Computer Sciences Commons^™

Hyperpolarized Magnetic Resonance Imaging, Nuclear Magnetic Resonance Metabolomics, And Artificial Intelligence To Interrogate The Metabolic Evolution Of Glioblastoma, Kang Lin Hsieh, Qing Chen, Travis C Salzillo, Jian Zhang, Xiaoqian Jiang, Pratip K Bhattacharya, Shyan Shams

Faculty, Staff and Student Publications

Glioblastoma (GBM) is a malignant Grade VI cancer type with a median survival duration of only 8-16 months. Earlier detection of GBM could enable more effective treatment. Hyperpolarized magnetic resonance spectroscopy (HPMRS) could detect GBM earlier than conventional anatomical MRI in glioblastoma murine models. We further investigated whether artificial intelligence (A.I.) could detect GBM earlier than HPMRS. We developed a deep learning model that combines multiple modalities of cancer data to predict tumor progression, assess treatment effects, and to reconstruct in vivo metabolomic information from ex vivo data. Our model can detect GBM progression two weeks earlier than conventional MRIs …

In Reply: Can Artificial Intelligence Make The Cut? Dissecting Large Language Model’S Surgical Exam Performance, Adam M. Ostrovsky, Joshua R. Chen, Vishal N. Shah, Babak Abai

Department of Surgery Faculty Papers

No abstract provided.

Extending Segment Tree For Polygon Clipping And Parallelizing Using Openmp And Openacc Compiler Directives, M. K. Buddhi Ashan, Satish Puri, Sushil K. Prasad

Computer Science Faculty Research & Creative Works

A segment tree is a versatile tree-based data structure over intervals or line segments efficiently supporting several computational operations such as stabbing query, segment arrangement, and planar point location, both theoretically and practically. Polygon clipping is a basic operation in domains such as Computer Graphics, Computer-aided Design, and Geographic Information Science (GIS). Given two polygons with n vertices, polygon clipping algorithms find the geometric intersection or union in O(n2) time using Foster's all-to-all edge intersection testing and O((n + k) logn) time using Vatti's sweep line-based method, where k is the number of intersections. No known segment tree implementation, including …

Groundwater Modeling Of The Ogallala Aquifer: Use Of Machine Learning For Model Parameterization And Sustainability Assessment, Tewodros Aboret Tilahun

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Addressing groundwater depletion problems in heterogeneous aquifer systems is a challenge. The heterogeneous Ogallala Aquifer, a critical source of groundwater in the central United States, has undergone decades of decline in water levels due to pumping. This project aims to build a robust groundwater model to evaluate optimal scenarios for sustainable use of the groundwater resource within a section of the Ogallala aquifer located in the Middle Republican Natural Resources District (MRNRD). This study follows a comprehensive approach involving parameterization, construction, and optimization. The model is parametrized using hydraulic conductivity and recharge values obtained from a random forest-based machine learning …

Mixed Criticality Multicore Compositional Framework, Amjad Ali, Shahid Iqbal, Imran Taj, Muhammad Fayaz, Asad Masood Khattak, Bashir Hayat

All Works

In the field of real-time systems, component-based models for mixed criticality systems (MCS) on multicore platform are gaining significant attention of the researchers from the recent past. The concept of mixed-criticality is firstly applied on single core systems but after gaining attention, it evolved to multicore platform. Initially, the tasks of MCS executes in low mode however if a task having high criticality does not its scheduling requirements complete its low mode, then the system switch to high mode. In high mode, only high critical tasks executes its high mode scheduling requirements, while all low tasks are discarded from further …

Open-Source Forensics Tools Are Great Tools For Critical Used Machines, Erik Herrera

Electronic Theses and Dissertations

Open-Source software exists on everything from operating systems to daily productivity applications. In digital forensics, a very popular tool that is used to learn on and expand is Autopsy. Autopsy is known in the digital world due to its potential and wide usage. It is in many built packages of software inside the open-source world of applications. It is built into premade operating systems that are involved in Digital Forensics and Penetration Testing. Prebuilt OS includes Kali Linux and Computer Aided Investigative Environment (CAINE).

In the application to defend Open-Source software being just as good as closed-source software, I will …

Digital Scribes: A Possible Solution For Provider Burnout By Reducing Provider Workload, Shannon Storley

Theses and Graduate Projects

Background: Provider burnout is continuing to be a massive problem for our healthcare industry. One major contributor to provider burnout is burdensome administrative tasks associated with documentation of electronic medical records (EMR). This review aims to uncover the applications for artificially intelligent digital scribes as a solution to reduce EMR documentation burden. Purpose: Provider burnout has shown to increase the incidence of major mistakes and decreased patient safety grades. Digital scribes could be a solution in reducing provider burnout by reducing the administrative burden of EMR documentation. Methods: A comprehensive literature review was conducted using articles from PubMed using search …

Analyzing The Usability, Performance, And Cost-Efficiency Of Deploying Ml Models On Various Cloud Computing Platforms, Hongyu Wang

Masters Theses (Archived)

With the enhanced computing capabilities and accessibility to cloud resources, major cloud computing providers such as Google Cloud Platform (GCP), Amazon Web Services (AWS), and Microsoft Azure offer Machine Learning (ML) and AI services. Their primary purpose is to provide efficiency, scalability, and adaptability in modern software development and IT operations while reducing overall costs and operational complexity. However, prospective customers of the services often question which ML-AI service will best suit their organizational and business needs. This study compares and analyzes the usability, performance, and cost-efficiency of deploying Machine Learning (ML) models across three cloud platforms: GCP, AWS, and …

Deep-Learning Approaches To Predict Remaining Useful Life Of Hard Disks, Rohan Mohapatra

Master's Theses

On a daily basis, data centers process huge volumes of data using inexpensive hard disks. Data stored in these disks serve a range of critical functional needs from financial, and healthcare to aerospace. As such, premature disk failure and consequent loss of data can be catastrophic. To mitigate the risk of failures, cloud storage providers perform condition-based monitoring and replace hard disks before they fail. By estimating the remaining useful life (RUL) of hard disk drives, one can predict the time-to-failure of a particular device and replace it at the right time, ensuring maximum utilization whilst reducing operational costs. We …

Ethical Challenges And Solutions Of Generative Ai: An Interdisciplinary Perspective, Mousa Al-Kfairy, Dheya Mostafa, Nir Kshetri, Mazen Insiew, Omar Alfandi

All Works

This paper conducts a systematic review and interdisciplinary analysis of the ethical challenges of generative AI technologies (N = 37), highlighting significant concerns such as privacy, data protection, copyright infringement, misinformation, biases, and societal inequalities. The ability of generative AI to produce convincing deepfakes and synthetic media, which threaten the foundations of truth, trust, and democratic values, exacerbates these problems. The paper combines perspectives from various disciplines, including education, media, and healthcare, underscoring the need for AI systems that promote equity and do not perpetuate social inequalities. It advocates for a proactive approach to the ethical development of AI, emphasizing …

Origin, Regulation, And Function Of Bone Marrow Adipose Tissue And Implications For Bone Health, Xiao Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Bone marrow adipose tissue (BMAT) is a unique fat depot located within the skeletal system that takes up a large portion of the total bone marrow volume and contains tremendous amounts of energy that can be potentially utilized to fuel the body. However, largely attributed to its strong resistance to lipolytic stimuli and its persistent accumulation in various physiological and pathological conditions, the exact function of BMAT within the bone and how it is regulated throughout the body remains largely unclear. This dissertation sought to better understand the unique role of BMAT within the bone marrow niche by first reviewing …

Modular Approach To Soft Mobile Robots, Dimuthu Kodippili Arachchige

College of Computing and Digital Media Dissertations

Soft robot locomotion is a highly promising but under-researched subfield within the field of soft robotics. The compliant limbs and bodies of soft robots offer numerous benefits, including the ability to regulate impacts, tolerate falls, and navigate through tight spaces. These robots have the potential to be used for various applications, such as search and rescue, inspection, surveillance, and more. The state-of-the-art still faces many challenges, including limited degrees of freedom, a lack of diversity in gait trajectories, insufficient limb dexterity, limited payload capabilities, lack of control methods, etc. To address these challenges, this research introduces a modular approach to …

Ai-Based Methods For Detecting And Classifying Age-Related Macular Degeneration: A Comprehensive Review, Niveen Nasr El-Den, Mohamed Elsharkawy, Ibrahim Saleh, Mohammed Ghazal, Ashraf Khalil, Mohammad Z. Haq, Ashraf Sewelam, Hani Mahdi, Ayman El-Baz

All Works

This paper explores the advancements and achievements of artificial intelligence (AI) in computer vision (CV), particularly in the context of diagnosing and grading age-related macular degeneration (AMD), one of the most common leading causes of blindness and low vision that impact millions of patients globally. Integrating AI in biomedical engineering and healthcare has significantly enhanced the understanding and development of the CV application to mimic human problem-solving abilities. By leveraging AI-based models, ophthalmologists can improve the accuracy and speed of disease diagnosis, enabling early treatment and mitigating the severity of the conditions. This paper presents a comprehensive analysis of many …

A Fair Ontology For Aps Beamline Experiments, Gabriel Ponón, Balashanmuga Priyan Rajamohan, Mohommad Redad Mehdi, Finley Holt, Erika Barcelos, Pawan K. Tripathi, Roger H. French

Student Scholarship

Data produced at the 1-ID beamline APS are often serialized in large, disconnected tables, which can impede the effective reuse and replication of analysis performed for cutting edge research and instrumentation conducted at the facility. This poster describes an alternative approach of utilizing component-based FAIR (Findable, Accessible, Interoperable, and Reusable) ontologies as a framework for organizing and connecting experimental variables. Three packages were developed to facilitate the creation and connection of component ontologies into a fully connected FAIR ontology for an experiment. An ontology-based workflow is also discussed for beamline scientists and users to visualize and connect collected values alongside …

Knowledge Management And Semantic Reasoning: Ontology And Information Theory Enable The Construction Of Knowledge Bases And Knowledge Graphs, Quynh D. Tran, Ozan Dernek, Erika I. Barcelos, Laura S. Bruckman, Roger H. French

Researchers, Instructors, & Staff Scholarship

FAIR (Findable, Accessible, Interoperable, Reusable) principles are guidelines Wilkinson, et. al. (2016) proposed for data governance and stewardship. Ontology is a powerful tool that can achieve many aspects of all four FAIR principles. Unfortunately, there is a misconception about ontology that it is only useful for establishing FAIR data. We need to think beyond data to answer the question “So what?” after an ontology is developed. It is critical to apply FAIR principles to results, analysis, and models, which is where the concept of digital thread comes in. FAIRified results, analysis, and models can be stored in a knowledge base …

Enhancing Clinical Relevance Of Pretrained Language Models Through Integration Of External Knowledge: Case Study On Cardiovascular Diagnosis From Electronic Health Records, Qiuhao Lu, Andrew Wen, Thien Nguyen, Hongfang Liu

Faculty, Staff and Student Publications

Background: Despite their growing use in health care, pretrained language models (PLMs) often lack clinical relevance due to insufficient domain expertise and poor interpretability. A key strategy to overcome these challenges is integrating external knowledge into PLMs, enhancing their adaptability and clinical usefulness. Current biomedical knowledge graphs like UMLS (Unified Medical Language System), SNOMED CT (Systematized Medical Nomenclature for Medicine-Clinical Terminology), and HPO (Human Phenotype Ontology), while comprehensive, fail to effectively connect general biomedical knowledge with physician insights. There is an equally important need for a model that integrates diverse knowledge in a way that is both unified and compartmentalized. …

Application Of Machine Learning For Multi-Omics Data Integration, Dhoha Abid

McKelvey School of Engineering Graduate Student Theses & Dissertations

Traditionally, machine learning (ML) is used to train a model to predict scores for instances that were not seen by the model during training. In this conventional use of ML, the model is trained to learn general patterns that relate features to labels, so it can predict accurate scores for unseen data. Here, we use ML, unconventionally, to integrate different types of noisy data. Specifically, for biological investigations, in which there is no mean to measure a ground truth. We propose to train a ML model to predict scores on the same instances that were used in its training. In …

On Q^*-Closed Sets In Fuzzy Neutrosophic Τopology: Principles, Proofs, And Examples, Hajar Y. Mohammed, Fatimah M. Mohammed, Ghada Al-Mahbashi

Neutrosophic Systems with Applications

This paper aims to present a new concept of sets known as fuzzy neutrosophic Q^*-closed sets in fuzzy neutrosophic topology. In this study, we explore and investigate more novel properties of these classes by some new definitions, theorems, and propositions. Therefore, a group of examples is presented and discussed to clarify the relationships between the new study of Q^*-closed sets with other sets.

On Q^*-Closed Sets In Fuzzy Neutrosophic Τopology: Principles, Proofs, And Examples, Hajar Y. Mohammed, Fatimah M. Mohammed, Ghada Al-Mahbashi

Neutrosophic Systems with Applications

This paper aims to present a new concept of sets known as fuzzy neutrosophic Q^*-closed sets in fuzzy neutrosophic topology. In this study, we explore and investigate more novel properties of these classes by some new definitions, theorems, and propositions. Therefore, a group of examples is presented and discussed to clarify the relationships between the new study of Q^*-closed sets with other sets.

Normed-Bifuzzy Valued-Ideals Of Semigroups, Mohammad Hamidi, Rasul Rasuli

Neutrosophic Systems with Applications

As concerning the views of T norms and T conorms, the intent of article is to define and probe the fuzzy semigroups, fuzzy ideals, fuzzy bi-ideals, bifuzzy subsemigroups, bifuzzy ideals, bifuzzy bi-ideals, fuzzy (1, 2)-ideals and bifuzzy (1, 2)-ideals in any given semigroup. Also, we indicate and study their basic properties of them in completely regular semigroups. Finally, we extend these concepts and so characterize (pre)image of them in semigroup homomorphisms.

Reless: A Framework For Assessing Safety In Deep Learning Systems, Nan Jia, Anita Raja, Raffi T. Khatchadourian

Publications and Research

Traditionally, software refactoring helps to improve a system's internal structure and enhance its non-functional features, such as reliability and run-time performance, while preserving external behavior including original program semantics. However, in the context of learning-enabled software systems (LESS), e.g., Machine Learning (ML) systems, it is unclear which portions of a software's semantics require preservation at the development phase. This is mainly because (a) the behavior of the LESS is not defined until run-time; and (b) the inherently iterative and non-deterministic nature of ML algorithms. Consequently, there is a knowledge gap in what refactoring truly means in the context of LESS …

Normed-Bifuzzy Valued-Ideals Of Semigroups, Mohammad Hamidi, Rasul Rasuli

Neutrosophic Systems with Applications

As concerning the views of T norms and T conorms, the intent of article is to define and probe the fuzzy semigroups, fuzzy ideals, fuzzy bi-ideals, bifuzzy subsemigroups, bifuzzy ideals, bifuzzy bi-ideals, fuzzy (1, 2)-ideals and bifuzzy (1, 2)-ideals in any given semigroup. Also, we indicate and study their basic properties of them in completely regular semigroups. Finally, we extend these concepts and so characterize (pre)image of them in semigroup homomorphisms.

Mapping Urban Tree Canopy Using Publicly Available Satellite Data, Rosemary Mcguinness

Theses and Dissertations

This project addresses the need for accessible, cost-effective tools for quantifying spatial and temporal changes in tree canopy cover in urban areas. Urban tree canopy provides a wide range of ecosystem services, including lowering air temperatures, reducing pollution, and mitigating stormwater runoff. Cities around the world have placed the expansion of their urban forests at the center of their sustainability goals. Consistent and timely data on urban tree canopy is essential for urban greening initiatives to succeed. Existing methods of accessing information about urban tree canopy are highly technical, costly, and labor-intensive, while the freely available source of tree canopy …

Development And Optimization Of A 1-Dimensional Convolutional Neural Network-Based Keyword Spotting Model For Fpga Acceleration, Trysten E. Dembeck

Masters Theses

Spoken Keyword Spotting (KWS) has steadily remained one of the most studied and implemented technologies in human-facing artificially intelligent systems and has enabled them to detect specific keywords in utterances. Modern machine learning models, such as the variants of deep neural networks, have significantly improved the performance and accuracy of these systems over other rudimentary techniques. However, they often demand substantial computational resources, use large parameter spaces, and introduce latencies that limit their real-time applicability and offline use. These speed and memory requirements have become a tremendous problem where faster and more efficient KWS methods dominate and better meet industry …

Medical Image Analysis Based On Graph Machine Learning And Variational Methods, Sina Mohammadi

Computational and Data Sciences (PhD) Dissertations

This study explores advanced methodologies for enhancing brain tumor segmentation, addressing the complexity and diversity of tumor sub-regions in medical imaging. We introduce a novel approach utilizing Graph Neural Networks (GNNs) that incorporate both spectral and spatial insights for segmentation. By leveraging various supervoxel creation methods such as VCCS, SLIC, Watershed, Meanshift, and Felzenszwalb-Huttenlocher, we structured 3D MRI images into a graph format. This format enabled the implementation of Spectral and Spatial GNNs to capture comprehensive local and global tumor characteristics effectively. Our Spectral-Spatial GNN model, integrating the Laplacian matrix, demonstrated significant improvements in segmenting distinct tumor sub-regions of Necrosis, …

What If The Resulting Interval Is Too Wide: From A Heuristic Fuzzy-Technique Idea To A Mathematically Justified Approach, Marc Fina, Vladik Kreinovich

Departmental Technical Reports (CS)

In engineering designs, we usually need to make sure that the values of some characteristics y do not exceed a certain threshold y0 – e.g., that the stress at each location does not exceed a certain critical value. Usually, we know how each of these characteristics y depends on the design parameters x1, . . . ,xn, i.e., we know the function y= f (x1, . . . ,xn). However, it is not enough to use the nominal values of the design parameters in our analysis, since the actual values are, in general, somewhat different from the nominal values. Often, …

An Efficient Neutrosophic Approach For Evaluating Possible Industry 5.0 Enablers In Consumer Electronics: A Case Study, Mai Mohamed, Asmaa Elsayed, Bilal Arain, Jun Ye

Neutrosophic Systems with Applications

With the use of cutting-edge technologies like artificial intelligence (AI), robotics, and the Internet of Things (IoT), Industry 5.0 represents a breakthrough move towards a sustainable and human-centered industrial future. Industry 5.0 endeavors to transform industries such as consumer electronics by emphasizing sustainability and collaboration, in contrast to its predecessors, who only concentrated on automation and efficiency. Along with improved manufacturing efficiency and product innovation, this change in the consumer electronics sector also redefines the human-machine interaction. This paper proposes a novel hybrid integrating model that combines the Entropy Weight Method (EWM), Best-Worst Method (BWM), and an acronym in Portuguese …

Cubic Soft Ideals On B-Algebra For Solving Complex Problems: Trend Analysis, Proofs, Improvements, And Applications, Muhammad Saeed, Hafiz Inam Ul Haq, Mubashir Ali

Neutrosophic Systems with Applications

In this paper, we introduce the concepts of cubic soft (CS) algebra, CS o-subalgebra, and CS ideals within the framework of B-algebra. We provide comprehensive characterizations of these new structures, elucidating their unique properties and interrelationships. Specifically, we present detailed conditions under which a CS subalgebra can be classified as a closed CS ideal. Our analysis explores the intricate relationships among closed cubic soft ideals, cubic soft subalgebras, and cubic soft o-subalgebras. By doing so, we aim to provide a deeper understanding of how these structures interact and coexist within the broader context of B-algebra The findings offer significant insights …

Divergence Measures And Aggregation Operators For Single-Valued Neutrosophic Sets With Applications In Decision-Making Problems, Surender Singh, Sonam Sharma

Neutrosophic Systems with Applications

Single-valued neutrosophic sets (SVNSs) facilitate the representation of uncertain information more extensively than conventional methods. The study of divergence measures of SVNSs is important due to their applications in different areas like multi-criteria decision-making (MCDM), pattern recognition, cluster analysis, machine learning, etc., In this paper, we introduce a divergence measure for SVNSs. The suggested divergence measure is applied to cluster analysis for the classification of imprecise data. For establishing the reasonability and advantage of the suggested divergence measure in a clustering problem over the existing measures, a comparative assessment is also presented. Furthermore, we introduce, an inferior ratio method for …

Feature Importance In The Context Of Traditional And Just-In-Time Software Defect Prediction Models, Susmita Haldar, Luiz Fernando Capretz

Electrical and Computer Engineering Publications

Software defect prediction models can assist software testing initiatives by prioritizing testing error-prone modules. In recent years, in addition to the traditional defect prediction model approach of predicting defects from class, modules, etc., Just-In- Time defect prediction research, which focuses on the change history of software products is getting prominent. For building these defect prediction models, it is important to understand which features are primary contributors to these classifiers. This study considered developing defect prediction models incorporating the traditional and the Just-In-Time approaches from the publicly available dataset of the Apache Camel project. A multi-layer deep learning algorithm was applied …