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Articles 31 - 60 of 21498
Full-Text Articles in Medicine and Health Sciences
A Rare Presentation Of Myelopathy In Novice Surfers: A Casereport And Literature Reviewarticle, Ming-Hsuan Huang, Shu-Fen Sun, Min-Hui Li, Ping-Hong Lai
A Rare Presentation Of Myelopathy In Novice Surfers: A Casereport And Literature Reviewarticle, Ming-Hsuan Huang, Shu-Fen Sun, Min-Hui Li, Ping-Hong Lai
Rehabilitation Practice and Science
Introduction: Surfer's myelopathy is a nontraumatic, ischemic spinal cord injury that predominantly affects the lower thoracic cord. Owing to its clinical rarity, its pathophysiology and treatment protocol remain controversial. Frequently discussed hypotheses regarding its cause include ischemic change due to trunk hyperextension and the Valsalva maneuver, leading to back pain, weakness in the lower extremities, and bowel and bladder dysfunction. The prognosis varies widely, ranging from full recovery to paraplegia. casereport: We report the case of a 22-year-old female patient experiencing progressive loss of strength in the lower extremities and soreness in her lower back while surfing for the first …
Plantar Fasciopathy At Unusual Location: A Report Of Two Cases, Chia-Hua Lee, Feng-Cheng Tang, Yao-Jen Chen, Long-Wei Dai, Su-Ju Tsai, Chi-Chung Ho
Plantar Fasciopathy At Unusual Location: A Report Of Two Cases, Chia-Hua Lee, Feng-Cheng Tang, Yao-Jen Chen, Long-Wei Dai, Su-Ju Tsai, Chi-Chung Ho
Rehabilitation Practice and Science
Plantar fasciopathy is a common problem in the general population involving the proximal area of the central cord of the plantar aponeurosis. Few studies have discussed plantar fasciopathy distal to the calcaneus. In article reviewarticles, plantar fasciopathy distal to the calcaneus occurred in only 12% of the cases. In the casereport, including two cases in which fasciopathy were involved in the central part of the plantar fascia, the incidence was obviously less than that mentioned above. These two cases were atypical diseases of plantar fasciopathy over the plantar arch. They both received one to several sessions of prolotherapy, but no …
Coinstantaneous Brachial Plexus Injuries In A 55-Year-Old Man With Traumatic Spinal Cord Injury: A Casereport And Literature Reviewarticle, Hong-Yi Lin, Jia-Yin Guo, Su-Ju Tsai
Coinstantaneous Brachial Plexus Injuries In A 55-Year-Old Man With Traumatic Spinal Cord Injury: A Casereport And Literature Reviewarticle, Hong-Yi Lin, Jia-Yin Guo, Su-Ju Tsai
Rehabilitation Practice and Science
脊髓損傷合併臂神經叢損傷臨床上少見且不易診斷與處置。過去研究的報告發生率約為0.6%到1.8%。在脊髓損傷的病人處置時,通常優先處理危及生命的傷害,且臂神經叢損傷的臨床表現也可能歸因於脊髓損傷而被忽略。本文報告一名55歲因車禍意外導致第四節脊髓損傷的男性病人,根據病人的身體檢查、神經學檢查發現右上肢深肌腱反射無反應,以及明顯不對稱的右上肢與左上肢肌力,經過神經傳導檢查及肌電圖檢查,確定該名病人為脊髓損傷合併臂神經叢損傷。同時罹患脊髓損傷及臂神經叢損傷的病人數量可能被低估,治療計畫及復健也更為複雜,早期診斷與適當治療是此類病人上肢功能恢復的重要關鍵。除了詳細探查脊髓損傷病人的臨床症狀、身體檢查、神經學檢查之外,電學診斷對於合併臂神經叢損傷的確診最有效益。
School Absenteeism Among Adolescent Girls Due To Menstruation Related Issues – A Cross-Sectional School Based Study, Parul Malik
School Absenteeism Among Adolescent Girls Due To Menstruation Related Issues – A Cross-Sectional School Based Study, Parul Malik
Manipal Journal of Medical Sciences
Introduction: Problems related to menstruation are one of the most common issues faced by adolescent girls all over India. To improve academic performances among adolescent girls and to reduce menstruation-related school absenteeism, it is important to understand and address the factors affecting school absenteeism during menstruation. Methods: This was a school-based survey conducted for six months from January to June 2019 in the Udupi district of Karnataka State. A semi-structured questionnaire with four domains, namely - sociodemographic variables, awareness on menstruation, menstrual products used and school absenteeism due to menstruation was administered. 1546 responses were received. Results: The participants of …
Sources Of Nutrition Information In Recreational Ultra-Marathon Runners: A Mixed Methods Analysis, Sara E. Mahoney, Thomas R. Wójcicki, Andrew J. Carnes
Sources Of Nutrition Information In Recreational Ultra-Marathon Runners: A Mixed Methods Analysis, Sara E. Mahoney, Thomas R. Wójcicki, Andrew J. Carnes
Journal of Human Performance in Extreme Environments
Ultra-marathon events (i.e., .42.2-km) continue to grow in popularity; however, little is known regarding the sources of nutrition information which inform their beliefs and habits. The objective of this study was to characterize the acquisition of sport-specific nutrition information among ultra-endurance athletes using a mixed methods design. Qualitative data were collected through focus groups and analyzed using thematic analysis. Three primary higher order themes were identified: Optimal Diet for Ultra-Endurance Athletes, Common Sources of Information, and Barriers to Scientific Information. Then, a self-report inventory (Sources of Nutrition Information-SONI questionnaire) was developed to assess common sources of nutrition information and characterize …
Perspectives On Finances And Mental Health Status Among Low-Income Los Angeles Latinas, Luisa R. Blanco, Jessica A. Baker, Julie A. Friedman, Karen T. Singh, Arleen F. Brown, Sierra D. Moon, Savanna L. Carson, Audree Hsu, Janet Pregler
Perspectives On Finances And Mental Health Status Among Low-Income Los Angeles Latinas, Luisa R. Blanco, Jessica A. Baker, Julie A. Friedman, Karen T. Singh, Arleen F. Brown, Sierra D. Moon, Savanna L. Carson, Audree Hsu, Janet Pregler
Journal of Financial Therapy
Abstract
Research has established a link between financial challenges and mental health outcomes. Understanding this linkage among low-income Latinas who face unique experiences and challenges in relation to managing their household finances is important. This study utilized a community-based participatory qualitative research method to explore perspectives on financial and mental health among Latinas residing in Los Angeles County. The implications of this study are applicable when conducting a culturally responsive financial therapy program. Three focus groups were conducted with mainly immigrant, Spanish-speaking, low-income Latinas (n = 37). The study found that though participants face financial stressors tied to managing finances, …
Right To Play's Intervention To Reduce Peer Violence Among Children In Public Schools In Pakistan: A Cluster-Randomized Controlled Trial, Rozina Karmaliani, Judith Mcfarlane, Hussain Maqbool Ahmed Khuwaja, Yasmeen Hassan Somani, Shireen Shehzad, Tazeen Saeed Ali, Nargis Asad, Esnat D. Chirwa, Rachel Jewkes
Right To Play's Intervention To Reduce Peer Violence Among Children In Public Schools In Pakistan: A Cluster-Randomized Controlled Trial, Rozina Karmaliani, Judith Mcfarlane, Hussain Maqbool Ahmed Khuwaja, Yasmeen Hassan Somani, Shireen Shehzad, Tazeen Saeed Ali, Nargis Asad, Esnat D. Chirwa, Rachel Jewkes
School of Nursing & Midwifery
Background: Peer violence is common globally, but a little researched topic in low-and middle-income countries. This study presents the evaluation of a two-year randomized controlled trial of a structured play-based life-skills intervention implemented in schools in Hyderabad, Pakistan.
Objective: To determine the impact of the intervention on school-based peer violence (victimization and perpetration) and depression among school children.
Methods: 40 single-sex public schools were randomized into two study arms (20 per arm 10 of each sex). A total of 1752 grade 6 students (929 from intervention and 823 from control schools) were enrolled in the trial. The two-year intervention was …
Digital Revolution During Covid-19 Era, Monalisa Biswas
Digital Revolution During Covid-19 Era, Monalisa Biswas
Manipal Journal of Medical Sciences
Triaging is of utmost importance in any pandemic and is essential in the present COVID-19 times when we are witnessing an enormous number of our population being affected by the novel coronavirus. Further, it is important to acknowledge the varied spectrum of manifestations among our patients with each patient needing a tailored protocol and facilitating in gaining an understanding of the epidemiology and disease pathophysiology. The rapid spread of COVID-19 and shortage of health care personnel in a developing country like India needs immediate and effective health technology to triage COVID suspects thereby reducing doctor – suspects’ contact and monitor …
To Mask Or Not To Mask During An Infectious Outbreak - Perspective, Thanigasalam Thevi
To Mask Or Not To Mask During An Infectious Outbreak - Perspective, Thanigasalam Thevi
Manipal Journal of Medical Sciences
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“Sampark Snehi”: Telemedicine Consultation In Covid-19 Times At A Private Medical College Hospital – Digitalised Solution, Vijetha Belle
“Sampark Snehi”: Telemedicine Consultation In Covid-19 Times At A Private Medical College Hospital – Digitalised Solution, Vijetha Belle
Manipal Journal of Medical Sciences
Every life is precious and every patient matters: In a country with 5.5 government beds for 10,000 population, even a marginal increase in hospitalization increases the pressure on the system exponentially. The spread of COVID-19 has kindled the need for transformation from traditional face-to-face doctorpatient communication to a telehealth platform. During the lockdown, reduced access to both outpatient and hospitalization services is proving to be fatal for countless non-covid patients. Taking lead in addressing the health care needs and demands of the society we cater to, E-consultation which has been initiated by most of the medical colleges providing tertiary care, …
Facts About Asthma Insights And Treatment Regimen: A Hospital Based Survey, Krishnananda Prabhu
Facts About Asthma Insights And Treatment Regimen: A Hospital Based Survey, Krishnananda Prabhu
Manipal Journal of Medical Sciences
Background: Bronchial asthma is the most prevalent chronic lung diseases. Morbidity and mortality associated with asthma has also continued to increase despite advances in treatment and management. Asthma vary from region to region due to the variability of extrinsic allergens that play a major role in sensitizing susceptible individuals. As an allergenic disease, environmental factors are of more importance than genetic factors in the etiology of bronchial asthma. Patient awareness and treatment regimen have a strong influence on outcome and stabilization of asthma. Objective: This survey was to evaluate the knowledge about triggering factors and treatment regimen among asthma patients. …
Managing Excess Inventory Of Stores In A Hospital, Naveen Kumar
Managing Excess Inventory Of Stores In A Hospital, Naveen Kumar
Manipal Journal of Medical Sciences
Inventory costs in hospitals vary from 30 to 40 percent of the hospital operating costs per year. Inventories are materials and supplies that a hospital carries for patient care. Often, they are a substantial part of the total assets of a hospital. Quick liquidation is imperative in real-time scenarios like value recovery, getting rid of excess material or bringing down logistics cost. Due to poor handling of finances by purchase managers without prior retail management education – the ordering systems, vendor payments management of the hospitals will not be ideal, which will affect vendor relations. In this scenario, this study …
Let Nutrition Be Your Vaccine Amid Covid-19- A Narrative Review, Vidya Rajesh
Let Nutrition Be Your Vaccine Amid Covid-19- A Narrative Review, Vidya Rajesh
Manipal Journal of Medical Sciences
There has been a growing body of evidence highlighting the radical effect of nutrition on the immune system and disease susceptibility. The current COVID-19 crisis awakens an urgent calling for optimum nutrition which boosts immunity and prevents diseases, just like a vaccine. Though there have been several national guidelines regarding diet during COVID-19, there has been sparse research and literature available in this field. This review aims to summarise the existing evidence on various aspects of nutrition and immunity pertaining to the COVID-19 crisis. Literature and search strategy included PubMed and Google Scholar for articles on various aspects of nutrition …
Metastatic Genital Crohn’S Disease: Visceral Devil In The Details- A Case Report, Soumya Kanti Datta
Metastatic Genital Crohn’S Disease: Visceral Devil In The Details- A Case Report, Soumya Kanti Datta
Manipal Journal of Medical Sciences
Crohn’s disease (CD) is a chronic inflammatory bowel disease (IBD) commonly associated with extraintestinal manifestations such as arthritis, uveitis, deep venous thrombosis and erythema nodosum. Asymmetrical labial swelling and edema are the most common presentations of genital CD in females. Vulval CD can appear before or after gastrointestinal (GI) CD or it may occur simultaneously with an independent course of disease and response to treatment. Here we discuss an atypical case of metastatic vulvar CD presenting as perineal and perianal ulcers and erosions successfully treated with oral doxycycline and topical corticosteroids hence making it an exciting new treatment avenue to …
Role Of Statins In Covid-19, Bharti Chogtu
Post-Partum Haemorrhage - The Ultimate Challenge To Emergency Medicine, Akshata Ammembal
Post-Partum Haemorrhage - The Ultimate Challenge To Emergency Medicine, Akshata Ammembal
Manipal Journal of Medical Sciences
Post-partum haemorrhage (PPH) is a leading cause of maternal mortality globally. This report elaborates the diagnosis and treatment of a 31-year-old woman with PPH, treated in our tertiary centre. On presentation, she showed all signs of hypovolemic shock and disseminated intravascular coagulation (DIC). Persistent fresh vaginal bleeding led to the decision to perform an emergency hysterectomy. She required massive transfusion but consequently developed transfusion-associated lung injury (TRALI), for which she was effectively treated. She made a full recovery leading to discharge 12 days after admission. This article stresses the importance of the multi-disciplinary approach and rapid, coordinated management of emergency …
Cold Storage Work And Cold Protective Gloves – A Review, Daena Charles
Cold Storage Work And Cold Protective Gloves – A Review, Daena Charles
Theses
The rise of e-commerce and the increasing demand for online grocery shopping and delivery has prompted the growth of warehouse workers subjected to cold temperature working conditions. To ensure food safety and the preservation of inventory, majority of these e-grocery warehouses are cold storage with temperatures from 10°C to -23°C. Exposure to such cold working environments can have effects on the workers comfort, performance and health. As the demand for workers in cold temperature environments increases, it is important to understand how this environment affects the workers and the challenges it may present.
This review evaluates how working in cold …
Research News. Publications, 2020. Volume 4, Soumyajit Majumdar
Research News. Publications, 2020. Volume 4, Soumyajit Majumdar
Publications (2015-)
Publications that appeared during the period October 1 through December 31, 2020
Therapeutics Development For Pseudoxanthoma Elasticum And Related Ectopic Mineralization Disorders: Update 2020., Hongbin Luo, Qiaoli Li, Yi Cao, Jouni Uitto
Therapeutics Development For Pseudoxanthoma Elasticum And Related Ectopic Mineralization Disorders: Update 2020., Hongbin Luo, Qiaoli Li, Yi Cao, Jouni Uitto
Department of Dermatology and Cutaneous Biology Faculty Papers
Pseudoxanthoma elasticum (PXE), the prototype of heritable ectopic mineralization disorders, manifests with deposition of calcium hydroxyapatite crystals in the skin, eyes and arterial blood vessels. This autosomal recessive disorder, due to mutations in ABCC6, is usually diagnosed around the second decade of life. In the spectrum of heritable ectopic mineralization disorders are also generalized arterial calcification of infancy (GACI), with extremely severe arterial calcification diagnosed by prenatal ultrasound or perinatally, and arterial calcification due to CD73 deficiency (ACDC) manifesting with arterial and juxta-articular mineralization in the elderly; the latter disorders are caused by mutations in ENPP1 and NT5E, respectively. The …
The 21st Century Global Digital Economies Revolution And The Aftermath Of Covid-19 Pandemic: Some Anticipated Implication Changes For Developing Nations, Agyei Fosu
ASEAN Journal of Community Engagement
The 21st century digital global economies era changed developmental approaches drastically to a point where most researchers, policy makers, and developers have asserted that to achieve economic development for developing nations; it is paramount for Information and Communications Technologies (ICTs) investments in all sectors contributing to their economy. The current COVID-19 pandemic and the various measures taken by governments such as lockdown, curfew, companies asking employees to work from home, and the use of e-learning by schools to curb the disease brings into perspective the assertion raised by various scholars about the need for developing nations to invest in …
Tragedy Of The Energy Commons: How Government Regulation Can Help Mitigate The Environmental And Public Health Consequences Of Cryptocurrency Mining, Jeff Thomson
Seattle Journal of Technology, Environmental & Innovation Law
The use of cryptocurrencies in daily life has continued to rise over the last decade and shows no signs of slowing down. Although cryptocurrencies, such as Bitcoin, provide numerous tangible benefits to society, the process of mining these cryptocurrencies is extremely energy intensive. Accordingly, a tragedy of the energy commons has resulted whereby the monetary incentive to mine cryptocurrencies has distorted our collective ability to care for our shared energy resources. The current system allows for industrious individuals to set up cryptocurrency mines in regions that have access to plentiful and cheap energy sources, utilize this energy to power their …
Excisional Treatment Comparison For In Situ Endocervical Adenocarcinoma (Excise): A Phase 2 Pilot Randomized Controlled Trial To Compare Histopathological Margin Status, Specimen Size And Fragmentation After Loop Electrosurgical Excision Procedure And Cold Knife Cone Biopsy, Paul A. Cohen, Yee Leung, Lyndal Anderson, Rachael Van Der Griend, Paola Chivers, Sanela Bilic, Sophie Bittinger, Alison Brand, Max K. Bulsara, Jim Codde, Lois Eva, Louise Farrell, Dianne Harker, Unine Herbst, Stephanie Jeffares, Diane Loh, Orla Mcnally, Ganendra Raj Mohan, Tarryn Nicholson, Aime Powell, Stuart G. Salfinger, Bryony Simcock, Colin Stewart, Julie Silvers, Martin R. Stockler, Peter Sykes, Pennie Stoyles, Adeline Tan, Ai Ling Tan, C. David H. Wrede
Excisional Treatment Comparison For In Situ Endocervical Adenocarcinoma (Excise): A Phase 2 Pilot Randomized Controlled Trial To Compare Histopathological Margin Status, Specimen Size And Fragmentation After Loop Electrosurgical Excision Procedure And Cold Knife Cone Biopsy, Paul A. Cohen, Yee Leung, Lyndal Anderson, Rachael Van Der Griend, Paola Chivers, Sanela Bilic, Sophie Bittinger, Alison Brand, Max K. Bulsara, Jim Codde, Lois Eva, Louise Farrell, Dianne Harker, Unine Herbst, Stephanie Jeffares, Diane Loh, Orla Mcnally, Ganendra Raj Mohan, Tarryn Nicholson, Aime Powell, Stuart G. Salfinger, Bryony Simcock, Colin Stewart, Julie Silvers, Martin R. Stockler, Peter Sykes, Pennie Stoyles, Adeline Tan, Ai Ling Tan, C. David H. Wrede
Research outputs 2014 to 2021
Objective:
Adenocarcinoma in situ (AIS) of the cervix is a precursor to cervical adenocarcinoma. When AIS is detected by cervical screening an excision biopsy is mandatory to exclude invasion. We aimed to compare margins status, specimen size and fragmentation after loop electrosurgical excision procedure (LEEP) and ‘cold knife cone biopsy’ (CKC).
Methods:
The EXCISE Trial was an investigator-initiated, multicenter, open-label, parallel-group, phase 2, randomized study. Patients were enrolled at seven hospitals in Australia and New Zealand. We randomly assigned women aged ≥ 18 to ≤ 45 years with screen detected AIS to LEEP or CKC. Co-primary endpoints were margin status, …
Inhibitory And Anti-Biofilm Effects Of Orthoshipon Aristatus Against Candida Albicans, Ratika Rahmasari, Ananda Hanny Chairunissa, Marina Ika Irianti, Roshamur Cahyan Forestrania, Ayun Erwina Arifianti, Herman Suryadi, Juliann Nzembi Makau, Ibrahim Jantan, Berna Elya
Inhibitory And Anti-Biofilm Effects Of Orthoshipon Aristatus Against Candida Albicans, Ratika Rahmasari, Ananda Hanny Chairunissa, Marina Ika Irianti, Roshamur Cahyan Forestrania, Ayun Erwina Arifianti, Herman Suryadi, Juliann Nzembi Makau, Ibrahim Jantan, Berna Elya
Pharmaceutical Sciences and Research
There are increasing number of reports on Candida albicans developing resistance to available anti-fungal drugs. Thus, there is an urgent need to discover new agents for treatment of candidiasis. The alcoholic extracts of Orthoshipon aristatus have been shown to exhibit antifungal activity against C. albicans by using the agar diffusion and broth microdilution methods. However, the underlying mechanisms of anti-C. albicans effect of O. aristatus have not been well understood. This study was aimed to evaluate the cytotoxic and anti-biofilm effects of the n-hexane and ethanol extracts of purple and white varieties of O. aristatus leaves …
Removal Of Mimosine From Leucaena Leucocephala (Lam.) De Wit Seeds To Increase Their Benefits As Nutraceuticals, Sri Wardatun, Yahdiana Harahap, Abdul Mun'im, Fadlina Chany Saputri Dr., Noorwati Sutandyo
Removal Of Mimosine From Leucaena Leucocephala (Lam.) De Wit Seeds To Increase Their Benefits As Nutraceuticals, Sri Wardatun, Yahdiana Harahap, Abdul Mun'im, Fadlina Chany Saputri Dr., Noorwati Sutandyo
Pharmaceutical Sciences and Research
The Leucaena leucocephala (Lam.) de Wit tree contains pharmacologically active compounds and can easily be found in abundant quantities. The utilization of this tree as a source of nutraceuticals would increase its value. The extraction yields show the number of compounds that have been extracted by solvent. However, Leucaena leucocephala (Lam.) de Wit seeds also contain mimosine, which can cause hair loss. The present study investigated the process of removing mimosine from the seeds. Three treatments were applied to these seeds: treatment without soaking, soaking with distilled water for 24 hours, and splitting the seeds in half and then soaking …
Low Serum Irisin As A Risk Factor Of Sarcopenia In Elderly, I Gust Putu Suka Aryana, I.B. Putrawan, Ni Ketut Rai Purnami, R.A. Tuty Kuswardhani, I Nyoman Astika, Ketut Suastika, I Putu Gede Adiatmika, I Made Jawi, I Nyoman Wande
Low Serum Irisin As A Risk Factor Of Sarcopenia In Elderly, I Gust Putu Suka Aryana, I.B. Putrawan, Ni Ketut Rai Purnami, R.A. Tuty Kuswardhani, I Nyoman Astika, Ketut Suastika, I Putu Gede Adiatmika, I Made Jawi, I Nyoman Wande
Jurnal Penyakit Dalam Indonesia
Introduction. Sarcopenia is a condition characterized by a decrease in muscle mass accompanied by a decrease in strength and/or function. Sarcopenia is closely related to the aging process, but the mechanism of its occurrence is still not fully understood. Skeletal muscle is the largest organ in the human body, so the myokine produced through muscle contraction opens a new paradigm regarding the central role of muscles in regulating metabolism and other organ functions. One of the myokines that are currently found to affect physical activity is Irisin. This study aims to determine the role of low Irisin levels in serum …
Correlation Of The Quality Of Antibiotic Usage By Utilising Gyssens Flow And The Success Of Treatment In Negative Gram Mdr Sepsis In Tertiary Hospital, Soroy Lardo, Lie Khie Chen, Widayat Djoko Santoso, Cleopas Martin Rumende
Correlation Of The Quality Of Antibiotic Usage By Utilising Gyssens Flow And The Success Of Treatment In Negative Gram Mdr Sepsis In Tertiary Hospital, Soroy Lardo, Lie Khie Chen, Widayat Djoko Santoso, Cleopas Martin Rumende
Jurnal Penyakit Dalam Indonesia
Introduction. Multi Drug Resistance (MDR) antibiotics have become a global health threat to the community. The use of appropriate antibiotics makes preventive and curative measures very important for the success of overcoming MDR and intervening the complexity of resistance, at least slowing the rate of occurrence of MDR. This study aimed to identify the difference in the quality of antibiotic use quality of use using gyssens flowchart and the success in sepsis patients’ treatment due to gram-negative MDR bacteria with non-MDR bacterial infections in tertiary hospitals. Methods. A retrospective cohort study was conducted using secondary data from patient with age …
The Selection Of Oral Antidiabetic Drugs In Type 2 Diabetes Mellitus Patients With High Risk For Cardiovascular Events, Derlin J. Leander, Dicky L. Tahapary
The Selection Of Oral Antidiabetic Drugs In Type 2 Diabetes Mellitus Patients With High Risk For Cardiovascular Events, Derlin J. Leander, Dicky L. Tahapary
Jurnal Penyakit Dalam Indonesia
Type 2 diabetes mellitus (DMT2) patients are associated with an increased risk of cardiovascular events. Prior to the era of cardio-vascular trial outcome (CVOT) evidence on the efficacy of old oral diabetes (OAD) drugs such as metformin, sulfonylurea, thiazolidindion, glinid, and alpha glucosidase inhibitors in reducing the risk of cardiovascular events was very limited. Since 2008, all OADs must have CVOT data. DPP-4 inhibitors are neutral against the risk of cardiovascular events while SGLT-2 inhibitors are reported to significantly reduce the risk of cardiovascular events. This finding even helped to change the DMT2 management guidelines issued by American Diabetes Association …
Preconceptional Lipid-Based Nutrient Supplementation In 2 Low-Resource Countries Results In Distinctly Different Igf-1/Mtor Placental Responses, Marisol Castillo-Castrejon, Ivana V. Yang, Elizabeth J. Davidson, Sarah J. Borengasser, Purevsuren Jambal, Jamie Westcott, Jennifer F. Kemp, Ana Garces, Sumera Aziz Ali, Sarah Saleem
Preconceptional Lipid-Based Nutrient Supplementation In 2 Low-Resource Countries Results In Distinctly Different Igf-1/Mtor Placental Responses, Marisol Castillo-Castrejon, Ivana V. Yang, Elizabeth J. Davidson, Sarah J. Borengasser, Purevsuren Jambal, Jamie Westcott, Jennifer F. Kemp, Ana Garces, Sumera Aziz Ali, Sarah Saleem
Community Health Sciences
Background: Preconceptional maternal small-quantity lipid-based nutrient supplementation (SQLNS) improved intrauterine linear growth in low-resource countries as demonstrated by the Women First Preconception Maternal Nutrition Trial (WF). Fetal growth is dependent on nutrient availability and regulated by insulin-like growth factor 1 (IGF-1) through changes in placental transfer capacity, mediated by the mechanistic target of rapamycin (mTOR) pathway.
Objectives: Our objective was to evaluate the role of placental mTOR and IGF-1 signaling on fetal growth in women from 2 low-resource countries with high rates of stunting after they received preconceptional SQLNS.
Methods: We studied 48 women from preconception through delivery who were …
The Impact Of “Code Stemi” Program Implementation On Door To Balloon Time And Major Adverse Cardiac Events Of Patients With St Elevation Myocardial Infarction, Prijander L B Funay, Ika Prasetya Wijaya, Eka Ginanjar, Hamzah Shatri
The Impact Of “Code Stemi” Program Implementation On Door To Balloon Time And Major Adverse Cardiac Events Of Patients With St Elevation Myocardial Infarction, Prijander L B Funay, Ika Prasetya Wijaya, Eka Ginanjar, Hamzah Shatri
Jurnal Penyakit Dalam Indonesia
Introduction. Delay in the management of ST Elevation Myocardial Infarction (STEMI) patients is a cause of high mortality and the incidence of major adverse cardiac events (MACE). Efforts that can be made in health facilities with primary percutaneous coronary intervention (PCI) capability are achieving timely reperfusion of STEMI patients. Various strategies were carried out to achieve timely reperfusion including implementation the CODE STEMI program. This study aimed to determine the effect of the implementation of the CODE STEMI program on Door to Balloon Time (D2BT) and MACE of STEMI patients undergoing primary PCI. Methods. This was a retrospective cohort study …
Hospitalized Adult Patient Characteristics Associated With Participation In A Volunteer-Assisted Mobility Program: A Feasibility Study, Gordana Dermody, Tamara Odom-Maryon, Jennifer Zimmerman, Courtney Glass
Hospitalized Adult Patient Characteristics Associated With Participation In A Volunteer-Assisted Mobility Program: A Feasibility Study, Gordana Dermody, Tamara Odom-Maryon, Jennifer Zimmerman, Courtney Glass
Research outputs 2014 to 2021
BACKGROUND:
Physical inactivity during hospitalization commonly results in functional decline. Structured multidisciplinary programs/approaches may be useful to promote mobility in hospitalized adults.
PURPOSE:
The purpose was to determine whether a volunteer-assisted mobility program was feasible to improve the ambulation of hospitalized patients, and examine the characteristics of patients associated with willingness to participate in the program.
METHODS:
A prospective descriptive correlation study was conducted in 2 acute care units. A volunteer-staffed program was implemented with the aim of improving the ambulation of hospitalized patients.
RESULTS:
Hospitalized patients (N = 490) were approached, with 39.2% (n = 192) agreeing to ambulate …