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2017

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Articles 11251 - 11280 of 14524

Full-Text Articles in Medicine and Health Sciences

Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay Jan 2017

Epidemiology Of Under-Five Mortality In İstanbul: Changes From 1988 To 2011, Fahri̇ye Aysun Buzcu, Ayli̇n Yeti̇m Şahi̇n, Esra Karapinar, Özge Erol, Emi̇ne Gülbi̇n Gökçay

Turkish Journal of Medical Sciences

Background/aim: Understanding the causes of under-five deaths is key to realizing sustainable developmental goals. The aim of this descriptive study was to investigate the causes of under-five mortality in İstanbul during 2011 and compare the findings to those of 1988 and 2000. Materials and methods: All burial records of İstanbul were evaluated, and cemetery records of 1494 children, who died at under five years of age and were buried in İstanbul Metropolitan Municipality Cemeteries between 1 January and 31 December 2011, were analyzed. Several sociodemographic characteristics and causes of death were compared with the results of studies carried out in …

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Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur Jan 2017

Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate the epidemiologic characteristics, the causative microorganisms and their antimicrobial susceptibility patterns, and the prognostic risk factors for mortality in critically ill patients with ventilator-associated pneumonia (VAP). Materials and methods: In this retrospective observational study, all the critically ill patients with VAP hospitalized in a medical/surgical intensive care unit (ICU) between January 2010 and June 2015 were evaluated. Patients' demographic features and microbiological data were reviewed. Results: A total of 417 patients were clinically diagnosed with VAP; 51.1% of them were male and the average age was found as 69.9 ± 15.9 …

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Performing Icsi With Commercial Microinjection Pipettes Enhanced Pregnancy Rates, Mohammad Ali Khalili, Iman Halvaei, Shahin Ghazali, Mohammad Hossein Razi Jan 2017

Performing Icsi With Commercial Microinjection Pipettes Enhanced Pregnancy Rates, Mohammad Ali Khalili, Iman Halvaei, Shahin Ghazali, Mohammad Hossein Razi

Turkish Journal of Medical Sciences

Background/aim: Many technical factors can affect intracytoplasmic sperm injection (ICSI) outcomes. The role of the injection micropipette could be of vital importance in ICSI programs. The main goal was to compare ICSI pregnancy outcomes between commercial and home-made injection micropipettes in a large population with male factor infertility. Materials and methods: Five-hundred and eleven ICSI cycles with severe male factor were included in this retrospective study. ICSI cycles were divided into two groups: A (home-made micropipettes, n = 267) and B (commercial micropipettes, n = 244). Rates of fertilization, embryo formation, and chemical and clinical pregnancies were compared between the …

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Evaluation Of Quality Of Life And Cost-Effectiveness Of Definitive Surgery And The Levonorgestrel Intrauterine System As Treatment Options For Heavy Menstrual Bleeding, Cevdet Adigüzel, Sevtap Seyfetti̇noğlu, Deni̇z Aka Satar, Sefa Arlier, Eda Eski̇mez, Fatma Kaya, Hakan Nazi̇k Jan 2017

Evaluation Of Quality Of Life And Cost-Effectiveness Of Definitive Surgery And The Levonorgestrel Intrauterine System As Treatment Options For Heavy Menstrual Bleeding, Cevdet Adigüzel, Sevtap Seyfetti̇noğlu, Deni̇z Aka Satar, Sefa Arlier, Eda Eski̇mez, Fatma Kaya, Hakan Nazi̇k

Turkish Journal of Medical Sciences

Background/aim: This study aimed to compare the levonorgestrel intrauterine system (LNG-IUS) with abdominal hysterectomy (TAH) and total laparoscopic hysterectomy (TLH) as first-line treatments for heavy menstrual bleeding (HMB). Materials and methods: Ninety-eight patients aged 20-55 years who complained of regular heavy menstrual bleeding were enrolled in the study. The TAH group included 29 patients, the LNG-IUS group included 34, and the TLH group included 35. These groups were compared in terms of quality of life and the cost-effectiveness of the selected methods. Quality of life was assessed using the 36-Item Short Form (SF-36), and cost-effectiveness was assessed according to the …

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The Relationship Between Sleep Quality And Depressive Symptoms In Adolescents, Begüm Dağ, Fatma Yasemi̇n Kutlu Jan 2017

The Relationship Between Sleep Quality And Depressive Symptoms In Adolescents, Begüm Dağ, Fatma Yasemi̇n Kutlu

Turkish Journal of Medical Sciences

Background/aim: While poor sleep quality and sleep problems are signs of depression in adolescents, depressive symptoms among this age group further deteriorate sleep quality. The aim of this study was to explore the relationship between sleep quality and depressive symptoms in adolescents of 14 to 20 years of age. Materials and methods: This study was conducted with a descriptive and cross-sectional research design. The sample group consisted of 313 adolescents in İstanbul, Turkey. The data were collected using a questionnaire form, the Beck Depression Inventory (BDI), and the Pittsburgh Sleep Quality Index (PSQI). Results: The mean BDI score of the …

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The Influence Of Intraabdominal Pressure On The Mortalityrate Of Patients With Acute Pancreatitis, Petar Svorcan, Maja Stojanovic, Predrag Stevanovic, Aleksandar Karamarkovic, Radmilo Jankovic, Nebojsa Ladjevic Jan 2017

The Influence Of Intraabdominal Pressure On The Mortalityrate Of Patients With Acute Pancreatitis, Petar Svorcan, Maja Stojanovic, Predrag Stevanovic, Aleksandar Karamarkovic, Radmilo Jankovic, Nebojsa Ladjevic

Turkish Journal of Medical Sciences

Background/aim: Intraabdominal hypertension (IAH) is a common clinical finding in patients with acute pancreatitis and is associated with poor prognosis. This study aimed to determine the impact of intraabdominal pressure (IAP) on the mortality rate in patients with acute pancreatitis in an intensive care unit. Materials and methods: A total of 50 patients with acute pancreatitis were included in this prospective cohort study. Based on the obtained values of IAP, the patients were divided into two groups: those with normal IAP (n = 14) and increased IAP (n = 36). Mean values of IAP were compared with examined variables. Results: …

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Prevalence And Risk Factors For Vitamin D Deficiency In Patientswith Widespread Musculoskeletal Pain, Muharrem Çi̇dem, Ilhan Karacan, Ozan Beytemür, Seher Kara Jan 2017

Prevalence And Risk Factors For Vitamin D Deficiency In Patientswith Widespread Musculoskeletal Pain, Muharrem Çi̇dem, Ilhan Karacan, Ozan Beytemür, Seher Kara

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to examine the prevalence of 25-hydroxyvitamin D (25(OH) vitamin D) deficiency in patients complaining of widespread musculoskeletal pain. Materials and methods: In this cross-sectional study, 14,925 patients (13,589 females and 1336 males; mean age: 47.0 years, range: 20-99 years) were included. Serum 25(OH) vitamin D was measured by ELISA. The patients were classified into two groups: 1) patients with vitamin D deficiency (<20 ng/mL) and 2) patients without vitamin D deficiency (>20 ng/mL). Results: The prevalence of vitamin D deficiency was 73.9%. A multivariate logistic regression model showed that low 25(OH) vitamin D level was associated with sex, age, and month …

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Evaluation And Comparison Of Radiologic-Pathologic Findings In Invasive Cribriform Carcinoma Of The Breast, Pinar Balci, Işil Başara Akin, Nevi̇n Köremezli̇, Meri̇h Güray Durak, Canan Altay, Naci̇ye Si̇nem Gezer, Ali̇ İbrahi̇m Sevi̇nç Jan 2017

Evaluation And Comparison Of Radiologic-Pathologic Findings In Invasive Cribriform Carcinoma Of The Breast, Pinar Balci, Işil Başara Akin, Nevi̇n Köremezli̇, Meri̇h Güray Durak, Canan Altay, Naci̇ye Si̇nem Gezer, Ali̇ İbrahi̇m Sevi̇nç

Turkish Journal of Medical Sciences

Background/aim: This study aimed to report invasive cribriform carcinoma (ICC) with radiological and histopathologic correlations. Materials and methods: Seventy patients with ICC were classified into two groups; pure ICC patients and patients with >50% cribriform carcinoma component were included in group 1, while patients with <50% cribriform carcinoma component were included in group 2. All patients were reviewed according to American College of Radiology (ACR) breast imaging reporting and data system (BI-RADS) lexicon of mammography (MG), ultrasonography (US), and magnetic resonance imaging (MRI). One-way analysis of variance tests and t-tests were used for analysis. P < 0.05 was accepted as statistically significant. Results: Eighteen patients were in group 1 and 52 were in group 2. All patients had MG and US, while 24 patients needed MRI. According to MG ACR BI-RADS lexicon evaluation, irregular shape, spiculated margin and indistinct margin, and high density were statistically significantly higher in group 2 than the other group (respectively P = 0.001, P = 0.001, and P= 0.04). Equal density was statistically significantly higher in group 1 than the other group (P = 0.008). According to US ACR BI-RADS lexicon evaluation, irregular shape, spiculated margins, angular margins, microlobulated margins, and nonparallel orientation were more common US findings in group 2 than the other group (respectively P = 0.001, P = 0.001, P = 0.003, P = 0.04, and P = 0.04). The rate of parallel orientation was higher in group 1 than the other group (P = 0.02). Conclusion: Few cases showed benign characteristics and most ICCs appear with typical features of malignancy. Radiologic features of ICC could be better understood and would be helpful for radiologists in diagnosing this rare type of malignancy.

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Social Support And Quality Of Life In A Group Of Cancer Patients (Ankara, Turkey), Mustafa Soner Yilmaz, Bi̇rgül Pi̇yal, Recep Akdur Jan 2017

Social Support And Quality Of Life In A Group Of Cancer Patients (Ankara, Turkey), Mustafa Soner Yilmaz, Bi̇rgül Pi̇yal, Recep Akdur

Turkish Journal of Medical Sciences

Background/aim: Cancer has become an important public health challenge all around the world. Though the demographic and clinical features of cancer patients are well documented in Turkey, the establishment of social support networks has been somewhat neglected. The aim of the study was to assess cancer patients' perceived social support and quality of life characteristics. Materials and methods: The Multidimensional Perceived Social Support Scale, European Organization of Research and Treatment of Cancer Quality of Life Questionnaire, and Turkish version of the EUROHIS measurements were obtained from the study group. Associations between the scores and sociodemographic variables of the patients were …

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Association Study Of Ctla-4 +49a/G Gene Polymorphism With Recurrentpregnancy Loss In The Iranian Azeri Turkish Ethnic Group, Mortaza Bonyadi, Sara Parsa, Simin Taghavi, Narges Zeinalzadeh Jan 2017

Association Study Of Ctla-4 +49a/G Gene Polymorphism With Recurrentpregnancy Loss In The Iranian Azeri Turkish Ethnic Group, Mortaza Bonyadi, Sara Parsa, Simin Taghavi, Narges Zeinalzadeh

Turkish Journal of Medical Sciences

Background/aim: Recurrent pregnancy loss (RPL) is defined as two or more pregnancy losses. T-regulatory cells play an important role in the feto-maternal interface. Cytotoxic-T-lymphocyte antigen-4 (CTLA-4) is a molecule that downregulates the activation and proliferation of T cells. The objective of the current study was to investigate the possible association of CTLA-4+49A/G gene polymorphism with RPL among patients from the Iranian Azeri Turkish ethnic group. Materials and methods: The study group/patients consisted of 101 women with the experience of two or more pregnancy losses and the control group consisted of 101 women with at least two live births, without any …

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Vitamin E As A Novel Therapy In The Treatment Of Acute Aluminum Phosphide Poisoning, Zahra Halvaei, Hiva Tehrani, Kambiz Soltaninejad, Mohammad Abdollahi, Shahin Shadnia Jan 2017

Vitamin E As A Novel Therapy In The Treatment Of Acute Aluminum Phosphide Poisoning, Zahra Halvaei, Hiva Tehrani, Kambiz Soltaninejad, Mohammad Abdollahi, Shahin Shadnia

Turkish Journal of Medical Sciences

Background/aim: Aluminum phosphide (AlP) is commonly used as a fumigant in developing countries. Induction of oxidative stress is one of the most important mechanisms of its toxicity. In this regard, and considering that there is no specific antidote for its treatment, the aim of this study was to evaluate the effect of vitamin E in the treatment of acute AlP poisoning. Materials and methods: This was a clinical trial on acute AlP poisoned patients. All patients received supportive treatment. In addition, the treatment group received vitamin E (400 mg/BD/IM). Level of malondialdehyde (MDA) and total antioxidant capacity of plasma were …

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Relationship Between Blood Glucose Levels And Cardiovascular Risk In The Spanish Mediterranean Population, Angel Arturo Lopez Gonzalez, Zoe Manzanero, Maria Teofila Vicente-Herrero, Sheila Garcia-Agudo, Maria Gil-Llinas, Francisco Moreno-Morcillo Jan 2017

Relationship Between Blood Glucose Levels And Cardiovascular Risk In The Spanish Mediterranean Population, Angel Arturo Lopez Gonzalez, Zoe Manzanero, Maria Teofila Vicente-Herrero, Sheila Garcia-Agudo, Maria Gil-Llinas, Francisco Moreno-Morcillo

Turkish Journal of Medical Sciences

Background/aim: Diabetes is associated with an increased prevalence of cardiovascular disease. Impaired fasting glucose (IFG) is an intermediate clinical situation between normal glucose levels and type 2 diabetes. The aim of this study is to determine how fasting glucose concentrations affect different cardiovascular risk scales. Materials and methods: A descriptive study was conducted with 59,041 Mediterranean Spanish workers. IFG was determined using the American Diabetes Association (ADA) and the World Health Organization (WHO) criteria. Different indicators of cardiovascular risk were analyzed: body mass index, waist circumference, waist-to-height ratio, blood pressure, lipid parameters, atherogenic indices, metabolic syndrome, and various scales of …

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Impact Of Adjuvant Treatment On Oncologic Outcomes Inpatients With Stage I Leiomyosarcoma Of The Uterus, Gökhan Boyraz, Derman Başaran, Mehmet Coşkun Salman, Nejat Özgül, Kunter Yüce Jan 2017

Impact Of Adjuvant Treatment On Oncologic Outcomes Inpatients With Stage I Leiomyosarcoma Of The Uterus, Gökhan Boyraz, Derman Başaran, Mehmet Coşkun Salman, Nejat Özgül, Kunter Yüce

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the role of adjuvant therapy for stage I uterine leiomyosarcoma (LMS). Materials and methods: Clinicopathological data of cases of stage I uterine LMS from 1998 to 2015 were retrieved from the computerized database of Hacettepe University Hospital. The Kaplan-Meier method was used to estimate survival and progression-free survival, and survival differences were analyzed by log-rank test. Cox regression analysis was performed to account for the potential influence of confounding factors. Results: We evaluated the outcomes of 35 patients with histologically proven stage I LMS. The median age at diagnosis was 50 years. All patients …

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A Comparison Of Usage Of The Laryngeal Mask Uniquetmin Denticulate And Edentulate Geriatric Patients, Meltem Genez, Semi̇h Küçükgüçlü, Şule Özbi̇lgi̇n, Bahar Kuvaki̇ Balkan, Tangül Beydeş, Melek Aksoy Sari Jan 2017

A Comparison Of Usage Of The Laryngeal Mask Uniquetmin Denticulate And Edentulate Geriatric Patients, Meltem Genez, Semi̇h Küçükgüçlü, Şule Özbi̇lgi̇n, Bahar Kuvaki̇ Balkan, Tangül Beydeş, Melek Aksoy Sari

Turkish Journal of Medical Sciences

Background/aim: Mask ventilation in geriatric and edentulous patients can be ineffective or even impossible because of the shape inside the patients' cheeks. For patients for whom a mask cannot be used for long, the use of a laryngeal mask can ease the administration of anesthesia. The aim of this study was to compare the use of the laryngeal mask UniqueTM in denticulate and edentulate patients aged over 65 years. Materials and methods: This prospective study included patients according to the American Society of Anesthesiologists I-III classification, aged 65 years or more. The patients were divided into two groups: a dentulous …

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Three-Layer Primary Closure Of The Bipedicled Tram Flap Donor Site For Unilateralbreast Reconstruction: A 15-Year Experience With 124 Consecutive Patients, Hüseyi̇n Karagöz, Ci̇han Şahi̇n, Celaletti̇n Sever, Yalçin Külahci, Fi̇kret Eren, Ceyhun Cesur, Fuat Yüksel Jan 2017

Three-Layer Primary Closure Of The Bipedicled Tram Flap Donor Site For Unilateralbreast Reconstruction: A 15-Year Experience With 124 Consecutive Patients, Hüseyi̇n Karagöz, Ci̇han Şahi̇n, Celaletti̇n Sever, Yalçin Külahci, Fi̇kret Eren, Ceyhun Cesur, Fuat Yüksel

Turkish Journal of Medical Sciences

Background/aim: The pedicled transverse rectus abdominis myocutaneous (TRAM) flap remains widely used as a breast reconstruction technique. The bipedicled TRAM flap is not as preferable as it was formerly, mainly because of its donor site complications. However, in a number of situations, a bipedicled TRAM flap may be the only alternative. Therefore, a three-layer primary closure technique used with bipedicled TRAM flap breast reconstructions that can avoid donor site complications without using a mesh is presented. Materials and methods: A retrospective study was performed that included patients who underwent bipedicled TRAM flap breast reconstruction with the three-layer primary closure technique. …

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Frequency Of Human Parvovirus 4 (Parv4) Viremia Among Hbv-Infected Patients And Healthy Donors In Shiraz, Iran, Fereshte Amirahmadi, Jamal Sarvari, Seyed Younes Hosseini, Neda Pirbonyeh, Ali Akbar Gorzin Jan 2017

Frequency Of Human Parvovirus 4 (Parv4) Viremia Among Hbv-Infected Patients And Healthy Donors In Shiraz, Iran, Fereshte Amirahmadi, Jamal Sarvari, Seyed Younes Hosseini, Neda Pirbonyeh, Ali Akbar Gorzin

Turkish Journal of Medical Sciences

Background/aim: PARV4, a small DNA virus belonging to the family Parvoviridae, was first isolated in an HBV injecting drug user. Several studies have investigated PARV4 co-infection with HBV and HCV and its effect on the progression of liver disease. The aim of this study was to determine the frequency of PARV4 among HBV-infected patients and healthy individuals. Materials and methods: A group of 90 HBV patients and a group of 90 healthy subjects were included in this study. Samples were selected after screening tests such as HBsAg ELISA, anti-HCV ELISA, and anti-HIV ELISA. Nested-PCRs were conducted to detect the PARV4 …

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Screening Of Immunocompromised Patients At Risk Of Strongyloidiasis In Western Turkey Using Elisa And Real-Time Pcr, Esra Erdem Kivrak, Esra Atalay Şahar, Hüseyi̇n Can, Mert Döşkaya, Mümtaz Yilmaz, Hüsnü Pullukçu, Ayşe Caner, Hüseyi̇n Töz, Adnan Yüksel Gürüz, Meltem Işikgöz Taşbakan Jan 2017

Screening Of Immunocompromised Patients At Risk Of Strongyloidiasis In Western Turkey Using Elisa And Real-Time Pcr, Esra Erdem Kivrak, Esra Atalay Şahar, Hüseyi̇n Can, Mert Döşkaya, Mümtaz Yilmaz, Hüsnü Pullukçu, Ayşe Caner, Hüseyi̇n Töz, Adnan Yüksel Gürüz, Meltem Işikgöz Taşbakan

Turkish Journal of Medical Sciences

Background/aim: Strongyloides stercoralis causes life-threatening hyperinfection or disseminated strongyloidiasis in immunocompromised patients such as HIV-positive, organ transplantation, and cancer patients. This study investigated the presence of strongyloidiasis in immunocompromised patients for the first time in Turkey. Materials and methods: Serum and stool samples were collected from 108 patients (25.9% of them were chronic renal failure and 74.1% were renal transplantation patients) who were admitted to Ege University Medical School in İzmir, located in western Turkey. Serum samples were analyzed by ELISA (DRG, Germany) and the presence of 18S rRNA gene of S. stercoralis was detected in stool samples by real-time …

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Routine Assessment Of Occupational Exposure And Its Relation To Semen Quality In Infertile Men: A Cross-Sectional Study, Salima Daoud, Afifa Sellami, Mehdi Bouassida, Sahbi Kebaili, Leila Ammar Keskes, Tarek Rebai, Nozha Chakroun Feki Jan 2017

Routine Assessment Of Occupational Exposure And Its Relation To Semen Quality In Infertile Men: A Cross-Sectional Study, Salima Daoud, Afifa Sellami, Mehdi Bouassida, Sahbi Kebaili, Leila Ammar Keskes, Tarek Rebai, Nozha Chakroun Feki

Turkish Journal of Medical Sciences

Background/aim: Concerns about the detrimental effects of occupational and environmental exposure on male reproductive function have been raised by reports of declining sperm quality over the last decades. The aim of this study was to investigate the association between altered semen parameters and exposure to occupational risk factors as assessed by questionnaire. Materials and methods: We conducted a cross-sectional questionnaire-based study among a population of 2122 men who underwent andrological investigation for couple infertility. All participants were interviewed and their semen samples were analyzed. Information about medical history and occupational exposure was used to classify participants into exposed and unexposed …

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Male Infertility Is Significantly Associated With Multiple Deletions In An 8.7-Kb Segment Of Sperm Mtdna In Pakistan, Irfan Afzal Mughal, Asma Irfan, Sarwat Jahan, Abdul Hameed Jan 2017

Male Infertility Is Significantly Associated With Multiple Deletions In An 8.7-Kb Segment Of Sperm Mtdna In Pakistan, Irfan Afzal Mughal, Asma Irfan, Sarwat Jahan, Abdul Hameed

Turkish Journal of Medical Sciences

Background/aim: This study aimed to find a link between sperm mitochondrial DNA mutations and male infertility in Pakistan. Materials and methods: DNA from semen samples was extracted and amplified by PCR using 7.8-kb deletion-specific primers. The PCR products were separated on agarose gel, visualized under UV-illumination, and then photographed. The results were genotyped and the data were analyzed using SPSS. Results: Deletion analysis of the 8.7-kb fragment by long PCR revealed multiple deletions. The frequency of deletion was much higher in infertile groups as compared to the control group. Further, on comparison between different subtypes of infertile groups, the deletions …

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Serum Ischemic Modified Albumin (Ima) Concentration And Ima/Albumin Ratio In Patients With Hepatitis B-Related Chronic Liver Diseases, Fatma Yavuz, Murat Biyik, Mehmet Asil, Ramazan Dertli̇, Ali̇ Demi̇r, Hakki Polat, Sali̇ha Uysal, Hüseyi̇n Ataseven Jan 2017

Serum Ischemic Modified Albumin (Ima) Concentration And Ima/Albumin Ratio In Patients With Hepatitis B-Related Chronic Liver Diseases, Fatma Yavuz, Murat Biyik, Mehmet Asil, Ramazan Dertli̇, Ali̇ Demi̇r, Hakki Polat, Sali̇ha Uysal, Hüseyi̇n Ataseven

Turkish Journal of Medical Sciences

Background/aim: Albumin is the most important protein synthesized by the liver. Posttranscriptional changes occur in the molecular structure of albumin due to various factors and isoforms arise. Ischemic modified albumin (IMA) is one such isoform. This study was conducted to evaluate serum IMA concentrations in patients with hepatitis B virus (HBV)-related chronic liver diseases. Materials and methods: This study included 74 treatment-naive chronic hepatitis B patients, 25 patients with HBV-related cirrhosis, and 49 healthy controls. Serum IMA concentration was measured spectrophotometrically using the albumin cobalt binding test. Results: The mean IMA concentrations in the chronic hepatitis B group and healthy …

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Morphometric Study Of The True S1 And S2 Of The Normal Anddysmorphic Sacralized Sacra, Ayşegül Firat, Kadi̇r Bahadir Alemdaroğlu, Ahmet Özmeri̇ç, Mehmet Yücens, Di̇nçer Göksülük Jan 2017

Morphometric Study Of The True S1 And S2 Of The Normal Anddysmorphic Sacralized Sacra, Ayşegül Firat, Kadi̇r Bahadir Alemdaroğlu, Ahmet Özmeri̇ç, Mehmet Yücens, Di̇nçer Göksülük

Turkish Journal of Medical Sciences

Background/aim: This study aimed to generate data for the S1 and S2 alar pedicle and body and the alar orientations for both dysmorphic and normal sacra. Materials and methods: The study comprised two groups: Group N consisted of 53 normal sacra and Group D included 10 dysmorphic sacra. Various features such as alar pedicle circumference; anterior, middle, and posterior axis of the sacral ala; sacral body height and width; and sagittal thickness were measured. Results: In group N, the median anterior axis of the alae was observed to be 30° on the right and 25° on the left, the median …

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Frequency And Molecular Characterization Of Human Norovirus In Erzurum, Turkey, Mehmet Özkan Ti̇murkan, Hakan Aydin, Osman Aktaş Jan 2017

Frequency And Molecular Characterization Of Human Norovirus In Erzurum, Turkey, Mehmet Özkan Ti̇murkan, Hakan Aydin, Osman Aktaş

Turkish Journal of Medical Sciences

Background/aim: There are limited studies on genotyping and phylogenetic analysis of norovirus in Turkey, and this has not previously been studied in the Eastern Anatolia region. The aim of the present study was to determine the norovirus profile in this region with genotyping and phylogenetic analysis. Materials and methods: Included in the study were stool samples obtained from 427 people from different age groups in Eastern Anatolia. The nucleic acid samples isolated by the automatic system and nucleic acid sequence reactions and phylogenetic analyses were performed on RNA samples. Results: The presence of norovirus was detected in 86 (20.1%) of …

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Isolation Rates And Antibiotic Susceptibilities Of Different Enterobacteriaceae Species As Urinary Tract Infection Agents In Turkey: A Systematic Review, Caner Yürüyen, Yeşi̇m Gürol, Sabi̇re Ferda Kaleağasioğlu, Eli̇f Çi̇ğdem Kaspar, Gülden Yilmaz Jan 2017

Isolation Rates And Antibiotic Susceptibilities Of Different Enterobacteriaceae Species As Urinary Tract Infection Agents In Turkey: A Systematic Review, Caner Yürüyen, Yeşi̇m Gürol, Sabi̇re Ferda Kaleağasioğlu, Eli̇f Çi̇ğdem Kaspar, Gülden Yilmaz

Turkish Journal of Medical Sciences

Background/aim: In Turkey, few systematic reviews have analyzed the results of studies on the isolation rates of urinary tract infection agents and their antibiotic susceptibilities. This review was done to fill this gap and enable the correct application of guideline-based medical therapy by determining the isolation rates and antibiotic susceptibilities of different Enterobacteriaceae species in Turkey. Materials and methods: Relevant studies found from various databases with the help of previously specified search strategies were examined and eliminated according to eligibility criteria. The remaining 22 studies were included in this systematic review. Results: Escherichia coli was the most frequently isolated species …

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The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k Jan 2017

The Effect Of Acetylsalicylic Acid On Vasopressin, Serum Insulin Levels, Insulin Resistance, And Biochemical Parameters In Rats Induced With Experimental Diabetes Type 2, Serkan Şen, Sefa Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: Acetylsalicylic acid (ASA) treatment in diabetic patients is very important owing to the increasing hyperactivity of thrombocytes and atherosclerosis. In several investigations, it was reported that diabetes caused increased coronary artery disease, cerebrovascular disease, and death. In this study, we aimed to investigate the effect of ASA on osmoregulation, glycemic control, and some biochemical parameters in rats induced with experimental diabetes type 2. Materials and methods: Twenty-four rats were randomly divided in four groups: control (I), ASA control (II), diabetic (III), and ASA diabetic (IV). Diabetes was induced by streptozotocin treatment (30 mg/kg, twice, intraperitoneal injection) in obese rats. …

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Rational Design Of Rabies Vaccine Formulation For Enhanced Stability, Veysel Kayser, Alain Francon, Herve Pinton, Jean-Francois Saluzzo, Bernhardt L. Trout Jan 2017

Rational Design Of Rabies Vaccine Formulation For Enhanced Stability, Veysel Kayser, Alain Francon, Herve Pinton, Jean-Francois Saluzzo, Bernhardt L. Trout

Turkish Journal of Medical Sciences

Background/aim: Vaccines are often lyophilized in order to retain their stability and efficacy for a longer period of time. However, the same lyophilization process may also cause a major degradation of the vaccine, especially during early phases of manufacturing, leading to a loss of potency of the product. Many viral diseases, such as rabies, are acute and fatal unless the vaccine is administered prior to exposure or the onset of symptoms in the case of postexposure treatment. Materials and methods: We investigated the effect of lyophilization on the stability of the virus structure during rabies vaccine manufacturing using dynamic light …

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Changes In The Serum, Liver, And Renal Cortical Lipids And Electrolytesin Rabbits With Cisplatin-Induced Nephrotoxicity, Abdelgayoum Ahmed Abdel-Gayoum, Mohamed Hamza Sulaiman Ahmida Jan 2017

Changes In The Serum, Liver, And Renal Cortical Lipids And Electrolytesin Rabbits With Cisplatin-Induced Nephrotoxicity, Abdelgayoum Ahmed Abdel-Gayoum, Mohamed Hamza Sulaiman Ahmida

Turkish Journal of Medical Sciences

Background/aim: Cisplatin is an anticancer drug that can induce nephrotoxicity. Its toxicity is associated with dyslipidemia and disturbed electrolyte balance. In the present study we investigated the changes in serum lipid profile and electrolyte levels and their contents in kidney and liver tissues of rabbits treated with cisplatin. Materials and methods: Twenty-eight adult male New Zealand White rabbits were used in the experiment. Animals of groups C, P1, and P2 were injected with saline, cisplatin (4.0 mg/kg bw), and cisplatin (6.5 mg/kg bw), respectively, and killed 3 days after the injections. Animals of group R were given cisplatin (6.5 mg/kg …

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The Effects Of Iloprost And Alprostadil On Ischemia-Reperfusion Injury In Preventing Inflammation, Tissue Degeneration, And Apoptosis In Rat Skeletal Muscle, Eli̇f Güneysu, Atacan Emre Koçman, Orhan Özati̇k, Cengi̇z Ovali, Betül Can, İbrahi̇m Özkan Alataş, Mustafa Behçet Sevi̇n Jan 2017

The Effects Of Iloprost And Alprostadil On Ischemia-Reperfusion Injury In Preventing Inflammation, Tissue Degeneration, And Apoptosis In Rat Skeletal Muscle, Eli̇f Güneysu, Atacan Emre Koçman, Orhan Özati̇k, Cengi̇z Ovali, Betül Can, İbrahi̇m Özkan Alataş, Mustafa Behçet Sevi̇n

Turkish Journal of Medical Sciences

Background/aim: The protective effects of prostaglandin (PG) analogs on ischemia-reperfusion (I/R) have been well documented; however, comparative studies are lacking. The aim of the present study was to determine whether iloprost or alprostadil is more effective in preventing muscle I/R injury. Materials and methods: Thirty-two rats were divided into four groups (n = 8): sham, control, IL (I/R + iloprost), and AL (I/R + alprostadil). I/R was induced by a tourniquet in the hindlimb for 3 h/3 h. The IL and AL groups received iloprost (0.5 ng kg-1 min-1) and alprostadil (0.05 μg kg-1 min-1) during reperfusion, respectively. After 6 …

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Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca Jan 2017

Antiinflammatory And Antioxidant Effects Of Gemcitabinein Collagen-Induced Arthritis Model, Adi̇le Ferda Dağli, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Meti̇n Özgen, Kazi̇m Şahi̇n, Süleyman Serdar Koca

Turkish Journal of Medical Sciences

Background/aim: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on collagen-induced arthritis (CIA). Materials and methods: Arthritis was induced by the intradermal injection of chicken type II collagen with incomplete Freund's adjuvant into albino Wistar rats. Doses of 5 and 20 mg/kg GEM were administered twice a week after the 14th day, which marked the onset the arthritis. Serum IL-17, TNF-α, malondialdehyde, catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels and tissue heme oxygenase-1 (HO-1) and nuclear factor …

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Comparison Of Endothelin And Nitric Oxide Synthase Blockerson Hemorheological Parameters In Endotoxemic Rats, Nesli̇han Hacer Di̇kmenoğlu Falkmarken, Okan Arihan, Alper Bektaş İski̇t Jan 2017

Comparison Of Endothelin And Nitric Oxide Synthase Blockerson Hemorheological Parameters In Endotoxemic Rats, Nesli̇han Hacer Di̇kmenoğlu Falkmarken, Okan Arihan, Alper Bektaş İski̇t

Turkish Journal of Medical Sciences

Background/aim: Septic shock is an important health problem that vastly alters cardiovascular and hemodynamic status. Increased production of nitric oxide (NO) and endothelin is a counterpart of this endotoxemic state. This study was conducted to test the hypothesis that nonselective NO synthesis blocker (L-NAME), inducible NO synthesis blocker (L-canavanine), or endothelin receptor antagonist (bosentan) will reverse the effects of sepsis on hemorheological parameters. Materials and methods: Forty-eight male Sprague-Dawley rats were used in 8 groups: saline (control), endotoxin, bosentan, L-NAME, L-canavanine, endotoxin + bosentan, endotoxin + L-NAME, and endotoxin + L-canavanine. Blood was withdrawn at the 4th hour of endotoxemic …

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What Is The Rectal Colonization Rate Of Carbapenem-Resistant Enterobacteriaceae (Cre)-Infected Patients? What Is The Decolonization Rate Of Cre-Colonized Patients In The Hospital?, Fatma Feri̇ha Çi̇lli̇, Bi̇lgi̇n Arda, Ayşe Uyan, Münevver Kayin, Demet Di̇ki̇ş, Ni̇lay Korkmaz, Ni̇lgün Deni̇z Küçükler, Nurhayat Kepeli̇, Behi̇ye Ulusoy, Şükran Akşi̇t Barik, Mehmet Ali̇ Özi̇nel, Sercan Ulusoy, Oğuz Reşat Si̇pahi̇ Jan 2017

What Is The Rectal Colonization Rate Of Carbapenem-Resistant Enterobacteriaceae (Cre)-Infected Patients? What Is The Decolonization Rate Of Cre-Colonized Patients In The Hospital?, Fatma Feri̇ha Çi̇lli̇, Bi̇lgi̇n Arda, Ayşe Uyan, Münevver Kayin, Demet Di̇ki̇ş, Ni̇lay Korkmaz, Ni̇lgün Deni̇z Küçükler, Nurhayat Kepeli̇, Behi̇ye Ulusoy, Şükran Akşi̇t Barik, Mehmet Ali̇ Özi̇nel, Sercan Ulusoy, Oğuz Reşat Si̇pahi̇

Turkish Journal of Medical Sciences

No abstract provided.

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