Other Pharmacy and Pharmaceutical Sciences Commons^™

Unused Medication Collection: An Emerging Service-Learning Experience For Pharmacy Students, Anne E. Packard, Maryam Noureldin, A. Carmine Colavecchia, Patricia L. Darbishire, Jennifer Colavecchia

Purdue Journal of Service-Learning and International Engagement

While the U.S. makes up around 5% of the world’s population, we consume approximately 75% of the world’s prescription drugs—well over 4 billion prescriptions per year. Approximately one third of those are never used, creating an array of public health challenges. These challenges include land and water pollution; unintentional inappropriate use and unintentional human, pet, and wildlife poisonings; and intentional drug abuse and diversion. Misuse of prescription drugs now exceeds that of all illegal drugs combined. Reducing the number of medications prescribed is of primary importance, as well as collecting unnecessary medications from households and disposing of them through environmentally …

The Role Of The Pharmacy Team In Atrial Fibrillation Detection In Nonclinical Settings, Brian C. Hazelrigg, Monica L. Miller, Sotiris Antoniou, Jagjot Chahal, Sadeer Fhadil

Purdue Journal of Service-Learning and International Engagement

Atrial Fibrillation (AF) is a common cardiac/heart disease that increases a person’s risk of death, making early identification significant in overall disease management. Throughout my time in pharmacy school, I [Brian] have developed an interest in cardiology and research. During my last year of pharmacy school, I spent eight weeks at St. Bartholomew’s Hospital, in London, England, one of the largest cardiac centers within Europe, on an experiential training experience. While there, I had the opportunity to study specifics about many cardiac illnesses, with a focus on atrial fibrillation, and provide education to patients living with this disease. In addition …

Safe Medication Disposal In Underserved Communities, Elaina Etter

Purdue Journal of Service-Learning and International Engagement

Of the 130 Americans who will die each day from opioid overdose, 46 will have overdosed on prescription opioid medications. The opioid epidemic has become one of our nation’s largest public health crises. Because many individuals may have access to prescription medications of family members or friends, responsible medication disposal has become increasingly important to prevent harm.

This fall, I worked on a professional project at local Federally Qualified Health Centers (FQHCs), which aimed to increase education about safe medication disposal. These clinics provide comprehensive healthcare services to underserved patients, many of whom live in rural areas or have limited …

Healthcare Delivery And Pharmacy Workforce: Pharmacy (Wo)Manpower - 2016 And Beyond..., Crystal Zheng, Mariah Steele, Noori Lee, Sabrina Hamman, Stanley Kent

Pharmacy and Wellness Review

No abstract provided.

Population Health Management, Data And Technology, Helena Ladd, Cody Hepp, Anna Mccloud, Hannah Granger, Mary Ellen Hethcox, Samuel Calabrese

Pharmacy and Wellness Review

No abstract provided.

Professional Priorities To Optimize Patient Outcomes, Megan Bishop, Joelle Hall, Mikayla Shea, Katherine Liu, Steven J. Martin, John Armistead

Pharmacy and Wellness Review

No abstract provided.

The Road To Provider Status: Legislative Obstacles And Precursors, Todd A. Tucker Jr., Sarah Turley, Kaila Bollinger, Lara Long, Jenelle Sobotka, Amy Fanous

Pharmacy and Wellness Review

No abstract provided.

Adderall®: Understanding And Preventing Its Abuse Amongst College-Aged Students, Adam Trimble, Cody Hay, Lindsay Mark, Heather Helsel, Tom Kier

Pharmacy and Wellness Review

No abstract provided.

Different Types Of Board Certified Pharmacists, Taylor Alane Beale, Megan Ruffner, Joanne Kien Tran, Lindsay A. Fleegle, Jennifer J. Kline, Pat Parteleno

Pharmacy and Wellness Review

No abstract provided.

How To Set Up An Outreach Event: A Guide For Pharmacists, Kimberly Baucher, Andrew Skouby, Tanya Wilsmann, Eric Stack, Kristen Finley Sobota

Pharmacy and Wellness Review

No abstract provided.

Prescription Drug Abuse: What Are We Doing About It?, Heather Helsel, Thomas Otroba, Juliana Zschoche, Brandon Haas

Pharmacy and Wellness Review

No abstract provided.

Genetic Predispositions To Opioid Addiction, Legislative Action And Implications To Pharmacy Practice, Adam N. Trimble, David N. Jones, Courtney L. Salvino, Michael M. Milks, David Kisor

Pharmacy and Wellness Review

Prescription pain-relievers can be powerfully effective agents in the treatment of moderate to severe pain; however, these drugs are also strongly associated with drug abuse and addiction. In the brain, opioid analgesics bind to various receptors in the mesocorticolimbic dopaminergic pathways, which play a multifaceted interaction of role in reward. Several specific single nucleotide polymorphisms (SNPs) have been identified as potential genetic factors that increase an individual's risk for addiction; however, confounding studies and lack of large trials prohibit definitive conclusions from being drawn. As a result of genetic testing, federal and state laws have been enacted to protect individuals …

The Role Of The Pharmacist In Patient-Centered Medical Homes, Eric Stack, Kevin Stack, Stelios Theophanous, Karen L. Kier

Pharmacy and Wellness Review

No abstract provided.

Assessment Of Pharmacist Attitudes Regarding Introductory Pharmacy Practice Experience Hours, Donald Bond, Lindsay Fleegle, Olivia Hiddleson, Alexis Klefeker, Amanda Lovell, Kyle Rush, Christina Spinaris, Jamie Amero, Maryanne Ventura, Donald L. Sullivan

Pharmacy and Wellness Review

Introductory pharmacy practice experience (IPPE) hours are a means of integrating experiential education as a key role early on in pharmacy education. The Accreditation Council for Pharmacy Education (ACPE) has offered little guidance on mandatory and specific objectives to accomplish during IPPE hours, thus it is possible that preceptors do not feel adequately prepared, nor do they have a full understanding of what is required of them when they agree to precept an IPPE student. Given the lack of previous research conducted, the objective of this study was to obtain an understanding of the general attitude that preceptors have toward …

New Federal Ban On Bath Salts: Attempts To Contain A Growing Epidemic, Courtney L. Salvino, Adam N. Trimble, David N. Jones, Margaret Rowland, Michael M. Milks

Pharmacy and Wellness Review

No abstract provided.

A Pharmacist's Guide To Vaccinations, Amy Gillman, Jessica Beck, Vincent Wu

Pharmacy and Wellness Review

No abstract provided.

Hormonal Therapy And Preventive Care Of Transgender Patients, Angela Chu, Jana Randolph, Austin Hopkins, Victoria Cho, Sophocles Chrissobolis

Pharmacy and Wellness Review

Transgenderism occurs when an individual's gender identity conflicts with the individual's biological sex. A variety of methods may be used in order to reconcile this disparity in transgender individuals including psychological counseling, cross-sex hormone therapy and sex reassignment surgery. The most important role for pharmacists in the treatment of transgender patients is in dispensing hormonal medications for cross-sex treatment. Hormone therapy may be used to suppress characteristics of the patient's biological sex as well as to induce development of characteristics that correlate with the patient's gender identity. In male-to-female (MtF) transgender patients, the most commonly used medications include agents which …

Pharmacologic And Nonpharmacologic Approaches To Palliative Care In Oncology, Daniel Powell, Sunitha Johns, Samia Alam, Isabel E. Cwikla, Brendan Rasor, David W. Koh

Pharmacy and Wellness Review

In recent decades, few fields have changed as drastically as oncology. A wide variety of approaches must be taken in order to best care for cancer patients. With the globalization of health care and modern society, nontraditional management of cancer symptoms is once again increasing in popularity. The National Comprehensive Cancer Network (NCCN) has also recently updated their palliative care guidelines. These guidelines provide a detailed approach for the care of a wide range of cancer patients but largely focus on traditional pharmacotherapy. An increasing number of studies are being conducted on nonpharmacologic approaches to care for patients with cancer. …

Antibiotic Stewardship And Overcoming Antibiotic Resistance In Upper Respiratory Tract Infections, Katherine Elsass, Austin Hilverding, Steve Blake, Brendan Rasor, Steven N. Leonard

Pharmacy and Wellness Review

Antibiotic resistance has rapidly become one of the most significant challenges facing modern health care. Despite widespread public education efforts by the national government and health organizations worldwide, there remains a significant lack of public understanding of antibiotic resistance, how to prevent it and the implications if the science and health care communities fail to find a solution. The Centers for Disease Control and Prevention (CDC) and the American College of Physicians (ACP) recently published updated guidelines for appropriate antibiotic use in upper respiratory tract infections. These guidelines include several key recommendations for acute bronchitis, pharyngitis and acute rhinosinusitis (including …

A Pharmacist's Role In Educating On The Health Risks Of Smoking During Pregnancy And Helping Patients With Smoking Cessation, Alexandra Herman, Cassandra Hacker, Emily Wells, Brian Heilbronner, Brittany L. Long

Pharmacy and Wellness Review

While many people know smoking causes cancer, heart disease and other major health problems, smoking during pregnancy causes additional fetal health complications including birth defects, premature birth and infant death. Cigarettes contain carbon monoxide and nicotine, both of which can cause a decrease in oxygen delivery to the fetus' developing tissues causing organs like the brain, lungs, kidneys and ears not to develop properly. If children are exposed to these toxins through secondhand smoke after birth, they are more likely to experience severe health problems such as ear infections, cataracts, lung cancer and heart disease. It is also known that …

Legionnaires' Disease, A Rising Occurrence In The United States, Jennifer Harklerode, Olivia Henton, Myranda Smith, Rebecca Worden, Andrew Roecker

Pharmacy and Wellness Review

Legionella pneumophila, a microscopic bacterium usually responsible for a number of illnesses and fatalities, can eliminate a local population, a region or even a nation. In 1976, L. pneumophila was first discovered due to a number of cases presenting with pneumonia-like symptoms. These cases occurred in an isolated population attending an American Legion convention in Philadelphia, Pennsylvania, therefore lending to the name Legionella. Usually found in aquatic environments such as lakes, streams, cooling towers, air conditioning systems and hot tubs, its ability to thrive in artificial and natural environments makes it an ideal bacterium. L. pneumophila can be transmitted via …

Evaluating The Role Of Fecal Microbiota Transplant In The Treatment Of Clostridium Difficile Infection, Anh Dao Le, Olivia Henton, Shane Bogusz, Brian Heilbronner, Jessica Hinson

Pharmacy and Wellness Review

Fecal microbiota transplant (FMT) therapy is an increasingly prevalent treatment option for Clostridium difficile infection (CDI). Clostridium difficile infection is an aggressive and potentially fatal disease state, and antibiotic therapy often fails to resolve the disease state effectively. Clostridium difficile infection occurs most commonly subsequent to the use of antimicrobial agents that disrupt the natural bacterial flora of the gastrointestinal (GI) tract. Since disease state pathophysiology operates in this way, researchers have experimented with ways to restore GI flora to a natural state in which nonpathogenic bacteria can proliferate. Probiotic agents do not impose an acute enough response to recreate …

Latest Trends In The Heroin Epidemic And The Responsibility Of The Pharmacist In Controlling Heroin Abuse, Alexandra Herman, Cassandra Hacker, Emily Wells, Sabrina Hamman, Manoranjan D'Souza

Pharmacy and Wellness Review

Over the last few years, there has been an exponential increase in morbidity and mortality associated with heroin abuse. The current rise in heroin abuse and overdose is attributed to widespread use and abuse of prescription opioids, which can produce significant euphoric effects in humans. In fact, reports suggest that heroin abusers initially become addicted to prescription opioids but subsequently switch to heroin because it is cheaper and more easily available than prescription opioids. Over the years, the purity of heroin available for illicit use has been on the decline. Smugglers and heroin vendors have started mixing heroin with other …

Maternal And Infant Health Benefits Related To Infantile Feeding Methods, Michaela Wolford, Alexa Bouts, Carmen Lariccia, Cara Walden, Anh Dao Le, Andrew M. Roecker

Pharmacy and Wellness Review

Human breast milk is known to provide the most complete nutrition to growing infants. There may be more gained from breastfeeding than simply nutritional fulfillment-recent research has uncovered benefits related to the development and health of infants. Breastfeeding has been shown to stimulate immune system development by exposing the infant to bacteria and antibodies from the mother. Breastfeeding may also benefit nursing mothers by improving insulin sensitivity and glucose tolerance as well as decreasing postpartum weight gain. In place of breastfeeding, formulas are able to provide an infant with necessary nutrition. Many infant formulas have been enriched with probiotics and …

Zika Virus Induced Neurological Disorders And Impacts On Public Health, Alexandra Herman, Martha Zimmerman, Olivia Vanscoy, Olivia Henton, Lindsey Peters

Pharmacy and Wellness Review

Zika virus is a public health emergency of international concern. Zika virus (ZIKV) is a mosquito-borne pathogen that is carried by the Aedes genus. Zika is spread through direct bite and nonvector transmission. Most individuals infected with Zika will be asymptomatic, but some may present nonspecific viral symptoms. A rising number of neurological disorders in newborns whose mothers were infected with ZIKV during pregnancy have been reported due to recent outbreaks. Neurological disorders affect both the central and peripheral nervous systems and can result from bacterial, viral, fungal or parasitic infections of the nervous system or from the immune response …

Zika Virus: Infectious Process And Public Health Response, Morgan Homan, Julia Dickman, Jenna Deininger, Austin Hopkins, Olivia Henton, Steven N. Leonard

Pharmacy and Wellness Review

The Zika virus has become a growing concern as a global pandemic. Since being identified in Uganda in 1947, the virus has spread around the world, recently emerging in South America with a great impact on Brazil. As of 2016, Zika has made its appearance in the United States and is now actively being transmitted in Florida. The virus is a mosquito-vectored flavivirus primarily transmitted by the Aedes mosquito which infects a human through biting. Transmission through sexual intercourse is also possible as well as transmission from a pregnant woman to her fetus. This latter form of transmission presents the …

Heterogeneity And Plasticity Of Human Breast Cancer Cells In Response To Molecularly-Targeted Drugs, Emira Bousoik, Ramina Nabiee, Farideh Amirrad, Ashley Nichols, Rebecca Witt, Parvin Mahdipoor, Hamidreza Montazeri Aliabadi

Pharmacy Faculty Articles and Research

Non-responsive subpopulation of tumor cells, and acquired resistance in initially responsive cells are major challenges for cancer therapy with molecularly-targeted drugs. While point mutations are considered the major contributing factor to acquired resistance, in this study we explored the role of heterogeneity and plasticity of selected human breast cancer cell lines (MDA-MB-231, MDA-MB-468, and AU565) in their initial and adjusted response, respectively, to ruxolitinib, everolimus, and erlotinib. After determination of lethal concentration for 50% cell death (LC50), cells were exposed to selected drugs using three different approaches: single exposure to 4 × LC50 and collection of surviving cells, multiple exposures …

The Role Of A Home Health Care Pharmacist-Medication Management For Patients With Feeding Tubes, Lydia Suchecki, Sabrina Hamman, Rachel Muhlenkamp, Eyob D. Adane

Pharmacy and Wellness Review

Home health care is a method of medical care that patients receive inside their home under the supervision of a collaborative team of physicians, nurses, pharmacists and sometimes other health care professionals. Home health provides patients with the same standard of care that they would be receiving in a nursing home or hospital. However, the treatment and continued monitoring at home reduces health care costs and makes the patient feel more comfortable. Pharmacists analyze, resolve and prevent medication-related problems in home health care in order to minimize hospitalizations and improve patient quality of life. Pharmacist involvement with other health care …

Pharmacists' Role In Preconception Care, Kelsey Weisenburger, Jamie Kellner, Hannah Granger, Natalie A. Dipietro Mager

Pharmacy and Wellness Review

Within the current health care system, preconception care is often a misunderstood topic and, in many cases, a missed opportunity to improve women's health and decrease adverse pregnancy outcomes. It is important that preconception care is delivered to all women of childbearing age, regardless of pregnancy intentions, as the interventions associated with preconception care can help improve a woman's health overall. In 2006, the Centers for Disease Control and Prevention (CDC) released four goals, 10 recommendations, and 14 evidence-based interventions regarding preconception care. Pharmacists can have a significant role in ensuring preconception care for all women through the application of …

Treatment Of Attention-Deficit Hyperactivity Disorder In Children And Adolescents: Benefits And Challenges, Kaila Bollinger, Albert Bui, Adam Smith, Kelsey Fink, Manoranjan D'Souza

Pharmacy and Wellness Review

Attention-deficit hyperactivity disorder (ADHD) is a neurobehavioral disorder affecting approximately 11 percent of the country's children and adolescents, between the ages four to seventeen years. Stimulant medications such as methylphenidate and amphetamines are the first-line of treatment for ADHD. The increasing use of these stimulant medications has resulted in increased media attention and raised questions about their efficacy and safety. This review focuses on the history of stimulant use in ADHD, the disease's pathophysiology, the long-term benefits of pharmacotherapy, and the possible subsequent adverse effects associated with prolonged stimulant use in children and adolescents suffering from ADHD. Furthermore, we will …