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A New Era In Biological Monitoring Of Toluene Biomarker In Urine Through Dansylation Of O-Cresol And Lc-Ms/Ms Analysis, Sébastien Gagné, Eric Langlois 2024 Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST)

A New Era In Biological Monitoring Of Toluene Biomarker In Urine Through Dansylation Of O-Cresol And Lc-Ms/Ms Analysis, Sébastien Gagné, Eric Langlois

Communications orales

O-cresol in urine after hydrolysis is an exposure biomarker for toluene. This biomarker is volatile and routinely analyzed by gas chromatography−flame ionization detection (GC-FID) or gas chromatography−mass spectrometry (GC-MS). However, given the stringent sample preparation procedures required to ensure reliable GC-MS results, high-throughput sample analysis is not possible. In addition, the GC-FID detection limit for o-cresol in urine after hydrolysis is around 0.5 mg/L, while the ACGIH BEI is 0.3 mg/g cr (0.09 mg/L, if creatinine is 0.3 g/L; and 0.9 mg/L, if creatinine is 3 g/L). In other words, overexposure of some workers will not be detected by GC-FID …


Evaluation Of The Water Quality And Distribution Of Heavy Metals In The Gomti River Flowing Through The Urban Region Of Lucknow, India, Neha Gondial, Sandhya Bharti 2024 Fish Physiology and Ecotoxicology Laboratory, Department of Zoology, Babasaheb Bhimrao Ambedkar University, Lucknow 226025, India

Evaluation Of The Water Quality And Distribution Of Heavy Metals In The Gomti River Flowing Through The Urban Region Of Lucknow, India, Neha Gondial, Sandhya Bharti

Makara Journal of Science

The physicochemical properties and heavy metals contents of the Gomti River water (GRW) samples collected from five selected sites covering a stretch of ~31 km in Lucknow, Uttar Pradesh, India were ascertained. The sites were Ghaila Pul, Mehndi Ghat, Shaheed Smarak, Kukrail Junction, and Bande Dam, represented as S1, S2, S3, S4, and S5, respectively, following from upstream to downstream. S1 was considered as a reference site. The values of pH, temperature, total dissolved solids (TDS), electrical conductivity (EC), turbidity, dissolved oxygen (DO), biochemical oxygen demand (BOD), total hardness (TH), total chloride (TC), total alkalinity (TA), total acidity (TAC), total …


Influences Of Quality Of Maternal Care And Environmental Enrichment On Associative Memory Function In Rats With Early Life Lead Exposure, Jay S. Schneider, Courtney Williams, Shamaila Zafar, Jaehyun Joo, Blanca E Himes 2024 Thomas Jefferson University

Influences Of Quality Of Maternal Care And Environmental Enrichment On Associative Memory Function In Rats With Early Life Lead Exposure, Jay S. Schneider, Courtney Williams, Shamaila Zafar, Jaehyun Joo, Blanca E Himes

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

INTRODUCTION: Children in low socioeconomic status (SES) communities are at higher risk of exposure to lead (Pb) and potentially more severe adverse outcomes from Pb exposures. While the factors encompassing SES are complex, low SES households often have less enriching home environments and parent-child interactions. This study investigated the extent to which environmental/behavioral factors (quality of maternal care and richness of the postnatal environment) may modify adverse effects from Pb exposure.

METHODS: Long-Evans female rats were randomly assigned to Control (no Pb), Early Postnatal (EPN: birth through weaning), or Perinatal (PERI: 14 days pre-mating through weaning) Pb exposure groups. From …


Emerging Contaminants In Extreme Environments: Microplastics Monitoring In Karst Springs Of Montenegro, Marko Nikolic, Djuradj Milosevic, Ana Manovic, Vladimir Pesic, Melita Mustafic, Dragana Asceric, Milica Nikolic, Dimitrija Savic-Zdravkovic 2024 University of Nis, Serbia

Emerging Contaminants In Extreme Environments: Microplastics Monitoring In Karst Springs Of Montenegro, Marko Nikolic, Djuradj Milosevic, Ana Manovic, Vladimir Pesic, Melita Mustafic, Dragana Asceric, Milica Nikolic, Dimitrija Savic-Zdravkovic

FRONTIERS UNBOUND: Exploring Extreme Environments

No abstract provided.


Corrigendum To "Chemical Constituents From A Marine Medicinal Brown Alga-Derived Xylaria Acuta Sc1019," Journal Of Food And Drug Analysis: Vol. 32 : Iss. 2 , Article 3., 2024 Taiwan Food and Drug Administration

Corrigendum To "Chemical Constituents From A Marine Medicinal Brown Alga-Derived Xylaria Acuta Sc1019," Journal Of Food And Drug Analysis: Vol. 32 : Iss. 2 , Article 3.

Journal of Food and Drug Analysis

No abstract provided.


Corrigendum To “Composition Decipherment Of Ficus Pumila Var. Awkeotsang And Its Potential On Covid-19 Symptom Amelioration And In Silico Prediction Of Sars-Cov-2 Interference.”, 2024 Taiwan Food and Drug Administration

Corrigendum To “Composition Decipherment Of Ficus Pumila Var. Awkeotsang And Its Potential On Covid-19 Symptom Amelioration And In Silico Prediction Of Sars-Cov-2 Interference.”

Journal of Food and Drug Analysis

No abstract provided.


Characterization Of Carbon Dots From Fructus Gardeniae (Zhi-Zi) And Gardenia Charcoal (Black Zhi-Zi) Via Microwave-Assisted Extraction, Hung-Wen Tsai, Nelly Fitri Tampubolon, Tsunghsueh Wu, Mei-Yao Wu, Yang-Wei Lin 2024 Department of Chemistry, National Changhua University of Education, 1 Jin-De Road, Changhua City, 50007, Taiwan

Characterization Of Carbon Dots From Fructus Gardeniae (Zhi-Zi) And Gardenia Charcoal (Black Zhi-Zi) Via Microwave-Assisted Extraction, Hung-Wen Tsai, Nelly Fitri Tampubolon, Tsunghsueh Wu, Mei-Yao Wu, Yang-Wei Lin

Journal of Food and Drug Analysis

We employed a straightforward microwave-assisted extraction technique to investigate the presence of carbon dots (CDs) in Chinese herbal extracts derived from fructus gardeniae and gardenia charcoal, designated as CDs-1 and CDs-2, respectively. The found CDs exhibited unique photoluminescence with quantum yields of 0.95% for CDs-1 and 1.81% for CDs-2, indicating significant potential for bioimaging applications. Both CD types maintain approximately 80% of their fluorescence intensity after 120 minutes of continuous 365 nm UV exposure, underscoring their stability and suitability for prolonged biological studies. Moreover, antioxidant activity tests showed that CDs-2 have a higher scavenging capacity, with an SC-50 value of …


Optimization, Physicochemical Stability And In Vivo Study Of Alginate-Chitosan Composites As Nanocarriers For Low Molecular Weight Angiotensin I-Converting Enzyme (Ace)-Inhibitory Peptide, Shehu Muhammad Auwal, Siti Balqis Muhammad Ghanisma, Nazamid Saari 2024 Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, UPM, 43400 Serdang, Selangor, Malaysia

Optimization, Physicochemical Stability And In Vivo Study Of Alginate-Chitosan Composites As Nanocarriers For Low Molecular Weight Angiotensin I-Converting Enzyme (Ace)-Inhibitory Peptide, Shehu Muhammad Auwal, Siti Balqis Muhammad Ghanisma, Nazamid Saari

Journal of Food and Drug Analysis

Chitosan and alginate, are non-toxic and biodegradable polymers used to enhance the stability of biotherapeutics by loading them into nanocarriers. In this study, the stone fish-derived low molecular weight peptide (Ala-Leu-Gly-Pro-Gln-Phe-Tyr), exhibited an in vitro ACE-inhibitory activity of 94.43 ± 2.05% and an IC50 of 0.012 ± 0.001 mM. The peptide was encapsulated via ionic gelation with alginate followed by polyelectrolyte complexation with chitosan. The resulting ACE-inhibitory peptide-loaded alginate-chitosan nanoparticles (ACE-I-ALG-CS NPs) were optimized to achieve small particle size (212.60 nm) and high encapsulation efficiency (EE, 74.48%). This was based on an optimum chitosan concentration (0.420%w/v), homogenization speed (6000 …


Sensitive Electrochemical Sensor Of Levofloxacin Using Boron-Doped Diamond (Bdd) Electrode Modified With Ti3c2tx (Mxene) Material, Prastika Krisma Jiwanti, Indah Harindy Putri, Grandprix T.M. Kadja, Yasuaki Einaga, Laurencia Gabrielle Sutanto, Siti Wafiroh, Dewi Kartika Azizah Sukardi, Anis Puspita Sari, Tahta Amrillah, Ilma Amalina, Qonita Kurnia Anjani, Wan Jeffrey Basirun 2024 Nanotechnology Engineering, Faculty of Advanced Technology and Multidiscipline, University of Airlangga, Surabaya 60115, Indonesia

Sensitive Electrochemical Sensor Of Levofloxacin Using Boron-Doped Diamond (Bdd) Electrode Modified With Ti3c2tx (Mxene) Material, Prastika Krisma Jiwanti, Indah Harindy Putri, Grandprix T.M. Kadja, Yasuaki Einaga, Laurencia Gabrielle Sutanto, Siti Wafiroh, Dewi Kartika Azizah Sukardi, Anis Puspita Sari, Tahta Amrillah, Ilma Amalina, Qonita Kurnia Anjani, Wan Jeffrey Basirun

Journal of Food and Drug Analysis

Overuse of levofloxacin (LEV) is often associated with bacterial resistance and serious health problems, underscoring the need for reliable sensing and monitoring of LEV molecules. Therefore, this study aimed to investigate LEV using boron-doped diamond (BDD) and boron-doped diamond modified with MXene (Ti3C2TX) (BDD-MXene) electrode. The successful deposition of MXene on the BDD surface was confirmed using scanning electron microscope (SEM). Cyclic voltammetry (CV) and square wave voltammetry (SWV) methods were also applied to evaluate the electrochemical behavior. The results showed that both electrodes had a linear response in the range of 30-100 µM. …


Production And Characterization Of Encapsulated Thymoquinone Loaded Bacterial Cellulose/Chitosan Composite Nano Film And Investigation Of Its In Vitro Antibacterial Activity, Aytul Bayraktar, Tunc Tuba 2024 Department of Chemical/Bioengineering, Suleyman Demirel University, Isparta 32260, Turkey

Production And Characterization Of Encapsulated Thymoquinone Loaded Bacterial Cellulose/Chitosan Composite Nano Film And Investigation Of Its In Vitro Antibacterial Activity, Aytul Bayraktar, Tunc Tuba

Journal of Food and Drug Analysis

In this study, nanostructured thin films were produced from thymoquinone (TQ)-loaded composites encapsulated with different ratios of bacterial nanocellulose (BNC) to chitosan (CS). The study aimed to investigate their characterization, antibacterial effects, and potential as drug film coating materials. Chemical features and morphological characteristics were determined, and release tests and antibacterial assays were conducted on the thin film layers. As a result, BNC/CS-thymoquinone composite films obtained at different ratios were found to exhibit the highest antibacterial effect, particularly films with a 70% BNC/CS to 30% thymoquinone ratio, against Salmonella typhimurium bacteria.


Enhancing Mango Shelf Life Through Natural Preservation: Investigating The Efficacy Of Polysaccharide Edible Coating And Leaf Extracts, Binh Minh Nguyen Dac, Khoa Hai Le, Van Anh Phan Thi, Van Minh Dao, Trung Dinh Do, Phuong Nguyen-Tri, S. Woong Chang, D. Duc Nguyen, Duong Duc La 2024 Institute of Regional Research and Development, Ministry of Science and Technology, Hanoi, Vietnam

Enhancing Mango Shelf Life Through Natural Preservation: Investigating The Efficacy Of Polysaccharide Edible Coating And Leaf Extracts, Binh Minh Nguyen Dac, Khoa Hai Le, Van Anh Phan Thi, Van Minh Dao, Trung Dinh Do, Phuong Nguyen-Tri, S. Woong Chang, D. Duc Nguyen, Duong Duc La

Journal of Food and Drug Analysis

A sustainable solution to prevent the waste of fruits and vegetables from spoilage is the use of edible coatings or films. This research project aimed to create a fresh coating recipe that could effectively extend the shelf life of mangoes. The coating was composed of chitosan, glycerol, and gum Arabic mixed with the extract obtained from the extraction of Cleistocalyx operculatus plant. The prepared exact has a total polyphenol content of 17% and showed potent free radical scavenging abilities in a dose-dependent manner. The chitosan/gum Arabic/Glycerol/extract edible coatings were analyzed using SEM and FTIR spectroscopy, revealing a smooth and uniform …


Unlocking Early Detection Of Alzheimer's Disease: The Emerging Role Of Nanomaterial-Based Optical Sensors, Chun-Hsien Chen, Hsin-Hua Liang, Chun-Chi Wang, Yi-Ting Yang, Yi-Hui Lin, Yen-Ling Chen 2024 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.

Unlocking Early Detection Of Alzheimer's Disease: The Emerging Role Of Nanomaterial-Based Optical Sensors, Chun-Hsien Chen, Hsin-Hua Liang, Chun-Chi Wang, Yi-Ting Yang, Yi-Hui Lin, Yen-Ling Chen

Journal of Food and Drug Analysis

Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disorder that affects millions of individuals worldwide. Researchers have conducted numerous studies to find accurate biomarkers for early AD diagnosis and develop more effective treatments. The main pathological hallmarks of AD are amyloid beta and Tau proteins. Other biomarkers, such as DNA, RNA, and proteins, can also be helpful in early AD diagnosis. To diagnose and treat AD promptly, it is essential to accurately measure the concentration of biomarkers in the cerebrospinal fluid or blood. However, due to the low concentrations of these biomarkers in the body, highly sensitive analytical techniques …


Harnessing Gold Nanomaterials For Advanced Multicolor Colorimetric Biosensors In Food Hazards Detection, Longyingzi Xie, Chenxi Guo, Lu Yang, Yue He 2024 Key Laboratory of Quality and Safety Control of Citrus Fruits, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400712, P.R. China

Harnessing Gold Nanomaterials For Advanced Multicolor Colorimetric Biosensors In Food Hazards Detection, Longyingzi Xie, Chenxi Guo, Lu Yang, Yue He

Journal of Food and Drug Analysis

Hazards such as pathogenic bacteria, mycotoxins, pesticides, antibiotics, heavy metal ions, etc., cause serious food safety problems worldwide due to their toxicity and frequent contamination. Rapid screening is an effective way for food safety control, which highly relies on the development of sensitive, specific, and convenient detection methods. The multicolor colorimetric biosensors based on gold nanomaterials have evolved into advanced tools for detecting various hazards in food, with intuitive readout. The excellent localized surface plasmon resonance (LSPR) properties of gold nanomaterials enable them to exhibit bright colors when used as chromophores. In addition, the small changes in the morphology of …


Functional Gold Nanoparticles For Analysis And Delivery Of Nucleic Acids, Po-Tsang Huang, Yen-Ling Chen, Yi-Hui Lin, Chun-Chi Wang, Huan-Tsung Chang 2024 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.

Functional Gold Nanoparticles For Analysis And Delivery Of Nucleic Acids, Po-Tsang Huang, Yen-Ling Chen, Yi-Hui Lin, Chun-Chi Wang, Huan-Tsung Chang

Journal of Food and Drug Analysis

Gold nanoparticles (AuNPs) have become the rising stars in the field of nanotechnology and made a revolution in exploiting the profundity of genomics due to their distinguished properties such as stability, ease in preparation and conjugation, biocompatibility, and unique optical properties. These characteristics have greatly expanded their applications such as sensitive and selective quantitation of nucleic acids and as effective carriers for specifically delivering various important molecules/biomolecules to various targets, which are the cornerstone in treating genetic disorders. This review comprehensively discusses the most recent progress in utilization of AuNPs in quantitation and delivery of nucleic acids. The future prospects …


Preface, Chih-Ching Huang, Yang-Wei Lin, Amit Nain 2024 Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, 20224, Taiwan

Preface, Chih-Ching Huang, Yang-Wei Lin, Amit Nain

Journal of Food and Drug Analysis

No abstract provided.


Growth And Mobility Of Physella Acuta Under Individual And Combined Acetaminophen And Salinity Exposure, Rhea Wilder, Jason Doll, Daniel Elias 2024 North Carolina Wesleyan University

Growth And Mobility Of Physella Acuta Under Individual And Combined Acetaminophen And Salinity Exposure, Rhea Wilder, Jason Doll, Daniel Elias

Journal of the South Carolina Academy of Science

Global climate change, driven by rapid population growth and anthropogenic activities, presents an urgent challenge to aquatic ecosystems. Salinity intrusion threatens water quality and availability for human and wildlife populations. At the same time, due to the demand for pharmaceuticals, these pollutants are increasingly detected in freshwater environments, with acetaminophen being one of the most prevalent. This research analyzed the individual and combined effects of salinity (2.5 g/L) and acetaminophen (488 μg/L) on Physella acuta. Overall, we observed reduced snail movement under elevated salinity and no effects on growth or movement with acetaminophen alone or in combination with salinity. …


Biogeochemical Consequences Of A Changing Cryosphere: Assessing Spatial And Temporal Variability In Arctic And Sub-Arctic Lake Chemistry, Ansley Grider 2024 University of Maine

Biogeochemical Consequences Of A Changing Cryosphere: Assessing Spatial And Temporal Variability In Arctic And Sub-Arctic Lake Chemistry, Ansley Grider

Electronic Theses and Dissertations

The fate of heavy metals and nutrients melting out of the cryosphere into aquatic systems is not well understood. In chapter 2 of this thesis, we addressed this knowledge gap by measuring heavy metals and nutrients in the water and sediment of four glacially-fed (GF) and four snow and groundwater-fed (SF) lakes near Kangerlussuaq, West Greenland during the summer of 2023. GF lakes had 86% higher water concentrations of nutrients -- total phosphorus (TP), NO3-, and NH4+ -- and 137% higher concentrations of some metals -- Cd, Pb, Cr, Co, Ni, Al, Fe, Cu, Zn …


Assessment Of Tce And Chiral Pcb Dechlorination Rate, Congener Diversity, And Enantioselectivity In Town Creek, Sc, Usa Sediment Microcosms, Catherine P. Sumner 2024 Clemson University

Assessment Of Tce And Chiral Pcb Dechlorination Rate, Congener Diversity, And Enantioselectivity In Town Creek, Sc, Usa Sediment Microcosms, Catherine P. Sumner

All Dissertations

Polychlorinated biphenyls (PCBs) and trichloroethene (TCE) are ubiquitous contaminants and are recognized as persistent organic pollutants due to their extreme chemical stability. PCBs were manufactured by chlorinating biphenyls that created 209 congeners with various structures, of which 19 are chiral and can exist as a pair of stable atropisomers. PCBs have been known to cause developmental and neurological toxicity in humans and wildlife; they can act as endocrine disrupters, carcinogens, and teratogens. Sangamo Weston Inc. was an industrial plant located near Town Creek in Pickens Country, South Carolina, that manufactured capacitors and used Aroclors 1016 and 1254 as dialectic fluids …


Impact Of Imidacloprid On Forebrain Mitochondrial Enzymatic Activities Ec50, Ic50 And Impacts Of Mellissa Extracts, Sarra Zouaoui, Rachid Rouabhi, Chahinez Taib, Zina Bouteraa, Salim Gasmi, Brahim Benaicha, Nadjiba Toualbia 2024 Laboratory of Toxicology and Ecosystem Pathologies, Echahid Cheikh Larbi Tebessi University, Tebessa, Algeria

Impact Of Imidacloprid On Forebrain Mitochondrial Enzymatic Activities Ec50, Ic50 And Impacts Of Mellissa Extracts, Sarra Zouaoui, Rachid Rouabhi, Chahinez Taib, Zina Bouteraa, Salim Gasmi, Brahim Benaicha, Nadjiba Toualbia

Journal of Bioresource Management

Neonicotinoids are new generation of neuroactive pesticides, used against a wide specter of insect species, and many non-target beings are affected with these pesticides’ impacts. Our work was focused on the impact of 5, 10, 15, 20, 25 and 30 mg/kg of Imidacloprid the nicotinergic neuronal pathway inhibitor (N-ACh receptors) on the activities of mitochondrial detoxification enzymes (Catalase, SOD, GST and GPx) and acetylcholine esterase (AchE) in forebrain region of Wistar rats. Direct impact on enzymes activities was measured and the IC50, EC50 with or without Mellissa extracts were investigated. Our results showed that the IC50 of imidacloprid on …


A Study On Bioaccumulation Of Two Heavy Metals In Pastures Irrigated With Wastewater And Translocation In Grazing Ruminants Through Forages: Public Health Implications, Zafar Iqbal Khan, Kafeel Ahmad, Tasneem Ahmad, Kausar Parveen, Asma Ashfaq, Naila Riaz, Faiza Zubair, Hafsa Memona, Shahzadi Mahpara, Ijaz Rasool Noorka, Tooqeer Abbas, Humayun Bashir, Abid Ejaz, Shahzad Akhtar, Aima Iram Batool, Naunain Mehmood, Farzana Siddique, Muhammad Nadeem, Muhammad Umer Farooq Awan, Allah Bakhsh Gulshan, Tayyba Liaqat, Tayyaba Aziz, Natasha Ameer 2024 Department of Botany, University of Sargodha, Sargodha Pakistan

A Study On Bioaccumulation Of Two Heavy Metals In Pastures Irrigated With Wastewater And Translocation In Grazing Ruminants Through Forages: Public Health Implications, Zafar Iqbal Khan, Kafeel Ahmad, Tasneem Ahmad, Kausar Parveen, Asma Ashfaq, Naila Riaz, Faiza Zubair, Hafsa Memona, Shahzadi Mahpara, Ijaz Rasool Noorka, Tooqeer Abbas, Humayun Bashir, Abid Ejaz, Shahzad Akhtar, Aima Iram Batool, Naunain Mehmood, Farzana Siddique, Muhammad Nadeem, Muhammad Umer Farooq Awan, Allah Bakhsh Gulshan, Tayyba Liaqat, Tayyaba Aziz, Natasha Ameer

Journal of Bioresource Management

Copper and zinc play a very important role in plant development, but exposure at higher concentrations causes severe toxic effects. Copper (Cu) is an essential element for plants as it is involved in the synthesis of ATP and CO2 assimilation, while zinc (Zn) stimulates several enzymes and is necessary for the biosynthesis of chlorophyll. The present research appraised the Cu and Zn concentrations in water, soil, forages (Trifolium repens, Cynodon dactylon, Lolium perenne, and Festuca arundinacea), milk, and hair samples of buffaloes. The samples were collected from the selected sites of Tehsil Bhalwal Punjab, Pakistan, and analyzed through an …


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