Medicine and Health Sciences Commons^™

2020-04-30_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-04-30_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

An Exploration Of Electrospun Fibers Containing Drug-Cyclodextrin Inclusion Complexes, Fatimah Fatimah, Zeynep Aytac, Tamer Uyar, George Pasparakis, Gareth R. Williams

Pharmaceutical Sciences and Research

A series of new core-shell fibers were developed containing anticancer drugs (5-fluorouracil or ferulic acid) and their cyclodextrin inclusion complexes, with a gadolinium-based magnetic resonance imaging (MRI) contrast agent. These were prepared by electrospinning, a simple method for producing ultra-fine fibers through the application of a strong electrostatic force on a polymer solution. The shell of the fibers was formed from Eudragit S100, and the drugs were loaded in the core. Scanning electron microscopy images showed the formation of smooth ribbon-like fibers, with diameters ranging from 1.4 to 5.1 μm, and transmission electron microscopy reveals a transparent interface between the …

Mouthguard Efficacy In Baseball Pitching Velocity, Nathan Iskowitz

Longwood Senior Theses

Successful pitching in baseball may be due to several factors including the mechanics of the motion, the strength, power, flexibility of the athlete, as well as their intent and fatigue levels. The pitching motion is a very powerful, violent, complex and abnormal range of motion of the body. In recent studies, it has been widely evidenced that the ability to produce instantaneous high peak force outputs is related to success in sport. Therefore, the ability to produce higher peak force may be related to the ability to pitching in baseball. Mouthguards have been shown to significantly increase power production in …

Effect Of Different Music Genres On Cognitive Task Performance After High Intensity Interval Training, Derek Jones

Longwood Senior Theses

The effects of high intensity exercise on cognitive performance are not fully understood. Music can affect physiological responses to exercise which may also impact cognitive performance. The aim of this study was to determine if music could impact cognitive performance after a bout of high intensity exercise. METHODS: Twelve subjects (n=7 males, n=5 females, 20.3 ± 1.7 y; 72.2 ± 14.9 kg; 1.70 ± 0.09 m) completed the Stroop test after a short (12 min) bout of high intensity interval exercise while listening to either Classical, Rock, or No Music. Subjects completed the Brunel Music Rating Inventory after listening to …

Precise Pregnancy Cohort: Challenges And Strategies In Setting Up A Biorepository In Sub-Saharan Africa, Rachel Craik, Donna Russell, Rachel M. Tribe, Marleen Temmerman, Angela Koech, Patricia Okiro, Geoffrey Omuse, Sikolia Wanyonyi

Obstetrics and Gynaecology, East Africa

Background and objective: PRECISE is a population-based, prospective pregnancy cohort study designed for deep phenotyping of pregnancies in women with placenta-related disorders, and in healthy controls. The PRECISE Network is recruiting ~ 10,000 pregnant women in three countries (The Gambia, Kenya, and Mozambique) representing sub-Saharan Africa. The principal aim is to improve our understanding of pre-eclampsia, fetal growth restriction and stillbirth. This involves the creation of a highly curated biorepository for state of the art discovery science and a rich database of antenatal variables and maternal and neonatal outcomes. Our overarching aim is to provide large sample numbers with …

Evaluating The Effectiveness Of Undergraduate Clinical Education Programs, John W. Ragsdale, Andrea Berry, Jennifer W. Gibson, Christiane R. Herber-Valdez, Lauren J. Germain, Deborah L. Engle

Medical Student Education Faculty Publications

Medical schools should use a variety of measures to evaluate the effectiveness of their clinical curricula. Both outcome measures and process measures should be included, and these can be organized according to the four-level training evaluation model developed by Donald Kirkpatrick. Managing evaluation data requires the institution to employ deliberate strategies to monitor signals in real-time and aggregate data so that informed decisions can be made. Future steps in program evaluation includes increased emphasis on patient outcomes and multi-source feedback, as well as better integration of existing data sources.

The Precise (Pregnancy Care Integrating Translational Science, Everywhere) Database: Open-Access Data Collection In Maternal And Newborn Health, Laura A. Magee, Amber Strang, Larry Li, Domena Tu, Warancha Tumtaweetikul, Rachel Craik, Marina Daniele, Angela Koech, Umberto D’Alessandro, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

In less-resourced settings, adverse pregnancy outcome rates are unacceptably high. To effect improvement, we need accurate epidemiological data about rates of death and morbidity, as well as social determinants of health and processes of care, and from each country (or region) to contextualise strategies. The PRECISE database is a unique core infrastructure of a generic, unified data collection platform. It is built on previous work in data harmonisation, outcome and data field standardisation, open-access software (District Health Information System 2 and the Baobab Laboratory Information Management System), and clinical research networks. The database contains globally-recommended indicators included in Health Management …

The Precise (Pregnancy Care Integrating Translational Science, Everywhere) Network’S First Protocol: Deep Phenotyping In Three Sub-Saharan African Countries, Peter Von Dadelszen, Meriel Flint-O’Kane, Lucilla Poston, Rachel Craik, Donna Russell, Rachel M. Tribe, Umberto D’Alessandro, Marleen Temmerman, Angela Koech, Anna Roca

Obstetrics and Gynaecology, East Africa

Background: The PRECISE (PREgnancy Care Integrating translational Science, Everywhere) Network is a new and broadly-based group of research scientists and health advocates based in the UK, Africa and North America.

Methods: This paper describes the protocol that underpins the clinical research activity of the Network, so that the investigators, and broader global health community, can have access to ‘deep phenotyping’ (social determinants of health, demographic and clinical parameters, placental biology and agnostic discovery biology) of women as they advance through pregnancy to the end of the puerperium, whether those pregnancies have normal outcomes or are complicated by one/more of the …

Harnessing The Precise Network As A Platform To Strengthen Global Capacity For Maternal And Child Health Research In Sub-Saharan Africa, Meriel Flint-O’Kane, Peter Von Dadelszen, Prestige Tatenda Makanga, Esperança Sevene, Anna Roca, Peter Dukes, Saba Hinrichs-Krapels, Rachel Craik, Laura A. Magee, Marleen Temmerman, Angela Koech, The Precise Network

Obstetrics and Gynaecology, East Africa

It is widely acknowledged across the global health sector that research programmes need to be designed and implemented in a way that maximise opportunities for strengthening local capacity. This paper examines how the United Kingdom Research and Innovation (UKRI) Grand Challenges Research Fund (GCRF) funded PRECISE (PREgnancy Care Integrating translational Science, Everywhere) Network has been established as a platform to strengthen global capacity for research focused on the improvement of maternal, fetal and newborn health in subSaharan Africa. Best practice principles outlined in an ESSENCE on Health Research report have been considered in relation to the PRECISE Network capacity-building activities …

Adapting The Asset Exercise For Humanitarian Contexts, Women's Refugee Commission, Population Council

Poverty, Gender, and Youth

As a guiding program theory, asset-building centers on the idea that skills, knowledge, relationships, and concrete resources can all constitute assets, or “stores of value,” that girls can, in turn, mobilize to make healthy choices, seek support, navigate institutions, and access entitlements. This approach is inherently multisectoral, rooted in a commitment to prioritize understanding of and respond to the diversity of girls’ needs, capacities, and experiences. The Asset Exercise operationalizes the concept of “asset-building” into concrete terms. The exercise consists of a deck of 100 “asset cards,” and eight “age cards.” Asset cards reflect both intrinsic qualities, concrete knowledge, and …

Value-Based Purchasing: Does Educating Direct Care Nurses Result In Value-Based Care?, Ryan Levi

Doctor of Nursing Practice Scholarly Projects

The United States health care system is undergoing the greatest transformation in the country’s history. Health care is rapidly moving away from volume-based reimbursement towards value-based models. The Hospital Value-Based Purchasing (VBP), a Center for Medicare and Medicaid pay-for-performance program, makes Medicare reimbursement contingent on performance in four quality categories. Clinical care, person and community engagement, safety, and efficiency determine an organization’s total performance score (TPS), which is used to impose positive, negative, or neutral payment adjustments. Nursing, more than any other health care profession, impacts hospitals’ TPS and subsequently Medicare reimbursement under VBP. While the literature indicates nurses should …

Policy Brief: Fertility Preferences And Behaviors Among Younger Cohorts In Egypt: Recent Trends, Correlates, And Prospects For Change [Arabic], Nahla G. Abdel-Tawab, Shadia Attia, Nourhan Bader, Rania Roushdy, Shatha El-Nakib, Doaa Oraby

Reproductive Health

After years of steady decline, Egypt experienced an increase in the total fertility rate (TFR) from 3.0 births per woman in 2008 to 3.5 in 2014, which was coupled with an increase in desired family size among young people. To better understand this increase in fertility as well as prospects for change, the Evidence Project/Population Council conducted secondary analyses of quantitative data from the Egypt Demographic and Health Survey (EDHS) and the Survey of Young People in Egypt (SYPE) and collected qualitative data from young people and key informants. This brief examines the changes in fertility preferences and behaviors among …

Fertility Preferences And Behaviors Among Younger Cohorts In Egypt: Recent Trends, Correlates, And Prospects For Change, Nahla G. Abdel-Tawab, Shadia Attia, Nourhan Bader, Rania Roushdy, Shatha El-Nakib, Doaa Oraby

Reproductive Health

After years of steady decline, Egypt experienced an increase in the total fertility rate (TFR) from 3.0 births per woman in 2008 to 3.5 in 2014, which was coupled with an increase in desired family size among young people. To better understand this increase in fertility as well as prospects for change, the Evidence Project/Population Council conducted secondary analyses of quantitative data from the Egypt Demographic and Health Survey (EDHS) and the Survey of Young People in Egypt (SYPE) and collected qualitative data from young people and key informants. This report examines the changes in fertility preferences and behaviors among …

A Model For The Spread Of Infectious Diseases In A Region, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher

Articles

In understanding the dynamics of the spread of an infectious disease, it is important to understand how a town’s place in a network of towns within a region will impact how the disease spreads to that town and from that town. In this article, we take a model for the spread of an infectious disease in a single town and scale it up to simulate a region containing multiple towns. The model is validated by looking at how adding additional towns and commuters influences the outbreak in a single town. We then look at how the centrality of a town …

Anticoagulation In Covid-19, Bassam Atallah

Faculty Scholarship

No abstract provided.

Geospatial Analysis Of Covid-19 And Otolaryngologists Above Age 60, Jeremy S. Ruthberg, Humzah A. Quereshy, Tarun K. Jella, Brian D'Anza, Nicole Maronian, Todd D. Otteson

Faculty Scholarship

Objective: The 2019 novel coronavirus (COVID-19) is disproportionately impacting older individuals and healthcare workers. Otolaryngologists are especially susceptible with the elevated risk of aerosolization and corresponding high viral loads. This study utilizes a geospatial analysis to illustrate the comparative risks of older otolaryngologists across the United States during the COVID-19 pandemic. Methods and materials: Demographic and state population data were extracted from the State Physician Workforce Reports published by the AAMC for the year 2018. A geospatial heat map of the United States was then constructed to illustrate the location of COVID-19 confirmed case counts and the distributions of ENTs …

2020-04-30 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

2020-04-30 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Lori D. Sloane, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Emma Wolinsky, Fiona Nguyen, Ryen Ormesher, Melissa Cossé, Lauren Tagliaferro Epler, Timothy Campbell, Aly Raboff, Hannah Dowdy-Sue, John Powell, Ariel Hurwitz, Alexandra Yingling, Perez Olewe, Gregory Mertz, Kristine Tollestrup, Orrin Myers, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

NM residential facility deaths. NM case update. NM TriCore testing antibodies. Navajo nation cases. May 10 Navajo peak. Udall funding push. El Paso shopping discouraged. NM budget shortfall. Santa Fe furlough. Ethanol sanitizer safety. LA free testing for all. Michigan protest. NM Batelle N95 decontamination. Hospital revenue decline. Wastewater early detection. German herd immunity. 60-day viral shedding possible. Temporary infected “ark”. Prison release preparedness. Low quality research. Phased long-term care. Suicide prevention. Corticosteroid tradeoffs. Cloth mask guidelines. SARS-CoV-2 assays compared. IgG and viral loads. Better testing reporting. Dubious testing vendors. Promising oral drug. Hydroxychloroquine prophylaxis dosing. Umifenovir ineffective. …

Mindfulness And Testing: An Exploration Of The Benefits Of Mindfulness Based Cognitive Meditation Practice On Test Anxiety, Anastasia Quirk

Graduate Theses, Dissertations, and Capstones

Test anxiety is a growing concern for students as it can negatively impact student performance. Mindfulness is a practice of focused breathing meditation intended to increase awareness of oneself and the present moment and decrease anxiety. With the recent increase in mindfulness practices in schools, this research examines the potential impact of mindfulness-based cognitive practice on anxiety levels, test anxiety, and standardized test scores through the use of the ACT standardized placement test, the TAI-G, a self-administered Test Anxiety Inventory, and the Biodot, a device measuring physiological indications of anxiety. Using analysis of variance and paired samples t-tests, a significant …

Development Of Drive-Through And Mail-In Systems For Obtaining Surveillance Respiratory Specimens In A Pediatric Cystic Fibrosis Center, Ellen Meier, Paula Capel, Christopher M. Oermann

Posters

Routine surveillance cultures are an essential part of health maintenance for people with cystic fibrosis (CF). The Cystic Fibrosis Foundations (CFF) recommends that respiratory cultures be obtained every three months. The CF Care Center at Children’s Mercy Kansas City (CMKC) also obtains respiratory cultures when there is an acute change in respiratory symptoms. The COVID-29 pandemic resulted in ambulatory clinic closures and an inability to obtain surveillance respiratory cultures. A creative solution for obtaining respiratory cultures was needed during the pandemic.

The Contribution Of Qualitative Research Within The Precise Study In Sub-Saharan Africa, Marina A. S. Daniele, Melisa Martinez-Alvarez, Angela Koech, Marianne Vidler, Tatiana Salisbury, Prestige Tatenda Makanga, Peris Musitia, Meriel Flint-O’Kane, Tanya Wells Brown, Brahima Amara Diallo, Marleen Temmerman, Geoffrey Omuse, Sikolia Wanyonyi, Patricia Okiro

Obstetrics and Gynaecology, East Africa

The PRECISE Network is a cohort study established to investigate hypertension, fetal growth restriction and stillbirth (described as “placental disorders”) in Kenya, Mozambique and The Gambia. Several pregnancy or birth cohorts have been set up in low- and middle-income countries, focussed on maternal and child health. Qualitative research methods are sometimes used alongside quantitative data collection from these cohorts. Researchers affiliated with PRECISE are also planning to use qualitative methods, from the perspective of multiple subject areas. This paper provides an overview of the different ways in which qualitative research methods can contribute to achieving PRECISE’s objectives, and discusses the …

Designing An Antibiotic Eluting Trauma Screw To Reduce Short Term Infection In Bone Fractures, Dominic Lincoln

Honors Theses

Orthopedic infection in the United States is one of the most common and severe health risks faced by trauma patients. The most prevalent infection is orthopedic and trauma device-related infection (ORDI) and often occurs in long bones at the fracture site. The purpose of this paper is to explore this infection, its causes, and solutions currently on the market while providing novel solutions to the problem. The designs proposed will be evaluated for their effectiveness and value, while attempting to keep costs low for all stakeholders. The feasibility of patenting these ideas will also be considered, as will the testing …

Determining Age-Related Visual Memory And Line Length Perception In Children And Adults, Katie Exline

Undergraduate Honors Thesis Projects

There is little research in the field of visual memory and perceptual abilities of children as compared to adults. This thesis seeks to understand and provide new perspectives to this field with potential implications in the fields of optometry and education. Through two basic experiments, this thesis evaluates the abilities of individuals to perceive a visual stimulus and compare it other visual stimuli, while also observing their abilities to learn and remember various visual stimuli. Through experimentation using line length as the visual stimulus, the method of constant stimuli (MCS) evaluates subjects’ visual perception and the method of single stimuli …

Development Of Ethanolic Extract Of Pinang Masak Jambi (Areca Catechu L.) As A Modulator Of Doxorubicin Cytotoxic Effect In Breast Cancer Therapy, Fitrianingsih Fitrianingsih, Indri Maharini, Diah Tri Utami

Pharmaceutical Sciences and Research

Doxorubicin is one of the chemotherapy agents that is often used in breast cancer therapy. Phenomenon of breast cancer cell resistance to chemotherapy agents has been traced to the molecular level. The development of compounds that can overcome drug resistance chemotherapy needs to be continuously developed, especially agents with specific molecular targets, namely P-glycoprotein (Pgp), NFkB, cyclin, and cyclin-dependent kinase (CDK). Another alternative is the combination of chemotherapy agents with chemopreventive agents (co-chemotherapy) to reduce side effects and increase sensitivity of cancer cells. Doxorubicin is often used in breast cancer therapy. This study was performed to determine the effect of …

Anti-Proliferative Effects Of A Coumarin Benjaminin On Four Human Cancer Cell Lines, Siau Hui Mah, Soek Sin Teh, Ahmad Azri Fitri Ismail, Gwendoline Cheng Lian Ee

Pharmaceutical Sciences and Research

Cancer is a major health issue around the globe. Chemotherapy and radiation therapy are no longer the standard treatments for patients as these remedies lead to many adverse effects. Thus, the development of alternative effective drugs from lead compounds, especially natural products is necessary. This study aimed to isolate cytotoxic phytochemical constituents from a plant Calophyllum inophyllum, which has been used as traditional medicine since ancient time. The root of C. inophyllum was extracted and subjected for phytochemical constituent isolation. A coumarin, benjaminin (1) was isolated successfully from the chloroform extract and its structural elucidation was performed by spectroscopy analyses …

Ace Inhibitory Activity And Functional Group Analysis Of Solvent- Partitioned Fractions Of Eleusine Indica, Jade Celon Cometa, Liahona Faith Roldan Mancol, Anthony Nalzaro Yen, Joanne Katherine Talens Manlusoc

Pharmaceutical Sciences and Research

Eleusine indica Linn. Gaerth or Indian goose grass has been widely used as an alternative natural anti-hypertensive agent. However, the rationale behind this mechanism is still unknown. The purpose of this study is to confirm the presence of functional groups that may be responsible for its ACE inhibitory activity and its possible synergism. Each solvent-portioned fraction was analyzed by FTIR, individual ACE inhibitory activity, and combination of fractions. FTIR results of solvent- partitioned fractions revealed that O-H and C-H stretches were present in all fractions. In addition to this, C-O and C=O groups were also present in all fractions except …

Brain Injury And Dementia In Pakistan: Current Perspectives, Maheen M. Adamson, Sadia Shakil, Tajwar Sultana, Muhammad Abul Hasan, Fatima Mubarak, Ather Enam, Muhammad A. Parvaz, Adeel Razi

Department of Radiology

Alzheimer's disease (AD) is the most common form of dementia, accounting for 50-75% of all cases, with a greater proportion of individuals affected at older age range. A single moderate or severe traumatic brain injury (TBI) is associated with accelerated aging and increased risk for dementia. The fastest growth in the elderly population is taking place in China, Pakistan, and their south Asian neighbors. Current clinical assessments are based on data collected from Caucasian populations from wealthy backgrounds giving rise to a "diversity" crisis in brain research. Pakistan is a lower-middle income country (LMIC) with an estimated one million people …

Nicaragua's Response To Covid-19 – Authors' Reply, Mateo Jarquin, Andrea M. Prado, Benjamin Gallo Marin

History Faculty Articles and Research

An author's to John Perry's commentary ("Nicaragua's Response to COVID-19"), which was itself written in response to Mather, Gallo Marin, Medina Perez, et al.'s "Love in the Time of COVID-19: Negligence in the Nicaraguan Response".

Original article: Salazar Mather TP, Gallo Marin B, Medina Perez G, et al. Love in the time of COVID-19: negligence in the Nicaraguan response. The Lancet Global Health. 2020;8(6):e773. doi:10.1016/S2214-109X(20)30131-5 Perry's commentary: Perry J. Nicaragua’s response to COVID-19. The Lancet Global Health. Published online April 2020. doi:10.1016/S2214-109X(20)30218-7

One-Year Progress Oa A Large-Scale Collaborative Project For Improving The Care Of Mechanically Ventilated Patients, Yaseen M. Arabi, Zohair Al Aseri, Tareef Alaama, Abdulrhman Alharthy, Fahad M. Al-Hameed, Yasser Mandourah, Alyaa Elhazmi, Hend Sallam, Ghaleb A. Almekhlafi, Asad Latif

Department of Anaesthesia

No abstract provided.