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Full-Text Articles in Other Dentistry

Dental Care During The Covid-19 Pandemic: Patient Perceptions Of Barriers To Dental Care, Covid-19 Safety Precautions, And Administration Of The Covid-19 Vaccine At The Dental Office, Brunilda Lugo, Sheri Denslow, Jill Fromewick, Scott Davis, Katherine Jowers, J. Amadeo Valdez Feb 2023

Dental Care During The Covid-19 Pandemic: Patient Perceptions Of Barriers To Dental Care, Covid-19 Safety Precautions, And Administration Of The Covid-19 Vaccine At The Dental Office, Brunilda Lugo, Sheri Denslow, Jill Fromewick, Scott Davis, Katherine Jowers, J. Amadeo Valdez

HCA Healthcare Journal of Medicine

Background

The Mountain Area Health Education Center (MAHEC) Dental Health Center sought to learn how COVID-19 affected dental care attainment and patient perceptions of appropriate safety measures, as well as their acceptance of the dental office as a site for COVID-19 vaccinations.

Methods

A cross-sectional online survey of dental patients was performed to inquire about barriers to care, safety precautions, including COVID-19 testing, and the acceptability of vaccination for COVID-19 in the dental office. All adult patients of the MAHEC Dental Health Center with an email address on file and a clinic visit in the past year were randomized for …


Use Of Mouthguards In Sports: Friend Or Foe When It Comes To Oral Health?, Jacob Daniel Gardner, Claudia Freitas Feb 2023

Use Of Mouthguards In Sports: Friend Or Foe When It Comes To Oral Health?, Jacob Daniel Gardner, Claudia Freitas

Annual Research Symposium

No abstract provided.


Effect Of Chlorhexidine On Nanoleakage And Bond Durability Of Two Adhesives To Dentin: An In Vitro Study, Rowayda Anwar Eltarawy, Essam Naguib, Ahmed Z. Elhoshy, Sara H. Younis Jan 2023

Effect Of Chlorhexidine On Nanoleakage And Bond Durability Of Two Adhesives To Dentin: An In Vitro Study, Rowayda Anwar Eltarawy, Essam Naguib, Ahmed Z. Elhoshy, Sara H. Younis

Future Dental Journal

Abstract

Aim: This study aimed to investigate the effect of chlorhexidine (CHX) on nanoleakage (NL) and dentin bond durability of two adhesives after water storage.

Materials and Methods: Thirty-six extracted molars were divided into three groups and their buccal surfaces were reduced to expose flat dentin surfaces. In group 1 Single Bond Universal Adhesive (SBU) was used, in group 2 Peak universal Bond (PUB) was applied while in group 3 Chlorhexidine Gluconate Disinfecting Solution followed by Single Bond Universal Adhesive (CHX+SBU) was used. Application of resin composite restorations was performed in all three groups. For each bonding procedure, …


Assessing Faculty Preference Regarding Online Tools For Assessment In Medical Education: A Cross-Sectional Multi-Center Study, Zarreen Raza, Samira Adnan, Sanaa Ahmed, Zahid Memon, Saad Saleem, Ziyad Sanaullah Jan 2023

Assessing Faculty Preference Regarding Online Tools For Assessment In Medical Education: A Cross-Sectional Multi-Center Study, Zarreen Raza, Samira Adnan, Sanaa Ahmed, Zahid Memon, Saad Saleem, Ziyad Sanaullah

Internet Journal of Allied Health Sciences and Practice

Purpose: E-assessment is a novel practice in developing countries; hence it is essential to determine the online platforms and tools preferred by health sciences education faculty for online assessment. The purpose of this study was to assess the preference of faculty in medical and dental education regarding the online tools for e-assessment of undergraduate students. Methods: This cross-sectional, descriptive study was conducted from June until August 2020 on the faculty of medical and dental undergraduate programs of private and public sector institutes across Karachi, with a sample size of 152. Data was collected through convenience sampling using a validated questionnaire …


Three-Dimensional Evaluation Of The Mandibular Lingula On Cone-Beam Computed Tomographic Images In The Turkish Population, Zerrin Unal Erzurumlu, Damla Torul Dec 2022

Three-Dimensional Evaluation Of The Mandibular Lingula On Cone-Beam Computed Tomographic Images In The Turkish Population, Zerrin Unal Erzurumlu, Damla Torul

Journal of Dentistry Indonesia

Objective: The purpose of this study was to provide morphometric and anatomical data for mandibular lingula (Li) in The Turkish population using three dimensional-cone beam computed tomography (3D-CBCT) images. Methods: CBCT images of the patients taken between July 2020 and March 2021, were retrieved from the archival records. A total of 100 Li’s of 50 patients who met the criteria of this study were evaluated. The distances between the tip of the Li and ramal landmarks/occlusal plane were measured and the shape of the Li was evaluated on 3D-CBCT images. Results: CBCT images of the 50 patients (19 males and …


Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila Dec 2022

Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila

Journal of Dentistry Indonesia

Nevoid Basal Cell Carcinoma Syndrome, also called as Gorlin Gotz syndrome is an autosomal dominant disorder characterized by the presence of multiple odontogenic keratocysts (OKCs) of the jaw, basal cell carcinomas and skeletal anomalies. Presence of multiple OKCs is the first clinical manifestation in majority of the cases. Early diagnosis and treatment are of utmost importance in reducing the severity of this syndrome. We hereby report a rare case of Gorlin Goltz syndrome in a 28 years old female patient who presented with multiple cystic lesions in the jaws. Present case also highlights the clinical, radiographic and histopathologic features of …


Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja Sep 2022

Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja

School of Medicine Faculty Publications

Adherence to the dental practice regulatory guidelines instituted during the COVID- 19 pandemic is essential to minimize the transmission of SARS-CoV-2 strains. Given the lack of a valid and reliable survey tool to assess the adherence to dental practice guidelines, this study aims to develop, validate, and test a survey tool on a pilot sample of dental clinicians practicing in India. A survey tool was developed/validated through a sequential phasic approach: Phase Ideveloping survey using conceptual and literature framework; Phase II: ascertaining its validity and reliability; Phase III: pilot testing; and Phase IV: assessing construct validity by exploratory factor analysis …


Uncut Enamel For Optimizing Bonded Composite Restoration On Multiple Diastema Closure Cases, Citra Kusumasari, Meiken Hayashi, Yasushi Shimada Aug 2022

Uncut Enamel For Optimizing Bonded Composite Restoration On Multiple Diastema Closure Cases, Citra Kusumasari, Meiken Hayashi, Yasushi Shimada

Journal of Dentistry Indonesia

The main advantage of using a minimal invasive strategy concept by uncut enamel technique while doing direct composite restoration is to create a color and translucency close to the natural teeth with long-term bonding durability. Objective: This case report presents an uncut enamel technique for multiple diastema closure cases using direct composite restoration. Case Reports: an 18-year-old male and a 50-year-old female patient complained of diastema in their upper front teeth and requested aesthetic correction. Digital mock-up was made prior to the uncut enamel technique for showing the expected results to the patient and as a guidance for the …


The Practices Of Treating Deep Carious Lesions Compared With The Dental Curriculum In Turkish Dentistry, Leyla Kerimova, Erdem Karabulut, Kivanç Yamanel, Neslihan Arhun Aug 2022

The Practices Of Treating Deep Carious Lesions Compared With The Dental Curriculum In Turkish Dentistry, Leyla Kerimova, Erdem Karabulut, Kivanç Yamanel, Neslihan Arhun

Journal of Dentistry Indonesia

Objective: The aim of this cross-sectional study is to investigate Turkish dentists’ opinions and preferences regarding the management of deep carious lesions and compare them with modern dental education concepts as provided by dental schools. Methods: Questionnaire 1 and Questionnaire 2 were sent separately to dental practitioners via the Turkish Dental Association and to university department heads of restorative dentistry. The data obtained were analyzed using chi-square tests and one-way ANOVA tests (p < 0.05). Results: Regarding Questionnaire 1, most of the dentists (89.3%) responded that caries lesions should be removed completely up to the hard cut-off condition of …


Fractal Analysis Of Subchondral Cyst At Mandibular Condyle Detected On Panoramic Radiograph In A Group Of Thai Population, Aloysius Putut Wijanarko, Preeyaporn Srimawong, Suchaya Pornprasertsuk-Damrongsri, Apirum Janhom Aug 2022

Fractal Analysis Of Subchondral Cyst At Mandibular Condyle Detected On Panoramic Radiograph In A Group Of Thai Population, Aloysius Putut Wijanarko, Preeyaporn Srimawong, Suchaya Pornprasertsuk-Damrongsri, Apirum Janhom

Journal of Dentistry Indonesia

Objectives: This study aimed to analyze subchondral cyst on the mandibular condyle using fractal dimension (FD) measurement on a panoramic radiograph. Methods: This retrospective study examined 15 patients aged 24 to 75 years who had undergone panoramic radiography and cone-beam computed tomography on both sides of the mandibular condyles, between January 2013 and November 2017, in the Oral and Maxillofacial Radiology Clinic, Dental Hospital, Mahidol University. These 15 patients, all of whom had a subchondral cyst on one side of the mandibular condyle, constituted both the study and control groups: the 15 affected sides constituted the study group, …


Primary Oral Myiasis Of Anterior Maxilla In An Intellectually Disabled Female – A Case Report, Sridhar M, Shivayogi Charantimath, Anjana Bagewadi, Lokesh Kumar S, Arun Panwar, Jayapriya T, Vaishali Keluskar Aug 2022

Primary Oral Myiasis Of Anterior Maxilla In An Intellectually Disabled Female – A Case Report, Sridhar M, Shivayogi Charantimath, Anjana Bagewadi, Lokesh Kumar S, Arun Panwar, Jayapriya T, Vaishali Keluskar

Journal of Dentistry Indonesia

“Myiasis” is a term used to represent invasion caused by fly larvae that affect organs and tissues of human beings and feeds on the host tissue. It is a rare and non-specific pathology that varies according to the species of fly larvae and the area of the body involved. Various factors like extraction wounds, uncontrolled diabetes, necrotic tissues, alcohol addiction, poor oral hygiene, immunocompromised conditions and people with special care needs like debilitated or mentally challenged individuals predispose to develop myiasis. We hereby report a case of oral myiasis of the maxillary anterior region of the palate and labial mucosa, …


Comparisons Of Microleakage And Scanning Electron Microscope Sem Analyzes Of The Use Of Different Pulp Coverage Materials, Yasemin Yavuz, Sedef Kotanli, Mehmet Sinan Doğan, Kemal Doğan Aug 2022

Comparisons Of Microleakage And Scanning Electron Microscope Sem Analyzes Of The Use Of Different Pulp Coverage Materials, Yasemin Yavuz, Sedef Kotanli, Mehmet Sinan Doğan, Kemal Doğan

Makara Journal of Health Research

Background: The aim of this study was to compare three different pulp coverage materials with calcium silicate content considering microleakage in the cavity floor and evaluate the gaps with a stereomicroscope and scanning electron microscope SEM.

Methods: A total of 40 human molar teeth were used in this study, and class V (4 mm mesio-distal × 3 mm gingivo-occlusal × 3 mm depth) cavities were prepared. The samples were divided into four groups (N = 10), including NeoPutty(Nusmile), Biodentin (Septodont), and TheraCal PT (Bisco). All groups were restored using Single Bond Universal adhesive and Filtek Z250 (3M ESPE). …


Early Eruption Of All Permanent Teeth, Including The Upper Canines, In A Nine-Year-Old Child Who Was Born Prematurely; Case Report, Bassam Ali Al-Turaihi, Israa Hussein Ali Aug 2022

Early Eruption Of All Permanent Teeth, Including The Upper Canines, In A Nine-Year-Old Child Who Was Born Prematurely; Case Report, Bassam Ali Al-Turaihi, Israa Hussein Ali

Maaen Journal for Medical Sciences

The world health organization (WHO) define the premature birth as a birth occur before 37 weeks of gestation or if the birth weight is below 2500 g. Our case subjected for both criteria of the preterm definition. ((1)) ((2)) The case was born before 31st week with 1300 g birth weight with stormy beginning of life in the first three months in the hospital according to the history taken from general practitioner (GP) for that reason their parents tack care about his general health and specifically oral health and development. Throughout his life he developed healthy with no medical problem. …


An Exploratory Look Into The Effects Of Mississippi's Population Decline On Rural Dental Care, Allen Bailey Saffold May 2022

An Exploratory Look Into The Effects Of Mississippi's Population Decline On Rural Dental Care, Allen Bailey Saffold

Honors Theses

Literature reviews and interviews with dentists working in rural Mississippi counties examined the effects of population decline on rural dental care in Mississippi. With the state’s continual population decline, loss of industry follows a loss of people. Through a cascade of effects, this can further reduce underserved areas’ access to dental care. In order to address the issue of rural Mississippi continuing to be underserved, policies need to be implemented that will make rural practice at least enticing if not desirable.


Dental Students' Perceptions Of Dental Hygienists' Education And Scope Of Practice, Cynthia Metzger May 2022

Dental Students' Perceptions Of Dental Hygienists' Education And Scope Of Practice, Cynthia Metzger

Electronic Theses and Dissertations

Oral health is strongly correlated to systemic health in the United States. Dental professionals play a significant role in addressing the oral health and prevention of disease for populations in the United States. Because many areas in the United States lack access to dental care, the federal government considers dental hygienists part of the solution. It is now paying attention to restrictive dental hygiene scope of practice rules in each state. State dental boards, comprised mainly of dentists, make these rules based on their perception of dental hygienists' lack of education. This study explored fourth-year dental students' perceptions of the …


Crispr-Cas In The Field Of Dentistry: A Comprehensive Collection Of The Potential Uses Of Crispr-Cas9 In Dental Health Care, Lexi Elaine Bales May 2022

Crispr-Cas In The Field Of Dentistry: A Comprehensive Collection Of The Potential Uses Of Crispr-Cas9 In Dental Health Care, Lexi Elaine Bales

Chancellor’s Honors Program Projects

No abstract provided.


Mandibular Bone Changes In Children And Adolescents With Type 1 Diabetes Mellitus In Different Metabolic Control States, Hümeyra Tercanlı Alkış, Burcu Yağmur, Mesut Parlak, Hüseyin Karayılmaz Apr 2022

Mandibular Bone Changes In Children And Adolescents With Type 1 Diabetes Mellitus In Different Metabolic Control States, Hümeyra Tercanlı Alkış, Burcu Yağmur, Mesut Parlak, Hüseyin Karayılmaz

Journal of Dentistry Indonesia

Objective: The aim of this study is to evaluate the cortical and trabecular mandibular bone morphology of children and adolescents with type 1 diabetes mellitus (DM) and control group utilizing fractal dimension analysis (FDA) and different panoramic radiomorphometric indices through digital panoramic radiographic images (DPRIs). Methods: The study included 57 patients for the type 1 DM group (25 male and 32 female with a mean age of 11.5±2.4 years) and 57 patients for the control group (28 male and 29 female with a mean age of 10.5±2.1 years). The type 1 DM group was divided into the well-controlled, moderately-controlled, and …


Dental Students’ Perception, Attitude And Willingness To Interact With Mental Illness Patients: A Multicentre Cross-Sectional Study, Mazarina Nurdini Malek, Zainab Mat Yudin, Nor Faharina Abdul Hamid, Nor Asilah Harun, Suzanna Awang Bono, Mohamad Arif Awang Nawi Apr 2022

Dental Students’ Perception, Attitude And Willingness To Interact With Mental Illness Patients: A Multicentre Cross-Sectional Study, Mazarina Nurdini Malek, Zainab Mat Yudin, Nor Faharina Abdul Hamid, Nor Asilah Harun, Suzanna Awang Bono, Mohamad Arif Awang Nawi

Journal of Dentistry Indonesia

Mental illness is a psychological impairment involving emotions, cognitions, and behaviors, and its prevalence is increasing worldwide. Dental students may encounter patients with underlying psychological problems during their training. Objective: To evaluate dental students’ perception, attitude, and willingness to interact with patients with mental illness. Methods: A multi-center cross-sectional study was conducted involving undergraduates at three dental institutions in Malaysia using an online self-administered questionnaire. Descriptive data analysis was conducted and statistical analysis using chi-square test was done for associations (p < 0.05). Results: The response rate was 63% (225); the majority of respondents were female (77.8%) and of Malay ethnicity (88.4%). …


Deep Margin Elevation: A Literature Review, Theodora Kalliopi Samartzi, Dimokritos Papalexopoulos, Panagiotis Ntovas, Christos Rahiotis, Markus Blatz Mar 2022

Deep Margin Elevation: A Literature Review, Theodora Kalliopi Samartzi, Dimokritos Papalexopoulos, Panagiotis Ntovas, Christos Rahiotis, Markus Blatz

Departmental Papers (Dental)

A conservative approach for restoring deep proximal lesions is to apply an increment of composite resin over the preexisting cervical margin to relocate it coronally, the so-called “deep margin elevation” (DME). A literature search for research articles referring to DME published from January 1998 until November 2021 was conducted using MEDLINE (PubMed), Ovid, Scopus, Cochrane Library and Semantic Scholar databases applying preset inclusion and exclusion criteria. Elevation material and adhesive system employed for luting seem to be significant factors concerning the marginal adaptation of the restoration. This technique does not affect bond strength, fatigue behavior, fracture resistance, failure pattern or …


Color-Blind Racial Attitudes In Practicing Dental Hygienists, Emily A. Ludwig, Susan L. Tolle, Jessica R. Suedbeck Jan 2022

Color-Blind Racial Attitudes In Practicing Dental Hygienists, Emily A. Ludwig, Susan L. Tolle, Jessica R. Suedbeck

Dental Hygiene Faculty Publications

Purpose: Individuals who subscribe to a color-blind racial ideology may not be aware of differences or differential treatment based on race which may be related to racial inequality in the delivery of oral health care. The purpose of this study was to determine color-blind racial attitudes in a convenience sample of clinical dental hygienists.

Methods: A convenience sample of practicing dental hygienists recruited through social media via snowball sampling was invited to participate in this cross-sectional survey study. The Color-Blind Racial Attitudes Scale (CoBRAS), a valid and reliable measuring instrument, was used to determine unawareness of racial attitudes and stereotyping. …


Allied Dental Students' Dvi Learning Outcomes Following A Multimedia Module, Samantha Vest, Brenda Bradshaw, Marsha Voelker, Ann Bruhn, Tara L. Newcomb, Sinjini Sikdar Jan 2022

Allied Dental Students' Dvi Learning Outcomes Following A Multimedia Module, Samantha Vest, Brenda Bradshaw, Marsha Voelker, Ann Bruhn, Tara L. Newcomb, Sinjini Sikdar

College of Health Sciences Posters

This pilot project assessed cognitive and affective learning outcomes of allied dental students following a disaster victim identification (DVI) multi-media learning module.

A convenience sample (n=41) of senior dental hygiene and dental assisting students from two institutions completed an IRB-exempt descriptive pretest/posttest study to assess cognitive and affective changes resulting from exposure to a multimedia DVI learning module of a PowerPoint presentation with audio/video recordings. After completing the learning module, participants were presented with 10 sets of mismatched antemortem (AM) and postmortem (PM) digital bitewing radiographs to test their cognitive ability to indicate identification matches. The pretest/posttest survey was a …


Immediate Loading Of 4 Guided Implants Supporting A Maxillary Overdenture Using A Novaloc Retention System, Doheum Choi Jan 2022

Immediate Loading Of 4 Guided Implants Supporting A Maxillary Overdenture Using A Novaloc Retention System, Doheum Choi

Graduate Theses, Dissertations, and Problem Reports

The purpose of this study was to test the treatment concept of maxillary overdenture retained by four unsplinted implants placed using a flapless guided approach and immediate loading with Novaloc® attachments. Subjects with fully edentulous maxillae received 4 BLX implants (Roxolid®, SLActive®, 3.75mm diameter, Institut Straumann AG, Basel, Switzerland) to support an immediately loaded overdenture. Implants were connected with Novaloc® attachments (Institut Straumann AG, Basel, Switzerland) immediately following surgery if insertion torque (IT) reached 20 N/cm or above. The primary outcome variable was the radiographic bone level change at 6- and 12-months following implant placement. Secondary outcome variables were peri-implant …


Gender Differences In Academic Productivity Within Pediatric Dentistry Departments In Turkey, Basak Kiziltan Eliacik, Meltem Karahan Dec 2021

Gender Differences In Academic Productivity Within Pediatric Dentistry Departments In Turkey, Basak Kiziltan Eliacik, Meltem Karahan

Journal of Dentistry Indonesia

Objective: To investigate the differences in the academic productivity of male and female academicians from the departments of pediatric dentistry in the Faculties of Dentistry in Turkey. Methods: A search was made of international studies indexed in PubMed published up until January 2021 by a total of 241 academicians in the Departments of Pediatric Dentistry of 79 Faculties of Dentistry in Turkey. The total number of international publications for each faculty member was obtained from the institutional websites and thorough searches of PubMed and Web of Science. H-index and the number of citations were established through an advanced search of …


Replacement Of Two Failed Indirect Restorations With Direct Bonded Restorations Using Minimally Invasive Strategy, Citra Kusumasari, Takashi Hatayama, Yasushi Shimada Dec 2021

Replacement Of Two Failed Indirect Restorations With Direct Bonded Restorations Using Minimally Invasive Strategy, Citra Kusumasari, Takashi Hatayama, Yasushi Shimada

Journal of Dentistry Indonesia

Deciding on what treatment (repair or replacement) to provide for a failed indirect restoration can be challenging. Notably, the strength of the residual tooth structure could be improved after replacing the failed indirect restoration using a minimally invasive strategy. Objective: To describe the use of a minimally invasive strategy for the successful clinical replacement of two failed indirect metal restorations with direct composite restorations and the attainment of bonded restoration. Case Report: Case 1. A 52-year-old male patient came to the dental hospital complaining of discomfort when drinking cold beverages and food impaction on the proximal area of the upper …


Ectodermal Dysplasia: A Review, Yasemin Yavuz, Mehmet Sinan Doğan, Myroslav Goncharuk-Khomyn Dec 2021

Ectodermal Dysplasia: A Review, Yasemin Yavuz, Mehmet Sinan Doğan, Myroslav Goncharuk-Khomyn

Makara Journal of Health Research

Background: Ectodermal dysplasia is a complex group of genetic disorders identified through the abnormal development of ectodermal structures. It is a genetic disorder that affects the development or functions of tissues such as the teeth, hair, nails, and sweat glands.

Methods: This review aimed to introduce the outcomes and increase awareness of ectodermal dysplasia reviewing by the literature.

Results: The characteristic features of this disease, including hypodontia, hypohidrosis, and hypotrichosis, have been discussed.

Conclusions: Ectodermal dysplasia is a heterogeneous group of hereditary disorders with similar clinical findings. It leads to the development of tissue malformations and …


Clinical Considerations In Orthodontically Forced Eruption For Restorative Purposes, Grace Huang, Min Yang, Mohannad Qali, Tun-Jan Wang, Chenshuang Li, Yu-Cheng Chang Dec 2021

Clinical Considerations In Orthodontically Forced Eruption For Restorative Purposes, Grace Huang, Min Yang, Mohannad Qali, Tun-Jan Wang, Chenshuang Li, Yu-Cheng Chang

Departmental Papers (Dental)

For restorations on teeth involving invasion of the supracrestal tissue attachment (biological width), as well as for lack of ferrule effect, crown lengthening is required for long-term periodontal health and success of the restoration. In the same fashion, site development is often necessary prior to implant placement in order to provide optimal peri-implant soft and hard tissue architecture conducive to future esthetics and function. Orthodontic extrusion, also known as forced eruption, has been developed and employed clinically to serve the purposes of increasing the clinical crown length, correcting the periodontal defect, and developing the implant site. In order to provide …


Harnessing 3d Collagen Hydrogel-Directed Conversion Of Human Gmscs Into Scp-Like Cells To Generate Functionalized Nerve Conduits, Qunzhou Zhang, Phuong Nguyen, Justin C. Burrell, Jincheng Zeng, Shihong Shi, Rabie M. Shanti, Grace Kulischak, D Kacy Cullen, Anh D. Le Dec 2021

Harnessing 3d Collagen Hydrogel-Directed Conversion Of Human Gmscs Into Scp-Like Cells To Generate Functionalized Nerve Conduits, Qunzhou Zhang, Phuong Nguyen, Justin C. Burrell, Jincheng Zeng, Shihong Shi, Rabie M. Shanti, Grace Kulischak, D Kacy Cullen, Anh D. Le

Departmental Papers (Dental)

Achieving a satisfactory functional recovery after severe peripheral nerve injuries (PNI) remains one of the major clinical challenges despite advances in microsurgical techniques. Nerve autografting is currently the gold standard for the treatment of PNI, but there exist several major limitations. Accumulating evidence has shown that various types of nerve guidance conduits (NGCs) combined with post-natal stem cells as the supportive cells may represent a promising alternative to nerve autografts. In this study, gingiva-derived mesenchymal stem cells (GMSCs) under 3D-culture in soft collagen hydrogel showed significantly increased expression of a panel of genes related to development/differentiation of neural crest stem-like …


An Implantable Human Stem Cell-Derived Tissue-Engineered Rostral Migratory Stream For Directed Neuronal Replacement, John C. O'Donnell, Erin M. Purvis, Kaila Vt Helm, Dayo O. Adewole, Qunzhou Zhang, Anh D. Le, Kacy D. Cullen Dec 2021

An Implantable Human Stem Cell-Derived Tissue-Engineered Rostral Migratory Stream For Directed Neuronal Replacement, John C. O'Donnell, Erin M. Purvis, Kaila Vt Helm, Dayo O. Adewole, Qunzhou Zhang, Anh D. Le, Kacy D. Cullen

Departmental Papers (Dental)

The rostral migratory stream (RMS) facilitates neuroblast migration from the subventricular zone to the olfactory bulb throughout adulthood. Brain lesions attract neuroblast migration out of the RMS, but resultant regeneration is insufficient. Increasing neuroblast migration into lesions has improved recovery in rodent studies. We previously developed techniques for fabricating an astrocyte-based Tissue-Engineered RMS (TE-RMS) intended to redirect endogenous neuroblasts into distal brain lesions for sustained neuronal replacement. Here, we demonstrate that astrocyte-like-cells can be derived from adult human gingiva mesenchymal stem cells and used for TE-RMS fabrication. We report that key proteins enriched in the RMS are enriched in TE-RMSs. …


Genes And Pathways Associated With Skeletal Sagittal Malocclusions: A Systematic Review, Elizabeth Gershater, Chenshuang Li, Pin Ha, Chun-Hsi Chung, Nipul Tanna, Min Zou, Zhong Zheng Dec 2021

Genes And Pathways Associated With Skeletal Sagittal Malocclusions: A Systematic Review, Elizabeth Gershater, Chenshuang Li, Pin Ha, Chun-Hsi Chung, Nipul Tanna, Min Zou, Zhong Zheng

Departmental Papers (Dental)

Skeletal class II and III malocclusions are craniofacial disorders that negatively impact people’s quality of life worldwide. Unfortunately, the growth patterns of skeletal malocclusions and their clinical correction prognoses are difficult to predict largely due to lack of knowledge of their precise etiology. Inspired by the strong inheritance pattern of a specific type of skeletal malocclusion, previous genome-wide association studies (GWAS) were reanalyzed, resulting in the identification of 19 skeletal class II malocclusion-associated and 53 skeletal class III malocclusion-associated genes. Functional enrichment of these genes created a signal pathway atlas in which most of the genes were associated with bone …


The Interleukin-17 (Il-17) Concentration In Saliva Of Patients With Oral Lichen Planus, Mai Talaat Elgendi, Radwa Ragheb Hussien, Ahmed Abdel Aziz Hassan, Olfat Shaker Nov 2021

The Interleukin-17 (Il-17) Concentration In Saliva Of Patients With Oral Lichen Planus, Mai Talaat Elgendi, Radwa Ragheb Hussien, Ahmed Abdel Aziz Hassan, Olfat Shaker

Future Dental Journal

Background: The aim of the present study was to measure the clinical and pain score in these patients and to measure the level of IL-17 in saliva of patients having different forms of Oral lichen planus lesions (OLP).

Subjects and methods: According to sample size calculation, the present study was done on a total of 40 subjects divided into 3 groups Group (I) Twenty patients having erosive/atrophic OLP. Group (II) Ten patients having reticular OLP and Group (III) Ten healthy control patients. Salivary samples were collected from the subjects of the three groups to evaluate the levels of IL-17 using …