Comparison In The Effectiveness Of Mat In Patients With Oxycodone Vs Heroin Opioid Use Disorders, Casey Myklebust

Physician Assistant Scholarly Project Papers

The purpose of this research and systematic literature review is to determine if there is a measurable difference of effectiveness in medication assisted treatment (MAT) in patients with oxycodone and heroin use disorders, retention in treatment, and sustained sobriety. In this review, the databases searched included CINAHL, Clinical Key, and Embase. A variety of key terms and MeSH terms were used to define a set of literature discussing the topic. The works chosen for review were published between 2015 and 2019 were peer reviewed, and included randomized control trials, pilot studies, and systematic reviews. Sources that were excluded, included those …

Catheter Ablation Of The Accessory Pathway In The Asymptomatic Patient With Wolff-Parkinson-White, Erin Breann Mondry

Physician Assistant Scholarly Project Papers

Wolff-Parkinson-White (WPW) is a condition in which an accessory conduction pathway exists within the heart. This accessory pathway may or may not cause symptoms, in fact, the first manifestation of the condition may be sudden cardiac death. The management of this condition in asymptomatic individuals is controversial. The purpose of this research and literature review is to analyze the safety and efficacy associated with invasive catheter ablation of the accessory pathway, in comparison to risk of sudden cardiac death and malignant arrythmias in non-ablated, asymptomatic individuals with WPW. In this review, five databases were searched including CINAHL, Clinical Key, PubMed, …

The Safety, Accuracy, And Cost-Effectiveness Of Confirmatory Penicillin Allergy Testing In The Outpatient Setting As A Means Of Reducing Patient Morbidity And Mortality, Mitchell Mimbach

Physician Assistant Scholarly Project Papers

The purpose of this review is to investigate the prevalence of documented penicillin (PCN) allergies in health care and any negative outcomes associated with being labeled as such. Additional topics researched included the safety and accuracy of PCN allergy testing, the cost-effectiveness of PCN allergy testing versus using non-PCN related antibiotics, and barriers to confirmatory PCN allergy testing implementation. A complete review of the aforementioned topics included meta-analysis’, systematic reviews, cohorts, clinical trials, and cross-sectional studies from the last five years. Databases utilized for this research included PubMed, Cochrane Review, Embase, Dynamed Plus, and ClinicalKey. Sources that were excluded from …

An Analysis Of The Incidence And Severity Of Drug-Drug Interactions Between Prescribed Pharmaceuticals And Cannabinoids, Jennifer Lee Mcrae

Physician Assistant Scholarly Project Papers

The purpose of this research and systematic literature review is to identify the incidence and severity of drug-drug interactions between commonly prescribed medications and cannabinoids. In this review, four databases were searched including PubMed, CINAHL, and Embase from October 1 to January 5, 2019. A variety of key terms were used when searching. Works chosen for review were published after the year 2014, were peer reviewed, and included randomized control trials (RCTs), systematic literature reviews, and meta-analyses. For this review, 9 resources were selected. Much of the research presented shows evidence that medications that are substrates for CYP2C19, CYP2C9 and …

Evaluation Of Hyperbaric Oxygen Therapy In The Treatment Of Traumatic Brain Injuries, Jordan Wiedmann

Physician Assistant Scholarly Project Papers

Traumatic brain injuries (TBIs) affect approximately 2.5 million people each year (Brain, 2014). The most current treatment options for TBIs include extensive long-term rehabilitation and therapy services, in which many only gain little improvement of their overall health (Traumatic, 2019). New trends in treating TBIs with hyperbaric oxygen therapy (HBOT) are emerging due to increased accessibility to hyperbaric oxygen chambers. The purpose of this research and systematic literature review is to evaluate the safety and efficacy of using HBOT to improve the treatment outcomes of TBIs. This review included the search of four databases including PubMed, Cochrane Review, Clinical Key, …

Treatment Option Decision Making For Low-Grade Prostate Cancer, Janene Caldwell Witherite

Physician Assistant Scholarly Project Papers

Prostate cancer (PCa) is the second most common cancer, behind skin cancer, among men, in the United States (Centers for Disease Control and Prevention [CDC], 2019.). PCa is defined as low-grade or low risk if the neoplasm grows slowly or not at all. According to the Institute for Quality and Efficiency in Health Care, (2020), to make the conclusion that a PCa is low-grade, several tests are performed including a prostate specific antigen (PSA) level, a Gleason score, and a TNM score, which refers to tumor size, lymph node involvement, and metastasis outside the prostate. Low-grade PCa is further defined …

Analysis Of Tech-Based And Telemental Health Approaches Within The Adolescent And Young Adult Populations Of Rural America, Audrey Smeenk

Physician Assistant Scholarly Project Papers

Background: The incidences of depression and anxiety among adolescent and young adult populations are intensifying, and resources remain limited for the management of these diseases within rural America. Objective: The purpose of this literature review is to evaluate evidence-based practices regarding telemedicine and tech-based mental health interventions. Evaluation of different interventions will demonstrate the ability of access, efficacy, and patient adherence with the hope of decreasing the incidence of disease and increase the availability of resources to rural areas. Methods: A comprehensive literature review was completed by assessing journal articles and scientific databases from the last fifteen years using a …

Low-Dose Naltrexone For Treatment In Crohn’S Disease And Fibromyalgia, Hannah Rachel Tkach

Physician Assistant Scholarly Project Papers

The United States has experienced a dramatic increase in opioid abuse and overdoses, leading to a national epidemic. Contributing to this epidemic is the use of opioid therapy for complex chronic inflammatory and neuropathic conditions that remain difficult to treat. Many traditional treatments are ineffective or have intolerable side effects, forcing providers to utilize opioid therapy as a last resort. Recently, there is increased interest in the use of partial opioid antagonist naltrexone to treat Crohn’s disease and fibromyalgia. Previous research suggests the potential for naltrexone to provide analgesic effects when administered in low doses via its unique interaction with …

Resting Heart Rate And Its Effect On Cardiovascular Disease, Peter Tronset

Physician Assistant Scholarly Project Papers

The purpose of the presented research and systematic review is to determine the associated impact resting heart rate has on development of cardiovascular disease. A literature review was conducted through electronic databases: PubMed, Clinical Key and Dynamed Plus. No limitation of timeframe was used when researching as few studies are available correlating resting heart rate and its associated development of cardiovascular disease. Research points to limitations of lowering resting heart rate due to adverse effects on blood pressure. Additionally, tachycardia is addressed through several methods including lifestyle modification and pharmacologic therapy. Comorbidities such as obesity, low body mass index (BMI), …

Relationships For Social Change: A Longitudinal Examination Of A Promotora-Led Program For Socioeconomic Mobility, Dayanne Assunção Vieira Carter

Loma Linda University Electronic Theses, Dissertations & Projects

Since the 1960s federal and local initiatives have been put in place to decrease the staggering socioeconomic disparities in the United States. Considerable debate has been fueled by the conception of adequate solutions to address the employment crisis (Kregel, 2011). Despite the increase in supportive services made available to the public, low-income families continue to face distinct challenges that limit employment and vocational opportunities (Athreya & Romero, 2015; Crouter & Booth, 2014; Presser, 2014), a situation particularly true for ethnic minorities navigating the systems of employment in the US (Fullerton & Anderson 2013; Mazumder, 2011). The purpose of this study …

Comparison Of Heat Generated During Twist Drilling Protocol By Guided And Non-Guided Implant Surgery, Joshua Lee

Loma Linda University Electronic Theses, Dissertations & Projects

Introduction: Guided implant surgery is becoming more prevalent among clinicians and is crucial for cases in which there are concerns about the proximity of the implant to vital anatomical structures, esthetic concerns, and the amount/quality of bone available. Surgical guides help with the angulation and positioning of the implant through the use of a CBCT scan and digital intraoral impression. However, there are some drawbacks with guided surgery. Heat that is generated during the osteotomy is one of the issues that has been of concern. The guide acts as a shield against the water irrigation from reaching the osteotomy …

Three-Dimensional Facial Morphology In Cantú Syndrome, Helen I Roessler, Kathleen Shields, Dorothy K Grange, Nine V A M Knoers, Gijs Van Haaften, Peter Hammond, Mieke M Van Haelst

2020-Current year OA Pubs

Cantú syndrome (CS) was first described in 1982, and is caused by pathogenic variants in ABCC9 and KCNJ8 encoding regulatory and pore forming subunits of ATP-sensitive potassium (K

Holistic Lifestyle Counseling By Physical Therapists: Current Practice And Barriers To Improvement, Savannah Grogan

Honors College Theses

Context: Unhealthy lifestyle habits are a significant risk factor for chronic disease and death in the United States of America. The healthcare system is largely focused on symptom-management and disease treatment with seemingly little regard for prevention, but physical therapists are particularly well-placed to improve patients’ health through lifestyle counseling and modification. Objectives: To assess the current state of holistic health promotion among physical therapists and to identify barriers to improving these practices. Design: An electronic survey was completed by physical therapists in and around the state of Kentucky. Descriptive statistics were used to assess participant demographics and the state …

A Comparison Of Heat Generated Between Carbide And Diamond Bur During Implantoplasty, Bryce Chun

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose: This study was conducted to evaluate heat generated during the implantoplasty procedure by comparing the heat generated using either a carbide or diamond round bur. Materials and Methods: Bovine ribs were selected as the osseous model for this study. Changes in temperature were measured using a digital thermometer (Extech SDL200 four channel thermometer, Extech instruments, Melrose MA). Ther k-thermocouples were positioned within the implant screw access, apex of the implant, and crestal bone adjacent to the implant and ambient air. 5 bovine rib bone blocks were prepared by place 5 cylindrical titanium grade 5 alloy large grit sand blasted …

Do Recipients Of Cash Transfer Scheme Make The Right Decisions On Household Food Expenditure? A Study From A Rural District In Pakistan, Aminah Jahangir, Shehla Zaidi, Jai K. Das, Shifa Habib

Community Health Sciences

Objective: To assess spending by beneficiaries of Benazir Income Support Programme on monthly food commodities, and contribution of the cash grant programme on purchase of nutritious foods.
Methods: The descriptive cross-sectional survey of households enrolled in the Benazir Income Support Programme was conducted during July and August, 2013, in Matiari district of the Sindh province of Pakistan. Monthly household food expenditure on food commodities and use of the cash grant on type of food purchased was assessed through structured interviews of the beneficiaries. Results were computed in 2013 Pak rupees and converted to 2018 United States dollar. Women beneficiaries were …

Intimate Partner Violence Against Women In Pakistan: A Review Of Qualitative Research, Tazeen S. Ali, Rida Farhan, Michelle Ayub

Community Health Sciences

Objective: To consolidate research data and provide an insight into areas that need further research regarding intimate partner violence.
Methods: The review targeted qualitative research-based studies done in the English language and conducted in Pakistan from 2008 to 2018 regarding intimate partner violence against women. A thorough search of Google Scholar and PubMed databases was done. Data from each selected article was extracted using a data-extraction template.
Results: Of the 2,479 results, 21(0.8%) articles were selected along with 4(0.16%) texts from grey literature. An in-depth analysis led to six broad categories: experiences/perspectives of married women facing intimate partner violence; perspectives …

Transcriptomic Responses To Coaggregation Between Oral Bacteria, V R Mutha Naresh

Student Works (2020-2029)

Cell-cell interactions between genetically distinct oral bacteria form macroscopic clumps known as coaggregates. These interactions, termed coaggregation contribute to the formation of highly structured multispecies communities in oral cavity, known as oral biofilms. Individual species also compete and collaborate with other neighboring species through metabolic interactions allowing growth of other species by coaggregation. This study involves the mixing of selected pairs of oral bacteria to form coaggregates and quantifying differential gene expression levels in each pair in comparison with mono-species coaggregation. The dual RNA-Seq approach made it possible to see how bacteria respond to one another leading to different metabolic …

Relative Contribution Of Arms And Legs Through Repetitive Assisted Sit-To-Stand Motion In Individuals With Incomplete Spinal Cord Injury, Abd Aziz Musfirah

Student Works (2020-2029)

Sit-To-Stand (SitTS) exercise is one of important prerequisites to achieve some functional independence goals in everyday life especially for individuals undergoing rehabilitation In general, the execution of SitTS in spinal cord injury (SCI) patients involves motor function in both upper and lower extremities. The use of arm support in particular is a very significant element while executing SitTS movement for SCI population. In addition, application of functional electrical stimulation (FES) onto the quadriceps muscles is one of the prescribed management for incomplete SCI to improve muscle action for simple lower limb movements. However, the relative contribution of upper and lower …

The Relationahips Between Health Behaviors Of Women And Health Locus Of Control Among Black Caribbean Women And Black American Women With Hypertension, Camelle Charles

Theses & Dissertations

Background

Millions of Caribbean women have migrated to the United States, and a sizeable number of these women and Black American women suffer from hypertension and other cardiovascular health problems. This research showed the comparison of health behaviors of both groups of women and the difference in their health outcomes. Today, there are more migrants in the world than ever before; an estimated 272 million international migrants in 2019, which is an increase in 51 million since 2010 (United Nations, 2019) and Caribbean migrants are a substantial portion of this pool. Approximately 4.4 million Caribbean immigrants reside in the U.S. …

Gardner's "Friends Like Henry: Everything Your Family Needs To Know About Finding, Training And Learning From An Autism Companion Dog" (Book Review), Xin "Lucy" Bai

The Christian Librarian

No abstract provided.

Shanti's "The Recovery Mama Guide To Your Eating Disorder Recovery In Pregnancy And Postpartum" (Book Review), Elizabeth A. Nolan

The Christian Librarian

No abstract provided.

Behers' "Spiritual Care For People Living With Dementia Using Multisensory Interventions: A Practical Guide For Chaplains" (Book Review), Craighton Hippenhammer

The Christian Librarian

No abstract provided.

Macdonald's "Teen Substance Use, Mental Health And Body Image: Practical Strategies For Support" (Book Review), Jessica Shuck

The Christian Librarian

No abstract provided.

Peptoid And Antibody-Based Gfp Sensors, Solomon Isu

Graduate Theses and Dissertations

In this work, we have made and characterized a pair of immunobiosensors for detecting the green fluorescent protein (GFP) in an aqueous matrix. An anti-GFP antibody-based biosensor was assembled to detect GFP, while a novel peptoid (N-substituted oligomers of glycine designated as IOS-1) biosensor was also assembled for GFP detection. A quartz crystal microbalance (QCM) gold sensor was used as the supporting substrate for self-assembly of the immunobiosensors. Gravimetric measurements of the QCM gold sensor during immunobiosensor construction and operation were available in real-time using a QCM instrument. X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, and Fluorescence microscopy were used …

Golf Director Competencies, Human Resource Management Practices And Customer Retention Within The Malaysian Golf Clubs, Partanian Samira

Student Works (2020-2029)

Golf is a popular sport worldwide. Many studies have described management competencies in several sport contexts and have revealed that human resource is the most common denominator for successful sports club practice. However, little work has been done to identify and explain contemporary Human Resource Management (HRM) practices of staff, including directors of golf clubs related to member retention. The purpose of this study was to examine the current level and the participants' quality perceptions in the relationship among competencies of directors, HRM practices of staff, and member retention within the Malaysian Golf Clubs to advance the causal relationships among …

Antioxidating Effect Of Ampelocissus Sp. (Isi Nyaru) On Streptozotocin-Induced Diabetic Rats, Zamri Elly Zulaikha

Student Works (2020-2029)

The Ampelocissus sp. locally known as Isi Nyaru has been traditionally used by native Malaysian for medical purpose. The tuber was extracted with hexane, petroleum-ether, chloroform, methanol and water solvents. The seperation and detection of bioactive compounds were done using Thin Layer Chromatography (TLC) and Gas Chromatography Mass Spectrometry (GCMS) methods. The TLC results showed the presence of phenolic acids, flavonoids and terpenoids. While in GCMS has revealed the presence of hydrocarbon groups such as alkene, ester and ether, amino acid groups, dicarboxylic acid and cyclic aromatic compound. The total phenol content and total flavonoid content were highest in methanolic …

How Nonprofit Healthcare Organizations Differ And Compare Based On Healthcare Professional Responses, Alexia Baugniet

Undergraduate Theses and Capstone Projects

As the demand for research increases over the years, healthcare will be in demand to improve. Currently, the effects of COVID-19 are bringing many questions to light in regards to the safety protocols in place in our various healthcare systems. In our world today, healthcare must be taken seriously, and programs should be put in place to help citizens better understand healthcare guidelines and safety protocols. In attempting to discover my passion and motivation, Suffolk University provided me the resources and tools to pursue my education in relation to Healthcare Management. For this senior capstone class, the overall goal was …

In Vitro Bioactivities Of Single Or Combined Extracts From Three Selected Asian Vegetables, Mahmud Norfaizah

Student Works (2020-2029)

Three underutilized folklore oriental-based vegetables Acalypha indica (AI), Centella asiatica (CA), and Sesbania grandiflora (SG) have been investigated for pharmacological activities relevant to wound healing process and synergistic actions. Single and combination of aqueous (A) and methanol (M) extracts of the three vegetables namely AI-A, CA-A, SG-A, AI-M, CA-M, SG-M, AI-A+CA-A, AI-A+SG-A, CA-A+SG-A, AI-M+CA-M, AI-M+SG-M, and CA-M+SG-M were assessed for stimulation of wound closure by normal human dermal fibroblast (NHDF) cells, antioxidant, protection against hydrogen peroxide (H2O2), stimulation of nitric oxide (NO) from RAW264.7 macrophages and antimicrobial activities. The combined vegetable extracts AI-A+CA-A (90.76%) showed the highest percentage of wound …

Establishment Of Organoids From Gastric Stem Cells And Their Use To Study The Role Of Aryl-Hydrocarbon Receptors, Shakila Afroz Taleb

Dissertations

Stem cells are powerful tools in different aspects of biomedical and translational research, including disease modelling, drug testing, and tissue engineering for regenerative medicine. However, isolation and culture of organ-specific stem cells are challenging tasks. Therefore, the biological features of many adult stem cells are not well studied and their involvement in the development of cancer is still controversial. Some immortal stem cell lines have been established and used as an alternative to studying features of organ-specific stem cells. The ability to grow cells in a scaffold-free, three-dimensional (3D) model system that mimics in vivo conditions would help in revealing …

The Effect Of Staphylococcus Aureus Exposure On White-Tailed Deer Trabecular Bone Stiffness And Yield, Emily Brooke Long

Graduate Theses

Osteomyelitis is an infection of the bone or bone marrow caused by the infiltration of bacteria, resulting in destructive inflammation, bone necrosis and abnormal bone remolding. With a growing number of osteomyelitis diagnoses, many of which are linked to Staphylococcus aureus (S. aureus), it is imperative to understand the pathology of S. aureus in relation to bone to provide better diagnostics and patient care. While the cellular mechanisms of S. aureus and osteomyelitis have been studied, little information exists on the biomechanical effects of such infections. We postulated that exposure to S. aureus for 72 hours would significantly decrease both …