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Prevalence And Oral Health-Related Factors Associated With Mild Cognitive Impairment In Elderly Dental Patients At Faculty Of Dentistry, Chulalongkorn University, Panatcha Weerapol 2019 Faculty of Dentistry

Prevalence And Oral Health-Related Factors Associated With Mild Cognitive Impairment In Elderly Dental Patients At Faculty Of Dentistry, Chulalongkorn University, Panatcha Weerapol

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aims to assess the prevalence of Mild Cognitive Impairment (MCI) and its oral health-related factors in elderly dental patients at Geriatric dentistry clinic and Prosthodontic clinic of Faculty of Dentistry, Total 248 dental patients aged 60 years and above were recruit. Average age of participants was 68.68 years with 73.0 % female. Cognitive functions were assessed by Montreal Cognitive Assessment Thai version (MoCA-T). Individual data were obtained by self-reported interview. Oral examinations were evaluated by a dentist. The prevalence of MCI was found 29.4% in elderly dental patients and was higher than among general elders. Oral health-related factors …


Dental Services Utilization, Oral Status, And Oral Health-Related Quality Of Life Among Thai Elderly: Data From The Eight Thailand National Oral Health Survey, Punkanit Harirugsakul 2019 Faculty of Dentistry

Dental Services Utilization, Oral Status, And Oral Health-Related Quality Of Life Among Thai Elderly: Data From The Eight Thailand National Oral Health Survey, Punkanit Harirugsakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

The number of older adults in Thailand is currently increasing. To create the appropriate oral health service for them requires understanding the associations between dental service utilization (DSU), oral status and oral health-related quality of life (OHRQoL). The objectives of this study were to examine the associations of DSU and oral status with OHRQoL and to examine the associations between social backgrounds and DSU in Thai older adults. Data on 4,130 Thai older adults from the 8th Thailand National Oral Health Survey were collected through interviews and oral examination. Chi-square test and multiple logistic regression models were applied. Thai older …


A Comparison Of Microrna Profiles Between Rat Incisors And Molars, Sirawit Nipakasem 2019 Faculty of Dentistry

A Comparison Of Microrna Profiles Between Rat Incisors And Molars, Sirawit Nipakasem

Chulalongkorn University Theses and Dissertations (Chula ETD)

Unlike the molar, rodent incisor is a distinct organ that have continuously growth at distal end of tooth throughout its lifetime to compensate for abrasion. The key of continuous growth is the result of delayed root formation and prolonged crown formation that possibly made by stem cell niche, so-called cervical loop, which involve various genes and signaling pathways. MicroRNAs (miRNAs) are small non-coding single stranded RNAs that involved in biological mechanisms of dental development. To study the role of miRNA, we extracted total RNA from the dental pulp tissue collected from the apical part, coronal part of incisors and molars, …


Oral Health-Related Quality Of Life And Related Factors In The Elderly Patients Who Received Dental Treatment, Teerawut Tatiyapongpaiboon 2019 Faculty of Dentistry

Oral Health-Related Quality Of Life And Related Factors In The Elderly Patients Who Received Dental Treatment, Teerawut Tatiyapongpaiboon

Chulalongkorn University Theses and Dissertations (Chula ETD)

This thesis is a cross-sectional study which explores underlying determinants of elderly patients. The study examines related factor that impaired Oral Health-related Quality of life (OHRQoL) and analyzes the characteristics of elderly patients at our clinic. 46 participants are patients who completed dental treatment more than 6 months during May 2016 to December 2018. Underlying determinants information were recorded by interview, patient chart review and oral examination. There were collected self-evaluation and Oral Impacts on Daily Performances (OIDP). Descriptive statistics was used to describe the characteristics of patients. Spearman correlation and Kruskal-Wallis test at P-value < 0.05 were performed. From the results, the participant’s OIDP scores showed the majority in no severity and no more than 2 impacts activities. The major activities that were impacted were eating activity and speaking activity due to ill-fitting dentures but less impacts in psychological and social performance. There was poor denture satisfaction that impaired participant’s OHRQoL. However, there were differences between dentist and patient evaluation. The authors suggest that the dental treatment should focus on the recall system, the frequency of dental recall visits, procedures to successful oral hygiene instruction and skills to handle the denture problems.


The Study Of Oro-Dental Structures And Application Of Dental Adhesives In Patients Affected With Osteogenesis Imperfecta, Oadcharawadee Nutchoey 2019 Faculty of Dentistry

The Study Of Oro-Dental Structures And Application Of Dental Adhesives In Patients Affected With Osteogenesis Imperfecta, Oadcharawadee Nutchoey

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: To investigate genetic mutations, oro-dental features, tooth ultrastructures, and characteristics of total-etch adhesives (Optibond FL; Kerr) and self-etch adhesives (Clearfill SE Bond; Kuraray) applied on the teeth of the patients who affected with syndromic osteogenesis imperfecta and dentiongenesis imperfecta(DGI), compared with the controls. Methods: Three patients were diagnosed with osteogenesis imperfecta and dentinogenesis imperfecta at Faculty of Medicine, Clinical, radiographic, and laboratory examination were performed. Genetic mutations were analyzed by whole-exome sequencing (WES) and Sanger sequencing. Three teeth were obtained, one tooth from each patient (DGI tooth). Each tooth sample was examined for its color by colorimeter, mineral composition …


Proximal Caries Detection On Smartphone Display, Napas Lappanakokiat 2019 Faculty of Dentistry

Proximal Caries Detection On Smartphone Display, Napas Lappanakokiat

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aim of this study was to compare diagnostic accuracy in proximal caries detection between bitewing radiographs exported from PACS software and taken with a smartphone viewed in a smartphone display. A total of 200 proximal surfaces from digital bitewing radiographs were included in this study. Images of all radiographs were captured from a medical-grade and a common display by an iPhone 8 Plus and stored as JPEG files. Exported DICOM files were converted into JPEG format and transferred to the smartphone used for image capturing. Each proximal surface was rated by 7 observers with 5-point-scale. Weighted kappa test was …


The Efficacy Of Vitamin C Oral Supplement On Wound Healing After Tooth Extraction, Nanthanut Pisalsitsakul 2019 Faculty of Dentistry

The Efficacy Of Vitamin C Oral Supplement On Wound Healing After Tooth Extraction, Nanthanut Pisalsitsakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: The purpose of this study was to evaluate the effect and proper dosage of oral vitamin C supplement on post-extraction wound healing. Methods: This study was a split mouth, double-blind, randomized-controlled clinical trial of 42 patients who underwent symmetric bilateral non-infected premolars extraction. The patients were randomly divided into 3 groups (14 patients for each group); 1.placebo vs vitamin C 600 mg/d, 2.placebo vs vitamin C 1,500 mg/d and 3.vitamin C 600 mg/d vs vitamin C 1,500 mg/d. Each group was prescribed placebo and/or vitamin C three times a day for 10 days after each tooth extraction. The assessment …


Use Of Digital Panoramic Radiographs As A Screening Tool For Diagnosis Of Osteoporosis In Thai Postmenopausal Women, Net-nada Chongruangsri 2019 Faculty of Dentistry

Use Of Digital Panoramic Radiographs As A Screening Tool For Diagnosis Of Osteoporosis In Thai Postmenopausal Women, Net-Nada Chongruangsri

Chulalongkorn University Theses and Dissertations (Chula ETD)

Purpose: To investigate the correlation between panoramic radiographic indices and osteoporosis, and to determine whether digital panoramic radiographs could be used as a screening tool for the diagnosis of osteoporosis in Thai postmenopausal women. Materials and Methods: A cross-sectional study of sixty Thai postmenopausal women with and without osteoporosis. The subjects were divided into three groups based on diagnosis by dual-energy X-ray absorptiometry (DXA): normal, osteopenia, and osteoporosis equally in each group. The panoramic radiographic indices measured were mental index (MI) and mandibular cortical index (MCI). Pearson’s correlation test was performed to analyze any correlation between MI, MCI, and BMD …


Association Between Clinical Signs And Quality Of Life In Thai Patients With Oral Lichen Planus, Sasirin Yiemstan 2019 Faculty of Dentistry

Association Between Clinical Signs And Quality Of Life In Thai Patients With Oral Lichen Planus, Sasirin Yiemstan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Subjective patient’s symptoms and oral health-related quality of life (OHRQoL) were recommended to be involved in oral lichen planus (OLP) studies. Objectives: to evaluate 1) the association between OLP clinical signs and OHRQoL as well as pain perception. 2) the association between OLP pain and OHRQoL. Methods: Sixty-nine OLP or oral lichenoid drug reaction (OLDR) Thai patients were recruited. Data were collected through personal interview with the Numeric Rating Scale (NRS) and Thai version of Oral Impacts on Daily Performance (OIDP) index. OLP signs were examined in aspects of localization, type and clinical severity according to the Thongprasom sign scoring …


Clinical Evaluation Of Two Glass Ionomer Cement Restorations Placed In Primary Molars With Atraumatic Restorative Treatment Technique: A Randomized Controlled Trial., Manarin Boonyawong 2019 Faculty of Dentistry

Clinical Evaluation Of Two Glass Ionomer Cement Restorations Placed In Primary Molars With Atraumatic Restorative Treatment Technique: A Randomized Controlled Trial., Manarin Boonyawong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: The purpose of this study was to compare clinical success of a novel material (silver diamine fluoride incorporated with high-viscosity glass ionomer cement (SDF-GIC)) in Class II restoration in primary molars using atraumatic restorative treatment (ART) technique at 6- and 12- month follow-up. Materials and Methods: A randomized controlled clinical trial using a parallel group design was carried out on 150 children aged 3-8 years old, from 5 public school in Samut Sakhon province, Thailand, with at least one class II cavities. They were randomly allocated to two treatment groups: ART restoration using either GIC (Fuji IX GP) or …


Protein Expression And Inflammatory Response After Delivery Of Mrna Encoding Platelet-Derived Growth Factor-Bb In Sucrose Citrate Buffer Into Rat Gingiva, Phan Bhongsatiern 2019 Faculty of Dentistry

Protein Expression And Inflammatory Response After Delivery Of Mrna Encoding Platelet-Derived Growth Factor-Bb In Sucrose Citrate Buffer Into Rat Gingiva, Phan Bhongsatiern

Chulalongkorn University Theses and Dissertations (Chula ETD)

Messenger RNA (mRNA) has emerged as a novel therapeutic modality in medical fields, including regenerative medicine. The concept of mRNA-based therapy is to use synthesized mRNA encoding therapeutic protein delivered to target tissue. Thus, mRNA encoding growth factor could be a promising alternative to recombinant protein. Platelet-derived growth factor (PDGF) is one of most extensively studied growth factors for periodontal regeneration. To date, mRNA therapy has never been explored in the field of periodontal regeneration. The aim of the study is to examine the effect of nucleoside-modified mRNA encoding PDGF-BB on the level of PDGF-BB protein and inflammatory response at …


The Use Of Modified Mrna Encoding Platelet-Derived Growth Factor-Bb As An Innovation In Periodontal Regeneration, Theeraphat Surisaeng 2019 Faculty of Dentistry

The Use Of Modified Mrna Encoding Platelet-Derived Growth Factor-Bb As An Innovation In Periodontal Regeneration, Theeraphat Surisaeng

Chulalongkorn University Theses and Dissertations (Chula ETD)

Since the mRNA platform has been recently introduced to several fields in medicine and the achievement of periodontal regeneration is currently unpredictable, therefore, the use of mRNA technology is a promising approach to pursue the complete periodontal regeneration. The aims of this study are to learn if mRNA encoding platelet-derived growth factor-BB (PDGF-BB) induces PDGF production in human periodontal ligament cells (PDLCs) and to investigate the effect of secreted PDGF on PDLC proliferation and promoting endothelial cell tube formation. PDLCs were obtained from extracted teeth of healthy periodontal patients. The N1-methylpseudouridine modified mRNA encoding PDGF-BB were transfected into PDLCs. The …


The Effect Of Change In Medi-Cal Dental Coverage On Dental Care Utilization Among Medi-Cal Beneficiaries, Min H. Zhang 2019 Virginia Commonwealth University

The Effect Of Change In Medi-Cal Dental Coverage On Dental Care Utilization Among Medi-Cal Beneficiaries, Min H. Zhang

Theses and Dissertations

One of the most important factors in accessing dental care is having dental insurance. For people with low incomes, Medicaid is the main source of health insurance. Medi-Cal is California’s Medicaid program. Adult dental services were mostly eliminated in Medi-Cal in 2009 due to the economic downturn and partially restored in 2014. The objective of this study is to evaluate the effect of change in Medi-Cal dental coverage, specifically the partial restoration of adult dental coverage in 2014, on dental care utilization among Medi-Cal beneficiaries. The partial restoration significantly increased the utilization rates in dental clinics from 2014 to 2017 …


The Effect Of Quercetin In Periodontal Inflammation, Sara Holden 2019 Virginia Commonwealth University

The Effect Of Quercetin In Periodontal Inflammation, Sara Holden

Theses and Dissertations

Purpose: To determine the effect of Quercetin, a plant based over the counter flavonoid, on periodontal inflammation in a murine model of periodontitis.

Methods: Periodontitis was induced in age and gender matched mice (C57BL/6) using ligatures on the left side of the maxilla and right side was left un-ligated as baseline control. The animals received daily Quercetin gavage or Phosphate Buffered Saline (PBS) starting 5 days prior to ligation which continued throughout the experimental protocol. Micro-computed tomography (micro CT) imaging was used to determine alveolar bone loss. Real Time quantitative (qRT) PCR was used to determine level of gingival tissue …


The Effect Of Occlusal Pressure On Vertical Force Generation On Dentate And Edentulous Subjects, Matthew Thomas Harper 2019 WVU School of Dentistry

The Effect Of Occlusal Pressure On Vertical Force Generation On Dentate And Edentulous Subjects, Matthew Thomas Harper

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objectives: To determine 1) the difference in lower extremity power obtained from a vertical jump in individuals who are dentate or edentulous (implants or dentures) and 2) the difference occlusal pressure makes on lower body force output. Variables included jump height, maximum kicking force, maximum push off force, take off velocity, flight time, jump impulse, and maximum velocity. Groups included dentate, implant overdenture, and conventional denture.

Methods: Counter movement jumping with force plate collection was utilized to test the three populations in this study. The three populations were dentate, mandibular implant overdenture opposing maxillary complete denture, and conventional maxillary and …


Impact On The Pharyngeal Airway Space After Maxillomandibular Advancement Procedure For Obstructive Sleep Apnea Patients, Ghaddy AlSaty 2019 WVU

Impact On The Pharyngeal Airway Space After Maxillomandibular Advancement Procedure For Obstructive Sleep Apnea Patients, Ghaddy Alsaty

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: Obstructive sleep apnea (OSA) is a sleep-related breathing disorder, characterized by disrupted snoring and repetitive upper airway obstructions. Continuous positive airway pressure (CPAP) is considered the therapeutic mainstay for OSA patients. However, CPAP therapy has compliance limitations. An alternative treatment options is maxillomandibular advancement (MMA) surgical procedure. Genial tubercle advancement (GTA) is often performed concomitant with MMA for esthetic purposes. Cone-beam computed tomography (CBCT) provides the ability to visualize the upper airway and perform three-dimensional (3D) reconstructions. The purpose of this study is to evaluate the impact of MMA procedure with or without GTA on oropharyngeal …


Effect Of Shear Bond Strength With Novel Apc™ Flash-Free Brackets And Different Bonding Protocol: An In Vitro Study, Carl Bernstein 2019 West Virginia University

Effect Of Shear Bond Strength With Novel Apc™ Flash-Free Brackets And Different Bonding Protocol: An In Vitro Study, Carl Bernstein

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: In today’s time, there is an increasingly crowded field of competition vying over a small subset of the population. Now, more than ever it is imperative to compete with efficiency and esthetics. Each step for orthodontic bonding procedures increases the chance for error to occur. However, orthodontic bracket, etchant, sealant, and adhesive material has the ability to improve bond strength and final outcome for the patient and provider. The aim of this study was to determine effective bonding protocols for Advanced Clarity APC™ Flash-Free Brackets and to determine if adhesive remains on enamel or orthodontic bracket after …


Judged Facial Attractiveness Of Extraction And Non-Extraction Orthodontic Treatment In Repose And Smiling, Nicolette R. Chahin 2019 West Virginia University

Judged Facial Attractiveness Of Extraction And Non-Extraction Orthodontic Treatment In Repose And Smiling, Nicolette R. Chahin

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: More so than ever, the public is becoming exceedingly aware of esthetics, and will evaluate their treatment outcome based upon the improvement to their smile and overall enhancement of their facial appearance. There exists a debate in orthodontics, as to whether or not extractions harm the profile. The aim of this study was to determine if facial attractiveness is harmed in subjects having completed orthodontic treatment involving the extraction of four premolars both in repose and smiling when viewed in lateral profile. Another objective is to identify any impact upper incisor retraction has on facial attractiveness. …


Digital Scan To Enhance Patient Education, Dana Leann Tasche 2019 Eastern Washington University

Digital Scan To Enhance Patient Education, Dana Leann Tasche

EWU Masters Thesis Collection

Purpose: The purpose of this study was to evaluate if the use of a 3D intraoral scan as a visual aid improves a patient’s communication self-efficacy and risk-literacy concerning their periodontal disease status.

Methods: This study used a parallel experimental research design and collected quantitative data through a pre-test and two post-tests for both groups. The Ask, Understand, Remember Assessment (AURA) survey was used to collect quantitative data pertaining to patient communication self-efficacy and the Protection Motivation Survey (PMS) was used to evaluate each patient’s risk-literacy of their periodontal disease. The addition of four Likert-scale questions concerning experience with the …


Perceptions Of Dental Hygienists' Role On The Prenatal Care Team, Lisa Westhoff 2019 Eastern Washington University

Perceptions Of Dental Hygienists' Role On The Prenatal Care Team, Lisa Westhoff

EWU Masters Thesis Collection

Purpose: The purpose of this study was to examine dental hygienists’ perceptions of their role on the prenatal care team and perceptions of obstetricians towards the role of dental hygienists as part of the prenatal care team. Methods: Data was collected from an anonymous electronic Likert-style survey sent to obstetricians at Denver Health and Hospitality Authority (DHHA) and Colorado Dental Hygienists’ Association (CODHA) members. Statistical analysis included descriptive statistics to provide an overview of survey data from all three subscales: knowledge (subscale 1), scope (subscale 2), and perceptions (subscale 3) and the standard t-Test to determine differences between demographics (collaboration …


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