Medicine and Health Sciences Commons^™

High-Resolution Physical Map For Chromosome 16q12.1-Q13, The Blau Syndrome Locus., Xiaoju Wang, Helena Kuivaniemi, Gina Bonavita, Charlene J Williams, Gerard Tromp

Charlene Williams

BACKGROUND: The Blau syndrome (MIM 186580), an autosomal dominant granulomatous disease, was previously mapped to chromosome 16p12-q21. However, inconsistent physical maps of the region and consequently an unknown order of microsatellite markers, hampered us from further refining the genetic locus for the Blau syndrome. To address this problem, we constructed our own high-resolution physical map for the Blau susceptibility region. RESULTS: We generated a high-resolution physical map that provides more than 90% coverage of a refined Blau susceptibility region. The map consists of four contigs of sequence tagged site-based bacterial artificial chromosomes with a total of 124 bacterial artificial chromosomes, …

Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

Use your break to expand your knowledge by checking out the many Grand Rounds posted in the Jefferson Digital Commons. Topics range from nasal reconstruction to sexuality and aging. With hours of Grand Rounds to experience (see some samples below), your holiday will transform from boredom to excitement! Happy holidays from the Jefferson Digital Commons!

A Word From The Writing Center (November 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Stylish academic writing
• The Write Stuff

Successes And Limitations Of Hepatitis C Screening In The Inpatient Setting: Initial Impact Of Pa Act Of 87 (Apha Roundtable Discussion), Madalene Zale, Mph Candidate, Ashley Park, Mph, Francis Nelson, Ms, Priya Mammen, Md, Mph

College of Population Health Lectures, Presentations, Workshops

The Problem:

• Estimated 3.2 million in US with chronic HCV; Baby Boomers 5 times more likely to be infected compared to other cohorts
• Complex nature of HCV requires confirmation of HCV Ab screens to determine management and treatment needs.

Round table held at 2017 Annual APHA meeting in Atlanta, Georgia

Reaching High-Risk Patient Populations Through Emergency Department Opt-Out Hiv Testing: A Retrospective Chart Review, Tyler G. Boyce, Ba, Priya Mammen, Md, Mph

CwiC Posters

Specific Aims and Hypotheses:

This study aimed to identify socioeconomic (SE), sexual, and other risk factors (RFs), among patients diagnosed with HIV infection through an emergency department-based opt-out HIV screening program, and to examine trends in intravenous drug use (IVDU) as a RF.

• H1: Unsafe sexual practices are the most commonly reported RF.
• H2: Role of IVDU as a RF has increased over the time period studied.

Poster presented at 2017 APHA conference in Atlanta Georgia.

Borders And Blood Pressure: Understanding The Role Of Acculturation In A Hypertension Diagnosis Among Hispanic Americans: 2014 California Health Interview Survey, Lia Scalzo, Mph, Hee-Soon Juon, Phd, Msn, Russell K. Mcintire, Phd, Mph

College of Population Health Posters

Background:

In the U.S. Hispanic population overall, heart disease is the leading cause of death. The prevalence of hypertension among Mexican American immigrants is lower than the general population, yet it is on the rise. Health risks among Hispanics vary depending on their length of stay in the US (as proxy measure of acculturation). The purpose of this study was to examine the association between acculturation and the individual's likelihood of being diagnosed with hypertension among Hispanic Americans.

Methods:

We used data from the 2014 California Health Interview Survey (CHIS) and performed univariate analysis to examine racial differences in prevalence …

Climate Change And Resulting Floods: Using Social Capital To Strengthen Community Resilience In Eastwick, Philadelphia A Known Floodplain, Natasha Bagwe, Md, Mph, Richard Pepino, Phd, Mss, Erin Johnson, Mph, Msn, Rn, Julie Becker, Phd, Mph

College of Population Health Posters

• Climate change will produce intense weather events like increased precipitation and flooding

• Based on climate projections, Philadelphia will be hotter and wetter, and will experience more frequent and intense weather events (OOS, 2016)

•Floods are the second most common hazards in our city (OEM, 2017)

• Vulnerable population such as children, people of color, elderly population and people with disability are severely impacted by climate change

Poster presented at AHPA conference in Atlanta Georgia, United States.

A Pilot Study For Enhancing Postpartum Discharge Instructions For Incision Care: Assessment Of Comprehension, Rebekah Jo Mccurdy, Md, Rebecca Lawrence, Bs, Sarah Cohen, Bs, Jason K. Baxter, Md, Mscp

CwiC Posters

Literacy and Health Care

• 14.5% of United States is illiterate 1

• Reading level of most medical forms is 10th grade 2

Improving Outcomes with a Visual Aid

• Cesarean Surgical Site Infection (SSI) rate is 5% 3

• A patient with a SSI can be 2 times as expensive 4

• Visual aids improve information recall 8 and confidence in wound care 5

Study Objectives

1. To evaluate the readability of the cesarean wound care discharge instructions relative to the patient population’s reading level

2. To conduct a pilot Randomized Control Trial (RCT) to evaluate the effectiveness of …

Assessing Variability In End-Of-Life Intensity Of Care After Out-Of-Hospital Cardiac Arrest, Polina Ferd, Md Candidate, David Karp, Musa, Alexis Zebrowski, Phd Candidate, Brendan G. Carr, Md, Ma, Ms

CwiC Posters

Out of hospital cardiac arrest (OHCA) affects over 300,000 Americans per year.1 Many factors affect the outcomes and overall OHCA survival in a community; some of these include an individual’s characteristics such as age, co-morbid conditions, availability of an AED on scene, time to CPR, and the characteristics of the hospital they are treated at.1,2 Directly following resuscitation from cardiac arrest, the individual is at risk of developing numerous problems caused by sequelae of ischemic injury sustained during the arrest. The national average rate of survival to discharge is only 10%.2,3 Many of these factors are modifiable and provide an …

Examining The Role Of Diagnosis In The Emergency Department Experience, Danielle Kovalsky, Bs, Angela Gerolamo, Phd, Aprn, Bcps, Amanda Doty, Ms, Alexzandra Gentsch, Lsw, Annemarie Jutel, Rn, Bphed (Hons), Phd, Kristin L. Rising, Md, Ms

CwiC Posters

Study Objective:

To explore the social, functional, and emotional needs that patients want addressed when seeking a diagnosis at their ED visit.

Baseline Assessment Of Providers' Perspectives On Integrating Community Health Workers Into Primary Care Teams To Improve Diabetes Prevention, Ariel Brown, Garseng Wong, Radhika Gore, Mark Schwartz, Md

CwiC Posters

• Type 2 Diabetes Mellitus (T2DM) affects 11% of U.S. adults

• Additional 35% considered pre-diabetic, at-risk for developing T2DM1

• Bellevue Hospital and the VA NY Harbor Hospital disproportionately affected: 2x the prevalence in the general population, and increasing2

• Only 55% of adults receive recommended preventive services3

• Panel management: each care team is responsible for preventive care, disease management, and acute care of a patient panel

• Community health worker (CHW): non-clinical frontline public health professional trained in behavioral counseling, care follow-up, program referrals, and health education4-8

• Come from the community that they serve, so they …

Depression, Cognition, & Social Determinants Of Health: Assessing Associations In Older African Americans With Diabetes, Jeremiah Davis, Robin Casten, Phd, Barry W. Rovner, Md

CwiC Posters

Social determinants of health have been widely identified as characteristics of one’s social and economic climate that affect one’s health outcomes1. (see Graphic 1)

The Alzheimer’s Association indicates that rates of Alzheimer’s disease (AD) and other forms of dementia are two times higher in older African Americans than their white counterparts2. People who have diabetes are also at an increased risk.

The prevalence and co-morbidity of depression among older Americans with diabetes (both with and without cognitive impairment) has been well established3.

Understanding the effect that social determinants of health have on the onset and progression of dementia and depression …

Leading Causes Of Death In Vietnam, Lindsey Roth

CwiC Posters

Vietnam is currently facing a public health crisis. Rates of chronic and preventable diseases are climbing, in addition to mortality rates from these diseases. If nothing is done to halt these rising rates, the health of the Vietnamese people will only continue to decline. Although there may be many factors contributing to these high death rates due to chronic diseases, risky health behaviors, such as smoking, and the state of the healthcare system can be considered two main contributors to the leading causes of death in Vietnam. The high smoking rates and high costs of healthcare are hindering the health …

Initiating C.H.E.W. At Maternity Care Coalition, Haley Wicklum, Rickie Brawer, Mph, Phd

CwiC Posters

The purpose of this project is to provide access to healthy and affordable foods to the families involved in Maternity Care Coalition’s Early Head Start program as means to reduce obesity in the 0-3 year old children. Implementing the C.H.E.W. (Cultivating Healthy Eating and Wellness) program, which includes a new food buying club where families can access healthy food at whole sale prices as well as nutrition education workshops throughout the year, will provide access to the healthy and affordable foods needed. The program is focused on pregnant women and young families with children 0-3 years of age to attempt …

All Limbs Lead To The Trunk, Daniel E. Graves, Phd, Darryn Atkinson, Phd, Pt

Department of Rehabilitation Medicine Posters

This poster describes the development of and the psychometric properties of the trunk scale that measures the voluntary motor ability in the thoracic and upper lumbar regions. The function of the trunk musculature has far reaching implications, particularly in persons with SCI, where postural control and voluntary movement are compromised to varying degrees. Precisely coordinated muscle actions must occur in the appropriate sequence, duration, and combination for the optimal movement function and maintenance of balance and posture during dynamic activities. Trunk mobility is required for nearly all mobility tasks, particularly transitional movements such as rolling, supine to sit, and sit …

The Handoff Culture: Can We Change How An Icu To Floor Transfer Works?, Kristin Lohr, Md, Grant Turner, Md, Allison Greco, Md

House Staff Quality Improvement and Patient Safety Conference (2016-2019)

Handoffs between providers have increased following the implementation of the 2011 Accreditation Council for Graduate Medical Education (ACGME) work hour restrictions. Properly structured and timed handoffs are essential to patient safety.1 Despite this, studies have shown that errors in code status, medication allergies, and important updates to the problem list are common, all of which can lead to adverse outcomes to patients.2

At Thomas Jefferson University Hospital (TJUH) the 2016 Safety Culture Survey revealed that across all specialties, 37% of residents felt that things “fall through the cracks” when transferring patients from one unit to another.

Our interdepartmental Housestaff Quality …

Jefferson Conference Sponsorship

Office of Diversity & Inclusion Initiatives Newsletter

Featuring:

• National Medical Association
• Gay and Lesbian Medical Association

Graduate Medical Education

Office of Diversity & Inclusion Initiatives Newsletter

To expand and enhance diversity and inclusion for our resident physicians, three initiatives targeting GME have been implemented.

Faculty Initiatives

Office of Diversity & Inclusion Initiatives Newsletter

New URM faculty welcome meeting

SKMC is committed to the career development of all faculty at Jefferson but recognize that those from a racial or ethnic group that is underrepresented in medicine, a woman in a specialty in which women are underrepresented and/or those who self-identify as lesbian, bisexual, gay, transgender, or questioning sexual identity may have unique concerns such as reducing isolation or finding a mentor with a similar background. Dr. Karen Novielli, Vice Dean for Faculty Affairs and Professional Development, along with Dr. Bernie Lopez, Associate Dean for Diversity and Community Engagement, meet individually with new faculty from …

Pipeline Programs

Office of Diversity & Inclusion Initiatives Newsletter

Pipeline programs are designed to prepare and inspire students to pursue careers in medicine and medical research. SKMC is committed to providing experiences and education to middle school, high school, college, and graduate students from groups underrepresented in the health care fields to increase the pool of qualified candidates applying to careers related to medicine and medical research.

Our programs:

• The Jefferson STEP-UP Medicine Program
• Future Health Professions Program (FHPP)

Diversity And Inclusion Education

Office of Diversity & Inclusion Initiatives Newsletter

In the 2016-2017 academic year, two then-second year SKMC students. Linda Magana and Kevin Guttierez, created and conducted a “Race and Medicine” course that first year SKMC students could receive credits for their Humanities Course. The Office of the Dean at SKMC has created a new lecture series called, “Confronting Racism, Bias, and Social Injustice in Healthcare.” This first-of-akind at Jefferson educational series is meant to educate on this important topic and to allow us to begin the discussions needed to move us forward in our quest to provide the best patient care. The content was developed by Drs. John …

Skmc Council On Diversity And Inclusion

Office of Diversity & Inclusion Initiatives Newsletter

The SKMC Council for Diversity and Inclusion (D & I) is charged with reviewing and assessing the status and effectiveness of diversity and inclusion initiatives at SKMC and makes recommendations regarding initiatives, policies, and resources needed to achieve desired outcomes. Headed by Mark L. Tykocinski, MD, the Anthony F. and Gertrude M. DePalma Dean of SKMC, and cochaired by Dr. Bernie Lopez, the Council determines the course of diversity and inclusion at SKMC with input from members who are deans, department chairs, faculty, administrators, residents and students.

Odii Student Organizations

Office of Diversity & Inclusion Initiatives Newsletter

Featuring:

• Student National Medical Association (SNMA)
• The Asian Pacific American Medical Student Association (APAMSA)
• JeffLGBTQ
• Veterans Health Initiative
• Jewish Student Association (JSA)
• Refugee Health Partners (RHP)
• Student Advisory Board
• Latino Medical Student Association (LMSA)
• Medical Spanish Translator Program

A Message From The Associate Dean For Diversity And Community Engagement, Bernard Lopez, Md

Office of Diversity & Inclusion Initiatives Newsletter

Diversity: the richness in human differences. Why is diversity important? A wide variety of experiences and points of view mean that we get to look at issues from all angles rather than just one. Inclusion: the active, intentional, and ongoing engagement with diversity. Why is inclusion important? It is not enough to have diversity - inclusion means that we value and cherish the wide variety of experiences and viewpoints. Creating and enhancing this environment is important as we set the stage to provide service to our most important customer - our patients.

Since September 2013 when I was appointed as …

Symptomatic Choledocholithiasis After Cholecystectomy, Joseph Spataro, Mazen Tolaymat, Charles Kistler, Michael Jacobs, Jeffrey Fitch, Monjur Ahmed

Department of Medicine Posters

Background

• Clinical manifestations of choledocholithiasis include biliary colic, obstructive jaundice, pancreatitis, and acute cholangitis
• Secondary common bile duct (CBD) stones are common when the gallbladder is intact or after recent cholecystectomy (CCY) whereas recurrent stones develop >3 years after surgery1,2
• Patients with retained CBD stones after CCY may be asymptomatic for years and there is limited data on their pattern of presentation
• Despite known predisposing conditions and risk factors for recurrent biliary disease, the role of intraoperative cholangiography (IOC) during CCY remains controversial

Poster presented at: World Congress of Gastroenterology at ACG 2017 in Orlando Florida, United States.

Delaware Health Sciences Alliance Global Health Symposium: Refugee And Immigrant Access To Care Locally And Globally

Global Health Events

Welcome to the 6th annual Global Health Symposium! As always, we are pleased to highlight the latest in our growing Global Health interests across the DHSA. The Delaware Health Sciences Alliance is a partnership of:

• Christiana Care Health System
• Jefferson Philadelphia University & Thomas Jefferson University
• Nemours / Alfred I. duPont Institute for Children
• University of Delaware

A Word From The Writing Center (October 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Selecting a target journal using journalguide.com
• Teaching and Communication Skills workshops

One Jefferson News October 2017, Performance Excellence

One Jefferson News

Over the past month, we have continued our One Jefferson journey and achieved a number of integration successes for the organization as well as our patient and student communities. In this issue of One Jefferson News, we invite you to join us in celebrating the recent addition of Kennedy to Jefferson Health and a new college structure for Jefferson (Philadelphia University + Thomas Jefferson University) set to launch in 2018.

During this time of continued organizational evolution, we recognize the importance of frequent communications and celebrating the many accomplishments of our talented team. If you have questions or ideas, we …

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 66, Issue 2, Fall 2017

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

• Introducing the New Jefferson: One Name. Two Legacies. Infinite Possibilities
• The PhiladelphiaU Story: A History of Change and Innovation
• Two Alumnae, One Vision: A New Home Base for All Graduates
• Second Opinions for Docs, Second Chances for Patients: The Jefferson Angioplasty Center Helps Cardiac Patients Avoid Open Heart Surgery
• Dean's Column
• Findings: Molecule May Help Maintain Brain's Synaptic Balance
• The Families We Choose: A Message from Elizabeth Dale
• On Campus
• Basil Harris, MD '02: Merging Medicine, Engineering, and Design to Revolutionize Digital Healthcare
• Big Things, Small Beginnings: Jefferson Surgeons Are Exploring New Therapies That May Make Standard …

A Word From The Writing Center (September 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Writing Tip: Sentences that start with the word there
• Communication Skills Workshop Series: Communicate Like a Pro: Think like a...