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2020

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Articles 16591 - 16620 of 20660

Full-Text Articles in Medicine and Health Sciences

Increased Motor Vehicle Fatalities Tuesday Through Thursday During The Us Thanksgiving Holiday (1980-2018), Kendra Ratnapradipa, Motao Zhu Jan 2020

Increased Motor Vehicle Fatalities Tuesday Through Thursday During The Us Thanksgiving Holiday (1980-2018), Kendra Ratnapradipa, Motao Zhu

Journal Articles: Epidemiology

Traffic crashes remain a leading cause of death in the United States; holidays are known to have increased travel and traffic fatalities. Our purpose was to determine which days during Thanksgiving had the highest crash fatality risk compared to non-holiday periods. Using time series and binomial approximations, we analyzed Fatality Analysis Reporting System data (1980-2018) with a Monday-Sunday holiday and matching comparisons the weeks before and after. Fatalities included 31,263 during the holiday, 30,361 the previous week, and 29,399 the following week. Deadliest days during the holiday were Saturday (16.7% of fatalities) and Wednesday (16.0%), but odds of a traffic …


Sildenafil For The Treatment Of Alzheimer’S Disease: A Systematic Review, Owen Sanders Jan 2020

Sildenafil For The Treatment Of Alzheimer’S Disease: A Systematic Review, Owen Sanders

OHSU-PSU School of Public Health Faculty Publications and Presentations

Nitric oxide/cyclic guanosine monophosphate (cGMP) signaling is compromised in Alzheimer’s disease (AD), and phosphodiesterase 5 (PDE5), which degrades cGMP, is upregulated. Sildenafil inhibits PDE5 and increases cGMP levels. Integrating previous findings, we determine that most doses of sildenafil (especially low doses) likely activate peroxisome proliferator-activated receptor-γ coactivator 1α (PGC1α) via protein kinase G-mediated cyclic adenosine monophosphate (cAMP) response element binding protein (CREB) phosphorylation and/or Sirtuin-1 activation and PGC1α deacetylation. Via PGC1α signaling, low-dose sildenafil likely suppresses β-secretase 1 expression and amyloid-β (Aβ) generation, upregulates antioxidant enzymes, and induces mitochondrial biogenesis. Plus, sildenafil should increase brain perfusion, insulin sensitivity, long-term potentiation, …


Commercial Genetic Testing For Type 2 Polysaccharide Storage Myopathy And Myofibrillar Myopathy Does Not Correspond To A Histopathological Diagnosis, Stephanie J. Valberg, C. J. Finno, Marisa L. Henry, Melissa Schott, Deborah Velez-Irizarry, Sichong Peng, Erica C. Mckenzie, Jessica L. Petersen Jan 2020

Commercial Genetic Testing For Type 2 Polysaccharide Storage Myopathy And Myofibrillar Myopathy Does Not Correspond To A Histopathological Diagnosis, Stephanie J. Valberg, C. J. Finno, Marisa L. Henry, Melissa Schott, Deborah Velez-Irizarry, Sichong Peng, Erica C. Mckenzie, Jessica L. Petersen

Department of Animal Science: Faculty Publications

Background: Commercial genetic tests for type 2 polysaccharide storage myopathy (PSSM2) and myofibrillar myopathy (MFM) have not been validated by peer-review, and formal regulation of veterinary genetic testing is lacking.

Objectives: To compare genotype and allele frequencies of commercial test variants (P variants) in MYOT (P2; rs1138656462), FLNC (P3a; rs1139799323), FLNC (P3b; rs1142918816) and MYOZ3 (P4; rs1142544043) between Warmblood (WB) and Arabian (AR) horses diagnosed with PSSM2/MFM by muscle histopathology, and phenotyped breed-matched controls. To quantify variant frequency in public repositories of ancient and modern horse breeds.

Study design: Cross sectional using archived clinical material and publicly available data.

Methods: …


Validity Of Plasma Collection Cards For Ferritin Assessment—A Proof-Of-Concept Study, Karsten Koehler, Eileen Marks-Nelson, Camila Pereira Braga, Safiya E. Beckford, Jiri Adamec Jan 2020

Validity Of Plasma Collection Cards For Ferritin Assessment—A Proof-Of-Concept Study, Karsten Koehler, Eileen Marks-Nelson, Camila Pereira Braga, Safiya E. Beckford, Jiri Adamec

Department of Biochemistry: Faculty Publications

Objectives: Iron depletion is common around the world and among certain risk groups in developed countries. The overall purpose was to test the suitability of a novel plasma collection card for minimally invasive iron status assessment.

Methods: Twenty participants (10 f/10 m) participated in this cross-sectional study. Ferritin and hemoglobin were measured from blood collected from a forearm vein, serving as reference method. Blood was also collected from the fingertip using the NoviplexTM Plasma Prep Card as well as capillary collection tubes.

Results: There was substantial concordance between ferritin measured from samples collected via NoviplexTM and venous ferritin (concordance correlation …


Examining Spatial Accessibility To Covid-19 Testing Sites In Florida, Ran Tao, Joni Downs, Theresa M. Beckie, Yuzhou Chen, Warren Mcnelley Jan 2020

Examining Spatial Accessibility To Covid-19 Testing Sites In Florida, Ran Tao, Joni Downs, Theresa M. Beckie, Yuzhou Chen, Warren Mcnelley

All publications

Massive and rapid testing is crucial for containing the spread of COVID-19. Health and policy planners must ensure that access to and uptake of SARS-CoV-2 testing is adequate and equitable. This study measures the spatial accessibility to testing sites in Florida at the census tract level at the end of May 2020, using the 2-step floating catchment area method that integrates both driving and walking modes. Accessibility scores were found to be heterogeneous across geographic regions and among different groups of people. In particular, many rural areas were in a testing desert. While people in larger cities tended to have …


Screens, School District Employees, And Sleep: Is There A Relationship?, Mary Kay L. Bruihler Jan 2020

Screens, School District Employees, And Sleep: Is There A Relationship?, Mary Kay L. Bruihler

All Graduate Theses, Dissertations, and Other Capstone Projects

Statement of the Problem

Working in a school can be stressful and about half of educators in a national survey reported less than the recommended minimum of seven hours of sleep. Smartphones and other screened devices can cause sleep loss and are becoming more prevalent. Is there a relationship between the use of screened devices and sleep among the employees of a school district?

Procedures

Employees (n=36) of a small southern Minnesota school district were given an online survey regarding their sleep habits utilizing the Pittsburg Sleep Quality Index (PSQI), their screen time use, utilizing the Screen Time Questionnaire (STQ), …


The Difference In Barriers To Colorectal Cancer Screening Between Men And Women In The 45-55-Year Age Group, Maren Christina Davis Jan 2020

The Difference In Barriers To Colorectal Cancer Screening Between Men And Women In The 45-55-Year Age Group, Maren Christina Davis

All Graduate Theses, Dissertations, and Other Capstone Projects

Statement of the Problem: Adults, 50 years or older, should have a screening colonoscopy every ten years and fecal immunochemical test (FIT) every year. However, close to 22 million adults between the ages of 50-75 in the U.S. have never been screened for colorectal cancer, which delays treatment and can be fatal if the cancer is not found in time.

Procedure: This study used a descriptive, cross-sectional, survey-based design and a convenience sample of men and women between 45 and 55 years old to assess colorectal screening practices, barriers to screening, and knowledge levels about colorectal cancer screening.

Findings: A …


The Effect Of Acuity-Based Nurse Staffing On Nursing Medication Errors, Egidius Maria Eugene Waterval Jan 2020

The Effect Of Acuity-Based Nurse Staffing On Nursing Medication Errors, Egidius Maria Eugene Waterval

Electronic Theses and Dissertations, 2020-2023

Nurses spend on average one third of their time on direct patient care, and most on indirect care in hospital settings. However, nursing workload is challenging to measure in a systemized, accurate, and timely way. Patient classification systems are designed to capture information about nursing workload based on the illness severity of the patient (acuity) to determine staffing resources and balance nursing workload. These systems are instruments that group nursing care activities in different categories to determine patient acuity. Electronic health records provide opportunities to use available data sets to accurately, and in real-time, document many direct and indirect patient …


Medicine And Culture Abroad: Lago De Atitlan, Guatemala, Micah Helton Jan 2020

Medicine And Culture Abroad: Lago De Atitlan, Guatemala, Micah Helton

Posters

Describes her experience working alongside a Guatemalan General Practice Physician in Lago de Atitlan, Guatemala.


Distal Urogenital Anatomy Of Male Prairie Racerunners, Aspidoscelis Sexlineatus Viridis (Reptilia: Sauria: Teiidae), Stanley E. Trauth Jan 2020

Distal Urogenital Anatomy Of Male Prairie Racerunners, Aspidoscelis Sexlineatus Viridis (Reptilia: Sauria: Teiidae), Stanley E. Trauth

Journal of the Arkansas Academy of Science

I examined histologically the distal urogenital anatomy in male Prairie Racerunners (Aspidoscelis sexlineatus viridis) from a small seasonal sample of individuals collected in Arkansas in order to provide additional information regarding squamate urogenital anatomy. Specifically, I focused on the basic anatomy and positioning of posterior ducts and associated structures in this teiid lizard. The anatomical structures included the ductus deferens, ampulla ductus deferens, ampulla urogenital papilla (Aup), ureter, inner core tissue mass, urodaeum, and the urogenital papilla. The two Aup, which are small complimentary blind pouches representing the terminal repositories for products released by urogenital ducts, are striking …


Instructions To Authors, Academy Editors Jan 2020

Instructions To Authors, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.


Teriparatide, Hacen Vall, Mayur S. Parmar Jan 2020

Teriparatide, Hacen Vall, Mayur S. Parmar

HPD Articles

No abstract provided.


Human Papilloma Virus Vaccine, Lucia Soca Gallego, Alvio Dominguez, Mayur S. Parmar Jan 2020

Human Papilloma Virus Vaccine, Lucia Soca Gallego, Alvio Dominguez, Mayur S. Parmar

HPD Articles

No abstract provided.


Reserpine, Michelle Cheung, Mayur S. Parmar Jan 2020

Reserpine, Michelle Cheung, Mayur S. Parmar

HPD Articles

No abstract provided.


Fosinopril, Kaitlyn Alessi, Mayur S. Parmar Jan 2020

Fosinopril, Kaitlyn Alessi, Mayur S. Parmar

HPD Articles

No abstract provided.


Fluorescein, Amy-Grace Pothen, Mayur S. Parmar Jan 2020

Fluorescein, Amy-Grace Pothen, Mayur S. Parmar

HPD Articles

No abstract provided.


Dornase Alfa, Rida Altaf, Mayur S. Parmar Jan 2020

Dornase Alfa, Rida Altaf, Mayur S. Parmar

HPD Articles

No abstract provided.


Flucytosine, Inderbir S. Padda, Mayur S. Parmar Jan 2020

Flucytosine, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.


Lisinopril, Edgardo Olvera Lopez, Mayur S. Parmar, Venkata Satish Pendela, Jamie M. Terrell Jan 2020

Lisinopril, Edgardo Olvera Lopez, Mayur S. Parmar, Venkata Satish Pendela, Jamie M. Terrell

HPD Articles

No abstract provided.


Indinavir, Eliyah B. Pollak, Mayur S. Parmar Jan 2020

Indinavir, Eliyah B. Pollak, Mayur S. Parmar

HPD Articles

No abstract provided.


Lamivudine, Katherine Taylor, Kristina Fritz, Mayur S. Parmar Jan 2020

Lamivudine, Katherine Taylor, Kristina Fritz, Mayur S. Parmar

HPD Articles

No abstract provided.


Sodium Oxybate, Alvio Dominguez, Lucia Soca Gallego, Mayur S. Parmar Jan 2020

Sodium Oxybate, Alvio Dominguez, Lucia Soca Gallego, Mayur S. Parmar

HPD Articles

No abstract provided.


Pralidoxime, Rishab Gupta, Mayur S. Parmar Jan 2020

Pralidoxime, Rishab Gupta, Mayur S. Parmar

HPD Articles

No abstract provided.


Tolterodine, Shreya Narain, Mayur S. Parmar Jan 2020

Tolterodine, Shreya Narain, Mayur S. Parmar

HPD Articles

No abstract provided.


Appreciative Inquiry Of An Exemplary Trauma Informed Wellness Center Created For The Community And Families Affected By A School Shooting, Halle Solomon Jan 2020

Appreciative Inquiry Of An Exemplary Trauma Informed Wellness Center Created For The Community And Families Affected By A School Shooting, Halle Solomon

Department of Family Therapy Dissertations and Applied Clinical Projects

Gun violence has flooded our society with human-caused disasters, making mass shootings an unfortunate new normal. In the wake of large- scale shootings, the United States Government and other agencies provide financial support and resources to the affected community in hopes of bringing solidarity to the fractured system. This financial reinforcement and other funding sources have been utilized to build resiliency centers within a certain distance of the unnerving events. Resiliency facilities play a pivotal role in helping communities recover from human-caused disasters such as mass shootings. These resources are becoming customary across the country, with resiliency centers in Newton, …


Sin Papeles: The Experiences Of Undocumented Central American Immigrants In The United States, Elizabeth Jarquin Jan 2020

Sin Papeles: The Experiences Of Undocumented Central American Immigrants In The United States, Elizabeth Jarquin

Department of Family Therapy Dissertations and Applied Clinical Projects

In the United States, the topic of immigration represents a source of intense debate, which has escalated in recent years. Research indicates that Latinx immigrants are negatively impacted by current immigration policies— they are feeling afraid, angry, exhausted, defeated, overwhelmed, and concerned about themselves and their family (Castrellón, Rivarola, & López, 2017; Wray-Lake et al., 2018). This research, however, has largely neglected the Central American subgroup and the experiences of undocumented immigrants. The purpose of this study was to understand the experiences of undocumented Central American immigrants and their families within the current sociopolitical context. I utilized interpretative phenomenological analysis …


Happy Tears: An Evocative Autoethnography On An Adoptee’S Development Of Identity Through Reunification, Jessica Popham Jan 2020

Happy Tears: An Evocative Autoethnography On An Adoptee’S Development Of Identity Through Reunification, Jessica Popham

Department of Family Therapy Dissertations and Applied Clinical Projects

The story of adoption reunions is a story of many others. With the invention of the internet and DNA profiling websites, what was once impossible, or very difficult, is now as simple as submitting saliva to a DNA profiling company. This easier way to explore family backgrounds has created new experiences for adoptees. After a reunification, adoptees can reevaluate their identity with the new information to help develop a broader and deeper view of themselves (Henze-Pederson, 2019; Kiecolt & LoMascolo, 2003; Palmer, 2011; Schooler & Norris, 2002). In this study, I looked at how my adoptive identity changed after reunification …


Exploring The Professional Development Of Mft Students Enrolled In Equine Assisted Family Therapy Coursework: An Experiential Learning Modality, Natalie Rothman Jan 2020

Exploring The Professional Development Of Mft Students Enrolled In Equine Assisted Family Therapy Coursework: An Experiential Learning Modality, Natalie Rothman

Department of Family Therapy Dissertations and Applied Clinical Projects

Equine assisted activities have been utilized in various manners with multiple populations in therapeutic and educational environments. A graduate level marriage and family therapy program in South Florida is currently offering Equine Assisted Relational Learning (EARL) activities focused on teaching a specific sub-model of Equine Assisted Psychotherapy (EAP), known as Equine Assisted Family Therapy (EAFT). The experiential nature of EAP and EARL transforms abstract concepts such as thoughts and mannerisms into tangible experiences, as well as highlights behavioral patterns. The unique and innovative theoretical foundation of EAFT is being taught, demonstrated, and utilized to assist graduate level therapists with professional …


The Conundrum Of Both/And In A World Of Either/Or: An Interpretive Phenomenological Analysis Of Resilience And Intersectional Identities In Queer Women Of Afro-Caribbean Descent, Stephane Louis Jan 2020

The Conundrum Of Both/And In A World Of Either/Or: An Interpretive Phenomenological Analysis Of Resilience And Intersectional Identities In Queer Women Of Afro-Caribbean Descent, Stephane Louis

Department of Family Therapy Dissertations and Applied Clinical Projects

Queer people of color are more at risk for bias and brutality than other sexual or racial minority groups (Follins, Walker, & Lewis, 2014). Homophobic violence is embedded in Afro-Caribbean culture and even substantiated by some of those countries’ laws (Calixte, 2005). While more research is being increasingly done on LGBTQ+ black lived experiences, studies have focused more on discriminatory trauma than everyday triumph. Movements like Black Girls Rock (Bond, 2018) and intersectional black feminism (Nash, 2018) celebrate women of color surviving and thriving the compound effects of racism and sexism. In addition to misogynoir, this research gave consideration to …


The Impact Of Grief Work On Hospice Mental Health Providers Through A Bowen Family Systems Lens, Joshua Hernandez Jan 2020

The Impact Of Grief Work On Hospice Mental Health Providers Through A Bowen Family Systems Lens, Joshua Hernandez

Department of Family Therapy Dissertations and Applied Clinical Projects

Marriage and family therapists and other mental health professionals and clients can be thought of as their own, divine emotional unit, generating and distributing the anxiety of one to the other. In fact, Kerr and Bowen (1988) described anxiety as a driving force exchanged by every living organism, and the energy surrounded by every human relationship. Within a hospice setting, anxiety can be heightened due to catering to end-of-life care, which can potentially affect the emotional response and reactivity of the mental health professional, changing the course of treatment for the patient and their family. Emerging research within healthcare has …