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Small or Companion Animal Medicine Commons

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Ex Vivo Biomechanical Comparison Of Four Center Of Rotation Angulation Based Leveling Osteotomy Fixation Methods, Melody E. Whitney 2022 Mississippi State University

Ex Vivo Biomechanical Comparison Of Four Center Of Rotation Angulation Based Leveling Osteotomy Fixation Methods, Melody E. Whitney

Theses and Dissertations

Thirty-two canine tibiae with patellae and patellar tendons were harvested from 17 skeletally mature cadavers. Each tibia was randomly allocated to a construct group: plate and pin (Plate), plate with countersink compression screw (HCS), plate with tension band (TB), or plate with HCS and TB (HCSTB). Samples were loaded by distraction until failure. The stiffness, yield load, and ultimate load were compared between each fixation method. No difference in stiffness of the constructs was detected between groups. Yield load and ultimate load for the HCSTB group was greater than the TB group, the HCS group, and the Plate group. CBLO …


Comparison Of Water-Soluble Cbd And Cbd Oil As An Anti-Inflammatory In Canines With Osteoarthritis, Sadie Sims, Sadie Sims, Tara Joiner, Dr. Laura Ken Hoffman, Barbie Papajeski 2022 Murray State University

Comparison Of Water-Soluble Cbd And Cbd Oil As An Anti-Inflammatory In Canines With Osteoarthritis, Sadie Sims, Sadie Sims, Tara Joiner, Dr. Laura Ken Hoffman, Barbie Papajeski

Honors College Theses

Osteoarthritis is one of the most common forms of arthritis in canines. Osteoarthritis affects the entire joint, and typically results in pain, inflammation, decreased range of motion and development of bone spurs. The purpose of this study was to provide clinical research comparing Water-Soluble Cannabidiol (CBD) and Cannabidiol (CBD) oil as an anti-inflammatory in arthritic dogs by using gait analysis on the Tekscan Strideway System, Canine Brief Pain Inventory owner surveys, and analysis of blood test results. One clinical trial was conducted with thirteen privately owned dogs. Participants were split into three treatment groups by listing them by last names …


Ex Vivo Biomechanical Evaluation Of A Novel Screw For Tibial Plateau Leveling Osteotomy, William Seth Kettleman 2022 Mississippi State University

Ex Vivo Biomechanical Evaluation Of A Novel Screw For Tibial Plateau Leveling Osteotomy, William Seth Kettleman

Theses and Dissertations

Twelve pairs of cadaveric pelvic limbs were harvested from skeletally mature dogs. Tibias were randomly assigned pairwise to two study groups: locking buttress screw fixation (LBS) and bone-screw-fastener fixation (BSF). A tibial plateau leveling osteotomy (TPLO) was performed. Each specimen was positioned in a servohydraulic testing machine to simulate physiological orientation and loading at the mid-point of the stance phase at the walk. Cyclic loading was performed for 30,000 cycles at 4Hz with a peak-load of 1000N. The cyclic test was then continued by stepwise increasing the peak-load at a rate of 75N per 500 cycles until failure of the …


Impact Of Fatty Acid On Markers Of Exocrine Pancreatic Stimulation, Yunyi Zhang 2022 University of Tennessee, Knoxville

Impact Of Fatty Acid On Markers Of Exocrine Pancreatic Stimulation, Yunyi Zhang

Masters Theses

Chronic pancreatitis in dogs is typically managed with a low-fat diet. Human research suggests consuming medium-chain triglycerides (MCT) may lower pancreatic enzyme release compared to consuming long chain fatty acids (LCFA). Twelve healthy adult colony dogs were fed a meal of cod and rice with either 3% metabolizable energy (ME) fat (control), high MCT (25% ME MCT oil, 25% ME butter), high saturated LCFA (50% ME butter), or high unsaturated LCFA (50% ME canola oil) in a 4-period by 4-treatment crossover design. Serum concentrations of canine pancreatic lipase immunoreactivity, gastrin, amylase, cholecystokinin (CCK), cholesterol, triglycerides and serum activities of DGGR …


Comparison Of Abdominal Computed Tomography To Ultrasound In The Diagnosis Of Canine Biliary Disease Manifesting As Acute Abdominal Signs, Shanna Christine Marroquin 2022 Mississippi State University

Comparison Of Abdominal Computed Tomography To Ultrasound In The Diagnosis Of Canine Biliary Disease Manifesting As Acute Abdominal Signs, Shanna Christine Marroquin

Theses and Dissertations

Biliary diseases are uncommon, potentially fatal causes of acute abdomen in dogs. Little information is present comparing the performance of computed tomography (CT) to ultrasound in identifying canine biliary pathology. Thirty-five client-owned dogs presenting for acute abdomen signs received an abdominal ultrasound and contrast-enhanced abdominal CT. Two authors reviewed the randomized, anonymized CT and ultrasound studies. Twenty-eight dogs had biliary pathology and seven dogs serving as controls had no evidence of biliary disease. The final diagnoses of patients with biliary pathology included cholelithiasis, gallbladder mucoceles, cholangiohepatitis/cholangitis, extrahepatic biliary obstruction, gallbladder wall edema, gallbladder wall mass, and cystic mucosal hyperplasia. Computed …


Characterization Of The Fecal Microbiome In Dogs Receiving Medical Management For Congenital Portosystemic Shunts, Nathan Squire 2022 University of Tennessee College of Comparative and Experimental Medicine

Characterization Of The Fecal Microbiome In Dogs Receiving Medical Management For Congenital Portosystemic Shunts, Nathan Squire

Masters Theses

Background: The GI microbiome has not been characterized in dogs being medically managed for congenital portosystemic shunts [CPSS].

Objectives: To characterize the fecal microbiome in a population of dogs being medically managed for CPSS.

Animals: 27 client-owned dogs.

Methods: Prospective cohort study enrollment of fecal samples was performed with follow-up data collected retrospectively. The overall fecal dysbiosis index [DI] and individual bacterial abundances were determined using real-time qPCR. Medical management, clinical findings, clinicopathologic, and outcome variables were collected, and logistic regression analyses were performed to evaluate associations between these variables and overall DI and bacterial abundances. Numerical variables were evaluated …


Barriers To Client Compliance And Understanding Of Heartworm Prevention In The Canine Patient, Emily Fischels 2022 Murray State University

Barriers To Client Compliance And Understanding Of Heartworm Prevention In The Canine Patient, Emily Fischels

Honors College Theses

Dirofilaria immitis is a common and largely preventable mosquito-borne parasite that causes dirofilariasis, or heartworm disease, in a number of animal species. The necessity of heartworm prevention in the canine patient is undisputed and well-known among veterinary professionals, yet there are still many dogs not protected from this fatal parasite. Heartworm prevention traditionally requires a once-a-month administration of medication; therefore, its efficacy relies on owner compliance. The barriers to canines receiving heartworm prevention were assessed using a survey targeted at pet owners whose dogs have seen the veterinarian in the past year. The main barriers identified were inadequate client communication …


Polydactyly In Cats, Rosa Benson, Cassie Morris, Leaha Mancuso, Bernardo Mesa 2022 Harrisburg University of Science and Technology

Polydactyly In Cats, Rosa Benson, Cassie Morris, Leaha Mancuso, Bernardo Mesa

Harrisburg University Research Symposium

Polydactyly is a genetic condition in which a cat is born with more than the typical number of toes. It is a dominant genetic mutation and is fairly common in cats. (Class Project)


A Novel Endo Gia™ Staple Cartridge For Canine Lung Lobectomies, Alissa St. Blanc 2022 Louisiana State University and Agricultural and Mechanical College

A Novel Endo Gia™ Staple Cartridge For Canine Lung Lobectomies, Alissa St. Blanc

LSU Master's Theses

The canine lungs are well suited for ventilation, gas exchange, and gas transport. In diseased states, changes within bronchi and pulmonary parenchyma alter the blood-gas interface. Diagnostic workups to characterize pulmonary disease may include blood gas analysis, bronchoalveolar lavage, tracheobronchoscopy, radiography and/or computed tomography. Surgical pulmonary diseases include cysts, bullae, and blebs; congenital anomalies; consolidation or abscessation; bronchiectasis; lacerations; lung lobe torsions; and neoplasia. Surgical options may include laceration repair, partial or total lung lobectomy, and pneumonectomy. These options are most commonly utilized in cases that fail medical management. Lung lobectomies were originally performed using suture ligation. Stapling devices have …


Accuracy Of A Sacral Drilling With A Custom 3d Printed Drilling Guide Or Free-Hand Technique In Canine Experimental Sacroiliac Luxation, Daniel McCarthy 2022 Louisiana State University

Accuracy Of A Sacral Drilling With A Custom 3d Printed Drilling Guide Or Free-Hand Technique In Canine Experimental Sacroiliac Luxation, Daniel Mccarthy

LSU Master's Theses

ABSTRACT

The objective of this study was to improve the accuracy of drilling during the repair of sacroiliac luxation with a 3D-printed patient-specific drill guide (3D-GDT) compared to free-hand drilling technique (FHDT). A blinded, randomized, prospective study was performed including sixteen canine cadavers (20-25 kg) euthanized for reasons not related to the study. Dorsal, bilateral, sacroiliac luxations (SILs) were created experimentally. A pelvic CT was performed pre- and post-drilling. The FHDT was drilled followed by 3D-GDT for each sacrum. CT and 3D measurements of craniocaudal and dorsoventral angles were compared between FHDT and 3D-GDT, as well as deviations of entry …


Pets And Problems: Exploring Community Patterns In Calls For Animal Services, Paige DeJarnett 2021 University of Arkansas, Fayetteville

Pets And Problems: Exploring Community Patterns In Calls For Animal Services, Paige Dejarnett

Sociology and Criminology Undergraduate Honors Theses

Pets have historically been viewed as family members, children, property, or economic resources. However, research surrounding animal maltreatment has expressed this issue as an individually-based problem, rather than a community-based phenomenon. Correlations have been found between animal cruelty, antisocial behaviors, and future interpersonal violence, whether this correlation be a predictive relationship, or a resultant relationship. Past research has also found correlations between animal treatment practices and the rural/urban differences of this behavior. However, there are many community-based indicators that have not been explored to understand the distribution of animal maltreatment. This study aims to explore these ideas by analyzing the …


Investigation Of Semiquantitative Marrow Iron Scoring And Reticulocyte Hemoglobin Content (Chr) In Healthy And Ill Canines With And Without Clinical Evidence Of Blood Loss., Grace A. Pawsat 2021 University of Tennessee, Knoxville

Investigation Of Semiquantitative Marrow Iron Scoring And Reticulocyte Hemoglobin Content (Chr) In Healthy And Ill Canines With And Without Clinical Evidence Of Blood Loss., Grace A. Pawsat

Masters Theses

Background: Insufficient iron for erythropoiesis can occur in multiple conditions, including absolute iron deficiency, which is often caused by chronic external hemorrhage in dogs. Distinguishing this from other causes of iron-restricted erythropoiesis allows appropriate intervention. Decreased marrow iron assessed by Prussian blue staining is considered the gold standard to diagnose absolute iron deficiency but scoring systems are not validated in dogs. The performance of standardized semiquantitative marrow scoring of iron deposits in dogs has not been previously reported or correlated to iron biomarkers in blood.[1-4]

Objectives: Objectives included evaluation of the effects of different staining sequences, evaluation the technical performance …


Investigating Media Influence On Canine Breed Popularity And Increasing Prevalence Of Genetic Linked Disorders, Callie Anderson 2021 Murray State University

Investigating Media Influence On Canine Breed Popularity And Increasing Prevalence Of Genetic Linked Disorders, Callie Anderson

Honors College Theses

This study is focused on influence of social media on dog breed popularity, and if an increase in popularity leads to an increase in the prevalence of genetic-linked disorders observed in specified breeds in a clinical setting. This study was conducted by comparing an in-depth analysis of past research investigating the influence of popular culture on the trends of dog breed popularity as it relates to trends in media and fashion, with the results of a survey of clinical observations by veterinarians practicing in the area surrounding Murray, Kentucky. The results of the literary analysis revealed that humans are greatly …


Determination Of Ownership Practices And Cytauxzoon Felis Prevalence In Domestic Felines Of Northwest Arkansas, Daniella M. Duran 2021 University of Arkansas, Fayetteville

Determination Of Ownership Practices And Cytauxzoon Felis Prevalence In Domestic Felines Of Northwest Arkansas, Daniella M. Duran

Animal Science Undergraduate Honors Theses

Cytauxzoon felis is a protozoan pathogen that causes the infectious disease, cytauxzoonosis in wild and domestic felines. The natural host of this pathogen is the bobcat (Lynx rufus), which is why this disease is also commonly referred to as “bobcat fever”. The C. felis pathogen infects wild and domestic cats upon transmission by infected ticks. Amblyomma americanum, also known as the Lone Star tick, the primary transmission vector for C. felis. This tick species is largely populated throughout the state of Arkansas, making C. felis a large threat to wild and domestic felines in these areas. Cytauxzoonosis is commonly thought …


Compounded Gabapentin For Felines: Associated Metabolic Processes And Analysis Of Potency, Johnny Altwal 2021 Chapman University

Compounded Gabapentin For Felines: Associated Metabolic Processes And Analysis Of Potency, Johnny Altwal

Student Scholar Symposium Abstracts and Posters

Pharmaceutical compounding provides pharmacists and clinicians the opportunity to create unique drug formulations that are better suited to a specific patient’s needs. This is especially prevalent in veterinary medicine where clinicians treat a variety of maladies in a large number of species, thereby requiring unique formulations to more easily deliver drugs to animals. Several examples of compounded veterinary formulations with sub-therapeutic potencies have been published, but none examine compounded gabapentin. Gabapentin is frequently compounded into an oral suspension for veterinary use from tablets or capsules for the purpose of pain management in felines and other small animals. The project’s goals …


Use Of Ultrasounds And Cystotomies In Diagnosing And Resolving Bladder Stones, Kirsten Cline 2021 Ursinus College

Use Of Ultrasounds And Cystotomies In Diagnosing And Resolving Bladder Stones, Kirsten Cline

Biology Presentations

The use of ultrasounds are the most safe and effective way to detect bladder stones. Bladder stones are easy to detect with acoustic shadowing, a white bright twinkle effect, and heaviness. Cystotomies are one of the most common procedures to solve bladder stones with one of the lowest mortality and morbidity rates. Kiara, a one year old feline presented with UTI symptoms and was diagnosed with bladder stones. An ultrasound was used and a cystotomy was performed.


Differentiation Of The Can F 1 Allergen In Hypoallergenic Dog Saliva Compared To Shedding Dog Saliva, Rose Miller 2021 Murray State University

Differentiation Of The Can F 1 Allergen In Hypoallergenic Dog Saliva Compared To Shedding Dog Saliva, Rose Miller

Honors College Theses

Dog saliva contains a large variety of proteins, each with specific functions throughout the body. While some aid in digestion, others provide immune support for the body. In the case of human dog allergies, dog skin dander has been proven to cause allergic reactions to those who are sensitive to the allergens in the dogs. However, past studies have shown a difference in allergic reaction to specific breeds, breaking dog breeds into two main categories: hypoallergenic and non-hypoallergenic. Within these groups, there are different hypoallergenicity levels, but overall, the hypoallergenic dog group does not cause an allergic reaction, whereas non-hypoallergenic, …


Anesthetic Combination Of Alfaxalone, Dexmedetomidine And Hydromorphone For Comparison Of Endoscopy-Guided Intubation And Blind Orotracheal Intubation In Domestic Rabbits (Oryctolagus Cuniculus), Stephanie Reabel 2021 Louisiana State University and Agricultural and Mechanical College

Anesthetic Combination Of Alfaxalone, Dexmedetomidine And Hydromorphone For Comparison Of Endoscopy-Guided Intubation And Blind Orotracheal Intubation In Domestic Rabbits (Oryctolagus Cuniculus), Stephanie Reabel

LSU Master's Theses

Domestic rabbits have a high risk of anesthesia-related mortality compared to other companion animals. Factors that may contribute to increased mortality include drug-induced cardiopulmonary effects (Grint & Murison 2008; Navarrete-Calvo et al. 2013), difficulty performing intubation (Aeschbacher 1995; Flecknell 2016; Wenger et al. 2017) or damage to laryngeal and tracheal tissues following orotracheal intubation (Grint et al. 2006; Phaneuf et al. 2006; Engbers et al. 2017).

Alfaxalone is a neuroactive steroid that produces induction of anesthesia and cardiorespiratory depression in a dose-dependent manner when injected intravenously. The ability to induce anesthesia via an intramuscular (IM) route has several advantages in …


Characterization Of Memory T-Lymphocyte Subsets In Dogs, Annie Beth Bauman 2021 Louisiana State University and Agricultural and Mechanical College

Characterization Of Memory T-Lymphocyte Subsets In Dogs, Annie Beth Bauman

LSU Master's Theses

A more complete understanding of canine T-cell immunity is necessary for improving diagnostic and therapeutic approaches to canine diseases, developing cell-based canine immunotherapeutics, and evaluating dogs as large mammal models for comparative immunology research. Canine immunological studies are limited by the lack of established phenotypic markers identifying diverse differentiation states in canine T-cells. Differential expression of CD45RA (indicating antigen experience) and CD62L (indicating lymph node homing capability), shows promise as a tool to delineate canine naïve (TN), central memory (TCM), effector memory (TEM), and terminal effector memory (TEMRA) T-cells. The aim of this study was to characterize canine memory T-cell …


Dirofilaria Immitis Prevalence In Canis Latrans In Kentucky, Melanie Ann Brandon 2021 Murray State University

Dirofilaria Immitis Prevalence In Canis Latrans In Kentucky, Melanie Ann Brandon

Murray State Theses and Dissertations

Dirofilaria immitis (canine heartworm) was found in forty-two (42) of the two hundred seventy-five (275) Canis latrans (coyote) necropsied in the state of Kentucky from November 27, 2019 through March 3, 2021. Thirty-five (35) of the positive cases were from western Kentucky region with the other seven spread across the state. With this group of coyotes, one hundred fifty-eight (158) were male and the other one hundred six-teen (116) were female. The estimated age ranged from a pup to senior dogs. A little over forty percent of the dogs were obtained through coyote/predator tournaments; the remaining were acquired from pest …


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