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Articles 11281 - 11310 of 14524
Full-Text Articles in Medicine and Health Sciences
The Knowledge And High Seroprevalence Of Hepatitis A In A High-Risk Group(Agricultural Reproductive-Aged Women) In The Southeastern Region Of Turkey, Nebi̇ye Yentür Doni̇, Zeynep Şi̇mşek, Gülcan Gürses, Fadi̇le Yildiz Zeyrek, Muhsi̇n Akbaba
The Knowledge And High Seroprevalence Of Hepatitis A In A High-Risk Group(Agricultural Reproductive-Aged Women) In The Southeastern Region Of Turkey, Nebi̇ye Yentür Doni̇, Zeynep Şi̇mşek, Gülcan Gürses, Fadi̇le Yildiz Zeyrek, Muhsi̇n Akbaba
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the seroprevalence of antihepatitis A virus (HAV), risk factors, and the knowledge of female farm workers living in the Southeastern Anatolia Region (SAR) of Turkey. Materials and methods: This representative cross-sectional survey was conducted between January and April of 2013 in the SAR. A total of 705 reproductive-aged women were randomly selected by clustering method using Epi Info software. The sera were analyzed for anti-HAV antibodies using ELISA. Sociodemographic information and the knowledge of female farm workers regarding hepatitis A were collected using a questionnaire. Results: Of the female farm workers, …
Relationship Of Peripheral Blood Neutrophil To Lymphocyteratio And Irritable Bowel Syndrome, Mustafa Güçlü, Ahmet Faruk Ağan
Relationship Of Peripheral Blood Neutrophil To Lymphocyteratio And Irritable Bowel Syndrome, Mustafa Güçlü, Ahmet Faruk Ağan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to determine the relationship between the peripheral blood neutrophil to lymphocyte ratio (NLR) and irritable bowel syndrome (IBS). Materials and methods: A total of 107 patients suffering from constipation-predominant IBS, diagnosed in accordance with the ROMA III criteria and having complete blood count tests, were enrolled in this study. All patients underwent total colonoscopy in order to rule out any probable underlying organic colonic pathology. Results: The control group consisted of 106 healthy people with no medical complaints. The peripheral blood NLR was 2.80 ± 2.52 on average in the IBS group. The NLR average was …
Neuroendocrine Disorder In Chronic Fatigue Syndrome, Slavica Tomic, Snezana Brkic, Dajana Lendak, Daniela Maric, Milica Medic-Stojanoska, Aleksandra Novakov-Mikic
Neuroendocrine Disorder In Chronic Fatigue Syndrome, Slavica Tomic, Snezana Brkic, Dajana Lendak, Daniela Maric, Milica Medic-Stojanoska, Aleksandra Novakov-Mikic
Turkish Journal of Medical Sciences
Background/aim: Neuroendocrine disorders are considered a possible pathogenetic mechanism in chronic fatigue syndrome (CFS). The aim of our study was to determine the function of the hypothalamic-pituitary-adrenal axis (HPA) and thyroid function in women of reproductive age suffering from CFS. Materials and methods: The study included 40 women suffering from CFS and 40 healthy women (15-45 years old). Serum levels of cortisol (0800 and 1800 hours), ACTH, total T4, total T3, and TSH were measured in all subjects. The Fibro Fatigue Scale was used for determination of fatigue level. Results: Cortisol serum levels were normal in both groups. The distinctively …
Relation Between Foot Pain And Plantar Pressure In Pregnancy, Tuncay Varol, Asli Göker, Eni̇s Cezayi̇rli̇, Serkan Özgür, Ayşe Tuç Yücel
Relation Between Foot Pain And Plantar Pressure In Pregnancy, Tuncay Varol, Asli Göker, Eni̇s Cezayi̇rli̇, Serkan Özgür, Ayşe Tuç Yücel
Turkish Journal of Medical Sciences
Background/aim: Hormonal and structural changes that occur during pregnancy cause alterations in body biomechanics. These alterations reach their peak in the last trimester. Adaptive changes that appear in the foot result in pain in the foot and ankle. Pedobarography is a noninvasive measurement method that can be used to understand the origin of such pain. Materials and methods: One hundred and thirty-one pregnant women who did not have a foot or ankle problem prior to pregnancy volunteered to take part in the study. Pain was quantified by a visual analog scale (VAS). A cut-off value of 2.95 was taken to …
Risk Factors For Recurrent Central Line-Associated Bloodstream Infections In Apediatric Intensive Care Unit, Rana İşgüder, İlker Devri̇m, Gökhan Ceylan, Ahu Kara, Gamze Gülfi̇dan, Hasan Ağin
Risk Factors For Recurrent Central Line-Associated Bloodstream Infections In Apediatric Intensive Care Unit, Rana İşgüder, İlker Devri̇m, Gökhan Ceylan, Ahu Kara, Gamze Gülfi̇dan, Hasan Ağin
Turkish Journal of Medical Sciences
Background/aim: It is recommended that a central venous catheter (CVC) be removed if central line-associated bloodstream infection (CLABSI) has been diagnosed. The objective of this retrospective study was to evaluate the risk factors for recurrent CLABSI in reinserted catheters in a pediatric intensive care unit. Materials and methods: Patients with recurrent and nonrecurrent CLABSI were compared in terms of the catheter exchange interval, the interval between negative blood culture and reinsertion of the CVC, and the pre-/reinsertion treatment duration. Results: Thirty-one patients with initial CLABSI had reinserted CVCs, and 12 (38.7%) of these patients were diagnosed with recurrent CLABSI. In …
Endovascular Embolization In The Management Of Traumatic Andpostoperative Abdominopelvic Bleeding: A Single-Center Experience, Di̇lek Sağlam, Hasan Di̇nç, Abdulkadi̇r Gündüz, Ayşegül Cansu, Mehmet Hali̇l Öztürk
Endovascular Embolization In The Management Of Traumatic Andpostoperative Abdominopelvic Bleeding: A Single-Center Experience, Di̇lek Sağlam, Hasan Di̇nç, Abdulkadi̇r Gündüz, Ayşegül Cansu, Mehmet Hali̇l Öztürk
Turkish Journal of Medical Sciences
Background/aim: Endovascular embolization is widely used instead of surgery in the treatment of traumatic and postoperative abdominopelvic bleeding. The objective of this study is to evaluate the efficiency of computed tomography in the determination of active bleeding and the efficiency of endovascular embolization in traumatic and postoperative abdominopelvic bleeding. Materials and methods: Thirty-one patients admitted to our hospital with traumatic and postoperative abdominopelvic bleeding between January 2006 and September 2012 and treated with endovascular embolization were retrospectively enrolled in the study. In 15 hemodynamically stable patients, abdominal computed tomography was performed to detect the presence and/or localization of the hemorrhage. …
A Study Of The Chikungunya Virus In Humans In Turkey, Tuğba Atalay, Sedat Kaygusuz, Ahmet Kürşat Azkur
A Study Of The Chikungunya Virus In Humans In Turkey, Tuğba Atalay, Sedat Kaygusuz, Ahmet Kürşat Azkur
Turkish Journal of Medical Sciences
Background/aim: The chikungunya virus (CHIKV) is a mosquito-borne disease and has recently been causing explosive outbreaks. The CHIKV has spread throughout all continents. Although the first chikungunya case imported from India to Turkey was reported in 2012, there is no detailed epidemiologic study in Turkey yet. The aim of this study was to investigate the seroprevalence of the CHIKV in Turkey. Materials and methods: ELISA was used to screen 500 random serum samples of healthy people collected from Kırıkkale, which is located in central Anatolia in Turkey. The results were verified by indirect immunofluorescence test (IIFT). Results: The results showed …
Risk Factors For Colistin-Associated Nephrotoxicity And Mortality In Critically Ill Patients, Hüseyi̇n Özkarakaş, Işil Köse, Çi̇ler Zi̇nci̇rci̇oğlu, Si̇bel Ersan, Gürsel Ersan, Ni̇met Şenoğlu, Şükran Köse, Riza Hakan Erbay
Risk Factors For Colistin-Associated Nephrotoxicity And Mortality In Critically Ill Patients, Hüseyi̇n Özkarakaş, Işil Köse, Çi̇ler Zi̇nci̇rci̇oğlu, Si̇bel Ersan, Gürsel Ersan, Ni̇met Şenoğlu, Şükran Köse, Riza Hakan Erbay
Turkish Journal of Medical Sciences
Background/aim: Colistin is gaining popularity against multidrug-resistant bacteria. The primary concern with colistin is its nephrotoxicity (NT). The aim of this study was to evaluate the incidence and risk factors for NT and to evaluate the risk factors for mortality in the toxicity group. Materials and methods: NT was defined according to the RIFLE criteria. Data of patients who did or did not develop NT were compared. Positive and negative predictive values, risk ratio, and correlation coefficients were calculated. Results: NT was seen in 39 patients (70%). Hypoalbuminemia, old age, and the use of vasopressors (VPs) were associated with NT. …
The Prevalence Of Abdominal Obesity Is Remarkable For Underweightand Normal Weight Adolescent Girls, Ni̇lüfer Tek, Nevi̇n Şanlier, Duygu Türközü
The Prevalence Of Abdominal Obesity Is Remarkable For Underweightand Normal Weight Adolescent Girls, Ni̇lüfer Tek, Nevi̇n Şanlier, Duygu Türközü
Turkish Journal of Medical Sciences
Background/aim: Obesity is a global public health challenge. This study was carried out in order to determine the prevalence of obesity and abdominal obesity in Turkish adolescent girls. Materials and methods: A cross-sectional study was conducted in a total of 1111 adolescent girls aged 12?18 years. The subjects were classified into four groups: underweight, normal, overweight, and obese. Abdominal obesity was defined according to waist circumference (WC) $\geq$ 90th percentile for Turkish adolescent population references (12-17 years) and waist-to-height ratio (WHtR) $\geq$ 0.5. Results: The prevalence of underweight was 17.4%, normal weight 68.5%, overweight 12.1%, and obese 2.0%. A total …
Sleep Quality, Sleeping Postures, And Sleeping Equipmentin Patients With Ankylosing Spondylitis, Servet Yolbaş, Ahmet Yildirim, Deccane Düzenci̇, Bariş Gündoğdu, Meti̇n Özgen, Süleyman Serdar Koca
Sleep Quality, Sleeping Postures, And Sleeping Equipmentin Patients With Ankylosing Spondylitis, Servet Yolbaş, Ahmet Yildirim, Deccane Düzenci̇, Bariş Gündoğdu, Meti̇n Özgen, Süleyman Serdar Koca
Turkish Journal of Medical Sciences
Background/aim: Inflammatory back pain, spinal stiffness, and limited spinal mobility are characteristic features of ankylosing spondylitis (AS). Sleeping postures can affect and/or reflect sleeping disturbances. The aim of the study was to evaluate sleeping postures and sleep disturbances in patients with AS. Materials and methods: Seventy-seven patients with AS and 49 healthy controls were enrolled. The Pittsburgh Sleep Quality Index (PSQI) and the Insomnia Severity Index (ISI) were applied to both groups. The most common sleeping postures were noted. Results: There was no significant difference between the groups in terms of sleeping postures. Total PSQI and ISI scores were higher …
Evaluation Of Lipid Profiles In Patients Treated With Capecitabine, Nursel Sürmeli̇oğlu, Semra Paydaş, Yusuf Karataş, Gülşah Seydaoğlu
Evaluation Of Lipid Profiles In Patients Treated With Capecitabine, Nursel Sürmeli̇oğlu, Semra Paydaş, Yusuf Karataş, Gülşah Seydaoğlu
Turkish Journal of Medical Sciences
Background/aim: Capecitabine is a prodrug of 5-fluorouracil and has shown significant antitumor activity. The main adverse effects are hand-foot syndrome, diarrhea, and dermatitis. In recent years, hypertriglyceridemia has been reported in patients treated with capecitabine. Dyslipidemia is a rare but important side effect of capecitabine. The aim of this study is to examine the changes in lipid levels during capecitabine treatment and to raise awareness of pharmacovigilance. Materials and methods: In this retrospective study, it was aimed to analyze lipid metabolism after capecitabine treatment and is intended to contribute to the formation of a pharmacoepidemiological database. For this purpose, triglyceride, …
Tlr2 (-196 To -174 Ins/Del) And Tlr3 (1377c>T) As Biomarkers For Nasopharyngeal Cancer In Tunisia, Lamia Makni, Amira Messadi, Sabrina Zidi, Ezzedine Gazouani, Amel Mezlini, Besma Yacoubi-Loueslati
Tlr2 (-196 To -174 Ins/Del) And Tlr3 (1377c>T) As Biomarkers For Nasopharyngeal Cancer In Tunisia, Lamia Makni, Amira Messadi, Sabrina Zidi, Ezzedine Gazouani, Amel Mezlini, Besma Yacoubi-Loueslati
Turkish Journal of Medical Sciences
Background/aim: We evaluated the association of TLR2 (-196 to -174 Ins/Del) and TLR3 (1377 C>T) as potential risk factors for nasopharyngeal carcinoma (NPC) in Tunisians. Material and methods: The study subjects comprised 137 NPC patients and 164 cancer-free control subjects. TLR2 genotyping was done by PCR and TLR3 genotyping was performed by PCR-RFLP. Results: Minor allele frequency (MAF) and genotypes of TLR3 (1377 C>T) were comparable between NPC patients and controls. Significantly higher MAF and TLR2-containing Del allele genotypes of TLR2 (-196 to -174 Ins/Del) were seen in NPC patients compared to controls [OR (95% CI) = 2.10 …
Cross-Cultural Adaptation And Psychometric Assessment Of The Turkishversion Of The Vulnerability To Abuse Screening Scale, Güler Duru Aşi̇ret, Gülcan Bağçi̇van, Münevver Özcan, Beste Başak Eröksüz, Nalan Akbayrak, Nuran Akdemi̇r
Cross-Cultural Adaptation And Psychometric Assessment Of The Turkishversion Of The Vulnerability To Abuse Screening Scale, Güler Duru Aşi̇ret, Gülcan Bağçi̇van, Münevver Özcan, Beste Başak Eröksüz, Nalan Akbayrak, Nuran Akdemi̇r
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate the reliability and validity of the Turkish version of the Vulnerability to Abuse Screening Scale (VASS). Materials and methods: This was a methodological study. The sample included 140 elderly individuals. Data were collected by using a questionnaire form, the VASS, and the Geriatric Depression Scale (GDS). The Cronbach alpha value was calculated and test?retest reliability was tested for the reliability analyses. Results: The Cronbach alpha value calculated for the VASS (12 items) was 0.819. There was no difference between test and retest mean scores of the VASS. A statistically significantly positive …
A Nationwide Evaluation Of Off-Label Drug Utilization In Turkey, Emi̇ne Nur Özdamar, Ahmet Akici, Ali̇ Alkan, Banu Bayar, Hakki Gürsöz
A Nationwide Evaluation Of Off-Label Drug Utilization In Turkey, Emi̇ne Nur Özdamar, Ahmet Akici, Ali̇ Alkan, Banu Bayar, Hakki Gürsöz
Turkish Journal of Medical Sciences
Background/aim: Off-label drug use (OLDU) is under the control of the Turkish Medicines and Medical Devices Agency (TMMDA) in Turkey. It was aimed to investigate demographic and medical features of patients with OLDU applications in Turkey. Materials and methods: A total of 4426 electronic OLDU application records of the TMMDA were evaluated retrospectively. Information regarding patients? demographic characteristics, diagnoses, requested drugs, institutions, and specialties of the physicians were evaluated. Results: OLDU applications were mostly made by rheumatologists (21.5%) and 95.2% of them were approved by the TMMDA. The mean age of the patients was 35 years and 54.4% of them …
A Fully Liquid Dtap-Ipv-Hb-Prp-T Hexavalent Vaccine For Primaryand Booster Vaccination Of Healthy Turkish Infants And Toddlers, Mehmet Ceyhan, İnci̇ Yildirim, Hasan Tezer, İlker Devri̇m, Emmanuel Feroldi
A Fully Liquid Dtap-Ipv-Hb-Prp-T Hexavalent Vaccine For Primaryand Booster Vaccination Of Healthy Turkish Infants And Toddlers, Mehmet Ceyhan, İnci̇ Yildirim, Hasan Tezer, İlker Devri̇m, Emmanuel Feroldi
Turkish Journal of Medical Sciences
Background/aim: Immunogenicity and safety of a primary series of a fully liquid, hexavalent DTaP-IPV-HB-PRP-T vaccine given at 2, 3, and 4 months of age compared to licensed comparators and a DTaP-IPV-HB-PRP-T booster at 15?18 months were evaluated. Materials and methods: This was a Phase III, randomized, open-label trial. Primary series (no hepatitis B [HB] at birth) of DTaP-IPV-HB-PRP-T (N = 155) (group 1) or licensed control vaccines (DTaP-IPV//PRP-T and standalone HB: N = 155) (group 2) and DTaP-IPV-HB-PRP-T booster were administered. Noninferiority was evaluated 1 month postprimary series for anti-HB seroprotection (SP). All other analyses were descriptive. Safety was assessed …
Plasma Human Leukocyte Antigen-G (Hla-G) In Patients With Thyroid Cancer, Murat Akin, Lati̇fe Arzu Aral, Aydin Yavuz, Harun Karabacak, Kürşat Di̇kmen, Hasan Bostanci
Plasma Human Leukocyte Antigen-G (Hla-G) In Patients With Thyroid Cancer, Murat Akin, Lati̇fe Arzu Aral, Aydin Yavuz, Harun Karabacak, Kürşat Di̇kmen, Hasan Bostanci
Turkish Journal of Medical Sciences
Background/aim: A number of tumor markers detected in the serum or pathological specimens using immunohistochemical methods are used for early detection of malignancies and postoperative follow-up. Human leukocyte antigen-G (HLA-G) is a nonclassic HLA class I molecule. Recent studies suggested a relationship between HLA-G positivity and the stage or the phenotype of the malignancy. In this study, the relationship between serum HLA-G positivity and thyroid cancer was investigated. Materials and methods: Fifty patients with thyroid cancer and 45 healthy volunteers were included in this study. Serum HLA-G levels were measured using ELISA. Results: HLA-G was positive in only 3 out …
Application Of Hemoperfusion In Severe Acute Organophosphorus Pesticide Poisoning, Zhenhe Li, Guixia Wang, Guodong Zhen, Yuliang Zhang, Jiaqiang Liu, Shanmei Liu
Application Of Hemoperfusion In Severe Acute Organophosphorus Pesticide Poisoning, Zhenhe Li, Guixia Wang, Guodong Zhen, Yuliang Zhang, Jiaqiang Liu, Shanmei Liu
Turkish Journal of Medical Sciences
Background/aim: The aim of this research is to investigate the clinical efficacy of hemoperfusion in the treatment of severe acute organophosphorus pesticide poisoning (AOPP). Materials and methods: Patients meeting the inclusion criteria were divided into Groups 1 and 2 according to whether hemoperfusion was applied or not. Group 2 was observed as the control group. Conventional therapy for AOPP was given to Groups 1 and 2. Besides conventional treatment, patients in Group 1 were also treated with hemoperfusion therapy. Cholinesterase activity and blood glucose concentration were tested before hemoperfusion and for the first 3 days afterwards. The recovery time of …
Pediatric Pityriasis Rosea, Giulia Ciccarese, Aurora Parodi, Francesco Drago
Pediatric Pityriasis Rosea, Giulia Ciccarese, Aurora Parodi, Francesco Drago
Turkish Journal of Medical Sciences
No abstract provided.
Impact Of Body Mass Index, Waist Circumference And Pfannenstiel Sitetissue Thickness, And Elastosonography On Operative Parameters, Serap Gülteki̇n, İsmai̇l Burak Gülteki̇n, Zehra Vural Yilmaz, Bi̇lal İçer, Afra Alkan, Tuncay Küçüközkan
Impact Of Body Mass Index, Waist Circumference And Pfannenstiel Sitetissue Thickness, And Elastosonography On Operative Parameters, Serap Gülteki̇n, İsmai̇l Burak Gülteki̇n, Zehra Vural Yilmaz, Bi̇lal İçer, Afra Alkan, Tuncay Küçüközkan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the impact of body fat distribution measured by body mass index (BMI), waist circumference (WC) and Pfannenstiel incision site tissue thickness, and elastosonography on bleeding and operation time during cesarean delivery.Materials and methods: A prospective study was made of 52 healthy, term pregnant women with prior cesarean deliveries. The impact of BMI, WC, incision site thickness, and elastosonography on preoperative and postoperative differences in hemoglobin (Hb) and hematocrit (Htc) levels and operation times was evaluated.Results: A moderate negative relationship was found between Htc levels and WC. Htc levels were found to decrease by 0.148 …
Eleven Patients With Primary Thyroid Lymphoma: A Single Center Experience, Hasan Bostanci, Kürşat Di̇kmen, Nalan Akyürek, Ahmet Çağri Büyükkasap, Aydin Yavuz, Mehmet Muhi̇tti̇n Yalçin, Murat Akin
Eleven Patients With Primary Thyroid Lymphoma: A Single Center Experience, Hasan Bostanci, Kürşat Di̇kmen, Nalan Akyürek, Ahmet Çağri Büyükkasap, Aydin Yavuz, Mehmet Muhi̇tti̇n Yalçin, Murat Akin
Turkish Journal of Medical Sciences
Background/aim: Primary thyroid lymphoma (PTL) is a very rare thyroid malignancy. It should be diagnosed and treated immediately and accurately. Our aim was to evaluate the diagnostic methods and treatment results for patients with PTL.Materials and methods: We retrospectively evaluated the records of 11 patients with PTL from 2009 to 2015, diagnosed at our institute. Age, sex, stage, histopathologic type, presence of Hashimoto's thyroiditis, diagnostic methods, treatment types, and recurrence were examined.Results: Six patients were female, 5 were male, and the median age of the patients was 61 years (range: 15-76 years). All patients had a large palpable mass in …
The Effect Of Antidiuretic Hormone On Urine And Serum Electrolyte Levelsin Children With Primary Monosymptomatic Nocturnal Enuresis, Nesri̇n Taş, Yaşar Kandur, Hati̇ce Ki̇bri̇ya Fi̇dan, Hüsnü Oğuz Söylemezoğlu
The Effect Of Antidiuretic Hormone On Urine And Serum Electrolyte Levelsin Children With Primary Monosymptomatic Nocturnal Enuresis, Nesri̇n Taş, Yaşar Kandur, Hati̇ce Ki̇bri̇ya Fi̇dan, Hüsnü Oğuz Söylemezoğlu
Turkish Journal of Medical Sciences
Background/aim: The data concerning the effects of desmopressin on water/electrolyte disturbances of children with primary monosymptomatic nocturnal enuresis (PMNE) are limited. In the present study we aimed to evaluate the effect and tolerability of desmopressin on blood and urine electrolytes and osmolality in PMNE.Materials and methods: Thirty-five children with PMNE between the ages of 5 and 15 participated in the study. Patients collected urine during the daytime and acknowledged the night time fluid restriction before starting to use the desmopressin tablets. The medication was taken orally at least 1 h before bedtime. Blood and urine samples were collected before the …
Assessment Of Repolarization Abnormalities In Baseline Electrocardiograms Of Patients With Myocarditis, Haci Murat Güneş, Gamze Babur Güler, Ekrem Güler, Gülteki̇n Günhan Demi̇r, Mehmet Kami̇l Teber, Fi̇li̇z Kizilirmak Yilmaz, Beytullah Çakal, Bi̇lal Boztosun
Assessment Of Repolarization Abnormalities In Baseline Electrocardiograms Of Patients With Myocarditis, Haci Murat Güneş, Gamze Babur Güler, Ekrem Güler, Gülteki̇n Günhan Demi̇r, Mehmet Kami̇l Teber, Fi̇li̇z Kizilirmak Yilmaz, Beytullah Çakal, Bi̇lal Boztosun
Turkish Journal of Medical Sciences
Background/aim: Myocarditis in the acute phase usually presents with sinus tachycardia but many other arrhythmias might be seen as well. In this study we aimed to investigate repolarization abnormalities in baseline ECG of patients with myocarditis for the first time.Materials and methods: Thirty patients diagnosed with myocarditis and 25 healthy age-matched controls were included. Two different cardiologists measured corrected QT (QTc), QT dispersion (QTd), QT peak (QTp), T wave peak to T wave end (TpTe), TpTe/QT ratio, and TpTe/QTc ratio in 12-lead ECG.Results: When compared with the control group, QTp (P: 0.021), QT (P: 0.003), TpTe (P < 0.001), TpTe/QTc ratio (P < 0.001), and TpTe/QT ratio (P: 0.005) were significantly higher in patients with myocarditis. A comparison of receiver operating characteristic (ROC) curves was conducted using the Hanley and McNeil method. The area under the curve (AUC) of the electrocardiographic characteristics QT (AUC: 0.736; 95% CI [0.600-0.846]), QTP (AUC: 0.680; 95% CI [0.540-0.799]), and TpTe (AUC: 0.771; 95% CI [0.638-873]) and TpTe/QTc (AUC: 0.774; 95% CI [0.641-0.876]) and TpTe/QT (AUC: 0.726; 95% CI [0.589-0.838]) in myocarditis were not significantly different from each other but all of them were different from 0.5.Conclusion: Baseline ECGs of patients with myocarditis were associated with repolarization abnormalities. These novel findings may be one of the reasons underlying arrhythmic events in patients with myocarditis.
Egfr, Kras, And Braf Mutational Profiles Of Female Patients With Micropapillary Predominant Invasive Lung Adenocarcinoma, Funda Demi̇rağ, Aydin Yilmaz, Ni̇lgün Yilmaz Demi̇rci̇, Ülkü Yilmaz, Yurdanur Erdoğan
Egfr, Kras, And Braf Mutational Profiles Of Female Patients With Micropapillary Predominant Invasive Lung Adenocarcinoma, Funda Demi̇rağ, Aydin Yilmaz, Ni̇lgün Yilmaz Demi̇rci̇, Ülkü Yilmaz, Yurdanur Erdoğan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to analyze EGFR, KRAS, and BRAF mutations in females with micropapillary predominant invasive lung adenocarcinoma and their relationships with immunohistochemical and clinicopathological patterns.Materials and methods: A total of 15 females with micropapillary lung adenocarcinoma were selected. Mutational analysis of the EGFR, KRAS, and BRAF genes was carried out. Information regarding the demographic data, tumor size, treatment, and survival time for each patient was collated, and the predominant cell type, secondary architectural growth patterns, psammoma bodies, necrosis, and visceral pleural and angiolymphatic invasions were evaluated.Results: We identified EGFR mutation in six cases, KRAS mutation in three cases, …
Quality Of Life And Fall Risk In Frail Hospitalized Elderly Patients, Zeynel Abi̇di̇n Öztürk, Sedat Özdemi̇r, İbrahi̇m Hali̇l Türkbeyler, Zeynep Demi̇r
Quality Of Life And Fall Risk In Frail Hospitalized Elderly Patients, Zeynel Abi̇di̇n Öztürk, Sedat Özdemi̇r, İbrahi̇m Hali̇l Türkbeyler, Zeynep Demi̇r
Turkish Journal of Medical Sciences
Background/aim: Frailty is a complex, multifactorial, and important geriatric syndrome characterized by decline in physiological reserves and functional deficiency in multiple systems. The aim of the current study is to investigate the prevalence of frailty and to determine the correlation between quality of life (QoL) and falling risk in geriatric hospitalized patients. Materials and methods: A total of 420 patients, aged 65 years and above, were enrolled in the study. All participants were hospitalized at a university hospital in the internal medicine clinics. The Cardiovascular Health Study (CHS) frailty scale, Health-Related Quality of Life Short Form (SF-36) scale, and Hendrich …
Unknown Vascular Compression Of The Airway In Patients With Congenitalheart Disease And Persistent Lower Respiratory Symptoms, Tuğba Şi̇şmanlar Eyüboğlu, Ayşe Tana Aslan, Çi̇ğdem Öztunali, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Serdar Kula, Betül Emi̇ne Deri̇nkuyu, Öznur Leman Boyunaga
Unknown Vascular Compression Of The Airway In Patients With Congenitalheart Disease And Persistent Lower Respiratory Symptoms, Tuğba Şi̇şmanlar Eyüboğlu, Ayşe Tana Aslan, Çi̇ğdem Öztunali, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Serdar Kula, Betül Emi̇ne Deri̇nkuyu, Öznur Leman Boyunaga
Turkish Journal of Medical Sciences
Background/aim: Airway compression (AC) by vascular structures is an important complication of congenital heart disease (CHD) that often goes unrecognized. It is not easy to identify whether CHD patients require additional invasive examinations or not. Therefore, the present study aims to develop an AC diagnostic algorithm for CHD patients. Materials and methods: CHD patients with persistent respiratory symptoms that were treated between January 2007 and December 2015 were retrospectively reviewed. The following data were recorded for all CHD patients with AC: age, cardiac anomalies, the compressed structure, the airway diameter ratio (ADR), the compressing structure(s), treatment, and follow-up.Results: During the …
Evaluation Of The General Characteristics Of Patients Aged 85 Years And Above Admitted To A University Hospital Emergency Department, Ahmet Demi̇rcan, Şahender Gülbi̇n Aygencel Bikmaz, Gülteki̇n Kadi, Ayfer Keleş, Fi̇kret Bi̇ldi̇k, Begüm Öktem, Onur Çakmak
Evaluation Of The General Characteristics Of Patients Aged 85 Years And Above Admitted To A University Hospital Emergency Department, Ahmet Demi̇rcan, Şahender Gülbi̇n Aygencel Bikmaz, Gülteki̇n Kadi, Ayfer Keleş, Fi̇kret Bi̇ldi̇k, Begüm Öktem, Onur Çakmak
Turkish Journal of Medical Sciences
Background/aim: The number of elderly people ($\ge$65 years old) is increasing both in Turkey and internationally due to improved living conditions and decreased mortality rates. Knowing the characteristics of elderly patients admitted to emergency departments can provide guidance for diagnosis and treatment approaches. In this study, we analyzed the characteristics of very old patients (4$\ge$85 years old) admitted to the emergency department and put together data for use in forward planning in healthcare services.Materials and methods: This retrospective study included all patients aged $\ge$85 years admitted to the Adult Emergency Department of Gazi University Medical Faculty Hospital between 01.01.2014 and …
Comparison Of The Cardioprotective Effects Of Dexmedetomidineand Remifentanil In Cardiac Surgery, Medi̇ha Türktan, Yasemi̇n Güneş, Hafi̇ze Yaliniz, Selçuk Matyar, Zehra Hati̇poğlu, Ersel Güleç, Uğur Göçen, Atakan Atalay
Comparison Of The Cardioprotective Effects Of Dexmedetomidineand Remifentanil In Cardiac Surgery, Medi̇ha Türktan, Yasemi̇n Güneş, Hafi̇ze Yaliniz, Selçuk Matyar, Zehra Hati̇poğlu, Ersel Güleç, Uğur Göçen, Atakan Atalay
Turkish Journal of Medical Sciences
Background/aim: Myocardial protection is an important factor of open heart surgery and biological biomarkers (lactate, CKMB, cardiac troponin I, and pyruvate) are used to assess myocardial damage. This study compares the effects of dexmedetomidine and remifentanil on myocardial protection during coronary artery bypass grafting (CABG) surgery. Materials and methods: Patients scheduled for elective CABG surgery (n = 60) were included in this study. Anesthesia induction was introduced with propofol, fentanyl, and vecuronium bromide. Anesthesia was maintained with remifentanil infusion and sevoflurane in the remifentanil group (Group R) and with dexmedetomidine infusion and sevoflurane in the dexmedetomidine group (Group D). Blood …
Role Of Baseline Adenoma Characteristics For Adenoma Recurrencein Patients With High-Risk Adenoma, Tevfi̇k Solakoğlu, Hüseyi̇n Köseoğlu, Sevi̇l Özer Sari, Fatma Ebru Akin, Ayli̇n Demi̇rezer Bolat, Öykü Tayfur Yürekli̇, Naci̇ye Şemnur Büyükaşik, Osman Ersoy
Role Of Baseline Adenoma Characteristics For Adenoma Recurrencein Patients With High-Risk Adenoma, Tevfi̇k Solakoğlu, Hüseyi̇n Köseoğlu, Sevi̇l Özer Sari, Fatma Ebru Akin, Ayli̇n Demi̇rezer Bolat, Öykü Tayfur Yürekli̇, Naci̇ye Şemnur Büyükaşik, Osman Ersoy
Turkish Journal of Medical Sciences
Background/aim: The present observational study aimed to determine the predictive value of 3-year recurrence adenoma characteristics at baseline conventional colonoscopy in patients with high-risk adenoma.Materials and methods: A total of 47 patients with high-risk adenoma at baseline colonoscopy were followed up and underwent a surveillance colonoscopy at 3 years. Correlations between adenoma recurrence and baseline adenoma characteristics (size, number, histological features, and location) were analyzed.Results: Among 135 patients with high-risk adenoma, 47 patients (35%) who underwent surveillance colonoscopy at 3 years following baseline colonoscopy were included in the study. In these 47 patients, at least one new adenoma was detected …
Effect Of Treatment Of Iron Deficiency Anemia Onhemoglobin A1c In Type 2 Diabetic Patients, Ensieh Nasli-Esfahani, Bagher Larijani, Peyvand Amini, Robabeh Ghodsi Ghasemabadi, Rezvan Razmandeh
Effect Of Treatment Of Iron Deficiency Anemia Onhemoglobin A1c In Type 2 Diabetic Patients, Ensieh Nasli-Esfahani, Bagher Larijani, Peyvand Amini, Robabeh Ghodsi Ghasemabadi, Rezvan Razmandeh
Turkish Journal of Medical Sciences
Background/aim: Iron deficiency anemia (IDA) affects hemoglobin A1c (HbA1c) levels. This study aimed to evaluate the effect of treatment of iron deficiency anemia on hemoglobin A1c in type 2 diabetic patients.Materials and methods: Ninety type 2 diabetes mellitus (T2DM) patients with IDA were included in a randomized, placebo-controlled, single-blind clinical trial. The intervention group (n = 45) received 200 mg/day oral iron for 3 months and the control group (n = 45) received an oral placebo for the same period. Fasting blood sugar, complete blood count, and HbA1c were measured for all subjects at the beginning and the end of …
Investigation Of Human Leukocyte Antigen In Osteoarticular Brucellosis, Sevi̇m Gönen, Murat Di̇zbay, Hüsnü Oğuz Söylemezoğlu
Investigation Of Human Leukocyte Antigen In Osteoarticular Brucellosis, Sevi̇m Gönen, Murat Di̇zbay, Hüsnü Oğuz Söylemezoğlu
Turkish Journal of Medical Sciences
Background/aim: To determine the relationship between human leukocyte antigen (HLA) antigens and osteoarticular brucellosis by evaluating HLA Class I and II antigens in control subjects and patients developing osteoarticular brucellosis in Turkey.Materials and methods: The study included 28 patients with osteoarticular involvement diagnosed with brucellosis and 100 controls. The HLA Class I and II antigens were studied in isolated DNA samples using sequence-specific oligonucleotide procedure.Results: The mean age of the 28 patients and 100 controls was 42.3 $\pm$ 20.2 years and 50.1 $\pm$ 16.3 years, respectively. When the frequency of HLA Class I was examined, HLA-A*02 and HLA-B*27 antigens were …