Engineering Commons^™

The Multimodal Brain Tumor Image Segmentation Benchmark (Brats), Bjoern H. Menze, Andras Jakab, Stefan Bauer, Jayashree Kalpathy-Cramer, Khan M. Iftekharuddin, Syed M.S. Reza

Electrical & Computer Engineering Faculty Publications

In this paper we report the set-up and results of the Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) organized in conjunction with the MICCAI 2012 and 2013 conferences. Twenty state-of-the-art tumor segmentation algorithms were applied to a set of 65 multi-contrast MR scans of low-and high-grade glioma patients-manually annotated by up to four raters-and to 65 comparable scans generated using tumor image simulation software. Quantitative evaluations revealed considerable disagreement between the human raters in segmenting various tumor sub-regions (Dice scores in the range 74%-85%), illustrating the difficulty of this task. We found that different algorithms worked best for different sub-regions …

Temporary Bonding With Polydimethylglutarimide Based Lift Off Resist As A Layer Transfer Platform, T. Matsumae, A. D. Koehler, J. D. Greenlee, T. J. Anderson, H. Baumgart, G. G. Jernigan, K. D. Hobart, F. J. Kub

Electrical & Computer Engineering Faculty Publications

Bonding of lift off resist (LOR) was performed to realize temporary wafer bonding without residue. Bonding process conditions such as spin speed, pre-bake temperature, and bonding temperature were optimized to obtain a large bonded area with high bond strength. Under optimized process conditions, a bonded area covering over 98% of the wafer surface, with a room temperature bond strength of nearly 5 J/m² is achieved. During razor blade testing, fracture often occurs at the Si wafer. Moreover, debonding using an N-Methyl-2-pyrrolidone (NMP)-based solvent left the wafer surface extremely small amount of residue. Thus, the optimized bonding processed developed in …

Evaluation Of The Effects Of A Plasma Activated Medium On Cancer Cells, S. Mohades, M. Laroussi, J. Sears, N. Barekzi, H. Razavi

Electrical & Computer Engineering Faculty Publications

The interaction of low temperature plasma with liquids is a relevant topic of study to the field of plasma medicine. This is because cells and tissues are normally surrounded or covered by biological fluids. Therefore, the chemistry induced by the plasma in the aqueous state becomes crucial and usually dictates the biological outcomes. This process became even more important after the discovery that plasma activated media can be useful in killing various cancer cell lines. Here, we report on the measurements of concentrations of hydrogen peroxide, a species known to have strong biological effects, produced by application of plasma to …

Spatio-Temporal Patterns Of Water Table And Vegetation Status Of A Deserted Area, Limin Duan, Tingxi Liu, Xixi Wang, Yanyun Luo

Civil & Environmental Engineering Faculty Publications

Understanding groundwater-vegetation interactions is crucial for sustaining fragile environments of desert areas such as the Horqin Sandy Land (HSL) in northern China. This study examined spatio-temporal variations in the water table and the associated vegetation status of a 9.71 km² area that contains meadowland, sandy dunes, and intermediate transitional zones. The depth of the water table and hydrometeorologic parameters were monitored and Landsat Thematic Mapper (TM) and Moderate Resolution Imaging Spectroradiometer (MODIS) data were utilized to assess the vegetation cover. Spatio-temporal variations over the six-year study period were examined and descriptive groundwater-vegetation associations developed by overlaying a water table …

Reminiscing About 15 Years Of Interoperability Efforts, Herbert Van De Sompel, Michael L. Nelson

Computer Science Faculty Publications

Over the past fifteen years, our perspective on tackling information interoperability problems for web-based scholarship has evolved significantly. In this opinion piece, we look back at three efforts that we have been involved in that aptly illustrate this evolution: OAI-PMH, OAI-ORE, and Memento. Understanding that no interoperability specification is neutral, we attempt to characterize the perspectives and technical toolkits that provided the basis for these endeavors. With that regard, we consider repository-centric and web-centric interoperability perspectives, and the use of a Linked Data or a REST/HATEAOS technology stack, respectively. We also lament the lack of interoperability across nodes that play …

A Framework And System For A Multi-Model Decision Aid For Sustainable Farming Practices, Kasi Bharath Vegesana

Computational Modeling & Simulation Engineering Theses & Dissertations

Decision support systems (DSS) for farmers address the need for modeling multiple processes and scenarios that affect farmer decision making. Existing DSS have various drawbacks that stop them from being deployed as decision support tools. This research proposes a multi-model simulation framework that can be used to analyze farm management practices at the crop level, individual farm level and at the community level to show the impact and alternatives for smallholder farming practices. A generic crop growth model is proposed, based on existing equations. We run sensitivity analysis on the model to identify important variables. The outputs from the crop …

Multi-Surface Simplex Spine Segmentation For Spine Surgery Simulation And Planning, Rabia Haq

Computational Modeling & Simulation Engineering Theses & Dissertations

This research proposes to develop a knowledge-based multi-surface simplex deformable model for segmentation of healthy as well as pathological lumbar spine data. It aims to provide a more accurate and robust segmentation scheme for identification of intervertebral disc pathologies to assist with spine surgery planning. A robust technique that combines multi-surface and shape statistics-aware variants of the deformable simplex model is presented. Statistical shape variation within the dataset has been captured by application of principal component analysis and incorporated during the segmentation process to refine results. In the case where shape statistics hinder detection of the pathological region, user-assistance is …

Safety Culture Monitoring: A Management Approach For Assessing Nuclear Safety Culture Health Performance Utilizing Multiple-Criteria Decision Analysis, James Harold Warren Jr.

Engineering Management & Systems Engineering Theses & Dissertations

Nuclear power plants are among the most technologically complex of all energy facilities. This complexity reflects the precision needed in design, maintenance and operations to harness the energy of the atom safely, reliably and economically. Nuclear energy thus requires consistent, high levels of organizational performance by the highly skilled professionals who operate and maintain nuclear power plants (Nuclear Energy Institute [NEI], 2014, p. 1).

A key element for achieving consistent, high levels of performance in a nuclear organization is its safety culture. Nuclear safety culture is for an organization what character and personality is for an individual: a feature that …

Strategies For Sensor Data Aggregation In Support Of Emergency Response, X. Wang, A. Walden, M. Weigle, S. Olariu

Computer Science Presentations

PDF of a powerpoint presentation from the Military Communications Conference (MILCOM), Baltimore, Maryland, October 7, 2014. Also available on Slideshare.

Data Completion Methods For Improved Developmental Stage Annotation Of Drosophila Embryos In Images, Chitsanu Janyalikit

Electrical & Computer Engineering Theses & Dissertations

Drosophila melanogaster is a dominant model organism for studying the function of animal genes in initial stages of embryogenesis. Usually, images containing Drosophila gene expression patterns are captured at different developmental stages to study the interconnection of animal genes. To achieve most biologically meaningful results, gene expression images from a similar stage should be compared. Currently, biologists manually classify embryos in images into different stages, which is time intensive and infeasible for current massively produced gene expression images. Therefore, there is a need to develop an automatic system for the annotation.

Gene expression information in embryo images usually appears as …

Numerical Studies Of The A6 Relativistic Magnetron Using Particle-In-Cell Simulations, Vineetha Jujjavarapu

Electrical & Computer Engineering Theses & Dissertations

The magnetron became a major component in radar systems around the time of the World War II. More recent radar techniques require short microwave pulses (with nanosecond pulse-widths for ultra wideband operations) and high peak power in the Giga-Watt range. In order to achieve these specifications for the military, the magnetron needs to have both a fast start and the rapid growth rate of oscillations in order to serve as a microwave source for the short-pulse applications. These two factors depend on the geometry of the cathode. Other requirements include high conversion efficiency and low leakage current (in order to …

Simulation Studies Of Organic Solar Cell Structure And Morphology On The Device Efficiency, Satish Kumar Reddy Kota

Electrical & Computer Engineering Theses & Dissertations

Solar cells based on organic materials offer several advantages over the traditional solar cells made with inorganic materials. These include a lower impact on nature, smaller weight, the avoidance of cleanrooms for their production, their flexibility which makes it possible to wrap or coat them on objects with varying shapes and geometries, and most significantly their ability to produce electricity in diffuse'd light which is a distinct advantage over conventional solar cells. Organic solar cells have their own disadvantage of very low efficiencies as compared to inorganic solar cells. The morphology and structure of the organic solar cells plays a …

Discretized Agent-Based Model Of Infectious Disease Spread That Uses Contact Probability, Tyrell L. Gardner

Computational Modeling & Simulation Engineering Theses & Dissertations

This study uses contact probability in an agent-based model to simulate the spread of an infectious disease. In order to perform the study, the agent-based model must first be discretized into events. Each agent in the model is given its own infectious disease state machine taken from the Susceptible-Exposed-Infected-Recovered (SEIR) model. The agents move between squares in a grid environment where each square represents a group. Groups have a contact probability as an attribute that is used to predict whether an agent comes in close contact with another agent. The transitions between the states in the SEIR model are easily …

Effective Cfrp Retrofitting Schemes For Prestressed Concrete Beams, Herish Abdullah Hussein

Civil & Environmental Engineering Theses & Dissertations

This thesis presents a detailed theoretical study of a number of retrofitting schemes for prestressed concrete beams using carbon fiber reinforced polymer (CFRP) sheets to increase flexural strength and ductility. A simply-supported beam subjected to a gradually increasing uniformly distributed load is adopted for the study with a variety of CFRP retrofiring schemes. Three different types of beam cross sections are included for quantifying the influence of CFRP retrofitting when used in high compression regions in addition to CFRP use in high tension areas. To achieve this goal, nonlinear moment curvature relations are developed and coupled with a finite-difference solution …

Engineering Design: A Cognitive Process Approach, Greg Joseph Strimel

STEMPS Theses & Dissertations

The intent of this dissertation was to identify the cognitive processes used by advanced pre-engineering students to solve complex engineering design problems. Students in technology and engineering education classrooms are often taught to use an ideal engineering design process that has been generated mostly by educators and curriculum developers. However, the review of literature showed that it is unclear as to how advanced pre-engineering students cognitively navigate solving a complex and multifaceted problem from beginning to end. Additionally, it was unclear how a student thinks and acts throughout their design process and how this affects the viability of their solution. …

Laminar Deflagrated Flame Interaction With A Fluidic Jet Flow For Deflagration-To-Detonation Flame Acceleration, Joseph P. Mcgarry

Mechanical & Aerospace Engineering Theses & Dissertations

The concept of the Pulse Detonation Engine (PDE) has been of interest for centuries. The issue was originally studied to understand flame propagation in mine shafts after explosions due to methane buildup. The flames would travel down the shafts, transitioning to turbulent flames due to the roughness of the shaft walls, and accelerate to detonation, delivering powerful, destructive forces. The potential for efficient energy production was noticed, and the theory behind flame propagation was later applied to developing propulsion systems. Recently, researchers have begun to understand the full potential of PDEs to efficiently produce an immense amount of thrust due …

Design Improvements For A Reusable Horizontal Takeoff And Landing Aircraft For Use On Mars, Brian A. Skoog

Mechanical & Aerospace Engineering Theses & Dissertations

Unmanned aerial vehicle capabilities are required for expanded exploration of the Martian surface. These vehicles can not only gather data at an altitude otherwise unreachable by rovers and satellites, but also deliver small payloads and retrieve samples from distant off-site locations. Previous multi-purpose reusable Mars aircraft studies have been unable to achieve the flight ranges required for expanded exploration. This study has focused on increasing the range of prototype aircraft designs. Assuming that large precision cargo delivery capabilities have been developed and much of the infrastructure associated with a fixed Mars base is in place, the challenge of linking dispersed …

Emergency Diesel-Electric Generator Set Maintenance And Test Periodicity, Stephen John Fehr

Engineering Management & Systems Engineering Theses & Dissertations

Manufacturer and industry recommendations vary considerably for maintenance and tests of emergency diesel-electric generator sets supporting critical operations power systems facilities. There is little consistency among sets of similar technology, and manufacturers and their representatives often provide contradictory guidance. As a result, periodicity of emergency diesel-electric generator set maintenance and tests varies considerably in practice. This work proposes and tests a research and analysis framework to develop parametric regression survival models of modern diesel-electric generator sets in emergency standby duty as a function of maintenance periodicity, test periodicity, and other predictors. Within this framework, predictors are developed from common maintenance …

Methods For Initial Relative Orbit Determination Using Angles-Only Observations, Ethan M. Pratt

Mechanical & Aerospace Engineering Theses & Dissertations

An approximate second order nonlinear closed-form solution for three-dimensional relative motion assuming Keplerian dynamics and a circular reference track are applied to the relative initial orbit determination problem. A series of azimuth-elevation angular measurements locating a deputy satellite with respect to a chief satellite are coupled through the observation geometry with the nonlinear dynamics model for the relative motion in terms of linear, quadratic, and bilinear combinations of the deputy initial conditions and chief orbital elements. The resulting set of nonlinear measurement equations are analyzed, formulated, and solved using three separate non-iterative methods. By using a nonlinear dynamics model with …

Camera Viewpoint Invariant Vehicular Traffic Segmentation And Classification, Jeffrey B. Flora

Electrical & Computer Engineering Theses & Dissertations

The goal of this intelligent transportation systems work is to develop a computer vision method that is view angle independent for segmenting and classifying vehicular traffic on highway systems. In order to achieve this goal, this work implements an algorithm for vehicle segmentation, feature extraction, and classification using the existing Virginia Department of Transportation (VDOT) infrastructure on networked traffic cameras. The VDOT traffic video is analyzed for vehicle detection and segmentation using an adaptive Gaussian mixture model algorithm. Speed estimation is performed using a single camera calibration. Size and shape features from morphological properties and texture features from histogram of …

Study Of Polyaniline For Use In An Organic Field Effect Transistor, Thomas Martin Sprinkle

Chemistry & Biochemistry Theses & Dissertations

Polyaniline's emeraldine base form was synthesized via chemical polymerization in HCl acidic media utilizing ammonium persulfate as the oxidant. Synthesis was done at room temperature and -30 'C and characterized for differences by X-ray diffraction, thermogravimetric analysis, and differential scanning calorimetry. Methanol soxhlet extraction was done to increase number average molecular weight from 77,400 to 81,000 and decrease the poly dispersity index from 3.82 to 2.14. Films were cast using N, N'- Dimethylpropyleneurea and N-Methylpyrrolidone and showed poor mechanical properties upon acidic doping.

Cyclic voltammetry was done with HC1 as the acidic media and an ITO coated slide as the …

Hydro-Climate Temporal Variations And Their Influences On Net Primary Production In A Eurasian Steppe Watershed, Xiaomin Yang

Civil & Environmental Engineering Theses & Dissertations

Climate, which is the most important factor that influences Net Primary Productivity, has been detected changing all over the world. The confounding effects of step change invalidate the stationarity assumption of commonly used trend analysis methods such as the Mann-Kendall test technique, so previous studies have failed to explain inconsistencies between detected trends and observed large anomalies. In this research, by formulating a trend analysis approach that considers nonstationary due to step changes, trends and extreme occurrences of precipitation, temperature, and runoff in annual, seasonal, and monthly scales were analyzed in a mid-latitude Eurasian steppe watershed in northeast China, and …

Anammox Polishing In Mainstream Wastewater Treatment To Meet Stringent Ammonia And Total Nitrogen Limits, Rebecca Mary Holgate

Civil & Environmental Engineering Theses & Dissertations

As nitrogen discharge limits are becoming more stringent there is a need for new processes that are sustainable and cost effective. Since anaerobic ammonia oxidizing bacteria (anammox) were discovered in the mid 1990s, there has been considerable success implementing anammox in many wastewater treatment plants to treat internally generated nitrogen rich waste streams (e.g. centrate). Recently, there has also been discussion of implementing anammox in mainstream wastewater treatment to exploit the benefits of autotrophic nitrogen removal.

A two stage A/B pilot study was conducted that included a high-rate activated sludge (HRAS) process followed by a two-stage de-ammonification process incorporating nitrite-shunt …

Meshless Mechanics And Point-Based Visualization Methods For Surgical Simulations, Rifat Aras

Computational Modeling & Simulation Engineering Theses & Dissertations

Computer-based modeling and simulation practices have become an integral part of the medical education field. For surgical simulation applications, realistic constitutive modeling of soft tissue is considered to be one of the most challenging aspects of the problem, because biomechanical soft-tissue models need to reflect the correct elastic response, have to be efficient in order to run at interactive simulation rates, and be able to support operations such as cuts and sutures.

Mesh-based solutions, where the connections between the individual degrees of freedom (DoF) are defined explicitly, have been the traditional choice to approach these problems. However, when the problem …

Numerical Study Of Poration And Ionic Conduction In Nanopores Caused By High-Intensity, Nanosecond Pulses In Cell, Hao Qiu

Electrical & Computer Engineering Theses & Dissertations

This dissertation focuses on the dynamics and bioeffects of electroporation of biological cell and ionic conduction in nanopores under high-intensity, nanosecond pulses. The electroporation model utilized the current continuity equation and the asymptotic Smoluchowski equation to explore the transmembrane potential and pore density of the plasma and intracellular membranes; the ionic conduction model employed the Poisson-Nernst-Planck equations and the Navier-Stokes equations to analyze the ionic current and ion concentration profile.

Nanosecond electric pulses of high-intensity amplitude can initiate electroporation of intracellular organelles. The pulse parameters and cell electrical properties, that can selectively electroporate liposomes but keep the plasma and nuclear …

Investigation And Optimization Of A New Compact Superconducting Cavity For Deflecting And Crabbing Applications, Subashini Uddika De Silva

Physics Theses & Dissertations

Deflecting and crabbing structures have many applications in current accelerator systems. The primary use of a deflecting cavity is to separate a single beam into multiple beams. A crabbing cavity enables the head-on collision at the interaction point in particle colliders in order to increase the luminosity. The early uses of the deflecting structures have been in the early 1960s: these structures were disk loaded structures operating at room temperature. The crabbing structure which was installed at the NEK electron-positron collider was the first and only operational superconducting cavity of that kind. The most common design of superconducting deflecting and …

Time-Based Collision Risk Modeling For Air Traffic Management, Alan E. Bell

Engineering Management & Systems Engineering Theses & Dissertations

Since the emergence of commercial aviation in the early part of last century, economic forces have driven a steadily increasing demand for air transportation. Increasing density of aircraft operating in a finite volume of airspace is accompanied by a corresponding increase in the risk of collision, and in response to a growing number of incidents and accidents involving collisions between aircraft, governments worldwide have developed air traffic control systems and procedures to mitigate this risk. The objective of any collision risk management system is to project conflicts and provide operators with sufficient opportunity to recognize potential collisions and take necessary …

A Method To Define Requirements For System Of Systems, Randy Gene Walker

Engineering Management & Systems Engineering Theses & Dissertations

The purpose of this research was to develop and apply a systems-based method for defining System of Systems (SoS) requirements using an inductive research design. Just as traditional Systems Engineering (TSE) includes a requirements definition phase, so too does System of Systems Engineering (SoSE); only with a wider, more over- arching, systemic perspective. TSE addresses the design and development of a single system with generally a very specific functional purpose enabled by any number of subcomponents. SoSE however, addresses the design and development of a large, complex system to meet a wide range of functional purposes enabled by any number …

The Study Of Electrostatic And Magnetostatic Active Space Radiation Shielding For Deep Space Missions, Leroy A. Fung

Electrical & Computer Engineering Theses & Dissertations

A goal of the National Aeronautics and Space Administration (NASA) has been to develop technologies that will enable deep space explorations. Such missions include a prolonged stay on the Moon and the ability to sustain a long duration of travel time to Mars and beyond. Long-term human exposures to radiation are a crucial concern. Recent research has taken focus on active and passive shielding methods as a way of eliminating the hazard posed by radiation particles. Passive shielding involves the use of materials that has the ability to withstand radiation particles and reduce the dose by stopping or slowing the …

Evaluation Of The Epa Swmm Model To Simulate Low Impact Development Features In An Urban Stormwater Environment, Holly Ann Carpenter

Civil & Environmental Engineering Theses & Dissertations

This research thesis explores the use of the Environmental Protection Agency's (EPA) Stormwater Water Management Model (SWMM) to model an urban watershed with a developed stormwater management system and test the SWMM model's ability to simulate Low Impact Development (LID) features by proposing typical LID features that can be retrofitted to the developed study area. The SWMM model is established with an existing survey of the study area's stormwater management system, and due to the lack of field data for the study area, the model developed in this research thesis is calibrated with the consideration of a published stormwater model …