Cognitive Neuroscience Commons^™

Neurophysiological Signatures Of Perceived Control In The Human Brain: An Electroencephalography Study, Megan Staehling

Honors Theses

Perceived control is defined as the belief that one’s actions can influence the outcomes in the environment. It plays an important role in decision-making, motivation, and emotional regulation. Previous studies suggest that perceived control shapes how the brain processes both reward and punishment stimuli. However, the neural mechanisms underlying this process are still unclear. The present study examined the neurophysiological correlates of perceived control during a decision-making task. Electroencephalography (EEG) was used to record the neural activity of twenty-nine undergraduate students while they completed the Choice Task. Participants associated visual cues with different levels of control over trials involving monetary …

From Stranger To Self: The Role Of Familiarity In Modulating The N170 And N250 Erp Components, Tabish Gul

Dissertations

This study investigated how varying levels of face familiarity modulate the N170 and N250 event-related potential (ERP) components, two neural markers of face perception and recognition. While the N250 is widely considered familiarity-sensitive, the N170 has traditionally been linked to the structural encoding stage of face perception. However, recent research suggests that face familiarity may also influence N170 amplitude and latency. While most previous studies have compared up to three familiarity levels, the present study examined five levels of familiarity: own face, friend’s face, famous face, experimentally familiar face, and unfamiliar face. Twenty-six participants viewed face images while completing a …

Invisible Shipwrecks And Neurological Endangerment: The Trade-Off In Seeking Asylum - Reframing The Neurobiological Cost Of Forced Migration, Eisha Giran

CISLA Senior Integrative Projects

Forced migration along the Spain–Morocco route represents one of the most visible humanitarian crises of the twenty-first century, yet its neurological dimensions remain insufficiently examined. This paper investigates how prolonged displacement and trauma reshape neural systems involved in stress regulation, memory, and emotional processing. It introduces the concept of neurological endangerment, defined as a condition of prolonged and inescapable threat exposure during forced migration in which stress-response systems remain chronically activated, opportunities for recovery are structurally constrained, and cumulative neurobiological risk persists beyond the period of immediate danger.

To address the gap between biological measurement and lived experience, this paper …

Neural Mechanisms Underlying Jung’S Active Imagination: A Review And Hypothesis, Charles R. Fox

Journal of Conscious Evolution

Active imagination is a key technique of Jungian analysis. Despite its centrality, and its potential importance beyond Jungian psychology to the area of systems neuroscience, psychology, and consciousness studies, there are no known neurological mechanisms underlying this psychological phenomenon. There is a history of using the types of mental imagery used in active imagination to explore consciousness. The development and use of active imagination is briefly reviewed, and a case is developed that the neurology underlying active imagination would be fruitfully explored by considering it a special case of mystical experience. Active imagination primarily uses the right hemisphere processing of …

The Influence Of Valence On Action Control: A Comparison Of Simon Effects In The Extrinsic Affective Simon Task (East) And The Spatial Simon Task, Yaara Aleissa

College of Arts & Sciences Senior Theses

People adjust their thoughts and actions in response to a changing environment every day and emotions may influence these actions. Understanding how emotion impacts action control in situations where emotion is central to the action (task-relevant) compared to when it is present in the environment as distracting information (task-irrelevant) is essential. Currently it is unclear when emotion most significantly modulates action control. This study seeks to compare how valence (positive versus negative emotion) impacts action control performance when valence is task-relevant and task-irrelevant by using two modified versions of the Simon conflict task.

The Simon task is a paradigm to …

Clinical And Demographic Characteristics Of Hospitalized Patients With Xylazine-Related Wounds, Elizabeth Novick, Nikhil Seval, Dagan Coppock, Mollie Tucker, Daniel Taupin, John Zurlo, Carolyn Kramer

Department of Medicine Faculty Papers

OBJECTIVES: Little is known about the demographic and clinical features of patients with xylazine-related wounds. We sought to characterize hospitalized patients with substance use disorder (SUD) and xylazine-related wounds seen for infectious diseases consultation.

METHODS: We retrospectively reviewed the medical records of 193 patients diagnosed with SUD at 3 Philadelphia hospitals between October 2023 and January 2024. Patients were identified as either being diagnosed with (n=73) or without (n=120) xylazine-related wounds. We compared the demographic and clinical features between the 2 groups.

RESULTS: Patients diagnosed with wounds were younger ( P < 0.001), more likely to be White or Hispanic and less likely to be Black/AA ( P < 0.001), more likely to have tested positive for fentanyl ( P < 0.001), amphetamines ( P < 0.001), and cocaine ( P 0.001), more likely to acknowledge injection ( P < 0.001), and more likely to leave the hospital by patient-directed discharge (PDD) ( P < 0.001). Most patients had multiple wounds (75%), and more than half (53%) had at least one wound greater than 10 cm at its widest dimension. Although most patients diagnosed with wounds received antibiotics, many did not have symptoms or signs of infection.

CONCLUSIONS: Xylazine-related wounds are highly associated with illicitly manufactured …

Neurobiological Mechanisms Of Attention In Adolescents, Virginia Clark

All Dissertations

Adolescence is a transformative developmental period characterized by profound biological, neurological, and behavioral changes. This dissertation investigates the neurobiological underpinnings of attention in adolescents, emphasizing how internal mechanisms influence and individually shape cognitive development through the endosystem. Rooted in the intersection of human development, learning sciences, and cognitive neuroscience, this work argues for a more integrated understanding of attention as a fundamental cognitive function for learning, one that is behaviorally seen but also biologically and neurologically driven. While developmental science has often emphasized external influences such as family, culture, and environment, this work centers on the adolescent’s internal biological systems …

Eeg Studies Of Pre-Stimulus Activity During Turn-Taking In Naturalistic Conversation, Seyedmohamadreza Manzourolajdad

Student Works (2020-2029)

This study integrates conversational analysis principles and neural activity to investigate natural cognition and examine event-related brain changes. A wireless electroencephalography (EEG) device was used in an ecological validity setting to analyse pre-stimulus brain activity preceding conversational turns. This study aims to identify aspects of the conversation that reflect its naturalness in the aspect of listening and the corresponding brain activity by analysing the signals before and after a turn in a conversation. This research contributes to an ecologically valid understanding of natural conversation as a social action that enables seamless communication. Seven Malaysian participants (aged 19–22, M=20.46) engaged in …

Impact Of Caffeine On Participant Memory For A Stressful Experience And The Development Of Intrusive Memories, Jaycee L. Kirkland, Kaylina R. Mcclenen, Natalina E. Porter, Sarah M. Wood, Julia Gross, Madilyn E. Paphanchith, Kelsey M. Siereveld, Jasmine Ic Ifeakanwa, Caeden M. Gurganus, Koen N. Suzelis, Aiden J. Farrell, Boyd R. Rorabaugh, Phillip R. Zoladz

ONU Student Research Colloquium

Most individuals consume caffeine on a daily basis. Research has shown that caffeine stimulates the release of glucocorticoids and catecholamines and can enhance cognition. Caffeine also amplifies stress-induced increases in arousal and aggravates PTSD-like symptoms. Thus, we examined the impact of caffeine on memory for a stressful experience and intrusive memories related to that experience. Undergraduate students ingested caffeine or a placebo. Thirty minutes later, they were exposed to the Trier Social Stress Test (TSST; stress condition) or friendly-TSST (f-TSST; control condition), both of which were designed to enable participant memory for the experiences to be quantified. In each condition, …

Relish As A Temporal Switch In Neurodegeneration Using Drosophila Melanogaster, Kyle M. Johnson

Create@State

Neurodegenerative diseases are often linked to chronic inflammation in the nervous system, but it is still unclear what triggers this process during the early stages of disease. This project examines whether activation of the NF-κB transcription factor Relish may act as a temporal switch that contributes to early neurodegenerative stress in Drosophila melanogaster. As a result of many innate immune pathways are consistent between flies and humans, Drosophila serves as a useful model for studying how immune signaling affects neuronal health. In this study, neural driver lines were crossed with control strains to evaluate how changes in Relish signaling …

Subjective Feelings And Electrophysiological Responses To Love-Stimuli In Parasocial And Real-Life Romantic Love, Magda Martinez-Mata

Theses

People can have a crush on, fall in love with, or develop a romantic interest in media figures despite having no reciprocal interaction, which is known as parasocial love. The objective of this study was to evaluate subjective feelings for and event-related potential (ERP) responses reflecting attention to the parasocial beloved and to compare them to real-life love. Twenty-six participants who have a parasocial beloved were recruited. Sixteen of those had a real-life beloved as well. The participants answered questions about their love feelings and completed the Infatuation and Attachment Scales and the Parasocial Love Scale for both their parasocial …

Cognitive And Mental Health Challenges: Addressing The Impact Of Traumatic Brain Injuries In Adults, Hannah E. Smith, Lesley Khan-Farooqi, Phd, Otd, Otr, Anne Mcdonnell, Mpa, Otr/L, Cbist

Student Capstone Papers

This capstone examined the challenges adults face following traumatic brain injuries (TBIs) and explored interventions aimed at enhancing cognitive functioning and mental health. This capstone also aimed to reduce caregiver stress and burnout by expanding knowledge and resources focused on cognitive and mental health within the population. TBIs can result from a variety of causes, affecting cognitive abilities, mental health, and functional outcomes. This capstone shows evidence-based interventions designed to improve cognitive functioning, facilitate engagement in meaningful activities to improve mental health, and enhance overall quality of life for adults recovering from TBI. This also will demonstrate potential for occupational …

The Mental Advantage: The 10 Disciplines That Separate The Elite From The Average, Scott Williams

Doctor of Strategic Leadership (DSL) Capstone Abstracts

Title of Project

The Mental Advantage: The 10 Disciplines That Separate the Elite from the Average

Defense Date

April 1, 2026

Candidate Name

Scott Williams

Personal Email Address

[email protected]

First Advisor

Dr. Joshua Henson, PhD

Second Advisor

Dr. Michael Steiner, PhD

DSL Final Project Abstract

Project Type

This project was a book manuscript designed to develop and present a practical leadership framework for high-performance individuals and organizations.

Project Overview

This project explored the concept of Elite Mental Execution™ as a structured framework for understanding and developing high-performance leadership. Drawing from nearly three decades of professional experience in leadership, executive coaching, …

The Evolution Of Self-Awareness In Conscious Organisms, Robert A. Dielenberg

Journal of Conscious Evolution

Self-awareness in conscious organisms remains an enduring puzzle for philosophers and neuroscientists. This paper proposes a tripartite evolutionary model tracing its emergence through three sequential types: the sensory self (primitive egocentric, valence-tagged awareness of sensory states), the bodily self (external objectification of the body as a distinct entity, evidenced by mirror self-recognition in select species), and the cognitive self (internal objectification of the mind enabling recursive self-transformation). Adopting a monist framework, the model treats consciousness as the biological substrate of delayed neural apperception (the “Delayed Present”), within which selves emerge as increasingly sophisticated models. It distinguishes non-human metacognition—implicit, online regulation—from …

Hallucinogens For Mood And Anxiety Disorders: A Critical Review Of Psychedelic-Assisted Therapies, Georgia Chlebek

The Cardinal Edge

In quite a few people worldwide, there are several mental disorders that prevent the brain from operating in the “proper” way, depression, anxiety, and post-traumatic stress disorder (PTSD) being among the most common. Luckily, there are several medications that are produced and used to treat these disorders, but some medications are hard to access, and others simply don’t help the patient. Firstly, these medications take time to study and prove safe for public use, though in some cases time is not readily available. In other cases, these medications are going through shortages and becoming increasingly difficult for patients to access …

Circuit And Synaptic Mechanisms Of Methamphetamine Induced Cognitive Deficits During Abstinence: Roles Of The Perirhinal-Prefrontal Pathway And The Nucleus Reuniens, Sarah Goldsmith

MUSC Theses and Dissertations

Cognitive deficits during abstinence are a hallmark of methamphetamine (meth) use and indicative of negative treatment outcomes. In rats, both long access meth self-administration and meth binge produce recognition memory deficits due to drug-induced plasticity within the perirhinal cortex (PRH). PRH projections are numerous and include the medial prefrontal cortex (mPFC) and the Nucleus Reuniens (NRe). In the first study, the role of the PRH-mPFC reciprocal circuit in novel object recognition memory was investigated by infusing an rgAAV encoding GFP-tagged Cre recombinase into the PRH or the mPFC. Following surgery, rats explored objects. During exploration, PRH neurons receiving input from …

Somatosensory Cortex Responses To Illusory Touch In A Visual-Tactile Integration Task, Aditi Surendra Pawar

Dissertations, Theses, and Capstone Projects

Perceptual illusions arising from multisensory integration reveal how the brain constructs subjective experience from sensory input, and provide a powerful means of allowing the investigation of neural processes that track perceptual interpretation rather than physical stimulation alone. While visual illusions induced by auditory or tactile stimuli have been fairly well studied, the neural mechanisms underlying visually-induced illusory touch remain unclear. This study investigated whether illusory tactile perception engages the somatosensory cortex in a manner similar to veridical touch. Twenty healthy adults participated in an event-related functional magnetic resonance imaging (fMRI) study while performing a tactile numerosity judgment task. Each trial …

Less Self, Less Fear: Manipulation Of The Self Using Virtual Out-Of-Body Experiences To Alter The Conscious And Unconscious Experience Of Emotion, Dillon Freed

Dissertations, Theses, and Capstone Projects

This study investigated whether adopting an out-of-body perspective in virtual reality (VR) reduces subjective and physiological emotional responses to vicarious pain stimuli compared to inhabiting a first-person embodied avatar. Twenty-four participants experienced two counterbalanced VR conditions: (1) Avatar Embodiment (AV), in which they inhabited a photorealistic avatar from a first-person perspective, and (2) a Virtual Out-of-Body Experience (vOBE), in which they observed their avatar from a displaced third-person perspective. In both conditions, participants viewed a standardized series of vicarious pain images while electrodermal activity was recorded and self-report measures of embodiment (AV) and disembodiment (the vOBE state), emotional intensity (a …

An Impact Assessment Of The Effectiveness Of Utilizing Informal Health Communication Interventions To Spread Health Recommendations And Change Public Perception, Lina Mohamed Ezzat Ahmed Abdel Mawgoud

Theses and Dissertations

Brain health is an increasingly urgent but critically under-addressed public health priority in Egypt and the wider MENA region. Despite its centrality to aging, productivity, and overall quality of life, public understanding of brain health remains limited, and stigma continues to shape responses to dementia and cognitive decline. This study evaluates the effectiveness of informal, culturally adapted health communication as a tool to shift perception, increase awareness, and promote behavior change among non-medically trained adults in Egypt.

Grounded in global evidence on cognitive reserve, neuroplasticity, and the life-course approach to brain health, the intervention translated expert-informed brain health recommendations into …

Brain Gains: A Review Of Remediation Treatment Strategies Using Exercise Following Traumatic Brain Injury, Jessica Smith, Kristin Biggins, Loriann Helgeson

The Open Journal of Occupational Therapy

In this Opinions in the Profession article, we explore remediation treatment strategies using exercise for recovery from post-traumatic brain injury and aim to justify the use of such treatment in the occupational therapy profession to increase skills for functional gain. Common treatment strategies used by occupational therapists after brain injury are compensatory strategies, indicating the client learns a new way to perform the task. Though effective, it is also necessary to consider how remediation and neuroplasticity are essential. Teaching new approaches to complete tasks results in functional gains; however, focusing on foundational skills using exercises to relearn motor patterns to …