Dentistry Commons^™

Dental Practice Success Vol. 5 No. 3, American Dental Association, Publishing Division

Dental Practice Success

No abstract provided.

Nlrx1 Modulates Differentially Nlrp3 Inflammasome Activation And Nf-Κb Signaling During Fusobacterium Nucleatum Infection, Shu Chen Hung, Pei Rong Huang, Cassio Luiz Coutinho Almeida-Da-Silva, Kalina R. Atanasova, Ozlem Yilmaz, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

NOD-like receptors (NLRs) play a large role in regulation of host innate immunity, yet their role in periodontitis remains to be defined. NLRX1, a member of the NLR family that localizes to mitochondria, enhances mitochondrial ROS (mROS) generation. mROS can activate the NLRP3 inflammasome, yet the role of NLRX1 in NLRP3 inflammasome activation has not been examined. In this study, we revealed the mechanism by which NLRX1 positively regulates ATP-induced NLRP3 inflammasome activation through mROS in gingival epithelial cells (GECs). We found that depletion of NLRX1 by shRNA attenuated ATP-induced mROS generation and redistribution of the NLRP3 inflammasome adaptor protein, …

Knockdown Of Crispld2 In Zebrafish Identifies A Novel Network For Nonsyndromic Cleft Lip With Or Without Cleft Palate Candidate Genes, Brett T Chiquet, Qiuping Yuan, Eric C Swindell, Lorena Maili, Robert Plant, Jeffrey Dyke, Ryan Boyer, John F Teichgraeber, Matthew R Greives, John B Mulliken, Ariadne Letra, Susan H Blanton, Jacqueline T Hecht

Faculty, Staff and Student Publications

Orofacial development is a multifaceted process involving tightly regulated genetic signaling networks, that when perturbed, lead to orofacial abnormalities including cleft lip and/or cleft palate. We and others have shown an association between the cysteine-rich secretory protein LCCL domain containing 2 (CRISPLD2) gene and nonsyndromic cleft lip with or without cleft palate (NSCLP). Further, we demonstrated that knockdown of Crispld2 in zebrafish alters neural crest cell migration patterns resulting in abnormal jaw and palate development. In this study, we performed RNA profiling in zebrafish embryos and identified 249 differentially expressed genes following knockdown of Crispld2. In silico pathway analysis identified …

Using Enamel Matrix Derivative To Improve Treatment Efficacy In Periodontal Furcation Defects, Reza Masaeli, Kavosh Zandsalimi, Zahra Lotfi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose

Furcations are complicated periodontal defects. Untreated furcations lead to loss of the involved teeth and supporting tissues. It has been demonstrated that regenerative biomaterials are beneficial in reconstruction of the bone surrounding furcation‐affected teeth. These biomaterials range from bone grafts and nonresorbable/resorbable barrier membranes to biologics that are able to trigger inactive regenerative processes in periodontal tissues. Selection of appropriate material(s) to treat furcations is challenging. The aim of this article is to provide a comparative outlook on different biomaterials applicable in regeneration of furcations with a focus on enamel matrix derivative (EMD).

Methods

Scientific databases including PubMed/MEDLINE, ScienceDirect, …

Ada News - 09/17/2018, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

An Evalutaion Of The Physical Properties Of A New Atraumatic Restorative Treatment Material Containing Azadirachta Indica (Neem), Divya P. Kumari, Shahnawaz Khijmatgar, Avidyuti Chowdhury, Philippe B. Wilson, Edward Lynch, Martin Grootveld, Chitta Ranjan Chowdhury

Dental Medicine Faculty Research

BACKGROUND This in vitro experimental study investigated and compared the physical properties of three newly developed atraumatic restorative treatment materials. MATERIALS AND METHODS Atraumatic Restorative Treatment materials (ART) with three different compositions were prepared by varying the percentage of Azadirachta indica (Neem) extract within the materials. Micro-hardness, compressive strength, marginal adaptation to tooth structure of the atraumatic restorative treatment materials were assessed. Statistical Analysis Used- Data was analysed using SPSS version 20 statistical software. One-Way ANOVA, Tukey's Highly Significant Difference (HSD), Scheffe's tests were conducted to assess the level of significance of differences between mean values in post-hoc testings. P …

Vaccination Recommendations For Oral Health Professionals, Susan H. Davide, Christine Macarelli, Anty Lam

Publications and Research

Dental teams should familiarize themselves with vaccination recommendations to reduce the risk of infectious diseases and better educate patients about the importance of immunizations

Histone Deacetylase Inhibitors Prevent Persistent Hypersensitivity In An Orofacial Neuropathic Pain Model, Robert J. Danaher, Liping Zhang, Connor J. Donley, Nashwin A. Laungani, S. Elise Hui, Craig S. Miller, Karin N. Westlund

Oral Health Practice Faculty Publications

Chronic orofacial pain is a significant health problem requiring identification of regulating processes. Involvement of epigenetic modifications that is reported for hindlimb neuropathic pain experimental models, however, is less well studied in cranial nerve pain models. Three independent observations reported here are the (1) epigenetic profile in mouse trigeminal ganglia (TG) after trigeminal inflammatory compression (TIC) nerve injury mouse model determined by gene expression microarray, (2) H3K9 acetylation pattern in TG by immunohistochemistry, and (3) efficacy of histone deacetylase (HDAC) inhibitors to attenuate development of hypersensitivity. After TIC injury, ipsilateral whisker pad mechanical sensitization develops by day 3 and persists …

Ada News - 09/03/2018, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Correlation Between The Atlas Morphology And The Maxillo-Mandibular Divergence Pattern, Hafiz Taha Mahmood, Mubassar Fida

Section of Dental-Oral Maxillofacial Surgery

Objective: To evaluate the correlation between atlas morphology and maxillo-mandibular divergence.
Study design: Cross-sectional, analytic study.
Place and duration of study: Dental Clinics, The Aga Khan University Hospital, Karachi, Pakistan from February to August 2017.
Methodology: Pretreatment lateral cephalograms of 208 subjects, aged 18 to 25 years, were evaluated. The atlas parameters were categorized into atlas dorsum, anteroposterior and ventrum, and measured on View Pro-X software. Various maxillary (FPPP, SNPP and FHPP angles) and mandibular (SNGoGn, saddle, articulare, gonial, sum of posterior and Y-axis angles) parameters were used to evaluate the divergence pattern of the individuals. Mann-Whitney U-test was used …

Management Of Cervical Root Fracture Injury In A Patient With Epilepsy: Case Report With 5-Year Follow-Up, Elif Ataol, Gizem Erbaş Ünverdi, H. Cem Güngör

School of Dentistry Faculty Research and Publications

The difficulty in providing stability to the coronal segment makes cervical root fracture one of the most challenging dental traumatic injury. This type of injury is less frequent in children. However, due to their serious consequences and poor prognosis, tooth loss may occur. This report presents the management of a case of cervical root fracture in an 11-year-old patient with epilepsy. The stabilization of the root-fractured tooth with a splint failed due to the recurrent seizures the patient had. Coronal fragment was removed and vital root submergence was performed in order to support the alveolar growth. The natural tooth crown …

Effect Of Centric Interference On Canine Tooth Wear, Andrey Gaiduchik

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose: The aim of this study was to determine the long term effect of a centric interference on canine tooth wear (CTW) and on centric occlusion (CO) and maximal intercuspation (MIP) variance. Materials and Methods: Thirty subjects, 11 males and 19 females, were selected based on inclusion and exclusion criteria. Changes in enamel volume were studied between the end of orthodontic treatment (T2) and at least seven years post treatment (T4). All models were scanned using a high resolution desktop scanner, (OrthoInsight 3D Scanner™, MotionView LLC). T4 models were articulated using a Panadent® Articulator and evaluated for dental interferences and …

Estimating Root Volumes By Limited Segmentation: A Volumetric Analysis Of Cbct And Micro-Ct Data, Theresa C. Baldwin

Loma Linda University Electronic Theses, Dissertations & Projects

Introduction: The increased dimensional accuracy of images provided by cone beam computed tomography (CBCT) scans allows for more in-depth diagnosis and treatment planning. Expedient interpolation of segmented data that provides clinically acceptable results will encourage clinicians to frequently use CBCT images for clinical/radiographic evaluation. Some of these applications include, quantification of root resorption, determination of force required for specific tooth movements, and customized appliances. Purpose: The study had two purposes. The first was to compare the accuracy of digital tooth volumes acquired from CBCT to the gold standard, micro-computed tomography (micro-CT). The second was to determine the effect of axial …

Integrating Oral Health Into Social Marketing Campaigns: Program Development And Description For San Francisco Children’S Oral Health Strategic Plan, Carsen Bentley

Pacific Journal of Health

Integrating oral health into an existing San Francisco Department of Public Health (SFDPH) social marketing campaign was a specific goal of the San Francisco Children’s Oral Health Strategic Plan 2014-2017 with the purpose to more fully integrate oral health promotion into the City’s overall health promotion efforts. In the winter of 2015, utilizing a collaborative approach, oral health was successfully integrated in the Open Truth campaign, promoting decreased consumption of sugar sweetened beverages in order to improve health outcomes, including decreasing tooth decay.

Ada News - 08/20/2018, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Benefits Of Interprofessional Education Between Advanced Practice Nurse Practitioner And Dentistry Students, Oksana Prodan

DNP Qualifying Manuscripts

Background: Interprofessional Education (IPE) is mandated for accreditation in health professional schools. IPE between Advanced Practice Registered Nurse (APRN) and dentistry students have been developed to improve health oral systemic health outcomes and improve inter-professional practice competencies.

Method: Literature on APRN dental IPE was searched was searched via CINAHL Complete from 2007-2018, looking for scholarly journals, English language. The search was narrowed from 55 to three relevant, data-based studies.

Results: Review of literature produced one study demonstrating benefits of IPE for both APRN and dentistry students, one study only focused on benefits for APRN students, and another IPE article was …

Improving Pediatric Oral-Systemic Health Through Motivational Interviewing: An Interprofessional Training Intervention, Oksana Prodan

Doctor of Nursing Practice (DNP) Projects

Introduction: In response to the prevalence of early childhood carries (ECC) in the United States, recommendations were established for pediatric primary care providers to routinely incorporate oral-systemic health promotion services into clinical practice. An interprofessional education project was developed between Advanced Practice Registered Nurses (APRNs) and dentistry students in San Francisco to assist trainees in the effective delivery of oral systemic health promotion services. Improving health promotion communication skills was identified as an area of need for both sets of learners. Therefore, the IPE activity was designed to incorporate Motivational Interviewing (MI) into the training along with pediatric oral …

Ada News - 08/06/2018, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Green Tea Polyphenol Epigallocatechin-3-Gallate-Stearate Inhibits The Growth Of Streptococcus Mutans: A Promising New Approach In Caries Prevention, Amy Lynn Melok, Lee Lee, Siti Ayuni Mohamed Yussof, Tinchun Chu

Department of Biology Faculty Scholarship and Creative Works

Streptococcus mutans (S. mutans) is the main etiological bacteria present in the oral cavity that leads to dental caries. All of the S. mutans in the oral cavity form biofilms that adhere to the surfaces of teeth. Dental caries are infections facilitated by the development of biofilm. An esterified derivative of epigallocatechin-3-gallate (EGCG), epigallocatechin-3-gallate-stearate (EGCG-S), was used in this study to assess its ability to inhibit the growth and biofilm formation of S. mutans. The effect of EGCG-S on bacterial growth was evaluated with colony forming units (CFU) and log reduction; biofilm formation was qualitatively determined by Congo red assay, …

Trident - August 2018, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.