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Prevalence And Characteristics Of Feline Pleural Effusion In Khon Kaen, Thailand: A 2024–2025 Study, Karn Yongvanit, Naruepon Kampa 2026 Faculty of Veterinary Medicine, Khon Kaen University

Prevalence And Characteristics Of Feline Pleural Effusion In Khon Kaen, Thailand: A 2024–2025 Study, Karn Yongvanit, Naruepon Kampa

The Thai Journal of Veterinary Medicine

Pleural effusion (PE) is a life-threatening condition in cats that can cause severe respiratory compromise. Identification of the underlying etiology is essential for prognosis and treatment planning. This study investigated the prevalence and characteristics of diseases associated with feline pleural effusion in northeastern Thailand. Medical records of cats diagnosed with pleural effusion at the Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Khon Kaen University, Thailand, between January 2024 and January 2025 were retrospectively reviewed. Cases lacking a complete diagnostic workup were excluded. Diagnoses were confirmed using cytology or histopathology for neoplasia, echocardiography for heart disease, polymerase chain reaction (PCR) for …


Distribution Of Urinary Calculi And Its Association With Clinical And Laboratory Findings In Dogs And Cats With Stone Analysis At Chulalongkorn Animal Teaching Hospital, Thailand (2020-2024), Tanattha Ladabornvidhaya, Natkrita Baikloy, Theaparak Thipjaroen, Parapond Kongrakchang, Warisara Kaechaiya, Sumonwan Chamsuwan, Monkon Trisiriroj, Chollada Buranakarl 2026 Faculty of Veterinary Science, Chulalongkorn University

Distribution Of Urinary Calculi And Its Association With Clinical And Laboratory Findings In Dogs And Cats With Stone Analysis At Chulalongkorn Animal Teaching Hospital, Thailand (2020-2024), Tanattha Ladabornvidhaya, Natkrita Baikloy, Theaparak Thipjaroen, Parapond Kongrakchang, Warisara Kaechaiya, Sumonwan Chamsuwan, Monkon Trisiriroj, Chollada Buranakarl

The Thai Journal of Veterinary Medicine

Urinary calculi are commonly encountered in veterinary practice; however, information regarding their distribution of stone that underwent analysis and associated clinical findings remains limited. This study investigated the distribution of urolithiasis and the associations between stone types and clinical and laboratory findings in dogs and cats presented to the Chulalongkorn Small Animal Teaching Hospital between 2020 and 2024. The three most common stone types in both species were calcium oxalate (CaOx), struvite, and urate, with relatively stable trends over the 5-year period. Small-breed dogs had a higher risk of developing CaOx urolithiasis than medium-breed dogs (OR = 10.4, 95% CI …


Minimally Invasive Percutaneous Endoscopic Foraminotomy And Discectomy In A French Bulldog With Intervertebral Disc Extrusion, Tanhatai Krajarngjang, Luksamee Limpongsai, Panutda Darapong, Woraphanit Sonbanpai, Mataya Taweechart 2026 Arak Animal Hospital

Minimally Invasive Percutaneous Endoscopic Foraminotomy And Discectomy In A French Bulldog With Intervertebral Disc Extrusion, Tanhatai Krajarngjang, Luksamee Limpongsai, Panutda Darapong, Woraphanit Sonbanpai, Mataya Taweechart

The Thai Journal of Veterinary Medicine

A six-year-old female French Bulldog was referred for neurological diagnostic tests and treatment for progressive paraparesis over an 8-day period. The dog had a history of intervertebral disc extrusion (IVDE) surgical correction two years prior. Neurological examination revealed T3–L3 myelopathy. Magnetic resonance imaging of the thoracolumbar spine confirmed IVDE with spinal cord compression at T13–L1. A minimally invasive percutaneous endoscopic foraminotomy and discectomy (PEFD) was performed to remove the extruded disc material. The patient regained the ability to stand and showed voluntary limb movement 48 hours post-surgery. At the 4-week follow-up, the patient showed a complete recovery to her baseline …


Transfemoral Approach To Patent Ductus Arteriosus Occlusion Using Acdo In A Dog With Complex Surgical History, Nawat Sannamwong, Hataichon Owatdhumma, Kornrawee Tharavanij, Thitinan Tangarsasilp, Nardtiwa Chaivoravitsakul, Kongthit Horoongruang, Patmanachatr Bunnag, Nakkawee Saengklub, Krishaporn Kradangnga, Sirilak Disatian Surachetpong, Anusak Kijtawornrat 2026 Faculty of Veterinary Science, Chulalongkorn University

Transfemoral Approach To Patent Ductus Arteriosus Occlusion Using Acdo In A Dog With Complex Surgical History, Nawat Sannamwong, Hataichon Owatdhumma, Kornrawee Tharavanij, Thitinan Tangarsasilp, Nardtiwa Chaivoravitsakul, Kongthit Horoongruang, Patmanachatr Bunnag, Nakkawee Saengklub, Krishaporn Kradangnga, Sirilak Disatian Surachetpong, Anusak Kijtawornrat

The Thai Journal of Veterinary Medicine

A five-year-old spayed female Welsh Corgi weighing 12.4 kg presented with exercise intolerance and was diagnosed with a patent ductus arteriosus (PDA). Due to signs of left-sided volume overload, the dog was initially managed with oral pimobendan and was subsequently referred to the Small Animal Teaching Hospital at Chulalongkorn University for further evaluation and intervention. Upon presentation, the patient was bright, alert, and responsive, with a body condition score of 6 out of 9 and normal muscle condition. The mucous membranes were pink and moist, with a capillary refill time of 1 to 2 seconds. A continuous heart murmur was …


Choledochoduodenostomy For The Treatment Of Extrahepatic Bile Duct Carcinoma In A Cat, Qi Zhang, Chunli Han, Anchi Zhang, Zhiying Wan, Yansong Ge, Zheng Wang, Jiasan Zheng 2026 College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University

Choledochoduodenostomy For The Treatment Of Extrahepatic Bile Duct Carcinoma In A Cat, Qi Zhang, Chunli Han, Anchi Zhang, Zhiying Wan, Yansong Ge, Zheng Wang, Jiasan Zheng

The Thai Journal of Veterinary Medicine

This paper reports a case of feline cholangiocarcinoma, a relatively rare condition in veterinary clinical practice. A 4-year-old female British Shorthair cat was presented with a 10-day history of anorexia and lethargy. An irregularly shaped mass was palpable on abdominal palpation. Diagnostic imaging and serum biochemical findings indicated extrahepatic biliary obstruction, and the diagnosis of cholangiocarcinoma was confirmed by histopathology and immunohistochemistry. Preoperative imaging in this cat indicated that the mass had not invaded major blood vessels such as the portal vein, and no evidence of distant metastasis was detected. The mass was surgically resected, followed by choledochoduodenostomy. The cat …


Serial Radiographic And Ultrasonographic Evaluation Of Discospondylitis In A Cat: A Case Report Of Progressive Vertebral Lysis Despite Clinical Improvement, Geunah Kim, Jungho Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee 2026 College of Veterinary Medicine, Kyungpook National University

Serial Radiographic And Ultrasonographic Evaluation Of Discospondylitis In A Cat: A Case Report Of Progressive Vertebral Lysis Despite Clinical Improvement, Geunah Kim, Jungho Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

A 10-year-old castrated male Korean Shorthair cat was presented with a 5-day history of lethargy and nonambulatory paraparesis. Neurological examination revealed delayed postural reactions in both pelvic limbs. Initial radiography of the lumbar spine revealed narrowing of the L7–S1 intervertebral disc space with ventral bony proliferation. Magnetic resonance imaging revealed collapse of the L7–S1 intervertebral disc space with heterogeneous T2-weighted hyperintensity and ventral contrast enhancement of the affected disc, as well as contrast enhancement of the adjacent paraspinal musculature. These findings suggested the presence of discospondylitis. Coccoid bacteria detected in both urine and splenic fine-needle aspirate indicated hematogenous spread. The …


Hypovitaminosis A - Associated Neurologic Syndrome With Concurrent Babesiosis In A Captive African Lion Cub (Panthera Leo), Kano, Nigeria, Shaarani Habibu Musa, Aminu Bello Hanga, Auwal Usman Nagoma, Caleb Ayuba Kudi, Paul Ayuba Abdu, Musa Ibrahim Waziri, Haruna Baba Galadima, Yusuf Aminu Yusuf, Muhammed Mikail 2026 Ministry for Livestock Development, Kano State

Hypovitaminosis A - Associated Neurologic Syndrome With Concurrent Babesiosis In A Captive African Lion Cub (Panthera Leo), Kano, Nigeria, Shaarani Habibu Musa, Aminu Bello Hanga, Auwal Usman Nagoma, Caleb Ayuba Kudi, Paul Ayuba Abdu, Musa Ibrahim Waziri, Haruna Baba Galadima, Yusuf Aminu Yusuf, Muhammed Mikail

The Thai Journal of Veterinary Medicine

Neurological disorders in captive wild felids presents diagnostic and therapeutic challenges, particularly in juveniles animals maintained under suboptimal nutritional transitions. This case report describes the synergistic effects of dietary deficiencies and a concurrent hemoparasitic infection in a seven-month-old male African lion cub (Panthera leo) weighing 30 kg, housed at Audu Bako Zoological Garden in Kano, Nigeria. Following premature weaning onto an unsupplemented muscle-meat diet, the cub exhibited progressive neurological symptoms, including ataxia, hindlimb paresis, star-gazing, and opisthotonos. Hematological analysis revealed a mild normocytic, normochromic anemia (packed cell volume; 23%) and the presence of erythrocytes rouleaux formation, while Giemsa-stained …


Comparative Hematological And Biochemical Alterations Associated With Gram-Negative Bacterial Infections Of Lower Urinary Tract In Dogs And Cats, Mohamed Alasmar, Maged El-Ashker, Mohammed Albaloushi, Mayyadah Alkuwayti, Mohamed Marzok 2026 Faculty of Veterinary Medicine, Mansoura University

Comparative Hematological And Biochemical Alterations Associated With Gram-Negative Bacterial Infections Of Lower Urinary Tract In Dogs And Cats, Mohamed Alasmar, Maged El-Ashker, Mohammed Albaloushi, Mayyadah Alkuwayti, Mohamed Marzok

The Thai Journal of Veterinary Medicine

The aim of this study was to investigate hematological and biochemical alterations associated with gram-negative bacterial lower urinary tract infections (UTIs) in dogs and cats. For this purpose, 56 dogs and 36 cats were examined between October 2022 and May 2023. Twenty-eight dogs and twenty-two cats with clinical signs of lower UTIs were confirmed using ultrasonography, urinalysis, hematobiochemical analysis, and molecular identification of recovered pathogen. In dogs, UTIs were significantly associated with pyuria (82%), crystalluria (85.7%), and proteinuria. There was also significant decrease in total protein and globulin levels compared to those in the control. A significant increase in BUN, …


A Study Of Descriptive Values Of Echocardiography In Unanesthetized Syrian Hamsters, Kasidit Ladkhoksung, Nattapart Lerdkarnvijai, Thanakorn Ngamsawat, Napassorn Napassorn, Suphisara Chantharadech, Pattharat Asvaesoontorn, Thawat Lekdumrongsak, Sirilak Surachetpong 2026 Faculty of Veterinary Science, Chulalongkorn University

A Study Of Descriptive Values Of Echocardiography In Unanesthetized Syrian Hamsters, Kasidit Ladkhoksung, Nattapart Lerdkarnvijai, Thanakorn Ngamsawat, Napassorn Napassorn, Suphisara Chantharadech, Pattharat Asvaesoontorn, Thawat Lekdumrongsak, Sirilak Surachetpong

The Thai Journal of Veterinary Medicine

The Syrian hamster (Mesocricetus auratus) is the most commonly presented hamster species in veterinary practice, yet descriptive echocardiographic values remain limited, particularly under conscious conditions. This study aimed to establish normal two-dimensional, M-mode, and Doppler echocardiographic values in healthy conscious Syrian hamsters and to evaluate the influence of age, body weight, and sex on cardiac parameters. Forty Syrian hamsters (27 males and 12 females; one excluded) underwent physical examination, thoracic radiography, and echocardiography. Age and body weight were recorded. Echocardiographic parameters were analyzed for their distribution and correlation with age and body weight. All echocardiographic parameters demonstrated a …


Assessment Of Platelet Activation In Dogs With Naturally Occurring Acute Pancreatitis, Guhyun Kwon, Seulgi Bae 2026 College of Veterinary Medicine, Kyungpook National University

Assessment Of Platelet Activation In Dogs With Naturally Occurring Acute Pancreatitis, Guhyun Kwon, Seulgi Bae

The Thai Journal of Veterinary Medicine

Recent studies have demonstrated that platelets are crucial in inflammation and immune responses. Alteration in platelet activity impact morbidity and survival due to the formation of intravascular clots or bleeding resulting from impaired platelet function. Aiming to evaluate changes in platelet activity in dogs with naturally occurring acute pancreatitis (AP), we identified differences in quantitative and morphological platelet indices, as well as the ratio of platelets expressing P-selectin on their surface (activated platelet ratio; APR) between dogs with naturally occurring AP and healthy dogs. The study included 9 client-owned dogs with AP (the AP group) and 28 client-owned healthy dogs …


Ultrasound-Guided Percutaneous Sclerotherapy Of A Canine Hepatic Cyst Using Lower-Concentration Ethanol: A Case Report, Minyoung Kim, Dongyeong Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee 2026 College of Veterinary Medicine, Kyungpook National University

Ultrasound-Guided Percutaneous Sclerotherapy Of A Canine Hepatic Cyst Using Lower-Concentration Ethanol: A Case Report, Minyoung Kim, Dongyeong Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

A 10-year-old female Pomeranian was referred after a hepatic cyst was incidentally identified during a routine health check. Ultrasound-guided simple drainage was initially performed, and cytological examination of the aspirated fluid confirmed a simple cyst. However, the cyst re-expanded to its original size within 2 weeks. Therefore, ultrasound-guided percutaneous sclerotherapy was elected using lower-concentration ethanol (83%), a readily available medical disinfectant, rather than conventional high-concentration ethanol. Approximately 50% of the aspirated volume was replaced with 83% ethanol and retained for 20 min to achieve effective epithelial ablation. Post-procedural follow-up revealed a transient increase in cyst size and serum alanine aminotransferase …


Ultrasonography Accompanied By Genetic Testing In Feline Polycystic Kidney Disease, Thao Phuong Vu, Thong Quang Le, Ha Nguyen Nhat Tran, Khoa Hoang Dang Le, Anh Phu Nam Bui 2026 Ho Chi Minh City Open University

Ultrasonography Accompanied By Genetic Testing In Feline Polycystic Kidney Disease, Thao Phuong Vu, Thong Quang Le, Ha Nguyen Nhat Tran, Khoa Hoang Dang Le, Anh Phu Nam Bui

The Thai Journal of Veterinary Medicine

Autosomal dominant polycystic kidney disease (ADPKD), caused by the PKD1 c.10063C>A mutation, is a prevalent inherited feline disorder, but its allele frequency in Vietnam remains unidentified. This study aimed to determine the carrier frequency of this variant in British Shorthair, Maine Coon, and Ragdoll cats in Ho Chi Minh City and to correlate genotype with ultrasonographic phenotype. Ninety-seven client-owned cats were genotyped for the pkd1 mutation using PCR-RFLP. A subset of 47 cats also underwent abdominal ultrasonography to detect renal cysts. Genotypic results were correlated with sonographic findings, and risk factors were analyzed using chi-square tests and odds ratios …


Epidemiologic Evaluation Of Canine Urate Urolithiasis In Thailand: A Comparative Cross-Sectional Study Between 2016-2023, Nattaporn Chaysakul, Jody P. Lulich, Vachira Hunprasit 2026 Faculty of Veterinary Medicine, Chulalongkorn University

Epidemiologic Evaluation Of Canine Urate Urolithiasis In Thailand: A Comparative Cross-Sectional Study Between 2016-2023, Nattaporn Chaysakul, Jody P. Lulich, Vachira Hunprasit

The Thai Journal of Veterinary Medicine

A comparative cross-sectional study aimed to describe the epidemiological data of canine urate urolithiasis in Thailand by evaluating the change in proportion over the year and identifying risk-associated factors, including age, breed, sex, and neutered status, through comparisons with multiple comparison groups. The urate and non-urate group was dogs whose uroliths were submitted from Thailand to the Minnesota Urolith Center between 2016 and 2023, and the hospital group was dogs that were visited at the Small Animal Hospital, Chulalongkorn University, between 2020 and 2023. Of 6,171 canine urolith submissions, 210 samples (3.4%) were urate-containing uroliths submitted from twenty-eight canine breeds. …


Evaluation Of Bone Turnover Markers And Biochemical Analysis In Developmental Metabolic Bone Diseases In Pediatric Aksaray Malakli Breed Dogs, Nihan Avci, Fehmiye Gumus Ozdil, Basak Boztok Ozgermen 2026 Faculty of Veterinary Medicine, Aksaray University

Evaluation Of Bone Turnover Markers And Biochemical Analysis In Developmental Metabolic Bone Diseases In Pediatric Aksaray Malakli Breed Dogs, Nihan Avci, Fehmiye Gumus Ozdil, Basak Boztok Ozgermen

The Thai Journal of Veterinary Medicine

Pediatric dogs are predisposed to skeletal disorders during growth, with rickets, hypertrophic osteopathy, and nutritional secondary hyperparathyroidism being the most common. Rickets, usually caused by vitamin D deficiency, leads to bone softening and deformities, whereas hypertrophic osteopathy involves abnormal calcium salt deposition that impairs mobility. This study investigated developmental orthopedic diseases in Aksaray Malakli dogs, focusing on nutritional factors and biochemical markers. Twenty-two pediatric dogs were examined and divided into two groups. Group I (n=11) showed gait abnormalities and postural deformities, whereas Group II (n=11) included clinically healthy dogs. Clinical, radiographic, and biochemical assessments were performed, including cortical index, parathormone, …


Microrna Expression In Putative Cancer Stem Cells Isolated From Canine Mammary Gland Tumour Cells With Differing Sensitivity To Doxorubicin, Kabiru Sahabi, Gayathri Thevi Selvarajah, Mohd Mokrish Md Ajat, Rasedee Abdullah, Cheah Y. Kqueen 2026 Faculty of Veterinary Medicine, Universiti Putra Malaysia; Faculty of Veterinary Medicine, Universiti Malaysia Kelantan

Microrna Expression In Putative Cancer Stem Cells Isolated From Canine Mammary Gland Tumour Cells With Differing Sensitivity To Doxorubicin, Kabiru Sahabi, Gayathri Thevi Selvarajah, Mohd Mokrish Md Ajat, Rasedee Abdullah, Cheah Y. Kqueen

The Thai Journal of Veterinary Medicine

Cancer stem cells (CSCs) are capable of initiating tumour development and causing recurrence after treatment. The objective of this study was to determine the miRNAs, downstream target mRNAs, and signalling pathways in CSCs isolated from doxorubicin-sensitive and doxorubicin-resistant canine mammary adenocarcinoma cell lines. MicroRNA expression was profiled using Agilent SurePrint® microarrays. MicroRNA data were analyzed using Agilent GeneSpring® software, and TargetScan and WikiPathways were used to identify genes and pathways targeted by the differentially expressed miRNAs. Six miRNAs were differentially expressed in CSCs isolated from doxorubicinsensitive cells, while fourteen miRNAs were differentially expressed in CSCs isolated from doxorubicin-resistant …


Possible Intervertebral Disc Disease Related To Ventricular Tachycardia In A Labrador Retriever, Nadthagarn Glaewketgarn, Sirilak Disatian Surachetpong 2026 Faculty of Veterinary Science, Chulalongkorn University

Possible Intervertebral Disc Disease Related To Ventricular Tachycardia In A Labrador Retriever, Nadthagarn Glaewketgarn, Sirilak Disatian Surachetpong

The Thai Journal of Veterinary Medicine

Ventricular arrhythmia (VA) is a common arrhythmia in dogs. Several extracardiac causes such as pain may contribute this condition. This case report describes a 9-year-old neutered male Labrador Retriever with ventricular tachycardia (VT) potentially related to severe neck pain due to intervertebral disc disease (IVDD). The dog was referred with a sign of inability to walk, tachypnea and an irregular heartbeat. Electrocardiography confirmed VT at 160-200 bpm and an increased cardiac troponin I level (35.22 ng/ml). Despite antiarrhythmic treatment, the VT persisted. Cardiac evaluation revealed no structural abnormalities. Interestingly, VT episodes were provoked by cervical palpation and resolved following analgesic …


Feasibility Of Computed Tomography For Differentiating Calcium Oxalate And Struvite Calculi Using Mean Hounsfield Unit And Hounsfield Density, Somchin Sutthigran, Phasamon Saisawart, Vachira Hunprasit, Nan Choisunirachon, Kiatpichet Komin 2025 Faculty of Veterinary Medicine, Mahanakorn University of Technology

Feasibility Of Computed Tomography For Differentiating Calcium Oxalate And Struvite Calculi Using Mean Hounsfield Unit And Hounsfield Density, Somchin Sutthigran, Phasamon Saisawart, Vachira Hunprasit, Nan Choisunirachon, Kiatpichet Komin

The Thai Journal of Veterinary Medicine

Accurate preoperative prediction of cystic calculi composition is essential for effective treatment planning in dogs. This prospective study aims to investigate the utility of non-contrast multi-detector computed tomography (MDCT) in differentiating calcium oxalate (CaOx) and struvite calculi based on mean Hounsfield unit (HU) and HU density values. Nineteen client-owned dogs with confirmed cystic calculi underwent non-contrast MDCT imaging at 80 and 120 kilovoltage peak (kVp) settings prior to surgical removal. Calculi composition was determined via laboratory analysis. Mean HU and HU density were measured and compared between calculi types. The results showed CaOx calculi demonstrated significantly higher mean HU (1317.53 …


Combination Of Prednisolone And Mycophenolate Mofetil For The Treatment Of A Cat With Immune-Mediated Panniculitis: A Case Report, J.H. Kim, M.H. Jeon, Y.S. Kwon, Seulgi Bae 2025 College of Veterinary Medicine, Kyungpook National University

Combination Of Prednisolone And Mycophenolate Mofetil For The Treatment Of A Cat With Immune-Mediated Panniculitis: A Case Report, J.H. Kim, M.H. Jeon, Y.S. Kwon, Seulgi Bae

The Thai Journal of Veterinary Medicine

A 3-year-old domestic shorthair cat presented with severe diffuse skin lacerations and cutaneous nodules with purulent discharge. Primary immune-mediated panniculitis was diagnosed. After surgical excision of the lesions, immunosuppressive therapy with prednisolone and mycophenolate mofetil was initiated. The cutaneous lesions resolved, and no recurrence was observed over a 2-year follow-up period.


Feline Conjunctivitis In Sleman Region Indonesia: Clinical Characteristics, Bacteriological Isolation Of Staphylococcus Aureus, And Antimicrobial Susceptibility, Agung Budi Pramono, Fatkhanudin Aziz, Faiz Ihsanul Kamil, Soedarmanto Indarjulianto, Ida Tjahajati 2025 Faculty of Veterinay Medicine, Universitas Gadjah Mada

Feline Conjunctivitis In Sleman Region Indonesia: Clinical Characteristics, Bacteriological Isolation Of Staphylococcus Aureus, And Antimicrobial Susceptibility, Agung Budi Pramono, Fatkhanudin Aziz, Faiz Ihsanul Kamil, Soedarmanto Indarjulianto, Ida Tjahajati

The Thai Journal of Veterinary Medicine

Conjunctivitis is a common ocular condition in domestic cats, often associated with Staphylococcus aureus. Accurate detection and resistance profiling are essential for appropriate therapy. This study aimed to characterize clinical features of feline conjunctivitis, identify S. aureus using phenotypic and genotypic methods, and assess its antibiotic susceptibility. Twenty conjunctivitis-suspected cats in Sleman, Indonesia, underwent clinical examination and conjunctival swabbing. Bacterial isolates were cultured on Mannitol Salt Agar and identified by Gram stain, catalase, coagulase, biochemical tests, and PCR targeting 23S rRNA. Susceptibility to gentamicin, chloramphenicol, ciprofloxacin, and amoxicillin was tested by Kirby-Bauer. Predominant signs included excessive tearing (95%), hyperemia …


Rapid Post-Castration Decline In Serum Canine Prostatic Specific Esterase (Cpse) And Prostatic Volume In Dogs With Benign Prostatic Hyperplasia, Panthipa Borikappakul, Junpen Suwimonteerabutr, Suppawiwat Ponglowhapan 2025 Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University

Rapid Post-Castration Decline In Serum Canine Prostatic Specific Esterase (Cpse) And Prostatic Volume In Dogs With Benign Prostatic Hyperplasia, Panthipa Borikappakul, Junpen Suwimonteerabutr, Suppawiwat Ponglowhapan

The Thai Journal of Veterinary Medicine

The objectives of this study were to quantify temporal changes in prostatic volume and serum CPSE concentrations in dogs with benign prostatic hyperplasia (BPH) (n = 6) following surgical castration, and to evaluate the potential of CPSE as a biomarker for monitoring prostatic regression. Prostatic volume was determined by transabdominal ultrasonography, and serum CPSE concentrations were measured at baseline (Week 0) and at Weeks 1, 2, and 4 postcastration. The mean (±SE) prostatic volume before castration was 11.4 ± 1.9 cm3 and decreased significantly to 6.3±1.1 cm3 by Week 1 (P < 0.001), representing a reduction to approximately 56% of the baseline value. Smaller progressive declines were observed at subsequent time points up to Week 4 (P > 0.05). In parallel, serum CPSE concentrations dropped …


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