Medicine and Health Sciences Commons^™

Concordance Between Electronic Health Record Data And Medicare Part D Claims Data For Oral Anticancer Drug Use, Manvi Sharma, Michael L. Johnson, Hui Zhao, Sharon H. Giordano, Holly M. Holmes

Faculty and Student Publications

Real-world evidence from electronic health records (EHRs) and claims data are being evaluated for use in regulatory decision-making.^1,2 The objective of our study was to determine the concordance between EHR and Medicare Part D (MPD) claims data for the receipt of oral anticancer agents, a rapidly growing treatment option for cancer.

Robotic Adrenalectomy For Functional Adenoma In Second Trimester Treats Worsening Hypertension., Courtney E. Capella, Thenappan Chandrasekar, May Jean Counsilman, Christopher Sebastiano, Costas D. Lallas, Huda B. Al-Kouatly

Department of Urology Faculty Papers

A 33-year-old G6P3023 was found to have a 4.2 cm right adrenal incidentaloma during an admission for right pyelonephritis. Computed tomography (CT) was performed to rule out perinephric abscess in the setting of worsening leukocytosis while on antibiotics ( Fig. 1). Initial differential diagnosis from endocrinology included pheochromocytoma and primary aldosteronism. Due to the lack of typical physical exam stigmata, Cushing syndrome was initially of low concern. Of note, her past medical history included hypertension treated with amlodipine 10 mg and hydrochlorothiazide 12.5 mg. During admission, extensive endocrine laboratory workup demonstrated an elevated aldosterone:plasma renin activity, suppressed dehydroepiandrosterone (DHEA), normal …

Reasons For Facebook Usage: Data From 46 Countries, Marta Kowal, Piotr Sorokowski, Agnieszka Sorokowska, Małgorzata Dobrowolska, Katarzyna Pisanski, Anna Oleszkiewicz, Toivo Aavik, Grace Akello, Charlotte Alm, Rizwana Shaikh

Department of Paediatrics and Child Health

No abstract provided.

Evaluation Of Potential Drug Interaction Of Analgesic In Cancer Patient Receiving Palliative Care In Dharmais Cancer Hospital, Eme Stepani Sitepu, Atika Wahyu Puspitasari, Nuriza Ulul Azmi, Lila Nilam Sari

Pharmaceutical Sciences and Research

Analgesics are mostly used in cancer patients receiving palliative care to improve the quality of life of patients. Besides analgesics, cancer patients receiving palliative care were also given other drugs in combination to overcome other symptoms of cancer, and this combination could potentially cause drug interactions. This study was aimed to analyze the potential of drug interactions with analgesics in cancer patients. The study design was cross-sectional with a retrospective method and descriptive study. The sample of this study was cancer palliative care patient’s prescription at Dharmais Cancer Hospital in the period of January – December 2017. The sample analyzed …

Formulasi Gel Ekstrak Daun Kelor (Moringa Oleifera Lamk) Sebagai Sediaan Antiinflamasi, Nining Sugihartini, Syauqul Jannah, Tedjo Yuwono

Pharmaceutical Sciences and Research

The development of anti-inflammatory gel of Moringa oleifera leaf extract has been performed. This study aimed to determine the physical properties, irritation index and anti-inflammatory activity of gel with various concentration of Moringa oleifera leaf extract. The extract was obtained by maceration method using ethanol 70%. The extracts were formulated in a gel with a concentration of 3%, 6%, 9% by using Carbopol 940 as gelling agent. The gel was evaluated for its physical properties (viscosity, pH, spreadability, adhesivity), irritation index with rabbit test animals and anti-inflammatory activity with mice test animals based on epidermal thickness parameters. The test results …

Profil Terapi Antihipertensi Dan Antihiperlipidemia Terhadap Fungsi Ginjal Pasien Diabetes Melitus Tipe 2 Dengan Komplikasi Penyakit Ginjal Kronis Di Rsup Dr. Hasan Sadikin, Fitri Rachmaini, Lia Amalia, Cherry Rahayu

Pharmaceutical Sciences and Research

Chronic Kidney Disease (CKD) complication increases the risk of morbidity and mortality in type 2 diabetes mellitus (DMT2) patients. The presence of hypertension and dyslipidemia as comorbidity increases the risk of macrovascular and microvascular complications and further adding to the list of drugs used. Management of this comorbidity is essential to prevent cardiovascular events and minimize kidney damage. This study aimed to evaluate therapeutic profile of antihypertensive and antihyperlipidemia drugs towards kidney function in DMT2 patients with CKD complication at Dr. Hasan Sadikin Hospital. Study was done by using a prospective single cohort design with consecutive sampling technique and obtained …

Interaction Of Thymidine With Sodium Bis(2-Ethylhexyl) Sulfosuccinate In Alcohol And Water: Studies With Uv-Vis Technique, Indu M. Paudel, Ajaya Bhattarai

Pharmaceutical Sciences and Research

The accurate measurement of thymidine absorbance in the presence of sodium bis(2-ethylhexyl) sulfosuccinate (AOT) in ethanol and water systems at room temperature by UV-vis technique has been reported. The AOT concentrations varied from 0.0005 to 0.014 [mol/L] in ethanol whereas from 0.0002 to 0.042 [mol/L] in water. The concentration of thymidine was 0.0073 [mol/L] during UV-vis spectrum registration. The thymidine spectrum was examined in the presence of AOT concentration. Using a statistical method of non-linear regression (NLREG), thymidine binding and thymidine distribution constants were evaluated. A noticeable decrease in thymidine absorbance in the presence of AOT concentration was shown in …

Assessment Of Depression Among Older Adults Staying In Old Home Care In Klang, Malaysia, Muhammad Qamar, Nurul Zahirah, Sohail Ahmad

Pharmaceutical Sciences and Research

Mental disorders such as depression are widespread, often underdiagnosed, and usually inappropriately treated. The early recognition of factors that may promote depression with the help of depression screening aid can help to plan better care for the patient. Therefore, this study aimed to determine the depression prevalence among the older adults staying in old home care, to explore any association and differences of depression across various socio-demographic variables, and to study the predictors of depression among study subjects. A cross-sectional study was conducted with a convenience sample of 141 elderly by using the validated tool. The study instrument was divided …

Encapsulation Of Temulawak Extract By Using Nanocrystalline Cassava And Sago Starches And Maltodextrin, Titi Candra Sunarti, Fatimah J. Pasaribu, Christina Winarti

Pharmaceutical Sciences and Research

This study was conducted to evaluate the performance of Curcuma zanthorrhiza crude extract after encapsulated in nanocrystalline starch, and to investigate the effect of the ratio of nanocrystalline starches and maltodextrin; and the effect of concentration of temulawak extract on nanocapsule characteristics, as well as encapsulation effect on the stability of antioxidant activity. Preparation of nanocrystalline starch was conducted by using lintnerization and ethanol precipitation of cassava and sago starches. Nanocrystalline starch and maltodextrin were used as matrices with the ratio varied from 25:75, 50:50, and 75:25. The mixture of temulawak extract and matrices were homogenized and spray dried. Nanocapsules …

2020-04-29 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Lectin Properties Of Synthetically Produced Glucuronate, Alginate, And Related Boronates, Vanessa Angel

Honors Theses

In the nineteenth century, researchers discovered that some proteins had the ability to agglutinate red blood cells (Goldstein, 1980). These proteins were found mainly in the seeds of leguminous plants and were named phytohemagglutinins or hemagglutinins. Particular hemagglutinins were able to agglutinate red blood cells (RBCs) of a specific blood type. Now a days, these proteins are more widely known as Lectins. Lectins are proteinaceous macromolecules of nonimmune origin, capable of interacting with carbohydrates to form complexes (Goldstein, 1980). Lectins sources derive mainly from leguminous plants, animals, fruiting bodies of fungi, and bacteria. This research focuses on identifying the lectin …

Incorporating A Clinical Pharmacist In An Outpatient Palliative Care Team, Crystal Rim, Sharon Leigh, Linda Desitter, Mary Grant, Dana Nguyen

Providence Pharmacy PGY1 Program at Providence Milwaukie and Providence Newberg Medical Centers 2020

Title: Incorporating a clinical pharmacist in an outpatient palliative care team

Crystal Rim, PharmD; Sharon Leigh, PharmD, BCPS; Linda De Sitter MD, MPH; Mary Grant, ANP; Dana Nguyen, PharmD

Palliative care is a growing field in medicine that focuses on delivering care that improves quality of life for patients with serious illnesses. Often, the goals of palliative care differ from traditional goals of medicine. Currently, there is limited data demonstrating the integration of pharmacists in the palliative care setting. The purpose of this quality improvement is to evaluate the clinical pharmacist’s role within an outpatient palliative care team when performing …

Impact Of Academic Detailing On Clinical Pharmacy Specialist Involvement In Medication Assisted, Lindsey M. Bartos, Kristin A. Tallman, Dara L. Johnson

Providence Pharmacy PGY2 Program at Providence Medical Group 2020

Title: Impact of academic detailing on clinical pharmacy specialist involvement in medication assisted treatment for opioid use disorder in a primary care setting

Lindsey Bartos, PharmD; Kristin Tallman, PharmD, BCPS, BCACP; Dara Johnson, PharmD, BCPP, BCACP

Introduction: Opioid prescribing and opioid overdose deaths have increased steadily since the 1990s, reaching a 6-fold increase between 1999 and 2017. The opioid crisis, as it became known, was declared a public health emergency in 2017. In 2018 alone, an estimated two million people had a diagnosed opioid use disorder (OUD). The use of medication-assisted treatment (MAT) for OUD reduces the use …

Some Of My Journal Entries During Covid-19, Brooke Studnicki

Reflections, Poetry, Photos, and other Writings

These are some journal entries that I was looking back on while we were sent home in quarantine. They began during the period of time when the coronavirus first seemed to effect my life. I believe they are able to show some of the ways God was working amidst the uncertainty.

Publicly Available Machine Learning Models For Identifying Opioid Misuse From The Clinical Notes Of Hospitalized Patients, Brihat Sharma, Dmitriy Dligach, Kristin Swope, Elizabeth Salisbury-Afshar, Niranjan S. Karnik, Cara Joyce, Majid Afshar

Biostatistics Collaborative Core: Faculty Publications and Other Works

Background: Automated de-identification methods for removing protected health information (PHI) from the source notes of the electronic health record (EHR) rely on building systems to recognize mentions of PHI in text, but they remain inadequate at ensuring perfect PHI removal. As an alternative to relying on de-identification systems, we propose the following solutions: (1) Mapping the corpus of documents to standardized medical vocabulary (concept unique identifier [CUI] codes mapped from the Unified Medical Language System) thus eliminating PHI as inputs to a machine learning model; and (2) training character-based machine learning models that obviate the need for a dictionary containing …

2020-04-29_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Available Bed Tracking for COVID-19, COVID-19 Metrics, Statewide Available PPE Tracking for COVID-19 (Statewide Available PPE and Bed Tracking), as well as the tables PPE Days On Hand and Patient Census.

2020-04-29_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was captured from the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_99207---,00.html.

The website contained the table Count of Confirmed COVID-19 Cases by Date of Onset , sorted by Michigan Preparedness Region. It also contained 18 charts, including the count of confirmed Covid-19 cases by date of onset in the state overall as well as in each preparedness region,and the normalized rate of Covid-19 cases per 1,000,000 residents in both the state and in each preparedness region.

2020-04-29_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Ua94/6/1 My Story: Track & Field's Dedrick Troxell, Dedrick Troxell

Student/Alumni Personal Papers

My Story is a series of first-person feature articles written by WKU student-athletes. The student-athletes will be telling their own stories in their own words. This article written by cross county sophomore Dedrick Troxell, who had just wrapped up a great indoor season and was primed for a dominant outdoor campaign.

Impact Of Pharmacist-Led Appointments For Hypertension Management In A Primary Care Setting: A Retrospective Analysis, Anne Marie Thibodeaux, Christine Doran, Ben Rosati

Providence Pharmacy PGY2 Program at Providence Medical Group 2020

Impact of pharmacist-led appointments for hypertension management in a primary care setting: a retrospective analysis

Introduction: High blood pressure is a major risk factor for heart disease and stroke, two of the leading causes of death for Americans.1 Evidence supports the idea that pharmacist-led hypertension management can result in overall blood pressure reduction; however, it remains unclear whether pharmacist-led initiatives can also improve performance metrics.2-5

Research question: Can pharmacist-led appointments for blood pressure management positively impact hypertension metrics?

Study design: Retrospective chart review

Methods: Primary outcome data was measured via metric inventory, defined as percentage of …

2020-04-29_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

Consumer Assessment Of Healthcare Providers And Systems In A Psychiatry Practice, Treacy Williams

Dissertations

Problem: Patient-centered care improves healthcare. Patient surveys are instruments used to assess the patient’s experience and is essential to providing patient-centered care. The aim of this quality improvement initiative was to assess patient perceptions of care delivered by nurse practitioner (NP) providers in a psychiatric mental health practice.

Methods: An observational, descriptive design with a customized Consumer Assessment of Health Care Providers and Systems (CAHPS) survey administered in an outpatient psychiatric mental health practice for six weeks. A structure, process, outcomes framework was used. The structure of study was care delivered by the NP, the process of interest was communication …

2020-04-29 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Susan Atlas, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Alexandra Yingling, Melissa Cosse, Lauren Tagliaferro Epler, Allison Price, Fiona Nguyen, Ariel Hurwitz, Jenny Situ, Ryen Ormesher, Timothy Campbell, Perez Olewe, Clinton Onyango, Kristine Tollestrup, Cristian Bologa, Jens Langsjoen, Gregory Mertz, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

NM cases. NM coronavirus origins. Governor update tomorrow. Temporary drivers licenses. Negative tracing app sentiment. CA reopening plans. US travel screening. Influenza reductions w/COVID control. German flu vaccine prep. 1.5B jobs at risk. National health expenditures. US economy shrinks. Aerosolized virus in hospitals. Cellphone disease spread prediction. Social distancing study. Isolation policy effectiveness. Contact tracing to end AIDS/HIV. Homeless shelter prevalence. Predicting herd immunity. Cooler temperatures reduce transmission. NEJM rationing rationalization. ECMO regional planning. Canadian ECMO prioritization. Healthcare worker mental health. Infectious Diseases Society guidelines. US hospitalist guide. Managing pregnancies. Coagulopathy management. Hysteroscopy consensus. Renal transplant immunosuppression. Two …

Has Covid-19 Impacted Price-Weight Relationships And Value Of Gain?, Elliott James Dennis

Extension Farm and Ranch Management News

First paragraph:

In the beginning of COVID-19, much of the attention was focused on managing the redirection of meat product from food service to retail stores. This past month has keenly focused on packing plant closures due to COVID-19 cases among workers and how to manage the supply of fat cattle already ready for slaughter. Fat cattle available for slaughter either cannot get bids or bids are significantly below breakeven prices leaving feedlots with decisions to be made about marketing and placements. The April 2020 Cattle on Feed report (https://usda.library.cornell.edu/concern/publications/m326m174z) revealed March placement decisions. Placements were down about …

A Proposal To Implement Assertive Community Treatment Into A Primary Care Shelter Clinic, Julie Churcher-Fields

Theses and Graduate Projects

Individuals who are experiencing homelessness and severe mental illness have a difficult time accessing healthcare systems. Without mental health treatment and stable housing, individuals develop multiple needs that must be addressed during an individual visit. Without treatment for mental health symptoms, individuals may experience a negative impact on their quality of life and the ability to get basic needs met. Community organizations have an obligation to provide integrated care with a goal to improve overall health for this population. As nurse leaders there is an opportunity to be advocates and implement innovative ideas to improve care. In a large adult …

Evaluation Of Transitional Care Interventions From A Decentralized Clinical Pharmacist In A Small Inpatient Geriatric Psychiatry Unit, Nathan Wong, Michael Brown

Providence Pharmacy PGY1 Program at Providence Milwaukie and Providence Newberg Medical Centers 2020

Evaluation of Transitional Care Interventions from a Decentralized Clinical Pharmacist in a Small Inpatient Geriatric Psychiatry Unit

Nathan Wong, PharmD; Michael Brown, RPh, BCPS, BCPP

Background: Transitioning between healthcare settings increases the risk for medication errors. A systematic review of 26 studies comparing various medication reconciliation interventions demonstrated consistent reductions in adverse drug events. Intensive pharmacist involvement and focus on high risk populations were the most successful. ¹ Geriatric and behavioral health populations are especially vulnerable with polypharmacy and cognitive impairment often complicating the picture. Providence Milwaukie Hospital (PMH) houses a small unit tailored to provide mental health care …

Empowering Caregivers To Recognize, Support, And Treat Opioid Use Disorder: An Interdisciplinary Assessment Of Knowledge, Attitudes, And Comfort Level Pre And Post-Education, Annette Sprankle, Mika Michaels

Providence Pharmacy PGY1 Program at Providence Medford 2020

Author: Annette Sprankle, PGY1 Pharmacy Resident, PMMC

Title: Empowering caregivers to recognize, support, and treat opioid use disorder: an interdisciplinary assessment of knowledge, attitudes, and comfort level pre and post-education

Background: Substance use disorder affects approximately one in every four hospitalized patients. These patients are often treated for the admitting medical issue without addressing their substance use disorder. A hospital admission provides an opportunity to connect patients to the medical system. Evidence demonstrates that starting medication-assisted treatment in the hospital reduces the risk of overdose upon discharge, rate of hospital readmission, length of stay, and hospital expenditures.

Purpose: The purpose …

A Marker Of Systemic Inflammation Or Direct Cardiac Injury: Should Cardiac Troponin Levels Be Monitored In Covid-19 Patients?, Bassam Atallah

Faculty Scholarship

No abstract provided.

Project Nurture: An Educational Model For Substance Use Disorder Treatment During & After Pregnancy: Saving Lives, Saving Money, Saving Families, And Training Future Doctors, Roxanne Thomas, Brenda Brischetto, Josh Reagan, Daniel Ruegg

Milwaukie Family Medicine 2020

BACKGROUND: • 25% of women presenting for prenatal care are using substances. • Substance Use Disorders (SUDs) in pregnancy are associated with preterm birth, intrauterine growth restriction, placental abruption, increased risk of C-section. • Infants exposed to in utero illicit substances have higher likelihood of being small for gestational age, experiencing a neonatal opioid withdrawal syndrome that requires prolonged NICU hospitalization, and are at higher risk of developmental delay. • Societal costs of SUDs in pregnancy include worsening mental illness, increased utilization of the foster care system, early death secondary to overdose, and associated financial burdens. • The nature of …

Quality Improvement: Improving Depression Screening Rates At Pmg Southeast Family Medicine Clinic, Elizabeth Deyo, Edward Kim, Tyler Nelson, Roxanne Thomas, Jemie Walrod, Nicholas Wolfgang, Ben Pederson

Milwaukie Family Medicine 2020

Introduction: Major depressive disorder is one of the most common mental health problems encountered by primary care providers in the U.S. For people age 12 and older, prevalence is estimated at eight percent. The economic cost of depression has been estimated at $210.5 billion per year, attributed to both costs to the work place and medical costs. People who experience depression are at greater risk for suicide, an otherwise preventable death if depression can be recognized and adequately treated. For these reasons, depression screening has become an essential function within primary care practices both within Providence and nation-wide.