Medicine and Health Sciences Commons^™

Prevalence Of Vitamin D Deficiency In Exclusively Breastfed Infants At A Tertiary Healthcare Facility In Nairobi, Kenya, Nusrat Abubakar, Rose Kamenwa, Mary Limbe, Mitchel Otieno Okumu, William Macharia

Paediatrics and Child Health, East Africa

Objective: To determine the prevalence of vitamin D deficiency (VDD) in exclusively breastfed infants at the Aga Khan University Hospital Nairobi, Kenya (AKUHN). The relationships between 25-hydroxyvitamin D; 25OHD, parathyroid hormone (PTH), maternal vitamin D supplementation, and sunlight exposure were also determined.

Subjects and methods: Blood from 98 infants was assayed for 25OHD, calcium, phosphate, and PTH. Socio-demographic and clinical characteristics were analyzed using descriptive statistics and inferential analysis (p < 0.05).

Results: The prevalence of VDD (25OHD <12 ng/mL), vitamin D insufficiency (VDI, 25OHD 12-20 ng/mL) and vitamin D sufficiency (VDS, 25OHD >20 ng/mL) was 11.2% (95% CI 8.0%-14.4%), 12.2% (95% CI 8.9%-15.5%), and 76.5% (95% CI 72.3%-80.8%) respectively. There was no difference in the …

A Case Of Pott's Disease: Typical Presentation Of An Uncommon Disease In The United States, Neha Patel, Ravi Patel, Marek Krysztofiak, K V. Sundaresh

West Florida Division GME Research Day 2020

Pott’s disease (PD), also known as tuberculosis spondylitis, is a rare disease of the spine which is typically caused by extraspinal infection. The basic lesion in Pott's disease is a combination of osteomyelitis and arthritis, usually affecting more than one vertebra. The anterior aspect of the vertebral body adjacent to the subchondral plate is commonly involved. Spinal TB can include any of the following: progressive bone destruction leading to vertebral collapse and kyphosis, cold abscess formation (due to extension of infection into adjacent ligaments and soft tissues), spinal canal narrowing by abscesses, granulation tissue or direct dural invasionresulting in spinal …

Pasteurella Multocida Bacteremia Secondary To Multiple Cat Scratches, Charles Boadu, Andrea Hernandez, Bassem Zeidan, John T. Young, Johnathan Frunzi

West Florida Division GME Research Day 2020

Pasteurella multocida(P. multocida)is part of the normal gastrointestinal and upper respiratory flora of domestic and wild animals such as dogs, cats, rabbits, opossums, boars, tigers, lions and horses ^{(1, 2)}. Transmission of P. multocidais usually through scratches and bites leading to infections of the soft tissue and skin ^(3,4). P. multocida bacteremia is rare, but occurs in individuals with major risk factors including chronic pulmonary disease, diabetes mellitus, end state renal disease (ESRD), and an immunocompromised state ^(3,4). Non traumatic infections of P. multocida in immunocompromised individuals,are more likely to require care in the intensive care unit …

Kounis Syndrome, Charles Doerner, Mark Sawh, Tamer A. Amer, Konstantinos Marmagkiolis

West Florida Division GME Research Day 2020

Kounis syndrome, also known as allergic vasospastic angina, is a type of acute coronary syndrome caused by an allergic reaction or immune response to a substance.[1] It is essentially an “allergic angina” which is believed to be caused by mast cell activation and release of cytokines and histamine causing spasm of the artery leading to acute coronary syndrome and acute myocardial infarction. Stress cardiomyopathy (Takotsubo syndrome), which predominantly affects post-menopausal women, may also occur in anaphylaxis where transient ventricular dysfunction associated with regional ventricular wall abnormalities extending beyond the regions of coronary blood supply ensues.[2] The suspected prevalence of Kounis …

Initial Evaluation Of A Wellness Game, Bing Parkinson, Bruce St. Amour

Capital Division GME Virtual Research Day 2020

Physician wellness has recently been a topic of significant national interest.^1-8 The term “wellness” has many definitions, and was best defined by Around et al. ¹ as “one’s personal recipe for thriving and not just surviving.” Wellness refers to interconnected dimensions of physical, mental, and social well-being that extend beyond the absence of illness. Wellness has traditionally been measured in the negative sense by assessing rates of burnout, emotional exhaustion, and depersonalization. It is known that physician burnout is at its highest point during residency^{1, 4, 5} and burnout is linked to many negative outcomes including: substance abuse …

Internal Hernia As A Late Complication Of Roux-En-Y Gastric Bypass Procedure, Samantha Purton, Gabriel Meshekow, My Myers, Edgar Mercado, Allan Katz

West Florida Division GME Research Day 2020

As the prevalence of obesity continues to rise, so does the popularity of bariatric surgery. Previously the Roux-en-Y gastric bypass was the most common bariatric procedure, but now falls second to the gastric sleeve. It remains a relevant procedure, however, accounting for 17% of bariatric procedures in 2018. Due to its prevalence, it is important that the radiologist be familiar with the procedure and its complications such as leak, obstruction, stricture, or, as in this case, internal herniation through a mesenteric defect. Internal hernias are more commonly associated with the laparoscopic approach versus open. This is likely due to fewer …

Ada News - 06/01/2020, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Medical-Legal Collaboration And Community Partnerships: Prioritizing Prevention Of Human Trafficking In Federally Qualified Health Centers, Kimberly S.G. Chang Md, Mph, Hamida Yusufzai, Anna Marjavi

Georgia State University Law Review

Human trafficking (HT) is increasingly recognized as a public health issue, and its severe consequences affect some of society’s most vulnerable members. Prioritizing prevention is a critical component of a public health framework when addressing HT, and the health care delivery system plays a crucial role in operationalizing primary, secondary, and tertiary prevention interventions. As a significant part of the primary care system in the U.S., Federally Qualified Health Centers (FQHCs) are uniquely positioned to be the first point of contact with the health care system for people at risk for and affected by HT. FQHCs provide many preventive services, …

Understanding Risk And Prevention In Midwestern Antitrafficking Efforts: Service Providers' Perspectives, Hannah E. Britton Ph.D.

Georgia State University Law Review

Since the 2000 passage of both the Trafficking Victims Protection Act (TVPA) and the U.N.’s Palermo Protocols, human trafficking has gained a notable global presence as a human rights concern. Community organizations, nonprofits, scholars, policymakers, and service providers have developed programs to identify and address human trafficking. Despite these efforts, finding reliable methods to document and quantify the instances of human trafficking continues to challenge researchers. Moreover, many believe trafficking is a problem primarily located in urban areas or along national borders.

Drawing from seven years of interviews with service providers who work in this sector, combined with survey results …

Gender Integration In Social And Behavior Change: What Does It Take?, University Research Co., Breakthrough Research

Poverty, Gender, and Youth

This document pulls from a recent review of social and behavior change (SBC)-focused literature and highlights eight promising practices regarding how to integrate gender considerations in health and non-health SBC interventions. The practices are operationalized at different levels of the Socio-Ecological Model for Change and are mutually reinforcing. The purpose of this document is to share these promising practices with SBC partners to strengthen gender integration and mainstreaming efforts in SBC programming.

Behavioral Sentinel Surveillance Survey In Nigeria: Baseline Technical Report, Emily White Johansson, Paul Hutchinson, Elizabeth Omoluabi, Akanni Akinyemi, Andrea Smith, J. Clint Welty, Udochisom Anaba, Dominique Meekers, Alejandra Leyton, Dele Abegunde, Paul C. Hewett

Poverty, Gender, and Youth

This technical report presents results of the baseline Behavioral Sentinel Surveillance survey by Breakthrough RESEARCH in Nigeria in September and October 2019. From 2019 to 2021, baseline, midline, and endline surveys will assess the effectiveness of Breakthrough ACTION integrated social and behavior change activities for malaria, family planning, and maternal, newborn and child health plus nutrition in Kebbi and Sokoto in comparison to Breakthrough ACTION's exclusively malaria activities in Zamfara state. Malaria activities were initiated in Zamfara in October 2019. This technical report presents detailed baseline results, including comparisons of results for the Breakthrough ACTION integrated and malaria-exclusive program areas. …

Costs Of Maternity Leave To Support Breastfeeding; Brazil, Ghana And Mexico, Mireya Vilar-Compte, Graciela M. Teruel, Diana Flores-Peregrina, Grace J. Carroll, Gabriela S. Buccini, Rafael Perez-Escamilla

Department of Public Health Scholarship and Creative Works

Objective To develop a method to assess the cost of extending the duration of maternity leave for formally-employed women at the national level and apply it in Brazil, Ghana and Mexico. Methods We adapted a World Bank costing method into a five-step method to estimate the costs of extending the length of maternity leave mandates. Our method used the unit cost of maternity leave based on working women’s weekly wages; the number of additional weeks of maternity leave to be analysed for a given year; and the weighted population of women of reproductive and legal working age in a given …

The Impact Of A Single Session Of Mindfulness Meditation On The Attentional Blink In Non-Meditators, Arielle L. Klopsis

Dissertations, Theses, and Capstone Projects

Attentional resources are limited therefore a stimulus can go undetected if it closely follows another target by 200-500ms. This phenomenon is known as the attentional blink. Mindfulness meditation has been shown to be beneficial in target detection and in decreasing the attentional blink. Since there is no standard for the type of meditation or duration of practice that leads to attention benefits, this study compares the two most popular types of meditation in a group of non-meditators: focused attention and open monitoring meditation. This study utilized an attentional blink paradigm to measure if a single session of mindfulness meditation can …

Factors Predicting Sustainability: A Correlational Study Of One Multi-Site Program, Meredith L. King Jensen

Dissertations, Theses, and Capstone Projects

Healthcare organizations invest significant economic, physical, and human resources to implement changes and expect sustained benefits for their investments in the long term. Yet, few studies have examined long-term sustainability and factors contributingto sustainability. The primary aim of the study was to gain a better understanding of sustainability and five factors (champions, leadership support, policy, resources, and training and education) that might predict long-term sustainability within the context of one Safe Patient Handling and Mobility (SPHM) program implemented in a large, nationwide system more than 7 years ago. The secondary aim was to examine the number of nursing staff injuries, …

Creating Content For A Healthy New Life, Valeria C. Borja Lopez

Dissertations, Theses, and Capstone Projects

Creating Content for a Healthy New Life is a project consisting of the development of a web page to connect holistic practitioners to people. This page will also allow for the promotion and sale of Ayurvedic Skincare products and services. For the capstone project, I developed a business model for the enterprise. This model offers an educational component by educating our customers to understand the importance of using holistic approaches rather than traditional ones. For this, two videos were developed to educate customers about Ayurveda and the science behind the proposed products and services. I am an experienced Holistic Practitioner, …

Behavioral Outcomes In Children With Autism Spectrum Disorder And Cochlear Implants, Patricia K. Herz

Dissertations, Theses, and Capstone Projects

The purpose of this literature review was to establish what is currently known about behavioral outcomes of children with Autism Spectrum Disorder (ASD) and cochlear implants (CIs). Sixteen articles were included in this review. The areas investigated were behavioral changes postimplantation, as determined by subjective and objective measures, mode of communication used by children with ASD and CIs, and effects of additional comorbidities on these outcomes. Considerations for CI use for children with ASD include potential hypersensitivity to auditory stimuli, inability to complete performance measures, and markedly slower progress than their typically developing peers. Many of the studies included in …

Assistive Listening Devices: A Guide, Alexa Brody

Dissertations, Theses, and Capstone Projects

Objective: The purpose of this research was to develop a guide on assistive listening devices (ALDs) describing the various types of ALDs, the basic underlying concepts, their advantages and disadvantages, the instrumentation and its components, and the setup and procedures for specification/evaluation of ALDs in accordance with national standards or guidelines issued by professional organizations in our field. This guide is intended for audiologists, hearing scientists, and audiology and hearing science students.

Method: A thorough review of the previous ALD literature including national and international standards for set-up and installation, specification/evaluation and verification of ALDs; guidelines from professional audiology and …

Maximum Sound Output Levels Of Pediatric Marketed Headphones: The Development Of Healthy Listening Habits In Children, Adrienne L. Ammirati

Dissertations, Theses, and Capstone Projects

Background: In recent years there has been a growing concern regarding the etiology of pediatric hearing loss. Based on cross-sectional studies of data produced by the National Health and Nutrition Examination Surveys, the incidence of hearing loss in US adolescents (age 12-19 years) has increased from 14.9 to 19.5% from 1988-2006 (Shargorodsky, Curhan, & Eavey, 2010) (Brooks & Chan, 2017). Many individuals suspect the leading contributor of this to be frequent exposure to unsafe listening conditions (Muchnik, Amir, Shabtai, & Kaplan-Neeman, 2012) (Brookhouser, Wothington, & Kelley, 1992).

Presently there are no government issued regulations on the maximum sound output …

The Perception Of Prosody In English-Speaking Children With Cochlear Implants: A Systematic Review, Grace R. Smith

Dissertations, Theses, and Capstone Projects

Objective: The goal of this paper was to systematically review literature in order to investigate the perception of prosody in English-speaking children with cochlear implants.

Methods: A comprehensive search utilizing various peer-reviewed databases accessible through the City University of New York (CUNY) Graduate Center Library was conducted to identify relevant studies. Inclusion criteria included studies that examined prosody perception in pre-and post-lingually deafened children with cochlear implants. Children who utilized unilateral, bilateral, and bimodal configurations of cochlear implants were therefore included in this search.

Results: 9 studies met the inclusion criteria for this systematic review. The findings …

Primary Care Physician Perceptions Of Hearing Loss And Amplification: A Survey, Sophie Racine

Dissertations, Theses, and Capstone Projects

The goal of this survey is to determine primary care physicians’ (PCP) views regarding hearing loss and hearing amplification. A questionnaire was created, using TypeForm©. Factors interrogated in the survey included structural aspects of the health care delivery system, presence of stigma among providers regarding hearing amplification, PCPs’ knowledge of hearing loss, the utility of amplification, official recommendations on screening and amplification, costs of hearing aids and risks of untreated hearing loss, and practitioners’ viewpoints and practice behaviors surrounding hearing loss and amplification. The survey instrument is comprised of four domains: 1) demographics, 2) knowledge of hearing loss and amplification, …

A New Method In Subjective Tinnitus Management: The Use Of A Nutraceutical Formulation To Improve Patient Outcomes, Jade Faulkner

Dissertations, Theses, and Capstone Projects

Objective: This project aims to implement an evidence-based clinical practice guideline at the International Hearing Centre (IHC) in Lagos, Nigeria for future research and data collection of their subjective tinnitus management using a nutraceutical formulation called ‘NHANCED Hearing (NH). After learning the IHC had incomplete charting in regard to tinnitus questionnaires pre- and post-administration of the NH formula, this capstone project sought to apply evidence-based guidelines for proper diagnostic evaluations and charting to assist in future research of the NH formula.

Methodology: A review and synthesis of current clinical practice guidelines in the United States, Germany, the Netherlands, Sweden, Denmark, …

Application Of Multi-Omics Technologies To Decipher Rabies Pathogenesis, Peerut Chienwichai, Onrapak Reamtong

The Thai Journal of Veterinary Medicine

Rabies virus infection has affected human and animal health since ancient times and existing treatments are only partially effective. A thorough understanding of rabies virus pathogenesis is required to achieve improved treatment options and the eventual elimination ofthe disease. In recent years, multi-omics technology has emerged as a powerful tool for understanding viral pathogenesis. However, multi-omics data is lacking for the rabies virus. The aim of this review is to summarize our current understanding of rabiespathogenesis and its study using omics approaches. Several mechanisms have been proposed to contribute to rabies pathogenesis using the results of omics studies. Using data …

Production Of Recombinant Chimeric Swine Pkr-Apaf-1 Protein And Its Apoptotic Inductionon Marc-145 Cells, Phong Vu Anh Tuan Vo, Thanaporn Leksakchai, Roongtham Kedkovid, Achara Tawatsin, Athipoo Nuntaprasert

The Thai Journal of Veterinary Medicine

No abstract provided.

Survival Time And Factors Influencing Survival Time In Cats With Arterial Thromboembolism In Thailand, Sirilak Disatian Surachetpong, Selapoom Pairor, Thanika Atiptamvaree, Tanawan Mangklabruks

The Thai Journal of Veterinary Medicine

This study aimed to report the survival time and to determine factors influencing survival time in cats with arterial thromboembolism (ATE) in Thailand. The medical records of 89 ATE cats presenting from January 2016 to December 2018 at four referral centers in Thailand were reviewed. The median survival time of ATE cats was 31 days (interquartile range 3-59 days). Cats with an age of at least 5 years (7 days; 95% confidence interval (CI) 0-25.961) had a shorter survival time than those with an age <5 years old (136 days; 95% CI 0-643.216) (p=0.021). Persian cats (450 days; 95% CI 0-37.552) had a longer survival time than other breed cats (15 days; 95% CI 0.799-7.201) (p=0.044). The multivariable Cox-regression analysis showed that a higher concentration of alanine aminotransferase (ALT) (p=0.002; Hazard ratios (HR)=1.002), circulating glucose (p=0.031; HR=1.005), and creatinine (p=0.011; HR=1.207) were associated with an increased risk of death. In conclusion, the survival time of cats with ATE in Thailand is reported. Age and breed influence the survival time of cats with ATE. The concentration of ALT, circulating glucose and creatinine is associated with an increased risk of death.

Effectiveness Of Embalming Solutions With Partial Replacement Of Formaldehyde And Phenol With Ethanol And Sodium Chloride On Mice Over 18 Months, Kriengyot Sajjacharoenpong, Pawana Chuesiri

The Thai Journal of Veterinary Medicine

Animal preservation for anatomy teaching has been required to replace formaldehyde and phenolwhich represent a health hazard to humans. A comparative study of embalming solutions with partial replacement of formaldehyde and phenol with sodium chloride and ethanol was evaluated in mouse cadavers over an 18-month period. Twelve adult mouse carcasses were divided into six groups of two mice each. After openingthe mouse’s skin,the internal organswere removed and preserved with the remaining cadavers by freezing (Group I, control group) or in the respective embalming solution (Groups II to VI) and examined after 3, 6, 12 and 18 months. For the embalming …

Morphological Study Of The Lingual Papillae Of Jentink’S Flying Squirrel(Hylopetes Platyurus), Hevi Wihadmadyatami, Golda Rani Saragih, Geraldus Gunawan, Made Bagus Auriva Mataram, Ulayatul Kustiati, Dwi Liliek Kusindarta

The Thai Journal of Veterinary Medicine

This study describes the anatomy and histology of the tongue in the Jentink’s flying squirrel (Hylopetesplatyurus), a rodent native to Indonesia (Borneo and Sumatra). We examined the characteristics of the tongue using scanning electron microscopy (SEM) and light microscopy (LM). Macroscopic observations revealed three distinct regions: the apex, corpus (body) and radix (root). The dorsal surface of the apex was characterized by a median groove and lacked the lingual prominence that is common in many rodents. SEM and LM revealed the distribution of papillae over the dorsal surface of the tongue. The papillae could be categorized as mechanical papillae (filiform, …

Grains, Grasses, And Tubers: Staple Carbohydrates In The Diets Of Middle School Children Of Southern Zambia And Ethiopia, Brianna Juma

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Survey staple carbohydrate availability in local markets, complete anthropometric assessment, and interview primary school children about carbohydrate consumption in Southern Zambia and Ethiopia

Methods: Market inventories, anthropometric assessments, and interviews of 6th and 7th grade students

Results: Ethiopians have a greater diversity of available carbohydrates, have better overall anthropometric values compared to Zambian children, and consume more nutritious and varied carbohydrate types.

Conclusions: Diversity in carbohydrate availability and consumption, as well as more nutritious options, are associated with healthier growth rates among primary school children in Southern regions of Zambia and Ethiopia.

Wolff-Parkinson-White Syndrome: De Novo Variants And Evidence For Mutational Burden In Genes Associated With Atrial Fibrillation, Zeynep H Coban-Akdemir, Wu-Lin Charng, Mahshid Azamian, Ingrid S Paine, Jaya Punetha, Christopher M Grochowski, Tomasz Gambin, Santiago O Valdes, Bryan Cannon, Gladys Zapata, Patricia P Hernandez, Shalini Jhangiani, Harsha Doddapaneni, Jianhong Hu, Fatima Boricha, Donna M Muzny, Eric Boerwinkle, Yaping Yang, Richard A Gibbs, Jennifer E Posey, Xander H T Wehrens, John W Belmont, Jeffrey J Kim, Christina Y Miyake, James R Lupski, Seema R Lalani

Faculty, Staff and Student Publications

BACKGROUND: Wolff-Parkinson-White (WPW) syndrome is a relatively common arrhythmia affecting ~1-3/1,000 individuals. Mutations in PRKAG2 have been described in rare patients in association with cardiomyopathy. However, the genetic basis of WPW in individuals with a structurally normal heart remains poorly understood. Sudden death due to atrial fibrillation (AF) can also occur in these individuals. Several studies have indicated that despite ablation of an accessory pathway, the risk of AF remains high in patients compared to general population.

METHODS: We applied exome sequencing in 305 subjects, including 65 trios, 80 singletons, and 6 multiple affected families. We used de novo analysis, …

Improving Perioperative Communication Through The Use Of A Nurse Navigator: An Integrative Review, Elizabeth Irene Christman

Doctoral Dissertations and Projects

Patient-centered communication practices are critical for ensuring that patients have optimal care experiences and clinical outcomes. Unfortunately, today’s health care environment often presents numerous barriers to consistent and clear information exchange. These barriers are magnified in dynamic and fast-paced care environments such as the perioperative setting, where numerous interactions and communication exchanges must occur. The purpose of this integrative review is to examine the value of the nurse navigator role within the perioperative setting and evaluate whether it can improve patient and family satisfaction with communication and the care experience. The review includes the identification and appraisal of relevant literature …

Smart Environments For Assisted Living: A Multidisciplinary Collaboration In Engineering And Architecture Education, Adriana Rios-Santiago, Anabel Pineda-Briseno, Jesus A. Gonzalez-Rodriguez, Uriel Saul Huerta

Manufacturing & Industrial Engineering Faculty Publications

This paper presents a description of a collaborative project based on the integration of technology development in the built environment for assisted living. The multidisciplinary collaboration is developed as a cooperative commitment to provide support for cross-border, collective projects. It was initiated as a project-based learning setting between undergraduate engineering students, and four years later the program shifted to include undergraduate architecture students and engineering master’s students. The learning experience opens the gate to a completely new collaborative setting, yet to be established, independent from its predecessor setting of project-based learning, focusing now towards an interdisciplinarity setting in cross-border collaboration. …