Conditioned Medium Of Lipopolysaccharide-Treated Embryonic Stem Cell-Derived Mesenchymal Stem Cells Modulates In Vitro Secretion Of Inflammatory Cytokines,
2020
Chulalongkorn University
Conditioned Medium Of Lipopolysaccharide-Treated Embryonic Stem Cell-Derived Mesenchymal Stem Cells Modulates In Vitro Secretion Of Inflammatory Cytokines, Faezeh Maghsood, Behrooz Johari, Nastaran Mohammadi Ghahhari, Mohammad Moradi, Mehdi Kadivar
The Thai Journal of Pharmaceutical Sciences
Background: The immunomodulatory properties of mesenchymal stem cells (MSCs) secretome have been considered by many investigators, and several preconditioning strategies such as pharmaceutical preconditioning have shown to strengthen the immunomodulatory.
Training Needs Of Thai Community Pharmacists For Primary Care Pharmacy: Qualitative Exploration,
2020
Chulalongkorn University
Training Needs Of Thai Community Pharmacists For Primary Care Pharmacy: Qualitative Exploration, Surangkana Puengrung, Suntaree Watcharadamrongkun, Win Winit-Watjana
The Thai Journal of Pharmaceutical Sciences
Introduction: Primary care pharmacy is crucial for community pharmacists and requires special training for some services. Objective: This study aims to explore current training needs of community pharmacists for primary care pharmacy using the Organizati.
The Effect And Cost Of Smoking Cessation Services Provided By Community Pharmacists In Thailand: A Descriptive Study Approach,
2020
Chulalongkorn University
The Effect And Cost Of Smoking Cessation Services Provided By Community Pharmacists In Thailand: A Descriptive Study Approach, Sunee Lertsinudom, Nadthatida Hansuri, Ampornpan Theeranut, Piyameth Dilokthornsakul
The Thai Journal of Pharmaceutical Sciences
Introduction: The effect and cost of smoking cessation provided by pharmacists was varied and important for policy decision making. Aims: The aim of the study was to estimate the effect and cost of smoking cessation provided by community pharmacists in T.
Association Of N-Acetyltransferase 2 (Nat2) Polymorphisms And Elevated Liver Enzymes Of Myanmar Tuberculosis Patients In Thailand,
2020
Chulalongkorn University
Association Of N-Acetyltransferase 2 (Nat2) Polymorphisms And Elevated Liver Enzymes Of Myanmar Tuberculosis Patients In Thailand, Khin Sandi Thaw, Chanchira Choppradit, Pornpimol Kijsanayotin, Ratchanee Rodsiri
The Thai Journal of Pharmaceutical Sciences
Isoniazid (INH) and its toxic metabolites are the major cause of anti-tuberculosis (TB) druginduced liver injury (AT-DILI). N-acetyltransferase 2 (NAT2) is involved in many metabolic pathways of INH. Previous studies demonstrated the association of NAT2 .
Tumor Suppressive Effect Of Artemisia Annua Extract In 7, 12-Dimethylbenz[A]Anthracene-Induced Breast Cancer In Wistar Rats,
2020
Chulalongkorn University
Tumor Suppressive Effect Of Artemisia Annua Extract In 7, 12-Dimethylbenz[A]Anthracene-Induced Breast Cancer In Wistar Rats, Hemmat M.M. Faheem, Sameh M. M. El Nabtity, Mohamed A. M. Nassan
The Thai Journal of Pharmaceutical Sciences
Objective: This study aimed to detect the genetic and immunohistochemical effects of the extract of Artemisia annua, a popular medicinal herb in a chemical model of breast cancer. Materials and Methods: Breast cancer was induced in female rats by 7, 12-d.
Increasing The Solubility Of Levodopa And Carbidopa Using Ionization Approach,
2020
Chulalongkorn University
Increasing The Solubility Of Levodopa And Carbidopa Using Ionization Approach, Kitisak Krisai, Dusadee Charnvanich, Wanchai Chongcharoen
The Thai Journal of Pharmaceutical Sciences
The aim of this study is to increase the solubility of levodopa (LD) and carbidopa (CD) to improve loading quantity of both drugs for oral pullulan thin film preparation. Solubilization technique through ionization was employed to measure the solubility .
Comparative Evaluation Of The Effects Of N-Hexane, Chloroform, And Methanol Fractions Of Ricinus Communis In Carbon Tetrachloride-Induced Hepatotoxic Rats,
2020
Chulalongkorn University
Comparative Evaluation Of The Effects Of N-Hexane, Chloroform, And Methanol Fractions Of Ricinus Communis In Carbon Tetrachloride-Induced Hepatotoxic Rats, Matthew Obaineh Ojezele
The Thai Journal of Pharmaceutical Sciences
Background: Ricinus communis is widely used among the Nigerian populace in ethnomedicine for the treatment of liver diseases. Aim of the Study: A comparative study was carried out to evaluate the hepatoprotective activity of its n-hexane, chloroform, and.
Pharmacokinetics Of 8 Mg Galantamine Hydrobromide Prolonged-Release Capsules Under Fed And Fasting Conditions,
2020
Chulalongkorn University
Pharmacokinetics Of 8 Mg Galantamine Hydrobromide Prolonged-Release Capsules Under Fed And Fasting Conditions, Chuleegone Sornsuvit, Narawadee Niamhun, Parichat Salee, Darunee Hongwiset, Songwut Yotsawimonwat, Chockchai Wongsinsup
The Thai Journal of Pharmaceutical Sciences
Objective: The objective of the study was to determine the pharmacokinetics of 8 mg galantamine prolonged-release capsules under fed and fasting conditions. Materials and Methods: A randomized, open-label, single-dose, two-treatment, two-period, two-sequ.
Development And Evaluation Of Gastroretentive Formulations For Moxifloxacin Hydrochloride,
2020
Chulalongkorn University
Development And Evaluation Of Gastroretentive Formulations For Moxifloxacin Hydrochloride, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
The Thai Journal of Pharmaceutical Sciences
Purpose: The objective of the current study is to develop gastroretentive formulation for moxifloxacin HCl (hydrochloride) using various drug release modifiers and performing in vitro and in vivo evaluations. Moxifloxacin is a novel synthetic compound ha.
Anticonvulsant Activity Of Fumaria Schleicheri Dry Extract And Sodium Valproate: Role Of Neurotrophin And Cytokine Pathways,
2020
Chulalongkorn University
Anticonvulsant Activity Of Fumaria Schleicheri Dry Extract And Sodium Valproate: Role Of Neurotrophin And Cytokine Pathways, Vadim Tsyvunin, Sergiy Shtrygol, Tetiana Gorbatch, Diana Shtrygol
The Thai Journal of Pharmaceutical Sciences
Introduction: Cytokine and neurotrophin pathways can be potential targets for principally new anticonvulsant drugs which in perspective will be probably able to solve the problem of pharmacological resistance for people sick with epilepsy and to avoid po.
Synthesis, Evaluation, And In Silico Studies Of 2-Mercapto-5-Substituted Styryl-1,3,4-Oxadiazoles As Potential Cytotoxic Agents,
2020
Chulalongkorn University
Synthesis, Evaluation, And In Silico Studies Of 2-Mercapto-5-Substituted Styryl-1,3,4-Oxadiazoles As Potential Cytotoxic Agents, Anitha Kumari Vinjavarapu, Shaheen Begum, Bharathi Koganti
The Thai Journal of Pharmaceutical Sciences
Objective: The objective of the present study is to design, synthesize and evaluate 2-mercapto-5-styryl-1,3,4-oxadiazoles with an aim of developing potential cytotoxic agents and to carryout in silico studies to understand the possible interactions with .
Optimizing The Method For Quantification Of Apigenin And Quercetin In The Thai Herbal Sattakavata Formula By Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometer,
2020
Chulalongkorn University
Optimizing The Method For Quantification Of Apigenin And Quercetin In The Thai Herbal Sattakavata Formula By Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometer, Khuannara Narajeenrone, Jantanee Wattanarangsan, Kajee Pilakasiri, Pravit Akarasereenont, Suksalin Booranasubkajorn
The Thai Journal of Pharmaceutical Sciences
Introduction: Sattakavata formula (SVF) is a Thai traditional medicine from Ayurved Siriraj for a relief of joint pain. It comprises six ingredients, namely, Andrographis paniculata (Burm. F.) Wall. ex Nees (AP), Cinnamomum sp. (CN), Morus alba Linn. (MA.
Beta-Blocker And Its Neuropsychiatric Effects,
2020
Chulalongkorn University
Beta-Blocker And Its Neuropsychiatric Effects, Ploylarp Lertvipapath, Wikrom Warunyuwong
The Thai Journal of Pharmaceutical Sciences
Norepinephrine from locus coeruleus plays roles in memory processes and behavioral controls. Locus coeruleus change is found in the primary neurodegenerative disease. The disruption of this central adrenergic pathway could contribute to neuropsychiatric .
Ocimum Gratissimum Linn. (Lamiaceae) Protects Wistar Rats Against Inflammation And Oxidative Stress In Trinitrobenzene Sulfonic Acid-Induced Colitis,
2020
Chulalongkorn University
Ocimum Gratissimum Linn. (Lamiaceae) Protects Wistar Rats Against Inflammation And Oxidative Stress In Trinitrobenzene Sulfonic Acid-Induced Colitis, O. O. Abiodun, N. Nwadike, F. N. Ogunleye, A. S. Sosanya
The Thai Journal of Pharmaceutical Sciences
Background and Aim: The activity of methanol extract of leaf of Ocimum gratissimum a plant with anti-inflammatory, antioxidant, and anti-ulcerogenic activities in a rat model of colitis was evaluated. Experimental Procedures: Colitis was induced in 30 of.
Monodora Myristica Seed Extracts Ameliorate Crude Oil Contaminated Diet-Induced Cardiotoxicity In Rats,
2020
Chulalongkorn University
Monodora Myristica Seed Extracts Ameliorate Crude Oil Contaminated Diet-Induced Cardiotoxicity In Rats, G. T. Esiekpe, B. O. George, O. C. Orororo, A. A. Akpede, G. E. Okevwe, E. Onotugoma, J. Oguntola
The Thai Journal of Pharmaceutical Sciences
Aim: This study investigated the ameliorative effects of Monodora myristica seed extracts in serum and heart of rats fed crude petroleum oil-polluted diet (CPOPD). ). Materials and Methods: Thirty adult Wistar rats (180 ± 5 g) were used for the study. T..
Development Of Immunofet Biosensor For Detection Of 3-Nitrotyrosine,
2020
Chulalongkorn University
Development Of Immunofet Biosensor For Detection Of 3-Nitrotyrosine, Khine Kyi Han, Supachoke Mangmool, Korbtham Sathirakul, Kosum Chansiri, Wutthinan Jeamsaksiri, Prapimpun Wongchitrat, Montri Yasawong
The Thai Journal of Pharmaceutical Sciences
3-Nitrotyrosine (3-NT) is one of the important biomarkers for the detection of excess of oxidative and nitrosative stress in the body, and derived from peroxynitrite-induced nitration of free and protein-bound at tyrosine residues. It was increased with .
A Comparison Of Model Fitting Using Different Runs In Box–Behnken Design For Alginate Film Formulation,
2020
Chulalongkorn University
A Comparison Of Model Fitting Using Different Runs In Box–Behnken Design For Alginate Film Formulation, Nichayarach Invichian N/A, Warangkana Warisnoicharoen
The Thai Journal of Pharmaceutical Sciences
Introduction: Box–Behnken design (BBD) is a response surface method used for experimental design in several applications such as pharmaceutical and food. BBD experiment can be run using different central points (CPs) for analyzing optimal model fitting...
Protective Effect Of Croton Zambesicus Leaf Extract Against Carbon Tetrachlorideinduced Cardiac Toxicity In Rats,
2020
Chulalongkorn University
Protective Effect Of Croton Zambesicus Leaf Extract Against Carbon Tetrachlorideinduced Cardiac Toxicity In Rats, Rashidat Oluwafunke Ayanniyi, Hidayah Ayodeji Olumoh-Abdul, Fatimoh Idowu Ojuade, Nnaemeka Asogwa
The Thai Journal of Pharmaceutical Sciences
Background: The leaves of Croton zambesicus (CZ) Muell Arg. (Euphorbiaceae) are used as a spice for food and in traditional medicine for the management of several disease conditions, including hypertension and diabetes. The study was carried out to deter.
Cytotoxicity And Antiplasmodial Activity Of Alkaloid Extracts Prepared From Eight African Medicinal Plants Used In Nigeria,
2020
Chulalongkorn University
Cytotoxicity And Antiplasmodial Activity Of Alkaloid Extracts Prepared From Eight African Medicinal Plants Used In Nigeria, U. E. Uzuegbu, O. A. Opajobi, J. E. Utalor, C. O. Elu, I. Onyesom
The Thai Journal of Pharmaceutical Sciences
Objectives: Malaria morbidity and mortality rates are worsening, despite the dedicated commitment to eradicate the infestation, principally because of failing chemotherapy, the mainstay of treatment, and lack of registered vaccine. Therefore, the search .
Cell Lysis Methods And Coenzyme Q10 Production Of Methylobacterium Strains,
2020
Chulalongkorn University
Cell Lysis Methods And Coenzyme Q10 Production Of Methylobacterium Strains, Nattida Mingrapoch, Somboon Tanasupawat, Dusadee Charnvanich
The Thai Journal of Pharmaceutical Sciences
Objective: This research aimed to investigate the effect of cell lysis methods on a quantity of coenzyme Q10 (CoQ10) produced by Methylobacterium strains. Methods: Methylobacterium organophilum NBRC 15689T and Methylobacterium strain LRY1-08 were used to.
