Applied Mathematics Commons^™

A Class Of Game-Theoretic And Fokker-Planck Optimal Control Frameworks In Colon And Esophageal Cancer, Mesfer Alajmi Phd

Mathematics Dissertations - Archive

In this dissertation, we first present a new stochastic framework for parameter estimation and uncertainty quantification in colon cancer-induced immune responses. A stochastic process that captures the system's inherent randomness determines the dynamics of colon cancer. The stochastic framework is based on the Fokker-Planck equation, which represents the evolution of the probability density function corresponding to the stochastic process. We formulate an optimization problem that takes individual patient data with randomness present and solves it to obtain the unknown parameters corresponding to the individual tumor characteristics. Furthermore, we perform a sensitivity analysis of the optimal parameter set to identify the …

Batch Culture Models Of The Murine Gut Microbiome & The Impact Of Simple Dormancy On Dormancy-Capable Microorganisms Models, Ana C. Mendez

Mathematics Dissertations - Archive

The proposed mathematical biology research utilizes mathematical models to gain insight into biological systems. These systems of ordinary differential equations model diverse topics, ranging from gut microbiomes to harmful algal blooms. A complete stability analysis, supporting phase plane portraits, bifurcation diagrams, and numerical simulations will accompany the models presented. In Chapter 2, the murine gut microbiome is modeled to match laboratory experiments in the literature. In these experiments, mice eat plasmid-carrying “donor” bacteria and naturally carry plasmid-free “resident” bacteria in their gut. The models aim to capture the behavior of plasmids, donor bacteria, and resident bacteria. Chapter 3 explores dormancy …

The Computational Search For Unidentified Central Configurations Of The Newtonian N-Body Problem, Hannah G. Havel

CURE Proceedings

The N-body problem is a field of study in mathematics and physics that involves predicting the motion of particles moving under their mutual gravitational attraction. It is vital in celestial mechanics, such as planning collision-free satellite orbit trajectories. When beginning to understand the N-body problem, we can start by looking at equal masses of these particles or celestial bodies. As particles move, their position and velocity change, both energy and angular momentum are conserved. Sets of constant energy and angular momentum, known as integral manifolds, are higher-dimensional figures that represent constraints of movement to a system. Integral manifolds are described …

Advanced Techniques In Time Series Forecasting: From Deterministic Models To Deep Learning, Xue Bai

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation discusses three instances of temporal prediction, applied to population dynamics and deep learning.

In population modeling, dynamic processes are frequently represented by systems of differential equations, allowing for the analysis of various phenomena. The first application explores modeling cloned hematopoiesis in chronic myeloid leukemia (CML) via a nonlinear system of differential equations. By tracking the evolution of different cell compartments, including cycling and quiescent stem cells, progenitor cells, differentiated cells, and terminally differentiated cells, the model captures the transition from normal hematopoiesis to the chronic and accelerated-acute phases of CML. Three distinct non-zero steady states are identified, representing …

Investigation Of Space Charge Effects On Co2 Electrocatalytic Reduction On Gd-Doped Ceria Via Scanning Kelvin Probe And Model-Based Bayesian Analysis, Alejandro Mejia

Graduate Theses, Dissertations, and Problem Reports (ETD)

In studying novel energy conversion and storage systems, such as high-temperature electrolysis, numerous underlying fundamental physical processes remain unclear or inadequately understood. Among these, the modeling and comprehension of surface reaction mechanisms, coupled with the intricate effects of space‑charge interfaces, remains an unclear and challenging area of research.

The work of this dissertation involves the development of a 2D finite element analysis model, leveraging the robust MOOSE framework from INL. This model, featuring inhomogeneous defect thermodynamics for near-surface chemistry, formulated through Poisson‑Cahn variational theory, has been exploited for studying the electrocatalytic reduction of CO₂ on gadolinia doped ceria. The …

Adaptive Neh With Constrained Nearest Neighbor Subtours For The Electric Vehicle Routing Problem With Time Windows, Andrew Struthers

All Master's Theses

The development of electric vehicles is currently considered one of the most innovative areas in manufacturing. Largely driven by the desire to reduce greenhouse emissions, electric vehicles are seen as a viable alternative to internal combustion engine cars. Starting from consumer cars, a dedicated effort is being made to translate this into commercial vehicles for freight and delivery. This research introduces a novel adaptive Nawaz, Enscore, Ham (NEH) algorithm with constrained nearest neighbor subtour (NEH-NN). This algorithm is tested on the standard benchmark problems in literature and used as a seed solution for the Genetic Algorithm (GA). The performance and …

A Comparative Analysis Of A Family Of Advanced Iterative Optimization Methods In Nonlinear Regression, Tanmoy Kumar Debnath

College of Graduate Studies: Theses & Dissertations

Classical statistical supervised learning optimization techniques like the Gauss-Newton Iterative Method (GNIM), Weighted Gauss-Newton Iterative Method (WGNIM), Reweighted Gauss-Newton Iterative Method (RGNIM), and Levenberg-Marquart (LM) algorithm extend the nonlinear least squares method. The WGNIM improves model fitting by controlling heteroscedasticity in the linear and nonlinear models. A comparative analysis of the GNIM, WGNIM, RGNIM, and LM methods for fitting nonlinear models is presented. A step-wise diagnosis for structural multicollinearity in the reweighted linearized model is investigated via the Variance Inflation Factor (VIF) to determine variance inflation in the sequence of estimators for the model parameters. Under restricted multicollinearity levels in …

Mathematical Modeling Of Coupled Heat And Mass Transfer In Metal-Hydride Hydrogen Storage Systems, Muhammad Hasnain

College of Graduate Studies: Theses & Dissertations

As a promising clean energy carrier hydrogen has recently gained significant interest, but its efficient and safe storage is a major challenge. Compared to the gaseous state and liquid state, metal hydrides (MH) offer a potentially more effective storage approach for hydrogen. However, the main challenge in this approach is the low thermal conductivity of the MH bed that leads to low heat transfer and ultimately to higher charging and discharging times. The purpose of this work is to develop an in-house comprehensive heat and mass transfer model for hydrogen sorption in MH reactors to simulate the dynamic behavior of …

Bringing Gans To Medieval Times: Manuscript Translation Models, Tonilynn M. Holtz

College of Graduate Studies: Theses & Dissertations

The Generative Adversarial Networks (GAN) recently emerged as a powerful framework for producing new knowledge from existing knowledge. These models aim to learn patterns from input data then use that knowledge to generate output data samples that plausibly appear to belong to the same set as the input data. Medieval manuscripts study has been an important research area in the humanities field for many decades. These rare manuscripts are often times inaccessible to the general public, including students in scholars, and it is of a great interest to provide digital support (including, but not limited to translation and search) for …

Echolocation On Manifolds, Kerong Wang

Honors Theses

We consider the question asked by Wyman and Xi [WX23]: ``Can you hear your location on a manifold?” In other words, can you locate a unique point x on a manifold, up to symmetry, if you know the Laplacian eigenvalues and eigenfunctions of the manifold? In [WX23], Wyman and Xi showed that echolocation holds on one- and two-dimensional rectangles with Dirichlet boundary conditions using the pointwise Weyl counting function. They also showed echolocation holds on ellipsoids using Gaussian curvature.

In this thesis, we provide full details for Wyman and Xi's proof for one- and two-dimensional rectangles and we show that …

The Precedence-Constrained Quadratic Knapsack Problem, Changkun Guan

Honors Theses

This thesis investigates the previously unstudied Precedence-Constrained Quadratic Knapsack Problem (PC-QKP), an NP-hard nonlinear combinatorial optimization problem. The PC-QKP is a variation of the traditional Knapsack Problem (KP) that introduces several additional complexities. By developing custom exact and approximate solution methods, and testing these on a wide range of carefully structured PC-QKP problem instances, we seek to identify and understand patterns that make some cases easier or harder to solve than others. The findings aim to help develop better strategies for solving this and similar problems in the future.

Beyond Cryptic Equations: Reimagining Concepts In Physics Through Metaheuristics And Fantasy Stories Using Neutrosophic Venn Diagram, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Physics, the grand narrative of the universe, bas long been viewed as realm of cold, hard equations. But what if we looked beyond the formulas and considered a more imaginative origin for some of its concepts? This article explores the intriguing possibility that physics, and even cosmology, might share a surprising kinship with metaheuristics and fantastical fiction.

Ermakov Equations Can Be Derived From Zel’Dovich Pancake, And They Are Cold And Nonlocal Through Using Neutrosophic Venn Diagram, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

As we argue in a previous article, the labyrinthine worlds of Jorge Luis Borges are more than captivating narratives; they are portals to a deeper understanding of existence. By weaving elements of science-fiction fantasy with philosophical and ethical inquiries, Borges's short stories bridge the seemingly disparate realms of physics and the humanities, offering fertile ground for contemporary physics research. The present-day universe consists of galaxies, galaxy clusters, one-dimensional filaments and two-dimensional sheets or pancakes, all of which combine to form the cosmic web. The so called ”Zeldovich pancakes”, are very difficult to observe, because their overdensity is only slightly greater …

New Trends In Neutrosophic Theories And Applications, Volume Iii, Florentin Smarandache, Surapati Pramanik

Branch Mathematics and Statistics Faculty and Staff Publications

The field of neutrosophic set theory and its applications has been rapidly expanding, particularly since the introduction of the journal "Neutrosophic Sets and Systems." New theories, techniques, and algorithms are being developed at a very high rate. One of the most notable trends in neutrosophic theory is its hybridization with other set theories such as rough set theory, bipolar set theory, soft set theory, hesitant fuzzy set theory, and more. Various hybrid structures like rough neutrosophic sets, neutrosophic soft set, single valued neutrosophic hesitant fuzzy sets, among others, have been proposed in a short period. Neutrosophic sets have proven to …

Combined Plithogenic Hypersoft Sets In Decision Making On Supplier Selection With Different Mcdm Approaches., Sikkanan Sudha, Ravi Priya, Nivetha Martin, Said Broumi, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Decision making methods integrated with Plithogenic sets are highly feasible and resilient in designing optimal solutions. This research work identifies the research gaps of limited applications of combined plithogenic hypersoft sets (CPHSS) and hence proposes a supplier selection decision problem with an integrated approach combining CPHSS with MCDM methods. A generalized form of Plithogenic accuracy function is used in determining the plithogenic accuracy matrix to which the prominent ranking methods of TOPSIS, ELECTRE, VIKOR and MAIRCA are applied. The proposed hybrid decision approach is illustrated using supplier selection decision problem as a case study. The ranking results are compared with …

Logical Pluralism And Neutrosophy: Reflections On The Nature Of Truth, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The article explores the shift from classical binary logic (true and false) to a more complex landscape of logical frameworks. It introduces logical pluralism, which suggests that no single, universally accepted system of logic exists. The paper connects this idea to neutrosophy, a framework that extends fuzzy logic by incorporating a third value: indeterminacy. This triadic approach, where every proposition has a degree of truth (T), falsity (F), and indeterminacy (I), is particularly useful for managing incomplete or contradictory information. The author argues that different logical systems, like different tools, are suited for different problems, and that the …

Associated A Nexus With A Treesoft Sets And Vice Versa, Akbar Rezae, Karim Ghadimi, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

We recall the definitions of a nexus and a TreeSoft Set, and investigate the relation between them. We associated a nexus with a TreeSoft Set induced by a tree graph and vice versa.

An Innovative Approach On Yao’S Three-Way Decision Model Using Intuitionistic Fuzzy Sets For Medical Diagnosis, Wajid Ali, Tanzeela Shaheen, Iftikhar Ul Haq, Florentin Smarandache, Hamza Ghazanfar Toor, Faiza Asif

Branch Mathematics and Statistics Faculty and Staff Publications

In the realm of medical diagnosis, intuitionistic fuzzy data serves as a valuable tool for representing information that is uncertain and imprecise. Nevertheless, decision-making based on this kind of knowledge can be quite challenging due to the inherent vagueness of the data. To address this issue, we employ power aggregation operators, which prove effective in combining several sources of data, such as expert thoughts and patient information. This allows for a more correct diagnosis; a particularly crucial aspect of medical practice where precise and timely diagnoses can significantly impact medication policy and patient results. In our research, we introduce a …

A New Mood’S Median Test For Imprecise Data, Abdulrahman Alaita, Muhammad Aslam, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The existing Mood’s median test is a non-parametric test used to compare two or more sample data sets whether they are from the same population or not. There can be no application of this test to uncertain and indeterminate data. Therefore, it is necessary to find a generalization of this test that will enable us to apply it in uncertain environments. This study will present a new approach that utilizes neutrosophic statistics to apply Mood’s median test. The approach involves defining hypotheses, determining a decision rule, and performing the test in an uncertain environment. An evaluation of the performance of …

Pitching The Use Of Squared And Interaction Terms In Regression Via Baseball Heat Maps, Lucas Chepelsky

Williams Honors College, Honors Research Projects

This project will examine the impact of using second-order terms in regression. For illustration, we use an example of regression where a baseball player's three by three heat map, including the height and distance from inside to outside of the pitch, are variables used to predict batting average. We find that second-order terms are crucial in discovering nonlinear relationships and interaction effects in regression models, and maintain that the common practice of using first-order additive models is insufficient.