognitive disabilities, and autism. TSC is caused by inactivating mutations in either TSC1 or TSC2, whose protein products are known inhibitors of mTORC1, an important kinase regulating translation and cell growth. Nonetheless, neither the pathophysiology of the neurological manifestations of TSC nor the extent of mTORC1 involvement in the development of these lesions is known. Murine models would greatly advance the study of this debilitating disorder. This thesis …


Developmental Changes In The Structure And Composition Of The Postsynaptic Density, Matthew T. Swulius May 2010

Developmental Changes In The Structure And Composition Of The Postsynaptic Density, Matthew T. Swulius

Dissertations and Theses (Open Access)

The development of the brain and its underlying circuitry is dependent on the formation of trillions of chemical synapses, which are highly specialized contacts that regulate the flow of information from one neuron to the next. It is through these synaptic connections that neurons wire together into networks capable of performing specific tasks, and activity-dependent changes in their structural and physiological state is one way that the brain is thought to adapt and store information. At the ultrastructural level, developmental and activity-dependent changes in the size and shape of dendritic spines have been well documented, and it is widely believed …


In Vitro Guidance Of Retinal Axons By A Tectal Lamina-Specific Glycoprotein Nel, Yulan Jiang, Hiroya Obama, Soh-Leh Kuan, Ritsuko Nakamura, Chizu Nakamoto, Zhufeng Ouyang, Masaru Nakamoto Jan 2009

In Vitro Guidance Of Retinal Axons By A Tectal Lamina-Specific Glycoprotein Nel, Yulan Jiang, Hiroya Obama, Soh-Leh Kuan, Ritsuko Nakamura, Chizu Nakamoto, Zhufeng Ouyang, Masaru Nakamoto

Biology Faculty Publications

Nel is a glycoprotein containing five chordin-like and six epidermal growth factor-like domains and is strongly expressed in the nervous system. In this study, we have examined expression patterns and in vitro functions of Nel in the chicken retinotectal system. We have found that in the developing tectum, expression of Nel is localized in specific laminae that retinal axons normally do not enter, including the border between the retinorecipient and non-retinorecipient laminae. Nel-binding activity is detected on retinal axons both in vivo and in vitro, suggesting that retinal axons express a receptor for Nel. In vitro, Nel inhibits retinal axon …


A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell Jan 2009

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell Jan 2009

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell Jan 2009

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Pdf Of All O'Dell Manuscripts, Laura O'Dell Jan 2009

Pdf Of All O'Dell Manuscripts, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell Jan 2009

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell Jan 2009

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell Jan 2009

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell Jan 2009

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell Jan 2009

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell Jan 2009

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell Jan 2009

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell Jan 2009

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell Jan 2009

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell Jan 2009

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell Jan 2009

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell Jan 2009

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell Jan 2009

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell Jan 2008

Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell Jan 2008

Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell Jan 2008

Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell Jan 2008

Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell Jan 2008

Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell Jan 2008

Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell Jan 2007

Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell Jan 2007

Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell

Selected Works Temporary Series

No abstract provided.