Veterinary Medicine Commons^™

Gabapentin, A Human Therapeutic Medication And An Environmental Substance Transferring At Trace Levels To Horses: A Case Report., Kimberly Brewer, Jacob Machin, George Maylin, Clara Fenger, Abelardo Morales-Briceño, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Gabapentin, 1-(Aminomethyl)cyclohexaneacetic acid, MW 171.240, is a frequently prescribed high dose human medication that is also used recreationally. Gabapentin is orally absorbed; the dose can be 3,000 mg/day and it is excreted essentially unchanged in urine. Gabapentin is stable in the environment and routinely detected in urban wastewater. Gabapentin randomly transfers from humans to racing horses and is at times detected at pharmacologically ineffective / trace level concentrations in equine plasma and urine. In Ohio racing between January 2019 and July 2020,18 Gabapentin identifications, all less than 2 ng/ml in plasma, were reported. These identifications were ongoing because the horsemen …

Glutathione And Glutaredoxin In Redox Regulation And Cell Signaling Of The Lens, Marjorie F. Lou

School of Veterinary and Biomedical Sciences: Faculty Publications

The ocular lens has a very high content of the antioxidant glutathione (GSH) and the enzymes that can recycle its oxidized form, glutathione disulfide (GSSG), for further use. It can be synthesized in the lens and, in part, transported from the neighboring anterior aqueous humor and posterior vitreous body. GSH is known to protect the thiols of the structural lens crystallin proteins from oxidation by reactive oxygen species (ROS) so the lens can maintain its transparency for proper visual function. Age-related lens opacity or senile cataract is the major visual impairment in the general population, and its cause is closely …

Intestinal Parasite Prevalence In Fecal Samples In Nebraska Dog Parks, Kristianna Muller

Honors Program: Senior Projects (Public)

From February to April 2022, fecal samples were collected from eight dog parks in the Omaha and Lincoln, NE areas. A total of 160 samples were collected and assessed for the presence of intestinal parasites. The zinc sulfate double centrifugal flotation technique was used to determine infection. Out of the 160 samples, ten were positive for parasite contamination (6.25% prevalence). The most observed parasites were hookworms, found in 3.75% of all samples (6/160). Cystoisospora, Giardia, Toxocara canis, and Toxascaris leonina were all found only once, for a prevalence of 0.625% each. Compared to other studies, our infection …

The Ethical Perceptions Of Dog Tail Docking Amongst Owners And Veterinarians In South Carolina, Hannah Ellen Steinberg

Senior Theses

This thesis aimed to discover, in depth, what tail docking of dogs is, why it is currently in practice, what the controversial opinions surrounding it are, how the opinions differ when taking into account the professionals of the field versus owners and breeders, and how it can be addressed in the future to treat our animals as humanely as possible.

Based on the surveying of South Carolinian owners, breeders, and veterinarians, it was discovered that dog tail-docking procedures are overwhelmingly used for cosmetic or aesthetic purposes, with the aim being to match breed standards. There was a disagreement amongst those …

Seasonal Habitat Selection By American White Pelicans, Frederick L. Cunningham, Guiming Wang, D. Tommy King

United States Department of Agriculture Wildlife Services: Staff Publications

Resource utilization strategies of avian migrants are a major concern for conservation and management. Understanding seasonal habitat selection by migratory birds helps us explain the ongoing continental declines of migratory bird populations. Our objective was to compare the secondorder and third-order habitat selection by the American White Pelican (Pelecanus erythrorhynchos; hereafter pelican) between the breeding and non-breeding grounds. We tested the Lack hypothesis that habitat selection by migratory birds is stronger on the breeding grounds than on the nonbreeding grounds. We used random-effect Dirichlet-multinomial models to estimate the second-order habitat selection between the seasons with the GPS locations …

Effects Of Early‑Life Experience On Innovation And Problem‑Solving In Captive Coyotes, Andrew C. Garcia, Mitchell A. Parsons, Julie K. Young

United States Department of Agriculture Wildlife Services: Staff Publications

Early-life experience often shapes behaviors like innovation and exploration. These behaviors are important to animals encountering novel food resources in diverse habitats, such as mesocarnivores in urban areas. To understand if early-life experiences impact later-life behavior, we examined how coyotes (Canis latrans) responded to a multi-access puzzle box at two life stages: pup (~ 7 weeks) and dispersal (~ 10 months). We first exposed pups, still living with their parents and littermates, to a baited puzzle box. At dispersal age, we again tested both these pups and an age-matched control group that was not exposed to the puzzle …

Recent Emergence Of Bovine Coronavirus Variants With Mutations In The Hemagglutinin-Esterase Receptor Binding Domain In U.S. Cattle, Aspen M. Workman, Tara G. Mcdaneld, Gregory P. Harhay, Subha Das, John Dustin Loy, Benjamin M. Hause

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine coronavirus (BCoV) has spilled over to many species, including humans, where the host range variant coronavirus OC43 is endemic. The balance of the opposing activities of the surface spike (S) and hemagglutinin-esterase (HE) glycoproteins controls BCoV avidity, which is critical for interspecies transmission and host adaptation. Here, 78 genomes were sequenced directly from clinical samples collected between 2013 and 2022 from cattle in 12 states, primarily in the Midwestern U.S. Relatively little genetic diversity was observed, with genomes having >98% nucleotide identity. Eleven isolates collected between 2020 and 2022 from four states (Nebraska, Colorado, California, and Wisconsin) contained a …

Recent Emergence Of Bovine Coronavirus Variants With Mutations In The Hemagglutinin-Esterase Receptor Binding Domain In U.S. Cattle, Aspen M. Workman, Tara G. Mcdaneld, Gregory P. Harhay, Subha Das, John Dustin Loy, Benjamin M. Hause

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine coronavirus (BCoV) has spilled over to many species, including humans, where the host range variant coronavirus OC43 is endemic. The balance of the opposing activities of the surface spike (S) and hemagglutinin-esterase (HE) glycoproteins controls BCoV avidity, which is critical for interspecies transmission and host adaptation. Here, 78 genomes were sequenced directly from clinical samples collected between 2013 and 2022 from cattle in 12 states, primarily in the Midwestern U.S. Relatively little genetic diversity was observed, with genomes having >98% nucleotide identity. Eleven isolates collected between 2020 and 2022 from four states (Nebraska, Colorado, California, and Wisconsin) contained a …

Assistance Dogs For Military Veterans With Ptsd: A Systematic Review, Meta-Analysis, And Meta-Synthesis, Sarah C. Leighton, Leanne O. Nieforth, Marguerite E. O'Haire

Purdue University Libraries Open Access Publishing Fund

Psychiatric assistance dogs for military veterans with posttraumatic stress disorder (PTSD) currently make up over 19% of assistance dog partnerships globally. We conducted a systematic review of the literature relating to these partnerships, with specific aims to (1) summarize their characteristics, (2) evaluate the quality of existing evidence, and (3) summarize outcomes. A total of 432 records were independently screened (Cohen’s kappa = 0.90). Of these, 41 articles (29 peer-reviewed publications and 12 unpublished dissertations) met inclusion criteria. Data extraction was conducted to address the research aims, including a meta-analysis (quantitative outcomes) and meta-synthesis (qualitative outcomes). All peer-reviewed publications on …

Making The Case: Adding A Social Work Perspective To A Case Study In A Veterinary Practice, Paula Gerstenblatt, Diane Rhodes, Dorothea Ivey

People and Animals: The International Journal of Research and Practice

This article describes a case study exploration of a veterinary practice from the perspective of social work. Recognizing the stressful work of veterinary providers, including compassion fatigue and high suicide rates, the current study identified both a need for and the potential role of social workers in veterinary practice. Professionals were interviewed in an emergency/specialty practice. Using the interview data, the authors built a demonstrative case that underlines the vulnerability of veterinary professionals and the potential of social work to improve the quality of their work experiences and longevity.

Understanding The Causative Agent, Pathophysiology And Management Of The Kentucky Mare Reproductive Loss Syndrome And Related Syndromes, Thomas Tobin, Gabriel Volpato, Navid Yousefi-Mashouf, Kimberly Brewer

Maxwell H. Gluck Equine Research Center Faculty Presentations

No abstract provided.

Application Of A Single-Tank Sequencing Batch Reactor For Long-Term Zebrafish Care, Aranya Ponpornpisit, Malinee Jongjaroenjai, Naowarat Suthamnatpong, Surachet Burut-Archanai

The Thai Journal of Veterinary Medicine

Sequencing batch reactors are efficient wastewater treatment systems, however, they are not adapted to treat aquaria. We aimed to compare the efficacies of a modified single-tank sequencing batch reactor (SSBR) and a regular overflow filtration system. Zebrafish were maintained in an acrylic aquarium connected to an SSBR or in a tank connected to a regular overflow filtration system for 27 weeks. Water change or aeration using air stone was not performed. The water quality in both groups was within the normal range until 26 weeks, after which the nitrite and nitrate levels increased. The average temperature was, 29.46 ± 0.71°C …

Oral Administration Of Iron And Toltrazuril In Combination Improves Survival Rate And Growth Rate And Reduces Anaemia In Piglets, Pachara Pearodwong, Padet Tummaruk

The Thai Journal of Veterinary Medicine

The present study was performed to determine the efficacy of an oral administration of iron and toltrazuril in combination on the growth rate, survival rate and the incidence of anaemia in suckling piglets. A total of 406 piglets were randomly allocated to one of three groups: i.) CONTROL (n = 161), the piglets were administered iron dextran 200 mg intramuscularly and toltrazuril (20 mg/kg) orally at 3 days of age; ii.) NEGATIVE (n = 84), the piglets were not treated with iron until 7 days of age, and toltrazuril was given at 5 days of age and iii.) TREATMENT (n …

Generation Of Tail Bearing Sperm-Like Cells From In Vitro Spermatogenesis Of Farming Goat Testis, Rakesh Bhaskar, Bijaylaxmi Sahoo, Sung Soo Han, Mukesh Kumar Gupta

The Thai Journal of Veterinary Medicine

In vitro spermatogenesis offers a therapeutic modality for the treatment of male infertility associated with pre-or post-meiotic barriers to the spermatogenesis process. The present study reports the production of tail-bearing sperm-like cells from in vitro spermatogenesis of farming goat testis in an air-liquid inter-phase culture. The testicular fragments (1-2 mm3) were placed on agarose scaffolds at air-liquid interphase and cultured in vitro for 60 days. Proliferating germ cell colonies were visible after 45-55 days of culture. Differentiation of cells to spermatogonia and spermatocytes was observed from the 40th day onwards. Tail bearing sperm-like elongated cells, with apical acrosome, were detected …

Radiographic Cardiac Indices For The Evaluation Of Cardiac And Left Atrial Sizes In Healthy Wistar Albino Rats (Rattus Norvegicus), Mehmet Alper Çeti̇nkaya, Mahir Kaya

The Thai Journal of Veterinary Medicine

This study was performed for the purpose of comparing vertebral heart score (VHS), radiographic left atrial dimension (RLAD) and vertebral left atrial size (VLAS) values derived from plain and contrast right lateral thoracic radiographs from 70 healthy, young adult Wistar albino rats and to identify reference values for these radiographic cardiac indices. Measurements were taken by two observers blinded to the study data. VHS, RLAD and VLAS median values and reference ranges were 8v and 7-9.3v for plain radiography, 8.2v and 7.4-9.5v for contrast radiography (P< 0.000), 1.3v and 1-1.8v for plain radiography, 1.3v and 1.1-1.6v for contrast radiography (P <0.000) and 1.9v and 1.4-2.4v for plain radiography and 1.95v 1.5-2.4v for contrast radiography (P<0.001), respectively. The only statistically significant difference was observed in terms of gender between VHS values from plain and contrast radiographs (P<0.02). Intraobserver and interobserver measurements revealed excellent agreement for radiographic cardiac indices obtained from contrast radiography. The study measurements indicate that contrast radiography provides a more effective quantitative assessment of cardiac and left atrial sizes than plain radiography. The radiographic cardiac index measurements presented in this study can serve as a reference baseline for both veterinarians and experimental cardiovascular studies.

Haplotype Variation Of Partial Sry Gene In Ongole Grade Bulls (Bos Indicus) Of Indonesia, Widya Pintaka Bayu Putra, Saiful Anwar, Slamet Diah Volkandari, Syahruddin Said

The Thai Journal of Veterinary Medicine

Ongole grade cattle (Bos indicus) are Indonesian beef cattle that adapt well in a tropical climate. This study was aimed to observe the genetic diversity of partial Sex-determining of the region Y chromosome (SRY) gene (625 bp) in Ongole grade bulls (Bos indicus) of Indonesia. A total twenty-three (23) DNA samples of animal studies were collected from frozen sperm (straws) produced by the National Artificial Insemination Centers (NAICs) of Lembang (13 straws) and Singosari (10 straws). Research showed that a total of four (4) insertion mutations were detected in the intronic region with the position of 1831th, 1844th, 1850th and …

Computed Tomographic Findings Of Primary Renal Tumors In Dogs And Cats, Daji Noh, Jaejin Shim, Sooyoung Choi, Hojung Choi, Youngwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

Primary renal tumor is uncommon in dogs and cats, with few previous computed tomography (CT) reports. Previous studies have reported that contrast-enhancing CT is helpful in differentiating the type of renal tumors. This study aimed to describe CT findings of renal tumors in dogs and cats and identify contrast-enhancing pattern according to 3 post-contrast phases. In this retrospective study, the following CT findings were recorded for each patient: (1) renal tumor involvement, (2) enhancement pattern, (3) vascular invasion, (4) presence of lymphadenopathy and organ metastasis, (5) presence of mineralization, and (6) attenuation values of renal tumors on pre- and post-contrast …

Surgical Removal Of Urinary Bladder Urolith In Female Asian Elephant (Elephas Maximus) By Episiotomy And Urinary Bladder Sphincterotomy, Nikorn Thongtip, Supaphen Sripiboon, Nattaphol Muangthong, Suteeranun Pipitwanichtham, Smit Srisomrun, Patcharida Dittawong, Phawaran Meetipkit, Ratiwan Sitdhibutr, Warangkhana Lankaphin, Petthisak Sombutputorn, Weerapongse Tangjitjaroen

The Thai Journal of Veterinary Medicine

A 50-year-old female Asian elephant (Elephas maximus) was referred to the Kasetsart University Veterinary Teaching Hospital with histories of anuria and abdominal pain for five days. Trans-rectal ultrasonography demonstrated the presence of hyperechogenic uroliths located between the neck and trigone of the urinary bladder. Vestibuloscopy by endoscope revealed an abnormal brownish mass obstructing the internal bladder orifice. Episiotomy was performed after standing sedation with dexmedetomidine, epidural anesthesia and perineal infiltration with lidocaine. A single 1.7 kg urinary bladder urolith with 17x12x10 cm dimension was manually removed using a combination of several methods, including sphincter dilatation using lidocaine ring infiltration at …

Microbial Diversity And Microbiological Quality Of Edible-Birdnest (Ebn) During Processing And Storage, Shazreena Zuber, Zunita Zakaria, Jalila Abu, Saleha Abdul Aziz

The Thai Journal of Veterinary Medicine

The microbial quality of 45 EBN consisting of raw unclean and raw clean Edible-birdnest (EBN) from two different premises were analyzed for 8 weeks. Using 3M™ Petrifilm, Total Aerobic Count (TAC) of raw clean EBN and Total Coliform Count (TCC) for raw unclean, 3 days, 2 weeks and 4 weeks EBN in both premises exceeded the limit stated in by the Malaysian Standard (MS 2334:2011; SIRIM/DVS 3:2015). A total of 264 bacteria and 208 fungi species were isolated. Bacteria isolated was identified using bioMérieux’s API® kit and a series of biochemical tests. Fungi were identified using techniques described by the …

Odor Detection Of Cancer Cell Metabolites By Scent-Detection Dogs, Geontae Park, Dongwook Kim, Seongsoo Jeong, Dongsun Park, Gonhyung Kim

The Thai Journal of Veterinary Medicine

Dogs have a superior olfactory system; thus, they have been trained and used to detect various nonbiological and biological scents. In addition, many studies have recently reported dogs’ ability to detect the odor of certain cancers or cancer cells. A previous study documented that a dog trained to detect a certain malignant cancer cell could also detect another, unfamiliar malignant cancer cell well, implying that these two cancer cells share a certain specific odor. Thus, given the hypothesis that malignant cancer cells of different origins may contain a common cancer-specific odor, the purpose of the present study was to evaluate …