The Latest And Greatest On Usp 797/800 - An Update,
2019
Miami Cancer Institute
The Latest And Greatest On Usp 797/800 - An Update, Alyssa Donadio
All Publications
No abstract provided.
Treatment Of Pulmonary Hypertension,
2019
Bethesda Hospital East
Treatment Of Pulmonary Hypertension, Lissette Bauza
All Publications
No abstract provided.
Pharmacological Management Of Cystic Fibrosis - Exploring The Therapeutic Advancements In Cystic Fibrosis,
2019
Baptist Hospital of Miami
Pharmacological Management Of Cystic Fibrosis - Exploring The Therapeutic Advancements In Cystic Fibrosis, Jessica Justiz
All Publications
No abstract provided.
Update On Anticoagulation Agents And Reversals,
2019
West Kendall Baptist Hospital
Update On Anticoagulation Agents And Reversals, Carolyn Ruiz
All Publications
No abstract provided.
Telepharmacy: The Future Of Pharmacy Services,
2019
Miami Cancer Institute
Telepharmacy: The Future Of Pharmacy Services, Monica Tadros
All Publications
No abstract provided.
Beyond The Hospital Doors - The Future Of Transitions Of Care,
2019
West Kendall Baptist Hospital
Beyond The Hospital Doors - The Future Of Transitions Of Care, Lorena Berrios Caldero
All Publications
No abstract provided.
I Can't Breathe - Cystic Fibrosis,
2019
Homestead Hospital
I Can't Breathe - Cystic Fibrosis, Mayret Gonzalez
All Publications
No abstract provided.
Where Are We With Marijuana And The Smoking Truth About Vaping?,
2019
South Miami Hospital
Where Are We With Marijuana And The Smoking Truth About Vaping?, Lorenzo Porras Jr.
All Publications
No abstract provided.
Abuse And Misuse Of Stimulants For Adhd,
2019
Baptist Hospital of Miami
Abuse And Misuse Of Stimulants For Adhd, Rita Chamoun
All Publications
No abstract provided.
Updates In The Treatment Of Alzheimer's Disease, Nothing To Forget About,
2019
Baptist Hospital of Miami
Updates In The Treatment Of Alzheimer's Disease, Nothing To Forget About, Jessica Greenwood
All Publications
No abstract provided.
Update On Epilepsy - Newer Treatment Options,
2019
Baptist Hospital of Miami
Update On Epilepsy - Newer Treatment Options, Kamarena Sankar
All Publications
No abstract provided.
Biosynthetic And Synthetic Strategies For Assembling Capuramycin-Type Antituberculosis Antibiotics,
2019
University of Kentucky
Biosynthetic And Synthetic Strategies For Assembling Capuramycin-Type Antituberculosis Antibiotics, Ashley L. Biecker, Xiaodong Liu, Jon S. Thorson, Zhaoyong Yang, Steven G. Van Lanen
Pharmaceutical Sciences Faculty Publications
Mycobacterium tuberculosis (Mtb) has recently surpassed HIV/AIDS as the leading cause of death by a single infectious agent. The standard therapeutic regimen against tuberculosis (TB) remains a long, expensive process involving a multidrug regimen, and the prominence of multidrug-resistant (MDR), extensively drug-resistant (XDR), and totally drug-resistant (TDR) strains continues to impede treatment success. An underexplored class of natural products—the capuramycin-type nucleoside antibiotics—have been shown to have potent anti-TB activity by inhibiting bacterial translocase I, a ubiquitous and essential enzyme that functions in peptidoglycan biosynthesis. The present review discusses current literature concerning the biosynthesis and chemical synthesis of capuramycin …
Cytochrome P450s And Uses Thereof,
2019
University of Kentucky
Cytochrome P450s And Uses Thereof, Joseph Chappell, Lyle F. Ralston
Pharmaceutical Sciences Faculty Patents
The invention relates to isolated cytochrome P450 polypeptides and nucleic acid molecules, as well as expression vectors and transgenic plants containing these molecules. In addition, the invention relates to uses of such molecules in methods of increasing the level of resistance against a disease caused by a plant pathogen in a transgenic plant, in methods for producing altered compounds, for example, hydroxylated compounds, and in methods of producing isoprenoid compounds.
Cytochrome P450s And Uses Thereof,
2019
University of Kentucky
Cytochrome P450s And Uses Thereof, Joseph Chappell, Lyle F. Ralston
Pharmaceutical Sciences Faculty Patents
The invention relates to isolated cytochrome P450 polypeptides and nucleic acid molecules, as well as expression vectors and transgenic plants containing these molecules. In addition, the invention relates to uses of such molecules in methods of increasing the level of resistance against a disease caused by a plant pathogen in a transgenic plant, in methods for producing altered compounds, for example, hydroxylated compounds, and in methods of producing isoprenoid compounds.
Role Of Transcription-Regulating Kinase Cdk8 In Colon Cancer Metastasis,
2019
Department of Drug Discovery and Biomedical Sciences, University of South Carolina
Role Of Transcription-Regulating Kinase Cdk8 In Colon Cancer Metastasis, Jiaxin Liang, Mengqian Chen, Eugenia Broude, Igor Roninson
Faculty Publications
No abstract provided.
The Promises And Challenges Of Erythropoietin For Treatment Of Alzheimer's Disease,
2019
Keck Graduate Institute
The Promises And Challenges Of Erythropoietin For Treatment Of Alzheimer's Disease, Jiahong Sun, Jan Michelle Martin, Victoria Vanderpoel, Rachita K. Sumbria
Pharmacy Faculty Articles and Research
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder in the world, and intracellular neurofibrillary tangles and extracellular amyloid-beta protein deposits represent the major pathological hallmarks of the disease. Currently available treatments provide some symptomatic relief but fail to modify primary pathological processes that underlie the disease. Erythropoietin (EPO), a hematopoietic growth factor, acts primarily to stimulate erythroid cell production, and is clinically used to treat anemia. EPO has evolved as a therapeutic agent for neurodegeneration and has improved neurological outcomes and AD pathology in rodents. However, penetration of the blood–brain barrier (BBB) and negative hematopoietic effects are the two …
January 2019,
2019
Southwestern Oklahoma State University
January 2019, Randy Curry, Cindy Brooks
RURAL ROCKS
Rural Rocks, the Rural Health Network newsletter by the SWOSU College of Pharmacy
Developing A Biased Unmatched Bivalent Ligand (Bumbl) Design Strategy To Target The Gpcr Homodimer Allosteric Signaling (Camp Over Β-Arrestin 2 Recruitment) Within The Melanocortin Receptors.,
2019
Nova Southeastern University
Developing A Biased Unmatched Bivalent Ligand (Bumbl) Design Strategy To Target The Gpcr Homodimer Allosteric Signaling (Camp Over Β-Arrestin 2 Recruitment) Within The Melanocortin Receptors., Cody J Lensing, Katie T Freeman, Sathya M Schnell, Robert Charles Speth, Adam T Zarth, Carrie Haskell-Luevano
Faculty Articles
Understanding the functional relevance of G protein-coupled receptor (GPCR) homodimerization has been limited by the insufficient tools to assess asymmetric signaling occurring within dimers comprised of the same receptor type. We present unmatched bivalent ligands (UmBLs) to study the asymmetric function of melanocortin homodimers. UmBLs contain one agonist and one antagonist pharmacophore designed to target a melanocortin homodimer such that one receptor is occupied by an agonist and the other receptor by an antagonist pharmacophore. First-in-class biased UmBLs (BUmBLs) targeting the human melanocortin-4 receptor (hMC4R) were discovered. The BUmBLs displayed biased agonism by potently stimulating cAMP signaling (EC
Biopharmaceutics And Physical Pharmacy Bps 307,
2019
University of Rhode Island
Biopharmaceutics And Physical Pharmacy Bps 307, Joanna Burkhardt
Library Impact Statements
No abstract provided.
Bishydrazone-Based Antifungal Agents,
2019
University of Kentucky
Bishydrazone-Based Antifungal Agents, Sylvie Garneau-Tsodikova, David S. Watt
Pharmaceutical Sciences Faculty Patents
Hydrazone compounds and pharmaceutical compositions including same are disclosed as having antifungal activity. Such compounds are useful for treating or preventing fungal conditions in a subject in need thereof by administering same.
