Physical Sciences and Mathematics Commons^™

Florida Science: The Science That Makes Florida Different, Terence W. Cavanaugh

Secondary Level Resources

This book was created to assist students with their understanding of how science occurs in Florida. When teaching science or any subject it’s important to remember to begin with the concrete and then move to the abstract. I have found that it has helped my students when I begin by teaching science concepts in a concrete manner and expand from there. For example, when I taught about topographic maps, the students were much more successful in their learning when I started with local topographic maps that included the school and the surrounding area than with places that had mountains or …

Roaming Transition States And Highly Accurate Thermochemistry: A Pepico Study Of Two Small Combustion Systems, Kyle John Covert

University of the Pacific Theses and Dissertations

Two small combustion systems, methyl hydroperoxide (CH₃OOH) and 2-propanol ((CH₃)₂CHOH), were studied using imaging photoelectron photoion coincidence spectroscopy (iPEPICO), which combines photoelectron spectroscopy and photoionization mass spectrometry to detect coincident photoelectron-photoion pairs. In the photon energy range of 11.4–14.0 eV, energy selected CH₃OOH⁺ ions dissociate into CH₂OOH⁺, HCO⁺, CH₃⁺, and H₃O⁺ ions. The lowest-energy dissociation channel is the formation of the cation of the smallest “QOOH” radical, CH₂OOH⁺. A statistical rate model fitted to the …

A Computational Approach To Predicting And Understanding New Psychoactive Substances (Nps) For Developing A Database For State And Federal Crime Laboratories, Caroline Amelia Spencer

Electronic Theses and Dissertations

The object of this dissertation was to use a computational approach to predict and understand new psychoactive substances (NPS) to develop a database for state and federal crime. The primary scope of the dissertation was to better understand the interactions that take place between new psychoactive substances and their corresponding receptors. Through analysis of the interactions between the amino acids within the receptors and the NPS an understanding into the pharmacology and toxicology of these drugs can be gained. NPS such as synthetic cannabinoids fentanyl and its analogs and kratom have become more problematic for both state and federal crime …

Experimental Studies Of Barite Growth Using Hydrothermal Atomic Force Microscopy In Alkali Metal Salt Solutions At 108 C, Sohan Ahmed

Browse all Theses and Dissertations

Barite (BaSO4) growth on the (001) surface was studied under solutions of alkali metal chloride salts (LiCl, NaCl, KCl, RbCl and CsCl) as a function of saturation index and ionic strength of the salts at 108 C. When LiCl was used as the background electrolyte, growth hillocks on the barite surface consisted of both [010] steps and <120> steps at ionic strengths of 0.05 and 0.1 M, but [010] steps were not observed at lower ionic strength. In NaCl solutions, hillocks displayed greater prominence of the [010] steps when compared with LiCl. From the saturation state dependent studies, it was found …

Approaches To The Search Of Platinum Anticancer Agents: Derivatizing Current Drugs And Incorporating Hdac Inhibition, Chao Feng

University of the Pacific Theses and Dissertations

Platinum-based anticancer drugs, such as cisplatin, carboplatin, and oxaliplatin, have been approved for clinical use worldwide for decades. Despite their enormous success, their widespread application is hindered by either cross-resistance or toxic side effects, including nephrotoxicity and neurotoxicity. The need to overcome these drawbacks has stimulated the search for new platinum-based drugs.

This dissertation will start with the accidental discovery of cisplatin, followed by an introduction of other platinum-based anticancer agents, including the action mechanism, general structures, and development history. Picoplatin is a newer generation of platinum-based anticancer agent. The bulky 2-methylpyridine as a non-leaving group on picoplatin could reduce …

Functionalized Peek Analogues From 2,4- And 3,5- Difluorobenzophenone Derivatives, Hannah Fetters

Browse all Theses and Dissertations

The synthesis of N-heterocycle functionalized benzophenone-type monomers and their incorporation into poly(arylene ether ketone)s were explored. Two benzophenone derivatives, 2,4-difluorobenzophenone and 3,5-difluorobenzophenone, were successfully functionalized with a carbazole group, via a copper-catalyzed C-N coupling reaction. Structural characterization was provided by NMR spectroscopy, GC/MS, and elemental analysis. The monomers were covalently incorporated, at various molar ratios, into poly(arylene ether) systems by copolymerization with 4,4’-difluorodiphenylsulfone (DPS) and 4,4’-dihydroxydiphenyl ether (DPE), as well as 4,4’-difluorotriphenylphosphine oxide (dFTPPO) and DPE, via nucleophilic aromatic substitution (NAS) chemistry. Most polymeric materials synthesized provided sufficient molecular weights to cast durable films, and also possessed good thermal stability …

Exploring The Molecular Origin Of Jet Fuel Thermal Oxidative Deposition Through Statistical Analysis Of Mass Spectral Data And Pyrolysis Gas Chromatography/Mass Spectrometry Of Deposits, Krege Matthew Christison

University of the Pacific Theses and Dissertations

ASTM D3241 (Standard Test Method for Thermal Oxidation Stability of Aviation Turbine Fuels) measures the thermal oxidative stability of jet fuels under elevated temperature and pressure conditions. When jet fuels fail ASTM D3241, either at the refinery or in the distribution system, there can be supply disruptions and financial losses. Understanding the causes of poor thermal oxidative stability in jet fuels could help prevent or mitigate issues. In order to develop a deeper understanding of the molecular precursors that lead to ASTM D3241 failures, a number of analytical methodologies and data treatment techniques have been developed, applied, and reported here. …

Computational Studies Of Fullerene-Porphyrin Dyads, Sumreen Gul

Theses and Dissertations

Fullerene (C60) has generated much scientific interest since its discovery due to its novel optical, electronic, and physical properties. Fullerene has been shown to be an excellent electron acceptor and as a result is the acceptor of choice in organic photovoltaics. Porphyrins are excellent electron-donors due to their stability, low ionization potential, and excellent light absorption properties. As a result, fullerene-porphyrin dyads form unique donor-acceptor systems that can be useful for a variety of photoactive applications. In this research, computational studies have been performed on different varieties of C60-Porphyrin dyads and the relationship between molecular topology and the properties of …

Groundwater Hydrogeolgy And Hydrochemistry Of Karst Springs In The Eastern Peninsula Of Fort Hood Military Installation, William Scribner Welles

Electronic Theses and Dissertations

The eastern peninsula of Fort Hood Military Installation is underlain by a complex karst spring network. These springs are a primary water source in a protected habitat for endangered songbirds, which has only recently begun to be fully investigated. These Fredericksburg Group springs express both epigenetic and hypogenetic karst signatures. The study area is part of a paleo reef trend, a hydraulically disconnected segment of the northern section of the Edwards Aquifer. This study utilized standard ion index values, repeated measures, and principal component analyses on the chemical profiles of six perennial springs to classify spring water sources and their …

Molecular Fossils From Phytoplankton Reveal Secular Pco2 Trend Over The Phanerozoic, Caitlyn R. Witkowski, Johan W. H. Weijers, Brian S. Blais, Stefan Schouten, Jaap S. Sinninghe Damsté

Science and Technology Department Faculty Journal Articles

Past changes in the atmospheric concentration of carbon dioxide (PCO2) have had a major impact on earth system dynamics; yet, reconstructing secular trends of past PCO2 remains a prevalent challenge in paleoclimate studies. The current long-term PCO2reconstructions rely largely on the compilation of many different proxies, often with discrepancies among proxies, particularly for periods older than 100 million years (Ma). Here, we reconstructed Phanerozoic PCO2 from a single proxy: the stable carbon isotopic fractionation associated with photosynthesis (Ɛp) that increases as PCO2 increases. This concept has been widely applied to alkenones, but here, we …

Decreasing Phosphatidylcholine On The Surface Of The Lipid Droplet Correlates With Altered Protein Binding And Steatosis, Laura Listenberger, Elizabeth Townsend, Cassandra Rickertsen, Anastasia Hains, Elizabeth Brown, Emily G. Inwards, Angela K. Stoeckman

Chemistry Faculty Publications

Alcoholic fatty liver disease (AFLD) is characterized by an abnormal accumulation of lipid droplets (LDs) in the liver. Here, we explore the composition of hepatic LDs in a rat model of AFLD. Five to seven weeks of alcohol consumption led to significant increases in hepatic triglyceride mass, along with increases in LD number and size. Additionally, hepatic LDs from rats with early alcoholic liver injury show a decreased ratio of surface phosphatidylcholine (PC) to phosphatidylethanolamine (PE). This occurred in parallel with an increase in the LD association of perilipin 2, a prominent LD protein. To determine if changes to the …

Bio-Inspired Polydopamine Surface Modification Of Nanodiamonds And Its Reduction Of Silver Nanoparticles, Yun Zeng, Wenyan Liu, Risheng Wang

Chemistry Faculty Research & Creative Works

Surface functionalization of nanodiamonds (NDs) is still challenging due to the diversity of functional groups on the ND surfaces. Here, we demonstrate a simple protocol for the multifunctional surface modification of NDs by using mussel-inspired polydopamine (PDA) coating. In addition, the functional layer of PDA on NDs could serve as a reducing agent to synthesize and stabilize metal nanoparticles. Dopamine (DA) can self-polymerize and spontaneously form PDA layers on ND surfaces if the NDs and dopamine are simply mixed together. The thickness of a PDA layer is controlled by varying the concentration of DA. A typical result shows that a …

Novel Antibacterial Compounds And Methods Of Making And Using Same, Amit Basu, Christopher W. Reid, Mary Margaret O'Connor, Ethan Lindsay Magno, Mitchell Evan Jamieson, Ryan Daniel Miller

Science and Technology Department Faculty Journal Articles

No abstract provided.

College Of Science And Mathematics Newsletter, Fall 2018, College Of Science And Mathematics, Wright State University

College of Science and Mathematics Newsletters

This 3 page newsletter discusses various happenings within the College of Science and Mathematics. It begins with a letter from the dean, and continues on with news, events, alumni news, and other community news.

Air Pollution [Liberal Arts: Math And Science/Natural Science], Ian Alberts

Open Educational Resources

This assignment was designed for students in the pathways introductory chemistry class and the first year seminar and aligns with the Inquiry and Problem Solving core competency. In this context, there is a focus on “framing the issues” (identifies and/or addresses questions and problems), “evidence gathering” (assembles, reviews and synthesizes evidence from several diverse sources), “evidence” (analyze the data to address the questions posed) and “conclusions” (critical thinking, reflect on the outcomes, draw conclusions and generate new knowledge). There is also a Global Learning component based on comparing data collected locally with corresponding data from other locations or countries. The …

Chem 126a-101: General Chemistry Lab Ii, Chunyan Liu

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 243-101: Organic Chemistry I, Ara Kahyaoglu

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Eps 202-005: Society, Technology And Environment, Michael Bonchonsky

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 125 - General Chemistry I, Alisa Krishtal

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 605-001: Advanced Organic Chemistry Structure And Mechanism, Tamara Gund

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 244a-101: Organic Chemistry Ii Lab, Ngozi Onyia

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 475-101: Biochemistry Lab I, Yong Kim

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 244 - Organic Chemistry Ii, Tamara Gund

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 125-H01: General Chemistry I (Honors), Bhavani Balasubramanian

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 748-101: Nanomaterials, Zafar Iqbal

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 244-003: Organic Chemistry Ii, Ngozi Onyia

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 245-001: Organic Chemistry For Chemical Engineers, Ngozi Onyia

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 243-101: Organic Chemistry I, A Castro

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 222-100: Analytical Chemistry, Hao Chen

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Em 631-851: Legal Aspects Of Environmental Engineering, Michael Bonchonsky

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.