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Potential Of Human Deciduous Periodontal Ligament Stem Cells For Use In Hepatic Lineage And Their Exosome Application On Hepatic Injuries, R. Vasanthan Punitha Jan 2020

Potential Of Human Deciduous Periodontal Ligament Stem Cells For Use In Hepatic Lineage And Their Exosome Application On Hepatic Injuries, R. Vasanthan Punitha

Student Works (2020-2029)

Introduction: Human deciduous periodontal ligament stem cells represent as another source of stem cells from the dental origin. These cells were shown to have multi-potential attributes and also self renewing ability. These easily accessible stem cells candidate could also resolve issues concerning ethical and compatability for the use in regenerative purposes. However, their efficiency towards hepatic lineage differentiation has not been addressed so far. Meanwhile, the main contributor for regenerative properties were supposedly mediated by soluble factors and extracellular vesicles such as exosomes secreted by cells. Objectives: The aims of this study are to isolate, characterize and also to investigate …


Dental Therapists' Professional Role And Possible Futures Within The Malaysian Dental Workforce, Zakaria Noor Azhani Jan 2020

Dental Therapists' Professional Role And Possible Futures Within The Malaysian Dental Workforce, Zakaria Noor Azhani

Student Works (2020-2029)

Introduction: The Malaysian Dental Act 2018 has recently superseded the Dental Act 1971. Under this Act, dental therapists are required to register under the Therapist Division, are allowed to work at the private practice, and treat a person up to the age of 18 years old under direct supervision of dentist. It is important to assess the perceptions among essential stakeholders with regards these changes and how it affects the future dental therapists’ workforce. Objectives: To explore the dental therapist future workforce dynamics across sectors (public-private) in Malaysia. Materials and methods: In Phase 1, three parallel quantitative surveys were conducted …


Acculturative Stress, Social Support And Oral Health Related Quality Of Life Among International Graduate Students In Malaysian Public Universities, Ben Ghasheer Hala Fathalla Jan 2020

Acculturative Stress, Social Support And Oral Health Related Quality Of Life Among International Graduate Students In Malaysian Public Universities, Ben Ghasheer Hala Fathalla

Student Works (2020-2029)

Background: Oral health related quality of life (OHRQoL) reflects the impact of the oral condition on physical, social, and psychological functioning and well-being from an individual’s perspective. It is an important health outcome that is influenced by several factors which together are known as the determinants of health. Psychosocial factors are among many other factors that have a crucial role in shaping oral health. Understanding their role in relation to diminished oral health has gained more interest in recent years since such factors could serve as points of intervention for new oral health promotion strategies. Aim: This study aimed to …


Identification Of Potential Biomarkers Of Oral Squamous Cell Carcinoma Using Integrated Proteomics And Glycoproteomics And Glycoproteomics Analyses, Yin Ling Wong Jan 2020

Identification Of Potential Biomarkers Of Oral Squamous Cell Carcinoma Using Integrated Proteomics And Glycoproteomics And Glycoproteomics Analyses, Yin Ling Wong

Student Works (2020-2029)

Oral cancer is one of the major health concerns worldwide. The 5-year survival rate of oral squamous cell carcinoma (OSCC) has remained at approximately 50% over the past decades. Most OSCCs are diagnosed at an advanced stage due to the delay in diagnosis, suggesting an imperative need in identifying reliable biomarkers to improve the diagnosis, prognosis, and treatment of OSCC. This study aimed to identify potential biomarkers that are involved in the development and progression of OSCC using integrated proteomics and glycoproteomics analyses. Proteomics analysis was performed on serum samples of 10 patients with oral potentially malignant disorder (OPMD), 40 …