From The Human To The Planetary: Speculative Futures Of Care,
2019
CUNY Graduate Center
From The Human To The Planetary: Speculative Futures Of Care, Miriam Ticktin
Publications and Research
This is largely a theoretical, speculative essay that takes on the question of what ‘care’ looks like at a moment when climate change is increasingly taking center stage in public and political discussions. Starting with two new practices, namely, humanitarian care for nonhumans and One Health collaborations, I seek to determine what forms of political care can incorporate the well-being of future generations and future iterations of the earth. After an exploration of One Health as an approach to planetary care, I ask what its parts enable us to think, despite its limitations; I focus on the new human-nonhuman assemblages …
Overexpression Of Corticotropin-Releasing Factor In The Nucleus Accumbens Enhances The Reinforcing Effects Of Nicotine In Female Versus Male Rats.,
2019
University of Texas at El Paso
Overexpression Of Corticotropin-Releasing Factor In The Nucleus Accumbens Enhances The Reinforcing Effects Of Nicotine In Female Versus Male Rats., Uribe, Victor Correa, Briana Pinales, Rodolfo Flores, Bryan Cruz, Zhiyin Shan, Adriaan Bruijnzeel, Arshad Khan, Laura O'Dell
Departmental Papers (Biology)
This study assessed the role of stress systems in the nucleus accumbens (NAc) in promoting sex differences in the reinforcing effects of nicotine. Intravenous self-administration (IVSA) of various doses of nicotine was compared following overexpression of corticotropin-releasing factor (CRF) in the NAc of female and male rats. Ovariectomized (OVX) females were also included to assess the role of ovarian hormones in promoting nicotine reinforcement. Rats received intra-NAc administration of an adeno-associated vector that overexpressed CRF (AAV2/5-CRF) or green fluorescent protein (AAV2/5-GFP). All rats were then given extended access (23 h/day) to an inactive and an active lever that delivered nicotine. …
A Computational Study Of Sleep And The Hemispheres Of The Brain,
2019
University of Missouri-St. Louis
A Computational Study Of Sleep And The Hemispheres Of The Brain, Tera Ashley Glaze
Dissertations
Sleep and sleep cycles have been studied for over a century, and scientists have worked on modeling sleep for nearly as long as computers have existed. Despite this extensive study, sleep still holds many mysteries. Larger and more extensive sleep-wake models have been developed, and the circadian drive has been depicted in numerous fashions, as well as incorporated into scores of studies. With the ever-growing knowledge of sleep comes the need to find more ways to examine, quantify, and define it in the context of the most complex part of the human anatomy – the brain. Presented here is the …
Altering Social Cue Perception Impacts Honey Bee Aggression With Minimal Impacts On Aggression-Related Brain Gene Expression,
2019
University of Kentucky
Altering Social Cue Perception Impacts Honey Bee Aggression With Minimal Impacts On Aggression-Related Brain Gene Expression, James W. Harrison, Joseph H. Palmer, Clare C. Rittschof
Entomology Faculty Publications
Gene expression changes resulting from social interactions may give rise to long term behavioral change, or simply reflect the activity of neural circuitry associated with behavioral expression. In honey bees, social cues broadly modulate aggressive behavior and brain gene expression. Previous studies suggest that expression changes are limited to contexts in which social cues give rise to stable, relatively long-term changes in behavior. Here we use a traditional beekeeping approach that inhibits aggression, smoke exposure, to deprive individuals of aggression-inducing olfactory cues and evaluate whether behavioral changes occur in absence of expression variation in a set of four biomarker genes …
Network Structure And Dynamics Of Biological Systems,
2019
University of Nevada, Reno
Network Structure And Dynamics Of Biological Systems, Deena R. Schmidt
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Analog Implementation Of The Hodgkin-Huxley Model Neuron,
2019
Illinois State University
Analog Implementation Of The Hodgkin-Huxley Model Neuron, Zachary D. Mobille, George H. Rutherford, Jordan Brandt-Trainer, Rosangela Follmann, Epaminondas Rosa
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Impact Of Remembering Vs. Knowing On Strength Of Belief In Neuromyths,
2019
Western Kentucky University
Impact Of Remembering Vs. Knowing On Strength Of Belief In Neuromyths, Kailee Jackola
Mahurin Honors College Capstone Experience/Thesis Projects
As technology advances, misinformation can be spread easier than ever before. Many things the general public believe to be true are either completely false or contradict research findings. However, many people are not willing to give up their belief in false information, even if there is evidence to refute it. Neuromyths are a particular type of widespread misinformation involving incorrect beliefs about brain function (e.g., people can be either left-or right brained). Understanding the origins of neuromyths is important, because it may relate to the strength of individuals’ belief in these myths. Therefore, it is important to determine whether remembering …
Voltage-Gated Potassium Channels Are Critical For Infrared Inhibition Of Action Potentials: An Experimental Study,
2019
Case Western Reserve University
Voltage-Gated Potassium Channels Are Critical For Infrared Inhibition Of Action Potentials: An Experimental Study, Junqi Zhuo, Matthew T. Mcpheeters, Michael W. Jenkins, Hillel J. Chiel
Faculty Scholarship
Thermal block of unmyelinated axons may serve as a modality for control, suggesting a means for providing therapies for pain. Computational modeling predicted that potassium channels are necessary for mediating thermal block of propagating compound action potentials (CAPs) with infrared (IR) light. Our study tests that hypothesis. Results suggest that potassium channel blockers disrupt the ability of IR to block propagating CAPs in Aplysia californica nerves, whereas sodium channel blockers appear to have no significant effect. These observations validate the modeling results and suggest potential applications of thermal block to many other unmyelinated axons.
The Role Of The Visual Association Cortex In Scaffolding Prefrontal Cortex Development: A Novel Mechanism Linking Socioeconomic Status And Executive Function,
2019
University of Washington
The Role Of The Visual Association Cortex In Scaffolding Prefrontal Cortex Development: A Novel Mechanism Linking Socioeconomic Status And Executive Function, Maya L. Rosen, Dima Amso, Katie A. Mclaughlin
Neuroscience: Faculty Publications
Socioeconomic status (SES) is associated with executive function (EF) and prefrontal cortex (PFC) development. However, understanding of the specific aspects of SES that influence development of EF and the PFC remains limited. We briefly review existing literature on proposed mechanisms linking SES with EF. Then, we present a novel conceptual model arguing that early cognitive stimulation shapes EF and PFC development. We propose that cognitive stimulation drives lower-level sensory and perceptual processes that may impact EF and PFC development through reciprocal connections between the ventral visual stream and PFC. We argue that caregivers guide attention and associative learning, which provides …
Analysis Of Connectivity In Emg Signals To Examine Neural Correlations In Muscular Activation Of Lower Leg Muscles For Postural Stability,
2019
Grand Valley State University
Analysis Of Connectivity In Emg Signals To Examine Neural Correlations In Muscular Activation Of Lower Leg Muscles For Postural Stability, Diana Mccrumb
Masters Theses
In quiet standing the central nervous systems implements a pre-programmed ankle strategy of postural control to maintain upright balance and stability. This strategy is comprised of a synchronized common neural drive being delivered to synergistically grouped muscles. In this study connectivity between EMG signals of unilateral and bilateral homologous muscle pairs, of the lower legs, during various standing balance conditions was evaluated using magnitude squared coherence (MSC) and mutual information (MI). The leg muscles of interest were the tibialis anterior (TA), medial gastrocnemius (MG), and the soleus (S) of both legs. MSC is a linear measure of the phase relation …
Auditory And Vestibular Control Of Inverted Pendulum Dynamics In Spatial Orientation,
2019
Florida Institute of Technology
Auditory And Vestibular Control Of Inverted Pendulum Dynamics In Spatial Orientation, Lila Naheed Fakharzadeh
Link Foundation Modeling, Simulation and Training Fellowship Reports
Human standing balance requires continuously nulling the tendency to fall like an inverted pendulum, and this process relies on the convergence of information from multiple sensory modalities including vestibular, vision, audition, proprioception and somatosensation. Dynamic control of unstable balance is also a critical and difficult task in aviation and spaceflight. Pilots may lose orientation and vehicle control during unstable maneuvers like helicopter hovering in a degraded visual environment or during ambiguous vestibular signaling. It is therefore imperative to determine whether training with combinations of sensory modalities can aid the ability to balance in operational environments where some sensory signals can …
Neural Correlates Of Perceptual Switching While Listening To Bistable Auditory Streaming Stimuli,
2019
University of Nevada, Las Vegas
Neural Correlates Of Perceptual Switching While Listening To Bistable Auditory Streaming Stimuli, Nathan C. Higgins, David Frank Little, Breanne D. Yerkes, Karli M. Nave, Abin Kuruvilla-Mathew, M. Elhilai, Joel S. Snyder
Psychology Faculty Research
Understanding the neural underpinning of conscious perception remains one of the primary challenges of cognitive neuroscience. Theories based mostly on studies of the visual system differ according to whether the neural activity giving rise to conscious perception occurs in modality-specific sensory cortex or in associative areas, such as the frontal and parietal cortices. Here, we search for modality-specific conscious processing in the auditory cortex using a bistable stream segregation paradigm that presents a constant stimulus without the confounding influence of physical changes to sound properties. ABA_ triplets (i.e., alternating low, A, and high, B, tones, and _ gap) with a …
Influence Of Social Isolation During Prolonged Simulated Weightlessness By Hindlimb Unloading,
2019
NASA Ames Research Center
Influence Of Social Isolation During Prolonged Simulated Weightlessness By Hindlimb Unloading, Candice G.T. Tahimic, Amber M. Paul, Ann-Sofie Schreurs, Samantha M. Torres, Linda Rubinstein, Sonette Steczina
Publications
The hindlimb unloading (HU) model has been used extensively to simulate the cephalad fluid shift and musculoskeletal disuse observed in spaceflight with its application expanding to study immune, cardiovascular and central nervous system responses, among others. Most HU studies are performed with singly housed animals, although social isolation also can substantially impact behavior and physiology, and therefore may confound HU experimental results. Other HU variants that allow for paired housing have been developed although no systematic assessment has been made to understand the effects of social isolation on HU outcomes. Hence, we aimed to determine the contribution of social isolation …
Altered Gating Of KV1.4 In The Nucleus Accumbens Suppresses Motivation For Reward,
2019
University of Kentucky
Altered Gating Of KV1.4 In The Nucleus Accumbens Suppresses Motivation For Reward, Bernadette O'Donovan, Adewale Adeluyi, Erin L Anderson, Robert D. Cole, Jill R. Turner, Pavel I. Ortinski
Neuroscience Faculty Publications
Deficient motivation contributes to numerous psychiatric disorders, including withdrawal from drug use, depression, schizophrenia, and others. Nucleus accumbens (NAc) has been implicated in motivated behavior, but it remains unclear whether motivational drive is linked to discrete neurobiological mechanisms within the NAc. To examine this, we profiled cohorts of Sprague-Dawley rats in a test of motivation to consume sucrose. We found that substantial variability in willingness to exert effort for reward was not associated with operant responding under low-effort conditions or stress levels. Instead, effort-based motivation was mirrored by a divergent NAc shell transcriptome with differential regulation at potassium and dopamine …
Neural Correlates Of Decision Making Related To Information Security: Self-Control And Moral Potency,
2019
DePauw University
Neural Correlates Of Decision Making Related To Information Security: Self-Control And Moral Potency, Robert West, Emily Budde, Qing Hu
Publications and Research
Security breaches of digital information represent a significant threat to the wellbeing of individuals, corporations, and governments in the digital era. Roughly 50% of breaches of information security result from the actions of individuals inside organizations (i.e., insider threat), and some evidence indicates that common deterrence programs may not lessen the insiders’ intention to violate information security. This had led researchers to investigate contextual and individual difference variables that influence the intention to violate information security policies. The current research builds upon previous studies and explores the relationship between individual differences in self-control and moral potency and the neural correlates …
Murine Genetic Variance In Sugar And Fat-Conditioned Flavor Preferences: Roles Of Dopamine, Opioid And Nmda Receptors And Nutritive Sensing,
2019
CUNY Graduate Center
Murine Genetic Variance In Sugar And Fat-Conditioned Flavor Preferences: Roles Of Dopamine, Opioid And Nmda Receptors And Nutritive Sensing, Tamar T. Kraft
Dissertations, Theses, and Capstone Projects
As obesity and diabetes have emerged as a severe public health crisis, understanding the mechanisms underlying the consumption of sugars and fats has become a topic of vigorous study. From a biological standpoint, genetic dispositions, neurochemical and hormonal influences, and predetermined orosensory and postingestive signals that modulate the hunger and satiety process may govern physiological aspects of the obesity puzzle. In addition to an innate appetite and attraction for simple carbohydrates and fats, learning plays an important role in modulating preferences for sugar- and fat-rich foods in rodents, including inbred mouse strains. Marked genetic variance has been observed among murine …
The Interaction Of Attention And Memory On The Reorienting Negativity,
2019
CUNY Graduate Center
The Interaction Of Attention And Memory On The Reorienting Negativity, John C. Moses
Dissertations, Theses, and Capstone Projects
The three-stage model of distraction asserts that when we are presented with salient but task-irrelevant information, our sensory systems first detect the distracting stimulus by way of sensory memory buffers, which is indicated electrophysiologically by the mismatch negativity (MMN). Following detection, attentional resources are involuntarily allocated towards the processing of the distraction, as represented by the P3a. Finally, attentional resources are shifted away from the distracting stimulus and returned to the task-relevant information, as indicated by the reorienting negativity (RON). A great deal of research has focused on this last step in the model, largely centering around defining the mechanisms …
Development And Sensory Experience Dependent Regulation Of Microglia In Barrel Cortex,
2019
CUNY Queens College
Development And Sensory Experience Dependent Regulation Of Microglia In Barrel Cortex, Joshua C. Brumberg, John Kalambogias, Chia-Chien Chen, Safraz Khan, Titus Son, Carolyn Headlam, Cindy Lin
Publications and Research
The barrel cortex is within the primary somatosensory cortex of the rodent, and processes signals from the vibrissae. Much focus has been devoted to the function of neurons, more recently, the role of glial cells in the processing of sensory input has gained increasing interest. Microglia are the principal immune cells of the nervous system that survey and regulate the cellular constituents of the dynamic nervous system. We investigated the normal and disrupted development of microglia in barrel cortex by chronically depriving sensory signals via whisker trimming for the animals’ first postnatal month. Using immunohistochemistry to label microglia, we performed …
Visual Entrainment Of Perception-Related Neural Oscillations As A Mechanism For Maintaining Rhythmic Temporal Expectations Across A Wide Range Of Frequencies,
2019
CUNY Graduate Center
Visual Entrainment Of Perception-Related Neural Oscillations As A Mechanism For Maintaining Rhythmic Temporal Expectations Across A Wide Range Of Frequencies, Michael James Gray
Dissertations, Theses, and Capstone Projects
Visual sensitivity fluctuates rhythmically, in-synch with ongoing, EEG-recorded neural oscillations across a wide range of frequencies (~1-25hz). Some recent work has suggested that these perception-related neural oscillations can be entrained by rhythmic visual stimulation. Evidence is also emerging that the entrainment of ongoing oscillations in visual and auditory cortices is involved in rhythmic temporal expectations. In the introduction chapter, I attempt to bridge these bodies of literature and hypothesize that rhythmic visual stimuli automatically entrain ongoing, perception-related neural oscillations and that this mechanism supports the maintenance of rhythmic temporal expectations. Chapters 2 and 3 address this hypothesis from different angles. …
Neurogenesis Is Altered Between And Across Brain Regions After Neurodegeneration And Injury,
2019
CUNY Graduate Center
Neurogenesis Is Altered Between And Across Brain Regions After Neurodegeneration And Injury, Alice Perez
Dissertations, Theses, and Capstone Projects
Adult neurogenesis is the addition of new neurons in the adult brain. In mammals, neurogenesis is largely restricted to the hippocampus and olfactory bulb, which underlie learning, memory, and olfaction. In songbirds, new neurons are incorporated into telencephalic regions that subserve the production, perception, and maintenance of song. Studies of the regulation of neurogenesis have exclusively focused on a single brain region and within a single hemisphere. Interestingly, it has yet to be investigated whether there are correlations between numbers of new neurons across regions and hemispheres within the same animal. Here we examined these differences in a rat model …
