Dentistry Commons^™

N Y State Dent J March 2020

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Biodegradable Magnesium Bone Implants Coated With A Novel Bioceramic Nanocomposite, Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi, Lobat Tayebi, Daryoosh Vashaee

School of Dentistry Faculty Research and Publications

Magnesium (Mg) alloys are being investigated as a biodegradable metallic biomaterial because of their mechanical property profile, which is similar to the human bone. However, implants based on Mg alloys are corroded quickly in the body before the bone fracture is fully healed. Therefore, we aimed to reduce the corrosion rate of Mg using a double protective layer. We used a magnesium-aluminum-zinc alloy (AZ91) and treated its surface with micro-arc oxidation (MAO) technique to first form an intermediate layer. Next, a bioceramic nanocomposite composed of diopside, bredigite, and fluoridated hydroxyapatite (FHA) was coated on the surface of MAO treated AZ91 …

Celebrate! The Legacy Of Community Water Fluoridation Continues In Grand Rapids, James Wieland Dds

The Journal of the Michigan Dental Association

Michigan dentistry continues to tell the world about the great advance in public health that began in Grand Rapids 75 years ago. This article looks back at past commemorations, and a tribute to those who worked so hard to make a permanent monument to community water fluoridation.

Conducting A 10-Minute Search For Evidence To Aid In Clinical Decision-Making, Mark Maceachern Mlis

The Journal of the Michigan Dental Association

This article is a continuation of the Journal’s series on implementing EBD process into clinical practice. The abundance of scientific literature can make it difficult to find the best evidence to answer a clinical question. This article presents strategies for conducting a 10-minute search for the best evidence, including:

• Developing a PICO question to focus the search.
• Using free search engines such as PubMed, Google Scholar, TRIP, PubMed Clinical Queries, Medline-Plus.gov, Epistemonikos, and other online resources such as published ADA Clinical Practice Guidelines.
• Using keywords with search properties, such as Boolean Operators and filters, to discover specific types of articles, …

Community Water Fluoridation’S Legacy: Protect It Or Lose It, Johnny Johnson Dmd, Ms

The Journal of the Michigan Dental Association

This article presents advocacy strategies to promote and preserve community water fluoridation initiatives. The American Fluoridation Society, patterned after the British Fluoridation Society, brings dentists, health experts, and other allies and provides evidence-based resources to address a broad spectrum of assertion by fluoridation opponents.

Mmp-7 And Mmp-9 Are Overexpressed In The Synovial Tissue From Severe Temporomandibular Joint Dysfunction, Carla Loreto, Veronica Filetti, Luis Eduardo Almeida, Giusy Rita Maria La Rosa, Rosalia Leonardi, Cristina Grippaudo, Antonino Lo Giudice

School of Dentistry Faculty Research and Publications

Matrix metalloproteinases (MMPs) are tissue-enzymes that play a key role during the remodeling process, such as in inflammatory diseases. MMP-7 and MMP-9 have been shown to be implicated in extracellular matrix homeostasis and in joint disc remodeling. The objective of this study was to determine the relation of MMP-7 and MMP-9 expression with severe temporomandibular joint dysfunction, in particular with anterior disk displacement without reduction (ADDwoR), using an immunohistochemical approach. Therefore, twenty human temporomandibular synovia in the test group and ten in the control group were collected. The results showed there was a statistically significant difference (P<0.001) for morphometric and densitometric analysis of both detected MMPs in control and test groups. In conclusion, MMP-7 and MMP-9 were overexpressed in the synovial tissue of patients with ADDwoR.

Mechanistic Assessment Of Functionalized Mesoporous Silica-Mediated Insulin Fibrillation, Mohsen Akbarian, Lobat Tayebi, Soliman Mohammadi-Samani, Fatemeh Farjadian

School of Dentistry Faculty Research and Publications

Insulin, which is a small protein hormone consisting of 51 amino acids, rapidly fibrillates under stressogenic conditions. This biotechnological/ medical problematic reaction quickly accelerates in the presence of some particles, while there are several other particles that slow down the kinetic process. To address the unexplored demand of the particles that modulate protein fibrillation, we have synthesized two amino-based particles and a chitosan-coated mesoporous silica particle (MS-NH₂, MS-3NH₂, and MS-chitosan) to investigate insulin fibrillation. While these particles were fairly similar in size, they are differ in their net positive charge and surface hydrophobicity. To monitor the …

Relationship Between Oral Health And Clinical Osteoporosis Among Hospitalized Patients With And Without Diabetes, Kenneth Izoura, Gayle Allenback, Amber Champion, Civon Gewelber, Michael Neubauer

School of Medicine Faculty Research

Objective: Diabetes mellitus (DM) is associated with poor oral health and osteoporosis (OP). The aim of this study was to assess the relationship between OP, periodontal disease (PD), and other dental and health outcomes in a cohort of hospitalized patients with and without DM. Method: Using a cross-sectional study design, we enrolled consecutive hospitalized patients. We administered a questionnaire to gather demographic information, oral health history, smoking history, and history of OP. We inspected their dentition and reviewed their charts. Data were analyzed using t-tests, chi-square tests, and logistic regression models. Result: Out of 301 patients enrolled, 275 had PD, …

A Ferrofluidic Hydrophobic Deep Eutectic Solvent For The Extraction Of Doxycycline From Urine, Blood Plasma And Milk Samples Prior To Its Determination By High-Performance Liquid Chromatography-Ultraviolet, Ebrahim Alipanahpour Dil, Mehrorang Ghaedi, Arash Asafram, Lobat Tayebi, Fatemah Mehrabi

School of Dentistry Faculty Research and Publications

The ferrofluid phase was prepared according to mixing magnetic nanoparticle and the hydrophobic deep eutectic solvent as a green microextraction solvent. This new composite was applied for vortex-assisted dispersive liquid–liquid microextraction (VA-HDES-ferrofluid-DLLME) of doxycycline (DOC) residual extraction and determined through high-performance liquid chromatography-ultraviolet (HPLC-UV). The characterization of magnetic nanoparticle was investigated by XRD, TEM and FESEM. The dependency of DOC microextraction to main variables and their interaction and find optimum points were undertaken using response surface methodology with either central composite design (CCD). Thus, the optimum pH, ionic strength, ferrofluid volume and vortex time for DOC extraction are determined to …

The Role Of Glial Cell Derived Neurotrophic Factor In Head And Neck Cancer, Hongbin Cao, Qian He, Rie Von Eyben, Joshua Bloomstein, Dhanya K. Nambiar, Vignesh Viswanathan, Sonya Aggarwal, Shirley Kwok, Rachel Liang, Amanda J. Koong, James S. Lewis Jr., Christina Kong, Nan Xiao, Quynh-Thu Le

All Dugoni School of Dentistry Faculty Articles

Glial cell-derived neurotrophic factor (GDNF) is reported to promote the survival of neurons and salivary gland regeneration after radiation damage. This study investigated the effect of GDNF on cell migration, growth, and response to radiation in preclinical models of head and neck squamous cell carcinoma (HNSCC) and correlated GDNF expression to treatment outcomes in HNSCC patients. Our ultimate goal is to determine whether systemic administration of GDNF at high dose is safe for the management of hyposalivation or xerostomia in HNSCC patients. Three HPV-positive and three HPV-negative cell lines were examined for cell migration, growth, and clonogenic survival in vitro …

Trident - Spring 2020, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.

Ada News - 02/17/2020, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Spontaneous Condyle-Like Development After Total Resection Of Mandible Giant Osteochondroma: Case Report And A Follow-Up For Five Years, Marco Antonio De Oliveira Filho, Luis Eduardo Almeida, Andrea Doetzer, Allan Giovanini, Osvaldo Malafaia

School of Dentistry Faculty Research and Publications

Osteochondroma manifests as a benign tumor that occurs as an abnormal bony development. This tumor is commonly asymptomatic and presents an exophytic outgrowth on bone surfaces, near synovial joints, a condition that invariably induces evident facial deformities. Treatment for this type of tumor usually involves a surgical approach promoting a total or partial resection of the affected anatomical area associated to prosthetic reconstruction of the bone area extracted. We present a case report about a giant mandibular condyle osteochondroma in a 37-year-old female patient. Her treatment involved a total condylectomy without immediate condylar reconstruction, which would be performed in a …

Ada News - 02/03/2020, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Skeletal Stability Using Adjustable Versus Mini Plates Following Bilateral Sagittal Split Ramus Osteotomy (Bssro): A Randomized Clinical Trial, Moataz Bahaa, Omniya Abdelaziz, Gamal Moutamed, Ibrahim Shindy

Dentistry

Background and Objective: This study aimed at assessing the skeletal stability of adjustable miniplates in comparison to conventional miniplates following bilateral sagittal split ramus osteotomy (BSSRO)

Materials and Methods: Fourteen patients were divided into 2 equal groups. Patients in both groups underwent BSSRO and mandibular setback. In the study group, the bone segments at the osteotomy site were stabilized using the adjustable plates and four 2.0 mm monocortical screws. In the control group, bone segments at the osteotomy site were stabilized using conventional miniplates and four 2.0 mm monocortical screws. Each patient was assessed in terms SNB, mandibular plane angle …

Insight - February 2020, Dugoni School Of Dentistry

Insight

Whether you are involved in clinical research, biomedical research, the scholarship of teaching and learning, improvement of the health care system, or professional partnerships that advance the field, we aim to spotlight the work of people at the Dugoni School.

Dental Practice Success Special Issue: Marketing Principles (February 2020), American Dental Association, Publishing Division

Dental Practice Success

No abstract provided.

Role Of Dendritic Cell-Mediated Immune Response In Oral Homeostasis: A New Mechanism Of Osteonecrosis Of The Jaw, Ranya Elsayed, Zoya Kurago, Christopher W Cutler, Roger M Arce, Jennifer Gerber, Esteban Celis, Hussein Sultan, Mahmoud Elashiry, Mohamed Meghil, Christina Sun, Caroline M Auersvald, Mohamed E Awad, Rana Zeitoun, Riham Elsayed, Mohey Eldin M Elshikh, Carlos Isales, Mohammed E Elsalanty

Faculty, Staff and Student Publications

Dendritic cells are an important link between innate and adaptive immune response. The role of dendritic cells in bone homeostasis, however, is not understood. Osteoporosis medications that inhibit osteoclasts have been associated with osteonecrosis, a condition limited to the jawbone, thus called medication-related osteonecrosis of the jaw. We propose that disruption of the local immune response renders the oral microenvironment conducive to osteonecrosis. We tested whether zoledronate (Zol) treatment impaired dendritic cell (DC) functions and increased bacterial load in alveolar bone in vivo and whether DC inhibition alone predisposed the animals to osteonecrosis. We also analyzed the role of Zol …

Recent Advances In Porphyrin-Based Nanocomposites For Effective Targeted Imaging And Therapy, Navid Rabiee, Mohammad Tavakkoli Yaraki, Soha Mokhtari Garakani, Shima Mokhtari Garakani, Sepideh Ahmadi, Aseman Lajevardi, Mojtaba Bagherzadeh, Mohammad Rabiee, Lobat Tayebi, Mohammadreza Tahriri, Michael R. Hamblin

School of Dentistry Faculty Research and Publications

Porphyrins are organic compounds that continue to attract much theoretical interest, and have been called the “pigments of life”. They have a wide role in photodynamic and sonodynamic therapy, along with uses in magnetic resonance, fluorescence and photoacoustic imaging. There is a vast range of porphyrins that have been isolated or designed, but few of them have real clinical applications. Due to the hydrophobic properties of porphyrins, and their tendency to aggregate by stacking of the planar molecules they are difficult to work with in aqueous media. Therefore encapsulating them in nanoparticles (NPs) or attachment to various delivery vehicles have …

Comparison Of Shaping Ability Of Different Single-File Systems Using Microcomputed Tomography, Shehabeldin Mohamed Saber Prof.Dr.

Dentistry

Objectives To evaluate the shaping ability of four different single-file systems using micro-computed tomography (micro-CT). Materials and Methods Eighty mesiobuccal and mesiolingual canals of permanent mandibular molars were randomly assigned to four groups according to the file used; WaveOne Gold, RECIPROC Blue, HyFlex EDM, and One Shape (n = 20). The samples were scanned using micro-CT for the preinstrumentation record; then the canals were instrumented and scanned for the postinstrumentation records. Statistical Analysis The data were then analyzed statistically using one-way analysis of variance (ANOVA) with the level of significance set at α = 0.05. Results The results of canal …