Medicine and Health Sciences Commons^™

Sexual Health Education In New Mexico Public Secondary Schools, Elizabeth Dickson

Nursing ETDs

Previous research has shown that comprehensive sexual health education (SHE) can significantly reduce risky sexual behavior and can increase protective behavior in adolescents. While an important component for all adolescents, this is particularly important for adolescents at high risk for adverse health outcomes, such as unplanned adolescent pregnancy and sexually transmitted infections. The aims of this descriptive study were to explore the content and delivery of SHE in New Mexico and to describe influences on decisions pertaining to implementation of state SHE policy. The social ecological model (SEM) was used as a theoretical framework to better understand levels of influence …

Next Generation Sequencing Technologies For Real-Time Genotyping And Targeted Sequencing For Precision Medicine, Priyanka Rawat

Biomedical Engineering ETDs

Astounding success of Human genome project and accelerating success of sequencing technologies have enabled $ 1000 genome goals possible. But, this is still far-fetched from the reach of many resource refrained populations with high genetic variations causing lethal genetic diseases. Based on present technology principles, I have developed prototypes for affordable, scalable and customizable point-of-care genotyping and targeted sequencing. Ion-sensitive field effect transistors with novel read-out and signal amplification techniques are used for laying foundation of possible ISFET based allele-arrays. Sequencing-by-synthesis based full-fledge sequencer is made with novel immobilization, flow-cell and data acquisition methods for massive sequenciing.

Understanding Behavioral Health And Treatment Engagement With Former Users Of Prenatal Substances: A Strengths-Focused Mixed Methods Inquiry, Jennifer G. Benson, Peggy Maclean, Andrew Hsi, Sarah J. Erickson

Psychology ETDs

Accessible services for users of prenatal substances are lacking, and treatment engagement is poor with services that are available. Furthermore, legal consequences are often punitive, which ultimately damages the well-being of mother and child. Milagro and FOCUS are two New Mexico programs that provide comprehensive, coordinated care, including medication-assisted treatment, to former users of prenatal substances during pregnancy (in the Milagro Program) and for three years post-birth (in the FOCUS Program). This mixed methods study explored the lived experiences of women from this complex, high-risk population, using a high-engagement sample of women who utilized services at both Milagro and FOCUS. …

Cholesterol Regulation Of Pulmonary Endothelial Calcium Entry Following Chronic Hypoxia, Bojun Zhang

Biomedical Sciences ETDs

Chronic hypoxia (CH)-induced pulmonary hypertension (PH) is associated with diminished ATP-induced endothelial Ca2+ entry as well as membrane cholesterol in pulmonary arteries. Store-operated Ca2+ entry (SOCE) and depolarization-induced Ca2+ entry are major components of the response to ATP and are similarly decreased after CH. Because endothelium-dependent vasodilation is closely associated with pulmonary endothelial [Ca2+]i, the blunted agonist-induced Ca2+ influx in pulmonary artery endothelial cells (PAEC) may contribute to the development of CH-induced PH. Interestingly, impaired agonist-induced Ca2+ influx in PAEC following CH can be restored by membrane cholesterol supplementation. In the current studies, we hypothesized that impaired Ca2+ entry in …

The Assessment Of A School-Based Dental Program, Peggy H. Hyden

Dental Hygiene ETDs

The Assessment of a School-Based Dental Program

by

Peggy H. Hyden

B.S., Dental Hygiene, Caruth School of Dental Hygiene, Texas A&M College of Dentistry, 1979 M.S., Dental Hygiene, University of New Mexico, 2018

ABSTRACT Purpose: The purpose of this study was to compare non-participants and participants of a school-based dental program and assess the utilization and satisfaction of services offered. Methods: Sixty-seven hundred questionnaires, containing 20 questions, were distributed to the parents/guardians of the Carlsbad and Loving school systems. Surveys were taken home by the students, given to the parent/guardians and returned within 1 week. Descriptive statistics was used to …

11-07-2017 Hsc Committee Meeting Minutes, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Home Visiting: Discovering What Works For Increasing Referrals, Theresa Cruz, Leona Woelk, Ivy Cervantes

Reports & Documents

The purpose of this work was to identify barriers providers may experience with regard to referring patients to home visiting (HV) programs and to determine potential intervention strategies that could be used to increase provider referrals, initially in Bernalillo County.

12-05-2017 Hsc Committee Agenda, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Post-Transcriptional Regulation Of Addiction-Related Behaviors: Opposing Roles Of Nucleus Accumbens Mir-495 And Hud, Robert J. Oliver Jr

Biomedical Sciences ETDs

Substance use Disorders (SUDs) are characterized by chronic relapse after periods without symptoms. This has been hypothesized to stem from persistent alterations in corticolimbic circuit function and structure caused by drug-induced alterations in addiction-related gene (ARG) expression. Transcriptional and epigenetic regulation of ARGs and addiction-like behaviors have been well characterized but the role of post-transcriptional regulation is an understudied, yet promising field. RNA binding proteins (RBPs) are one post-transcriptional regulator of mRNA stability. HuD is a neuronal specific RBP that stabilizes mRNAs and is regulated by neuronal activity and cocaine. Another type of post-transcriptional regulator, microRNAs (miRNAs), are non-coding RNAs …

Notice Of 12-05-2017 Hsc Committee Meeting, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Discourse Changes Following Severe Traumatic Brain Injury: A Longitudinal Study, Elizabeth Young

Speech and Hearing Sciences ETDs

Purpose: There are few longitudinal data charting recovery of discourse skills following severe traumatic brain injury (TBI). Limited knowledge about the trajectory of discourse recovery and the best tools for assessing communication abilities in persons with TBI (PWTBIs) restricts detection of communication impairment and the ability to make informed prognostic judgments following TBI. This study sought to contribute longitudinal data to the research base, using clinically efficient measures that are sensitive to communication deficits associated with TBI and that use nuanced scoring systems to provide detailed characterization of discourse.

Methods: Twenty-three PWTBIs completed picture description tasks at 3 (or 6) …

Proposed Method For Measuring The Let Of Radiotherapeutic Particle Beams, Stephen D. Bello

Physics & Astronomy ETDs

The Bragg peak geometry of the depth dose distributions for hadrons allows for precise and effective dose delivery to tumors while sparing neighboring healthy tissue. Further, compared against other forms of radiotherapeutic treatments, such as electron beam therapy (EBT) or photons (x and \(\gamma\)-rays), hadrons create denser ionization events along the particle track, which induces irreparable damage to DNA, and thus are more effective at inactivating cancerous cells. The measurement of radiation's ability to inactivate cellular reproduction is the relative biological effectiveness (RBE). A quality related to the RBE that is a measurable physical property is the linear energy transfer …

Hsc Committee Minutes 09-05-2017, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

11-07-2017 Hsc Committee Agenda, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Associations Between Medical Cannabis And Prescription Opioid Use In Chronic Pain Patients: A Preliminary Cohort Study [Dataset], Jacob M. Vigil, Sarah S. Stith, Ian M. Adams, Anthony P. Reeve

Psychology Datasets

No abstract provided.

11-07-2017 Hsc Committee Meeting Notice, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

A Socio-Ecological Analysis Of Childhood Obesity And School Nutrition Policies And Practices In Select Elementary And Middle Schools On The Navajo Reservation, Regina S. Eddie

Nursing ETDs

Navajo and other American Indian children are most affected by overweight and obesity in comparison to their US counterparts, and schools have become a focal setting for prevention interventions. The study applied an ecological and a cultural framework to analyze the various factors that influence the food choices available to students and the impact of these choices on childhood obesity. The overall purpose of this descriptive study was to examine and describe how schools that participate in the National School Lunch Program (NSLP) are contributing to the diets of Navajo students since the passage of the Healthy Hunger Free Kids …

10-10-2017 Hsc Committee Meeting Cancellation Notice, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

10-10-2017 Hsc Committee Agenda, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Mathematical Modeling For Predicting Chemotherapy And Nanoparticle Treatment Efficacy In Breast Cancer, Terisse Arielle Brocato

Biomedical Engineering ETDs

Breast cancer treatment response varies by subtype, treatment regiment, and additionally by vasculature characteristics. For this reason, breast cancer is a model disease for the development of both targeted therapy and prognostic and predictive biomarkers. Mathematical modeling allows for personalized patient specific prediction of treatment outcome based on parameters found to be important to the cancer type. Mathematical modeling is beneficial in providing insight into why cancer treatment fails and in what cases, additionally determining what characteristics result in a successful treatment. Presented in Chapter 1 is a scientific introduction and discussion focusing on representative modeling works specified towards breast …

Elearning For Medical Educators (Elme): Pod Network 2016 Educational Development Internship Program, Gary A. Smith, Audriana Stark

Office for Medical Educator Development (OMED)

eLearning for Medical Educators (eLME) is under development as a mechanism to provide professional learning in medical education to anyone, anytime, anywhere. The project began in 2016 at the Office for Medical Educator Development within the UNM School of Medicine in order to support community faculty who host medical students and residents at their clinics. eLME was planned with numerous stakeholders using the Kirkpatrick Business Partnership Model. Two modules were delivered in early 2017 and include a combination of self-reflection, interactive multimedia, and assessment.

A Retinal Vessel Detection Approach Based On Shearlet Transform And Indeterminacy Filtering On Fundus Images, Florentin Smarandache, Yanhui Guo, Umit Budak, Abdulkadir Sengur

Branch Mathematics and Statistics Faculty and Staff Publications

A fundus image is an effective tool for ophthalmologists studying eye diseases. Retinal vessel detection is a significant task in the identification of retinal disease regions. This study presents a retinal vessel detection approach using shearlet transform and indeterminacy filtering. The fundus image’s green channel is mapped in the neutrosophic domain via shearlet transform. The neutrosophic domain images are then filtered with an indeterminacy filter to reduce the indeterminacy information. A neural network classifier is employed to identify the pixels whose inputs are the features in neutrosophic images. The proposed approach is tested on two datasets, and a receiver operating …

Adobe Medicus 2017 5 September-October, Health Sciences Library And Informatics Center

adobe medicus

The bimonthly newsletter published by UNM's Health Sciences Library and Informatics Center, adobe medicus announces new programs, services and activities at the library and at the UNM Health Sciences Center. It also reports on recent activities, events and awards associated with the library and includes articles about services that patrons may not be aware of.

Patient Centered Family Planning Care, Lauren Thaxton Md, Mba

Biomedical Sciences ETDs

The Institute of Medicine defines six important domains of health care quality: safety, efficacy, timeliness, efficiency, equitable delivery and patient-centeredness. Quality family planning care aims to provide individuals with the tools needed to engage in healthy and satisfying sex lives while planning and spacing pregnancies to achieve desired family size. The field of family planning strongly relies on the domain of patient-centeredness as individual values and preferences guide clinical care. Yet large gaps in knowledge exist in understanding how to improve patients’ clinical experience. This hybrid thesis posits avenues for improving the quality and patient-centeredness of clinical care.

Quality care …

Revised 10-10-2017 Hsc Committee Notice Of Meeting, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Exploring Biological Heterogeneity And Its Consequences At Tissue And Cellular Scales Through Mathematical And Computational Modeling, Romica Kerketta

Biomedical Sciences ETDs

This dissertation explores the effects of heterogeneity across different biological scales in cancer as well as normal cells. At the tissue scale, we investigated the variability present in the tumor microenvironment and its effect on patient chemotherapeutic outcomes using a mathematical model of drug transport. We found that parameters such as tumor blood perfusion and radius of blood vessel had an impact on the tumor cytotoxicity. This indicated that the physical microenvironment of the tumor is an important regulator of the tumor response to chemotherapy. At the cellular scale, we investigated the heterogeneity present on the membrane landscape of ErbB2 …

10-10-2017 Notice Of Hsc Committee Meeting, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Hsc Committee Meeting Minutes August 8 2017, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Web Resources For Physician Wellness, Elizabeth C. Lawrence

Office of Physician and Student Wellness (OPSW)

A current listing of websites, TED talks, and podcasts related to physician wellness and resiliency.

Photography And Catalogue Of Cutaneous Vascular Malformations Of Patients With Ccm1- Chm Cerebral Cavernous Malformations, Athanasios K. Manole

Biomedical Sciences ETDs

Due to a genetic mutation, a rare and potentially fatal disease has spread throughout New Mexico. This disease, Familial Cerebral Cavernous Malformation (FCCM1-CHM), is due to a mutation that affects peoples of Hispanic heritage in New Mexico. The FCCM disease is characterized by the development of dilated, thin walled, leaky vessels that occur in the brain and spinal cord. As a result of this genetic mutation, the lesions in the blood vessels of the brain and spinal cord are highly susceptible to hemorrhaging into surrounding tissue. This can lead to headaches, seizure, and possibly death. Researchers at the University of …