Open Access. Powered by Scholars. Published by Universities.®

Small or Companion Animal Medicine Commons

Open Access. Powered by Scholars. Published by Universities.®

1,272 Full-Text Articles 1,909 Authors 279,911 Downloads 24 Institutions

All Articles in Small or Companion Animal Medicine

Faceted Search

1,272 full-text articles. Page 1 of 22.

Determination Of Ownership Practices And Cytauxzoon Felis Prevalence In Domestic Felines Of Northwest Arkansas, Daniella M. Duran 2021 University of Arkansas, Fayetteville

Determination Of Ownership Practices And Cytauxzoon Felis Prevalence In Domestic Felines Of Northwest Arkansas, Daniella M. Duran

Animal Science Undergraduate Honors Theses

Cytauxzoon felis is a protozoan pathogen that causes the infectious disease, cytauxzoonosis in wild and domestic felines. The natural host of this pathogen is the bobcat (Lynx rufus), which is why this disease is also commonly referred to as “bobcat fever”. The C. felis pathogen infects wild and domestic cats upon transmission by infected ticks. Amblyomma americanum, also known as the Lone Star tick, the primary transmission vector for C. felis. This tick species is largely populated throughout the state of Arkansas, making C. felis a large threat to wild and domestic felines in these areas. Cytauxzoonosis is commonly thought ...


Use Of Ultrasounds And Cystotomies In Diagnosing And Resolving Bladder Stones, Kirsten Cline 2021 Ursinus College

Use Of Ultrasounds And Cystotomies In Diagnosing And Resolving Bladder Stones, Kirsten Cline

Biology Presentations

The use of ultrasounds are the most safe and effective way to detect bladder stones. Bladder stones are easy to detect with acoustic shadowing, a white bright twinkle effect, and heaviness. Cystotomies are one of the most common procedures to solve bladder stones with one of the lowest mortality and morbidity rates. Kiara, a one year old feline presented with UTI symptoms and was diagnosed with bladder stones. An ultrasound was used and a cystotomy was performed.


Letter To The Editor Regarding “Efficacy Of Adding Ramipril (Vasotop) To The Combination Of Furosemide (Lasix) And Pimobendan (Vetmedin) In Dogs With Mitral Valve Degeneration: The Valve Trial”, Clarke Atkins, Bruce Keene, Teresa C. DeFrancesco, Sandra Tou, Valérie Chetboul, Étienne Côté, Stephen Ettinger, Philip R. Fox, Robert L. Hamlin, Jonathan P. Mochel, Jean‐Louis Pouchelon, Rebecca L. Stepien 2021 North Carolina State University

Letter To The Editor Regarding “Efficacy Of Adding Ramipril (Vasotop) To The Combination Of Furosemide (Lasix) And Pimobendan (Vetmedin) In Dogs With Mitral Valve Degeneration: The Valve Trial”, Clarke Atkins, Bruce Keene, Teresa C. Defrancesco, Sandra Tou, Valérie Chetboul, Étienne Côté, Stephen Ettinger, Philip R. Fox, Robert L. Hamlin, Jonathan P. Mochel, Jean‐Louis Pouchelon, Rebecca L. Stepien

Biomedical Sciences Publications

The manuscript entitled Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial1 reports a study which sought to answer the question “could pimobendan be all that is needed beyond loop diuretics to manage congestive heart failure (CHF) in myxomatous mitral valve disease (MMVD)?” This was done by prospectively comparing the efficacy of pimobendan + ramipril + furosemide (triple treatment) to pimobendan + furosemide (double treatment) to treat new‐onset CHF caused by MMVD.


Altered Corneal Innervation And Ocular Surface Homeostasis In Fhv-1-Exposed Cats: A Preliminary Study Suggesting Metaherpetic Disease, Lionel Sebbag, Sara M. Thomasy, Adriana Leland, Madison Mukai, Soohyun Kim, David J. Maggs 2021 Hebrew University of Jerusalem, University of California-Davis, and Iowa State University

Altered Corneal Innervation And Ocular Surface Homeostasis In Fhv-1-Exposed Cats: A Preliminary Study Suggesting Metaherpetic Disease, Lionel Sebbag, Sara M. Thomasy, Adriana Leland, Madison Mukai, Soohyun Kim, David J. Maggs

Veterinary Clinical Sciences Publications

Metaherpetic disease is recognized in humans affected by herpes simplex virus-1 but is not reported in cats affected by feline herpesvirus-1 (FHV-1) despite the high prevalence of herpetic disease in this species and strong similarities in viral biology between alphaherpesviruses of humans and cats. This preliminary work evaluated cats naïve to FHV-1 (n = 9 cats, 18 eyes; control population) and cats naturally exposed to FHV-1 (n = 4 cats, 7 eyes), as confirmed by serologic testing and review of medical records. Antemortem assessment included clinical scoring, blink rate, corneal aesthesiometry, tear film breakup time (TFBUT), and Schirmer tear test-1 (STT-1) with ...


Utility Of Point‐Of‐Care Lung Ultrasound For Monitoring Cardiogenic Pulmonary Edema In Dogs, Shane D. Murphy, Jessica L. Ward, Austin K. Viall, Melissa A. Tropf, Rebecca A. Walton, Jennifer L. Fowler, Wendy A. Ware, Teresa C. DeFrancesco 2020 Iowa State University

Utility Of Point‐Of‐Care Lung Ultrasound For Monitoring Cardiogenic Pulmonary Edema In Dogs, Shane D. Murphy, Jessica L. Ward, Austin K. Viall, Melissa A. Tropf, Rebecca A. Walton, Jennifer L. Fowler, Wendy A. Ware, Teresa C. Defrancesco

Veterinary Clinical Sciences Publications

Background Point‐of‐care lung ultrasound (LUS) is an effective tool to diagnose left‐sided congestive heart failure (L‐CHF) in dogs via detection of ultrasound artifacts (B‐lines) caused by increased lung water.

Hypothesis/Objectives To determine whether LUS can be used to monitor resolution of cardiogenic pulmonary edema in dogs, and to compare LUS to other indicators of L‐CHF control.

Animals Twenty‐five client‐owned dogs hospitalized for treatment of first‐onset L‐CHF.

Methods Protocolized LUS, thoracic radiographs (TXR), and plasma N‐terminal pro‐B‐type natriuretic peptide were performed at hospital admission, hospital discharge, and ...


Retrospective Evaluation Of The Safety And Tolerability Of Pimobendan In Cats With Obstructive Vs Nonobstructive Cardiomyopathy, Jessica Ward, Efrem Z. Kussin, Melissa A. Tropf, Sandra P. Tou, Teresa C. DeFrancesco, Bruce W. Keene 2020 Iowa State University

Retrospective Evaluation Of The Safety And Tolerability Of Pimobendan In Cats With Obstructive Vs Nonobstructive Cardiomyopathy, Jessica Ward, Efrem Z. Kussin, Melissa A. Tropf, Sandra P. Tou, Teresa C. Defrancesco, Bruce W. Keene

Veterinary Clinical Sciences Publications

Background Pimobendan is frequently used off‐label for treatments of cats with congestive heart failure (CHF). Concern exists regarding the safety of pimobendan in cats with outflow tract obstruction (OTO).

Objectives In cats treated with pimobendan, incidence of adverse effects will not differ between cats with OTO vs cats with nonobstructive cardiomyopathy.

Animals Two‐hundred sixty cats with CHF (57 with OTO, 203 with nonobstructive disease).

Methods Retrospective medical record review. Groups were compared using 2‐sample t‐tests, Wilcoxon rank‐sum tests, and Fisher exact tests.

Results Compared to cats with nonobstructive cardiomyopathy, cats with OTO were younger (8 ...


Afoxolaner As A Treatment For A Novel Sarcoptes Scabiei Infestation In A Juvenile Potbelly Pig, Joe S. Smith, Darren J. Berger, Sarah E. Hoff, Jeba R. J. Jesudoss Chelladurai, Katy A. Martin, Matthew T. Brewer 2020 Iowa State University

Afoxolaner As A Treatment For A Novel Sarcoptes Scabiei Infestation In A Juvenile Potbelly Pig, Joe S. Smith, Darren J. Berger, Sarah E. Hoff, Jeba R. J. Jesudoss Chelladurai, Katy A. Martin, Matthew T. Brewer

Veterinary Pathology Publications and Papers

A 2 months old female Vietnamese potbellied pig presented to a veterinary teaching hospital with a referring complaint of pruritus. A human caretaker of the pig had recently been diagnosed with a Sarcoptes spp. dermatitis. Microscopic examination of the skin scrape samples and BLAST analysis confirmed the species of the mite as most closely related to Sarcoptes scabiei var. canis (AY493391). The pig was treated with afoxolaner as previous treatment with ivermectin was not efficacious. Recheck examinations and follow up revealed the pig to be non-pruritic and resolving. Afoxolaner may be a therapeutic option when treating Sarcoptes spp. infections in ...


Laboratory Assays Reveal Diverse Phenotypes Among Microfilariae Of Dirofilaria Immitis Isolates With Known Macrocyclic Lactone Susceptibility Status, Jeba R.J. Jesudoss Chelladurai, Katy A. Martin, Krystal Chinchilla-Vargas, Pablo D. Jimenez Castro, Ray M. Kaplan, Matthew T. Brewer 2020 Iowa State University

Laboratory Assays Reveal Diverse Phenotypes Among Microfilariae Of Dirofilaria Immitis Isolates With Known Macrocyclic Lactone Susceptibility Status, Jeba R.J. Jesudoss Chelladurai, Katy A. Martin, Krystal Chinchilla-Vargas, Pablo D. Jimenez Castro, Ray M. Kaplan, Matthew T. Brewer

Veterinary Pathology Publications and Papers

Prevention of canine heartworm disease caused by Dirofilaria immitis relies on chemoprophylaxis with macrocyclic lactone anthelmintics. Alarmingly, there are increased reports of D. immitis isolates with resistance to macrocyclic lactones and the ability to break through prophylaxis. Yet, there is not a well-established laboratory assay that can utilize biochemical phenotypes of microfilariae to predict drug resistance status. In this study we evaluated laboratory assays measuring cell permeability, metabolism, and P-glycoprotein-mediated efflux. Our assays revealed that trypan blue, propidium iodide staining, and resazurin metabolism could detect differences among D. immitis isolates but none of these approaches could accurately predict drug susceptibility ...


Vitamin D Status In Cats With Cardiomyopathy, Wendy A. Ware, Lisa M. Freeman, John E. Rush, Jessica L. Ward, Andrew J. Makowski, Min Zhang 2020 Iowa State University

Vitamin D Status In Cats With Cardiomyopathy, Wendy A. Ware, Lisa M. Freeman, John E. Rush, Jessica L. Ward, Andrew J. Makowski, Min Zhang

Veterinary Clinical Sciences Publications

Background Low vitamin D concentrations have been associated with advanced heart disease and poorer outcomes in people and dogs. Vitamin D status typically is assessed by serum 25(OH)D concentration. However, cats also produce notable amounts of a C‐3 epimer of 25(OH)D (3‐epi).

Hypothesis/Objectives Determine if vitamin D status, estimated by 25(OH)D3 alone or combined with 3‐epi (summation vitD), is lower in cats with cardiomyopathy (CM) compared to clinically normal (N) cats and if indicators of disease severity are associated with vitamin D status.

Animals Privately owned cats, 44 with CM ...


Considerations In The Extrapolation Drug Toxicity Between Humans And Dogs, Marilyn N. Martinez, Jonathan P. Mochel, Devendra Pade 2020 United States Food and Drug Administration

Considerations In The Extrapolation Drug Toxicity Between Humans And Dogs, Marilyn N. Martinez, Jonathan P. Mochel, Devendra Pade

Biomedical Sciences Publications

The dog is an important species used in preclinical studies in support of human drug product development. Likewise, because of the many active pharmaceutical ingredients (APIs) with therapeutic relevance to both humans and dogs, extrapolation can also occur in the reverse, from human to dog. In either situation, it is important to appreciate species-specific factors influencing drug pharmacokinetics (absorption, metabolism, disposition, and elimination) and the potential impact of disease on the applicability of these extrapolations. Furthermore, tools such as physiologically based pharmacokinetic (PBPK) models not only enable investigators to extrapolate species-specific data on systemic or organ exposure to the parent ...


Whole Genome Sequencing For Mutation Discovery In A Single Case Of Lysosomal Storage Disease (Mps Type 1) In The Dog, Tamer A. Mansour, Kevin D. Woolard, Karen L. Vernau, Devin M. Ancona, Sara M. Thomasy, Lionel Sebbag, Bret A. Moore, Marguerite F. Knipe, Haitham A. Seada, Tina M. Cowan, Miriam Aguilar, C. Titus Brown, Danika L. Bannasch 2020 University of California, Davis and Mansoura University

Whole Genome Sequencing For Mutation Discovery In A Single Case Of Lysosomal Storage Disease (Mps Type 1) In The Dog, Tamer A. Mansour, Kevin D. Woolard, Karen L. Vernau, Devin M. Ancona, Sara M. Thomasy, Lionel Sebbag, Bret A. Moore, Marguerite F. Knipe, Haitham A. Seada, Tina M. Cowan, Miriam Aguilar, C. Titus Brown, Danika L. Bannasch

Veterinary Clinical Sciences Publications

Mucopolysaccharidosis (MPS) is a metabolic storage disorder caused by the deficiency of any lysosomal enzyme required for the breakdown of glycosaminoglycans. A 15-month-old Boston Terrier presented with clinical signs consistent with lysosomal storage disease including corneal opacities, multifocal central nervous system disease and progressively worsening clinical course. Diagnosis was confirmed at necropsy based on histopathologic evaluation of multiple organs demonstrating accumulation of mucopolysaccharides. Whole genome sequencing was used to uncover a frame-shift insertion affecting the alpha-L-iduronidase (IDUA) gene (c.19_20insCGGCCCCC), a mutation confirmed in another Boston Terrier presented 2 years later with a similar clinical picture. Both dogs were homozygous ...


Spontaneous Pneumothorax In A Companion Kunekune Pig Due To Pulmonary Bullae Rupture, Joe Smith, Matthew Cuneo, Rebecca A. Walton, Robin White, Roselle Busch, Munashe Chigerwe 2020 Iowa State University

Spontaneous Pneumothorax In A Companion Kunekune Pig Due To Pulmonary Bullae Rupture, Joe Smith, Matthew Cuneo, Rebecca A. Walton, Robin White, Roselle Busch, Munashe Chigerwe

Veterinary Diagnostic and Production Animal Medicine Publications

Background Pneumothorax cases are commonly described in mammals, but descriptions in Kunekune pigs are lacking.

Case description A three-month-old, male Kunekune pig (Sus scrofa domesticus) presented for respiratory distress of 24 hours duration. Based on physical examination, blood gas analysis, ultrasound, and radiography, a presumed diagnosis of pneumothorax secondary to a ruptured pulmonary bullae was made. The presence of pulmonary bullae was confirmed via computed tomography. The pneumothorax was managed with indwelling thoracostomy tubes, constant suction, nasal oxygen supplementation, antimicrobials and anti-inflammatories. Subsequent bloodwork, cytology, parasitology, and culture results discounted an infectious or inflammatory etiology. The patient was discharged ten ...


Development And Management Of Canine Adverse Food Reactions And Its Connections To The Grain-Free Dog Food Movement, Savannah Dunn 2020 Liberty University

Development And Management Of Canine Adverse Food Reactions And Its Connections To The Grain-Free Dog Food Movement, Savannah Dunn

Senior Honors Theses

Canine Adverse Food Reactions include immunologically-mediated food allergies as well as non-immunological food intolerances. Although popular belief holds grains are responsible for AFR, the majority are aggravated by the common protein sources found in commercial dog foods. Elimination diets, a time-intensive method in which suspected allergens are removed from the dog’s diet, are the most effective form of diagnosis, though alternative techniques including patch testing and serum antibody tests have been explored. Presently, avoidance of allergens is the recommended management approach. The erroneous association of grains with AFR has led to the rise of grain-free dog food. However, these ...


The Parasite Giardia, Ashley Anderson 2020 University of Nebraska - Lincoln

The Parasite Giardia, Ashley Anderson

Honors Theses, University of Nebraska-Lincoln

The focus of this research is to better understand how this parasite works. The protozoan Giardia spp is found all over the world and in many species such as dogs, cats, and humans. From its two different forms to the microscopic size of both forms to its ability to destroy intestinal villi and cause symptoms like other parasitic infections, Giardia spp is continuously misdiagnosed. Upon further observation at veterinary clinics and researching science articles, Giardia spp is most commonly found in pets but has the potential to spread to humans via contaminated water. The most commonly infected humans are hikers ...


Aqueous Tear Assessment In Dogs: Impact Of Cephalic Conformation, Inter‐Test Correlations, And Test‐Retest Repeatability, Hellen Bolzani, Arianne P. Oriá, Ana Claudia S. Raposo, Lionel Sebbag 2020 Federal University of Bahia

Aqueous Tear Assessment In Dogs: Impact Of Cephalic Conformation, Inter‐Test Correlations, And Test‐Retest Repeatability, Hellen Bolzani, Arianne P. Oriá, Ana Claudia S. Raposo, Lionel Sebbag

Veterinary Clinical Sciences Publications

Objective - To characterize diagnostic findings, test‐retest repeatability, and correlations among lacrimal tests in dogs of diverse cephalic conformations.

Animal studied - Fifty healthy dogs (25 brachycephalic, 25 nonbrachycephalic).

Procedures - A series of diagnostics were performed in each dog, allowing for a 10‐minute interval between tests and repeating each test 24 hours later under similar conditions: corneal tactile sensation (CTS), strip meniscometry test (SMT), phenol red thread test (PRTT), endodontic absorbent paper point tear test (EAPPTT), Schirmer tear test‐1 without (STT‐1) or with nasolacrimal stimulation (NL‐STT1), and Schirmer tear test‐2 (STT‐2).

Results - Mean ± SD test ...


The Effect Of Intravenous Maropitant On Blood Pressure In Healthy Awake And Anesthetized Dogs, Ting-Ting Chi, Bonnie L. Hay Kraus 2020 Iowa State University

The Effect Of Intravenous Maropitant On Blood Pressure In Healthy Awake And Anesthetized Dogs, Ting-Ting Chi, Bonnie L. Hay Kraus

Veterinary Clinical Sciences Publications

Objective To evaluate the effects of intravenous maropitant on arterial blood pressure in healthy dogs while awake and under general anesthesia.

Design Experimental crossover study.

Animals Eight healthy adult Beagle dogs.

Procedure All dogs received maropitant (1 mg kg-1) intravenously under the following conditions: 1) awake with non-invasive blood pressure monitoring (AwNIBP), 2) awake with invasive blood pressure monitoring (AwIBP), 3) premedication with acepromazine (0.005 mg kg-1) and butorphanol (0.2 mg kg-1) intramuscularly followed by propofol induction and isoflurane anesthesia (GaAB), and 4) premedication with dexmedetomidine (0.005 mg kg-1) and butorphanol (0.2 mg kg-1) intramuscularly followed ...


Apparent Total Tract Digestibility, Fecal Characteristics, And Blood Parameters Of Healthy Adult Dogs Fed High Fat Diets, Logan R. Kilburn, Karin Allenspach, Albert E. Jergens, Agnes Bourgois-Mochel, Jonathan P. Mochel, Mariana C. Rossoni Serao 2020 Iowa State University

Apparent Total Tract Digestibility, Fecal Characteristics, And Blood Parameters Of Healthy Adult Dogs Fed High Fat Diets, Logan R. Kilburn, Karin Allenspach, Albert E. Jergens, Agnes Bourgois-Mochel, Jonathan P. Mochel, Mariana C. Rossoni Serao

Biomedical Sciences Publications

Pet foods may be formulated with decreased starch to meet consumer demands for less processed diets. Fats and oils may be added to low starch diets to meet energy requirements, but little is known about its effects on canine health. The study objective was to evaluate the effects of feeding healthy adult dogs low carbohydrate, high-fat diets on apparent total tract digestibility, fecal characteristics, and overall health status. Eight adult beagles were enrolled in a replicated 4x4 Latin Square design feeding trial. Dogs were randomly assigned to 1 of 4 dietary fat level treatments (T) within each period: 32% (T1 ...


Albumin Levels In Tear Film Modulate The Bioavailability Of Medically-Relevant Topical Drugs, Lionel Sebbag, Leah M. Moody, Jonathan P. Mochel 2020 Iowa State University

Albumin Levels In Tear Film Modulate The Bioavailability Of Medically-Relevant Topical Drugs, Lionel Sebbag, Leah M. Moody, Jonathan P. Mochel

Veterinary Clinical Sciences Publications

The breakdown of blood-tear barrier that occurs with ocular pathology allows for large amounts of albumin to leak into the tear fluid. This process likely represents an important restriction to drug absorption in ophthalmology, as only the unbound drug is transported across the ocular tissue barriers to exert its pharmacologic effect. We aimed to investigate the effects of albumin levels in tears on the bioavailability of two commonly used ophthalmic drugs: tropicamide, an antimuscarinic that produces mydriasis and cycloplegia, and latanoprost, a PGF2α analog used for the treatment of glaucoma. Eight female beagle dogs underwent a randomized, vehicle-controlled crossover trial ...


A Case Of A Linear Foreign Body Removal In A Miniature Companion Pig, Alison Cain, Jordan Kirkpatrick, Ryan Breuer, Robin White, Joe Smith 2020 Iowa State University

A Case Of A Linear Foreign Body Removal In A Miniature Companion Pig, Alison Cain, Jordan Kirkpatrick, Ryan Breuer, Robin White, Joe Smith

Veterinary Diagnostic and Production Animal Medicine Publications

Despite the recent rise in popularity of miniature pigs as companion animals, there are few published reports available regarding gastrointestinal surgery in these animals. This case report describes a 4-year-old castrated male companion potbellied pig who was diagnosed with a small bowel linear foreign body and associated pyloric outflow obstruction. A gastrotomy and three enterotomies involving the proximal and mid-jejunum and proximal centripetal loop of the spiral colon were performed to remove the linear foreign body. The surgical techniques and post-operative care described in this case report provided effective treatment of the linear foreign body and adequately prevented clinical evidence ...


Evaluación Biomecánica Ex Vivo De Cuatro Métodos De Estabilización Para El Avance De La Tuberosidad Tibial En Caninos, Mayra Alejandra Fajardo Zabala 2020 Universidad de La Salle, Bogotá

Evaluación Biomecánica Ex Vivo De Cuatro Métodos De Estabilización Para El Avance De La Tuberosidad Tibial En Caninos, Mayra Alejandra Fajardo Zabala

Maestría en Ciencias Veterinarias

La ruptura del ligamento cruzado craneal (RLCC), es descrita como la causa más común de claudicación en caninos. Las técnicas quirúrgicas descritas para la estabilización de la articulación incluyen: estabilización intraarticular o extraarticular y técnicas modificadoras de la biomecánica, dentro de estas últimas se encuentra el avance de la tuberosidad tibial (TTA). La técnica quirúrgica de TTA fue descrita en el 2002, y busca modificar el ángulo entre el plato tibial y el tendón patelar y llevarlo a 90°, en dicho ángulo se inhibe el empuje tibial y por tanto se logra la estabilización dinámica de la articulación de la ...


Digital Commons powered by bepress