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Articles 6031 - 6060 of 9480

Full-Text Articles in Psychiatry and Psychology

Consumer Trust Ratings After An Airline Accident: An Affective Perspective, Scott R. Winter, Stephen Rice, Ismael Cremer, Rian Mehta Jan 2015

Consumer Trust Ratings After An Airline Accident: An Affective Perspective, Scott R. Winter, Stephen Rice, Ismael Cremer, Rian Mehta

International Symposium on Aviation Psychology - 2015

Fortunately airline accidents are rare; however when one occurs it usually results in widespread media attention. The purpose of this study was to examine how consumers’ trust ratings were impacted when one airline suffered an accident. The findings indicate that System Wide Trust (SWT) theory applies resulting in a trust reduction for all airlines, not just the accident airline. Affect was shown to act as a mediator in only three of the cases, which suggest that consumer’s responses may not be strongly influenced by emotions. Practical implications and limitations of this study are provided.


Concept Of Flight Instructor Assistance In Helicopter Emergency Medical Service Using Pilot Trainee’S Workload Determination, Felix Maiwald, Axel Schulte Jan 2015

Concept Of Flight Instructor Assistance In Helicopter Emergency Medical Service Using Pilot Trainee’S Workload Determination, Felix Maiwald, Axel Schulte

International Symposium on Aviation Psychology - 2015

This article focuses on the development of a tool chain to support the training of helicopter rescue pilots. The aim is to support the training instructor for comprehensible, objective and reliable assessment of the mental state of pilot trainees. Hence this article investigates a method for on-line estimating the mental workload of the pilot and his free/needed cognitive and sensorimotor resources during flight. We further provide a description of the methodological approach and details on the implemented prototype of a flight instructor station as part of our research simulator. In a first simulator study with four subjects the system has …


Anticipatorily Controlled Top-Down Processes Influence The Impact Of Coriolis Effects, Christine M. Talker, K. Wolfgang Kallus Jan 2015

Anticipatorily Controlled Top-Down Processes Influence The Impact Of Coriolis Effects, Christine M. Talker, K. Wolfgang Kallus

International Symposium on Aviation Psychology - 2015

The impact of the vestibular-induced Coriolis illusion becomes apparent in spatial disorientation and symptoms of motion sickness. Empirical data indicated that anticipatory processes, evolved by experience, influence the sensation of Coriolis illusion. We measured subjective well-being and stress responses of 13 experienced pilots and 13 non-pilots in order to study the influence of anticipatorily controlled top-down attention on the impact of Coriolis effects and to examine the role of experience. Subjective data and psychophysiological data (EDA, ECG) were recorded, reflecting the underlying psychological processes involved. Participants distracted by doing a reaction test (experimental group) gave higher drowsiness ratings and higher …


Visual Search And Target Selection Using A Bounded Optimal Model Of State Estimation & Control, Brandon S. Perelman, Christopher W. Myers Jan 2015

Visual Search And Target Selection Using A Bounded Optimal Model Of State Estimation & Control, Brandon S. Perelman, Christopher W. Myers

International Symposium on Aviation Psychology - 2015

Visual attention and motor control are tightly coupled in domains requiring a human operator to interact with a visual interface. Here, we integrate a boundedly optimal visual attention model with two separate motor control models and compare the predictions made by these models against perceptual and motor data collected from human subjects engaged in a parafoveal detection task. The results indicate that humans use an optimal motor control policy limited by precision constraints – humans executed ballistic movements using near-optimal velocity (i.e., bang-bang control), but imprecision in those movements often caused participants to overshoot their targets, necessitating corrective action. Motor …


An Ecological Approach To The Supervisory Control Of Uav Swarms, Christian Fuchs, Clark Borst, Guido De Croon, Rene Van Paassen, Max Mulder Jan 2015

An Ecological Approach To The Supervisory Control Of Uav Swarms, Christian Fuchs, Clark Borst, Guido De Croon, Rene Van Paassen, Max Mulder

International Symposium on Aviation Psychology - 2015

Advances in miniaturized computer technology have made it possible for a single Unmanned Aerial Vehicle (UAV) to complete its mission autonomously. This also sparked interest in having swarms of UAVs that are cooperating as a team on a single mission. The level of automation involved in the control of UAVswarms will also change the role of the human operator. That is, instead of manually controlling the movements of the individual UAVs, the system operator will need to perform higher-level mission management tasks. However, most ground control stations are still tailored to the control of single UAVs by portraying raw flight …


Developing Quantitative Air Traffic Risk-Benefit Pathways For Class Delta Airports: Improving Small Tower Operations, Katherine A. Berry, Michael W. Sawyer, Jordan Hinson Jan 2015

Developing Quantitative Air Traffic Risk-Benefit Pathways For Class Delta Airports: Improving Small Tower Operations, Katherine A. Berry, Michael W. Sawyer, Jordan Hinson

International Symposium on Aviation Psychology - 2015

The primary responsibility of an Airport Traffic Control Tower (ATCT) controller is to prevent collisions between aircraft and other hazards on the surface and in the immediate vicinity. The safety service provided by controllers at towers with larger operations greatly exceeds the costs of establishing those towers. As the number of operations decreases, the costs of operating the tower may begin to outweigh the benefits of staffing the tower. Safety event reports describing instances where an ATCT controller provided a service that reduced the consequences of the event were collected. The reports were classified to identify latent factors, causal factors, …


Impact Of Nextgen On National Airspace Actors, Kelley J. Krokos, Michael W. Sawyer, Katherine A. Berry Jan 2015

Impact Of Nextgen On National Airspace Actors, Kelley J. Krokos, Michael W. Sawyer, Katherine A. Berry

International Symposium on Aviation Psychology - 2015

The Federal Aviation Administration (FAA) is executing a transformation of the National Airspace System (NAS) through the implementation of the Next Generation Air Transportation System (NextGen). This paper presents two research efforts related to understanding and analyzing the effects of planned NextGen changes across NAS actors. American Institutes for Research is completing a Strategic Job Analysis and Strategic Training Needs Analysis of two NAS actors. The results are intended to provide recommendations to selection and training requirements necessary to support NextGen implementation. Fort Hill Group is building Human-System Interaction Models (HSIMs) that identify the human-system interactions affected by planned changes …


Promoting Aviation Safety In Africa: Analysis Of Air Accidents In The Region Between 2004 And 2013, Jacob Joshua Shila, Amadou Anne Jan 2015

Promoting Aviation Safety In Africa: Analysis Of Air Accidents In The Region Between 2004 And 2013, Jacob Joshua Shila, Amadou Anne

International Symposium on Aviation Psychology - 2015

The international air traffic in the Africa region is projected to grow at an average annual rate of 5.1% between 2012 and 2032. The air transport industry in the region has supported about 6.9 million jobs, contributed about $ 67.8 million in economic activity, and about $ 80.5 million in GDP. However, the African continent was ranked last in the Universal Safety Oversight Audit Program (USOAP) report for the year 2012. Efforts by the International Civil Aviation Organization (ICAO), airlines, and governments, and other institutions are currently underway to promote aviation safety. Aviation safety implementation in the Africa region is …


Tactile Cueing Strategies To Convey Aircraft Motion Or Warn Of Collision, Ben D. Lawson, Roger C. Cholewiak, J. Christopher Brill, Angus H. Rupert, Linda-Brooke I. Thompson Jan 2015

Tactile Cueing Strategies To Convey Aircraft Motion Or Warn Of Collision, Ben D. Lawson, Roger C. Cholewiak, J. Christopher Brill, Angus H. Rupert, Linda-Brooke I. Thompson

International Symposium on Aviation Psychology - 2015

This report highlights five current vibrotactile display technologies for conveying aircraft motion or approach to obstacles or waypoints, including: 1) a simple on/off vibration cue that activates when a designated position is reached; 2) vibrations whose on-off pulse rate increases as the vehicle moves faster; 3) vibrations whose fundamental frequency rises to cue the approach of an object; 4) vibrations whose body site of spatial cueing signals self-motion in a manner analogous to tactile cues during sliding along the ground; 5) vibrations whose body site of cueing expands in a manner analogous to visual looming cues. The advantages and limitations …


Audiotactile Aids For Improving Pilot Situation Awareness, J. Christopher Brill, Ben D. Lawson, Angus H. Rupert Jan 2015

Audiotactile Aids For Improving Pilot Situation Awareness, J. Christopher Brill, Ben D. Lawson, Angus H. Rupert

International Symposium on Aviation Psychology - 2015

Up to one-third of all aircraft mishaps are attributable to spatial disorientation (SD), costing lives and millions of dollars. One potential solution is to provide supplementary sensory cues to help improve pilots’ situation awareness (SA). Given existing demands on the pilot’s visual system, audition and touch present the greatest potential for success. However, accurate 3D audio perception may be problematic in noisy operational environments. To determine the effects, participants performed an azimuth cue localization task while listening to 90 dB helicopter noise. Cue modalities conditions included 3D audio, vibrotactile, and audiotactile. Accuracy was better and response times were significantly faster …


Impact Of Caregiving Role In The Quality Of Life Of Family Caregivers For Persons With Alzheimer's Disease, Supriya Sarkar Jan 2015

Impact Of Caregiving Role In The Quality Of Life Of Family Caregivers For Persons With Alzheimer's Disease, Supriya Sarkar

All Graduate Theses, Dissertations, and Other Capstone Projects

This study investigated quality of life of family caregivers of persons with Alzheimer's disease (AD). Caregiving is a strenuous and challenging job. Family caregivers experience poor quality of life after they take the role of caregiving which might be related to depression. Purpose of this study was to find if caregiving duration and depression has any role in affecting family caregivers' emotional, physical, and general health.

Data for this study were collected through electronic and mailed survey methods. The questionnaires completed by subjects: Medical Outcomes Study Short Form 36 (MOS-36) and Center for Epidemiologic Studies Depression Scale (CES-D). Descriptive statistics …


Beginning With Yes: A Review Essay On Michael Wheeler's The Art Of Negotiation: How To Improvise Agreement In A Chaotic World, Leonard L. Riskin Jan 2015

Beginning With Yes: A Review Essay On Michael Wheeler's The Art Of Negotiation: How To Improvise Agreement In A Chaotic World, Leonard L. Riskin

Cardozo Journal of Conflict Resolution

This Review Essay describes the book, introduces a new system for understanding models of negotiation, and uses it to explain and expand upon some of the ideas in The Art of Negotiation. Then it suggests a different title for Wheeler's book, and describes recent efforts to connect improv with negotiation and mediation training and practice. I mean to honor Wheeler's important work by extending it.


The Validity Of The Obsessive-Compulsive Syndromes As Emotional Disorders, Doty Jennings Jan 2015

The Validity Of The Obsessive-Compulsive Syndromes As Emotional Disorders, Doty Jennings

Masters Theses

Recent changes to the Diagnostic and Statistical Manual of Mental Disorders have grouped together syndromes which are referred to as the obsessive-compulsive spectrum (OCS). The grouping of these syndromes is disputed because of lack of empirical verification for an organization purportedly based on research that supports similarity of observed symptoms. The taxonomy of emotional disorders was tested as an alternative model. Consistent with the model of the emotional disorders, this empirical research tested two proposed characteristics. The first was whether three OCS syndromes (hoarding syndrome, body dysmorphic syndrome, and obsessive compulsive syndromes) shared the broad factor of neuroticism or negative …


Keeping Up With The Grandkids: Using Tagteach To Train Baton Twirling Skills In Older Adults, Sarah Elizabeth Hester Jan 2015

Keeping Up With The Grandkids: Using Tagteach To Train Baton Twirling Skills In Older Adults, Sarah Elizabeth Hester

USF Tampa Graduate Theses and Dissertations

Exercise has many physical, cognitive, and social benefits, but the majority of older adults do not meet the recommended level of physical activity (Centers for Disease Control and Prevention, 2014). TAGteach, which combines elements of both behavioral coaching and acoustical feedback, has been demonstrated as an effective way to teach athletic skills (Fogel, Weil, & Burris, 2010; Quinn, Miltenberger, & Fogel, 2015; Stokes, Luiselli, Reed, & Fleming 2010). However, none of the current research on teaching athletic skills targeted an older population. This study evaluated TAGteach in a multiple baseline across behaviors design as a method of teaching 4 basic …


Relaxation Techniques For People With Chronic Obstructive Pulmonary Disease: A Systematic Review And A Meta-Analysis, Eleonora Volpato, Paolo Banfi, Sheena M. Rogers, Francesco Pagnini Jan 2015

Relaxation Techniques For People With Chronic Obstructive Pulmonary Disease: A Systematic Review And A Meta-Analysis, Eleonora Volpato, Paolo Banfi, Sheena M. Rogers, Francesco Pagnini

Dartmouth Scholarship

Chronic Obstructive Pulmonary Disease (COPD) people suffer from severe physical impairments, which often elicit significant psychological distress and impact their quality of life. This meta-analysis aimed to assess evidence from the scientific literature on the effects of relaxation techniques. Methods. We investigated 9 databases to select 25 RCTs. Studies included both inpatients and outpatients with COPD. Both respiratory and psychological outcomes were considered.


Using Auditory Feedback To Improve Dance Movements Of Children With Disabilities, Takema J. James Jan 2015

Using Auditory Feedback To Improve Dance Movements Of Children With Disabilities, Takema J. James

USF Tampa Graduate Theses and Dissertations

Research incorporating behavior analysis to improve sports performance has shown that various feedback types (e.g., video feedback, public posting) can increase skills. Recently, auditory feedback has been shown to be effective. The purpose of this study was to evaluate the utility of auditory feedback to improve dance movements of children with disabilities using an ABAB design embedded in a multiple baseline across participants design. The target behaviors were fundamental dance skills, individualized to each student, and scored using a task analysis to calculate the percentage of correct steps. The results showed that auditory feedback was valuable in increasing the specific …


Using Video Feedback To Increase Job Interview Skills For Young Adults With Developmental Disabilities, Jessica Lynn Moore Jan 2015

Using Video Feedback To Increase Job Interview Skills For Young Adults With Developmental Disabilities, Jessica Lynn Moore

USF Tampa Graduate Theses and Dissertations

Individuals diagnosed with developmental disabilities often lack the skills needed to gain meaningful employment in the community. One crucial skill is interviewing as this is the first and often the only pre-job interaction an individual has with his or her employer. In a short interaction, the person must convey information about specific work history, employability, and a general impression of character. This study evaluated the effectiveness of video feedback in improving job interview behaviors for three young adults with developmental disabilities. The interview related-behaviors were appropriate greeting, responses to interview questions, and appropriate closing statement. The performance across the participants …


Motives For Acquiring And Saving In Hoarding Disorder, Ocd, And Community Controls, Randy O. Frost, Gail Steketee, David F. Tolin, Nicole Sinopoli, Dylan Ruby Jan 2015

Motives For Acquiring And Saving In Hoarding Disorder, Ocd, And Community Controls, Randy O. Frost, Gail Steketee, David F. Tolin, Nicole Sinopoli, Dylan Ruby

Psychology: Faculty Publications

Hoarding disorder (HD) was classified as a separate disorder in DSM-5 (. APA, 2013). However, only recently research on hoarding has begun in earnest, and as of yet, very little research exists on the motivation to acquire and save the excessive volume of possessions seen in patients with this disorder. This investigation examined the frequency of four motives for acquiring and saving possessions that are often reported anecdotally by people with HD (information, emotional reasons, avoid waste, and aesthetic reasons). Comparisons in a sample of 443 participants indicated that those with HD reported higher frequencies of each of these four …


Predictors Of Relationship Dissolution In Lesbian, Gay, And Heterosexual Adoptive Parents, Abbie E. Goldberg, Randi L. Garcia Jan 2015

Predictors Of Relationship Dissolution In Lesbian, Gay, And Heterosexual Adoptive Parents, Abbie E. Goldberg, Randi L. Garcia

Psychology: Faculty Publications

Little work has examined relationship dissolution or divorce in adoptive parents or same-sex parent couples. The current study examined predictors of relationship dissolution across the first 5 years of parenthood among a sample of heterosexual, lesbian, and gay male adoptive couples. Of the 190 couples in the study, 15 (7.9%) dissolved their relationships during the first 5 years of adoptive parenthood. Specifically, 7 of 57 lesbian couples (12.3%), 1 of 49 gay male couples (2.0%), and 7 of 84 heterosexual couples (8.3%) dissolved their unions. Results of our logistic regression analysis revealed that the odds of relationship dissolution were significantly …


Mediators Of Behavior Change Resulting From A Sexual Risk Reduction Intervention For Sti Patients, Cape Town, South Africa, Eileen V. Pitpitan, Seth C. Kalichman, Randi L. Garcia, Demetria Cain, Lisa A. Eaton, Leickness C. Simbayi Jan 2015

Mediators Of Behavior Change Resulting From A Sexual Risk Reduction Intervention For Sti Patients, Cape Town, South Africa, Eileen V. Pitpitan, Seth C. Kalichman, Randi L. Garcia, Demetria Cain, Lisa A. Eaton, Leickness C. Simbayi

Psychology: Faculty Publications

Theory-based sexual risk reduction interventions are often demonstrated effective, but few studies have examined the mechanisms that mediate their behavior changes. In addition, critical contextual factors, such as alcohol use, are often not accounted for by social cognitive theories and may add to the explanatory value of intervention effects. The purpose of this study is to examine the underlying mechanisms driving condom use following a brief sexual risk reduction intervention grounded in the information, motivation, behavioral skills (IMB) model of behavior change. We examined IMB theoretical constructs and alcohol-related contextual factors as potential mediators in separate models. Patients (n = …


Who's On Top? The Mental Health Of Men Who Have Sex With Men, Eric R.A. Carter Jan 2015

Who's On Top? The Mental Health Of Men Who Have Sex With Men, Eric R.A. Carter

Inquiry: The University of Arkansas Undergraduate Research Journal

Despite most men who have sex with men (MSM) expressing intercourse position preference (e.g., “top”, “versatile”, or “bottom”), there is little information regarding sexual behavior and mental health sequelae. From the perspective of gender schema theory, the current study examined how position preference related to gender roles, internalized homophobia, and mental health. A total of 70 MSM (U.S. residents, M age = 28.89 years, 68.6% White) were recruited for an online study and grouped according to position preference. Groups were mostly similar across demographic variables, although bottoms had fewer sexual partners and lower condom use than tops and versatiles. In …


Burnout-Depression Overlap: A Review, Renzo Bianchi, Irvin Sam Schonfeld, Eric Laurent Jan 2015

Burnout-Depression Overlap: A Review, Renzo Bianchi, Irvin Sam Schonfeld, Eric Laurent

Publications and Research

Whether burnout is a form of depression or a distinct phenomenon is an object of controversy. The aim of the present article was to provide an up-to-date review of the literature dedicated to the question of burnout–depression overlap. A systematic literature search was carried out in PubMed, PsycINFO, and IngentaConnect. A total of 92 studies were identified as informing the issue of burnout–depression overlap. The current state of the art suggests that the distinction between burnout and depression is conceptually fragile. It is notably unclear how the state of burnout (i.e., the end stage …


Predicting Antidepressant Treatment Without Controlling For Depression Is Ill-Advised, Renzo Bianchi, Irvin Sam Schonfeld, Eric Laurent Jan 2015

Predicting Antidepressant Treatment Without Controlling For Depression Is Ill-Advised, Renzo Bianchi, Irvin Sam Schonfeld, Eric Laurent

Publications and Research

All in all, the link observed by Madsen et al. (2015) between burnout and antidepressant intake may well conceal an expected relationship between depression and antidepressant intake. The impossibility of ruling out this reasonable alternative hypothesis renders the study inconclusive. We recommend that future research on (psychotherapeutic or pharmacologic) treatments for burnout incorporate measures of depression in order to facilitate research advance on burnout's characterization and burnout-depression overlap.


The Interdependence Of Long And Short-Term Components In Unmasked Repetition Priming: An Indication Of Shared Resources, Matt R. Merema, Craig P. Speelman Jan 2015

The Interdependence Of Long And Short-Term Components In Unmasked Repetition Priming: An Indication Of Shared Resources, Matt R. Merema, Craig P. Speelman

Research outputs 2014 to 2021

It has been suggested that unmasked repetition priming is composed of distinct long-and short-term priming components. The current study sought to clarify the relationship between these components by examining the relationship between them. A total of 60 people (45 females, 15 males) participated in a computer-based lexical decision task designed to measure levels of short-term priming across different levels of long-term priming. The results revealed an interdependent relationship between the two components, whereby an increase in long-term priming prompted a decrease in short-term priming. Both long-term and short-term priming were accurately captured by a single power function over seven minutes …


The Relationship Between School Climate And Mental And Emotional Wellbeing Over The Transition From Primary To Secondary School, Leanne Lester Ms, Donna S. Cross Prof Jan 2015

The Relationship Between School Climate And Mental And Emotional Wellbeing Over The Transition From Primary To Secondary School, Leanne Lester Ms, Donna S. Cross Prof

Research outputs 2014 to 2021

Background: School climate has often been described as the “quality and character of school life”, including both social and physical aspects of the school, that can positively promote behaviour, school achievement, and the social and emotional development of students. Methods: The current study examined the relationship between students’ mental and emotional wellbeing and factors pertaining to school climate, focussing on the domains of safety, social relationships and school connectedness, during the last year of their primary schooling (age 11–12 years) and their first 2 years of secondary school. Data was collected using a self-completion questionnaire, four times over 3 years …


Youth With Type 1 Diabetes Mellitus: An Examination Of Adolescents’ Illness Perceptions And Associated Impact On Health-Related Quality Of Life, Zainab Shahpurwala Jan 2015

Youth With Type 1 Diabetes Mellitus: An Examination Of Adolescents’ Illness Perceptions And Associated Impact On Health-Related Quality Of Life, Zainab Shahpurwala

Electronic Theses and Dissertations

Objectives: To examine the impact of various psychosocial factors (perceived stress, diabetes-specific parental involvement, self-efficacy for diabetes management, and perceived peer support) on adolescents’ self-reported health-related quality of life (HRQoL) and assess the association between these factors and their self-reported HRQoL. To determine if differences in perceptions exist between diabetes camp and non-camp adolescent attendees on the various aforementioned psychosocial factors and their impact on their HRQoL. Methods: The study employed a cross-sectional, non-experimental, quantitative design to address the aforementioned objectives. Adolescents were recruited from multiple sites including diabetes summer camps and university-based and community-based private clinics. Self-administered paper-based surveys …


Sexual Orientation And Non-Suicidal Self-Injury: A Meta-Analytic Review, Kristen L. Batejan, Stephanie Jarvi Steele, Lance P. Swenson Jan 2015

Sexual Orientation And Non-Suicidal Self-Injury: A Meta-Analytic Review, Kristen L. Batejan, Stephanie Jarvi Steele, Lance P. Swenson

Psychology: Faculty Publications

The aim of this study was to conduct the first meta-analysis comparing risk for NSSI between sexual minority and heterosexual persons. Eleven published and 4 unpublished studies were reviewed, describing associations between sexual orientation and NSSI in 7,147 sexual minority and 61,701 heterosexual participants. The overall weighted effect size for the relationship between sexual orientation and NSSI using a random-effects model was OR = 3.00 (95% CI = 2.46–3.66), indicating a medium-to-large effect. Sexual minority adolescents and bisexuals were found to be at particularly high-risk. These findings highlight the need to examine mechanisms linking sexual orientation and NSSI in future …


Using The Symmetry Of False Matches To Solve The Correspondence Problem, Cherlyn J. Ng, Bart Farell Jan 2015

Using The Symmetry Of False Matches To Solve The Correspondence Problem, Cherlyn J. Ng, Bart Farell

Biomedical and Chemical Engineering - All Scholarship

Veridical stereoscopic depth depends on matching corresponding image points. This requires solving the stereo correspondence problem: how are true matches distinguished from false ones? Conventional algorithms select true matches on the basis of feature detection [what do you mean by ‘feature detection’ here? Is there some more specific term?] and adherence to natural statistics. They reject false matches as noise. We propose here an alternative that uses the signals present in false matches to delineate the true solution. When visualized in a Keplerian array, binocular matches are symmetrically reflected about an axis that is a potential solution. Properties such as …


Factors Contributing To Attitudes Towards Disciplinary Parenting Styles, Amanda Marshall Jan 2015

Factors Contributing To Attitudes Towards Disciplinary Parenting Styles, Amanda Marshall

Theses and Dissertations

The debate on whether or not corporal punishment is an acceptable method of discipline for children has been continuously researched and has consistently shown that the use of corporal punishment has a multitude of negative consequences on children (Gershoff, 2013). The present study aims to understand the factors which may contribute to the persistence of these supportive attitudes towards corporal punishment and abuse. The results of this study reveal that the age an individual becomes a parent/guardian is negatively correlated with their support for corporal punishment and acceptance of physical abuse. Strong correlations were also found between acceptance of abuse …


Off-Label Use Of Transmucosal Ketamine As A Rapidacting Antidepressant: A Retrospective Chart Review, Linda Nguyen, Patrick J. Marshalek, Cory B. Weaver, Kathy J. Cramer, Scott E. Pollard, Rae Reiko Matsumoto Jan 2015

Off-Label Use Of Transmucosal Ketamine As A Rapidacting Antidepressant: A Retrospective Chart Review, Linda Nguyen, Patrick J. Marshalek, Cory B. Weaver, Kathy J. Cramer, Scott E. Pollard, Rae Reiko Matsumoto

Faculty Publications & Research of the TUC College of Pharmacy

Objective: This study evaluated the effectiveness and safety of subanesthetic doses of ketamine using an off-label, transmucosal administration route in patients with treatment-resistant depression.

Methods: A retrospective chart review was conducted to identify patients who met the inclusion criteria for treatment-resistant major depressive disorder. Seventeen such patients who received subanesthetic doses of ketamine were included. Patient demographics, efficacy (drug refill, clinician notes), side effects, and concurrent medications were assessed.

Results: Benefit from low-dose transmucosal ketamine was noted in 76% of subjects (average age 48 years, 88% female), with a dose duration lasting 7–14 days. No notable side …