Omega-3 Fatty Acids,
2020
Nova Southeastern University
Omega-3 Fatty Acids, Kristina Krupa, Kristina Fritz, Mayur S. Parmar
HPD Articles
No abstract provided.
Iron Dextran,
2020
Nova Southeastern University
Calcium Carbonate,
2020
Nova Southeastern University
Calcium Carbonate, Kristina Fritz, Katherine Taylor, Mayur S. Parmar
HPD Articles
No abstract provided.
Famciclovir,
2020
Nova Southeastern University
Doxycycline Hyclate,
2020
Nova Southeastern University
Doxycycline Hyclate, Reema S. Patel, Mayur S. Parmar
HPD Articles
No abstract provided.
Pramipexole,
2020
University Hospitals, Cleveland, OH
Human Genetics, Psychotropic Drugs, And Acts Of Violence,
2020
University of Denver
Human Genetics, Psychotropic Drugs, And Acts Of Violence, Selma Jolanda Eikelenboom-Schieveld
Electronic Theses and Dissertations
From the start of the use of psychoactive prescription medications in the 1950s, physicians reported paradoxical adverse reactions, ranging from newly developing depressions to an increase in existing mood disorders, and extremely violent and bizarre acts of suicide and homicide. In this research, it is hypothesized that the pharmacological properties of the prescribed drugs or the interaction between the drugs and the enzymes that are primarily responsible for their metabolism (cytochrome P450s) could cause these reactions. Given that acts of violence could be medication-induced, the role of the rate of drug metabolism is discussed. Genetic testing of certain CYP450s could …
Total Cellular Atp Production Changes With Primary Substrate In Mcf7 Breast Cancer Cells.,
2020
Department of Natural Sciences and Mathematics, Dominican University of California
Total Cellular Atp Production Changes With Primary Substrate In Mcf7 Breast Cancer Cells., Maggie Louie, Justin Ton, Maurice L. Brady, Diem T. Le, Jordon N. Mar, Chad A Lerner, Akos A Gerencser, Shona A. Mookerjee
Natural Sciences and Mathematics | Faculty Scholarship
Cancer growth is predicted to require substantial rates of substrate catabolism and ATP turnover to drive unrestricted biosynthesis and cell growth. While substrate limitation can dramatically alter cell behavior, the effects of substrate limitation on total cellular ATP production rate is poorly understood. Here, we show that MCF7 breast cancer cells, given different combinations of the common cell culture substrates glucose, glutamine, and pyruvate, display ATP production rates 1.6-fold higher than when cells are limited to each individual substrate. This increase occurred mainly through faster oxidative ATP production, with little to no increase in glycolytic ATP production. In comparison, non-transformed …
Variations On A Theme: Intricacies Of Unanchored Poly-Ubiquitin Signaling And Toxicity,
2020
Wayne State University
Variations On A Theme: Intricacies Of Unanchored Poly-Ubiquitin Signaling And Toxicity, Jessica Renee Blount-Pacheco
Wayne State University Dissertations
Ubiquitin is an 8.5 kDa post-translational modifier involved in essentially all eukaryotic cellular processes. Through a process called ubiquitination, ubiquitinating enzymes chemically attach ubiquitin to substrate proteins to control their fates, resulting in anything from their recruitment into signaling pathways to their proteasomal degradation, with a plethora of possibilities in between. Ubiquitin molecules can also be attached to one another, resulting in poly-ubiquitin chains with various effects depending on the number of ubiquitin molecules and the specific amino acid residues used to link them together. While most poly-ubiquitin in the cell exists as conjugated species, there are also untethered poly-ubiquitin …
Poly(Lactic-Co-Glycolic Acid) - Polyethylene Glycol Copolymer For Long-Acting Injectable: Synthesis, Characterization, And In-Vivo Study,
2020
Chulalongkorn University
Poly(Lactic-Co-Glycolic Acid) - Polyethylene Glycol Copolymer For Long-Acting Injectable: Synthesis, Characterization, And In-Vivo Study, Ravindra Kamble, Manasi Kulkarni, Swati Korake, Abhishek Pawar, Krishnat Dhekale
The Thai Journal of Pharmaceutical Sciences
Aim: This work was aimed to develop a carrier system of poly(lactic-co-glycolic acid) (PLGA) by using polyethylene glycol (PEG) for longer action in various diseases by preparing a di-block copolymer by using Risperidone (RSP) as a drug. Methodology: PLG.
Measuring The Potential Antioxidant Activity Of Methyl Gallate: Molecular Docking Study,
2020
Chulalongkorn University
Measuring The Potential Antioxidant Activity Of Methyl Gallate: Molecular Docking Study, Sutomo S, Mohammad Rizki Fadhil Pratama
The Thai Journal of Pharmaceutical Sciences
Objectives: This study aims to obtain predictions of the interactions that occur between methyl gallate and various antioxidant receptors while comparing it with gallic acid as its parent compound. Materials and Methods: The protein crystal structures of.
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations,
2020
Chulalongkorn University
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
The Thai Journal of Pharmaceutical Sciences
Purpose: The objective of the present study is to assess the antimicrobial activity of gastroretentive formulation for moxifloxacin HCl and in vitro antimicrobial evaluation using the cup-plate method. Materials and Methods: Gastroretentive floating tabl.
Development And Validation Of Rp-Hplc Method For Simultaneous Determination Of Ondansetron Hydrochloride And Granisetron Hydrochloride In Their Admixtures With Pantoprazole Sodium,
2020
Chulalongkorn University
Development And Validation Of Rp-Hplc Method For Simultaneous Determination Of Ondansetron Hydrochloride And Granisetron Hydrochloride In Their Admixtures With Pantoprazole Sodium, Al Montaser Hamed Bellah, Abdel Maaboud Ismail Mohamed, Niveen Abdel-Latif Mohamed
The Thai Journal of Pharmaceutical Sciences
Objective: Development of rapid and sensitive high-performance liquid chromatography method for the quantification of ondansetron hydrochloride and granisetron hydrochloride in their admixtures with pantoprazole sodium in its dosage form using ketorolac .
The Effects Of Ball Mill Processing On The Physicochemical Properties Of Glutinous Rice Starch,
2020
Chulalongkorn University
The Effects Of Ball Mill Processing On The Physicochemical Properties Of Glutinous Rice Starch, Weeraya Tharanon, Jomjai Peerapattana
The Thai Journal of Pharmaceutical Sciences
Glutinous rice starch (GRS) (Oryza sativa L.) is a product derived from a staple food that is commonly cultivated and consumed in Asia. This study investigates the effect of physical modification by planetary ball mill processing on some physicochemical .
Anti-Tyrosinase And Anti-Melanogenic Potential Of Shallots (Allium Ascalonicum) From Various Cultivation Sites In Thailand,
2020
Chulalongkorn University
Anti-Tyrosinase And Anti-Melanogenic Potential Of Shallots (Allium Ascalonicum) From Various Cultivation Sites In Thailand, Thidarat Phetmanee, Thaniya Wunnakup, Thitiya Lukkunaprasit, Fameera Madaka, Sukanya Settharaksa, Narisa Kamkaen, Nirun Vipunnqeun, Laksana Charoenchai
The Thai Journal of Pharmaceutical Sciences
Objectives: The present study aimed to investigate the anti-tyrosinase effect of shallots (Allium ascalonicum) in Thailand and to prepare an optimised shallot extract for use as a skin-lightening agent. Materials and Methods: Aqueous and ethanolic shallo.
In Silico Discovery Of Potential Diagnostic Biomarkers Of Lung Cancer,
2020
Chulalongkorn University
In Silico Discovery Of Potential Diagnostic Biomarkers Of Lung Cancer, Ruzianisra Mohamed, Raja Nur Hidayah Raja Hasnan
The Thai Journal of Pharmaceutical Sciences
Introduction: Understanding hub genes implicated in lung cancer (LC) metastasis will help in finding effective ways to diagnose and cure cancer. Accurate identification of protein biomarkers helps in improving the prognosis of LC. Here, the focus of this.
Progress In Erectile Dysfunction Therapy Through Drug Delivery System,
2020
Chulalongkorn University
Progress In Erectile Dysfunction Therapy Through Drug Delivery System, Mayuri Shitole, Shailesh Dugam, Rahul Tade, Neha Desai, Sopan Nangare
The Thai Journal of Pharmaceutical Sciences
A man’s aptitude to acquire and continue an erection is frequently equated with masculinity and virility and can greatly influence men’s confidence. The sexual healthiness is a significant determinant of the worth of life. Erectile dysfunction (ED) a...
In Silico Screening Of Natural Compounds To Identify Lead As Interleukin 17a Receptor Blockers As Antihypertensive Agents,
2020
Chulalongkorn University
In Silico Screening Of Natural Compounds To Identify Lead As Interleukin 17a Receptor Blockers As Antihypertensive Agents, Jimish R. Patel, Hirak V. Joshi, Ujashkumar A. Shah, Jayvadan K. Patel
The Thai Journal of Pharmaceutical Sciences
Objectives: Nature gives disease and nature gives the medicine. Natural products have exhibited paramount sources of novel drugs. Due to this, natural products have gained a dominant role in drug design and discovery. Interleukin 17 (IL-17) is a potent p.
Chemical Composition Of The Essential Oil Of Several Iris Species,
2020
Chulalongkorn University
Chemical Composition Of The Essential Oil Of Several Iris Species, Olha Mykhailenko N/A, Volodymyr Kovalyov, Tetyana Orlova
The Thai Journal of Pharmaceutical Sciences
The essential oil was obtained by a steam distillation from the dried leaves of Iris germanica L., Iris versicolor L., Iris graminea L., and Iris halophila Pall. (Iridaceae) and was investigated by a gas chromatography-mass spectrometry (GC/MS) method. I.
Anthelmintic Activity Of Mansoa Alliacea Against Pheretima Posthuma: In Vitro And In Silico Approach,
2020
Chulalongkorn University
Anthelmintic Activity Of Mansoa Alliacea Against Pheretima Posthuma: In Vitro And In Silico Approach, D.S. N. B. K. Prasanth, S. K. Aminabee, Atmakuri Lakshmana Rao, Nayudu Teja, Koti Bhargavi, Chigurupati Monika, Boppudi Pujitha, Tera Sandhya, Agastya Lalitha, Siva Prasad Panda
The Thai Journal of Pharmaceutical Sciences
Objectives: Mansoa alliacea has been utilized to remedy many afflictions of humans. Literary works illustrate that it possesses numerous biological activities. Our analysis work aims to distinguish phyto-derived anthelmintic substances from M. alliacea a.
