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Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen 2024 Wilfrid Laurier University

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …


Thermodynamic Laws Of Billiards-Like Microscopic Heat Conduction Models, Ling-Chen Bu 2023 University of Massachusetts Amherst

Thermodynamic Laws Of Billiards-Like Microscopic Heat Conduction Models, Ling-Chen Bu

Doctoral Dissertations

In this thesis, we study the mathematical model of one-dimensional microscopic heat conduction of gas particles, applying both both analytical and numerical approaches. The macroscopic law of heat conduction is the renowned Fourier’s law J = −k∇T, where J is the local heat flux density, T(x, t) is the temperature gradient, and k is the thermal conductivity coefficient that characterizes the material’s ability to conduct heat. Though Fouriers’s law has been discovered since 1822, the thorough understanding of its microscopic mechanisms remains challenging [3] (2000). We assume that the microscopic model of heat conduction is a hard ball system. The …


Utilizing Non-Negative Least Squares For Data-Driven Discovery Of Dynamics, Tracey G. Oellerich 2023 George Mason University

Utilizing Non-Negative Least Squares For Data-Driven Discovery Of Dynamics, Tracey G. Oellerich

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, Arkaprovo Ghosal, Padmanabhan Seshaiyar Dr., Adriana Dawes Dr., General Genomics Inc. 2023 George Mason University

Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, Arkaprovo Ghosal, Padmanabhan Seshaiyar Dr., Adriana Dawes Dr., General Genomics Inc.

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Understanding Impact Of Educational Awareness And Vaccines As Optimal Control Mechanisms For Changing Human Behavior In Disease Epidemics, Manal Badgaish, Dr. Padmanabhan Seshaiyer 2023 George Mason University

Understanding Impact Of Educational Awareness And Vaccines As Optimal Control Mechanisms For Changing Human Behavior In Disease Epidemics, Manal Badgaish, Dr. Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Parameter Estimation In Epidemiological And Climate Models Using Ensemble Smoothing With Multiple Data Assimilation, Emmanuel Fleurantin 2023 George Mason University

Parameter Estimation In Epidemiological And Climate Models Using Ensemble Smoothing With Multiple Data Assimilation, Emmanuel Fleurantin

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Thoracoabdominal Asynchrony In A Virtual Preterm Infant: Computational Modeling And Analysis, Richard R. Foster, Bradford Smith, Laura Ellwein Fix 2023 Virginia Commonwealth University

Thoracoabdominal Asynchrony In A Virtual Preterm Infant: Computational Modeling And Analysis, Richard R. Foster, Bradford Smith, Laura Ellwein Fix

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling Single And Multiple Pacemaker Interaction In Jellyfish Locomotion, Alexander Hoover 2023 Illinois State University

Modeling Single And Multiple Pacemaker Interaction In Jellyfish Locomotion, Alexander Hoover

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Minimization Of Diet For Optimum Consumption Using Linear Programming, Nita Ngozi Ezekwem, Aditi Ghosh 2023 Texas A&M University-Commerce

Minimization Of Diet For Optimum Consumption Using Linear Programming, Nita Ngozi Ezekwem, Aditi Ghosh

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Helices In Fluids And Applications To Modeling In Biology, Eva M. Strawbridge 2023 James Madison University

Helices In Fluids And Applications To Modeling In Biology, Eva M. Strawbridge

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Lnksc Method On Pde-Constrained Optimization For Mcf-7 Breast Cancer Cell Growth Predictions And Treatment Response With Gold Nanoparticles, WIDODO SAMYONO, Shakhawat Bhuiyan 2023 Jarvis Christian College

Lnksc Method On Pde-Constrained Optimization For Mcf-7 Breast Cancer Cell Growth Predictions And Treatment Response With Gold Nanoparticles, Widodo Samyono, Shakhawat Bhuiyan

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Disease Informed Neural Network And Mathematical Modeling Of Covid-19 With Human Behavior Modification, Alonso Gabriel Ogueda, Jeremis Morales-Morales, Carmen Caiseda, Padmanabhan Seshaiyer 2023 George Mason University

Disease Informed Neural Network And Mathematical Modeling Of Covid-19 With Human Behavior Modification, Alonso Gabriel Ogueda, Jeremis Morales-Morales, Carmen Caiseda, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Physics-Informed Neural Networks For Agent-Based Epidemiological Model Calibration, Alvan C. Arulandu, Padmanabhan Seshaiyer 2023 Harvard University

Physics-Informed Neural Networks For Agent-Based Epidemiological Model Calibration, Alvan C. Arulandu, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling The Communication Dynamics In Human-Autonomy Teams: Insights From Search And Rescue Scenarios, Carlos E. Bustamante Orellana, Lucero Rodriguez Rodriguez, Yun Kang 2023 Arizona State University at the Tempe Campus

Modeling The Communication Dynamics In Human-Autonomy Teams: Insights From Search And Rescue Scenarios, Carlos E. Bustamante Orellana, Lucero Rodriguez Rodriguez, Yun Kang

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Modeling Of The Impact Of Lobbying On Climate Policy, Andrew Jacoby, Claire Hannah, James Hutchinson, Jasmine Narehood, Aditi Ghosh, Padmanabhan Seshaiyer 2023 Jack M Barrack Hebrew Academy

Mathematical Modeling Of The Impact Of Lobbying On Climate Policy, Andrew Jacoby, Claire Hannah, James Hutchinson, Jasmine Narehood, Aditi Ghosh, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Computational Study Of Twin Circular Particles Settling In Fluid Using A Fictitious Boundary Approach, Imran Abbas, Kamran Usman 2023 Department of Mathematics, Air University, PAF Complex, Islamabad 44000, Pakistan

Computational Study Of Twin Circular Particles Settling In Fluid Using A Fictitious Boundary Approach, Imran Abbas, Kamran Usman

International Journal of Emerging Multidisciplinaries: Mathematics

The objective of this study is to examine the performance of two adjacent solid particles as they settle in close nearness, with a focus on comprehending the intricate interactions between the particles and the surrounding fluid during the process of sediment transport. Simulations are conducted with different initial horizontal spacing between particles and Reynolds numbers (Re). The findings of the simulations highlight the impact of the initial spacing between particles and Reynolds numbers (Re) as key factors influencing the ultimate settling velocity and separation distance. In general, when the initial spacing between particles is small and the Reynolds number (Re) …


Modeling Nonsegmented Negative-Strand Rna Virus (Nnsv) Transcription With Ejective Polymerase Collisions And Biased Diffusion, Felipe-Andres Piedra 2023 Baylor College of Medicine

Modeling Nonsegmented Negative-Strand Rna Virus (Nnsv) Transcription With Ejective Polymerase Collisions And Biased Diffusion, Felipe-Andres Piedra

Research Symposium

Background: The textbook model of NNSV transcription predicts a gene expression gradient. However, multiple studies show non-gradient gene expression patterns or data inconsistent with a simple gradient. Regarding the latter, several studies show a dramatic decrease in gene expression over the last two genes of the respiratory syncytial virus (RSV) genome (a highly studied NNSV). The textbook model cannot explain these phenomena.

Methods: Computational models of RSV and vesicular stomatitis virus (VSV – another highly studied NNSV) transcription were written in the Python programming language using the Scientific Python Development Environment. The model code is freely available on GitHub: …


Time-Fractional Navier-Stokes Equation Solved By Fractional Variation Of Parameters Method: An Analytic Approach, Muhammad Shakil Shaiq, Shoaib Ali, Azeem Shahzad, Tahir Naseem 2023 Department of Mathematics, The Sahara University, Narowal, 51600 Pakistan

Time-Fractional Navier-Stokes Equation Solved By Fractional Variation Of Parameters Method: An Analytic Approach, Muhammad Shakil Shaiq, Shoaib Ali, Azeem Shahzad, Tahir Naseem

International Journal of Emerging Multidisciplinaries: Mathematics

In this investigation, we make use of the Variation of Parameters Method (VPM) to find a solution to the nonlinear time-fractional Navier-Stokes equation. Additionally, the fractional derivative in the sense of Riemann-Liouville is presented and discussed. Within the scope of this investigation, the Variation of Parameters Method (VPM) has been modified to include a fractional multiplier. The Fractional Variation of Parameters Method (FVPM) was created as an iterative way to solve the time-fractional nonlinear time-fractional Navier-Stokes equation. According to the findings of the calculations, the newly developed algorithm (FVPM) is compatible, accurate, and reliable.


An Implementation Of The Method Of Moments On Chemical Systems With Constant And Time-Dependent Rates, Emmanuel O. Adara, Roger B. Sidje 2023 University of Alabama, Tuscaloosa

An Implementation Of The Method Of Moments On Chemical Systems With Constant And Time-Dependent Rates, Emmanuel O. Adara, Roger B. Sidje

Northeast Journal of Complex Systems (NEJCS)

Among numerical techniques used to facilitate the analysis of biochemical reactions, we can use the method of moments to directly approximate statistics such as the mean numbers of molecules. The method is computationally viable in time and memory, compared to solving the chemical master equation (CME) which is notoriously expensive. In this study, we apply the method of moments to a chemical system with a constant rate representing a vascular endothelial growth factor (VEGF) model, as well as another system with time-dependent propensities representing the susceptible, infected, and recovered (SIR) model with periodic contact rate. We assess the accuracy of …


Boundary Integral Equation Methods For Superhydrophobic Flow And Integrated Photonics, Kosuke Sugita 2023 New Jersey Institute of Technology

Boundary Integral Equation Methods For Superhydrophobic Flow And Integrated Photonics, Kosuke Sugita

Dissertations

This dissertation presents fast integral equation methods (FIEMs) for solving two important problems encountered in practical engineering applications.

The first problem involves the mixed boundary value problem in two-dimensional Stokes flow, which appears commonly in computational fluid mechanics. This problem is particularly relevant to the design of microfluidic devices, especially those involving superhydrophobic (SH) flows over surfaces made of composite solid materials with alternating solid portions, grooves, or air pockets, leading to enhanced slip.

The second problem addresses waveguide devices in two dimensions, governed by the Helmholtz equation with Dirichlet conditions imposed on the boundary. This problem serves as a …


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