Applied Mathematics Commons^™

Les-C Turbulence Models And Fluid Flow Modeling: Analysis And Application To Incompressible Turbulence And Fluid-Fluid Interaction, Kyle J. Schwiebert

Dissertations, Master's Theses and Master's Reports

In the first chapter of this dissertation, we give some background on the Navier-Stokes equations and turbulence modeling. The next two chapters in this dissertation focus on two important numerical difficulties arising in fluid flow modeling: poor mass-conservation and nonphysical oscillations. We investigate two different formulations of the Crank-Nicolson method for the Navier-Stokes equations. The most attractive implementation, second order accurate for both velocity and pressure, is shown to introduce non-physical oscillations. We then propose two options which are shown to avoid the poor behavior. Next, we show that grad-div stabilization, previously assumed to have no effect on the target …

Explicit Proximal Gradient Methods: Bridging Theory And Practice In Optimization, Cassandra Mohr

Graduate Research Theses & Dissertations

Convex optimization problems are central to numerous fields, including machine learning, signal processing, and image reconstruction. The development and analysis of algorithms for solving splitting optimization problems constitutes a significant area of research. In particular, we investigate a proximal gradient splitting method (PGM) with an explicit linesearch for finding the solution of nonsmooth optimization problems, where the objective function is the sum of two convex functions.

We focus on cases where one of the functions is differentiable, without imposing any Lipschitz continuity assumption on its gradient. We establish the proper definition of the linesearch, and demonstrate that this version of …

Optimizing Microbe-Infected Mosquito Release: A Stochastic Model For Malaria Prevention, Steeven Belvinos Affognon, Henri E.Z. Tonnang, Philip Ngare, Benard Kipchumba Kiplangat, Shirley Abelman, Jeremy K. Herren

All Peer-Reviewed Publications

Malaria remains a critical public health challenge in Africa, demanding innovative control strategies. This study introduces a novel approach using Microsporidia MB-infected mosquitoes and stochastic optimal control within a Lévy process framework to regulate mosquito release strategies. The primary goal is to optimize Microsporidia MB prevalence within mosquito populations to disrupt Plasmodium transmission to humans. By incorporating Lévy noise into the modeling process, we capture the inherent randomness of mosquito dynamics, improving intervention accuracy. The model, guided by the Hamilton–Jacobi–Bellman (HJB) equation, optimizes release protocols while accounting for key environmental factors like seasonality and temperature fluctuations. Results show that intervention …

Quantification Of Antiretroviral Drug Emtricitabine In Human Plasma By Surface Enhanced Raman Spectroscopy, Marguerite R. Butler, Terry A. Jacot, Sucharita M. Dutta, Gustavo F. Doncel, John B. Cooper

Chemistry & Biochemistry Faculty Publications

In this study, reproducible label-free detection and quantification of the antiretroviral drug emtricitabine (FTC) down to 78 ng/mL in human plasma by surface enhanced Raman spectroscopy (SERS) is presented. A novel plasma sample pretreatment method using silver nitrate and silver colloidal nanoparticles (Ag CNPs) was used to prepare the plasma samples for analysis. The pretreated plasma samples were evaporated to dryness on an aluminum surface and a computer-controlled Raman scanning system was used to collect spatially resolved SERS spectra of the entire surface. Calibration curves of commercial human plasma samples containing FTC in a concentration range of 5000 to 78 …

Advanced Techniques In Time Series Forecasting: From Deterministic Models To Deep Learning, Xue Bai

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation discusses three instances of temporal prediction, applied to population dynamics and deep learning.

In population modeling, dynamic processes are frequently represented by systems of differential equations, allowing for the analysis of various phenomena. The first application explores modeling cloned hematopoiesis in chronic myeloid leukemia (CML) via a nonlinear system of differential equations. By tracking the evolution of different cell compartments, including cycling and quiescent stem cells, progenitor cells, differentiated cells, and terminally differentiated cells, the model captures the transition from normal hematopoiesis to the chronic and accelerated-acute phases of CML. Three distinct non-zero steady states are identified, representing …

Simulation Of Wave Propagation In Granular Particles Using A Discrete Element Model, Syed Tahmid Hussan

College of Graduate Studies: Theses & Dissertations

The understanding of Bender Element mechanism and utilization of Particle Flow Code (PFC) to simulate the seismic wave behavior is important to test the dynamic behavior of soil particles. Both discrete and finite element methods can be used to simulate wave behavior. However, Discrete Element Method (DEM) is mostly suitable, as the micro scaled soil particle cannot be fully considered as continuous specimen like a piece of rod or aluminum. Recently DEM has been widely used to study mechanical properties of soils at particle level considering the particles as balls. This study represents a comparative analysis of Voigt and Best …

Linear Topological Space, Vi Nguyen

UNF Graduate Theses and Dissertations

This thesis begins with an introduction to linear and topological spaces and then defines linear topological spaces. It studies key properties such as neighborhoods, convexity, reflexivity, and weak and weak* topologies. Finally, it concludes with solving non-linear partial differential equations.

Penalized Interpolating B-Splines And Their Applications, Kylee L. Hartman-Caballero

Theses and Dissertations

One of the most studied data analysis techniques in Numerical Analysis is interpolation. Interpolation is used in a variety of fields, namely computer graphic design and biomedical research. Among interpolation techniques, cubic splines have been viewed as the standard since at least the 1960s, due to their ease of computation, numerical stability, and the relative smoothness of the interpolating curve. However, cubic splines have notable drawbacks, such as their lack of local control and necessary knowledge of boundary conditions. Arguably a more versatile interpolation technique is the use of B-splines. B-splines, a relative of Bézier curves, allow local control through …

Mathematical Modeling And Analysis Of Inflammation And Tissue Repair: Lung Inflammation And Wound Healing In Corals Under Stress, Quintessa Hay

Theses and Dissertations

A variety of insults, including tissue injury and/or exposure to pathogen, elicit an immune response in many organisms. An improperly regulated immune response can result in deleterious effects to the organism. Here we present models for lung injury in young and old mice and models for wound healing in coral reefs.

It is well known that the immune response becomes less effective in older individuals. This is of particular interest in pulmonary insults such as ventilator induced lung injury (VILI) or lung infection. We extended a mathematical model for the inflammatory response to VILI and used experimental data to select …

Mathematical Analysis Of Eukaryotic Pericentromere, Puranjan Ghimire

Theses and Dissertations

The centromere is crucial for chromosomal stability and their proper segregation during cell division in eukaryotes. Surrounding the centromere are pericentromeres, made of repetitive DNA elements called pericentromeric repeats, varying from 10 in fission yeast to thousands in humans. These repeats form densely packed heterochromatin, where genes are usually silenced. The silencing mechanism across different pericentromeric repeats remains unclear.

Despite variations in sequence and length, pericentromeric repeats are conserved across eukaryotes, indicating their functional importance. This dissertation presents mathematical models to quantify gene silencing in fission yeast and humans. In fission yeast, my model predicts that silencing occurs only with …

Mathematical Modeling Of Phage-Bacteria Population Dynamics, John Lawrence D. Palacios

Theses and Dissertations

Bacteriophages are viruses that infect and replicate within bacteria. Lytic phages cause the bacterial cell to burst, killing the bacteria. These types of phages can be used to treat patients with antibiotic-resistant bacterial infections. As a step in developing successful treatment protocols, we aim to understand the population dynamics of phages and bacteria using an in vitro model. We model the dynamics using the Campbell model, which consists of a delay differential equation (DDE), as a base model. We extended the model by including the emergence of phage resistance. We then compared the DDE model with a parallel ordinary differential …

Long-Wave Modeling Of Viscous Film Dynamics Inside A Tube With Time-Dependent Radius, Robert E. Hicks

Theses and Dissertations

Lung fluid dynamics is a well studied topic and relevant in the field of research surrounding patients with Chronic Obstructive Pulmonary Disease (COPD) and cystic fibrosis. However, the literature on the mathematical description of the net pulmonary fluid transport in the case of constricting and expanding airways is scarce. In this paper we aim to address how breathing contributes to airways clearance in patients with pulmonary diseases such as COPD and CF in which cilia do not function properly. We begin with the flow of a fluid-filled tube with rigid walls of fixed radius and the effects of gravity being …

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …

Last Passage Time And Excursion Theory For Solvable Diffusions With Applications In Mathematical Finance, Yaode Sui

Theses and Dissertations (Comprehensive)

In this dissertation, we investigate the properties of last passage times and excursion theory in one-dimensional solvable diffusions, emphasizing their applications in financial modeling, particularly in option pricing. We derive closed-form formulas for the marginal distribution of last passage times and their joint distribution with process values, including the maximum and minimum of the process value. The focus is on time-homogeneous diffusions with various boundaries and imposed killing. Employing spectral expansion theory, we derive explicit formulas for distributions of last passage times in common processes such as Drifted Brownian Motion (BM), Squared Bessel (SQB), Ornstein-Uhlenbeck (OU), and Cox-Ingersoll-Ross (CIR) models. …

Artificial Intelligence- Driven Fvm-Ann Model For Entropy Analysis Of Mhd Natural Bioconvection In Nanofluid-Filled Porous Cavities, N. Elsedais, M. A. Mansour, A. M. Aly, Sara Abdelsalam

Basic Science Engineering

No abstract provided.

Optimizing Energy Consumption In Smart Homes Using Ga-Lstm, Akibor Junior Chukwuka, Bakare-Bolaji Moyosoreoluwa, Baboucarr Dibba

School of Mathematical & Statistical Sciences Faculty Publications

The need to optimize energy consumption arises from the inadequate energy supply many homes face. However, to optimize energy consumption in a home, one must be equipped with the knowledge of the energy consumption rate and energy supply rate in the home. This paper proposed the use of a Long Short-Term Memory (LSTM) model optimized by Genetic Algorithm (GA) to optimize the energy consumption in a smart home. The model was designed using 8 input variables, which were observed weather information of a given region over a span of 350 days. The data set was split into a training data …

Analyzing A Smartphone Battle Using Bass Competition Model, Maila Hallare, Alireza Hosseinkhan, Hasala Senpathy K. Gallolu Kankanamalage

CODEE Journal

Many examples of 2x2 nonlinear systems in a first-course in ODE or a mathematical modeling class come from physics or biology. We present an example that comes from the business or management sciences, namely, the Bass diffusion model. We believe that students will appreciate this model because it does not require a lot of background material and it is used to analyze sales data and serve as a guide in pricing decisions for a single product. In this project, we create a 2x2 ODE system that is inspired by the Bass diffusion model; we call the resulting system the Bass …

Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia

Journal of Nonprofit Innovation

Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.

Imagine Doris, who is …

Simulation Of Multi-Variable Converters Using The Linear Interpolation Method, Miraziz Vorisovich Sagatov

Chemical Technology, Control and Management

In this work, based on the theory of barycentric coordinates and simplexes, a linear interpolation method is proposed for modeling and controlling the operation of multiparameter converters. It has been determined that the linear interpolation method minimizes the structural diagram of a computing device, which makes it possible to more accurately determine the metrological characteristics of multiparameter measuring transducers and offer effective methods and means for processing primary measurement information. A theorem has been proven about a linear interpolating polynomial of a function of many variables, which will allow us to judge the property of linearization of multidimensional quantities from …

Modeling The Population Dynamics And Movement Of Zebra Mussels, Alexanderia Lacy, Yu Jin, David Strayer, Suzanne Lenhart

Department of Mathematics: Faculty Publications

Zebra mussels have caused significant damage in many lakes and rivers. By using a hybrid population model with discrete-time equations and ordinary differential equations, we represent the zebra mussel’s life cycle, growth, and population movement. The dynamics of the larvae (unsettled and settled larvae) are represented during the summer months in a system of two ordinary differential equations, while the juvenile, small adult, and large adult stages are represented by a discrete model with yearly time steps. The goal is to investigate the effects of zebra mussel movement between three different spatial locations and possible control measures. Zebra mussel data …