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Accelerated Aging: A Marker For Social Factors Resulting In Cardiovascular Events?, Sarah N. Forrester, Rachel Zmora, Pamela J. Schreiner, David R. Jacobs Jr., Veronique L. Roger, Roland J. Thorpe Jr., Catarina I. Kiefe 2021 University of Massachusetts Medical School

Accelerated Aging: A Marker For Social Factors Resulting In Cardiovascular Events?, Sarah N. Forrester, Rachel Zmora, Pamela J. Schreiner, David R. Jacobs Jr., Veronique L. Roger, Roland J. Thorpe Jr., Catarina I. Kiefe

Population and Quantitative Health Sciences Publications

Background: Medicine and public health are shifting away from a purely "personal responsibility" model of cardiovascular disease (CVD) prevention towards a societal view targeting social and environmental conditions and how these result in disease. Given the strong association between social conditions and CVD outcomes, we hypothesize that accelerated aging, measuring earlier health decline associated with chronological aging through a combination of biomarkers, may be a marker for the association between social conditions and CVD.

Methods: We used data from the Coronary Artery Risk Development in Young Adults study (CARDIA). Accelerated aging was defined as the difference between biological and chronological ...


The Intestinal And Oral Microbiomes Are Robust Predictors Of Covid-19 Severity The Main Predictor Of Covid-19-Related Fatality [Preprint], Doyle V. Ward, Shakti Bhattarai, Mayra Rojas-Correa, Ayan Purkayastha, Devon Holler, Ming Da Qu, William G. Mitchell, Jason D. Yang, Samuel Fountain, Abigail Zeamer, Catherine Forconi, Gavin Fujimori, Boaz Odwar, Caitlin Cawley, Beth A. McCormick, Ann M. Moormann, Mireya Wessolossky, Vanni Bucci, Ana Maldonado-Contreras 2021 University of Massachusetts Medical School

The Intestinal And Oral Microbiomes Are Robust Predictors Of Covid-19 Severity The Main Predictor Of Covid-19-Related Fatality [Preprint], Doyle V. Ward, Shakti Bhattarai, Mayra Rojas-Correa, Ayan Purkayastha, Devon Holler, Ming Da Qu, William G. Mitchell, Jason D. Yang, Samuel Fountain, Abigail Zeamer, Catherine Forconi, Gavin Fujimori, Boaz Odwar, Caitlin Cawley, Beth A. Mccormick, Ann M. Moormann, Mireya Wessolossky, Vanni Bucci, Ana Maldonado-Contreras

University of Massachusetts Medical School Faculty Publications

The reason for the striking differences in clinical outcomes of SARS-CoV-2 infected patients is still poorly understood. While most recover, a subset of people become critically ill and succumb to the disease. Thus, identification of biomarkers that can predict the clinical outcomes of COVID-19 disease is key to help prioritize patients needing urgent treatment. Given that an unbalanced gut microbiome is a reflection of poor health, we aim to identify indicator species that could predict COVID-19 disease clinical outcomes. Here, for the first time and with the largest COVID-19 patient cohort reported for microbiome studies, we demonstrated that the intestinal ...


Learning Innovation And Service-Learning In Medical Apparel Development Of Entrepreneurship: Face-Covering, Changhyun (Lyon) Nam, Srikant Manchiraju, Eulanda A. Sanders 2021 Florida State University

Learning Innovation And Service-Learning In Medical Apparel Development Of Entrepreneurship: Face-Covering, Changhyun (Lyon) Nam, Srikant Manchiraju, Eulanda A. Sanders

Apparel, Events and Hospitality Management Conference Proceedings and Presentations

The Medical Apparel Development of Entrepreneurship course helps students: (a) understand fundamental product development concept and the process, (b) implement medical apparel development of entrepreneurship incorporating 3D printing, and (c) contribute to local community service centers for a service-learning practice task. The overall design concept and process will be useful in course content, including seven face-covering steps during the sixteenweek course. It is imperative for academia and industry to collaborate and contribute to finding an optimal face-covering prototype, created from suitable materials and elastics, which is washable, reusable, and hygienic better to understand the unique and straightforward pattern and design ...


Covid-10, Healthcare Interior Design + Provider Experience - How Does Your Space Work For You?, Ruth E.P. Deibler 2021 Virginia Commonwealth University

Covid-10, Healthcare Interior Design + Provider Experience - How Does Your Space Work For You?, Ruth E.P. Deibler

Graduate Research Posters

The lack of research on healthcare staff experience and interior design of the spaces they work in is evident. A focus on staff perspective is needed, particularly staff who navigated the COVID-19 pandemic. This research seeks to capture those stories to develop further research in order to improve staff experience. The initial phase of this mixed-methods approach is a survey. Hypothetically, by placing providers at the center of qualitative research related to healthcare interior design, we can better understand existing healthcare spaces. Ideally, we can develop additional evidence-based, human-centered solutions to transform interior environments in healthcare.

The 20-year Women’s ...


Evaluating Patient And Provider Knowledge Of Safe Pharmaceutical Disposal Procedures In Vermont Through A Public Health And Environmental Lens, Emily R. Straley 2021 Larner College of Medicine at the University of Vermont

Evaluating Patient And Provider Knowledge Of Safe Pharmaceutical Disposal Procedures In Vermont Through A Public Health And Environmental Lens, Emily R. Straley

Family Medicine Clerkship Student Projects

Patient and provider knowledge of safe pharmaceutical disposal procedures is crucial from both a public health and environmental standpoint. Unfortunately, studies have shown that Vermont residents are largely unaware of safe drug disposal programs in their communities. This project evaluated patient knowledge of drug disposal practices and awareness of safe pharmaceutical disposal procedures at Hinesburg Family Medicine. A short phrase was created to better disseminate information about safe drug disposal in Hinesburg, which can be added to a patient’s after visit summary. Many patients report never discussing medication disposal with their physician. Therefore, increased provider communication regarding leftover and ...


Impact Of Covid-19 On Ohio's National Parks Visitation, Ryan Grzeschik 2021 The University of Akron

Impact Of Covid-19 On Ohio's National Parks Visitation, Ryan Grzeschik

Williams Honors College, Honors Research Projects

The COVID-19 pandemic has fundamentally changed the way in which society operates in order to get the novel disease under control. Businesses throughout the United States have had to close or reduce provided services, stay at home orders have secluded many people, and social distancing limits contact between others so many are turning to the parks system to cope with these changes. This study aims to find how the visitation of national parks in Ohio have been affected through the first six months of the pandemic. Visitation statistics were compared from March to August of 2020 to those same months ...


History Of Deer Herd Reduction For Tick Control On Maine’S Offshore Islands, Susan P. Elias, Benjamin B. Stone, Peter W. Rand, Charles B. Lubelczyk, Robert P. Smith MD 2021 Maine Medical Center Research Institute

History Of Deer Herd Reduction For Tick Control On Maine’S Offshore Islands, Susan P. Elias, Benjamin B. Stone, Peter W. Rand, Charles B. Lubelczyk, Robert P. Smith Md

Maine Policy Review

The incidence of Lyme disease in Maine is associated with high abundance of blacklegged (deer) ticks, which in turn has been partly attributed to local overabundance of white-tailed deer. With evidence from Monhegan Island that the complete removal of deer reduced ticks and risk of contracting Lyme disease, nine other offshore communities initiated efforts to cull deer. We reviewed and summarized available histories of deer management on Maine’s offshore islands. Concern about Lyme disease provided the overarching impetus for deer culls. Culls mostly occurred on islands that have no regular firearms hunting season, island communities have been challenged to ...


Heat Stress In Urban Environments: A Case Study Of Heat Vulnerability In New Haven, Ct, Logan M. Howard 2021 Yale University

Heat Stress In Urban Environments: A Case Study Of Heat Vulnerability In New Haven, Ct, Logan M. Howard

Library Map Prize

A place-based understanding of heat and its behavior is necessary for appropriately preparing our cities and protecting the most vulnerable populations from this urgent climate and public health threat. This paper aims to identify the areas in New Haven, CT that have the highest autumnal temperature exposure and sensitivity to provide evidence for developing mitigation and adaptation measures. Original temperature data was collected using a bike-mounted Smart T sensor and then compared with data on land cover and water proximity. These heat exposure estimates were analyzed with 2019 Census data on age, income, race, and ethnicity, for 19 census tracts ...


An Assessment Of Contamination Fingerprinting Techniques For Determining The Impact Of Domestic Wastewater Treatment Systems On Private Well Supplies, Chris Fennell, Bruce Misstear, David O'Connell, Donata Dubber, Patrice Behan, Martin Danaher, Mary Moloney, Laurence Gill 2021 Trinity College Dublin, Ireland

An Assessment Of Contamination Fingerprinting Techniques For Determining The Impact Of Domestic Wastewater Treatment Systems On Private Well Supplies, Chris Fennell, Bruce Misstear, David O'Connell, Donata Dubber, Patrice Behan, Martin Danaher, Mary Moloney, Laurence Gill

Articles

Private wells in Ireland and elsewhere have been shown to be prone to microbial contamination with the main suspected sources being practices associated with agriculture and domestic wastewater treatment systems (DWWTS). While the microbial quality of private well water is commonly assessed using faecal indicator bacteria, such as Escherichia coli, such organisms are not usually source-specific, and hence cannot definitively conclude the exact origin of the contamination. This research assessed a range of different chemical contamination fingerprinting techniques (ionic ratios, artificial sweeteners, caffeine, fluorescent whitening compounds, faecal sterol profiles and pharmaceuticals) as to their use to apportion contamination of private ...


When Disparities Become Deadly: Spatial Differences In Pm2.5 Levels Within The City Of Pomona, California, Pauline Bekkers 2021 Claremont Colleges

When Disparities Become Deadly: Spatial Differences In Pm2.5 Levels Within The City Of Pomona, California, Pauline Bekkers

Pomona Senior Theses

This thesis discusses the disparities in particulate matter concentrations between different neighborhoods in the city of Pomona, California, and explores the historical, political and social factors that have shaped these spatial patterns. I argue that urban growth patterns in Pomona, which are historically marked by race and class segregation as a consequence of past discriminatory housing practices, have led to the disproportionate concentrations of air pollutants in low-income, Latino communities in South Pomona.

Due to the absence of a local air quality monitoring system, there is a lack of information about and understanding of how poor air quality may be ...


Organophosphate Pesticide Dose Estimation From Spot And 24-Hr Urine Samples Collected From Children In An Agricultural Community, Carly Hyland, Katherine Kogut, Robert B. Gunier, Rosemary Castorina, Cynthia Curl, Brenda Eskenazi, Asa Bradman 2021 University of California at Berkeley

Organophosphate Pesticide Dose Estimation From Spot And 24-Hr Urine Samples Collected From Children In An Agricultural Community, Carly Hyland, Katherine Kogut, Robert B. Gunier, Rosemary Castorina, Cynthia Curl, Brenda Eskenazi, Asa Bradman

Community and Environmental Health Faculty Publications and Presentations

Background: Spot urine samples are often used to assess exposure to organophosphate (OP) pesticides in place of “gold standard” 24-hr samples, which are cumbersome to collect. Assessment of non-persistent chemicals using spot urine samples may result in exposure misclassification that could bias epidemiological analyses towards the null. Few studies have examined the validity of measurements of urinary metabolites in spot samples to estimate daily OP dose or the potential implications of reliance on spot samples for risk assessments.

Objective: Examine the validity of using first morning void (FMV) and random non-FMV urine samples to estimate cumulative 24-hr OP pesticide dose ...


A Model For Inhalation Of Infectious Aerosol Contaminants In An Aircraft Passenger Cabin, Bert A. Silich 2021 Vector Vantage LLC

A Model For Inhalation Of Infectious Aerosol Contaminants In An Aircraft Passenger Cabin, Bert A. Silich

International Journal of Aviation, Aeronautics, and Aerospace

Aerosol contamination of an aircraft cabin by infectious passengers is a concern of passengers, aircrew and the aviation industry. This may be especially important during a pandemic, such as COVID-19, where the full extent of aerosol transmission is not well understood. A statistical method to determine the number of infectious passengers on board along with a mathematical model estimating the contaminant concentration of aerosols in the cabin and the number of inhaled infectious particles by passengers is presented. An example is used to demonstrated how the results can be estimated during normal operations and emergency conditions with malfunctions of the ...


Socioeconomic Status And Psychosocial Resources Mediate Racial/Ethnic Differences In Psychological Health Among Gay And Bisexual Men: A Longitudinal Analysis Using Structural Equation Modeling, Rainier Masa, Sylvia Shangani, Don Operario 2021 Old Dominion University

Socioeconomic Status And Psychosocial Resources Mediate Racial/Ethnic Differences In Psychological Health Among Gay And Bisexual Men: A Longitudinal Analysis Using Structural Equation Modeling, Rainier Masa, Sylvia Shangani, Don Operario

Community & Environmental Health Faculty Publications

A large body of research demonstrates disparities in psychological health attributed to sexual minority identity, racial/ethnic minority identity, and socioeconomic status (SES). Fewer studies have explicated the role of these multiple attributes on psychological health and explored the role of SES and psychosocial resources in determining outcomes. We analyzed data from Project STRIDE, a longitudinal survey involving a diverse sample of gay and bisexual adult men (n = 198). Using structural equation modeling, we tested hypothesized direct and indirect effects of race/ethnicity, SES, and three psychosocial mediational variables (collective self-efficacy, everyday discrimination, internalized homophobia) on two outcome variables-psychological and ...


Health Literacy Of University Students In Covid-19 Pandemic And Infodemic: A Pakistani Perspective, Rozeen Shaukat, Muhammad Asif Naveed 2021 Office of Research Innovation and Commercialization, University of Management and Technology, Lahore

Health Literacy Of University Students In Covid-19 Pandemic And Infodemic: A Pakistani Perspective, Rozeen Shaukat, Muhammad Asif Naveed

Library Philosophy and Practice (e-journal)

This research investigated the levels of health literacy among Pakistani university students in the Covid-19 pandemic and infodemic. The university students were surveyed using an online questionnaire at two public sector universities and one private sector university in Punjab-Pakistan. The administration of the data collection instrument was completed with permission from concerned authorities. A total of 374 responses received which were imported to SPSS and analyzed by applying descriptive as well as inferential statistics. The results revealed that the health literacy of university students in the Covid-19 pandemic and infodemic was not at an optimal level as these participants expressed ...


Tragedy Of The Energy Commons: How Government Regulation Can Help Mitigate The Environmental And Public Health Consequences Of Cryptocurrency Mining, Jeff Thomson 2020 Seattle University

Tragedy Of The Energy Commons: How Government Regulation Can Help Mitigate The Environmental And Public Health Consequences Of Cryptocurrency Mining, Jeff Thomson

Seattle Journal of Technology, Environmental & Innovation Law

The use of cryptocurrencies in daily life has continued to rise over the last decade and shows no signs of slowing down. Although cryptocurrencies, such as Bitcoin, provide numerous tangible benefits to society, the process of mining these cryptocurrencies is extremely energy intensive. Accordingly, a tragedy of the energy commons has resulted whereby the monetary incentive to mine cryptocurrencies has distorted our collective ability to care for our shared energy resources. The current system allows for industrious individuals to set up cryptocurrency mines in regions that have access to plentiful and cheap energy sources, utilize this energy to power their ...


Implementation And Program Evaluation Pilot Study: Educating Health Care Providers About Protecting Population Health During Climate Change., Christine Fasching Maphis 2020 James Madison University

Implementation And Program Evaluation Pilot Study: Educating Health Care Providers About Protecting Population Health During Climate Change., Christine Fasching Maphis

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Recommendations regarding the need to prepare nurses and other health care providers (HCPs) for the health impacts of climate change (CC) have grown ubiquitous in the literature. Timely, efficient and sustainable strategies by the health care industry are necessary. Failure to act is predicted to result in catastrophic and lethal population health consequences. A growing body of research identifies related knowledge gaps and supports HCP competencies and best practice interventions to mitigate adverse population health impacts of CC. A social ecological framework and the PRECEDE-PROCEED approach were employed to develop and evaluate a series of online webinars designed to equip ...


Mitigation Of Teratogenic Agents: Is There Promise In Ion Modulating Drugs?, Aastha Pokharel 2020 University of Massachusetts Amherst

Mitigation Of Teratogenic Agents: Is There Promise In Ion Modulating Drugs?, Aastha Pokharel

Masters Theses

As reported by the CDC, birth defects remain a common occurrence in the United States, with malformations originating in many places in the developing organism. Furthermore, the etiology of many of these defects remain unknown, with some factors consisting of genetics, environmental pollutants and teratogens. In our study, we examined whether insults by teratogenic agents, ethanol in particular, can be mitigated by hyperpolarizing agents acting to restore the cell’s potential. We first evaluated whether three hyperpolarizing drugs (Lamotrigine, Gabapentin, and Ivermectin) induced teratogenic effects on CD-1 mice and found that Ivermectin induced craniofacial malformations, and exposure to Lamotrigine and ...


Coal Energy And Environmental Impacts: Introduction, Luis F. O. Silva, Amy L. Wolfe 2020 Universidad de La Costa, Colombia

Coal Energy And Environmental Impacts: Introduction, Luis F. O. Silva, Amy L. Wolfe

Kentucky Geological Survey Faculty Publications

No abstract provided.


High School Students As Citizen Scientists To Decrease Radon Exposure, Ellen J. Hahn, Craig Wilmhoff, Mary Kay Rayens, Nicholas B. Conley, Emily Morris, Angela Larck, Trista Allen, Susan M. Pinney 2020 University of Kentucky

High School Students As Citizen Scientists To Decrease Radon Exposure, Ellen J. Hahn, Craig Wilmhoff, Mary Kay Rayens, Nicholas B. Conley, Emily Morris, Angela Larck, Trista Allen, Susan M. Pinney

Nursing Faculty Publications

Residents in rural Kentucky (KY) and suburban Ohio (OH) expressed concerns about radon exposure and lung cancer. Although 85% of lung cancer cases are caused by tobacco smoke, radon exposure accounts for 10–15% of lung cancer cases. Academic and community members from the University of KY and the University of Cincinnati developed and pilot-tested a family-centered, youth-engaged home radon testing toolkit. The radon toolkit included radon information, and how to test, interpret, and report back findings. We educated youth as citizen scientists and their teachers in human subjects protection and home radon testing using the toolkit in the classroom ...


Physicochemical Characterization And Genotoxicity Of The Broad Class Of Carbon Nanotubes And Nanofibers Used Or Produced In Us Facilities, Kelly Fraser, Vamsi Kodali, Naveena Yanamala, M. Eileen Birch, Lorenzo Cena, Gary Casuccio, Kristin Bunker, Traci L. Lersch, Douglas E. Evans, Aleksandr Stefaniak, Mary Ann Hammer, Michael L. Kashon, Theresa Boots, Tracy Eye, John Hubczak, Sherri A. Friend, Matthew Dahm, Mary K. Schubauer-Berigan, Katelyn Siegrist, David Lowry, Alison K. Bauer, Linda M. Sargent, Aaron Erdely 2020 West Virginia University

Physicochemical Characterization And Genotoxicity Of The Broad Class Of Carbon Nanotubes And Nanofibers Used Or Produced In Us Facilities, Kelly Fraser, Vamsi Kodali, Naveena Yanamala, M. Eileen Birch, Lorenzo Cena, Gary Casuccio, Kristin Bunker, Traci L. Lersch, Douglas E. Evans, Aleksandr Stefaniak, Mary Ann Hammer, Michael L. Kashon, Theresa Boots, Tracy Eye, John Hubczak, Sherri A. Friend, Matthew Dahm, Mary K. Schubauer-Berigan, Katelyn Siegrist, David Lowry, Alison K. Bauer, Linda M. Sargent, Aaron Erdely

Health Faculty Publications

Background Carbon nanotubes and nanofibers (CNT/F) have known toxicity but simultaneous comparative studies of the broad material class, especially those with a larger diameter, with computational analyses linking toxicity to their fundamental material characteristics was lacking. It was unclear if all CNT/F confer similar toxicity, in particular, genotoxicity. Nine CNT/F (MW #1-7 and CNF #1-2), commonly found in exposure assessment studies of U.S. facilities, were evaluated with reported diameters ranging from 6 to 150 nm. All materials were extensively characterized to include distributions of physical dimensions and prevalence of bundled agglomerates. Human bronchial epithelial cells were ...


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