Medicine and Health Sciences Commons^™

What's Happening: April 17, 2017, Maine Medical Center

What's Happening

No abstract provided.

Assessing The Efficacy Of A Local Resource Reference Manual On Home Modifications For Occupational Therapists In Roanoke, Virginia, Stephanie Peck

MOT Student Capstones

A qualitative research study was conducted to justify and promote occupational therapy's involvement within the home evaluation and home modification process. A resource reference manual was constructed following a systematic literal review where three key areas were identified as areas of interest; the impact of home modifications on participation and 3 performance within the home setting, occupational therapy's implementation of home modifications, and fall prevention with home modifications. With the results of the literature review supporting the involvement of occupational therapists within the home evaluation and home modification process, three objectives where identified to guide the study. These three objectives …

Comparison Of Stroke Cohorts Cared For By Two Different Specialties In A Practice-Based Tele-Stroke Population, Elias Atallah, Kimon Bekelis, Hassan Saad, Ayan Kumar, Justin Turpin, Randa Barsoom, Sophia Dang, Jonathan Li, Stavropoula Tjoumakaris, David Hasan, Maureen Deprince, Giuliana Labella, Robert H. Rosenwasswer, Pascal Jabbour

Department of Neurosurgery Posters

Conclusion

• Telemedicine is allowing for more patients suffering from AIS to receive care by dedicated stroke physicians including neurovascular surgeons.
• Our study does not find any difference in outcome between neurologists, who have traditionally managed stroke care, and neurosurgeons.
• Although ischemic stroke is a matter of multidisciplinary management, these surgeons are appropriately knowledgeable to prescribing IVrt-PA and concurrently performing MT in a highly-specialized stroke unit.

How Dental Hygiene Undergraduate Learning Is Influenced By Educational Videos, Alyssa L. Klenke

Dental Hygiene ETDs

How Dental Hygiene Undergraduate Learning is Influenced by Educational Videos

Abstract

This pilot experimental research study evaluated the efficacy of educational videos in comparison to traditional learning with print media and evaluated the student’s knowledge and retention of utilizing the periodontal screening and recording (PSR) method. The sample size consisted of 23 undergraduate students enrolled in their second year in a baccalaureate dental hygiene program. Participants were placed into two randomized groups, labeled Group A consisting of 12 students and Group B consisting of 11 students and evaluated with a 10 question pre test before exposure to the educational intervention, …

Behavioral Activation For Smoking Cessation And Mood Management Following A Cardiac Event: Results Of A Pilot Randomized Controlled Trial, Andrew M. Busch, Erin M. Tooley, Shira Dunsiger, Elizabeth A. Chattillion, John Fani Srour, Sherry L. Pagoto, Christopher W. Kahler, Belinda Borrelli

Arts & Sciences Faculty Publications

Background: Smoking cessation following hospitalization for Acute Coronary Syndrome (ACS) significantly reduces subsequent mortality. Depressed mood is a major barrier to cessation post-ACS. Although existing counseling treatments address smoking and depression independently in ACS patients, no integrated treatment addresses both. We developed an integrated treatment combining gold standard cessation counseling with behavioral activation-based mood management; Behavioral Activation Treatment for Cardiac Smokers (BAT-CS). The purpose of this pilot randomized controlled trial was to test feasibility, acceptability, and preliminary efficacy of BAT-CS vs. Standard of Care (SC). Methods: Participants were recruited during hospitalization for ACS and were randomly assigned to BAT-CS or …

Orthostatic Hypotension In Individuals With Alzheimer’S Disease: Case Study, Grace M. Irish

Nursing Capstones

No abstract provided.

Worldwide Use Of Triclosan: Can Dentistry Do Without This Antimicrobial?, Diana V. Macri

Publications and Research

No abstract provided.

Synthetic Cannabinoids Effects On The Brain Versus Cannabis, Andrea M. Petersen

Nursing Capstones

No abstract provided.

Developing Fluorogen Activating Protein-Fluorescent Protein Fret Pairs For Live Cell Imaging, Genevieve Kate Phillips

Biomedical Sciences ETDs

Fluorogen activating proteins (FAPs) are genetically encoded tags made from single chain antibody fragments (scFv) designed to bind fluorogens with high specificity. Both the fluorogen and FAP can be modified to provide flexibility in properties such as affinity, membrane permeability, spectra, and quantum yield. The fluorogen Malachite Green (MG) has two excitation peaks, the maximum at 630 nm and a secondary peak at 450 nm. The emission spectra of blue-emitting fluorescence proteins, such as mCerulean (mCer), overlap with the MG secondary peak, generating a FRET pair with large Stokes shift emission. Using 405 nm excitation of mCer, we observe acceptor …

Obesity-Induced Endoplasmic Reticulum Stress Causes Lung Endothelial Dysfunction And Promotes Acute Lung Injury, Dilip Shah, Freddy Romero, Zhi Guo, Jianxin Sun, Jonathan C. Li, Caleb Kallen, Ulhas P. Naik, Ross Summer

Center for Translational Medicine Faculty Papers

Conclusion

• Lung endothelial dysfunction in DIO mice coincides with increased endoplasmic reticulum (ER) stress.
• Fatty acids in obese serum induce ER stress in the pulmonary endothelium leading to pulmonary endothelial cell dysfunction.
• Reducing protein load in the endoplasmic reticulum of pulmonary endothelial cells might protect against ARDS in obese individuals.

School Of Nursing News, Georgia Southern University

Nursing: News & Publications (2013-2023)

• RN to BSN Program Ranked Nationally

Return To Nursing: A Meta-Synthesis Of Academic Bridging Programs’ Effect On Internationally Educated Nurses, Edward V. Cruz, Rhea Faye Felicilda-Reynaldo, C. Patricia Mazzotta

The Qualitative Report

This meta-synthesis explored the effect of bridging programs on internationally educated nurses (IENs). Eight papers that met the inclusion criteria were selected for this review. There were 437 participants from eight studies who come from different parts of the globe and who settled in either Australia, Canada, New Zealand, or the United Kingdom. Using a grounded theory approach for data analysis, four effects of bridging programs on IENs were identified. These are: (a) the concepts from the regulatory body, the client-centred care; (b) do something better for us, for our future; (c) we have to learn English; and, (d) faculty, …

Medical School Watercooler Newsletter - April 16, 2017, Lindsey Lyle

Watercooler Newsletter

This is the April 16, 2017 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA Health to Offer Free Skin Cancer Screenings

Inaugural Resident and Fellow Expo Set for May 23

Anatomy Outreach Provides Interactive Experience for High School Students

Dr. William Gerthoffer Receives Joseph R. Rodarte Award for Scientific Distinction

Pediatrics Hosting Grand Rounds This Week

Compassion Satisfaction And Compassion Fatigue Among Pediatric Nurses And The Impact On Patient Satisfaction, Maribeth Thornton

Nursing ETDs

Compassion fatigue and compassion satisfaction are two inter-related concepts. Individuals in helping professions may occasionally face compassion fatigue from giving so much of themselves to others. Compassion fatigue has been studied in a variety of settings: medical, social work, nursing, law enforcement, and fire departments, to name a few. While some researchers have studied nurses, little published work has focused exclusively on nurses who care for specialty pediatric populations. Additionally, there is scant research on whether compassion satisfaction and compassion fatigue are associated with patient satisfaction. The purpose of this study was to determine the level of compassion satisfaction and …

Modeling The Trauma-Antisociality Relationship As Mediated By World Assumptions: Associations With Gender And Drinking Outcomes, Kathryn Fokas

Psychology ETDs

Previous research has established links between traumatic experiences and externalizing pathology including substance use and antisocial behavior, but little is known about potential mechanisms linking these phenomena. This study proposed a novel conceptual model linking these phenomena via the cognitive mechanism of negative world assumptions, or beliefs about the inherent dangerousness and unpredictability of life and others. Given previous mixed findings, this study also sought to explore potential interactions between gender and these phenomena. It was hypothesized that, within a sample of adults seeking alcohol treatment, world assumptions would mediate and gender would moderate the trauma-antisociality association. It also was …

Pseudomonas Aeruginosa-Derived Rhamnolipids And Other Detergents Modulate Colony Morphotype And Motility In The Burkholderia Cepacia Complex, Steve P. Bernier, Courtney Hum, Xiang Li, George A. O'Toole, Nathan A. Magarvey, Michael G. Surette

Dartmouth Scholarship

Competitive interactions mediated by released chemicals (e.g., toxins) are prominent in multispecies communities, but the effects of these chemicals at subinhibitory concentrations on susceptible bacteria are poorly understood. Although Pseudomonas aeruginosa and species of the Burkholderia cepacia complex (Bcc) can exist together as a coinfection in cystic fibrosis airways, P. aeruginosa toxins can kill Bcc species in vitro. Consequently, these bacteria become an ideal in vitro model system to study the impact of sublethal levels of toxins on the biology of typical susceptible bacteria, such as the Bcc, when exposed to P. aeruginosa toxins. Using P. aeruginosa spent medium …

Reduction In Activity By Noxious Chemical Stimulation Is Ameliorated By Immersion In Analgesic Drugs In Zebrafish, Javier Lopez-Luna, Qussay Al-Jubouri, Waleed Al-Nuaimy, Lynne U. Sneddon

Anesthesia and Analgesia Collection

Research has recently demonstrated that larval zebrafish show similar molecular responses to nociception to those of adults. Our study explored whether unprotected larval zebrafish exhibited altered behaviour after exposure to noxious chemicals and screened a range of analgesic drugs to determine their efficacy to reduce these responses. This approach aimed to validate larval zebrafish as a reliable replacement for adults as well as providing a high-throughput means of analysing behavioural responses. Zebrafish at 5 days postfertilization were exposed to known noxious stimuli: acetic acid (0.01%, 0.1% and 0.25%) and citric acid (0.1%, 1% and 5%). The behavioural response of each …

Fracture Fixation In The Operative Management Of Hip Fractures (Faith): An International, Multicentre, Randomised Controlled Trial, Aaron Nauth, Aaron T. Creek, Abby Zellar, Abdel Rahman Lawendy, Adam Dowrick, Ajay Gupta, Akhil Dadi, Albert Van Kampen, Albert Yee, Alexander C. De Vries, Alexander De Mol Van Otterloo, Alisha Garibaldi, Allen Liew, Allison W. Mcintyre, Amal Shankar Prasad, Amanda W. Romero, Amar Rangan, Amber Oatt, Amir Sanghavi, Amy L. Foley, Anders Karlsten, Andrea Dolenc, Andrew Bucknill, Andrew Chia, Andrew Evans, Andrew Gong, Andrew H. Schmidt, Andrew J. Marcantonio, Andrew Jennings, Angela Ward, Angshuman Khanna, Anil Rai, Anke B. Smits

Bone and Joint Institute

© 2017 Elsevier Ltd Background Reoperation rates are high after surgery for hip fractures. We investigated the effect of a sliding hip screw versus cancellous screws on the risk of reoperation and other key outcomes. Methods For this international, multicentre, allocation concealed randomised controlled trial, we enrolled patients aged 50 years or older with a low-energy hip fracture requiring fracture fixation from 81 clinical centres in eight countries. Patients were assigned by minimisation with a centralised computer system to receive a single large-diameter screw with a side-plate (sliding hip screw) or the present standard of care, multiple small-diameter cancellous screws. …

Harlem Hospital's Journey To Patient Navigation, Christine W. Thorpe

Publications and Research

This essay discusses the history of 20th century black migration to Harlem, New York and the utilization of Harlem Hospital. This examination is based on New York newspaper articles in the 1920’s. They tell the story, from a journalist’s perspective, of the challenges African Americans experienced in their interactions with Harlem Hospital. The implicit communication of segregation of Harlem Hospital at that time is connected to the development of patient navigation in the 1970’s. The creation of patient navigation will be discussed in the context of historical health disparities that are increasingly manifested today.

Novel Genetic Variants Associated With Child Refractory Esophageal Stricture With Food Allergy By Exome Sequencing., Min Yang, Min Xiong, Huan Chen, Lanlan Geng, Peiyu Chen, Jing Xie, Shui Qing Ye, Ding-You Li, Sitang Gong

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Refractory esophageal stricture (RES) may be attributed to food allergy. Its etiology and pathogenesis are not fully understood. Identification of novel genetic variants associated with this disease by exome sequencing (exome-seq) may provide new mechanistic insights and new therapeutic targets.

METHODS: To identify new and novel disease-associating variants, whole-exome sequencing was performed on an Illumina NGS platform in three children with RES as well as food allergy.

RESULTS: A total of 91,024 variants were identified. By filtering out 'normal variants' against those of the 1000 Genomes Project, we identified 12,741 remaining variants which are potentially associated with RES plus …

Considerations For The Use Of Medical Devices In Dermatology., Jordan Wang, Dorota Z. Korta, Christopher B. Zachary

Department of Dermatology and Cutaneous Biology Faculty Papers

This manuscript addresses the significant considerations concerning the development and use of medical devices in dermatology. With the rapidly growing demand and booming market for medical devices, especially lasers, it is crucial that dermatologists become familiar with the nuances associated with supporting clinical studies, consumer-driven marketing strategies, and the complex relationships that exist between physicians, industry, and consumers. An examination of these relationships includes an overview of the potential biases pertaining to advisory panels and treating clinicians. The aim of this paper is to serve as an introduction to the background of medical devices and to offer dermatologists important information …

Primary Adrenal Non-Hodgkin Lymphoma: A Case Report And Review Of The Literature, Nanik Ram, Owais Rashid, Saad Farooq, Imran Ulhaq, Najmul Islam

Section of Diabetes, Endocrinology and Metabolism

Background: Lymphomas are cancers that arise from the white blood cells and have been traditionally divided into two large subtypes: Hodgkin and non-Hodgkin lymphoma. B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma; almost 85% of patients with lymphoma have this variant. Lymphomas can potentially arise from any lymphoid tissue located in the body; however, primary adrenal non-Hodgkin lymphoma is extremely rare. We report the history, examination findings, and laboratory results of a 50-year-old man diagnosed with a primary left adrenal diffuse large B-cell lymphoma.

CASE PRESENTATION: A 50-year-old Pakistani man presented to our hospital with progressively increasing pain …

The Effects Of Hyperhomocysteinemia On Hypertension In Adults, Kimberly Ford

Nursing Capstones

No abstract provided.

Effectiveness Of Methadone For Treatment Of Heroin Use Disorder, Megan M. Newberry

Honors Capstones

Capstone submitted as a requirement for BSU Honors Program.

A Study Of Skin-To-Skin Care During Cesarean Births, Kristen Bertrand

Research Horizons Day Posters

No abstract provided.

Preliminary Validation Of Capture With Uti Samples, Elizabeth Gates

Research Horizons Day Posters

No abstract provided.

Assessing The Efficacy Of Recommended Antiseptics For Killing Bacterial Growth In Neonatal Blue Bulb Syringes: Addressing A Clinical Issue, Linda A. Hanson

Research Horizons Day Posters

No abstract provided.

Treatment Considerations Of Gout In The Patient With Chronic Kidney Disease In The Primary Care Setting, Angela Mackner

Nursing Capstones

No abstract provided.

Safe And Efficient Silencing With A Pol Ii, But Not A Pol Lii, Promoter Expressing An Artificial Mirna Targeting Human Huntingtin, Edith L. Pfister, Kathryn O. Chase, Huaming Sun, Lori A. Kennington, Faith Conroy, Emily Johnson, Rachael Miller, Florie Borel, Christian Mueller

Dartmouth Scholarship

Huntington's disease is a devastating, incurable neurodegenerative disease affecting up to 12 per 100,000 patients worldwide. The disease is caused by a mutation in the Huntingtin (Htt) gene. There is interest in reducing mutant Huntingtin by targeting it at the mRNA level, but the maximum tolerable dose and long-term effects of such a treatment are unknown. Using a self-complementary AAV9 vector, we delivered a mir-155-based artificial miRNA under the control of the chicken β-actin or human U6 promoter. In mouse brain, the artificial miRNA reduced the human huntingtin mRNA by 50%. The U6, but not the CβA promoter, produced the …

Predictors Of Hpv Vaccination Series Completion In Philadelphia Adolescents, Karie Youngdahl, Mph, Ami S. Patel, Phd, Mph, Amy E. Leader, Drph, Mph

JCPH Alumni

Research Aim:

This study analyzed data from the Philadelphia KidsPlus Immunization information System (IIS) to look at factors associated with HPV vaccine series completion.

Note:

Student capstone presentation also available at: http://jdc.jefferson.edu/mphcapstone_presentation/190/