Medicine and Health Sciences Commons^™

Managing Excess Inventory Of Stores In A Hospital, Naveen Kumar

Manipal Journal of Medical Sciences

Inventory costs in hospitals vary from 30 to 40 percent of the hospital operating costs per year. Inventories are materials and supplies that a hospital carries for patient care. Often, they are a substantial part of the total assets of a hospital. Quick liquidation is imperative in real-time scenarios like value recovery, getting rid of excess material or bringing down logistics cost. Due to poor handling of finances by purchase managers without prior retail management education – the ordering systems, vendor payments management of the hospitals will not be ideal, which will affect vendor relations. In this scenario, this study …

Role Of Statins In Covid-19, Bharti Chogtu

Manipal Journal of Medical Sciences

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School Absenteeism Among Adolescent Girls Due To Menstruation Related Issues – A Cross-Sectional School Based Study, Parul Malik

Manipal Journal of Medical Sciences

Introduction: Problems related to menstruation are one of the most common issues faced by adolescent girls all over India. To improve academic performances among adolescent girls and to reduce menstruation-related school absenteeism, it is important to understand and address the factors affecting school absenteeism during menstruation. Methods: This was a school-based survey conducted for six months from January to June 2019 in the Udupi district of Karnataka State. A semi-structured questionnaire with four domains, namely - sociodemographic variables, awareness on menstruation, menstrual products used and school absenteeism due to menstruation was administered. 1546 responses were received. Results: The participants of …

Let Nutrition Be Your Vaccine Amid Covid-19- A Narrative Review, Vidya Rajesh

Manipal Journal of Medical Sciences

There has been a growing body of evidence highlighting the radical effect of nutrition on the immune system and disease susceptibility. The current COVID-19 crisis awakens an urgent calling for optimum nutrition which boosts immunity and prevents diseases, just like a vaccine. Though there have been several national guidelines regarding diet during COVID-19, there has been sparse research and literature available in this field. This review aims to summarise the existing evidence on various aspects of nutrition and immunity pertaining to the COVID-19 crisis. Literature and search strategy included PubMed and Google Scholar for articles on various aspects of nutrition …

Digital Revolution During Covid-19 Era, Monalisa Biswas

Manipal Journal of Medical Sciences

Triaging is of utmost importance in any pandemic and is essential in the present COVID-19 times when we are witnessing an enormous number of our population being affected by the novel coronavirus. Further, it is important to acknowledge the varied spectrum of manifestations among our patients with each patient needing a tailored protocol and facilitating in gaining an understanding of the epidemiology and disease pathophysiology. The rapid spread of COVID-19 and shortage of health care personnel in a developing country like India needs immediate and effective health technology to triage COVID suspects thereby reducing doctor – suspects’ contact and monitor …

“Sampark Snehi”: Telemedicine Consultation In Covid-19 Times At A Private Medical College Hospital – Digitalised Solution, Vijetha Belle

Manipal Journal of Medical Sciences

Every life is precious and every patient matters: In a country with 5.5 government beds for 10,000 population, even a marginal increase in hospitalization increases the pressure on the system exponentially. The spread of COVID-19 has kindled the need for transformation from traditional face-to-face doctorpatient communication to a telehealth platform. During the lockdown, reduced access to both outpatient and hospitalization services is proving to be fatal for countless non-covid patients. Taking lead in addressing the health care needs and demands of the society we cater to, E-consultation which has been initiated by most of the medical colleges providing tertiary care, …

Post-Partum Haemorrhage - The Ultimate Challenge To Emergency Medicine, Akshata Ammembal

Manipal Journal of Medical Sciences

Post-partum haemorrhage (PPH) is a leading cause of maternal mortality globally. This report elaborates the diagnosis and treatment of a 31-year-old woman with PPH, treated in our tertiary centre. On presentation, she showed all signs of hypovolemic shock and disseminated intravascular coagulation (DIC). Persistent fresh vaginal bleeding led to the decision to perform an emergency hysterectomy. She required massive transfusion but consequently developed transfusion-associated lung injury (TRALI), for which she was effectively treated. She made a full recovery leading to discharge 12 days after admission. This article stresses the importance of the multi-disciplinary approach and rapid, coordinated management of emergency …

Metastatic Genital Crohn’S Disease: Visceral Devil In The Details- A Case Report, Soumya Kanti Datta

Manipal Journal of Medical Sciences

Crohn’s disease (CD) is a chronic inflammatory bowel disease (IBD) commonly associated with extraintestinal manifestations such as arthritis, uveitis, deep venous thrombosis and erythema nodosum. Asymmetrical labial swelling and edema are the most common presentations of genital CD in females. Vulval CD can appear before or after gastrointestinal (GI) CD or it may occur simultaneously with an independent course of disease and response to treatment. Here we discuss an atypical case of metastatic vulvar CD presenting as perineal and perianal ulcers and erosions successfully treated with oral doxycycline and topical corticosteroids hence making it an exciting new treatment avenue to …

Antifungal Activity Of Polyscias Scutellaria Fosberg Leaves Against Candida Albicans, Nada Marcha Putri, Jasmine Regita Putri, Berna Elya, Robiatul Adawiyah

Pharmaceutical Sciences and Research

Polyscias scutellaria Fosberg is one of the indigenous plants from Indonesia that widely used as folk medicines for several illnesses. The leaves of P. scutellaria were previously studied as an antimicrobial agent. Nonetheless, this theory of antifungal activity has never been scientifically verified. This study aimed to evaluate the antifungal activity of P. scutellaria against Candida albicans. The leaves of P. scutellaria were macerated using an ethanol solvent. Then, the extract was evaporated and dissolved by 1% DMSO into different concentrations (100 μg/mL, 200 μg/mL, 400 μg/mL, 800 μg/mL, 1600 μg/mL, 3200 μg/mL, and 6400 μg/mL). Fluconazole, as a …

Inhibitory And Anti-Biofilm Effects Of Orthoshipon Aristatus Against Candida Albicans, Ratika Rahmasari, Ananda Hanny Chairunissa, Marina Ika Irianti, Roshamur Cahyan Forestrania, Ayun Erwina Arifianti, Herman Suryadi, Juliann Nzembi Makau, Ibrahim Jantan, Berna Elya

Pharmaceutical Sciences and Research

There are increasing number of reports on Candida albicans developing resistance to available anti-fungal drugs. Thus, there is an urgent need to discover new agents for treatment of candidiasis. The alcoholic extracts of Orthoshipon aristatus have been shown to exhibit antifungal activity against C. albicans by using the agar diffusion and broth microdilution methods. However, the underlying mechanisms of anti-C. albicans effect of O. aristatus have not been well understood. This study was aimed to evaluate the cytotoxic and anti-biofilm effects of the n-hexane and ethanol extracts of purple and white varieties of O. aristatus leaves …

Removal Of Mimosine From Leucaena Leucocephala (Lam.) De Wit Seeds To Increase Their Benefits As Nutraceuticals, Sri Wardatun, Yahdiana Harahap, Abdul Mun'im, Fadlina Chany Saputri Dr., Noorwati Sutandyo

Pharmaceutical Sciences and Research

The Leucaena leucocephala (Lam.) de Wit tree contains pharmacologically active compounds and can easily be found in abundant quantities. The utilization of this tree as a source of nutraceuticals would increase its value. The extraction yields show the number of compounds that have been extracted by solvent. However, Leucaena leucocephala (Lam.) de Wit seeds also contain mimosine, which can cause hair loss. The present study investigated the process of removing mimosine from the seeds. Three treatments were applied to these seeds: treatment without soaking, soaking with distilled water for 24 hours, and splitting the seeds in half and then soaking …

Antioxidant And Antiaging Assays Of Ageratum Conyzoides (L.) Ethanolic Extract, Afifah B. Sutjiatmo, Novi Edriayani, Tira Endang Mulyasari, Faizal Hermanto, M. Fahrauk, Elin Y. Sukandar, Hanna Sari Widya Kusuma, Rizal Rizal, Wahyu Widowati

Pharmaceutical Sciences and Research

The declining ability of tissues to repair or replace themselves and maintain their structure and normal function is called aging. Aging is caused by free radical that can induce the activation of elastase and collagenase. Ageratum conyzoides (L.) or known as Babadotan is a medicinal plant that has been reported to be a good source of antioxidants that also inhibit aging process. The purpose of this research is to evaluate the antioxidant and antiaging properties of Babadotan Ethanolic Extract (BEE). Franswoth method was used to determine the phytochemical assay of BEE. Measurement of 2,2-diphenyl 1-picrylhydrazyl (DPPH) scavenger was used for …

The Legacy Of Racism And Covid-19, Adedayo Okanlawon

MEDI 9331 Scholarly Activities Clinical Years

This perspective piece discusses the interplay between Covid-19, the legacy of racism in America, and their synergistic effects on the black community. Personal racially charged experiences in conjunction with notable stories of injustice in medicine are used to set the stage. The pandemic's disparate impact on black communities are then discussed with suggestion on how to mitigate these issues.

Preconceptional Lipid-Based Nutrient Supplementation In 2 Low-Resource Countries Results In Distinctly Different Igf-1/Mtor Placental Responses, Marisol Castillo-Castrejon, Ivana V. Yang, Elizabeth J. Davidson, Sarah J. Borengasser, Purevsuren Jambal, Jamie Westcott, Jennifer F. Kemp, Ana Garces, Sumera Aziz Ali, Sarah Saleem

Community Health Sciences

Background: Preconceptional maternal small-quantity lipid-based nutrient supplementation (SQLNS) improved intrauterine linear growth in low-resource countries as demonstrated by the Women First Preconception Maternal Nutrition Trial (WF). Fetal growth is dependent on nutrient availability and regulated by insulin-like growth factor 1 (IGF-1) through changes in placental transfer capacity, mediated by the mechanistic target of rapamycin (mTOR) pathway.
Objectives: Our objective was to evaluate the role of placental mTOR and IGF-1 signaling on fetal growth in women from 2 low-resource countries with high rates of stunting after they received preconceptional SQLNS.
Methods: We studied 48 women from preconception through delivery who were …

Tumor Necrosis Factor Alpha Snp Variant In Promoter Region G308a, Cause Preeclampsia During Pregnancy In Pakistani Women, A Case Control Study, Azizah Ziauddin, Sadia Ahmad, Asad Iqbal, Abdul Majid Khan, Shahid Mahmood Baig

Journal of Bioresource Management

Preeclampsia (PE) is a very common critical condition during pregnancy. As PE is a high-risk condition during pregnancy, occurring in 25% of all pregnancies, worldwide. In women with PE there is an increase in hypertension and albuminuria. Elevated blood pressure can be life-threatening after 20^th week of pregnancy. Single nucleotide variation in gene sequence can be disease causing, among these pathogenic SNPs, a variant in TNF-α, G308A is analyzed in many studies as a causative variant to cause preeclampsia. In this case control study fifty patients and fifty healthy individuals were enrolled for analysis of TNF-α promoter region …

Research News. Publications, 2020. Volume 4, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period October 1 through December 31, 2020

Sources Of Nutrition Information In Recreational Ultra-Marathon Runners: A Mixed Methods Analysis, Sara E. Mahoney, Thomas R. Wójcicki, Andrew J. Carnes

Journal of Human Performance in Extreme Environments

Ultra-marathon events (i.e., .42.2-km) continue to grow in popularity; however, little is known regarding the sources of nutrition information which inform their beliefs and habits. The objective of this study was to characterize the acquisition of sport-specific nutrition information among ultra-endurance athletes using a mixed methods design. Qualitative data were collected through focus groups and analyzed using thematic analysis. Three primary higher order themes were identified: Optimal Diet for Ultra-Endurance Athletes, Common Sources of Information, and Barriers to Scientific Information. Then, a self-report inventory (Sources of Nutrition Information-SONI questionnaire) was developed to assess common sources of nutrition information and characterize …

Fluoroscopic Demonstration Of Thoracic Tumor Immobilization With High Frequency Percussive Ventilation, Ina M Sala, Beverly Maurer, Cristian Solano, Ronald Levitin, Thomas M Guerrero

Articles

Purpose: The purpose of this first-in-man study is to directly measure thoracic tumor immobilization by high frequency percussive ventilation (HFPV).

Methods: In an IRB approved protocol (IRB # 2017-046) we screened patients with conspicuous lung tumors that exhibited motion >10 mm to undergo kV fluoroscopy with HFPV. Two sets of consecutive AP (anterior posterior) fluoroscopy frames were acquired during multiple breathing cycles for free- and HFPV- breathing. All images were acquired using our kV source/panel of the therapeutic linear accelerator. Percussions were delivered via the intrapulmonary percussive ventilation device (IPV-2C) and phasitron (Percussionaire Corp., Sagle, Idaho). The baseline settings for …

Community Engagement In Covid-19 Responses: Evidence From Qualitative Interface With Community Opinion Leaders In Enugu, Nigeria, Prince Agwu, Chinweoke Methodius Ugwu, Chidera Florence Eke

ASEAN Journal of Community Engagement

Successful stories of community engagement existed during the Ebola disease outbreak in Liberia, indicating that a combination of government and community efforts are needed in addressing pandemics or epidemics. However, for communities to rise to the challenge of containing and combatting the spread of any disease, they must be communicated most effectively and supported by the government. Therefore, our study investigates how applicable successful community engagement has been in the charge against the Coronavirus disease 2019 (COVID-19) in Nigeria. Through telephone interviews, we sourced data from 12 community opinion leaders in Enugu State, Nigeria. After conducting a thematic analysis of …

The 21st Century Global Digital Economies Revolution And The Aftermath Of Covid-19 Pandemic: Some Anticipated Implication Changes For Developing Nations, Agyei Fosu

ASEAN Journal of Community Engagement

The 21^st century digital global economies era changed developmental approaches drastically to a point where most researchers, policy makers, and developers have asserted that to achieve economic development for developing nations; it is paramount for Information and Communications Technologies (ICTs) investments in all sectors contributing to their economy. The current COVID-19 pandemic and the various measures taken by governments such as lockdown, curfew, companies asking employees to work from home, and the use of e-learning by schools to curb the disease brings into perspective the assertion raised by various scholars about the need for developing nations to invest in …

Training Program To Support Posbindu Cadre Knowledge And Community Health Centre Staff In The Geriatric Nutrition Service, Fatmah Fatmah

ASEAN Journal of Community Engagement

The geriatric minimal service standard (SPM) coverage in Depok has steadily decreased from 37.53% in 2013 to 11.8% in 2018. One factor affecting the problem is a lack of patient participation and the inability of posbindu (integrated service post for older people) cadres to perform their tasks. To increase the coverage of older people visiting posbindu, it is necessary to raise the knowledge and skill levels of posbindu cadres and community health centre staff in Depok. The skills include performing nutritional status assessment (NSA) and screening, early detection of dementia, independence assessment, and elderly nutrition counselling. This is a …

Therapeutics Development For Pseudoxanthoma Elasticum And Related Ectopic Mineralization Disorders: Update 2020., Hongbin Luo, Qiaoli Li, Yi Cao, Jouni Uitto

Department of Dermatology and Cutaneous Biology Faculty Papers

Pseudoxanthoma elasticum (PXE), the prototype of heritable ectopic mineralization disorders, manifests with deposition of calcium hydroxyapatite crystals in the skin, eyes and arterial blood vessels. This autosomal recessive disorder, due to mutations in ABCC6, is usually diagnosed around the second decade of life. In the spectrum of heritable ectopic mineralization disorders are also generalized arterial calcification of infancy (GACI), with extremely severe arterial calcification diagnosed by prenatal ultrasound or perinatally, and arterial calcification due to CD73 deficiency (ACDC) manifesting with arterial and juxta-articular mineralization in the elderly; the latter disorders are caused by mutations in ENPP1 and NT5E, respectively. The …

Impact Of The Covid-19 Pandemic On Mental Health And Well-Being Of Communities: An Exploratory Qualitative Study Protocol, Anam Shahil Feroz, Naureen Akber Ali, Noshaba Akber Ali, Ridah Feroz, Salima Nazim Meghani, Sarah Saleem

Community Health Sciences

Introduction: The COVID-19 pandemic has certainly resulted in an increased level of anxiety and fear in communities in terms of disease management and infection spread. Due to fear and social stigma linked with COVID-19, many individuals in the community hide their disease and do not access healthcare facilities in a timely manner. In addition, with the widespread use of social media, rumours, myths and inaccurate information about the virus are spreading rapidly, leading to intensified irritability, fearfulness, insomnia, oppositional behaviours and somatic complaints. Considering the relevance of all these factors, we aim to explore the perceptions and attitudes of community …

Pathogenesis And Onset Of Tinnitus And Use Of Holistic And Traditional Audiological Approaches For Management, Christy Mahrt, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Introduction: Tinnitus is the subjective sensation of noise perceived at the peripheral or central level. Occasionally, tinnitus perception may be severe enough to present debilitating effects on daily activities. The occurrence of tinnitus can be related to occupational or non-occupational hazardous noise exposure. Case Presentation: A 60-year-old male presented with bilateral tinnitus with an initial onset at age 21. The progression of his tinnitus has caused disruptions in sleeping patterns and concentration. His history included extensive occupational and non-occupational noise exposure. Discussion: Hearing conservation is an important aspect of facilitating tinnitus management for individuals who have noise-related tinnitus. Hearing aids, …

Cutaneous Candidiasis Mimicking Inverse Psoriasis Lesion In A Type 2 Diabetes Mellitus Patient, Steven Philip Surya, Kardiana Purnama Dewi, Regina Regina

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Type 2 diabetes mellitus (T2DM) condition could affect the skin. The disease is among the greatest risk factors of skin infection such as cutaneous candidiasis and is also associated with autoimmune skin diseases such as psoriasis, which lesion morphologies and predilection areas are quite similar. These similarities are a source of confusion to clinicians.

Case illustration: We present a 60-year-old female patient with uncontrolled T2DM and multiple erythematous plaques in the form of shiny lesions at the intertriginous area that developed 1 week prior to her hyperglycemic state. The lesions had recurred at the same site for …

Secondary Syringomyelia After Subarachnoid Hemorrhage: A Casereport, Shih-Shin Huang, Yen-Liang Ke, Wei-Chi Hsieh, Hung-Chih Hsu, Chien-Min Chen

Rehabilitation Practice and Science

Background: Cerebral artery aneurysm rupture is one of the common causes of subarachnoid hemorrhage. Patients with subarachnoid hemorrhage may have some degree of neurological defects and impairment on activity of daily living. Syringomyelia refer to the cavity formation in spinal cord. Possible etiologies may include congenital and acquired types. Patients with syringomyelia may suffer from limb pain and paresthesia. According to previous studies, secondary syringomyelia due to subarachnoid hemorrhage was not common. Hence, a case with syringomyelia secondary to subarachnoid hemorrhage was presented by introducing the clinical signs and image findings. Moreover, current literatures about syringomyelia secondary to subarachnoid hemorrhage …

Prevalence Of Nail Changes In Patients Infected With Hiv - A Cross Sectional Study, Seethalakshmi Ganga Vellaisamy, Priya Jeyaraman, Kannan Gopalan

Journal of General - Procedural Dermatology and Venereology Indonesia

Introduction: The spectrum of nail changes is wider and their frequency is higher among HIV patients. These changes magnify the range and multiplicity of AIDS manifestations. Their systematic examination is a non-invasive method of possible diagnostic value.

Objective: The present study was conducted to study the frequency and types of nail changes in  HIV infected individuals and to correlate the severity of nail changes  with CD4 count.

Material and Method: This was a cross sectional study, conducted in Skin & STD Out-Patient department in a tertiary care hospital between March 2018 and April 2019. A total of …

The Management Of Seborrheic Dermatitis 2020, Sandra Widaty, Kusmarinah Bramono, Muhammad Yulianto Listiawan, Ariyati Yosi, Eliza Miranda, Githa Rahmayunita, Herwinda Brahmanti, Henry W. Lim

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Seborrheic dermatitis (SD) is a chronic relapsing dermatitis manifesting in the seborrheic area, affecting infants or adults. In Indonesia, the prevalence of SD is 0.99–5.8% of all dermatology cases from 2013 to 2015. SD has been known to be a prominent manifestation among HIV patients, but there is an increasing trend in the general population. Therefore, in 2017, the Indonesian Society for Dermatology and Venereology proposed a consensus for the management of SD in Indonesia based on the discussion from 12 dermatological centers. Concurrent with the development of new drugs, this study aims to evaluate and develop a …

Reversal Reaction With Nodules Clinical Manifestations That Initially Diagnosed As Erythema Nodosum Leprosum In Borderline Lepromatous Leprosy, Laila Tsaqilah, Pati Aji Achdiat, Hendra Gunawan

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The reversal leprosy reaction generally manifest as larger, swollen, red and shiny the pre-existing skin lesions which are accompanied with pain. This reaction can be manifest as infiltration and nodules which resembles the features of erythema nodosum leprosum (ENL) leprosy reaction.

Case Illustration: We present a case of 26-year-old woman with erythematous nodules on almost all the body since two weeks ago. She had pre-existing erythema plaque on the right elbow became more erythematous and arouse with partially felt pain, fever, and malaise. Nodule lesions in BL leprosy with reaction need to be distinguished between ENL and …

Use Of A Cancer Registry To Evaluate Patient-Reported Outcomes Of Immune Checkpoint Inhibitors., Heather S L Jim, Sarah L Eisel, Aasha I Hoogland, Sandra Shaw, Jennifer C King, Adam P Dicker

Department of Radiation Oncology Faculty Papers

Immune checkpoint inhibitors (ICIs) are increasingly used for advanced lung cancer, butfew studies have reported on patient-reported outcomes (PROs) outside the context of a clinicaltrial. The goal of the current study was to assess PROs in participants of a lung cancer registry whohad been treated with an ICI. Patients participating in the GO2Foundation’s Lung Cancer Registrywho reported receiving atezolizumab, durvalumab, nivolumab, or pembrolizumab were invited toparticipate in a survey about their experiences during treatment. Quality of life was evaluated usingthe Functional Assessment of Cancer Therapy–General (FACT-G). Common symptomatic adverseevents were evaluated using an item bank generated for ICIs. Internationally, 226 …