Medicine and Health Sciences Commons^™

Reference Values For Certain Serum Biochemical Markers Of Liver Damage In Apparently Healthy Red Sokoto Goats, Patrick Emeka Aba, John Ikechukwu Ihedioha, Innocent Chima Nwaogu

The Thai Journal of Veterinary Medicine

The Red Sokoto goat (RSG) is the most preponderant of all the breeds of goats in Nigeria. There is dearth of information regarding the reference values for serum biochemical markers of liver damage in this breed. This study demonstrated the reference values in apparently healthy RSG and in RSG that were truly negative for liver disorders. The study was a cross sectional survey. Research visits were made to Ikpa Market Abattoir, Nsukka, for 12 weeks. Apparently healthy goats and those truly negative for liver disorders were deliberately selected for the study. Blood samples were collected in sample bottles devoid of …

Effects Of Copper-Bearing Montmorillonite On Salmonella Spp. In Vitro Study, Chiu-Huang Ting, Shih-Chu Chen, Ching-Dong Chang, Wen-Ling Shih, Perng-Chih Shen, Hung-Yi Wu

The Thai Journal of Veterinary Medicine

Clay is an important material available in nature. Montmorillonite is considered viable for producing enhanced performance in a variety of materials and products. Farmed animals such as pigs and poultry receive additional Zn and Cu in their diets as supplements in their compound feed and these elements are also used for medical remedies. This study aimed to observe the bactericidal activity of copper-bearing montmorillonite (Cu-MMT) against Salmonella spp. in vitro. The experiments were divided into two methods that effect Salmonella spp.. First, Cu-MMT was used to precipitate the Cu2+ ion supernatant mixed with bacteria. The second, Cu-MMT was directly mixed …

Molecular And Antigen Detection Of Dirofilaria Immitis Infection In Client-Owned Cats In Bangkok, Thailand, Sukullaya Ritthikulprasert, Pipat Jirapiti, Siwaporn Pengpis

The Thai Journal of Veterinary Medicine

Feline heartworm disease, caused by Dirofilaria immitis infection, can be potentially fatal to cats. Screening for the infection in cats is important in endemic areas. Clinical utility of molecular techniques for diagnosis of feline heartworm disease is not clearly determined. The objective of this study was to evaluate whether a polymerase chain reaction (PCR) assay could be used for detection of D. immitis infection in cats that were concurrently tested for D. immitis antigen. Blood samples were collected from 100 client-owned cats in a veterinary teaching hospital. Whole blood samples were tested for D. immitis antigen and extracted for total …

Use Of Ultrasound In A Case Of Actinomycosis In A Holstein Friesian Cow, Alessio Madrigali, Francesca Bonelli, Micaela Sgorbini, Simonetta Citi, Carlo Cantile, Filippo Fratini, Luca Turini

The Thai Journal of Veterinary Medicine

Actinomycosis is a sporadic disease of cattle, caused by Actinomyces bovis. In presence of oral injuries or openings, A. bovis could penetrate tissues and infect maxilla or mandible bones. A Holstein Friesian cow was presented for inappetence, weight loss and a left-sided mandibular swelling. A unilateral swelling was visible on the left jaw as a ventro-lateral and circular in shape. A fine-needle aspiration was collected. Ultrasonography examination was performed. Bacteriological analysis was negative. Due to the history, actinomycosis diagnosis was suggested and the cow was culled. Pathological examination revealed lesions indicative of chronic pyogranulomatous mandibular osteomyelitis with intralesional colonies of …

Juvenile Diabetes Mellitus With Exocrine Pancreatic Insufficiency In A Thai Bangkaew Dog: A Case Report, Jeerawat Soonthornsit, Weerachai Anpranit

The Thai Journal of Veterinary Medicine

An 8-month-old intact male Thai Bangkaew bred dog presented with polyuria, polydipsia, polyphagia, exercise intolerance and weight loss over 2 weeks. The serum biochemistry profiles revealed hyperglycemia, glycosuria and high serum fructosamine concentrations indicating the development of diabetes mellitus. The dog had a good response to a half-dose of intermediate-insulin injection twice daily monitored by the improvement of clinical signs and serum fructosamine. This was supposed to be due to the partial destruction of islets of Langerhans. Two months later, voluminous diarrhea with greasy stools, dry coat hair and generalized alopecia were observed. However, the clinical signs of diabetes mellitus, …

Immediate Changes In Hemodynamics And Gas Exchange After Initiation Of Noninvasive Ventilation In Cardiac Surgical Patients, Mohammad Hamid, Mohammad Irfan Akhtar, Saba Ahmed

Department of Anaesthesia

Introduction: Cardiac surgery is associated with pulmonary dysfunction and complications such as prolonged intubation and reintubation. Bilevel positive airway pressure (BiPAP) machine has been used in the clinical settings to improve oxygenation, reduce work of breathing, and avoid reintubation. The effect of BiPAP on cardiovascular parameters is not well established, and very few studies have targeted hemodynamic changes. The aim of the study was to assess the immediate effect of BiPAP on respiratory and hemodynamic parameters in post-cardiac surgery patients.
Materials and methods: This quasi-experimental study was done on 33 adult cardiac surgery patients. Ethical review committee approval was sought …

Mechanistic Assessment Of Functionalized Mesoporous Silica-Mediated Insulin Fibrillation, Mohsen Akbarian, Lobat Tayebi, Soliman Mohammadi-Samani, Fatemeh Farjadian

School of Dentistry Faculty Research and Publications

Insulin, which is a small protein hormone consisting of 51 amino acids, rapidly fibrillates under stressogenic conditions. This biotechnological/ medical problematic reaction quickly accelerates in the presence of some particles, while there are several other particles that slow down the kinetic process. To address the unexplored demand of the particles that modulate protein fibrillation, we have synthesized two amino-based particles and a chitosan-coated mesoporous silica particle (MS-NH₂, MS-3NH₂, and MS-chitosan) to investigate insulin fibrillation. While these particles were fairly similar in size, they are differ in their net positive charge and surface hydrophobicity. To monitor the …

Directors’ Duties Of Financially Distressed Companies In The Time Of Covid-19, Aurelio Gurrea-Martinez

Research Collection Yong Pung How School Of Law

Unlike other jurisdictions around the world, several European countries require corporate directors to file for bankruptcy once a company becomes insolvent. For instance, under German law, corporate directors are required to file for bankruptcy within three weeks since they know, or ought to have known, that the company became insolvent on a balance-sheet or a cash-flow basis. Failure to comply with this duty may expose the directors to both civil and criminal liability. In Spain, a similar duty is imposed. However, instead of exposing directors to criminal liability, they can be subject to other sanctions (including disqualification and liability for …

A Meta-Synthesis Of The American And The European Standards For The Accreditation Of Counseling Training Programs, Natalia Zapolsky

Dissertations

The purpose of this qualitative study was to explore how the European Standards for the accreditation of counseling training programs compare to CACREP standards and to each other. The differences and commonalities between standards have been defined through a meta-synthesis of integrated findings from a large body of inter-related qualitative studies and reinterpretation of the synthesized data.

This qualitative meta-synthesis research was intended to contribute to the process of counseling globalization by exploring the unique cultural features and aspects of the European and the U.S. accrediting systems for counseling training programs. This research revealed 1) the commonly recognized areas that …

Rural Definition Consistency Among U.S. Veteran Studies: A Rapid Review Of The Literature, Jed Hansen, Abbey Klein, Christine Eisenhauer, Marcia Shade

Posters and Presentations: College of Nursing

No abstract provided.

Cognitive Impairment From Early To Middle Adulthood In Patients With Affective And Nonaffective Psychotic Disorders, Josephine Mollon, Samuel R. Mathias, Emma Knowles, Amanda Rodrigue, Marinka M. G. Koenis, Godfrey D. Pearlson, Abraham Reichenberg, Jennifer Barrett, Dominique Denbow, Katrina Aberizk, Molly Zatony, Russell A. Poldrack, John Blangero, David C. Glahn

School of Medicine Publications

Background.—Cognitive impairment is a core feature of psychotic disorders, but the profile of impairment across adulthood, particularly in African-American populations, remains unclear.

Methods.—Using cross-sectional data from a case–control study of African-American adults with affective (n = 59) and nonaffective (n = 68) psychotic disorders, we examined cognitive functioning between early and middle adulthood (ages 20–60) on measures of general cognitive ability, language, abstract reasoning, processing speed, executive function, verbal memory, and working memory.

Results.—Both affective and nonaffective psychosis patients showed substantial and widespread cognitive impairments. However, comparison of cognitive functioning between controls and psychosis groups throughout early …

Health Of Special Immigrant Visa Holders From Iraq And Afghanistan After Arrival Into The United States Using Domestic Medical Examination Data, 2014-2016: A Cross-Sectional Analysis., Gayathri S Kumar, Clelia Pezzi, Simone Wien, Blain Mamo, Kevin Scott, Colleen Payton, Kailey Urban, Stephen Hughes, Lori Kennedy, Nuny Cabanting, Jessica Montour, Melissa Titus, Jenny Aguirre, Breanna Kawasaki, Rebecca Ford, Emily S Jentes

Department of Family & Community Medicine Faculty Papers

BACKGROUND: Since 2008, the United States has issued between 2,000 and 19,000 Special Immigrant Visas (SIV) annually, with the majority issued to applicants from Iraq and Afghanistan. SIV holders (SIVH) are applicants who were employed by, or on behalf of, the US government or the US military. There is limited information about health conditions in SIV populations to help guide US clinicians caring for SIVH. Thus, we sought to describe health characteristics of recently arrived SIVH from Iraq and Afghanistan who were seen for domestic medical examinations.

METHODS AND FINDINGS: This cross-sectional analysis included data from Iraqi and Afghan SIVH …

Bone Marrow Concentrate (Bmc) Therapy In Musculoskeletal Disorders: Evidence-Based Policy Position Statement Of American Society Of Interventional Pain Physicians (Asipp), Laxmaiah Manchikanti, Christopher J. Centeno, Sairam Atluri, Sheri L. Albers, Shane Shapiro, Gerard A. Malanga, Alaa Abd-Elsayed, Mairin Jerome, Joshua A. Hirsch, Alan David Kaye, Steve M. Aydin, Douglas Beall, Don Buford, Joanne Borg-Stein, Ricardo M. Buenaventura, Joseph A. Cabaret, Aaron K. Calodney, Kenneth D. Candido, Cameron Cartier, Richard Latchaw, Sudhir Diwan, Ehren Dodson, Zachary Fausel, Michael Fredericson, Christopher G. Gharibo, Mayank Gupta, Adam M. Kaye, Nebojsa Nick Knezevic, Radomir Kosanovic, Matthew Lucas, Maanasa V. Manchikanti, R. Amadeus Mason, Kenneth Mautner, Samuel Murala, Annu Navani, Vidyasagar Pampati, Sarah Pastoriza, Ramarao Pasupuleti, Cyril Philip, Mahendra R Sanapati, Theodore Sand, Rinoo V Shah, Amol Soin, Ian Stemper, Bradley W Wargo, Philippe Hernigou

School of Pharmacy Faculty Articles

BACKGROUND: The use of bone marrow concentrate (BMC) for treatment of musculoskeletal disorders has become increasingly popular over the last several years, as technology has improved along with the need for better solutions for these pathologies. The use of cellular tissue raises a number of issues regarding the US Food and Drug Administration's (FDA) regulation in classifying these treatments as a drug versus just autologous tissue transplantation. In the case of BMC in musculoskeletal and spine care, this determination will likely hinge on whether BMC is homologous to the musculoskeletal system and spine.

OBJECTIVES: The aim of this review is …

The Scoop, Vol. 6 Issue 12, March 2020, Health Sciences Library

Volume 6

Latest news and events from the Health Sciences Library in our monthly newsletter for March 2020.

Reversing Heart Failure With A Ventricular Anchoring Device: Another Hope For Myopathic Mitral Regurgitation., J. Eduardo Rame

Center for Translational Medicine Faculty Papers

No abstract provided.

Holistic Treatment Of Chronic Myeloid Leukaemia With Adjuvant Homoeopathic Therapy: A Case Report, R Shaji Kumar

Indian Journal of Research in Homoeopathy

Introduction: Chronic myeloid leukaemia (CML) is a clonal myeloproliferative disorder of haematopoietic stem cell. Case Summary: This is a case of a 28-year-old female having CML for 1½ years, on regular allopathic medication. The patient was suffering from ulceration in the oral cavity, frequent offensive loose stools with melena and prolonged menstrual cycle with heavy bleeding for 3 weeks. After analysing the constitutional make-up of the patient, Platinum metallicum 200C was prescribed. Over a period of 3 months, the patient reported improvement in weakness, nausea, sleeplessness, irritability, heavy menstruation, loose black stools and backache. Until the last follow-up while submitting …

Research Highlights (October 2019–December 2019), Anjula Narang

Indian Journal of Research in Homoeopathy

No abstract provided.

An Update On Bowel Nosodes With Comparisons, Laxmikanta Nanda

Indian Journal of Research in Homoeopathy

No abstract provided.

Analysis On Addiction And Opioid Crisis: Implications And Solutions, Bhavika Korat

Electronic Theses, Projects, and Dissertations

Opioids have become a popular way of pain management treatment over the past decades and although they have proven to be very successful to treat pain, they require serious attention as they have become the cause of addiction and overdose deaths. Opioid overdose costs the US government $78.5 billion each year. This project exhibits the background on opioids, the different types of opioids and their role in the addiction and overdose epidemic. The objective behind this project was to demonstrate what kind of people are more vulnerable to addiction and overdose.

This project shows the statistics of opioid overdose deaths …

Direct Assessment Of Mental Health And Metabolic Syndrome Amongst Indonesian Adolescents: A Study Design For A Mixed-Methods Study Sampled From School And Community Settings, Peter S. Azzopardi, Lisa Willenberg, Nisaa Wulan, Yoga Devaera, Bernie Medise, Aida Riyanti, Ansariadi Ansariadi, Susan Sawyer, Tjhin Wiguna, Stanley Luchters

Population Health, East Africa

Non-communicable diseases (NCDs) are the leading cause of morbidity and mortality globally, with the burden largely borne by people living in low- and middle-income countries. Adolescents are central to NCD control through the potential to modify risks and alter the trajectory of these diseases across the life-course. However, an absence of epidemiological data has contributed to the relative exclusion of adolescents from policies and responses. This paper documents the design of a study to measure the burden of metabolic syndrome (a key risk for NCDs) and poor mental health (a key outcome) amongst Indonesian adolescents. Using a mixed-method design, we …

Cost-Effectiveness Analysis Of Ocriplasmin Versus Watchful Waiting For Treatment Of Symptomatic Vitreomacular Adhesion In The Us, Arshad M Khanani, Pravin U Dugel, Julia A Haller, Alan L Wagner, Benedicte Lescrauwaet, Ralph Schmidt, Craig Bennison

Wills Eye Hospital Papers

Aim: Evaluate the cost-effectiveness of ocriplasmin in symptomatic vitreomacular adhesion (VMA) with or without full-thickness macular hole ≤400 μm versus standard of care.

Methods: A state-transition model simulated a cohort through disease health states; assignment of utilities to health states reflected the distribution of visual acuity. Efficacy of ocriplasmin was derived from logistic regression models using Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole trial data. Model inputs were extracted from Phase III trials and published literature. The analysis was conducted from a US Medicare perspective.

Results: Lifetime incremental cost-effectiveness ratio was US$4887 per quality-adjusted life year gained …

Review/Overview Of Pain In Sickle Cell Disease., Samir K. Ballas, Deepika S. Darbari

Cardeza Foundation for Hematologic Research

Sickle cell disease (SCD) is a highly complex inherited disorder of hemoglobin structure. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing multiple phenotypic expressions that constitute the various complications of the disease. Its manifestations could be acute, chronic, nociceptive, neuropathic that could occur singly or in various combinations. Pain continues to be the major factor of SCD phenotypic complications and the most common cause of admissions to the Emergency Department and/or the hospital. Although progress has been made in understanding the pathophysiology of SCD as well as in developing curative therapies such …

Novel Elvitegravir Nanoformulation For Drug Delivery Across The Blood-Brain Barrier To Achieve Hiv-1 Suppression In The Cns Macrophages, Yuqing Gong, Pallabita Chowdhury, Prashanth K.B. Nagesh, Mohammad A. Rahman, Kaining Zhi, Murali M. Yallapu, Santosh Kumar

School of Medicine Publications

The use of antiretroviral therapy (ART) has remarkably decreased the morbidity associated with HIV-1 infection, however, the prevalence of HIV-1-associated neurocognitive disorders (HAND) is still increasing. The blood-brain barrier (BBB) is the major impediment for penetration of antiretroviral drugs, causing therapeutics to reach only suboptimal level to the brain. Conventional antiretroviral drug regimens are not sufficient to improve the treatment outcomes of HAND. In our recent report, we have developed a poloxamer-PLGA nanoformulation loaded with elvitegravir (EVG), a commonly used antiretroviral drug. The nanoformulated EVG is capable of elevating intracellular drug uptake and simultaneously enhance viral suppression in HIV-1-infected macrophages. …

Management Of Patients With Isolated Acute Cervical Carotid Artery Occlusion And Normal Neurological Exam: Technical Note And Case Series, Joshua H. Weinberg, Nohra Chalouhi, Ahmad Sweid, Stavropoula Tjoumakaris, Michael Reid Gooch, Robert H. Rosenwasswer, Pascal Jabbour, Hekmat Zarzour

Department of Neurosurgery Faculty Papers

Objectives

Limited data exists on the management and outcome of patients with isolated acute cervical internal carotid artery (cICA) occlusion presenting with normal neurologic exam after experiencing a period of neurological deficits. These patients are at risk for progressive neurologic deterioration but have not yet progressed to stroke. Current management is no intervention due to intervention risk of embolization. We aim to determine the optimal management of patients with isolated acute cICA occlusion presenting with a normal neurological exam after experiencing neurological deficits.

Patients and methods

Data was collected on 3 patients with acute cICA occlusion that presented with a …

The Bull Or The Horn - What Are Outcomes Data?, James Harrop

Department of Neurosurgery Faculty Papers

No abstract provided.

Apthous Ulcers, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Using A Critical Safety Behavior Scoring Tool For N95 Respirator Use To Evaluate Training Interventions, Elizabeth L. Beam, Kevin A. Kupzyk, Jocelyn J. Herstein, Shawn Gibbs

Posters and Presentations: College of Nursing

Background: Hospitals struggle nationally to educate healthcare workers on the safe use of N95 respirators as part of their respiratory protection programs. Practical and effective interventions are needed to improve this clinical behavior which is critical to healthcare worker safety in airborne precautions, hazardous drug administration, and pandemic response. This analysis specifically investigated two just-in-time training interventions that would be practical to implement in a hospital setting. Method: A simulation approach was used to evaluate two interventions for N95 respirator use at a Midwestern Academy Hospital system (n=62, 32 control, 30 treatment). Healthcare workers were asked to don and doff …

Clinical Features And Outcomes Of Takotsubo (Stress) Cardiomyopathy In South Texas Hispanics, Cesar H. Gutierrez, Wady Aude

School of Medicine Publications

Background

Takotsubo cardiomyopathy (TSC) can be preceded by emotional, physical, or no identifiable trigger. Despite being a transient condition, it is associated with a substantial risk for in-hospital adverse events. The clinical features and the short-term outcomes of TSC in South Texas Hispanics (STH) are unknown.

Methods

We identified patients with the diagnosis of TSC at an academic institution from 2005-2017. Patients who did not have coronary angiography were excluded. Demographics, presenting symptoms, triggers, left ventricular characteristics and outcomes were expressed as percentages. Continuous variables were expressed as means.

Results

Of 41 patients with TSC, the diagnosis was confirmed in …

N Y State Dent J March 2020

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

An Appraisal Of Canine Transmissible Venereal Tumour With Emphasis On Molecular Biology And Pathology, Iniobong Chukwuebuka Ikenna Ugochukwu, Onyinyechukwu Ada Agina, Jacinta Ngozi Omeke, Chioma Inyang Aneke, Lawan Fatima Adamu, Olusola Lawrence Ajayi, Najume Dogowar Giginya Ibrahim, Celestine Ibe Njoku, Anthony Kojo Beku Sackey, John Ikechukwu Ihedioha

The Thai Journal of Veterinary Medicine

Canine transmissible venereal tumour (CTVT) is a contagious tumour of dogs, transmitted via coitus or coital behaviour which in some cases spreads by metastasis but primarily, CTVT appears as reddish soft nodules or papilla, protruding from the surface of the penis, prepuce, vagina and vulva but sometimes appears in locations outside the genitals. There was early evidence of CTVT more than 10,000 years ago and this disease has been reported in at least 90 countries across the continents of the world, especially in third world countries, where there are high numbers of stray dogs. CTVT natural infection occurs only in …