Medicine and Health Sciences Commons^™

Gait Entrainment In Coupled Oscillator Systems: Clarifying The Role Of Energy Optimization In Human Walking, Ryan T. Schroeder

Theses: Doctorates and Masters

Empirical evidence suggests that parameters of human gait (e.g. step frequency, step length) tend to minimize energy expenditure. However, it is unclear if individuals can adapt to dynamic environments in real time, i.e. continuously optimize energy expenditure, and to what extent. Two coupled oscillator systems were used to test the learned interactions of individuals within dynamic environments: (1) experienced farmworkers carrying oscillating loads on a flexible bamboo pole and (2) individuals walking on a treadmill while strapped to a mechatronics oscillator system providing periodic forces to the body. Reductionist trajectory optimization models predicted energy-minimizing gait interactions within the coupled oscillator …

Quantifying The Heterogeneity Of The Immunoglobulin G N-Glycome In An Ageing Australian Population: The Busselton Healthy Ageing Study, Alyce Russell

Theses: Doctorates and Masters

The use of immunoglobulin G N-glycomics to study chronic non-communicable disorders and other complex phenotypes emerged following the Human Genome Project. The consortium discovered that most phenotypes were too complex to be explained by genetics alone. Thus, the biological importance of epigenetics was recognised; heritable modifications to gene expression rather than the genome itself. Nglycosylation is a form of epigenetic regulation known as a post-translational modification. It stabilises the immunoglobulin G structure and alters downstream responses elicited by the antibody and is extensively studied as a candidate biomarker in the post-genomic era.

The N-glycosylation of immunoglobulin G itself is complex, …

Appraisal Of Free Online Symptom Checkers And Applications For Self-Diagnosis And Triage: An Australian Evaluation, Michella Gaye Hill

Theses: Doctorates and Masters

The internet has impacted society and changed the way companies and individuals operate on a daily basis. Seeking information online via computer or mobile device is common practice. The phrase ‘Google it’ is now part of modern vernacular and is a resource increasingly utilised by young and old alike. Around 80% of Australian’s search health-related information online as it is convenient, cheap, and available 24/7. Symptom checkers are one tool used by consumers to investigate their health issues. Symptom checkers are automated online programs which use computerised algorithms, asking a series of questions to help determine a potential diagnosis and/or …

Improving Sprint Performance In Road Cycling: The Forward Standing Sprint Position, Paul Franciscus Johannes Merkes

Theses: Doctorates and Masters

The majority of road cycling races finish with a sprint and as such sprints are a key determinant of success. Surprisingly, the scientific literature on this specific topic is scarce, with limited to few studies describing the characteristics of road cycling sprinters and the demands of road sprinting. Cyclists’ sprinting velocity, which is mostly influenced by power output and aerodynamic drag (CdA) is critical to performance outcomes. However, to date, there is very limited research specifically examining how to maximise road sprint velocity. Thus, the overall objective of the four studies outlined in this thesis was to manipulate CdA, physiology, …

Determining Ground-Level Composition And Concentration Of Particulate Matter Across Regional Areas Using The Himawari-8 Satellite, Miles Sowden

Theses: Doctorates and Masters

Speciated ground-level aerosol concentrations are required to understand and mitigate health impacts from dust storms, wildfires and other aerosol emissions. Globally, surface monitoring is limited due to cost and infrastructure demands. While remote sensing can help estimate respirable (i.e. ground level) concentrations, current observations are restricted by inadequate spatiotemporal resolution, uncertainty in aerosol type, particle size, and vertical profile. One key issue with current remote sensing datasets is that they are derived from reflectances observed by polar orbiting imagers, which means that aerosol is only derived during the daytime, and only once or twice per day.

Sub-hourly, infrared (IR), geostationary …

The Effects Of Environmental Temperature On High-Intensity Interval Training, Jason R. Boynton

Theses: Doctorates and Masters

Endurance athletes typically spend the large majority of training (> 70%) at low intensities (i.e. below lactate threshold) coupled with short and intermittent bouts of high-intensity exercise or interval training (HIIT). Despite HIIT being a relatively small part of training in terms of duration, it has a substantial effect on the adaptations to endurance training. While it is well-established endurance exercise performance is affected in both hot and cold environmental conditions, the effect ambient temperature (TA; frequently referred to as environmental temperature) has on HIIT as performed by an endurance athlete population is not well understood. Therefore, the overall purpose …

No Happy Accident: Defining The Factors Contributing To The Success And Longevity Of A Long-Running Community Engagement Program, Jennifer Irvine

Theses: Doctorates and Masters

The Kalamunda Community Learning Centre (‘the Centre’) was established in 1977 by a group of four women, following their attendance at a conference held by the Women’s Electoral Lobby. Originally named the Kalamunda Women’s Learning Centre, it was established with a charter to improve the status of women, whilst providing a place to alleviate isolation and boredom for ‘stay at home’ mothers. Through its structure, underpinned by feminist ideology, the Centre also provided a place for women to practice skills that would build their confidence with respect to returning to the workforce. From its beginnings with a predominant focus on …

Semi-Automated Segmentation Of The Lateral Periventricular Regions Using Diffusion Magnetic Resonance Imaging, Albert M Isaacs, Rowland H Han, Christopher D Smyser, David D Limbrick, Joshua S Shimony

2020-Current year OA Pubs

The lateral ventricular perimeter (LVP) of the brain is a critical region because in addition to housing neural stem cells required for brain development, it facilitates cerebrospinal fluid (CSF) bulk flow and functions as a blood-CSF barrier to protect periventricular white matter (PVWM) and other adjacent regions from injurious toxins. LVP injury is common, particularly among preterm infants who sustain intraventricular hemorrhage or post hemorrhagic hydrocephalus and has been associated with poor neurological outcomes. Assessment of the LVP with diffusion MRI has been challenging, primarily due to issues with partial volume artifacts since the LVP region is in close proximity …

Physician Attitudes Towards-And Adoption Of-Mobile Health, Tracie Kong, Mary Morgan Scott, Yang Li, Cynthia Wichelman

2020-Current year OA Pubs

OBJECTIVE: Smartphone apps and mobile devices are an emerging method of healthcare data collection. This study sought to understand how physicians currently view mobile health (mHealth) technologies and use them in patient care.

METHODS: A total of 186 physicians affiliated with Washington University School of Medicine in St. Louis, Missouri, USA completed a survey in 2016 regarding their current implementation of mHealth technologies for patient care and support for further development.

RESULTS: More than half of respondents were willing to discuss health apps and mobile devices with patients. However, most were not currently recommending them to patients. Apps/devices that encouraged …

How Do Subjective Health Literacy Measures Work In Young Adults? Specifying "Online" Or "Paper-Based" Forms Impacts Results, Mary C Politi, Courtney M Goodwin, Kimberly A Kaphingst, Xuechen Wang, Angela Fagerlin, Lindsay N Fuzzell, Sydney E Philpott-Streiff

2020-Current year OA Pubs

No abstract provided.

2019 Hrs/Ehra/Aphrs/Lahrs Expert Consensus Statement On Catheter Ablation Of Ventricular Arrhythmias, Edmond M Cronin, Phillip Cuculich, Et Al.

2020-Current year OA Pubs

Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to sustained ventricular tachycardia and fibrillation. Rapid developments have taken place over the past decade in our understanding of these arrhythmias and in our ability to diagnose and treat them. The field of catheter ablation has progressed with the development of new methods and tools, and with the publication of large clinical trials. Therefore, global cardiac electrophysiology professional societies undertook to outline recommendations and best practices for these procedures in a document that will update and replace the …

Mechanisms Underpinning An Improvement In Dynamic Muscle Force Production Following A High-Intensity Warm-Up, Cody J. Wilson

Theses: Doctorates and Masters

The present research explored the mechanisms underpinning the enhancement of voluntary knee extensor torque after (1) extensive task-specific practice, and then (2) brief, intense warm-up exercise (conditioning activity; CA) as part of a complete warm-up routine. The same warm-up was completed in two Experiments (detailed below). In Experiment 1, voluntary (180⁰·s-1; T180) and electrically-evoked (isometric) knee extensor torques and electromyogram (EMG) and muscle temperature (Tm) data were recorded before and after (1) extensive task-specific practice where peak voluntary knee extensor performance was achieved, and (2) two isokinetic CAs matched for total concentric contraction time (CA60: 5 repetitions at 60⁰·s-1 vs. …

Drug Users’ Experiences Of A Residential Rehabilitation Program In Western Australia: A Thematic Analysis Of Drug Users Lived Experiences, Michelle Fullam

Theses: Doctorates and Masters

In the last decade, there has been a marked increase in the awareness of drug use and drug-related crime in Australia. As a result, the demand for drug treatment services has increased and 14 recognised government-funded services are now available in Western Australia (WA). The goal of these services is to reduce drug use through full-time intensive programs that are usually residential. This type of drug treatment has been shown to be effective in reducing drug use and promoting pro-social lives post-treatment. However, little is known of the experiences of participants in this type of treatment in WA. As such, …

Exercise And Nutrition Induced Weight Loss For Prostate Cancer Patients, Rebekah Louise Wilson

Theses: Doctorates and Masters

This thesis encompasses six main chapters - two reviews and four experimental chapters, in addition to a general introduction and discussion.

Review 1 (Chapter 2) is a discussion of the negative impact of obesity on prostate cancer prognosis and common prostate cancer treatments.

Review 2 (Chapter 3) is an evaluation of the current literature examining prostate cancer patients receiving androgen deprivation therapy (ADT) and how exercise and nutrition interventions can be used to induce fat loss, while preserving or improving lean mass.

Study 1 (Chapter 4) is an examination of the efficacy of a weight loss program in altering body …

The Importance Of Telehealth In The Implementation Of Best Practice In Paediatric Burn Management By Non-Burn Specialist Clinicians, Tania Mcwilliams

Theses: Doctorates and Masters

Introduction: Burns are a leading cause of injury worldwide, yet the initial assessment and management of patients following burn injury is often performed by non-burn specialist clinicians. Using the Gilbert Behaviour Engineering Model as a framework, strategies were introduced to support these clinicians. A better understanding was needed, however, of the effectiveness of these strategies, and the experiences of clinicians who provide this initial care.

Aims: This study aims to contribute new knowledge related to paediatric burn care through the evaluation of a state-wide burns telehealth program in Western Australia; specifically, develop a deeper and more relevant understanding of a …

Injury Surveillance In Community Cricket And The Exploration Of Insurance Claims Systems, Geordie Mcleod

Theses: Doctorates and Masters

The aims of this industry funded PhD thesis were 1) To understand the injury causes, trends and burden in community cricket and 2) To examine the Cricket Australia National Club Risk Protection Program (NCRPP) insurance scheme for suitability as an injury surveillance tool for community cricket.

This thesis sought to identify and understand the injury profile of community cricketers through existing literature and injury datasets, being, Victorian Injury Surveillance Unit (VISU) hospital data, Accident Compensation Corporation (ACC) and NCRPP insurance claims data. This thesis also undertook a novel assessment of data validity and completeness from various sources, against industry standards …

Barriers To Ghanaian Midwives’ Ability To Provide Quality Care: A Glaserian Grounded Theory Study, Yakubu Ismaila

Theses: Doctorates and Masters

The midwifery model of care that promotes the employment of trained and regulated midwives for the provision of maternal and neonatal care has been found to be beneficial, especially in Low and Middle-Income Countries that have high maternal and neonatal mortalities. Midwives in those setting are however, facing a myriad of barriers which negatively affect their ability to provide optimal care. Although Ghana is implementing the midwifery model of care, maternal and neonatal mortality remains high in the country. Little is known from the point of view of midwives, who are the primary providers of maternal and neonatal care, about …

Improving Processes For Implementing Evidence-Based Practice In Midwifery: Development Of An Etool(Kit) For Midwives, Annemarie June De Leo

Theses: Doctorates and Masters

Evidence-based practice (EBP) is well-established as the gold standard for service delivery of quality healthcare around the world, yet there remains a significant gap between best available evidence and its everyday use in maternity services. The numerous benefits of EBP are therefore never realised and although a considerable body of knowledge has evolved on how to promote the uptake of new EBPs, little is known about midwives’ experience of implementing EBP or leading practice change projects in clinical areas.

The aim of this study was to work collaboratively with midwives towards the co-development of an evidence implementation resource, designed to …