Cognitive Neuroscience Commons^™

Integrating Neuroaesthetic Design Into Brain-On-Chip Research: Toward Enhanced Neural Engagement And Cognitive Accessibility, Piper Hutson, James Hutson

Faculty Scholarship

This study examines the potential for neuroaesthetic design and adaptive neurofeedback principles to enhance brain-on-chip (BoC) research, with an emphasis on optimizing neural engagement and cognitive accessibility for diverse populations. Existing BoC platforms have transformed neuroscience through high-fidelity modeling of neural circuits, yet cognitive accessibility and sensory inclusion remain comparatively underexplored. Drawing upon recent studies in neuroinclusion, multisensory interface design, and adaptive feedback, this work synthesizes findings from biophilic interface architecture, neurofeedback literature, and embodied cognition frameworks. The manuscript outlines a multidisciplinary research agenda that prioritizes sensory diversity and ethical considerations in the evolution of BoC systems. Instead of making …

Addressing Anxiety In The Pediatric Population: An Ot Perspective, Joshua D. Johnson, Mary Jan Greer, Wendy Tremaine, Justine Faghihifar

Summer 2025 OTD Capstone Symposium

This capstone develops and evaluates a trauma-informed training for RBTs and caregivers in outpatient ABA clinics serving children with ASD and anxiety. Grounded in MOHO, the seven-module program teaches trigger→support mapping, sensory strategies, visual tools, and brief co-regulation routines. Findings show improved knowledge and confidence, with recommendations to embed a fidelity rubric, booster sessions, and ready-to-use templates.

The Effect Of An Acute Bout Of Rock Climbing On Cognitive Functioning And Cortisol Levels, Vanessa Steigauf

All NMU Master's Theses

Rock climbing is an understudied physical activity (PA) that demands active decision-making, integration of sensory and visual input, and continuous regulation of nervous system activity to produce complex motor outputs. The unique psychological demands of climbing warrant studying its effect on cognition and brain health. I recruited 26 generally healthy adults for a randomized-controlled study. Climbing experience, PA and perceived stress were self-reported. Each participant was randomly assigned to a climbing (10x2 minutes climb, moderate intensity) or control group (seated, watching climbing-related video). The primary outcomes, cognitive performance and salivary cortisol levels were assessed by the Stroop test. A linear …

Dermatoglyphic Fluctuating Asymmetry In Schizotypy, Marcus R. Thomas

All-Inclusive List of Electronic Theses and Dissertations

Schizotypy has been linked with many of the proposed endophenotypes of schizophrenia, but research is limited on the relationship between schizotypy and dermatoglyphic fluctuating asymmetry. The present study sought to examine relationships between schizotypy, dermatoglyphic fluctuating asymmetry, handedness, and season of birth. 146 undergraduate students were identified as schizotypes (n = 52) or controls (n = 94) based on the Multidimensional Schizotypy Scale and had their finger and palm prints collected along with completing additional measures of schizotypy and handedness. Schizotypes did not exhibit a greater degree of dermatoglyphic fluctuating asymmetry, negative schizotypy was associated with increased absolute finger ridge …

Electrophysiological Markers Of Emotion Dysregulation In Autistic Youth, Rachel G. Mcdonald

Theses, Dissertations and Culminating Projects

Emotion dysregulation (ED) is a transdiagnostic mechanism that is conceptualized as difficultly regulating emotions and deploying appropriate regulation strategies in response to environmental stimuli. Meta-analyses suggest that autistic people, across the lifespan, experience more severe ED as compared to both neurotypical people and those with mental health conditions. Despite elevated risk and evidence linking ED to disruptions in neural mechanisms, no studies to date have examined neural markers of ED in autistic populations. The current project uses multi-method and multi-informant measurement to examine similarities and differences in neural mechanisms of ED in autistic and non-autistic populations. Forty-four youth aged 11—17 …

Classification Of Human Trust In Ai Using Brain Activity Data, Danushka Bandara, Ruhuan Liao, Fatima Chowdhury, Leslie Abbott

Northeast Journal of Complex Systems (NEJCS)

Trust plays a crucial role in human-computer interaction, particularly in scenarios involving artificial intelligence (AI) systems. This study explores the feasibility of using functional near-infrared spectroscopy (fNIRS) data to classify trust levels in human-AI interaction scenarios. A total of 18 participants completed an image classification task with an AI team member while their hemodynamic responses were recorded using fNIRS. Preprocessing of fNIRS data involved motion artifact removal, filtering, and normalization. Exploratory analysis identified significant associations between hemodynamic responses in the prefrontal cortex and trust levels. An across-subject binary trust classification model was developed using machine learning techniques, achieving an F1 …

Art, Play, And Neuroplasticity: Advancing Dementia Care Through Art-Enriched Environments, Piper Hutson, James Hutson

Faculty Scholarship

Dementia represents a global public health crisis, characterized not only by progressive memory loss but by a pervasive decline in cognitive flexibility, social functioning, and overall quality of life. Traditional therapeutic modalities, often limited to pharmacological management and cognitive training, have yielded only modest gains in symptom mitigation and patient well-being. Recent advances in neuroscience have illuminated the brain‘s capacity for neuroplasticity—its inherent ability to adapt, reorganize, and form new neural connections even in advanced age and the presence of neurodegenerative conditions. This emerging understanding invites a critical re-evaluation of dementia care strategies, highlighting the potential of non-pharmacological interventions to …

The Sub-Syllabic Symphonies Of Self-Learning: How Do Zebra Finches Sing Them?, Abiesha Abiola Budiman

Dissertations, Theses, and Capstone Projects

Learning is a lifelong journey, where the mind and muscle dance to a tune of memory and motion. It begins at infancy and continues throughout life, encompassing everything from singing to achieving peak performance in sports. Complex motor skills involve multiple components and require coordination of several muscles. Humans and animals are extremely adept at learning complex motor skills on their own. However, we do not completely understand how self-directed learning works. One group of animals used to observe self-directed learning are songbirds. Zebra finches, Taeniopygia guttata, are one of the most studied songbird species due to their well-defined …

When Avatars Go To School: The Effect Of Virtual Reality On Learning And Error Correction, Lauren Barack

Dissertations, Theses, and Capstone Projects

The pandemic in 2020 led to an increasing dependency on technology particularly in learning environments. National educational assessments in the proceeding years have indicated steep, measurable learning loss. While a fully virtual learning environment is not the norm today, we chose to investigate how virtual reality (VR) environments influence learning in college students.

Our primary research goal was to look at how students learn and remember information gathered in virtual spaces. In particular, we examined whether sensory inputs in the VR environment, including spatial audio and haptic feedback, such as vibrations felt in a handheld controller, would help to better …

Memory Interference In The Lateral Entorhinal Cortex, Omar Ghazy

Dissertations, Theses, and Capstone Projects

Memory interference occurs when previously formed memories disrupt the acquisition or retrieval of new information. A prominent example of proactive interference is latent inhibition (LI), defined as a reduced ability to form or express Pavlovian associations with a stimulus following non-reinforced exposure. The interference-based model suggests that LI arises because the memory that the pre-exposed stimulus is inconsequential interferes with the memory that it predicts a reinforcer.

Because interference increases with age, identifying its neural basis may help prevent or slow cognitive decline. Prior studies using the LI paradigm implicate the entorhinal cortex (EC) in retrieving the memory that a …

The Manifestation Of Synesthesia In The Deaf, Hard-Of-Hearing, And Sign Language User Population, Elizabeth Droubi

Undergraduate University Honors Capstones

This capstone project investigated the prevalence and manifestation of synesthesia—a perceptual condition where stimulation in one sensory pathway triggers automatic, involuntary experiences in another—within d/Deaf, hard-of-hearing (DHH), and sign language user populations. Despite an estimated prevalence of over 4% in the general population and findings that many synesthetic experiences are language-based, little is known about how synesthesia presents across different language modalities, including signed languages. This project explored the phenomenon in two phases: an initial online survey assessing the prevalence and characteristics of synesthesia among DHH and signing individuals and follow-up interviews with self-reported synesthetes along with a test-retest procedure …

Capturing The Representational Dynamics Of Face Perception In Deep Recurrent Neural Networks, Hossein Adeli, Chase W. King, Nikolaus Kriegeskorte

MODVIS Workshop

We investigate the representational dynamics of recurrent convolutional neural networks (RCNNs) in order to understand the time-course of visual recognition. We explore a family of models with bottom-up and lateral connections that were optimized for face-identification and object-recognition tasks. Using representational similarity analysis (RSA), we observed that only models that were trained for face identification showed a late-emerging prominent distinction of identities as seen in the monkey face patch AM. Early model responses strongly separated the objects from the faces. These findings suggest that the dynamics of face recognition that emerges in a hierarchical recurrent neural network prioritizes category-level recognition …

Attention Improves Classification Performance Of Locations In Ventral And Dorsal Visual Pathways, Jinho Lee, Sung-Mu Lee, Ishita Agarwal, Anne Sereno

MODVIS Workshop

Visual processing is divided into a ventral and dorsal pathway, thought to be important for object recognition and spatial cognition, respectively. Yet both streams encode shape and spatial information, and both are modulated by attention and task demands. This study compared how attention influences fMRI bold responses in a ventral region (fusiform gyrus, FG) and dorsal region (superior parietal gyrus, SPG). Specifically, using multivariate pattern analysis within each region, we examined whether attention modulated spatial location classification performance. During fMRI scans, participants performed one of 3 possible tasks: a 1-back task under attend-to-shape (detect a shape repetition); a 1-back task …

Modeling Effects Of Edge Classification And Perceptual Organization On The Appearance Of Disk/Annulus Stimuli, Michael E. Rudd

MODVIS Workshop

In classical theories of sensory psychophysics, appearance matches conducted with simple stimuli consisting of disks surrounded by annuli were posited to probe low-level contrast mechanisms in the visual pathways that computed the approximate luminance ratio between the disk and annulus for the purpose of achieving lightness constancy (Wallach, 1948). Subsequent models have explained such matches on the basis of neural edge integration (Shapley & Reid, 1985; Rudd & Zemach, 2004). Here, I demonstrate that appearances matches made in the disk/annulus paradigm are influenced by at least two types of top-down effects involving edge classification and perceptual organization. I present a …

The Impact Of Insufficient Sleep On The Serial Reproduction Of Information, David L. Dickinson, Sean P. A. Drummond

ESI Publications

Story retelling is an important form of communication, cultural practice, and message transmission. Insufficient sleep is known to affect relevant cognitive skill areas necessary for story retelling or transmission fidelity. We conducted a preregistered randomized cross-over study on n = 155 young adults with exogenously assigned nightly sleep levels experienced in their at-home environments. A serial story reproduction task was administered online, and chains of up to three retells of a given story involved varied numbers of sleep restricted (SR) versus well-rested (WR) retellers. While story content decayed with each retell, group-level analysis showed that additional SR retellers in a …

Poor Sleep Quality Is Associated With Decreased Structural Coherence Of Mesolimbic Dopamine Projections In Children, William A. Walker

Psychological Science Undergraduate Honors Theses

Insomnia is the second most common mental disorder that affects approximately 10% of the population. An additional one-third of the population experiences occasional symptoms of insomnia like difficulty falling asleep or staying asleep. Sleep quality is also a key indicator of overall mental and physical health; however, researchers have only begun to study the effects of the structure of the mesolimbic pathway on sleep cycle regulation and quality. Emerging research suggests that mesolimbic dopamine projections from the Ventral Tegmental Area (VTA) to the Nucleus Accumbens (NAcc) play a role in sleep-wake regulation. In this study, I analyzed data from the …

Effects Of The Non-Stimulant Norepinephrine Reuptake Inhibitor, Atomoxetine, On Cognitive Flexibility In Healthy Adult Long-Evans Rats, Noah A. Ivak, Samantha Walkow, Christopher Knapp, Eleni Papadopoulos, Barry D Waterhouse, Rachel L Navarra

Rowan-Virtua Research Day

Executive function is the control of multiple higher order cognitive processes that include attention, working memory, and cognitive flexibility. Cognitive flexibility is the ability to shift behavioral strategies

in response to changing environmental demands and task complexity. This cognitive modality is often impaired in many neuropsychiatric disorders like attention deficit hyperactivity disorder (ADHD). Deficits in cognitive flexibility are associated with dysregulation of the catecholamines, norepinephrine (NE) and dopamine (DA) within the prefrontal cortex (PFC). Atomoxetine (ATX), a non-stimulant NE reuptake inhibitor, elevates levels of NE and DA in the PFC by inhibiting the norepinephrine transporter (NET). ATX is used to …

Effects Of Social Isolation On Cecum Opioid Receptor Expression And Affective Behavior, Jordan Riser, John Tkaczynski, Nicole Shellenbarger, Maya Patel, Daniel Chandler, Daniel Manvich

Rowan-Virtua Research Day

BACKGROUND

Psychological stress can induce gastrointestinal symptoms and exacerbate existing gastrointestinal disorders, indicating an interaction between the central and enteric nervous systems. Central nervous system activation of opioid receptors stimulates sympathetic outflow to the enteric nervous system, delaying motility and reducing gastrointestinal secretions, producing a similar clinical presentation to IBS.

HYPOTHESIS

We hypothesize that social isolation induces anxiety states, disrupting homeostatic noradrenergic activity in the brain and gut, leading to neurophysiological changes in the cecum characterized by altered expression of opioid receptors.

METHODS

Sprague-Dawley rats were housed in either group (control) or socially isolated conditions. Affective behavior was assessed using …

Simulating Chill: Exploring The Cognitive And Therapeutic Potential Of Cold Vr Environments, Jessica Turner, Piper Hutson, James Hutson

Faculty Scholarship

This study investigates the cognitive and therapeutic potential of immersive virtual reality (VR) environments designed to simulate cold conditions. Through the engagement of participants through multisensory stimuli—including vivid visual representations of the Athabasca Glacier, auditory effects of icy winds, and corresponding haptic feedback—the research evaluates neurological and physiological responses associated with attention, emotional regulation, and stress modulation. Participants experienced virtual scenarios featuring icy winds and snow, activating specific neurological pathways involving the occipital lobe, primary visual cortex, superior colliculus, and insula, thus reinforcing sensory integration. Through predictive coding, the anterior insula and hypothalamus were engaged, prompting thermoregulatory simulations and subconscious …

Neural Activity Within And Between Visual And Executive Areas Is Modulated Post-Locomotion In Rhesus Macaques, Sergey Egranov

Dissertations and Theses (Open Access)

Physical activity has been shown to benefit cognitive and mental health by improving cerebrovascular perfusion and regulating hormone-mediated processes on a systemic level. However, the acute effects of physical activity, such as locomotion, on the neuronal circuits underlying cognitive processes have yet to be fully characterized. This body of work seeks to rectify this gap in knowledge through analysis of how both behavioral performance and neuronal activity signatures in visual and executive brain regions are modulated post-locomotion in rhesus macaques.

To this end, we performed high-yield electrophysiological recordings simultaneously from area V4, a mid-tier visual cortical region, and the dorsolateral …