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Amixicile, A Novel Antimicrobial Agent, And Its Effect On The Salivary And Subgingival Microbiome In Rhesus Macaque Monkeys, Erin E. Block 2021 Virginia Commonwealth University

Amixicile, A Novel Antimicrobial Agent, And Its Effect On The Salivary And Subgingival Microbiome In Rhesus Macaque Monkeys, Erin E. Block

Theses and Dissertations

Background/Purpose: Periodontitis is an inflammatory disease with a bacterial etiology in a susceptible host. A selective antibiotic with minimal systemic side effects could be a useful adjunct to traditional periodontal therapy. Amixicile is a novel antimicrobial agent that targets pyruvate: ferredoxin oxidoreductase (PFOR), an enzyme that is critical for anaerobic bacterial metabolism and has been found to have little-to-no side-effects in animal models. The aim of this study was to prospectively evaluate the effect of amixicile on clinical periodontal parameters and the composition of the oral microbiome in rhesus macaque monkeys. It was hypothesized that the amixicile would reduce growth …


Antibiotic-Loaded Dendrimer Hydrogels In Periodontal Bone Regeneration: A Feasibility Study, Nicholas G. Yesbeck 2021 Virginia Commonwealth University

Antibiotic-Loaded Dendrimer Hydrogels In Periodontal Bone Regeneration: A Feasibility Study, Nicholas G. Yesbeck

Theses and Dissertations

Purpose: Prescription of a complete course of oral antibiotics following bone grafting procedures is a common clinical practice in surgical periodontics. Prophylactic administration of antibiotics reduces the risk of surgical site infection and systemic administration is preferred over local delivery because of short duration of action in the latter circumstance. The goal of this study is to demonstrate the ability of dendrimer hydrogels (DH) to prolong the release kinetics of antibiotics in-vitro. A secondary goal will be to analyze the effect of different particulate bone allografts on the release kinetics of the antibiotic.

Methods: Dendrimer hydrogels (DH) were synthesized …


Trimming And Ph Effects On Nickel Ion Release From Stainless Steel Crowns Of Primary Teeth, Milad Arab-Nozari, Mohammad Shokrzadeh, Nastaran Zamehran, Jamshid Yazdani Charati, Azam Nahvi 2020 Department of Toxicology and Pharmacology, Faculty of Pharmacy, Islamic Azad University, Ayatollah Amoli Branch, Amol, Iran.

Trimming And Ph Effects On Nickel Ion Release From Stainless Steel Crowns Of Primary Teeth, Milad Arab-Nozari, Mohammad Shokrzadeh, Nastaran Zamehran, Jamshid Yazdani Charati, Azam Nahvi

Journal of Dentistry Indonesia

Objective: Stainless steel crowns (SSCs) are preformed metal crowns used to restore severely decayed primary teeth. The aim of this study is to evaluate the effects of pH changes and SSC margin trimming on nickel release in artificial saliva solution. Methods: A total of 90 SSCs were divided into three groups and placed in 35 ml of artificial saliva of pH 6.8, 5, and 3.5. Another group consisting 30 SSCs with trimmed margins was placed in saliva of pH 6.8. All SSCs were incubated at 37°C. The concentration of released nickel was assessed on days 1, 7, 14, 21, and …


Evaluation Of Maxillary Impacted Teeth And Their Relationship With Adjacent Teeth And Anatomic Structures With Cone Beam Computed Tomography, Emre Köse, Emin Murat Canger 2020 Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Aydin Adnan Menderes University, Aydin, Turkey

Evaluation Of Maxillary Impacted Teeth And Their Relationship With Adjacent Teeth And Anatomic Structures With Cone Beam Computed Tomography, Emre Köse, Emin Murat Canger

Journal of Dentistry Indonesia

Objective: This study aimed to examine the cone beam computed tomography (CBCT) images of impacted maxillary canines and mesiodentes. Methods: This retrospective radiographic study was performed on 177 patients with 200 impacted maxillary canines and 12 mesiodentes. Using CBCT images, the unilateral/bilateral occurrence, presence of root dilaceration, mesio-distal and buccopalatal location, impaction condition, contact region of adjacent teeth, presence and degree of root resorption of adjacent teeth, dental follicle width, closest distance to the nasal cavity, nasopalatinal canal, and maxillary sinus were assessed. For mesiodentes, the types, follicle width, direction, and relationship with anatomical structures were evaluated. Results: No statistical …


Comparative Evaluation Of Apical Extrusion Debris And Irrigant During Calcium Hydroxide Removal And Endodontic Instrumentation Using Three Types Of Instrumentation Systems, Selen İnce Yusufoğlu, Esma Saricam 2020 Department of Endodontics, Faculty of Dentistry , Ankara Yıldırım Beyazıt University, Ankara, Turkey

Comparative Evaluation Of Apical Extrusion Debris And Irrigant During Calcium Hydroxide Removal And Endodontic Instrumentation Using Three Types Of Instrumentation Systems, Selen İnce Yusufoğlu, Esma Saricam

Journal of Dentistry Indonesia

Many root canal preparation techniques and instruments produce apically extruded materials to a certain extent depending on the preparation system adopted. The extrusion of debris from the apical foramen during chemomechanical preparation may cause postoperative pain and failure of endodontic treatment. Objective: This study evaluates the differences in the apical extrusion of debris and calcium hydroxide (CH) during endodontic instrumentation by using Reciproc Blue (RB), WaveOne Gold (WOG), and F6 Skytaper (F6). Methods: Six experimental study groups (n = 13) were established. The root canal procedures for all groups were prepared with different methods: Group I: One Shape (OS) instrumentation, …


Reliability Of Panoramic Radiography For Vertical Facial Pattern Assessment, Waqar Jeelani, Maheen Ahmed, Shakeel Ahmed 2020 Department of Orthodontics, Bakhtawar Amin Medical and Dental College, Multan, Pakistan

Reliability Of Panoramic Radiography For Vertical Facial Pattern Assessment, Waqar Jeelani, Maheen Ahmed, Shakeel Ahmed

Journal of Dentistry Indonesia

The orthopantomogram (OPG) is a common dental screening radiograph that has multiple implications. However, lateral cephalogram is the investigation of choice for the assessment of vertical facial pattern. Objective: The aim of the current study was to investigate the validity of an OPG parameter i.e. panoramic gonial angle (PGoA) for the assessment of the vertical facial pattern. Methods: A cross-sectional study was conducted on the pretreatment OPG and lateral cephalograms of 200 orthodontic patients aged 15-40 years. The PGoA was measured on both sides and an average was used for statistical analysis. The Pearson’s correlations of PGoA were measured with …


Effect Of Salivary Ph On Water Absorption And Solubility Of Enhanced Resin- Modified Glass Ionomer, Yosi Kusuma Eriwati, Muhammad Dhiaulfikri, Ellyza Herda 2020 Department of Dental Material Science, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia

Effect Of Salivary Ph On Water Absorption And Solubility Of Enhanced Resin- Modified Glass Ionomer, Yosi Kusuma Eriwati, Muhammad Dhiaulfikri, Ellyza Herda

Journal of Dentistry Indonesia

The influence of immersion period and liquid pH on water absorption capacity and solubility of the resin-modified glass ionomer cement (RMGIC) raises the question of whether the critical pH of hydroxyapatite and fluoroapatite influences the water absorption capacity and solubility of enhanced resin-modified glass ionomer (ERMGI). Objective: This study was designed to investigate the effects of immersion periods and various pH levels of artificial saliva on the water absorption and solubility of RMGIC and ERMGI. Methods: Fifty-four disc-shaped specimens (15 mm x 1 mm) of enhanced RMGI (ACTIVATM BioACTIVE-RESTORATIVE, Pulpdent, Watertown, MA, USA) and 54 disc-shaped specimens (15 mm x …


Self-Assessment Tool For Evaluating Periodontal Conditions, Haslina Rani, Tuti Ningseh Mohd-Dom, Shahida Mohd-Said, Nur Azwani Johari 2020 Department of Family Oral Health, Faculty of Dentistry, The National University of Malaysia, Bangi 43600, Malaysia

Self-Assessment Tool For Evaluating Periodontal Conditions, Haslina Rani, Tuti Ningseh Mohd-Dom, Shahida Mohd-Said, Nur Azwani Johari

Makara Journal of Health Research

Background: The global prevalence of periodontal disease is steadily rising. Early detection through the active screening of potential patients is important because periodontal disease leads to high disease, clinical, and economic burdens. The aim of this study is to develop a simple periodontal assessment tool for the Malay-speaking population; this tool is referred to in this work as MyGusi.

Methods: Translation and back-translation of a self-assessment tool containing 10 items related to periodontal health conditions and risk behaviors were conducted by three bilingual translators. Nine periodontists were selected to determine the content validity of the tool. After pre-testing …


Radiographic Evaluation Of Bone And Mucosa Using Low-Dose Cbct With Radiopaque X-Resin Stent Versus Ct And Ridge Mapping: A Validity Study, Enji Ahmed, Nader Nabil Riskallah, Mushira Muhammed Dahaba, Eman Abdelaziz Ahmed 2020 The British University in Egypt

Radiographic Evaluation Of Bone And Mucosa Using Low-Dose Cbct With Radiopaque X-Resin Stent Versus Ct And Ridge Mapping: A Validity Study, Enji Ahmed, Nader Nabil Riskallah, Mushira Muhammed Dahaba, Eman Abdelaziz Ahmed

Dentistry

Aim: To compare the abilities of computed tomography (CT), cone beam computed tomography (CBCT) with X-resin and ridge mapping and to measure the thickness of bone and soft tissue during implant planning, which allows increasing the success criteria of implant placement. Materials and Methods: This validity study included a total of 96 samples chosen from 20 patients undergoing implant surgeries (mandible and maxilla) aged between 25 and 50 years. Measurements of bone and mucosa were done by using three techniques, which are the CT, CBCT with X-resin, and finally ridge mapping at 4 points that are 3, 4, 5, and …


Assessing Nurse Practitioners' Knowledge And Clinical Practice With Regard To The Oral-Systemic Link, Angela Haynes 2020 East Tennessee State University

Assessing Nurse Practitioners' Knowledge And Clinical Practice With Regard To The Oral-Systemic Link, Angela Haynes

Electronic Theses and Dissertations

Nurse Practitioners (NPs) comprise a significant portion of the U.S. primary care workforce and play an essential role in patients' health awareness, prevention strategies, disease management, and in providing appropriate provider referrals. Nurse Practitioners receive education on the oral-systemic connection, yet there have been limited studies on the clinical practice of NPs assessing the oral cavity to evaluate the condition of the teeth and the oral tissues. The purpose of this study was to explore the nurse practitioners’ knowledge and practice habits of assessing the oral cavity for diseases or abnormalities in the mouth that can, in turn, affect overall …


Nanomaterials And Nanorobotics In Dentistry: A Review, Yelda Kasimoglu, Derya Tabakcilar, Zeynep A. Guclu, Seiko Yamamoto-Nemoto, Elif B. Tuna, Bugra Ozen, Tamer Tuzuner, Gökhan Ince 2020 Istanbul University, Faculty of Dentistry, Department of Pedodontics, Istanbul, Turkey,

Nanomaterials And Nanorobotics In Dentistry: A Review, Yelda Kasimoglu, Derya Tabakcilar, Zeynep A. Guclu, Seiko Yamamoto-Nemoto, Elif B. Tuna, Bugra Ozen, Tamer Tuzuner, Gökhan Ince

Journal of Dentistry Indonesia

Nanotechnology is a branch of science focusing on the manipulation of materials measured on the nanoscale (size = 1–100 nm). Recent advances in the field of nanodentistry have resulted in the development of alternative treatment plans for common dental problems, bringing about a paradigm shift in dentistry. Nanorobots, also known as “nanites” or “nanomachines,” are theoretical microscopic devices that may be used for the diagnosis and treatment of oral health problems. This paper aims to discuss the latest innovations in the field of nanodentistry.


Effect Of Short- And Long-Term Use Of Home And In-Office Bleaching With Carbamide Peroxide And Hydrogen Peroxide On Enamel Microhardness, Nazila Ameli, Niloofar Kianvash Rad, Farzane Nikpour, Raheb Ghorbani, Shadi Mohebi 2020 Department of Orthodontics, Dental School, Semnan University of Medical Sciences, Semnan, Iran

Effect Of Short- And Long-Term Use Of Home And In-Office Bleaching With Carbamide Peroxide And Hydrogen Peroxide On Enamel Microhardness, Nazila Ameli, Niloofar Kianvash Rad, Farzane Nikpour, Raheb Ghorbani, Shadi Mohebi

Journal of Dentistry Indonesia

Bleaching is a well-known esthetic dental treatment performed to lighten the tooth shade. Among different cosmetic dental procedures, including direct and indirect tooth-colored restorations, bleaching is likely the most conservative approach. Bleaching has been accepted well by patients and proven as a safe and effective approach. Objective: Tooth bleaching can be conducted at home or in offices. This study was performed to compare the enamel microhardness before bleaching and one and eight weeks after the application of different bleaching agents. Methods: Forty human premolars were randomly divided into four groups, and their buccal surface underwent a Vickers microhardness test …


Oral Rehabilitation Of A Patient With Congenital Erythropoietic Porphyria: A Rare Case Report, Raif Alan, Hakkı Çelebi, Fahriye Kilinc, Recep Dursun 2020 Department of Periodontology, Faculty of Dentistry, Canakkale Onsekiz Mart University, 17100, Canakkale, Turkey

Oral Rehabilitation Of A Patient With Congenital Erythropoietic Porphyria: A Rare Case Report, Raif Alan, Hakkı Çelebi, Fahriye Kilinc, Recep Dursun

Journal of Dentistry Indonesia

Congenital erythropoietic porphyria (CEP) is an extremely rare disorder involved in chronic porphyrias. One of the recommended evaluations to determine disease severity and needs of a person with CEP is dental assessment. Objective: To present a case of CEP and its oral rehabilitation. Case Report: A 32-year-old female patient was admitted to the clinic with hyperkeratinization, skin fragility, fissures, and wounds in her perioral region and hands. Intraoral gingival bleeding, mucogingival stress, and missing teeth were recorded. After medical consultation, phase I and II periodontal therapies were performed. The patient expressed satisfaction of the results of the procedures in terms …


Treatment Of A Class I Malocclusion With Severe Crowding Using Passive Self-Ligating Brackets, Agita Pramustika, Retno Widayati 2020 Orthodontics Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia

Treatment Of A Class I Malocclusion With Severe Crowding Using Passive Self-Ligating Brackets, Agita Pramustika, Retno Widayati

Journal of Dentistry Indonesia

Presently, dental crowding is the most common problem among orthodontic patients. The prevalence of crowding in the dental arch is significantly increased in modern dentitions, and it is the most common reason why patients pursue orthodontic treatment. Objective: To report an advanced bracket systems, namely self-ligating brackets, to increase the efficacy of orthodontic treatment especially in patients with severe crowding. Case Report: A 22-year-old female patient presented with severe crowding of the maxillary and mandibular arches. In the upper arch, both second premolars were palatally positioned; in the lower arch, the lower right canine was lingually positioned and the lower …


Direct Composite Resin Restoration Of Anterior Maxillary Teeth And Esthetic Smile Design: A Case Report, Christina Widya Nugrohowati, Wignyo Hadriyanto, Tunjung Nugraheni 2020 Department of Conservative Dentistry, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia

Direct Composite Resin Restoration Of Anterior Maxillary Teeth And Esthetic Smile Design: A Case Report, Christina Widya Nugrohowati, Wignyo Hadriyanto, Tunjung Nugraheni

Journal of Dentistry Indonesia

Dental esthetic complex involves more than one caries with malformed shape and malposition. Dental trauma most commonly affects maxillary anterior teeth, and subsequently affects the esthetics, functions, and psychological well-being of the individual. Composite resins have become an integral part of contemporary restorative and minimally invasive dentistry. Objective: To summarize the successful use of direct composite resin restoration in the management of a 29-year old male patient. Case Report: A 29-year old male patient presenting with multiple secondary caries and crown fractures in the anterior maxillary teeth, resulting in an unaesthetic smile. Comprehensive esthetic dental treatment was carried out. The …


J Mich Dent Assoc June 2020, 2020 American Dental Association

J Mich Dent Assoc June 2020

The Journal of the Michigan Dental Association

Every month,The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

  • A cover story with an interview with the MDA’s 2020-21 president Dr. Stephen Meraw.
  • “Implementing Teledentistry: The Why and How” discusses the background and guidance on this important – and growing – aspect of telehealth.
  • “Key Tips in Communicating Evidence in the Clinical Setting”, another feature in our series of articles focusing on evidence-based dentistry. …


Commentary: Phytocannabinoids As Therapeutic Agents To Combat Chronic Gingival Disease., Nick Narek Ohanian 2020 Arthur A. Dugoni School of Dentistry University of the Pacific

Commentary: Phytocannabinoids As Therapeutic Agents To Combat Chronic Gingival Disease., Nick Narek Ohanian

Pacific Journal of Health

The therapeutic potential of cannabis has been harnessed for thousands of years yet the United States Food and Drug Administration (FDA) has still not approved cannabis as a safe or effective drug. The FDA has, however, approved the manufacturing of pharmaceutical drugs, which contain a “synthetic version of a substance that is present in the marijuana” and other compounds that mimic its action. A search of the US National Library of Medicine and National Institute of Health for keywords “CBD” and “Periodontitis” together yields only 2 publications. Although the current State and Federal regulations on the use of cannabis for …


Comparison Of Heat Generated During Twist Drilling Protocol By Guided And Non-Guided Implant Surgery, Joshua Lee 2020 Loma Linda University

Comparison Of Heat Generated During Twist Drilling Protocol By Guided And Non-Guided Implant Surgery, Joshua Lee

Loma Linda University Electronic Theses, Dissertations & Projects

Introduction: Guided implant surgery is becoming more prevalent among clinicians and is crucial for cases in which there are concerns about the proximity of the implant to vital anatomical structures, esthetic concerns, and the amount/quality of bone available. Surgical guides help with the angulation and positioning of the implant through the use of a CBCT scan and digital intraoral impression. However, there are some drawbacks with guided surgery. Heat that is generated during the osteotomy is one of the issues that has been of concern. The guide acts as a shield against the water irrigation from reaching the osteotomy …


A Comparison Of Heat Generated Between Carbide And Diamond Bur During Implantoplasty, Bryce Chun 2020 Loma Linda University

A Comparison Of Heat Generated Between Carbide And Diamond Bur During Implantoplasty, Bryce Chun

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose: This study was conducted to evaluate heat generated during the implantoplasty procedure by comparing the heat generated using either a carbide or diamond round bur. Materials and Methods: Bovine ribs were selected as the osseous model for this study. Changes in temperature were measured using a digital thermometer (Extech SDL200 four channel thermometer, Extech instruments, Melrose MA). Ther k-thermocouples were positioned within the implant screw access, apex of the implant, and crestal bone adjacent to the implant and ambient air. 5 bovine rib bone blocks were prepared by place 5 cylindrical titanium grade 5 alloy large grit sand blasted …


Demographic And Clinical Profile Of Gingival Oral Lichen Planus In A Group Of Thai Individuals, Pissacha Daroonpan, Ruchadaporn Kaomongkolgit, Weeraya Tantanapornkul, Jadesada Palasuk 2020 Department of Oral Diagnosis, Faculty of Dentistry, Naresuan University, Phitsanulok 65000, Thailand

Demographic And Clinical Profile Of Gingival Oral Lichen Planus In A Group Of Thai Individuals, Pissacha Daroonpan, Ruchadaporn Kaomongkolgit, Weeraya Tantanapornkul, Jadesada Palasuk

Journal of Dentistry Indonesia

Objective: This study aimed to determine the clinical profile of the gingival lesions of oral lichen planus (OLP) in a group of Thai patients. Methods: The dental records of 67 patients were reviewed. Results: In this study, 51 (76.1%) women and 16 (23.9%) men with a female-to-male ratio of 3.2:1 were included. The average age of patients with OLP was 56.0 ± 12.5 years (ranged = 20–81 years). Furthermore, 52 (77.6%) patients had a history of systemic diseases, and hypertension was predominant. All the patients presented with symptomatic OLP. Multiple OLP lesions were observed in 56 (83.6%) …


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