Hierarchical Based Classifcation Method Based On Fusion Ofgaussian Map Descriptors Foralzheimer Diagnosis Using T1‑Weighted Magnetic Resonance Imaging,
2023
The British University in Egypt
Hierarchical Based Classifcation Method Based On Fusion Ofgaussian Map Descriptors Foralzheimer Diagnosis Using T1‑Weighted Magnetic Resonance Imaging, Nourhan Zayed, Shereen E. Morsy, Inas A. Yassine
Mechanical Engineering
Alzheimer’s disease (AD) is considered one of the most spouting elderly diseases. In 2015, AD is reported the US’s sixth cause of death. Substantially, non-invasive imaging is widely employed to provide biomarkers supporting AD screening, diagnosis, and progression. In this study, Gaussian descriptors-based features are proposed to be efcient new biomarkers using Magnetic Resonance Imaging (MRI) T1-weighted images to diferentiate between Alzheimer’s disease (AD), Mild Cognitive Impairment (MCI), and Normal controls (NC). Several Gaussian map-based features are extracted such as Gaussian shape operator, Gaussian curvature, and mean curvature. The aforementioned features are then introduced to the Support Vector Machine (SVM). …
Hemodynamic Assessment Of Y-Incision Aortic Root Enlargement Using Computational Simulations,
2023
University of Denver
Hemodynamic Assessment Of Y-Incision Aortic Root Enlargement Using Computational Simulations, Astitwa Ghimire
Electronic Theses and Dissertations
The Yang procedure is a new aortic root enlargement technique used to enlarge the aortic annulus by multiple valve sizes. The procedure prevents patient prosthesis mismatch and establishes a viable platform for future valve-in-valve implantation. This study used the Yang procedure to investigate the hemodynamics in the aortic root and bioprosthetic valve regions after aortic root enlargement. Results indicate the velocity magnitude at the sinus regions of a patient who underwent the Yang procedure was slower, indicating risks of flow stasis and thrombosis. Simulation results denote computational models can be created for optimization of surgical procedures.
Development Of A Soft Robotic Approach For An Intra-Abdominal Wireless Laparoscopic Camera,
2023
University of Tennessee, Knoxville
Development Of A Soft Robotic Approach For An Intra-Abdominal Wireless Laparoscopic Camera, Hui Liu
Doctoral Dissertations
In Single-Incision Laparoscopic Surgery (SILS), the Magnetic Anchoring and Guidance System (MAGS) arises as a promising technique to provide larger workspaces and field of vision for the laparoscopes, relief space for other instruments, and require fewer incisions. Inspired by MAGS, many concept designs related to fully insertable magnetically driven laparoscopes are developed and tested on the transabdominal operation. However, ignoring the tissue interaction and insertion procedure, most of the designs adopt rigid structures, which not only damage the patients' tissue with excess stress concentration and sliding motion but also require complicated operation for the insertion. Meanwhile, lacking state tracking of …
A Virtual Method For Establishing Femoral Stem Position In Total Hip Arthroplasty,
2023
University of Denver
A Virtual Method For Establishing Femoral Stem Position In Total Hip Arthroplasty, Samuel Mattei
Electronic Theses and Dissertations
Total hip arthroplasty (THA) is one of the most successful orthopedic surgeries performed, in which the hip joint is reconstructed to improve functionality and decrease pain in the joint. Despite the success of these procedures, femoral stem misalignment remains an area that influences THA success. The relationship between the femoral stem geometry and implanted femoral stem size and orientation is underreported due to limitations in the collection of radiographic data used for clinical pre-operative templating. Furthermore, the influence of anatomic measurements on the direction and size of the femoral stem are not considered due to imaging technique and difficulties associated …
Finite Element Modeling Of Patient-Specific Total Shoulder Arthroplasty,
2023
University of Denver
Finite Element Modeling Of Patient-Specific Total Shoulder Arthroplasty, Ignacio Rivero Crespo
Electronic Theses and Dissertations
Total Shoulder Arthroplasty (TSA) is a surgical procedure designed to improve joint functionality by replacing the articulation between the humeral head and the glenoid fossa. Anatomic Total Shoulder Arthroplasty (aTSA) and Reverse Total Shoulder Arthroplasty (rTSA) are two types of replacement surgery to relieve pain and restore function of the shoulder. The overall goal of this study was to evaluate the effects of variation of certain patient and implant alignment parameters that may influence long-term outcomes of these surgical procedures, including kinematics, joint loads and contact mechanics. Computational models of six TSA subjects, three aTSA and three rTSA, were created …
Biomat (Biomechanics Multiactivity Transformer) Model,
2023
University of Denver
Biomat (Biomechanics Multiactivity Transformer) Model, Mohsen Sharifi Renani
BioMAT (Biomechanics Multiactivity Transformer)
No abstract provided.
Mechanical Response Of The Craniofacial Skeleton To Subfracture Impacts In The Time And Frequency Domains,
2023
Western University
Mechanical Response Of The Craniofacial Skeleton To Subfracture Impacts In The Time And Frequency Domains, Paige Merko
Electronic Thesis and Dissertation Repository
Resonant frequencies have been suggested as a mechanism of brain injury since these vibrations can transfer energy into the brain. Study of the vibrational response of the craniofacial skeleton to impact is limited in literature. In this research, four cadaver specimens were impacted at five locations on the craniofacial skeleton. The mechanical response to each impact was compared in the time and frequency domains. Impacts to the maxilla and its associated soft tissues tended to be attenuated, while impacts to the cranial vault, specifically to the occipital, produced the most severe response. Results suggest that the facial skeleton and its …
Biomechanical Knee Joint For Exoskeleton,
2023
California Polytechnic State University, San Luis Obispo
Biomechanical Knee Joint For Exoskeleton, Gabriel Ireton Ahern, Calloway Miller, Christianna Altamura, Eric Mailes
Mechanical Engineering
Our senior design project consisted of designing and manufacturing a biomechanically accurate, actuated knee joint to be integrated into an exoskeleton being developed by the Lower Limb Exoskeleton Assist Project (LLEAP), a part of the EMPOWER student association at Cal Poly, San Luis Obispo. As the human knee flexes and extends throughout gait motion, the center of rotation changes. Currently marketed exoskeletons have one point of rotation, which over constrains the knee and causes misalignment between the user and the suit [1]. Our goal was to mimic natural knee joint motion by changing the center or rotation, thus reducing misalignment …
Bespoke Bicycle Enclosure,
2023
California Polytechnic State University, San Luis Obispo
Bespoke Bicycle Enclosure, Thomas Link, Kyle Mcafee, Marc Monier, Hunter Walden
Mechanical Engineering
Brian Higgins is an American veteran with retinitis pigmentosa who relies on cycling for transportation. The motivation for this project is to design and manufacture a refined prototype bicycle attachment to support him while biking in the rain and cold. The attachment will serve to enclose him for optimal protection from inclement weather, while maintaining sufficient mobility for daily cycling. Mr. Higgins’ bicycle is equipped with an attached sensor system which assists his visual impairment by using an ultrasonic sensor. Therefore, the attachment cannot adversely affect the function of the sensor system. The project timeline is set at approximately 7 …
Fully Coupled Fluid Structure Interaction Simulation Of Bioprosthetic Heart Valves: A Numerical And Experimental Analysis,
2023
University of Denver
Fully Coupled Fluid Structure Interaction Simulation Of Bioprosthetic Heart Valves: A Numerical And Experimental Analysis, Masod Sadipour
Electronic Theses and Dissertations
Aortic stenosis impacts approximately 7% of the global population. In the past decade, the role of computational modeling has been becoming considerably important in the design of BHVs. To obtain reliable solutions in computational modeling, it is essential to consider accurate properties of bioprosthetic heart valves (BHVs), such as density and mechanical properties. Previous computational studies assumed (bovine pericardium) BP used in BHVs density was comparable to water or blood. Yet, BP is subjected to multiple treatments like fixation and anti-calcification. In Chapter 2, I measured BP density and its effect on BHV leaflet stress and strain. In the second …
Patient Movement Monitoring Based On Imu And Deep Learning,
2023
University of Denver
Patient Movement Monitoring Based On Imu And Deep Learning, Mohsen Sharifi Renani
Electronic Theses and Dissertations
Osteoarthritis (OA) is the leading cause of disability among the aging population in the United States and is frequently treated by replacing deteriorated joints with metal and plastic components. Developing better quantitative measures of movement quality to track patients longitudinally in their own homes would enable personalized treatment plans and hasten the advancement of promising new interventions. Wearable sensors and machine learning used to quantify patient movement could revolutionize the diagnosis and treatment of movement disorders. The purpose of this dissertation was to overcome technical challenges associated with the use of wearable sensors, specifically Inertial Measurement Units (IMUs), as a …
Novel Approach For Non-Invasive Prediction Of Body Shape And Habitus,
2023
University of Denver
Novel Approach For Non-Invasive Prediction Of Body Shape And Habitus, Emma Young
Electronic Theses and Dissertations
While marker-based motion capture remains the gold standard in measuring human movement, accuracy is influenced by soft-tissue artifacts, particularly for subjects with high body mass index (BMI) where markers are not placed close to the underlying bone. Obesity influences joint loads and motion patterns, and BMI may not be sufficient to capture the distribution of a subject’s weight or to differentiate differences between subjects. Subjects in need of a joint replacement are more likely to have mobility issues or pain, which prevents exercise. Obesity also increases the likelihood of needing a total joint replacement. Accurate movement data for subjects with …
Flexible Magnetic Skin Sensor Array For Torsion Perception,
2023
Florida Atlantic University
Flexible Magnetic Skin Sensor Array For Torsion Perception, Lucja Stawikowska, Erik D. Engeberg
36th Florida Conference on Recent Advances in Robotics
Prosthetic hands help upper limb amputees and people who were born without hands. Currently, these prostheses are rather rudimentary and do not provide adequate sensing capabilities compared to a human hand. People use their natural hands to perceive complex tactile phenomena such as shear and torsion using thousands of mechanoreceptors in their fingertips. The capability to detect torsional loads at the fingertips is a notable gap in prosthetic hand sensation. Flexible tactile sensors are a promising new technology that would be ideal for prosthetic hands since they allow for stretching and movement like human skin without damage to the sensor. …
Du Undergraduate Showcase: Research, Scholarship, And Creative Works,
2023
University of Denver
Du Undergraduate Showcase: Research, Scholarship, And Creative Works, Caitlyn Aldersea, Justin Bravo, Sam Allen, Anna Block, Connor Block, Emma Buechler, Maria De Los Angeles Bustillos, Arianna Carlson, William Christensen, Olivia Kachulis, Noah Craver, Kate Dillon, Muskan Fatima, Angel Fernandes, Emma Finch, Colleen Cassidy, Amy Fishman, Andrea Francis, Stacia Fritz, Simran Gill, Emma Gries, Rylie Hansen, Shannon Powers, Jacqueline Martinez, Zachary Harker, Ashley Hasty, Mykaela Tanino-Springsteen, Kathleen Hopps, Adelaide Kerenick, Colin Kleckner, Ci Koehring, Elijah Kruger, Braden Krumholz, Maddie Leake, Lyneé Alves, Seraphina Loukas, Yatzari Lozano Vazquez, Haley Maki, Emily Martinez, Sierra Mckinney, Mykaela Tanino-Springsteen, Audrey Mitchell, Kipling Newman, Audrey Ng, Megan Lucyshyn, Andrew Nguyen, Stevie Ostman, Casandra Pearson, Alexandra Penney, Julia Gielczynski, Tyler Ball, Anna Rini, Christina Rorres, Simon Ruland, Helayna Schafer, Emma Sellers, Sarah Schuller, Claire Shaver, Kevin Summers, Isabella Shaw, Madison Sinar, Claudia Pena, Apshara Siwakoti, Carter Sorensen, Madi Sousa, Anna Sparling, Alexandra Revier, Brandon Thierry, Dylan Tyree, Maggie Williams, Lauren Wols
DU Undergraduate Research Journal Archive
DU Undergraduate Showcase: Research, Scholarship, and Creative Works
Investigating The Effectiveness Of A Haptic Feedback System To Improve The Gait Speed Of Older Adults In Overground Walking,
2023
The University of Maine
Investigating The Effectiveness Of A Haptic Feedback System To Improve The Gait Speed Of Older Adults In Overground Walking, Md Tanzid Hossain
Electronic Theses and Dissertations
While the use of tactile feedback for modifying gait has recently shown promising results in a number of research studies, there has been little attention given to its ability to effect change in the gait of older adults nor has the effect of the frequency of this feedback been examined. Given the important associations of walking speed with the health of older adults, the goal of this study was to determine if a recently developed haptic feedback system could increase the walking speed of older adults and whether the frequency at which this feedback was provided would have an impact …
Steam Gasification Of Biochar To Produce Hydrogen-Rich Syngas,
2023
Georgia Southern University
Steam Gasification Of Biochar To Produce Hydrogen-Rich Syngas, Nnamdi Ofuani
Honors College Theses
A key greenhouse gas (GHG) emission contributing to climate change is carbon dioxide (CO2) emission. This emission is largely due to the use of fossil fuel as a major energy source. Biomass is an alternative energy source. Biochar, a byproduct of the pyrolysis process (of biomass), could be gasified to produce syngas (a mixture of CO and H2). This syngas can further be used to produce different kinds of fuels like biodiesel, bio-gasoline, bioethanol, etc. In the steam gasification of biochar, the quality and yield of syngas is dependent on parameters such as temperature, particle size, …
Structure And Movement Design To Build A Functional Prosthetic Hand,
2023
Murray State University
Structure And Movement Design To Build A Functional Prosthetic Hand, John Campbell
Honors College Theses
This project aims to create a functional prosthetic hand that will improve upon the previous design for this project. The previous design included four fingers which were moved using a four-bar linkage and slider crank mechanism in combination with a linear actuator to move all four fingers in unison. Two servo motors were used to create an opposable thumb that could be used to grasp objects. Movement of the prosthetic hand was activated using a signal received from a myoelectric sensor. The goal of this project is to study this design and attempt to upgrade the prosthetic hand utilizing a …
Blood Flow Regulates Atherosclerosis Progression And Regression,
2023
University of Nebraska–Lincoln
Blood Flow Regulates Atherosclerosis Progression And Regression, Morgan A. Schake
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Atherosclerosis is the most prevalent pathology of cardiovascular disease with no known cure. Despite the many systemic risk factors for atherosclerosis, plaques do not form randomly in the vasculature. Instead, they form around bifurcations and the inner curvature of highly curving arterial segments that contain so-called disturbed blood flow that is low in magnitude and multidirectional over the cardiac cycle. Conversely, straight, non-bifurcated arterial segments that contain moderate-to-high and unidirectional (i.e., normal) blood flow are protected from plaque development. Thus, blood flow is a key regulator of atherosclerosis that may be able to be leveraged to develop new therapeutics. Towards …
Surface Engineering And Microfabrication Of Pdms-Based Devices For Women’S Health Applications,
2023
University of Massachusetts Amherst
Surface Engineering And Microfabrication Of Pdms-Based Devices For Women’S Health Applications, Jamar Hawkins
Doctoral Dissertations
Poly(dimethylsiloxane) (PDMS) is a widely used polymer in biomedical and microfluidics research due to its optical transparency, castability, gas permeability, and relative biocompatibility. However, while the favorable intrinsic properties of the polymer are typically suitable for preventing experimental artifacts, the true advantage of these devices often comes from their customized patterning and design, which can be tailored to specific applications. Critical parameters in biomedical applications such as chemical concentration profiles, fluid streamlines, substrate topography, and mechanical stiffness can all be fine-tuned simply by selecting the appropriate dimensions and arrangement of PDMS microstructures. To address challenges in expanding the application of …
Hybrid Fes-Exoskeleton Control: Using Mpc To Distribute Actuation For Elbow And Wrist Movements,
2023
Rice University
Hybrid Fes-Exoskeleton Control: Using Mpc To Distribute Actuation For Elbow And Wrist Movements, Nathan Dunkelberger, Jeffrey Berning, Eric M. Schearer, Marcia K. O'Malley
Mechanical Engineering Faculty Publications
Introduction: Individuals who have suffered a cervical spinal cord injury prioritize the recovery of upper limb function for completing activities of daily living. Hybrid FES-exoskeleton systems have the potential to assist this population by providing a portable, powered, and wearable device; however, realization of this combination of technologies has been challenging. In particular, it has been difficult to show generalizability across motions, and to define optimal distribution of actuation, given the complex nature of the combined dynamic system. Methods: In this paper, we present a hybrid controller using a model predictive control (MPC) formulation that combines the actuation of both …
