Nutrition Commons^™

The Impact Of Folate Deficiency On The Base Excision Repair Pathway: Analysis Of Enzyme Coordination In Response To Dna Damage And Imbalanced Repair, Amanda Pilling

Wayne State University Dissertations

The condition of folate deficiency has been implicated in carcinogenesis, with the strongest evidence formulated in colon cancer. The role of folate in DNA repair, DNA synthesis and methylation reactions renders this nutrient an valuable target for studying the onset and progression of cancer. Using molecular techniques to determine gene and protein expression, enzyme activity and methylation status elucidates the mechanism of DNA repair and damage in folic acid deficient animals in response to carcinogen. The findings presented in this study indicate failure to remove and repair damage in the condition of folate deficiency and suggest that the accumulation of …

Base Excision Repair, Folate Deficiency And Cancer, Archana Unnikrishnan

Wayne State University Dissertations

Folate, an essential water soluble vitamin has been implicated in the etiology of many types of cancer especially colorectal cancer. Folate deficiency has been reported to incapacitate DNA repair pathways and thereby affect the genomic stability. Our lab has reported previously and here again through this research that folate deficiency affects the DNA damage inducibility of base excision repair pathway. Our study shows the differential effect folate deficiency has on the expression of the genes involved in this pathway. Further, our study shows the increase in preneoplastic lesions in the colon of mice exposed to folate deficiency in response to …

Assessment, Referral, And Self Perception In Binge Eating And Obesity Among Adults, Mary Solberg

Walden Dissertations and Doctoral Studies

In the past 30 years, binge eating and obesity has increased among all age groups due to lifestyle, environment, social, and biological reasons. To change eating habits, individuals may have to collaborate with others beyond the medical professional. Societal impacts of binge eating and obesity include increases in insurance rates, medical costs, and increased early-age mortality. The purposes of this study were to assess how individuals are referred to other professionals if they self-identify as binge eaters or obese and to understand personal awareness individuals had of binge eating and obesity. Cognitive behavioral theory was used as the theoretical foundation. …

A Framework For Monitoring Local And Regional Food Systems, Heather Victoria Davis

Capstone Collection

The US food system has been experiencing gradual, yet significant, changes in recent years - with many people recognizing that conventional approaches are not only unsustainable, but also detrimental. As an alternative paradigm, the development of local food systems has been flourishing because of the benefits they bring to us: more local control over our food; supporting the local economy and entrepreneurs; healthier food options; fewer “food miles” and the related benefits of lowered use of petroleum; stronger community bonds; job creation for our rural communities; more gentle on the environment; and a more secure food system overall. Monitoring the …

Factors Associated With Fruit And Vegetable Consumption Among Caribbean Immigrants In The United States, Claudia Martin-Ayoade

Master's Theses and Doctoral Dissertations

Background: There are limited data available on the fruit and vegetable consumption of Caribbean immigrants in the United States.

Purpose: To assess changes in intakes of fruits and vegetables in Caribbean immigrants while assessing knowledge of the recommended servings and barriers to intake.

Method: A cross sectional Internet questionnaire was conducted for Caribbean-born members of the social network website Cariblifecentral.com. Data were analyzed using descriptive frequencies, Pearson’s chi-square, and the Student’s t-test.

Results: Of 113 respondents, 37 reported consuming less vegetables since emigrating (p<0.10) while 29 reported eating more. However, 10.8% of respondents did not know the recommended servings for vegetables. Access to fresh produce was no barrier to consumption.

Conclusions: As this population continues to grow, it becomes necessary to tailor nutrition and disease prevention …

Walk The Talk, Winston J. Craig

Lake Union Herald

No abstract provided.

The Healthy Monday Campaign: Health Awareness In Elementary Schools, Sheena Pravin Patel

Theses and Dissertations--Nutrition and Food Systems

Childhood obesity is a major public health concern for Americans. Many school-based health interventions and campaigns have been in place in the elementary school setting to help lower the rates of childhood obesity and to make students aware of their health. This study focuses on the implementation of the Healthy Monday campaign to fourth and fifth grade students in two Kentucky elementary schools. Particularly the focal points of the campaign consist of nutrition and physical activity. The campaign highlights two spin-off campaigns from the Healthy Monday campaign titled the Monday Mile and Meatless Monday. This study looks at the effectiveness …

The Differential Effects Of Genetic And Dietary Alterations In Folate Status On Prefrontal Cortical Functions, Jessica Amanda Ash

Legacy Theses & Dissertations (2009 - 2024)

Folate status plays an essential role in embryogenesis and brain development; however, its importance in supporting cognitive functioning throughout adulthood is less clear. The present study was interested in examining the effects of genetic and dietary alterations in folate status on prefrontal cortical functions in mice, modeling a common polymorphism in the MTHFD1 gene in folate metabolism. A factorial design was used crossing two genotypes (mice with a gene trap insertion in the Mthfd1 gene exhibiting 50% decreased Mthfd1 expression: Mthfd1gt/+ mice or wildtype mice) with two levels of dietary folate (folate sufficient or folate deficient). The mice were tested …

Effects Of Dietary Fat Saturation On Lipoprotein Metabolism In Rodents And Humans, Deepinder Kaur

Wayne State University Dissertations

Consumption of trans-fatty acids (tFA) and saturated fatty acids (SFA) have been associated with higher incidence of coronary heart disease. Experimental and observational data suggests that consumption of PHVO containing tFA, like SFA leads to increased total cholesterol and LDL-cholesterol (LDL-C) but compared to tFA, SFA raises HDL-cholesterol (HDL-C). An attempt to eliminate PHVO from the food supply has resulted in the need to find alternatives which despite their higher dietary fat saturation as compared to naturally occurring vegetable oils, may be preferable to PHVO. However, amongst SFA, the effects on plasma lipoproteins are variable. Thus, we hypothesized that specific …

Action Anthropology And Pedagogy: University-Community Collaborations In Setting Policy, Sandra D. Lane, Robert A. Rubenstein, Lutchmie Narine, Inga Back, Caitlin Cornell, Alexander Hodgens

Falk College Research Center

This article describes a student-led, community-participatory project focused on reducing the burden of childhood lead poisoning in rental housing. A multidisciplinary group of students and faculty worked with community members. We compiled the social, public health, economic, and policy information on the human and fiscal costs of childhood lead poisoning. This analysis was done for community advocates to use to persuade policymakers to enact a local law strengthening the prevention of childhood lead poisoning in rental property. In conducting this work, the students gained experience in qualitative research methods, quantitative data analysis, the health consequences of lead exposure, health policy, …

Contents, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Instructions For Authors, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Traditional Open-Bay Versus Single-Family Room Neonatal Intensive Care Unit: A Comparison Of Selected Nutrition Outcomes, Christina Erickson, Kendra Kattelmann, Jessica Remington, Cuirong Ren, Carol C. Helseth, Dennis C. Stevens

Health and Nutritional Sciences Faculty Publications

Background: In contrast to the traditional open-bay–type design of the neonatal intensive care unit (tNICU), infants in developmentally appropriate NICU (dNICU) are housed in individual rooms with greater control of light and noise. Previous reports have documented positive influence of the dNICU in cardiorespiratory status, physiologic stability, and weight gain of the infants. The objective of this study was to explore selected nutrition outcomes of infants in the dNICU versus tNICU. Method: A prospective cohort study was conducted on infants with birth weight of 1500 g or less cared for in dNICU (n = 42) or tNICU (n = 31). …

Nutrition Assessment And Intervention Improves Body Composition And Diet In Ncaa Female Volleyball Players, Rachel Wenzel

Electronic Theses and Dissertations

Intercollegiate volleyball is a powerful sport that consists of two to three hour matches; therefore, optimal physical condition is critical for top performance. This study assessed nutrition and anthropometric parameters at the start and conclusion of both the spring 2009 (no intervention) and spring 2010 (intervention) off-seasons as well as additional measurements four months after the intervention. The subject' body composition, total energy, carbohydrate and protein needs were calculated and intakes were assessed. The intervention consisted of monthly individual nutrition counseling sessions based on analysis of intake from three-day food records. Food records were analyzed using Nutrient Data System for …

Mechanisms Of Decreased Cholesterol Absorption Mediated By Phytosterols In The Intestinal Lumen, Andrew W. Brown

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Phytosterols and their fatty acyl esters have been known for decades to lower LDL cholesterol, making them powerful nutraceuticals in lowering cardiovascular disease risk. The mechanisms by which phytosterols lower cholesterol, though, have been incompletely characterized. Three studies were executed to examine three aspects of cholesterol and phytosterol interactions in the intestinal lumen. In the first study, the ability of pancreatic cholesterol esterase to hydrolyze phytosterol esters was examined. Pancreatic cholesterol esterase hydrolyzed phytosterol esters, but the rate of hydrolysis proved sensitive to the structures of both the sterol and ester components. In the second study, cholesterol micellarization was challenged …

Forgotten Foods: The Impact Of Western Development On Eating Habits Among Women In Dehradun, India, Stephanie L. Leite

Capstone Collection

This paper investigates the impact that Western development has had on eating habits among women living in the greater Dehradun area of India over the last century. Research was undertaken while working at Bija Vidyapeeth, an organic farm and educational center operated by the Indian-based Non-Governmental Organization, Navdanya. Primary data was collected by interviewing twelve women from four families, spanning three generations and ranging in age from 106 to 20. Two of the four families live in the urban center of Dehradun, while the other two families practice farming outside the city limits. Interviews revealed a generational change in eating …

Letter From The Dean, Michael Vayda

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 12 2011, Several Authors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

The Impact Of Nutrition-Teaching Self-Efficacy On Daily Fruit And Vegetable Intake, Leslie E. Rawls Hoglund

Walden Dissertations and Doctoral Studies

Lack of fruit and vegetable (FV) consumption is directly linked to the prevalence of obesity and chronic disease in the United States. The USDA Fresh Fruit and Vegetable Program (FFVP) offers elementary school teachers access to healthy foods as part of the public school classroom experience. The purpose of this study---which was based on self-efficacy theory and the socio-ecological model---was to examine if an association exists between selected factors: (a) daily fruit and vegetable consumption, training status in the USDA Fresh Fruit and Vegetable Program (FFVP), and an established school nutrition policy and (b) nutrition-teaching self-efficacy (NTSE) among elementary school …

Long-Term Effects Of A Protein-Enriched Diet On Blood Pressure In Older Women, Jonathon Hodgson, Kun Zhu, Joshua Lewis, Deborah Kerr, Xingqiong Meng, Vicky Solah, Amanda Devine, Colin Binns, Richard Woodman, Richard Prince

Research outputs 2011

Short-term randomised, controlled trials have found that dietary protein relative to carbohydrate can reduce blood pressure. Our objective was to investigate the effects on blood pressure of an increase in protein intake from whey over 2 years in women aged over 70 years. From the general population, 219 women aged between 70 and 80 years were recruited to a 2-year randomised, double-blind, placebo-controlled parallel-design trial: 181 women completed the trial to the end of year 2. Participants were randomly assigned to consume a daily whey protein-based beverage (protein) or an energy-matched low-protein high-carbohydrate beverage (control). Blood pressure measurements were performed …