Medicine and Health Sciences Commons^™

Findings Of Cognitive Impairment At High Altitude: Relationships To Acetazolamide Use And Acute Mountain Sickness., Lara Phillips, Buddha Basnyat, Yuchiao Chang, Erik R. Swenson, N. Stuart Harris

Department of Emergency Medicine Faculty Papers

Phillips, Lara, Buddha Basnyat, Yuchiao Chang, Erik R. Swenson, and N. Stuart Harris. Findings of cognitive impairment at high altitude: relationships to acetazolamide use and acute mountain sickness. High Alt Med Biol. 18:121-127, 2017.

OBJECTIVE: Acute mountain sickness (AMS) is defined by patient-reported symptoms using the Lake Louise Score (LLS), which provides limited insight into any possible underlying central nervous system (CNS) dysfunction. Some evidence suggests AMS might coexist with altered neural functioning. Cognitive impairment (CI) may go undetected unless a sensitive test is applied. Our hypothesis was that a standardized test for mild CI would provide an objective measure …

Critical Care Nurses' Experiences Of Family Behaviors As Obstacles In End-Of-Life Care, Caitlin Brook Mallory

Theses and Dissertations

Background: Critical care nurses (CCNs) frequently provide end-of-life care for critically ill patients. CCNs may face many obstacles while trying to provide quality EOL care. Some research focusing on obstacles CCNs face while trying to provide quality EOL care has been published; however, research focusing on family behavior obstacles is limited. Research focusing on family behavior as an EOL care obstacle may provide additional insight and improvement in care. Objective: What are the predominant themes noted when CCNs share their experiences of common obstacles, relating to families in providing EOL care? Methods: A random geographically dispersed sample of 2,000 members …

Outcomes Of Spatially Fractionated Radiotherapy (Grid) For Bulky Soft Tissue Sarcomas In A Large Animal Model, Michael W. Nolan, Tracy L. Gieger, Alexander A. Karakashian, Mariana N. Nikolova‑Karakashian, Lysa P. Posner, Donald M. Roback, Judith N. Rivera, Sha Chang

Physiology Faculty Publications

GRID directs alternating regions of high- and low-dose radiation at tumors. A large animal model mimicking the geometries of human treatments is needed to complement existing rodent systems (eg, microbeam) and clarify the physical and biological attributes of GRID. A pilot study was undertaken in pet dogs with spontaneous soft tissue sarcomas to characterize responses to GRID. Subjects were treated with either 20 Gy (3 dogs) or 25 Gy (3 dogs), delivered using 6 MV X-rays and a commercial GRID collimator. Acute toxicity and tumor responses were assessed 2, 4, and 6 weeks later. Acute Radiation Therapy Oncology Group grade …

Quantifying Lingua-Palatal Contact Patterns Of Fricative Productions By Non-Native Students Enrolled In A University German Language Course: An Electropalatography Study, Kate Erin Lester

Theses and Dissertations

Electropalatography (EPG) is a computer-based tracking system designed to provide real-time visual biofeedback of articulatory contacts occurring during speech production. Historically, EPG technology has proven functional within the treatment and assessment of speech disorders however, application of EPG technology to assist in second language learning has remained limited. The present thesis is part of a larger study examining the effectiveness of using EPG as an advanced instructional tool for assisting second language (L2) learners of German. Fricative productions ([ç], [x], /s/, and /∫/) within real words were gathered from 12 native English speakers enrolled in a second semester university level …

Using A Social Communication Intervention To Increase Emotion Word Use In Children With Language Impairment, Breeana Lee Bell

Theses and Dissertations

The purpose of this thesis was to evaluate the efficacy of an intervention to increase the production of emotion words in five children with language impairment. Participants were between the ages of 5;11 (years; months) and 11;3 (at the onset of enrollment in treatment) and had been identified with language impairment. Each participant completed between three and six baseline sessions, 20 twenty-minute intervention sessions, and three follow-up sessions. Tasks included story reading, story enactment, and journaling. Each session was recorded and then coded for emotion category (sadness, anger, fear, and surprise), errors made, type of production, and valence agreement. Total …

Perceptual Analysis Of Children's Adaptation To An Electropalatography Sensor, Kasey Marie Duffield

Theses and Dissertations

The purpose of this study is to observe childrens adaptation to an electropalatographic (EPG) sensor. Sound recordings of six children between the ages of 7;0 and 9;11 sampled at 30-minute intervals over a two-hour period of wearing an EPG sensor were perceptually evaluated to quantify the children's adaptation over time. Twenty native speakers of American English evaluated the pronunciation of a series of words with embedded stops and fricatives produced with and without an EPG sensor in place. When collapsed over speaker and stimulus type, listener ratings decreased significantly after inserting the EPG sensor. Ratings then increased significantly after the …

Physiological Attunement And Influence In Couples Therapy: Examining The Roots Of Therapeutic Presence, Julia Campbell Bernards

Theses and Dissertations

Extensive interdisciplinary common factor research has identified the therapeutic relationship as a consistent factor influencing therapeutic outcomes. We use Polyvagal and Interpersonal Neurobiology (IPNB) theories to guide an examination of the physiological mechanisms at work in the therapeutic relationship. Both Polyvagal and IPNB theories provide understandings about how humans are neurophysiologically wired for social connection. Each points to a sense of safety as being essential for meaningful connection to occur and clarifies that physiological attunement is an observable indicator of interpersonal connection. In this study, we use these theories to guide an examination of therapist physiological influence on clients in …

Medical Pluralism, Regulations And Pharmacopoeia: A Perspective, Raj Manchanda

Indian Journal of Research in Homoeopathy

No abstract provided.

Phytochemical Analysis And Evaluation Of Antioxidant Potential Of Ethanol Extract Of Allium Cepa And Ultra-High Homoeopathic Dilutions Available In The Market: A Comparative Study, Ekta Arora, Vibha Sharma, Anil Khurana, Ananya Manchanda, Dilsheen Sahani, Sijo Abraham, Deepa Kundu, Himani Gupta, Lunthanglien Chiru

Indian Journal of Research in Homoeopathy

Introduction: As per statistics available with the WHO, 80% of the earth's population rely on traditional medicine for their primary health-care needs and most of this therapy involves the use of plant extracts and their active components. Objectives: To confirm the presence of alkaloids, fats, steroids, tannins, flavonoids, sugars, amino acids and saponins in Allium cepa extract. Method: A qualitative phytochemical analysis has been performed to confirm the presence of these components in Allium cepa extract and its homoeopathic formulations (mother tincture [MT], Allium cepa 30C and Allium cepa 200C). The total phenolic content, flavonoid content and antioxidant potential of …

Homoeopathic Pathogenetic Trial Of Withania Somnifera: A Multicentric, Double-Blind, Randomised, Placebo-Controlled Trial, Pritha Mehra, Anil Khurana, Renu Mittal, Bhopal Arya, Rajpal Rajpal, Raj Manchanda, Karuna Singh, Anil Vichitra, Goutam Rakshit

Indian Journal of Research in Homoeopathy

Background: Homoeopathic drug proving being the first step in finding the pathogenetic powers of a drug is an integral part of Homoeopathic system of medicine. Objective: To elicit the pathogenetic response of Withania somnifera in homoeopathic potencies on healthy human provers. Materials and Methods: A multicentre, randomised, double-blind, placebo-controlled trial was conducted at four centres under Central Council for Research in Homoeopathy. Proving was conducted on 63 relatively healthy provers. All the provers were given 12 doses of placebo divided into 4 doses/day for 3 days during the first phase of the trial. After randomisation, 43 provers in the intervention …

Medical Pluralism In Europe And India: Concept, Historical Background, Perspectives, Martin Dinges

Indian Journal of Research in Homoeopathy

No abstract provided.

A Practical Handbook Of Homeopathic Immunisation (The Complete Practitioner's Manual Of Homoeoprophylaxis), Kanjaksha Ghosh

Indian Journal of Research in Homoeopathy

No abstract provided.

Standing On The Shoulders Of Giants: Review Of Ccrh Quarterly Bulletin 2004 (Volume 26) And 2005 (Volume 27), Shashi Giri

Indian Journal of Research in Homoeopathy

No abstract provided.

Research Highlights (April–June 2017), Reteka Sexena

Indian Journal of Research in Homoeopathy

No abstract provided.

Brief Report: Medication Sharing Is Rare Among African Hiv-1 Serodiscordant Couples Enrolled In An Efficacy Trial Of Oral Pre-Exposure Prophylaxis (Prep) For Hiv-1 Prevention, Kerry A. Thomson, Jessica Haberer, Mark A. Marzinke, Andrew Mujugira, Craig Hendrix, Connie Celum, Patrick Ndase, Alan Ronald, David Bangsberg, Jared Baeten

OHSU-PSU School of Public Health Faculty Publications and Presentations

Sharing of pre-exposure prophylaxis (PrEP) medications is a concern for PrEP implementation. For HIV-1 serodiscordant couples, sharing may undermine the HIV-1 prevention benefit and also cause antiretroviral resistance if taken by HIV-1 infected partners. Within a PrEP efficacy trial among HIV-1 serodiscordant couples, we assessed the occurrence of PrEP sharing by self-report and plasma tenofovir concentrations in HIV-1 infected partners. PrEP sharing was self-reported at < 0.01% of visits, and 0% -1.6% of randomly selected and 0% of purposively selected specimens from HIV-1 infected participants had detectable tenofovir concentrations (median: 66.5 ng/mL, range: 1.3-292 ng/mL). PrEP sharing within HIV-1 serodiscordant couples was extremely rare.

Jaw Rotation In Dysarthria Measured With A Single Electromagnetic Articulography Sensor, Jeffrey J. Berry, Andrew Kolb, James Schroeder, Michael T. Johnson

Speech Pathology and Audiology Faculty Research and Publications

Purpose This study evaluated a novel method for characterizing jaw rotation using orientation data from a single electromagnetic articulography sensor. This method was optimized for clinical application, and a preliminary examination of clinical feasibility and value was undertaken.

Method The computational adequacy of the single-sensor orientation method was evaluated through comparisons of jaw-rotation histories calculated from dual-sensor positional data for 16 typical talkers. The clinical feasibility and potential value of single-sensor jaw rotation were assessed through comparisons of 7 talkers with dysarthria and 19 typical talkers in connected speech.

Results The single-sensor orientation method allowed faster and safer participant preparation, …

Five-Year Follow-Up Of A Coronally Advanced Flap Over Grafted Bone And Restorative Composite In Maxillary Recession Defect., Syeda Mahvash Hussain, Farhan Raza Khan

Section of Dental-Oral Maxillofacial Surgery

Periodontal plastic surgery has become a predictable method of managing gingival recession defects. In the current case report, a five-year follow-up of a coronally advanced flap surgery with bone graft along with endodontics and fixed prosthodontic rehabilitation is reported in the maxillary anterior sextant of a middle aged female. The present case demonstrates that deep and wide gingival defects can be treated with coronally positioned surgical flap without a connective tissue graft. Amultidisciplinary management approach was adopted in this case that yielded predictable outcome.

Diverse Expression Patterns And Tumorigenic Role Of Neurotensin Signaling Components In Colorectal Cancer Cells, Ji Tae Kim, Heidi L. Weiss, B. Mark Evers

Markey Cancer Center Faculty Publications

Colorectal cancer (CRC), which is one of the most common malignancies worldwide, results from an accumulation of genetic and epigenetic modifications including DNA methylation. Neurotensin (NTS), a hormone localized to the gut and central nervous system, mediates its physiological and pathological effects, including growth stimulation for a variety of cancers, through three distinct NTS receptors (NTSRs). Most NTS functions are mediated through the high-affinity receptor NTSR1, and expression of NTSR1 is increased in many cancers including CRC. In this study, we investigated the expression profiles and cellular functions of the NTSRs, especially NTSR1, in CRC cells. We showed that expression …

Understanding The Link Between Substance Abuse And Mental Health, Crystal Ann Horton

Electronic Theses, Projects, and Dissertations

Treating people with co-occurring or dual diagnosis disorders requires an integrated treatment approach due to the complex health and social needs of people who suffer from mental illness and drug addiction. An integrated approach is not only necessary but crucial to treat both the drug addiction and mental illness concurrently. The aim of this study is to explore the impact that non- integrated care can have on the number of relapses that dually diagnosed people can have. The study found that there is no correlation between concurrent treatment and the number of relapses that dually diagnosed people may have. Social …

Clinical Social Workers’ Perspectives On Illicit Drug Use And The Development Of Psychotic Disorders, Asma Naseer

Electronic Theses, Projects, and Dissertations

This purpose of this study was to explore social workers’ perspectives of drug-induced psychosis. More specifically, it sought to determine how knowledgeable clinical social workers are on the impact illicit drug use on the development of psychotic disorders. The study also aimed to discover clinical social workers’ perspectives regarding the influence of illicit drug use on the development of psychotic illnesses. This study used mixed methods approach in attempt to solve the research question. The quantitative portion of the research, an anonymous survey, allowed for the assessment of social workers’ knowledge of drug-induced psychosis. The qualitative portion of the research, …

Exploring The Relationship Between Occupational Burnout And The Behavioral Well-Being Of Social Workers, Damian A. Pisapia

Electronic Theses, Projects, and Dissertations

The purpose of this study was to determine if there was a relationship between occupational burnout and the behavioral well-being of social workers. Burnout is a multidimensional syndrome where workers experience feelings of emotional exhaustion, depersonalization, and reduced personal accomplishment as a consequence of work related stress and overwhelming job demands. Burnout can negatively affect organizational functioning, work performance, and pose significant health risks to workers. There are a limited number of studies focusing on the impact of occupational burnout on the behavioral well-being of workers. The findings of this study indicated that there was a significant relationship between burnout …

Primary Lung Carcinoid Metastatic To The Breast, Marianna Zagurovskaya, Karen Tran-Harding, Richard Gibbs

Radiology Faculty Publications

Lung carcinoid tumors account for approximately 2% of lung cancers, with 10% of the tumors represented by the atypical type. While atypical carcinoids are metastatic to intrathoracic lymph nodes in approximately half of the cases on the initial presentation, distant metastases are seen in only 20% of the patients and are found most frequently in bones, liver, adrenal glands, and brain. We present a case of an unusual metastatic disease to the breast in 51-year-old female who developed a new breast mass 2 years after left lower lobectomy due to atypical carcinoid tumor. Atypical pulmonary carcinoid metastases to the breast …

Towards Unobtrusive Mental Well-Being Monitoring For Independent-Living Elderly, Sinh Huynh, Hwee-Pink Tan, Youngki Lee

Research Collection School Of Computing and Information Systems

It is essential to proactively detect mental health problems such as loneliness and depression in the independently-living elderly for timely intervention by caregivers. In this paper, we introduce an unobtrusive sensor-enabled monitoring system that has been deployed to 50 government housing ats with the independent-living elderly for two years. Then, we also present our initial findings from the 6-month sensor data between August 2015 and April 2016 as well as the survey data to measure the subjective well-being indicator. Our study showed the promising results that "room-level movements within a house" and "going out" behavior captured by our simple sensor …

Sensation Seeking Impact On Skin Conductance Measures Of Deception And Memory, Andrew David Manson, Suzanna Lagerroos, Phillip Janz, Adam Lawson, Jonathan Gore

EKU Faculty and Staff Scholarship

We sought to determine whether sensation seeking would differentially predict measures of memory and deception (concealing information) as indexed by behavioral (response time, accuracy) and autonomic (skin conductance level) markers in a sample of college students. Participants were randomly assigned to a mock-crime group or an innocent-errand group. Both groups were trained to complete a task requiring the copying of documents from a secure location; the difference was the mock-crime group broke into the office whereas the errand group was given permission to enter the room and access the documents. After being trained to perform the crime or errand task, …

Determination Of Age And Construction Of Population Age Structure Of Wild Asian Elephants Based On Dung Bolus Circumference, Chalita Kongrit, Chomcheun Siripunkaw

The Thai Journal of Veterinary Medicine

Estimating the age of wildlife is an important technique for the construction of a population age structure that could be useful for the prediction of population change. The age of wild elephants can be reliably estimated from the size of dung bolus circumference which correlates with elephant growth. This research aimed to determine a cut-off bolus circumference for the mature age class of wild Asian elephants at Salakphra Wildlife Sanctuary as inferred from the social behavior of male elephants. Males living within their natal groups were considered immature males, whereas solitary males were considered mature males. The largest bolus circumference …

What Is Your Diagnosis?, Chutimon Thanaboonnipat, Nan Choisunirachon

The Thai Journal of Veterinary Medicine

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Effects Of Cryopreservation And Leukodepletion On Morphological Index Of Red Blood Cells In Dogs, Deniz Aktaran Bala, Ibrahim Akyazi

The Thai Journal of Veterinary Medicine

Preservation of blood components for transfusion is a long-standing phenomenon. However, studies of cryopreservation of leukodepleted canine erythrocytes are quite limited and no studies are available with respect to morphological evaluation of erythrocytes during the cryopreservation process. The aim of this study was to determine morphological changes caused by cryopreservation, storage and leukocyte filtration. Healthy adult dogs meeting the criteria for blood transfusion were used in this study. Packed red blood cells (pRBCs) were obtained from each dog. The samples were divided into two groups. Leukocyte filtration was performed on one group of pRBCs. The other group received no filtration. …

Development Of Indirect Enzyme-Linked Immunosorbent Assay For Antibody Detection Against Avibacterium Paragallinarum, Panchita Hongprasertkul, Wisanu Wanasawaeng, Niwat Chansiripornchai

The Thai Journal of Veterinary Medicine

Indirect enzyme-linked immunosorbent assay (I-ELISA) for antibody detection against A. paragallinarum serovars A, B and C was developed in separated plates. One hundred Babcock 308 female layer chickens were randomly divided into five groups of 20 each. Groups 1, 2, 3 and 4 were different positive control groups of immunized chickens with commercial trivalent mineral oil vaccine, and prepared bacterins of Avibacterium paragallinarum serovars A (221), B (0222) and C (Modesto), respectively. The chickens in Group 5 were assigned as a negative control. Positive and negative control sera from the chickens in Groups 1-5 at 2 weeks after the second …

Effects Of Chikungunya Virus Titers In Blood Meals On Virus Infection, Dissemination, And Transmission In Asian Tiger Mosquito: Aedes Albopictus (Diptera: Culicidae), Ranida Tuanudom, Nichapat Yurayart, Sonthaya Tiawsirisup

The Thai Journal of Veterinary Medicine

Chikungunya virus (CHIKV) is an important mosquito-borne virus and transmission cycle of this virus involves mosquito vectors and infected vertebrate hosts. However, the study about vector competence for CHIKV in Thailand is limited. This study was conducted to examine the effects of CHIKV titers in blood meals on vector competence of Aedes albopictus (Diptera: Culicidae). Five groups of Ae. albopictus were allowed to feed on different levels of CHIKV in the blood meals which were 102, 103, 104, 105, and 106 CID50/ml of CHIKV. Body, legs and wings, and saliva samples from blood-fed mosquitoes were assayed for the presence of …

Ecg Quiz, Chollada Buranakarl, Saikaew Sutayatram

The Thai Journal of Veterinary Medicine

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