Medicine and Health Sciences Commons^™

Protective Factors Against Peer And Social Media Sex Messages: The Moderating Role Of Parental Influences On African American Emerging Adult Students' Sexual Behaviors, Jacqueline Eunice Haywood

Psychology Theses & Dissertations

The most recent research on risky sexual behaviors is primarily based on adolescent, predominately White, or multiple race (e.g., African American and White) samples. There is a paucity of literature focused exclusively on African Americans, particularly African American emerging adults between the ages of 18 and 25. Given the increased risk for sexually transmitted infections (STIs) for college aged African Americans, it is important to understand factors that may decrease engaging in risky sexual behaviors that are specific to this group. The current study examined the roles of parental warmth and communication about sex as protective factors. Participants (n = …

Spinal Cord Compression Secondary To Metastatic Sinonasal Undifferentiated Carcinoma, Arthur Wang, J Wainwright, Anubhav Amin, Eric Vail, R Silverstein, Kaushik Das

NYMC Faculty Publications

Sinonasal undifferentiated carcinoma (SNUC) is a rare malignancy of the upper airways and anterior skull base that carries a poor prognosis. The tumor is known to be invasive into the surrounding structures of the skull base and brain. To date, there is only one existing case report documenting drop metastasis to the intradural extramedullary spinal cord. To the best of our knowledge, we present the second case of metastatic SNUC to the spine. This report describes a 59-year-old male with a history of head and neck SNUC who presented with thoracic back pain and bilateral lower extremity paresis. Neuroimaging demonstrated …

Cardiovascular Benefits Of The Newer Medications For Treating Type 2 Diabetes Mellitus, Srikanth Yandrapalli, Wilbert Aronow

NYMC Faculty Publications

Diabetes mellitus is growing in pandemic proportions and is associated with significant morbidity, mortality, and health care expenditure. Type 2 diabetes mellitus (T2DM) is the most common, accounting for about 90-95% of diagnosed diabetes in United States adults. Individuals with T2DM have a 2- to 3-fold increased risk of cardiovascular (CV) events compared with their non-diabetic counterparts, and CV mortality is responsible for around 80% of the mortality in T2DM. Emerging evidence suggest that in T2DM patients, hyperglycemia plays a little role in the progression of CV disease, and metabolic risk factors like insulin resistance, hypertension, obesity, and dyslipidemia are …

Evaluating The Relationship Between Participation In Student-Run Free Clinics And Changes In Empathy In Medical Students., Anita Modi, Michele Fascelli, Zachary Daitch, Mohammadreza Hojat Professor

Department of Medicine Faculty Papers

PURPOSE: We explored differences in changes in medical student empathy in the third year of medical school between volunteers at JeffHOPE, a multisite medical student-run free clinic of Sidney Kimmel Medical College (SKMC), and nonvolunteers.

METHOD: Volunteerism and leadership experience at JeffHOPE were documented for medical students in the Class of 2015 (n = 272) across their medical educations. Students completed the Jefferson Scale of Empathy at the beginning of medical school and at the end of the third year. Students who reported participation in other Jefferson-affiliated clinics (n = 44) were excluded from this study. Complete data were available …

Comparison Of Two Nicotine Dependence Measures For Use With Korean American Women: The Ftnd And Autos, Sun S. Kim Phd, Aprn-Bc

Asian/Pacific Island Nursing Journal

This study compares psychometric properties of the Fagerström Test for Nicotine Dependence (FTND) and Autonomy over Tobacco Scale (AUTOS), which are measures of nicotine dependence. This study is a secondary analysis of data obtained from a smoking cessation study conducted with 49 Korean American women. We compared the FTND and AUTOS assessed at baseline regarding their internal consistency reliability and concurrent and predictive validities. The AUTOS outperformed the FTND in reliability and concurrent validity by yielding a higher Cronbach’s alpha and having significant relationships with smoking-related variables such as age at smoking onset, perceived risks of quitting, and self-efficacy in …

Study Of Nurses' Attitudes And Practices Towards Pain Evaluation In Nonverbal Patients, Rebekah Lovin

Montview Journal of Research & Scholarship

Pain, and the appropriate treatment of it, has recently come to the forefront of issues addressed with healthcare providers. Since the cornerstone of pain management is an appropriate assessment, methods of accurate pain evaluation are necessary. This need is particularly important in the population of patients who cannot express their pain. While pain assessment tools are available for use with nonverbal patients and hospitals typically mandate the use of one of these tools, actual compliance with such policy may not actually occur. Various barriers, such as education in the use of a tool, time, and the personal views of the …

The Effect Of Barefoot Running Using Two Running Styles On Lower Extremity Joint Reaction Forces, Jamie M. Rogers Ep-C

Montview Journal of Research & Scholarship

Running is a popular worldwide activity with many varying biomechanical techniques. Investigating potential differences in joint forces can be beneficial in determining if there is a superior biomechanical running pattern. Previous research compared barefoot and shod running, as well as the kinetic effects of varied running styles. The current study investigated the differences in internal joint reaction forces (JRF) at the hip, knee, and ankle joints during running with two different styles. Ten male and ten female participants who naturally run with a rearfoot strike pattern were included in this study. Each subject ran barefoot on an instrumented treadmill for …

Reducing Antibiotic Use In Pediatric Upper Respiratory Infection: A Multifaceted Parent-Clinician Approach, Sydnee H. Lucas Dnp, Aprn, Sydney Thompson Dnp, Arnp, Fnp-Bc

Journal of Nursing & Interprofessional Leadership in Quality & Safety

The goal of this QI initiative was to decrease inappropriate antibiotic for the treatment of pediatric upper respiratory infection (URI) in the retail clinic setting. The approach included the use of a protocol to treat viral upper respiratory illness, a visual aid decision-making tool for guideline adherence, prescription pad for nonprescription remedies, and shared decision-making techniques for providers to involve patients and parents in management plans regarding nonprescription remedies, supportive treatment, and signs and symptoms that would warrant a return visit. An improvement trend during the first 3 months of the initiative showed a shift in antibiotic avoidance from a …

Reducing Medication Errors Through Workflow Redesign, Rosslyn W. Blake Dnp, Aprn, Gnp

Journal of Nursing & Interprofessional Leadership in Quality & Safety

Lack of medication reconciliation at the point of transitions between skilled nursing facilities/nursing homes (SNF/NHs) and acute care hospitals (ACHs) is a common point of origin for medical errors that cause harm to patients. The goal of this quality improvement initiative was to improve medication reconciliation at the point of transition from the SNF/NH to the ACH which in turn would reduce medication errors, adverse drug events, and medication-induced injury to the vulnerable elderly population. We implemented a workflow redesign process to reconcile the accuracy of residents’ medications at the time of transfer from the SNF/NH to the ACH. After …

Using Business Modeling To Streamline Cost Of Anesthesia In A Cardiopulmonary Laboratory, Johnny Dang Dnp, Crna, Kristen Starnes-Ott Phd, Crna

Journal of Nursing & Interprofessional Leadership in Quality & Safety

The Time Driven Activity Based Costing (TDABC) measurement system, a model used in the business arena, can capture clinical processes and costs that other costing models often overlook. Use of this system permitted tying costs to time and resources and identified areas of inefficiency such as depleted supplies and health care and emergency supplies placed inconveniently. A multidisciplinary team developed an anesthesia checklist for use in a remote cardiopulmonary laboratory. The compliance rate for checklist completion was approximately 85%. Checklist implementation translated to a decrease in case delays and time expenditure in patient care by 58% with a cost savings …

The Impact Of Dysphagia On Quality Of Life And Stigma In Hispanic New Mexicans, Aaron Padilla

Speech and Hearing Sciences ETDs

INTRODUCTION: Eating is a function of daily life and is the centerpiece of family gatherings, business meetings, and holiday/religious traditions. Dysphagia (difficulty swallowing), can abolish the pleasure of mealtimes, which can negatively impact quality of life (QOL) and result in stigma. These variables may be influenced by cultural perceptions and/or acculturation, which is a measure of the impact that one cultural group has on another. The purpose of this investigation was to: a) identify the relationship between level of acculturation and QOL and stigma for Hispanics, b) measure the relationship between dysphagia severity and QOL and stigma, and c) explore …

Alternative Splicing Promotes Tumour Aggressiveness And Drug Resistance In African American Prostate Cancer., Bi-Dar Wang, Kristin Ceniccola, Sujin Hwang, Ramez Andrawis, Anelia Horvath, Jennifer A Freedman, Jacqueline Olender, Stefan Knapp, Travers Ching, Lana Garmire, Vyomesh Patel, Mariano A Garcia-Blanco, Steven R Patierno, Norman H Lee

Pharmacology and Physiology Faculty Publications

linical challenges exist in reducing prostate cancer (PCa) disparities. The RNA splicing landscape of PCa across racial populations has not been fully explored as a potential molecular mechanism contributing to race-related tumour aggressiveness. Here, we identify novel genome-wide, race-specific RNA splicing events as critical drivers of PCa aggressiveness and therapeutic resistance in African American (AA) men. AA-enriched splice variants of PIK3CD, FGFR3, TSC2 and RASGRP2 contribute to greater oncogenic potential compared with corresponding European American (EA)-expressing variants. Ectopic overexpression of the newly cloned AA-enriched variant, PIK3CD-S, in EA PCa cell lines enhances AKT/mTOR signalling and increases proliferative …

The Specific Vulnerabilities Of Cancer Cells To The Cold Atmospheric Plasma-Stimulated Solutions., Dayun Yan, Haitao Cui, Wei Zhu, Niki Nourmohammadi, Julian Milberg, Lijie G Zhang, Jonathan H Sherman, Michael Keidar

Neurological Surgery Faculty Publications

Cold atmospheric plasma (CAP), a novel promising anti-cancer modality, has shown its selective anti-cancer capacity on dozens of cancer cell lines in vitro and on subcutaneous xenograft tumors in mice. Over the past five years, the CAP-stimulated solutions (PSS) have also shown their selective anti-cancer effect over different cancers in vitro and in vivo. The solutions used to make PSS include several bio-adaptable solutions, mainly cell culture medium and simple buffered solutions. Both the CAP-stimulated medium (PSM) and the CAP-stimulated buffered solution (PSB) are able to significantly kill cancer cells in vitro. In this study, we systematically compared the anti-cancer …

Animal Models Of Rheumatoid Pain: Experimental Systems And Insights., Bradford D Fischer, Adeshina Adeyemo, Michael E O'Leary, Andrea Bottaro

Cooper Medical School of Rowan University Departmental Research

Severe chronic pain is one of the hallmarks and most debilitating manifestations of inflammatory arthritis. It represents a significant problem in the clinical management of patients with common chronic inflammatory joint conditions such as rheumatoid arthritis, psoriatic arthritis and spondyloarthropathies. The functional links between peripheral inflammatory signals and the establishment of the neuroadaptive mechanisms acting in nociceptors and in the central nervous system in the establishment of chronic and neuropathic pain are still poorly understood, representing an area of intense study and translational priority. Several well-established inducible and spontaneous animal models are available to study the onset, progression and chronicization …

2016-2017 Department Of Psychiatry And Behavioral Sciences Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

2016-2017 Department Of Surgery Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

2016-2017 Department Of Pathology Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

2016-2017 Department Of Learning Resources Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

2016-2017 Department Of Internal Medicine Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

2016-2017 Department Of Family Medicine Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

2016-2017 Department Of Obstetrics And Gynecology Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

2016-2017 Department Of Biomedical Sciences Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

The Association Between Elevated Levels Of Erythropoietin Andendothelial Progenitor Cell With Improvement Of Endothelialfunction In Renal Failure Patients 3 Months After Kidneytransplantation, Linda Armelia, Endang Susalit, Maruhum Bonar Hm, Hamzah Shatri

Jurnal Penyakit Dalam Indonesia

Introduction. Endothelial progenitor cell (EPC) is considered possible to reduce asymmetric dimethylarginine (ADMA) levels, which is a marker of improved endothelial function. However, clinically, there is still a debate about the role of EPC. This study was conducted to determine the correlation of elevated levels of erythropoietin (Epo) and the number of EPC CD34 + and CD133 + with improvement of endothelial function in renal failure patients 3 months after kidney transplantation. Methods. A cross-sectional study was conducted in prior and 3 months after kidney transplantation of renal failure patients who underwent a kidney transplant in Cipto Mangunkusumo hospital. The …

The Changes Of Amino Terminal Pro B-Type Natriuretic Peptide(Nt-Probnp) Concentration And Left Ventricular Ejectionfraction On Doxorubicin Chemotherapy Patients, Telly Kamelia, Sarwono Waspadji, Lukman Hakim Makmun, Shufrie Effendi, Muchlis Ramli, Ina Susanti Timan

Jurnal Penyakit Dalam Indonesia

Introduction. Cancer patients who received chemotherapy regimen containing doxorubicin has been known to have serious side effect in heart, called as cardiotoxicity. The measurement of NT-proBNP proposed to be used as a new parameter to identify and evaluate cardiotoxicity in cancer patients earlier before it has been manifested, superior than measurement of left ventricle ejection fraction (LVEF). The aims of this study to examine the changes of NT-proBNP concentration and LVEF on patients with cancer who receive chemotherapy regimen containing doxorubicin. Methods. The study used pre and post test design to observe the changes of NT-proBNP concentration and LVEF on …

Validation Of Rapid Emergency Medicine Score (Rems) In Predicting30 Days Mortality In Elderly Visiting Emergency Department, Aulia Rizka, Kuntjoro Harimurti, Ceva W. Pitoyo, Soekamto Koesno

Jurnal Penyakit Dalam Indonesia

Introduction. Rapid Emergency Medicine Score (REMS) has been known as a useful instrument to stratify patients in emergency department (ED) based on its ability to predict short term mortality. As the clinical characteristics of elderly patients visiting ED are frequently aypical, validation of REMS in this specific population is very important. To measure predictive validity of REMS in elderly patients visiting ED Methods. Prospective cohort study in elderly visiting ED of Cipto Mangunkusumo between September to October 2016. Subjects were followed for 30 days after visiting ED. Calibration (Hosmer Lemeshow test), discrimination (Area Under ROC Curve) and REMS predictive value …

Factors Associated With Retention In Care One Year After Deliveryin Patients Undergoing Prevention Of Mother To Child Transmission(Pmtct) At Rscm, Yulidar Yulidar, Evy Yunihastuti, Samsuridjal Djauzi, Astrid Citra Padmita, Sukamto Koesnoe

Jurnal Penyakit Dalam Indonesia

Introduction. Retention in care is important to the successful of HIV treatment. This study is aimed to analyze factors associated with retention in care one year after delivery in patients undergoing PMTCT at HIV integrated clinic of RSCM. Methods. A retrospective cohort study was conducted among post-partum HIV patients who were given ARV therapy for PMTCT at HIV intergrated clinic of Cipto Mangunkusumo Hospital from January 2004 to May 2014. Evaluation of one year retention in care after PMTCT was performed by observing medical records of the patient. The collected data were factors associated with one year after delivery retention …

Clinical Characteristic And Prevalence Of Invasive Candidiasis Patient In Cipto Mangunkusumo Hospital, Kemal Fariz Kalista, Lie Khie Chen, Retno Wahyuningsih, Cleopas Martin Rumende

Jurnal Penyakit Dalam Indonesia

Introduction. Incidence of invasive fungal infections (IFI) are reportedly increasing in many countries. Candida is the most common cause of IFI. This study was conducted to determine the prevalence, clinical characteristics, and etiologic pathogen in adult patients with invasive candidiasis (IC) at Cipto Mangunkusumo Hhospital. Methods. This was a cross sectional study with restropective data collection fromof septic patients that’ medical records hospitalized in January 2012 until June 2014. Subjects were selected based on EORTC/MSG 2008 diagnostic criteria for IC. Demographic data, clinical and supporting data, diagnosis, etiologic pathogens, antibiotics, antifungal, outcome, and length of stay were recorded. Results. The …

Correlation Between Disease Duration, Disease Activity Scoreand Disability Score With Diastolic Dysfunction In Rheumatoidarthritis Women In Dr. Cipto Mangunkusumo Hospital, Dono Antono, Bernard Agus Sakti Dhaki, Harry Isbagio, Hamzah Shatri

Jurnal Penyakit Dalam Indonesia

Introduction. There are only few studies about correlation between non traditional risk factor and diastolic dysfunction in RA patients. This study aims to determinate the correlation between non traditional risk factors, including disease duration, disease activity and disability score with the diastolic dysfunction of women with RA. Methods. A cross-sectional, consecutive sampling study was conducted to 52 RA women without any previous cardiovascular disease history. All participants underwent an echocardiography to assess diastolic dysfunction and other findings associated. Duration of disease was assesed by direct interview, while the disease activity by calculating DAS28 and disability score by HAQ-DI. Results. Diastolic …

Risiko Kardiovaskuler Pada Pasien Artritis Reumatoid, Rudy Hidayat

Jurnal Penyakit Dalam Indonesia

No abstract provided.

A 30 Years Old Woman With Sepsis, Skin And Soft Tissueinfection, And Obesity, Franzeska Adm Widinartasari, Muhammad Ali Sodiq, Muchlis Au Sofro

Jurnal Penyakit Dalam Indonesia

Obesity increases morbidity and mortality through its multiple efects on nearly every human system. Obesity has efect on the immune response which leads to susceptibility to infections. ß lactamases are bacterial enzymes that inactivate ß-lactam antibiotics by hydrolysis. One group of ß lactamases, extended-spectrum ß lactamases (ESBLs), have the ability to hydrolyse and cause resistance to various types of the newer ß-lactam antibiotics. The management of skin and soft tissue infection with polymicrobial infection and multi drug resistance can be challenging problem. We present a case of an obese patient with polymicrobial SSTI. bPatient showed clinical sign of sepsis with …