Medicine and Health Sciences Commons^™

Efficacy Of Social Cognitive Interventions On Improving Social Participation In Children With Autism Spectrum Disorder, T. Book, A. Ching, A. Pirilli, J. Salem, C. Taylor, S. Valverde, M. Ferraro, M. C. Potvin

Student Papers, Posters & Projects

Social cognitive training programs, developed primarily by mental health and educational professionals to teach social skills to children with ASD, may have the potential for implementation in the field of occupational therapy to support social participation among this population.

This current systematic review was conducted to examine the efficacy of social cognitive interventions to improve social participation in children with ASD

A Systematic Review Of The Efficacy Of Cognitive Stimulation Therapy (Cst) On Quality Of Life In Persons With Dementia, R. Babiarz, B. Haden, S. Karlin, J. Mark, A. Williams, M. Ferraro, M. C. Potvin

Student Papers, Posters & Projects

Quality of life (QoL) is an established outcome measure of patients with dementia and is strongly influenced by an individual's environment and mood. While there are many outcomes that can be examined with Cognitive stimulation therapy (CST) interventions, this systematic review focused on quality of life.

Efficacy Of Cognitive And Metacognitive Interventions On Executive Functioning Post Traumatic Brain Injury To Enhance Occupational Performance, C. Blaker, A. Curry, S. Dickerson, K. Johnson, M. Santangelo, A. Thomas Tasman, M. Ferraro, Marie-Christine Potvin

Student Papers, Posters & Projects

Cognitive rehabilitation (CR) is proposed as an effective intervention for individuals post Traumatic Brain Injury (TBI), by addressing cognitive function through remediating skills and practicing new compensatory skills. While there is considerable research, including systematic reviews that explore cognitive interventions post TBI, more research is needed in which occupational performance is the primary outcome of cognitive intervention. This current systematic review aims to synthesize the current body of evidence available on how using CR techniques to address executive functioning impact occupational performance in individuals who sustained a mild or moderate TBI.

The Perils Of Recreational Marijuana Use: Relationships With Mental Health Among Emergency Department Patients, Catherine A. Marco, John Paul Detherage Iii, Ashley Lafountain, Megan Hanna, Justin Anderson, Rachel Rhee, Jacqueline Ziegman, Dennis Mann

Emergency Medicine Faculty Publications

Abstract Introduction Marijuana is a commonly used drug in the United States. Many states have legalized the recreational use of marijuana. The effects of marijuana on mental health are unknown. Methods In this prospective survey study, eligible participants included ED patients age 18 and older, who had ever used recreational marijuana. A survey instrument was developed, piloted, and revised. Data collected included reasons for marijuana use, marijuana's perceived effectiveness, and history of mental health conditions, including depression, anxiety, and suicidal thoughts. Results Among 303 participants (86% response rate), the median age of first marijuana use was 16 ([IQR 14, 19], …

A 10-Year Follow-Up Study Of Sex Inclusion In The Biological Sciences, Nicole C. Woitowich, Annaliese K. Beery, Teresa K. Woodruff

Neuroscience: Faculty Publications

In 2016, to address the historical overrepresentation of male subjects in biomedical research, the US National Institutes of Health implemented a policy requiring investigators to consider sex as a biological variable. In order to assess the impact of this policy, we conducted a bibliometric analysis across nine biological disciplines for papers published in 34 journals in 2019, and compared our results with those of a similar study carried out by Beery and Zucker in 2009. There was a significant increase in the proportion of studies that included both sexes across all nine disciplines, but in eight of the disciplines there …

Stress In Groups: Lessons From Non-Traditional Rodent Species And Housing Models, Annaliese K. Beery, Melissa M. Holmes, Won Lee, James P. Curley

Neuroscience: Faculty Publications

A major feature of life in groups is that individuals experience social stressors of varying intensity and type. Social stress can have profound effects on health, social behavior, and ongoing relationships. Relationships can also buffer the experience of exogenous stressors. Social stress has most commonly been investigated in dyadic contexts in mice and rats that produce intense stress. Here we review findings from studies of diverse rodents and non-traditional group housing paradigms, focusing on laboratory studies of mice and rats housed in visible burrow systems, prairie and meadow voles, and mole-rats. We argue that the use of methods informed by …

Older Adults’ Perspectives On Occupational Supports In Alternative Housing Communities, A'Via Coleman, Lisa Goolsby, Kara Lurvey, Elizabeth Von Achen, Heather Veverica

Older Adult

The Problem: Many older adults in the United States wish to age in place but may find their current living environment is not suitable as they age. Alternative housing supports may improve the ability of older adults to live in their own home and community safely while performing necessary occupations.

The Resolution: Alternative housing communities offer a variety of supports that older adults value having access to, even if they are not always utilized including transportation, social interaction, volunteer opportunities, home maintenance, an accessible location, and the togetherness of community.

An Exploration Of Leadership Qualities Demonstrated During Level Ii Fieldwork, Amy Maurer, Summer Besteman, Jessica Mooney, Katelyn Campbell

Education

Background. Occupational therapy (OT) students are expected to demonstrate leadership qualities throughout their Level II Fieldwork experiences; however, it has been reported that students lack this quality. The purpose of this project was to identify the leadership characteristics that master’s-level OT students demonstrate and develop during their Level II Fieldwork experiences.

Method. This study utilized an online survey tool, Qualtrics, to understand the perceptions of Fieldwork Educators (FWEds) who have taken a Level II Fieldwork student within the past five years. A code-recode procedure was used to analyze open-ended questions. The frequency and mode of responses were used to report …

Is It Cool To Juul? A Case Of Vaping Induced Lung Injury, Natasha Palmer, Jacqueline Storer, Yaasen Bhutta, Luis A. Murillo

Reading Hospital Family Medicine Residency

“Vaping” is the inhalation of an aerosolized substance produced through heating a solution that typically contains nicotine, cannabis, or other substances. There are many products available commercially used as devices for vaping such as the electronic cigarette, vape, or “JUUL.” Vaping has become especially popular among teens and young adults likely due to marketing these devices as “safe” when compared to the traditional cigarette, and there are a wide variety of flavors.

Covid-19 Vulnerability Among People Who Use Drugs: Recommendations For Global Public Health Programmes And Policies, Ian W. Holloway, Anne C. Spaulding, Ayako Miyashita Ochoa, Laura A. Randall, Adrian R. King, The Hbou Study Team, Paula M. Frew

School of Public Health Faculty Research

No abstract provided.

Agrammatism And Paragrammatism: A Cortical Double Dissociation Revealed By Lesion-Symptom Mapping, William Matchin, Alexandra Basilakos, Brielle C. Stark, Dirk B. Den Ouden, Fridolin Gross, Gregory Hickok

Communication Sciences and Disorders Faculty Articles and Research

The fundamental distinction of grammatical deficits in aphasia, agrammatism and paragrammatism, was made over a century ago. However, the extent to which the agrammatism/paragrammatism distinction exists independently of differences in speech fluency has not clearly been investigated. Despite much research on agrammatism, the lesion correlates of paragrammatism are essentially unknown. Lesion-symptom mapping was used to investigate the degree to which the lesion correlates of agrammatism and paragrammatism overlap or dissociate. Four expert raters assessed videos of 53 right-handed patients with aphasia following chronic left-hemisphere stroke retelling the Cinderella story. Consensus discussion determined each subject’s classification with respect to grammatical deficits …

Prediction Of Trimethoprim/Sulfamethoxazole Resistance In Community-Onset Urinary Tract Infections, Madeline Demarsh, P Brandon Bookstaver, Caroline Gordon, Juanne Lim, Nicole Griffith, Nicole K. Bookstaver, Julie Ann Justo, Joseph Kohn, Majdi N. Al-Hasan

Faculty Publications

OBJECTIVES: This study aimed to predict trimethoprim/sulfamethoxazole (SXT) resistance in patients with community-onset urinary tract infection (UTI) due to Enterobacteriaceae based on patient-specific risk factors. METHODS: This was a retrospective case-control study in Prisma Health facilities in central South Carolina, USA, including three community hospitals, affiliated emergency departments and ambulatory clinics, including adult patients with community-onset UTI due to Enterobacteriaceae (1 April 2015 to 29 February 2016). Multivariate logistic regression was used to examine risk factors for SXT resistance. RESULTS: Among 351 unique patients with community-onset UTI, 71 (20.2%) had SXT-resistant Enterobacteriaceae urinary isolates. Overall, median age was 64 years …

Reliability And Validity Of Watch: Warwick Assessment Instrument For Clinical Teaching, Sonia Ijaz Haider, Khalid Masood Gondol, Muhammed Tariq, Muhammad Furqan Bari, Iqbal Azam Syed

Department for Educational Development

Objective: To determine the reliability, validity, feasibility, acceptability and perceived educational impact of WATCH: Warwick Assessment insTrument for Clinical teacHing among doctors in Pakistan.
Study design: Cross-sectional research study.
Place and duration of study: The College of Physicians and Surgeons, Pakistan, from September 2018 to August 2019.
Methodology: Postgraduate trainees were asked to rate the clinical teaching sessions, using WATCH, which consists of 15 items. Percentage was used to calculate gender and participation from different specialties. Inter-item correlations of 15 items with individual mean scores, standard deviations and Cronbach's Alpha were reported, including Friedman test, in order to observe the …

Mechanisms Of Bak Activation In The Initiation Of Mitochondrial Apoptosis, Geetika Singh

Theses and Dissertations (ETD)

Mitochondrial apoptosis is crucial for normal mammalian development and adult homeostasis being regulated by B-Cell Lymphoma-2 (BCL-2) proteins. Deregulation of BCL-2 proteins form the basis for myriad of human pathologies including cancer and autoimmune diseases. Therefore, BCL-2 proteins are considered key therapeutic targets. BCL-2 homologous antagonist/killer (BAK) is an effector of outer mitochondrial membrane (OMM) pemeabilization or mitochondrial poration. Despite progress in understanding BAK-mediated mitochondrial poration, the underlying multi-step mechanism is not clearly defined. Here, we provide mechanistic details on the early steps in this process related to BAK activation, including transient direct activation and autoactivation. We demonstrate for the …

Provision Of Mental Health Services By Critical Access Hospital-Based Rural Health Clinics, John A. Gale Ms, Zachariah T. Croll Mph, Nathan First Lcsw, Msw, Ma, Sara Kahn-Troster Mph

Rural Health Clinics

Residents of rural communities face longstanding access barriers to mental health (MH) services due to chronic shortages of specialty MH providers, long travel distances to services, increased likelihood of being uninsured or under-insured, limited choice of providers, and high rates of stigma. As a result, rural residents rely more heavily on primary care providers and local acute care hospitals to meet their MH needs than do urban residents. This reality highlights the importance of integrating primary care and MH services to improve access to needed care in rural communities. Critical Access Hospitals (CAHs) are ideally positioned to help meet rural …

Comparison Of Dna Extracted From Pediatric Saliva, Gingival Crevicular Fluid And Site-Specific Biofilm Samples, Jason Emett, Roxanne David, Jaydene Mcdaniel, Steven Mcdaniel, Karl Kingsley

Dental Medicine Faculty Research

(1) Introduction: Due to the non-invasive nature of saliva, many methods have been used to isolate and collect DNA from saliva samples for microbial screening. Many oral microbes also inhabit the oral biofilm, which may represent significantly different microbial constituents that may contribute to oral health and disease, including caries and periodontal disorders. Moreover, the biofilm may vary within the same patient at different sites. Few studies have evaluated the comparison between DNA isolated from saliva and DNA from site-specific biofilm, with virtually no studies addressing this analysis among pediatric patients. (2) Methods: An existing repository of paper point derived …

Occupational Therapy As Part Of A Team-Based Approach In Primary Care Settings, Lydia Royeen

Dissertations

The purpose of this project was to study issues related to occupational therapists integrating into primary care settings, as part of a team-based approach and to best meet the needs of the clients.

This is a mixed methods study that examined quantitative and qualitative data for members of the primary care team and occupational therapists working in primary care clinics. The Team Climate Inventory-14 (Kivimaki & Elovainio, 1999) was selected as the quantitative measure because it examines themes related to team functioning, which include vision, participative safety, task orientation, and mutual support. Participants completed a semi-structured interview that examined themes …

Diagnostic Accuracy Of Cardiac Magnetic Resonance Versus Fractional Flow Reserve: A Systematic Review And Meta-Analysis., Waqas Ullah, Sohaib Roomi, Hafez M. Abdullah, Maryam Mukhtar, Zain Ali, Ping Ye, Donald C. Haas, Vincent M. Figueredo

Abington Jefferson Health Papers

Background: Fractional flow reserve (FFR) is considered the gold standard for diagnosis of coronary artery disease (CAD). Stress Cardiac magnetic resonance (SCMR) has been recently gaining traction as a non-invasive alternative to FFR.

Methods: Studies comparing the diagnostic accuracy of SCMR versus FFR were identified and analyzed using Review Manager (RevMan) 5.3 and Stata software.

Results: A total of 28 studies, comprising 2,387 patients, were included. The pooled sensitivity and specificity for SCMR were 86% and 86% at the patient level, and 82% and 88% at the vessel level, respectively. When the patient-level data were stratified based on the FFR …

The Reproductive Health And Academic Impact Of The New York City School-Based Health Center Reproductive Health Project For Adolescents, Michelle Silverio

Dissertations and Theses

Background: Gaining an understanding of how school reproductive health policies impact adolescent sexual health and academic outcomes is a public health priority in the United States (U.S.) since it has the highest rates of adolescent pregnancy and sexually transmitted infections among developed nations. Adolescence is a critical developmental period and influences in this period affect reproductive health and social well-being over a person’s entire lifespan. Almost all adolescents spend the majority of their time in school settings; therefore local school reproductive health policies may have substantial lifetime impacts. Policies such as providing comprehensive sexual health education and contraceptive access in …

Development Of A Hospital Readmission Reduction Program For Patients Discharged To Skilled Nursing Facilities: An Application Of Artificial Intelligence And Machine Learning Techniques, Anna Stachel

Dissertations and Theses

Background

Hospital readmissions within 30 days after discharge have drawn national policy attention as they are a reflection of suboptimal patient care. Readmissions are costly, accounting for more than $17 billion in potentially avoidable Medicare expenditures - nearly 78% of readmissions may be avoidable. Rich electronic data from medical records, growing computing capacities, and open source machine learning algorithms offer new opportunities to predict patients at high risk for readmission and prevent readmission through focused interventions. Prediction models might also serve to provide a more nuanced context of patient characteristics that lead to variations in readmission rates. Furthermore, transitional care …

Methods For Improving Quality Of Care Within Acute And Post-Acute Settings, Kelly L. Vankoevering

Dissertations

According to the Centers for Medicare and Medicaid (CMS), over the next 7 years, U.S. national healthcare spending is projected to grow at an average of 5.7% per year, up from 4.8% in 2019. Additionally, personal health care cost is expected to increase by 2.7% per year. As a result, there have been increased efforts among healthcare systems and hospital organizations to improve quality of care while decreasing healthcare cost. The research reported in this dissertation builds upon the existing literature regarding interventions to improve hospital performance and quality metrics. Two of the most researched and effective strategies for improving …

Recent Advances In Stimuli-Responsive Drug Release And Targeting Concepts Using Mesoporous Silica Nanoparticles, Ghada G. Abdo, Moustafa M. Zagho, Ashraf Khalil

Faculty Publications

Being a developed and promising approach, nanotechnology has attracted a lot of attention in biomedical and pharmaceutical therapy applications. Among nanostructured materials, mesoporous silica nanoparticles (MSNs) are effectively used as nanocarriers for drug delivery systems. MSNs can be tailored-designed by different synthetic techniques. Their morphological characteristics dictate the type of application of such materials. Recently, polymer-based materials have been employed to functionalize the MSNs surface. These modified nanocarriers are loaded with the drug and can unload their “cargo” upon exposure to either endogenous or exogenous types of stimuli. In this study, different targeting concepts, including passive, active, vascular, nuclear, and …

Comparison Of Staphylococcus Aureus Nasal Carriage By Patients And Healthcare Workers In Selected Dialysis Centers In Nairobi And Neighbouring Counties, Enock Serem

Master of Medicine in Clinical Pathology

Background: Staphylococcus aureus (S. aureus) is a significant pathogen that causes both community and hospital acquired infections. The burden of S. aureus morbidity and mortality is disproportionately high in patients with end stage kidney disease undergoing dialysis. With the rising prevalence of non-communicable diseases leading to end stage renal disease and dialysis, the impact of S. aureus infections is projected to rise. Knowledge of nasal carriage of S. aureus and their antibiotic resistance profiles is essential in improving patient care through planning of infection prevention and control strategies as well as formulating appropriate empiric antibiotic guidelines. The aim of this …

Axillary Artery Pseudoaneurysm Following Percutaneous Transaxillary Access For Impella Device Placement During Percutaneous Coronary Intervention, Anas A. Alharbi, Fahad S. Alqahtani, Peter Farjo, Jason A. Moreland

Internal Medicine Faculty Publications

Percutaneous transaxillary access is currently considered an acceptable alternative to transfemoral approach for large-bore access, especially in the setting of hostile iliofemoral arteries. Few published reports exist concerning complications of upper extremity access. We describe development of an axillary artery pseudoaneurysm and its management following transaxillary access. (Level of Difficulty: Advanced.)

Non-Invasive Peripheral Venous And Arterial Line Air Detector For Embolization Prevention, Alexandria Kwong, Kevin Shu, Dylan Meinster

Biomedical Engineering

The scope of this project includes designing a non-invasive bubble detector for peripheral venous and arterial lines. For minimally invasive cardiac procedures, arterial and venous access is necessary for these procedures as is constant flow through the tubing to prevent clotting and to administer drugs. Air bubbles are common in these lines and can be consequential if enough air is introduced into the human system. Air embolisms are the most common and relevant issues during these procedures. The goal of this device is to create an attachable detector for air bubbles in saline that can also terminate flow and alert …

Insight Into Covid-19 Responses And Initiatives From Pakistan, Salima Farooq, Sonia Ijaz Haider, Saima Sachwani, Yasmin Parpio

School of Nursing & Midwifery

The coronavirus pandemic is a rapidly evolving outbreak that has tremendously distressed people worldwide. The paper aims to present some key rapid responses and initiatives to COVID-19 undertaken in Pakistan. The information has been gathered by reviewing material and documents pertinent to COVID-19 in the context of Pakistan. The incidences of COVID-19 cases are gradually increasing; however, the case fatality rate is relatively lower in Pakistan as compared to developed countries. The government has taken massive actions, in terms of lockdowns, quarantine homes, testing facilities, closure of schools, and mass gatherings at places, to combat COVID-19. However, the measures seem …

Mindfulness For Stress Reduction: Qualitative Analysis Of Perceptions From College Students And Mindfulness Instructors, Beth Marie Merlo

Master's Theses

Although mindfulness interventions with college students have yield positive results, many students are not continuing to engage after the interventions. This may be because very little research has been done to investigate the health behavior beliefs of college students in regard to mindfulness for stress reduction. The purpose of this investigation was to identify the most influential components of the Integrated Behavioral Model (IBM) that potentially assist with predicting college student participation in mindfulness activities for stress reduction. Interviews, informed by the IBM, were conducted with 20 current college students and 5 current mindfulness instructors working with college students. The …

Covid-19: The New Corona Virus Upsetting Our World, Rafat Jan, Edwin Van Teijlingen

Journal of Asian Midwives (JAM)

No abstract provided.

Reflections: Bravo Breastfeeding Mother! A Covid Positive Mother And Midwifery Instinct, Rafat Jan

Journal of Asian Midwives (JAM)

No abstract provided.

Developing And Piloting A Midwifery Audit Tool In Bangladesh’S Upazila Health Complexes (Uhcs), Achiya Khatun, Mahfuja Aktar Jhumu, Sarah Gregson, Joy Kemp

Journal of Asian Midwives (JAM)

Midwifery is a new profession in Bangladesh. Diploma-prepared midwives were first deployed in 2018. Recent studies suggest that newly qualified midwives in Bangladesh may not be able to fully perform their midwifery role due to a number of complex factors. This paper describes a pilot study of a midwifery audit undertaken in 2019 by the Bangladesh Midwifery Society, supported by the Royal College of Midwives. These two organisations are in a formal twinning partnership funded by UNFPA Bangladesh with support from UK-Aid, Sweden and Canada. The audit was successful in improving the quality of midwifery care and addressing health system …