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Medical School Watercooler Newsletter - October 1, 2017, Lindsey Lyle

Watercooler Newsletter

This is the October 1, 2017 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA Welcomes Dr. Anna Foust

Mark Your Calendar: Randall W. Powell Endowed Memorial Lectureship

Basic Medical Sciences Graduate Program Student Receives Edwin R. Hughes Award

October Med School Café - ‘I’m Short of Breath - Let’s Talk About Asthma'

USA College of Medicine Business Office Shows School Spirit with Jagfeast

Opportunities And Challenges For Self-Monitoring Technologies For Healthy Aging: An In-Situ Study, Mirana Randriambelonoro, Yu Chen, Onur Yuruten, Pearl Pu

Faculty Publications, Information Systems & Technology

The current need to adopt a healthy lifestyle opens the way for researchers to investigate the efficiency of using technology to motivate a change towards such behavior. Senior people’s technology adoption barriers have been largely investigated in previous research but remain unclear to design efficient solution to promote behavior change in the long term. In this paper, we present the findings of an experiment with 20 older adults using pervasive sensors for 6 weeks at their homes. In particular, we present their attitudes for physical activities and self-monitoring technologies before and after the actual usage. We then discuss the opportunities …

Perceived Stress Levels May Impact Upper Extremity Function Among Women Treated For Breast Cancer, Mary Insana Fisher, Anne Fleischer, Lynn Hendricks, Megan Mcclure, Kim Parent, Renee Roberts

Physical Therapy Faculty Publications

Purpose/Hypothesis: Women treated for breast cancer report ongoing upper extremity disability with functional limitations; however, objective measures do not appear to explain the extent of perceived dysfunction. The purpose of this study was to investigate the relationship between perceived stress level, fear of physical activity, self-reported upper extremity function, and objective measures of upper extremity function including range of motion (ROM), strength, and muscular endurance, among women treated for breast cancer.

Number of Subjects: 25

Materials/Methods: Women diagnosed with stage I-III breast cancer in the past 12-60 months were evaluated using the Disabilities of the Arm, Shoulder and Hand (DASH), …

Re:Align, George Washington University Cancer Center

RE:

No abstract provided.

Gw Nursing, Fall 2017, George Washington University, School Of Nursing

GW Nursing Magazine

No abstract provided.

Acculturation, Stress And Birth Outcomes In Mexican And Mexican American Women, Paulette A. Chaponniere

Peer Reviewed Articles

Purpose: This study examined the relationships between stress, stress buffers, acculturation and birth outcomes of infants born to 81 Mexican and Mexican American women living in West Michigan.

Method: An interrupted times series design was used to collect data prior to labor and delivery. Neuman’s Systems Model was used as the theoretical framework as it illustrates how stress impacts health outcomes. Women were recruited from local health and community agencies. Interviews were conducted in English or Spanish as desired by the subject using standardized questionnaires.

Results: Acculturation was negatively correlated with age (r = -.378, p < 0.001) and social support (r = -.258, p = .02). Bicultural women had the highest mean birth weight, and very Mexican–oriented women had the longest gestation. The third trimester of pregnancy was significantly different from the second trimester for stress, coping and social support. The women least integrated in either culture, e.g. marginalized (ARSMA-II), had the most stress. Spiritual coping predicted weight (β = .278) while pregnancy distress (β = -.237) and sense of belonging (β = -.258) predicted length of gestation.

Conclusion: Pregnancy-related distress was …

Gross Motor Outcomes After Dynamic Weight-Bearing In 2 Children With Trunk Hypotonia: A Case Series, Elizabeth Ardolino, Megan Flores, Kathleen Manella

Physical Therapy Collection

NTRODUCTION:

Children with trunk hypotonia may have limited ability to maintain an upright weight-bearing position, resulting in decreased postural control and a delay in achieving gross motor milestones.

PURPOSE:

The purpose of this case series is to report the effect of a home-based dynamic standing program on postural control and gross motor activity in 2 children with trunk hypotonia.

DESCRIPTIONS:

Child 1 (aged 24 months, Gross Motor Function Classification Scale Level IV) and Child 2 (aged 21 months, Gross Motor Function Classification Scale Level V) participated in a standing program using the Upsee harness at home 3 days per week …

The Effects Of Spinal Mobilizations, Manual Stretching, And Exercises In The Treatment Of Testicular Pain: A Case Report, Kunal Bhanot, Navpreet Kaur, R Chambers

Physical Therapy Collection

The purpose of this case report was to describe the PT management in relieving testicular pain related to genitofemoral nerve entrapment.

Estrogens As Neuroprotectants: Estrogenic Actions In The Context Of Cognitive Aging And Brain Injury, E. B. Engler-Chiurazzi, C. M. Brown, J. M. Povroznik, J. W. Simpkins

Clinical and Translational Science Institute

There is ample empirical evidence to support the notion that the biological impacts of estrogen extend beyond the gonads to other bodily systems, including the brain and behavior. Converging preclinical findings have indicated a neuroprotective role for estrogen in a variety of experimental models of cognitive function and brain insult. However, the surprising null or even detrimental findings of several large clinical trials evaluating the ability of estrogen-containing hormone treatments to protect against age-related brain changes and insults, including cognitive aging and brain injury, led to hesitation by both clinicians and patients in the use of exogenous estrogenic treatments for …

Clinical Outcome Of Carotid Artery Stenting According To Provider Specialty And Volume, Ali F. Aburahma, John E. Campbell, Nizar Hariri, Joseph Aburahma, L. Scott Dean, Mark C. Bates, Aravinda Nanjundappa, Patrick A. Stone, Ace O'Vil

Clinical and Translational Science Institute

Background—Several studies have demonstrated better outcomes for carotid endarterectomy with high-volume hospitals and providers. However, only a few studies have reported on the impact of operator specialty/volume on the perioperative outcome of carotid artery stenting (CAS). This study will analyze the correlation of CAS outcomes and provider specialty and volume. Methods—Prospectively collected data of CAS procedures done at our institution during a 10- year period were analyzed. Major adverse events (MAEs; 30-day stroke, myocardial infarction, and death) were compared according to provider specialty (vascular surgeons [VSs], interventional cardiologists [ICs], interventional radiologists [IRs], interventional vascular medicine [IVM]), and volume (≥5 CAS/year …

An Electronic Health Record Data-Driven Model For Identifying Older Adults At Risk Of Unintentional Falls, Adam Baus, Jeffrey Coben, Keith Zullig, Cecil Pollard, Charles Mullett, Henry Taylor, Jill Cochran, Traci Jarrett, Dustin Long

Clinical and Translational Science Institute

Screening for risk of unintentional falls remains low in the primary care setting because of the time constraints of brief office visits. National studies suggest that physicians caring for older adults provide recommended fall risk screening only 30 to 37 percent of the time. Given prior success in developing methods for repurposing electronic health record data for the identification of fall risk, this study involves building a model in which electronic health record data could be applied for use in clinical decision support to bolster screening by proactively identifying patients for whom screening would be beneficial and targeting efforts specifically …

Auditory Object Perception: A Neurobiological Model And Prospective Review, Julie A. Brefczynski-Lewis, James W. Lewis

Clinical and Translational Science Institute

Interaction with the world is a multisensory experience, but most of what is known about the neural correlates of perception comes from studying vision. Auditory inputs enter cortex with its own set of unique qualities, and leads to use in oral communication, speech, music, and the understanding of emotional and intentional states of others, all of which are central to the human experience. To better understand how the auditory system develops, recovers after injury, and how it may have transitioned in its functions over the course of hominin evolution, advances are needed in models of how the human brain is …

Relationship Between Adherence To Individual Goals Within The 5-2-1-0 Guidelines For Obesity Prevention And Number Of Pacer Laps In Adolescents, Kibum Cho, Emily Jones, Christa Lilly, Sean Bulger, Luciana Braga, Eloise Elliott

Clinical and Translational Science Institute

BACKGROUND—The purpose of this study was to evaluate the relationship between adolescents’ adherence to the 5-2-1-0 goals and the number of completed Progressive Cardiovascular Endurance Run (PACER) laps. METHODS—Participants included 1792 students aged 10 to 16 years who were randomly selected across 9 data collection periods between 2012 and 2014. The Survey of Physical Activity and Nutrition was used to measure time spent in physical activity and sedentary behavior, and dietary intake and the dependent variable was the number of PACER laps achieved. The KruskalWallis test and pairwise post hoc comparisons were conducted. RESULTS—Only 0.95% (N = 17) participants met …

Prognostic Significance Of Corticotroph Staining In Radiosurgery For Non- Functioning Pituitary Adenomas: A Multicenter Study, Or Cohen-Inbar, Zhiyuan Xu, Cheng Chia Lee, Chin Chun Wu, Tomáš Chytka, Danilo Silva, Mayur Sharma, Hesham Radwan, Inga S. Grills, Brandon Nguyen, Zaid Siddiqui, David Mathieu, Christian Iorio Morin, Amparo Wolf, Christopher P. Cifarelli, Daniel T. Cifarelli, L. Dade Lunsford, Douglas Kondziolka, Jason P. Sheehan

Clinical and Translational Science Institute

Silent corticotroph staining pituitary adenoma (SCA) represents an uncommon subset of Non-Functioning adenomas (NFAs), hypothesized to be more locally aggressive. In this retrospective multicenter study, we investigate the safety and effectiveness of Stereotactic Radiosurgery (SRS) in patients with SCA compared with other non-SCA NFA’s. Eight centers participating in the International Gamma-Knife Research Foundation (IGKRF) contributed to this study. Outcomes of 50 patients with confirmed SCAs and 307 patients with confirmed non-SCA NFA’s treated with SRS were evaluated. Groups were matched. SCA was characterized by a lack of clinical evidence of Cushing disease, yet with positive immunostaining for corticotroph. Median age …

Trends In Brain Cancer Mortality Among U.S. Gulf War Veterans: 21 Year Follow-Up., Shannon K. Barth, Erin K. Dursa, Robert M. Bossarte, Aaron I. Schneiderman

Clinical and Translational Science Institute

Objective—Previous mortality studies of U.S. Gulf War veterans through 2000 and 2004 have shown an increased risk of brain cancer mortality among some deployed individuals. When veterans possibly exposed to environmental contaminants associated with demolition of the Khamisiyah Ammunition Storage Facility at Khamisiyah, Iraq, have been compared to contemporaneously deployed unexposed veterans, the results have suggested increased risk for mortality from brain cancer among the exposed. Brain cancer mortality risk in this cohort has not been updated since 2004. Methods—This study analyzes the risk for brain cancer mortality between 1991–2011 through two series of comparisons: U.S. Gulf War deployed and …

Trip Database: Turning Research Into Practice For Evidence-Based Care, Gregg A. Stevens, Lori Fitterling, F. Victoria Kelly

Library Faculty Publications

Trip Database is a freely available search engine based in the United Kingdom. Trip directs users to journal articles, practice guidelines, and other research to support evidence-based medical practice. This column includes sample searches in both the free version and in the subscription Pro version.

Dental Practice Success Vol. 4 No. 3, American Dental Association, Publishing Division

Dental Practice Success

No abstract provided.

Direct Antioxidant Properties Of Methotrexate: Inhibition Of Malondialdehyde-Acetaldehyde-Protein Adduct Formation And Superoxide Scavenging., Matthew C. Zimmerman, Dahn L. Clemens, Michael J. Duryee, Cleofes Sarmiento, Andrew Chiou, Carlos D. Hunter, Jun Tian, Lynell W. Klassen, James R. O'Dell, Geoffrey M. Thiele, Ted R. Mikuls, Daniel R. Anderson

Journal Articles: Cellular & Integrative Physiology

Methotrexate (MTX) is an immunosuppressant commonly used for the treatment of autoimmune diseases. Recent observations have shown that patients treated with MTX also exhibit a reduced risk for the development of cardiovascular disease (CVD). Although MTX reduces systemic inflammation and tissue damage, the mechanisms by which MTX exerts these beneficial effects are not entirely known. We have previously demonstrated that protein adducts formed by the interaction of malondialdehyde (MDA) and acetaldehyde (AA), known as MAA-protein adducts, are present in diseased tissues of individuals with rheumatoid arthritis (RA) or CVD. In previously reported studies, MAA-adducts were shown to be highly immunogenic, …

Community Paramedicine Pilot Programs: Lessons From Maine, Karen B. Pearson Mlis, Ma, George Shaler Mph

Emergency Medical Services (EMS)

Community paramedicine programs are beginning to flourish across the nation, and the need to provide demonstration or pilot programs is essential to providing a consistent and high-level standard for this model of care. While the overarching goals are to align with the Triple Aim, piloting a community paramedicine program also allows each community to develop and implement a program tailored to the healthcare needs of their specific community. A successful program builds the evidence base that can then be used to create legislative change necessary to financially sustain this model of care across the healthcare delivery system. This article provides …

Increasing Fitness Engagement Among Ohiohealth Employees, Kristen Goins

Masters Theses/Capstone Projects

This presentation focuses on how to increase fitness engagement among the employees of a large medical facility.

Philosophy Bakes No Bread, Babette Babich

Articles and Chapters in Academic Book Collections

Philosophy Bakes No Bread

Far from baking bread, far from practical applicability, philosophy traditionally sought to explain the world, ideally so. Thus, when Marx argued that it was high time philosophy “change the world,” his was a revolutionary challenge. Today, philosophy is an analytic affair and analytic philosophers seek less to explain the world than to squirrel out arguments or, more descriptively, to resolve the minutiae of this or that name problem. Faced with diminishing student demand, analytic philosophers have taken to urging that everyone from primary school students to scientists be required to study (analytic) philosophy. Just so, applied …

One Hospital's Path To Develop An Ivc Filter Registry, Emily Keltner Bs, Ma, T. Eric White Md, Lisa Hollister, Denise Milestone Rn

Parkview Heart Institute

Background- Inferior Vena Cava (IVC) filters are small cage like devices placed percutaneously into the inferior vena cava to prevent propagation of thrombus into the pulmonary arteries. Currently there are two available types of filters, permanent filters and retrievable filters. In 2014, the FDA initiated a comprehensive analysis of filter placement and issued a statement recommending implanting physicians and clinicians responsible for the ongoing care of patients with retrievable IVC filters consider removing the filter as soon as protection from pulmonary embolism is no longer needed. Prior to the hospital’s structured system, there was a low rate of follow-up. The …

Department Of Surgery Update, October 2017, Wright State University Department Of Surgery

Department of Surgery Updates

A three page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, and more.

Insight - October 2017, Dugoni School Of Dentistry

Insight

Insight is a quarterly newsletter celebrating some of the many accomplishments from the community of researchers at University of the Pacific, Arthur A. Dugoni School of Dentistry. (Note, some links require a login/password)

Pololeo Y Protección: Las Barreras De Acceso A Métodos Anticonceptivos Para Adolescentes Vulnerables En La Comuna De Macul, Santiago De Chile / Pololeo Y Protección: Barriers To Access Contraceptive Methods For Vulnerable Adolescents In The District Of Macul, Santiago De Chile, Louisa Boswell

Independent Study Project (ISP) Collection

El embarazo adolescente sigue siendo un problema de salud pública al nivel nacional en Chile. Aunque por ley, todos tienen el derecho a una educación sexual y a elegir un método de control de fecundidad, todavía existen casos de embarazos no planificados, particularmente entre adolescentes. Este estudio investigó las barreras que limitan el acceso a métodos anticonceptivos para adolescentes, enfocando primariamente en el sistema público en la Región Metropolitana. Específicamente, la investigación consideró las adolescentes de la comuna de Macul, utilizando muestras de un colegio local y dos centros de salud familiar para hacer conclusiones. La investigadora entrevistó a matronas …

Women Of Leh Town, Ladakh: An Overview Of Perceptions Of Health, Health-Seeking Behaviors, And Access To Health Care, Sophia Marion

Independent Study Project (ISP) Collection

The following study seeks to investigate access to health care services and perceptions of health care among women residing in traditional farming communities around the Ladakh region, and to analyze perspectives on health, health-seeking behavior, and access to health care. This project was prompted by the fact that health care in this region is understudied. This study also focuses on marginalized communities including local women and immigrant women. Methods used for the collection of data were qualitative interviews conducted with 24 women, as well as an amchi worker, doctors, and informal and formal conversations with people from different nongovernmental Organizations …

When Knowledge Flows: A Case Study Of Village Health Workers’ Motivations In Jamkhed, Selaem Hadera

Independent Study Project (ISP) Collection

Across the field of global health, there have been many attempts to cater to the health needs of the most marginalized populations. Community health workers (CHWs) are individuals that live in the communities they serve and are typically low-­‐income women with little to no formal education. After a period of training by their program, they enter their communities equipped as a bridge between the community and the health system. Although CHWs do play a substantial role in health delivery and education, the structure of CHW programs varies widely, but a common characteristic of these programs is that the CHWs are …

Combination Targeted Pulmonary Hypertension Therapy In The Resolution Of Dasatinib-Associated Pulmonary Arterial Hypertension., Arun Jose, Hind Rafei, Jalil Ahari

Medicine Faculty Publications

Dasatinib is a small-molecule tyrosine kinase inhibitor used in the treatment of hematological malignancies. Pulmonary arterial hypertension (PAH) is a rare but known complication. The mainstay of treatment is cessation of Dasatinib, and while clinical improvement is rapid, complete hemodynamic resolution of pulmonary hypertension (PH) still remains exceedingly uncommon. We present a case of Dasatinib-induced PAH in a woman with chronic myeloid leukemia, who demonstrated rapid and complete clinical and hemodynamic resolution following treatment with combination pulmonary vasodilator therapy using an endothelin receptor antagonist and a phosphodiesterase-5 inhibitor. This case suggests there may be an association between the use of …

Counseling Preferences Of Young Adults With Cancer., Jessica Taylor, Susan Kashubeck-West

Education Sciences and Professional Programs Faculty Works

This study examined preferences for counseling topics to discuss in individual, group, and family counseling among young adults with cancer, as well as their ranked preferences for attending individual, group, and family counseling. A sample of 320 young adults with cancer (18–39 years old) completed an online survey containing items relevant to young adults’ psychosocial needs. Participants rated anxiety, finances, sad feelings, sexual and intimacy concerns, and stress management as most helpful for individual counseling; finding social support and getting information about one’s medical situation as most helpful for group counseling; and no topics as most helpful for family counseling. …

Unrecognized Epidemic Kills Farmers, M. Susan Jones, Deborah B. Reed, Matthew L. Hunt

Nursing Faculty Publications

No abstract provided.