Human and Clinical Nutrition Commons^™

Long-Term Supplementation With Leucine Does Not Prevent Development Of Obesity In Rats Fed A High-Fat Diet, Dameon Smith

Graduate Theses and Dissertations

Excess dietary fat consumption has been implicated in the development of obesity and diabetes. Obesity can be characterized by a disproportionate increase in fat mass compared to lean body mass. However, if muscle mass can be increased or maintained in obesity, this may facilitate weight loss by increasing the body’s overall metabolic capacity. Historically, supplementation with the branched-chain amino acid leucine has been shown to increase muscle protein synthesis via the protein kinase mTORC1. Recent studies suggest that supplementation with leucine also has the potential to reduce weight gain and fat deposition in high-fat fed, obese mice. The objective of …

The Impact Of Fast Food Marketing On Millennials, Kabo Tuelo Segokgo

Graduate Theses and Dissertations

Fast food marketing is an effective tool used by businesses to build food brand recognition among their consumers. Increased fast food consumption has been linked to the increase in high calorie consumption. This study sought among Millennials to assess the association between fast food marketing and consumption of fast food. It further dealt with perceptions on the relationship between fast food consumption and weight gain. A convenience sample of 507 participants was used to collect data from University of Arkansas’ students through an online survey and an in person survey. An independent sample t test and multivariate analysis of variance …

3-Hydroxy Fatty Acid Induce Trophoblast And Hepatocyte Lipoapoptosis, Taylor Bruett, Taylor Heng, Sathish Kumar Natarajan

UCARE Research Products

Acute Fatty Liver of Pregnancy (AFLP) is a very rare and fatal condition for both the mother and the unborn offspring accompanied by severe maternal liver dysfunction. AFLP usually develops during the third trimester of pregnancy with symptoms of liver disease. AFLP is associated with a mutation in the enzyme, long-chain 3-hydroxy acyl CoA dehydrogenase (LCHAD) which is involved in the mitochondrial beta-oxidation of fatty acids. Defective beta-oxidation of fatty acids results in the individual unable to metabolize fatty acids which then causes fatty infiltration in their organs, such as the liver. This interferes with normal function of the liver …

Vitamin K2 (Menaquinone) Supplementation And Its Benefits In Cardiovascular Disease, Osteoporosis, And Cancer, Grant S. Buchanan, Md, Thomas Melvin, Brandon Merritt, Charles Bishop, Md, Franklin D. Shuler, Md, Phd

Marshall Journal of Medicine

Vitamin K is known to play an essential role in the coagulation cascade; however, a growing body of research has found that a subtype of this vitamin, vitamin K₂ (menaquinone) may have a beneficial effect in osteoporosis, cardiovascular disease, and cancer. This purpose of this article is to provide a comprehensive review of recent literature regarding menaquinone and its role in human health. This review discusses the physiology of menaquinone, its clinical benefits in cardiovascular disease, osteoporosis, and cancer, and how it may interact with certain medications. The authors conclude that menaquinone supplementation has been shown to improve carboxylation …

Breastfeeding: The Illusion Of Choice, Yeon Bai, Lauren Dinour

Department of Nutrition and Food Studies Scholarship and Creative Works

Background

Breastfeeding is frequently described as a woman's decision, yet this choice is often illusionary owing to suboptimal social and structural supports. Despite the passage of the Patient Protection and Affordable Care Act (2010) that requires all qualifying employers to provide mothers “reasonable” break time and a private, non-bathroom space to express breast milk, the majority of women in the United States still do not have access to both accommodations.

The Problem

At least three issues may be influencing this suboptimal implementation at workplaces: 1) federal law does not address lactation space functionality and accessibility, 2) federal law only …

Evaluating The Role Of Intestinal Transporters In Fruit Juice-Drug Interactions, Mandy Mj Li

Electronic Thesis and Dissertation Repository

Fruit juice-drug interactions (FJDIs) involving non-metabolized oral medications result in decreased drug exposure that may lead to reduced therapeutic efficacy. The effect is thought to be mediated by inhibition of the intestinal drug transporters organic anion transporting polypeptide 1A2 and 2B1 (OATP1A2 and OATP2B1) by fruit juice constituents, however the exact mechanisms remain controversial. We tested the hypothesis that fruit juices limit the absorption of fexofenadine through interactions with specific intestinal transporters. In vitro transport and fruit juice inhibition studies using fexofenadine, a medication involved in FJDIs, revealed that in addition to previously implicated transporters, organic cation transporter 1 (OCT1) …

Jumpin’ Jacks: Social Marketing Campaign Aimed To Increase Awareness Of Healthful Behavior In South Dakota Fourth Grade Students, Megan N. Olesen, Kendra Kattelmann, Jessica Meendering, Suzanne Stluka

Health and Nutritional Sciences Faculty Publications

This study investigated the influence of utilizing a collegiate mascot as a marketing tool for the promotion of fruit and vegetable intake and physical activity among 4th grade students. The program utilized service learning and formative research for the development of a social marketing campaign comprised of nutrition education and brand marketing. A pre-test/post-test design was used to measure fruit and vegetable intake and physical activity in participants in intervention and control schools. Awareness and understanding of the campaign was assessed post-intervention. There were no changes in fruit and vegetable intake or physical activity. However, 91% of the intervention students …

The Influence Of Exclusive Breastfeeding On Growth Trajectory From Birth To Year 5 In A Wic Cohort, Lindsey Arevalos

Master's Theses

OBJECTIVE. The impact of exclusively breastfeeding (EBF) on child body mass index (BMI) from birth through 60 months of age was investigated.

METHODS. 60,190 mothers and children attending Women, Infant and Children (WIC) clinics in the Santa Barbara and San Luis Obispo counties of California provided data on breastfeeding duration, maternal pre-pregnancy BMI, and child weight-for-length (WL) was measured at 3 month intervals until 5 years of age. Missing time points were interpolated in determining child BMI/WL z-score trajectories plotted on the Center of Disease Control (CDC) infant and child growth curves. Multivariate analysis of variance was used to contrast …

Exploration Of Malnutrition Coding Practices At Nebraska Medicine, Frances C. Becker

Theses & Dissertations

Background: Malnutrition is present in 25-50% of hospitalized patients. Patients identified as malnourished are assigned a code based on the type and severity of malnutrition in order to gain the necessary reimbursement to care for the patients. There is a current gap in the research regarding the characteristics that define the difference between malnourished patients classified with a major complications and comorbidities (MCC) code versus a complications and comorbidities (CC) code.

Purpose: The purpose of this study was to determine which malnutrition codes are being used at Nebraska Medicine. Additionally, this study obtained clinical factors that are associated with malnutrition …

A Low-Carbohydrate Ketogenic Diet Combined With Six Weeks Of Crossfit Training Improves Body Composition And Performance, Rachel M. Gregory

Masters Theses, 2010-2019

A low-carbohydrate ketogenic diet (LCKD) is a popular approach to weight and fat loss. CrossFit is a high-intensity power training (HIPT) type exercise for all levels of age and fitness that has gained recognition as one of the fasting growing sports in America. No previous research has been found which examines body composition changes or performance in individuals consuming a LCKD and participating in CrossFit training. PURPOSE: The purpose of this research was to examine the effects of a 6-week LCKD and CrossFit program on body composition and performance. METHODS: Twenty-seven non-elite CrossFit subjects (mean ± SD age = …

Programming Heart Disease: Does Poor Maternal Nutrition Alter Expression Of Cardiac Markers Of Proliferation, Hypertrophy, And Fibrosis In Offspring?, Cathy Chun

Honors Scholar Theses

Maternal malnutrition can affect fetal organogenesis, metabolic processes, and factors involved in developmental regulation. Of the many physiological effects poor maternal nutrition can induce in offspring, one of the most important organs affected is the heart. Cardiovascular disease has been associated with poor maternal diet. It also been suggested that hypertension can originate during impaired intrauterine growth and development. Hypertension can trigger hypertensive heart disease and is associated with numerous heart complications. We hypothesized that poor maternal nutrition would alter critical growth factors associated with normal heart development, specifically, insulin-like growth factor (IGF)-1, IGF-2, transforming growth factor (TGF)β, and connective …

Using The Des-28 Tool To Determine The Relationship Among Diabetes Self-Empowerment, Diet Quality, And Glycemic Control In A Southeastern United States African American Population, Makala Katuscak Smith

Graduate Theses

No abstract provided.

The Effect Of Protein Quantity And Quality At Breakfast On Energy Metabolism, Appetite And Metabolic Health, Brianna Lynne Neumann

Graduate Theses and Dissertations

Obesity is a global health concern and, within the United States, the current obesity rate is 36% and projected to double within the next two decades. Obesity is linked to many chronic diseases such as cancer, heart disease and type 2 diabetes. In young females, weight gain (5-11 kg) between the ages of 20-30 years increases the risk of developing type 2 diabetes and cardiovascular disorders later in life. The cause of obesity is multifactorial in nature, however fundamentally weight gain occurs when energy intake is greater than energy expended (i.e. calories in > calories out). Therefore, identifying and validating nutritional …

Evaluation Of Protein Source At Breakfast On Energy Metabolism, Metabolic Health, And Food Intake: A Pilot Study, Lauren A. Cambias

Human Nutrition and Hospitality Management Undergraduate Honors Theses

Abstract

Over 30% of adults in the US are obese. A primary contributor to obesity is an unhealthy diet related to imbalanced macronutrients. Diets higher in protein (PRO) are associated with increased energy expenditure (EE) and reduced food intake. The objective of this pilot study was to determine if protein source at breakfast influences EE in young men (n=4; ages 18-35). Participants consumed three isocaloric (whey (WP), pea (PP), beef (BP); 275 kcal, 62% PRO, 23% CHO, 15% Fat) drinks in randomized, crossover design with a one-week washout period. Each test day EE, appetite, and cravings were assessed at 0, …

Awareness Of Biological Mechanisms Of Artificial Sweeteners And The Effects Of Increased Awareness Via Video Media On Intent To Change Dietary Habits In Traditional College-Age Students, Cassie A. Mahler

Honors Theses

In the past, artificial sweeteners have been touted as weight loss solutions because they theoretically do not interact with the body’s metabolism. However, new research is being done to test this theory, but what is the public awareness of these compounds’ interactions with the body? The purpose of this study is threefold: to assess the current awareness of the biological mechanisms of artificial sweeteners in traditional college-age individuals; to assess the effectiveness of video education in increasing this awareness; and to assess how the increase of this awareness might lead to intentions to change dietary habits. The study consisted of …

The Effect Of The Expanded Food And Nutrition Education Program On Participants’ Diet Quality: Does Supermarket Access Matter?, Rachel Ann Spencer

Graduate Theses and Dissertations

This project assesses the effectiveness of the Expanded Food and Nutrition Education Program (EFNEP) within the context of supermarket access. EFNEP is a national community nutrition education program that strives to give participants the tools to live healthier lives. Analysis was performed on participants from 16 Arkansas counties that completed EFNEP during 2013 or 2014. The program outcome is measured in terms of the change in Healthy Eating Index (HEI) as calculated from 24-hour diet recalls at program entry and exit. Supermarket locations were obtained from the USDA Food Nutrition Service’s SNAP Retail Locator and represent the food environment near …

The Effect Of Transformed Escherichia Coli On The Mouse Intestine Microbiome: The Microbial Metabolic Enhancement Hypothesis, Bryar P. Kader

Senior Honors Theses

Metabolic disorders affect around thirty-four percent of the population in the United States. Among these disorders is lactose intolerance, which results from diminished production of the human lactase enzyme. This disorder and others like it are genetically determined and cannot be cured. However, the use of transformed bacteria implanted in the colon may provide a means by which the faulty pathway can be bypassed. To test whether transformed bacteria have the capability to aid in the digestion of normally indigestible compounds, a transformed strain of Escherichia coli overexpressing the beta-galactosidase enzyme encoded by the lacZ gene was colonized in the …

Hydration Status, Habits, And Knowledge Of Collegiate Cross Country Runners, Laura J. Comee

Celebrating Scholarship & Creativity Day (2011-2017)

Abstract: Dehydration exceeding 2% loss of body mass can cause decreased cognitive and physical performance in endurance athletes. While many runners carry water bottles with them, most do not know their sweat rate or fluid recommendations, increasing the risk for heat-related illnesses such as heat stroke. Purpose: To assess hydration status, habits, and knowledge of collegiate cross country runners. Methods: Institutional Review Board approval was obtained and subjects completed informed consents. Thirty-three female and twenty-five male Division III collegiate runners participated in the study. Hydration status was assessed measuring the specific gravity of three urine samples one each …

Habituation Rate To Foods Of Differing Fat And Sugar Content In Healthy Weight Women, Stephanie N. Eddy

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

Objectives:

This study examined habituation rates to foods high and low in sugar and fat, and investigated the relationship between food addiction (FA) scores and habituation rates.

Methods:

A one-group, within-subjects factor design (dried apricots [low in fat and sugar] and chocolate cake [high in fat and sugar]) was used. Participants played a computer task, which assesses habituation, for food points, with sessions counter-balanced by food. The computer task has 12, 2-minute trials, in which points for 75 kcal of food can be earned. The task is programmed at a variable interval of 120 ± 42 seconds reinforcement schedule (i.e., …

Current And Past Menstrual Status Is An Important Determinant Of Femoral Neck Geometry In Exercising Women, Rebecca J. Mallinson, Nancy I. Williams, Jenna C. Gibbs, Karsten Koehler, Heather C.M. Allaway, Emily Southmayd, M. J. De Souza

Department of Nutrition and Health Sciences: Faculty Publications

Menstrual status, both past and current, has been established as an important determinant of bone mineral density (BMD) in young exercising women. However, little is known regarding the association between the cumulative effect of menstrual status and indices of bone health beyond BMD, such as bone geometry and estimated bone strength.

Purpose: This study explores the association between cumulative menstrual status and indices of bone health assessed using dualenergy x-ray absorptiometry (DXA), including femoral neck geometry and strength and areal BMD (aBMD), in exercising women.

Methods: 101 exercising women (22.0 ± 0.4 years, BMI 21.0 ± 0.2 kg/m2, 520±40 min/week …