Periodontics and Periodontology Commons^™

Clinical Outcomes Of Adjunctive Use Of Oxygen-Releasing Formula In Non-Surgical Treatment Of Periodontal Abscess Associated With Type 2 Diabetes Mellitus, Anil Kumar Kanakamedala, Laxmi Kavya Gangireddy, Gautami S Penmetsa, Sruthima Gottumukkala, Mohan Kumar Pasupuleti, Konathala Santhosh Venkata Ramesh

Journal of Dentistry Indonesia

Background: This study aimed to evaluate the effectiveness of oxygen-releasing formula (ORF) as an adjunct in the non-surgical management of periodontal abscess in patients with type 2 diabetes mellitus.

Methods: This split-mouth clinical trial was conducted on 14 patients with periodontal abscess with type 2 diabetes mellitus (T2DM), who were divided into a control group, nonsurgical periodontal therapy (NSPT) alone, and a test group (NSPT+ORF). Parameters such as Landry's healing index (HI) were evaluated at 1 week, 2 weeks, and 1 month. Probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing presence or absence (BOP) …

Adverse Drug Reaction Reporting In Dental Practice And The Importance Of Pharmacovigilance In Dental Education, Radhakrishna Lagishetty, Lakshmi Ramya T, Kvr Barath Raju, Mohan Kumar Pasupuleti

Journal of Dentistry Indonesia

Background: Adverse drug reactions (ADRs) are a critical component of patient safety; however, ADR monitoring remains underutilized in dentistry. This study aimed to assess knowledge, attitudes, and practices regarding ADR reporting among undergraduate and postgraduate students and practicing dentists.

Methods: A cross-sectional observational study was conducted using a structured, validated 19-item questionnaire covering socio-demographics, knowledge (6 items), attitude (4 items), and practice (5 items), which was distributed both in person and online. A total of 258 complete responses were analyzed out of 300 individuals contacted (response rate: 86%). Descriptive statistics and Chi-square tests were applied, with p < 0.05 considered statistically significant.

Results …

Investigation Of Patients' Use Of Non-Pharmacological Substances In Dental Pain Management, Neslihan Yılmaz Çırakoğlu, Özgenur Kaya

Journal of Dentistry Indonesia

Background: Dental pain is a complex condition influenced by biological, biochemical, environmental, and psychological factors. Before seeking professional care, many patients attempt to relieve dental pain using self-administered, non-medical agents. This study aimed to investigate patients’ use of non-pharmacological substances in dental pain management and to identify factors influencing these practices.

Methods: The questionnaire consisted of four sections addressing demographic characteristics, oral hygiene habits, pain characteristics, and pain-relief agents. Categorical variables were analyzed using Pearson’s chi-square test. Categorical data are presented as frequencies and percentages, while continuous data are expressed as mean ± standard deviation and median values. …

Orthodontic Camouflage Treatment Of A Severe Class Iii Skeletal Pattern With Anterior Open Bite: A Case Report, Dikeledi Maureen Letsholo, Mandla Dominic Nyakale, Mosimane Peter Silas Sethusa

Journal of Dentistry Indonesia

Background: Class III malocclusion combined with anterior open bite (AOB) is one of the most challenging occlusal problems to treat. The objective of this article was to report a case of an adult female patient diagnosed with Class III malocclusion combined with an anterior open bite and a hyperdivergent facial pattern.

Case Report: Camouflage orthodontic treatment with the extraction of maxillary and mandibular first premolars was used to treat the patient. Anterior teeth were retracted maximally against the Nance holding arch and fixed lingual arch appliances, and box elastics were used to close AOB. At the end of …

Evaluation Of Optimal Force For Intrusion Of A Periodontally Compromised Maxillary Anterior Dentition Treated With Fixed Orthodontics – A Finite Element Analysis, Tanzim Ahmed, Amrita Puri, Aatira Nair, Anshul Singla, Mathew Koshy Vaidyan, Shruti Sharma, Chhavi Singh

International Arab Journal of Dentistry

Introduction: Adult orthodontic treatment is increasingly sought due to aesthetic and functional concerns, often involving periodontally compromised patients with altered biomechanics. Reduced bone support shifts the center of resistance and necessitates lower, carefully controlled forces, while finite element modeling has become a key tool to analyze tissue response under such conditions.

Objectives: The study aimed to determine the optimal intrusive force for periodontally compromised maxillary anterior teeth using Finite Element Analysis (FEA).

Methods: A 3D finite element model of the maxillary anterior dentition was created and divided into healthy and compromised halves, the latter with one-third alveolar bone loss. A …

Comparative Evaluation Of A-Prf+ Or Collagen Membrane On Hard And Soft Tissue Changes Following Immediate Implant Placement: A Randomized Clinical Trial, Raagul S, Rahul Chopra, Sumit Malhotra, Prashansa Sharma, Ankur Tyagi, Nancy Singh

International Arab Journal of Dentistry

Objectives: To evaluate and compare clinical and radiographic parameters viz. Gingival Index (GI), Plaque Index (PI), Width of Keratinized Tissue (WKT), Midbuccal & Midlingual/Midpalatal soft tissue thickness (STT), ISQ values and crestal bone levels (CBL) using CBCT at baseline and 6 months in Group I (Immediate implant placement & A-PRF+) and Group II (Immediate implant placement & Collagen Membrane).

Methods: A total of 20 sites indicated for extraction were selected and randomly divided into: GROUP I : 10 sites were treated with immediate implant placement and covered with an A-PRF+ membrane and GROUP II : 10 sites were treated with …

Predictive Analysis For Success And Complications In Dental Implant Therapy Using Artificial Intelligence Models, Vishnu Priya Veeraraghavan, Aysha Jebin A, Isha Dusane, Govind Baheti, Ankita Agarwal, Santosh R Patil

International Arab Journal of Dentistry

Introduction: Dental implant therapy is a predictable treatment for tooth replacement, but its success is influenced by multiple patient, surgical, and systemic factors. Traditional statistical models, such as logistic regression, are limited in capturing nonlinear relationships among these variables. Artificial intelligence (AI) can integrate diverse predictors to enhance clinical risk assessment and improve treatment outcomes.

Objective: To identify key predictors of dental implant success and develop AI-based models capable of accurately forecasting implant outcomes using clinical and surgical parameters.

Methods: This retrospective cohort study analyzed data from 172 patients (219 implants) placed between 2020 and 2021. Patient demographics, systemic health …

Can Gingival Crevicular Fluid Help In Diagnosing Pulp Inflammation? A Systematic Review, Wael Kassamany, Roula Abiad

BAU Journal - Science and Technology

This review aims to find if there’s a positive correlation between biological markers detected in human gingival crevicular fluid and pulp inflammation.

An electronic search of three databases; PubMed, EBSCOhost and Google Scholar was conducted using the keywords “tooth or teeth or pulp” AND “gingival crevice fluid or gingival crevicular fluid” for English articles published between the year 1990 and 2026. Information regarding study design, patients age range and gender distribution, sampling method used, types of biomarkers studied, assay test used, and key findings of each article were extracted and analyzed.

Biomarkers studied were substance P “SP”, neurokinin A “NKA”, …

In Silico Model Of Musa Acuminata Stem As An Anticancer On Oral Squamous Cell Carcinoma Against Egfr, Nevrila Dewi Rachmayani, Amy Nindia Carabelly, I Wayan Arya Krishnawan Firdaus, Maharani Laillyza Apriasari, Juliyatin Putri Utami

Journal of Dentistry Indonesia

Background: Oral squamous cell carcinoma (OSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR). Citral, eucalyptol, and caffeic acid phenethyl ester (CAPE), which are derived from Musa acuminata, have shown anticancer activity. This study evaluated the potential of citral, eucalyptol, and CAPE from Musa acuminata as anticancer agents for OSCC by targeting EGFR using an in silico approach.

Methods: Potential biological activity was predicted using Prediction of Activity Spectra for Substances (PASS) Online. Molecular docking was conducted with AutoDock Vina, and BIOVIA Discovery Studio was used to analyze binding affinity, interaction types, and bond …

Micro-Ct Evaluation Of Root Canal Transportation And Centering Ability In Mesial Canals Of Mandibular First Molars, Selen Ince Yusufoglu, Esma Saricam, Mert Ocak, Ferhat Geneci, Burak Bilecenoğlu

Journal of Dentistry Indonesia

Background: This study aimed to evaluate canal transportation, centering ability, structure model index (SMI), surface area, and root canal volume changes in the mesial canals of mandibular first molars using micro-CT.

Methods: Twenty-four mandibular first molars with two separate mesial canals and moderate curvature were included. Teeth were scanned using micro-CT before instrumentation and randomly divided into three groups (N = 8). Root canals were prepared using OneShape, OneCurve, and Rotate file systems, followed by post-instrumentation micro-CT scanning (10µm/pixel resolution). Changes in canal volume, surface area, transportation, centering ability, and SMI were analyzed at the apical, middle, and …

Evaluation Of An Audiovisual Educational Tool With Reinforcement Messages For Orthodontic Patients: A 6-Month Randomized Controlled Trial, Laura Restrepo Quijano, Maria Paula Vasco Gomez, Natalia Hurtado Velasquez, Luis Fabian Benitez Moreno

Journal of Dentistry Indonesia

Background: Orthodontic treatment increases the risk of bacterial plaque accumulation; therefore, oral hygiene education is essential to prevent complications, but its impact is usually limited when it is not reinforced with effective tools. This study aims to evaluate an audiovisual educational tool with reinforcement messages, compared with a verbal explanation about the proper use of the orthodontic oral hygiene kit.

Methods: This was a randomized controlled trial that included 62 patients randomly assigned to an intervention group: 31 patients who received an educational video plus three reinforcement messages via WhatsApp, and a control group: 31 patients who received …

Sinus Formation As A Manifestation Of Chronic Periodontitis In Mandibular Anterior Region: A Report On 2 Cases, Anisha Kumari, Shikha Tewari

Journal of Dentistry Indonesia

Background: Periodontitis is defined as an inflammatory disease of the supporting tissues of the teeth caused by specific microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone. Clinical manifestations of Persistent chronic periodontitis may mimic varied clinical manifestations, including those of apical abscess and systemic involvement.

Case report: This report presents the management of an intraoral sinus mimicking a chronic apical abscess in the mandibular anterior region associated with deep periodontal pockets in two male patients in their early thirties. With careful clinical and radiological examination and ruling out of endodontic and systemic involvement, the …

Therapeutic Potential Of Bacillus Coagulans Unique Is2 Probiotic Supplementation On Early Periodontitis Patients: A Randomized Controlled Trial, Renu Gaur, Aysha Jebin A, Prabhuji M L V

International Arab Journal of Dentistry

Objectives: Bacillus coagulans (B. coagulans) is a probiotic commonly used for broad spectrum of systemic infections, its potential to treat oral infections, particularly periodontitis, is still being studied.The aim of the study was to evaluate the efficacy of probiotic B. coagulans as an adjunct to SRP in periodontitis patients.

Methods: Thirty systemically healthy patients with stage I/ stage II and grade A/ grade B periodontitis were selected and randomly divided into two groups. The control group received SRP along with placebo and the test group received SRP + B. coagulans probiotic chewable tablets. At baseline, one month, and three months …

Laser-Assisted New Attachment Procedure: A Review, Divya Khanna B.D.S., M.D.S.

The New York State Dental Journal

Periodontal treatment modalities have evolved substantially to evidence-based minimally invasive treatment options. Lasers have proved to be an effective tool by providing a myriad of benefits and advantages while eliminating many of the negative sequelae that have been historically associated with conventional pocket elimination surgery. Laser-assisted new attachment procedure (LANAP) is a well-defined treatment protocol that has been validated with human histology and has demonstrated both short- and long-term success. LANAP has proven to be an effective, safe and predictable treatment option for achieving regeneration and new attachment formation, leading to favorable clinical outcomes, improved patient compliance and acceptability.

Periodontal Biomarkers In Cardiovascular Disease: Mechanisms, Diagnostics, And Clinical Implications, Max Foroughi, Keykavous Parang

Pharmacy Faculty Articles and Research

Purpose

Periodontal disease is a chronic inflammatory condition increasingly associated with cardiovascular disease (CVD) beyond shared risk factors. This review evaluates evidence linking periodontal inflammation to cardiovascular outcomes and identifies periodontal biomarkers with potential relevance for cardiovascular risk assessment.

Methods

A narrative review was conducted using PubMed, Scopus, and Web of Science databases, including studies published between 1990 and 2025. Epidemiological, clinical, and mechanistic studies examining associations between periodontal disease, inflammatory and microbial biomarkers, and cardiovascular outcomes were included. Biomarkers were categorized as inflammatory cytokines, acute-phase proteins, oxidative stress markers, lipid mediators, and microbial indicators. Evidence regarding periodontal therapy and …

Pebbly Gingival Nodule In An Older Male, Victoria L. Scarpa D.D.S., M.S., Yussra O. Mahmud M.P.H., B.S., Daria Vasilyeva D.D.S., Ph.D.

The New York State Dental Journal

We herein present a case of a giant cell fibroma in an older adult male that clinically has a pebbly or bosselated surface architecture, mimicking a squamous papilloma. The giant cell fibroma is a fibrous tumor distinct from the common irritation fibroma and may easily be mistaken for a papilloma based on clinical features. This case is reported to provide diagnostic value to the general practitioner.

Nicotine's Influence On The Oral Microbiome: Harm Reduction Or Hidden Risk?, Trevor Ward, Kamran Awan

Annual Research Symposium

No abstract provided.

Ai Applications In Assessing Risk For Periodontal Disease: A Systematic Review, Grant O. Korte, Claudia M. Tellez Freitas

Annual Research Symposium

Objectives:

The goal of this systematic review is to examine the impact of using artificial intelligence (AI) to predict a patient’s risk level for periodontal disease by analyzing proven systemic health diseases linked to periodontitis. This is being done by primarily focusing on prevention and early diagnosis using machine learning programs that have been proven effective in other fields of periodontitis research.

Methods:

To conduct this study, a comprehensive literature review of journals published after 2020 was performed through four databases: PubMed, Scopus, Web of Science and Dentistry and Oral Science Source. The search was completed in adherence …

Artificial Intelligence Versus Human Dental Expertise In Diagnosing Periapical Pathosis On Periapical Radiographs: A Multicenter Study, Fatma E.A Hassanen, Radwa R. Hussein, Mohamed Riad Elgarhy, Shaymaa Mohamed Maher, Marwa Ezz, Ahmed Hassen, Sherif Heidar, Amr Edress, Asmaa Abou-Bakr

Dentistry

Periapical pathosis in periapical radiographs must be properly diagnosed for the success of endodontic treatment but is often muddled by 2D imaging limitations and subjective interpretation. Artificial intelligence (AI) offers a solution, but whether the diagnostic granularity of AI versus human clinicians in everyday clinical practice has been adequately explored remains to be addressed. The purpose of this study was to evaluate the diagnostic accuracy of ChatGPT-5 in detecting periapical radiographic abnormalities compared with the three-expert consensus reference standard. Methods: In this diagnostic accuracy retrospective study, 270 periapical radiographs were independently read by a large language model (ChatGPT-5) and a …

Could Dietary Zinc Protect Your Gums? Insights From Non-Diabetic Adults, Jacob R. Kelly, Hayden Dehoyos, Man Hung Phd, Amir Mohajeri Phd

Annual Research Symposium

Background:
Zinc plays an important role in enzymatic and inflammatory processes that may influence periodontal health. The relationship between zinc intake and periodontitis remains insufficiently characterized in adults without diabetes.
Methods:
A population-based adult sample was analyzed to examine the association between zinc intake from dietary and supplemental sources and periodontal disease, adjusting for relevant demographic, socioeconomic, behavioral, and health-related factors.
Results:
Zinc intake patterns varied across population subgroups and were associated with periodontal outcomes after accounting for potential confounders. Adequate zinc intake was consistently linked to more favorable periodontal status.
Conclusion:
These findings suggest that sufficient zinc intake may …